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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2022 Volume 23 Issue 4

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

NRBP1 negatively regulates SALL4 to reduce the invasion and migration, promote apoptosis and increase the sensitivity to chemotherapy drugs of breast cancer cells

Chao Yang, Xiangmei Zhang, Chao Gao, Kaiye Du, Yunjiang Liu
Article Number: 139
Published online on: 02 March 2022

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Article Open Access

Synergistic inhibition of the growth of MDA‑MB‑231 cells in triple‑negative breast cancer by salinomycin combined with 17‑AAG and its mechanism

Duo He, Bo Wu, Juan Du, Ling Li, Jumei Zhao
Article Number: 138
Published online on: 01 March 2022

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Article Open Access

Immunohistochemical analyses of the expression profiles of INSM1, ATRX, DAXX and DLL3 in solid papillary carcinomas of the breast

Hirotsugu Yanai, Mitsuaki Ishida, Katsuhiro Yoshikawa, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Article Number: 137
Published online on: 01 March 2022

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Article Open Access

TPX2 is a prognostic marker and promotes cell proliferation in neuroblastoma

Yuhki Koike, Chengzeng Yin, Yuki Sato, Yuka Nagano, Akira Yamamoto, Takahito Kitajima, Tadanobu Shimura, Mikio Kawamura, Kohei Matsushita, Yoshinaga Okugawa, Keishiro Amano, Kohei Otake, Yoshiki Okita, Masaki Ohi, Mikihiro Inoue, Keiichi Uchida, Masahiro Hirayama, Yuji Toiyama
Article Number: 136
Published online on: 28 February 2022

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Article Open Access

miR‑148a promotes cell sensitivity through downregulating SOS2 in radiation‑resistant non‑small cell lung cancer cells

Yan Zhang, Xiaoqian Hu
Article Number: 135
Published online on: 24 February 2022

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Article Open Access

PD‑1/PD‑L1 blockade, a novel strategy for targeting metastatic colorectal cancer: A systematic review and meta‑analysis of randomized trials

Maria Saveria Rotundo, Vincenzo Bagnardi, Miryam Rotundo, Mario Comandè, Maria Giulia Zampino
Article Number: 134
Published online on: 23 February 2022

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Review Open Access

Cell‑based immunotherapy of glioblastoma multiforme (Review)

Igor Bryukhovetskiy
Article Number: 133
Published online on: 23 February 2022

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Article

Evaluation of the anti‑proliferative activity of violacein, a natural pigment of bacterial origin, in urinary bladder cancer cell lines

Bruna Neroni, Maria Antonella Zingaropoli, Giulia Radocchia, Maria Rosa Ciardi, Luciana Mosca, Fabrizio Pantanella, Serena Schippa
Article Number: 132
Published online on: 23 February 2022

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Article Open Access

ATIC facilitates cell growth and migration by upregulating Myc expression in lung adenocarcinoma

Niu Niu, Jialong Zeng, Xianni Ke, Wenyu Zheng, Chunmei Fu, Shiqi Lv, Jianghong Fu, Yang Yu
Article Number: 131
Published online on: 23 February 2022

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Article Open Access

Inhibiting mutant KRAS G12D gene expression using novel peptide nucleic acid‑based antisense: A potential new drug candidate for pancreatic cancer

Ayelet Shai, Evleen Galouk, Reem Miari, Hala Tareef, Marei Sammar, Mouhammad Zeidan, Anwar Rayan, Mizied Falah
Article Number: 130
Published online on: 21 February 2022

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Article Open Access

ALW‑II‑41‑27, an EphA2 inhibitor, inhibits proliferation, migration and invasion of cervical cancer cells via inhibition of the RhoA/ROCK pathway

Xiang Li, Dan Li, Rong Ma
Article Number: 129
Published online on: 18 February 2022

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Article Open Access

4‑Acetylantroquinonol B enhances cell death and inhibits autophagy by downregulating the PI3K/Akt/MDR1 pathway in gemcitabine‑resistant pancreatic cancer cells

Ying-Yin Chen, Sheng-Yi Chen, Tsung-Ju Li, Ting-Wei Lin, Chin-Chu Chen, Gow-Chin Yen
Article Number: 128
Published online on: 18 February 2022

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Article Open Access

Prognostic significance of adipophilin expression in biopsy specimens of patients with triple‑negative breast cancer

Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Article Number: 127
Published online on: 18 February 2022

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Article

Survival outcomes of non‑definitive therapy for muscle‑invasive bladder cancer

Kiyoaki Nishihara, Kosuke Ueda, Hirofumi Kurose, Naoyuki Ogasawara, Tasuku Hiroshige, Katsuaki Chikui, Kazuhisa Ejima, Keiichiro Uemura, Makoto Nakiri, Shigetaka Suekane, Tsukasa Igawa
Article Number: 126
Published online on: 17 February 2022

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Article Open Access

Association and mechanism of garlic consumption with gastrointestinal cancer risk: A systematic review and meta‑analysis

Yangyang Wang, Ping Huang, Yufei Wu, Duanrui Liu, Mingyu Ji, Huanjie Li, Yunshan Wang
Article Number: 125
Published online on: 17 February 2022

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Review Open Access

Anticoagulation for atrial fibrillation in active cancer (Review)

Dimitrios Farmakis, Pavlos Papakotoulas, Eleni Angelopoulou, Theodoros Bischiniotis, George Giannakoulas, Panagiotis Kliridis, Dimitrios Richter, Ioannis Paraskevaidis
Article Number: 124
Published online on: 17 February 2022

