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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2020 Volume 44 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Exploring the role of glucose‑6‑phosphate dehydrogenase in cancer (Review)

Rui Li, Wang Wang, Ye Yang, Chunyan Gu
Pages: 2325-2336
Published online on: 12 October 2020

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Review

Roles of the HGF/Met signaling in head and neck squamous cell carcinoma: Focus on tumor immunity (Review)

Dongjuan Liu, Ming Zhong, Desong Zhan, Ying Zhang, Sai Liu
Pages: 2337-2344
Published online on: 09 October 2020

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Review

Intrahepatic metastases may be specific to hepatocellular carcinoma due to the coagulation and fibrinolytic systems (Review)

Xuemei Li, Baohong Gu, Bofang Wang, Zedong Feng, Yanling Ma, Haiyuan Li, Alexandra Lucas, Hao Chen
Pages: 2345-2352
Published online on: 09 October 2020

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Review

Lipid‑based nanoparticles for the therapeutic delivery of non‑coding RNAs in breast cancer (Review)

Macrina B. Silva‑Cázares, María Z. Saavedra‑Leos, Euclides Jordan‑Alejandre, Stephanie I. Nuñez‑Olvera, Isaac Cómpean‑Martínez, César López‑Camarillo
Pages: 2353-2363
Published online on: 05 October 2020

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Review Open Access

Diverse molecular functions of aspartate β‑hydroxylase in cancer (Review)

Wenqian Zheng, Xiaowei Wang, Jinhui Hu, Bingjun Bai, Hongbo Zhu
Pages: 2364-2372
Published online on: 06 October 2020

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Review Open Access

Glycogen synthase kinase 3β in tumorigenesis and oncotherapy (Review)

Rui He, Suya Du, Tiantian Lei, Xiaofang Xie, Yi Wang
Pages: 2373-2385
Published online on: 20 October 2020

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Review Open Access

Role of RASA1 in cancer: A review and update (Review)

Yanhua Zhang, Yue Li, Quanyue Wang, Bo Su, Hui Xu, Yang Sun, Pei Sun, Rumeng Li, Xiaochun Peng, Jun Cai
Pages: 2386-2396
Published online on: 13 October 2020

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Review

Molecular alterations and clinical relevance in cervical carcinoma and precursors (Review)

Jiayi Sheng, Yi Xiang, Li Shang, Qiongqiong He
Pages: 2397-2405
Published online on: 12 October 2020

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Article Open Access

Protein disulfide isomerase A1 regulates breast cancer cell immunorecognition in a manner dependent on redox state

Rashed Alhammad, Sasiprapa Khunchai, Nopprarat Tongmuang, Thawornchai Limjindaporn, Pa‑Thai Yenchitsomanus, Luciano Mutti, Marija Krstic‑Demonacos, Constantinos Demonacos
Pages: 2406-2418
Published online on: 20 October 2020

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Article Open Access

RP11‑619L19.2 promotes colon cancer development by regulating the miR‑1271‑5p/CD164 axis

Xin‑Wu Zhang, Shun‑Le Li, Di Zhang, Xiao‑Li Sun, Hong‑Jun Zhai
Pages: 2419-2428
Published online on: 07 October 2020

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Article Open Access

Sevoflurane suppresses cell viability and invasion and promotes cell apoptosis in colon cancer by modulating exosome‑mediated circ‑HMGCS1 via the miR‑34a‑5p/SGPP1 axis

Juan He, Huaping Zhao, Xing Liu, Dongmei Wang, Yong Wang, Yanqiu Ai, Jianjun Yang
Pages: 2429-2442
Published online on: 29 September 2020

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Article Open Access

Biological and clinical significance of flap endonuclease‑1 in triple‑negative breast cancer: Support of metastasis and a poor prognosis

Lu Xu, Jing‑Lei Qu, Na Song, Ling‑Yun Zhang, Xue Zeng, Xiao‑Fang Che, Ke‑Zuo Hou, Sha Shi, Zu‑Ying Feng, Xiu‑Juan Qu, Yun‑Peng Liu, Yue‑E Teng
Pages: 2443-2454
Published online on: 16 October 2020

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Article Open Access

Effects of zinc finger protein 403 on the proliferation, migration and invasion abilities of prostate cancer cells

Xintong Xu, Zhihui Zhu, Yipeng Xu, Shasha Tian, Yingjun Jiang, Huajun Zhao
Pages: 2455-2464
Published online on: 01 October 2020

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Article Open Access

Long non‑coding RNA PCAT6 promotes the development of osteosarcoma by increasing MDM2 expression

Xiliang Guan, Yufen Xu, Jufen Zheng
Pages: 2465-2474
Published online on: 16 October 2020

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Article Open Access

BRDT is a novel regulator of eIF4EBP1 in renal cell carcinoma

Pei Wan, Zhilin Chen, Weifeng Zhong, Huiming Jiang, Zhicheng Huang, Dong Peng, Qiang He, Nanhui Chen
Pages: 2475-2486
Published online on: 08 October 2020

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Article Open Access

STARD4 promotes breast cancer cell malignancy

Min Zhang, Zhen Xiang, Feng Wang, Rong Shan, Ling Li, Juan Chen, Bao‑An Liu, Juan Huang, Lun‑Quan Sun, Wei‑Bing Zhou
Pages: 2487-2502
Published online on: 12 October 2020

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Article Open Access

Aberrant methylation‑mediated decrease of lncRNA HNF1A‑AS1 contributes to malignant progression of laryngeal squamous cell carcinoma via EMT

Yewen Shi, Qingqing Zhang, Meng Xie, Yani Feng, Sijing Ma, Chunxi Yi, Zihan Wang, Yanju Li, Xiaohong Liu, Haiqin Liu, Hui Yang, Yan Yan, Yitong Zhang, Xiaoyong Ren, Huanan Luo
Pages: 2503-2516
Published online on: 23 October 2020

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Article Open Access

Anti‑EpCAM monoclonal antibody exerts antitumor activity against oral squamous cell carcinomas

Mika K. Kaneko, Tomokazu Ohishi, Junko Takei, Masato Sano, Takuro Nakamura, Hideki Hosono, Miyuki Yanaka, Teizo Asano, Yusuke Sayama, Hiroyuki Harada, Manabu Kawada, Yukinari Kato
Pages: 2517-2526
Published online on: 13 October 2020

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Article Open Access

Increased hippocampal TrkA expression ameliorates cranial radiation‑induced neurogenesis impairment and cognitive deficit via PI3K/AKT signaling

Shengjun Ji, Haohao Wu, Xin Ding, Qingqing Chen, Xing Jin, Jinming Yu, Ming Yang
Pages: 2527-2536
Published online on: 28 September 2020

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Article Open Access

Anticancer effects of Poncirus fructus on hepatocellular carcinoma through regulation of apoptosis, migration, and invasion

Suvesh Munakarmi, Lokendra Chand, Hyun Beak Shin, Usama Khamis Hussein, Bong‑Sik Yun, Hae Ryong Park, Yeon Jun Jeong
Pages: 2537-2546
Published online on: 05 October 2020

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Article Open Access

High mobility group box 1 induces bone pain associated with bone invasion in a mouse model of advanced head and neck cancer

Tomoya Nakamura, Tatsuo Okui, Kazuaki Hasegawa, Shoji Ryumon, Soichiro Ibaragi, Kisho Ono, Yuki Kunisada, Kyoichi Obata, Masanori Masui, Tsuyoshi Shimo, Akira Sasaki
Pages: 2547-2558
Published online on: 02 October 2020

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Article Open Access

MicroRNA‑138 modulates glioma cell growth, apoptosis and invasion through the suppression of the AKT/mTOR signalling pathway by targeting CREB1

Chi Zhang, Qi Wang, Xiaowen Zhou, Lei Zhang, Ying Yao, Juan Gu, Huairui Chen, Jun Qian, Chun Luo, Qingke Bai, Guohan Hu
Pages: 2559-2568
Published online on: 15 October 2020

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Article Open Access

Transcriptome sequencing analysis reveals unique and shared antitumor effects of three statins in pancreatic cancer

Cheng Chen, Hongjin Wu, Deshengyue Kong, Yu Xu, Zunyue Zhang, Fengrong Chen, Lei Zou, Ziwei Li, Jin Shui, Huayou Luo, Shi‑He Liu, Juehua Yu, Kunhua Wang, F. Charles Brunicardi
Pages: 2569-2580
Published online on: 15 October 2020

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Article Open Access

Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of antagonistic combinations: Implications for future clinical trials in pancreatic cancer

Tanzeel Khan, Alan M. Seddon, Angus G. Dalgleish, Said Khelwatty, Nikolaos Ioannou, Satvinder Mudan, Helmout Modjtahedi
Pages: 2581-2594
Published online on: 22 October 2020

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Article Open Access

Effects and mechanisms of fatty acid metabolism‑mediated glycolysis regulated by betulinic acid‑loaded nanoliposomes in colorectal cancer Retraction in /10.3892/or.2025.8994

Gang Wang, Yang Yu, Yu‑Zhu Wang, Zhi‑Min Zhu, Pei‑Hao Yin, Ke Xu
Pages: 2595-2609
Published online on: 01 October 2020

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Article Open Access

The Hedgehog signaling pathway promotes chemotherapy resistance via multidrug resistance protein 1 in ovarian cancer

Hong Zhang, Lanyan Hu, Minzhang Cheng, Qian Wang, Xinyue Hu, Qi Chen
Pages: 2610-2620
Published online on: 09 October 2020

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Article Open Access

Theabrownin inhibits the cytoskeleton‑dependent cell cycle, migration and invasion of human osteosarcoma cells through NF‑κB pathway‑related mechanisms

Wangdong Jin, Chaoqun Gu, Li Zhou, Xinyu Yang, Mengyuan Gui, Jin Zhang, Jie Chen, Xiaoqiao Dong, Qiang Yuan, Letian Shan
Pages: 2621-2633
Published online on: 12 October 2020

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Article Open Access

Pyrotinib enhances the radiosensitivity of HER2‑overexpressing gastric and breast cancer cells

Tingting Huang, Xiaoxiao Luo, Bili Wu, Ping Peng, Yuhong Dai, Guangyuan Hu, Hong Qiu, Xianglin Yuan
Pages: 2634-2644
Published online on: 21 October 2020

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Article Open Access

lncRNA KTN1‑AS1 promotes glioma cell proliferation and invasion by negatively regulating miR‑505‑3p

Yulong Mu, Qiang Tang, Haiyan Feng, Luwen Zhu, Yan Wang
Pages: 2645-2655
Published online on: 22 October 2020

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Article Open Access

Role and mechanism of FLNa and UCP2 in the development of cervical cancer

Aihong Wang, Lu Liu, Miao Yuan, Sai Han, Xuewu You, Hui Zhang, Fuhua Lei, Youzhong Zhang
Pages: 2656-2668
Published online on: 21 October 2020

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Article Open Access

Radiosensitizing effects of c‑myc gene knockdown‑induced G2/M phase arrest by intrinsic stimuli via the mitochondrial signaling pathway

Yunpeng Fan, Xiaofeng Jia, Tao Xie, Liulong Zhu, Fan He
Pages: 2669-2677
Published online on: 13 October 2020

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Article Open Access

miR‑7/SP1/TP53BP1 axis may play a pivotal role in NSCLC radiosensitivity

Genyan Guo, Lingling Li, Guanchu Song, Jie Wang, Ying Yan, Yuxia Zhao
Pages: 2678-2690
Published online on: 23 October 2020

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Article

MicroRNA‑487b‑3p inhibits osteosarcoma chemoresistance and metastasis by targeting ALDH1A3

Ming Cheng, Ping‑Guo Duan, Zhi‑Zeng Gao, Min Dai
Pages: 2691-2700
Published online on: 19 October 2020

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Article

Arsenic compounds activate the MAPK and caspase pathways to induce apoptosis in OEC‑M1 gingival epidermal carcinoma

Ning‑Ping Foo, Chi‑Lin Ko, Chiao‑Yun Chu, Chia‑Yih Wang, Edmund Cheung So, Bu‑Miin Huang
Pages: 2701-2714
Published online on: 07 October 2020

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Article

Auranofin inhibits the proliferation of lung cancer cells via necrosis and caspase‑dependent apoptosis

Xia Ying Cui, Sun Hyang Park, Woo Hyun Park
Pages: 2715-2724
Published online on: 21 October 2020

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Article

VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells Corrigendum in /10.3892/or.2026.9161

Qilin Wang, Xiangguo Liu
Pages: 2725-2734
Published online on: 05 October 2020

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Article

ARHGAP29 expression may be a novel prognostic factor of cell proliferation and invasion in prostate cancer

Kosuke Shimizu, Hiroaki Matsumoto, Hiroshi Hirata, Koji Ueno, Masahiro Samoto, Junichi Mori, Nakanori Fujii, Yoshihisa Kawai, Ryo Inoue, Yoshiaki Yamamoto, Seiji Yano, Tomoyuki Shimabukuro, Makoto Furutani-Seiki, Hideyasu Matsuyama
Pages: 2735-2745
Published online on: 15 October 2020

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Article

Dracocephalum palmatum Stephan extract induces caspase‑ and mitochondria‑dependent apoptosis via Myc inhibition in diffuse large B cell lymphoma

Jisu Kim, Jeong Nam Kim, Inmyoung Park, Sardana Sivtseva, Zhanna Okhlopkova, Ismayil S. Zulfugarov, Sang‑Woo Kim
Pages: 2746-2756
Published online on: 08 October 2020

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Article

Analysis of the correlation between alterations in N‑glycans and invasiveness in liver cancer cell lines

Hidenori Takahashi, Toshiya Kamiyama, Nozomi Hirane, Nozomi Kobayashi, Takeshi Aiyama, Akihisa Nagatsu, Shingo Shimada, Tatsuya Orimo, Tatsuhiko Kakisaka, Moto Fukai, Hideki Yokoo, Hirofumi Kamachi, Shin‑Ichiro Nishimura, Akinobu Taketomi
Pages: 2757-2769
Published online on: 08 October 2020

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Article

CCL113, a novel sulfonamide, induces selective mitotic arrest and apoptosis in HeLa and HepG2 cells

Ruirong Yi, Yoshifumi Ohno, Zheng Tian, Shuhan Guo, Weiwei Chen, Xue Ma, Nan Nwe Win, Qisen Li, Majid Vahed, Kengo Saito, Shingo Nakamoto, Akiko Suganami, Naohisa Isegawa, Keisuke Yoshida, Shinji Harada, Yutaka Tamura, Atsushi Nishida, Hiroshi Shirasawa
Pages: 2770-2782
Published online on: 13 October 2020

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Article

Propyl gallate reduces the growth of lung cancer cells through caspase‑dependent apoptosis and G1 phase arrest of the cell cycle

Woo Hyun Park
Pages: 2783-2791
Published online on: 20 October 2020

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Retraction Open Access

[Retracted] MicroRNA-375 inhibits glioma cell proliferation and migration by downregulating RWDD3 in vitro

Chen-Xing Ji, Yang-Hua Fan, Fan Xu, Shi-Gang Lv, Min-Hua Ye, Miao-Jing Wu, Xin-Gen Zhu, Lei Wu
Pages: 2792-2792
Published online on: 29 September 2020

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Correction Open Access

[Corrigendum] The specific killing effect of matrine on castration‑resistant prostate cancer cells by targeting the Akt/FoxO3a signaling pathway

Shoumin Bai, Ting Chen, Xiaoli Yu, Ming Luo, Xianju Chen, Chunhao Lin, Yiming Lai, Hai Huang
Pages: 2793-2794
Published online on: 29 September 2020

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Journal Cover
September-2026 Volume 56 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Polyphyllin II inhibits thyroid cancer progression by targeting HRH1 and suppressing Wnt/β‑catenin signaling

Jianwei Sun, Haifeng Liang, Yan Zhang, Ding Ding, Qian Xiang, Mengyang Zheng, Pengyue Zhang
Article Number: 163
Published online on: 23 July 2026

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Review Open Access

Multidimensional molecular mechanisms of drug resistance in breast cancer: Implications for clinical decision‑making and treatment strategies (Review)

Wenya Xu, Shiyao Kang, Shaochen Xin, Yanbin Wu, Yuan Zhao, Miaomiao Sheng
Article Number: 162
Published online on: 22 July 2026

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Review Open Access

XPO1: From basic research to clinical treatment (Review)

Changyan Yang, Jing Zhu, Xiang Zheng, Xiaochen Hou, Jiumei Zhao, Youfu Pan, Yu Tang
Article Number: 161
Published online on: 22 July 2026

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Retraction Open Access

[Retracted] Methylation and intratumoural heterogeneity of 14‑3‑3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Article Number: 160
Published online on: 20 July 2026

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Article Open Access

M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells

Qiang Zhang, Yungang Sun, Yu Zhuang, Shiwei Xu, Mengxu Yao, Siyang Jiao, Qi Wang, Feng Shao, Xiaoying Zhang
Article Number: 159
Published online on: 17 July 2026

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Correction Open Access

[Corrigendum] Emodin attenuated severe acute pancreatitis via the P2X ligand‑gated ion channel 7/NOD‑like receptor protein 3 signaling pathway

Qingkai Zhang, Xufeng Tao, Shilin Xia, Jialin Qu, Huiyi Song, Jianjun Liu, Hailong Li, Dong Shang
Article Number: 158
Published online on: 15 July 2026

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Article Open Access

TM6SF2 overexpression suppresses the proliferation and promotes apoptosis of human hepatocellular carcinoma cells

Ziyou Huai, Wanying Xue, Xinxiao Jin, Shiyu Peng, Wenqiang Xu, Shujing Li, Huanfeng Hao, Yuanyuan Wang
Article Number: 157
Published online on: 14 July 2026

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Correction Open Access

[Corrigendum] VDAC upregulation and αTAT1‑mediated α‑tubulin acetylation contribute to tanespimycin‑induced apoptosis in Calu‑1 cells

Qilin Wang, Xiangguo Liu
Article Number: 156
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Synergistic cytotoxic effects of inorganic phosphate and chemotherapeutic drugs on human osteosarcoma cells

Annamaria Spina, Luca Sorvillo, Emilio Chiosi, Antonietta Esposito, Francesca Di Maiolo, Luigi Sapio, Michele Caraglia, Silvio Naviglio
Article Number: 155
Published online on: 06 July 2026

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Article Open Access

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics

Xinzhen Cai, Yun He, Lili Kang, Dongli Zhou, Mengmeng Wang, Tianyu Ma
Article Number: 154
Published online on: 03 July 2026

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Article

Impact of WFDC2 on the biological functions of cervical cancer cells and the regulation of the ERK/NF‑κB signaling pathway

Yanping Zhang, Hongling Zou, Shufeng Deng, Lvling Zou, Mingzhu Xia, Limin Tao
Article Number: 153
Published online on: 01 July 2026

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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