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Article Open Access

Selective radiosensitization by nitazoxanide of quiescent clonogenic colon cancer tumour cells

Henning Karlsson, Mårten Fryknäs, Wojciech Senkowski, Rolf Larsson, Peter Nygren
Article Number: 123
Published online on: 17 February 2022

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Article

Overexpression of hepatocyte growth factor protects chronic myeloid leukemia cells from apoptosis induced by etoposide

Xiaojiao Zheng, Shixuan Hua, Hang Zhao, Zhou Gao, Dong Cen
Article Number: 122
Published online on: 15 February 2022

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Review Open Access

Research progress on RNA‑binding proteins in breast cancer (Review)

Wenzhu Zhang, Linlin Liu, Shengdi Zhao, Liang Chen, Yuxian Wei, Wenlin Chen, Fei Ge
Article Number: 121
Published online on: 14 February 2022

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Article Open Access

Biological response of adrenal carcinoma and melanoma cells to mitotane treatment

Ewelina Stelcer, Hanna Komarowska, Karol Jopek, Agnieszka Żok, Dariusz Iżycki, Agnieszka Malińska, Beata Szczepaniak, Zhanat Komekbai, Marek Karczewski, Tomasz Wierzbicki, Wiktoria Maria Suchorska, Marek Ruchała, Marcin Ruciński
Article Number: 120
Published online on: 10 February 2022

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Review Open Access

Lipid metabolism of cancer stem cells (Review)

Huihui Liu, Zhengyang Zhang, Lian Song, Jie Gao, Yanfang Liu
Article Number: 119
Published online on: 09 February 2022

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Article Open Access

Importance of multigene panel test in patients with consanguineous marriage and family history of breast cancer

Vahit Ozmen, Ahmet Okay Caglayan, Kanay Yararbas, Cetin Ordu, Fatma Aktepe, Tolga Ozmen, Ahmet Serkan Ilgun, Gursel Soybir, Gul Alco, Georgios N. Tsaousis, Eirini Papadopoulou, Konstantinos Agiannitopoulos, Georgia Pepe, Stavroula Kampouri, George Nasioulas, Efe Sezgin, Atilla Soran
Article Number: 118
Published online on: 09 February 2022

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Article Open Access

PCDHB15 as a potential tumor suppressor and epigenetic biomarker for breast cancer

Ching-Chung Chiang, Guan-Ling Lin, Shu-Yi Yang, Chi-Wen Tu, Wen-Long Huang, Chun-Feng Wei, Feng-Chi Wang, Pin-Ju Lin, Wan-Hong Huang, Yu-Ming Chuang, Yu-Ting Lee, Chia-Chou Yeh, Michael W.Y. Chan, Yu-Chen Hsu
Article Number: 117
Published online on: 09 February 2022

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Article Open Access

Effects of 2,2',4'‑trihydroxychalcone on the proliferation, metastasis and apoptosis of A549 human lung cancer cells

Jia-Lin Sun, Zhan-Qi Cao, Shi-Wei Sun, Zhong-Hua Sun, Shu-Hong Sun, Jin-Feng Ye, Ping Leng
Article Number: 116
Published online on: 09 February 2022

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Article Open Access

Prophylaxis of cancer‑associated venous thromboembolism with low‑molecular‑weight heparin‑tinzaparin: Real world evidence

Athina Christopoulou, Alexandros Ardavanis, Christos Papandreou, Georgios Koumakis, Georgios Papatsimpas, Pavlos Papakotoulas, Nikolaos Tsoukalas, Charalambos Andreadis, Georgios Samelis, Pavlos Papakostas, Gerasimos Aravantinos, Nikolaos Ziras, Maria Souggleri, Charalambos Kalofonos, Epameinondas Samantas, Paris Makrantonakis, Georgios Pentheroudakis, Athanasios Athanasiadis, Helen Stergiou, Alexandros Bokas, Anastasios Grivas, Elli-Sofia Tripodaki, Ioannis Varthalitis, Eleni Timotheadou, Ioannis Boukovinas
Article Number: 115
Published online on: 09 February 2022

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Article Open Access

Clinical feasibility of modified procarbazine and lomustine chemotherapy without vincristine as a salvage treatment for recurrent adult glioma

Stephen Ahn, Young Il Kim, Ja Young Shin, Jae-Sung Park, Changyoung Yoo, Youn Soo Lee, Yong-Kil Hong, Sin-Soo Jeun, Seung Ho Yang
Article Number: 114
Published online on: 09 February 2022

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Review Open Access

Cervical cancer, geographical inequalities, prevention and barriers in resource depleted countries (Review)

Anna Bogdanova, Charles Andrawos, Constantina Constantinou
Article Number: 113
Published online on: 09 February 2022

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Article Open Access

KIF18B promotes breast cancer cell proliferation, migration and invasion by targeting TRIP13 and activating the Wnt/β‑catenin signaling pathway

Lan Liu, Zhaofeng Zhang, Xiulin Xia, Jing Lei
Article Number: 112
Published online on: 08 February 2022

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Article Open Access

Potential of a sphingosine 1‑phosphate receptor antagonist and sphingosine kinase inhibitors as targets for multiple myeloma treatment

Yuko Tanaka, Seiichi Okabe, Kazuma Ohyashiki, Akihiko Gotoh
Article Number: 111
Published online on: 08 February 2022

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Article Open Access

Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivo

Fan Zhang, Hua Zhang, Wenjun Qian, Yuyan Xi, Lihua Chang, Xiaoling Wu, Mu Li
Article Number: 110
Published online on: 07 February 2022

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Review

Role and mechanism of action of LAPTM4B in EGFR‑mediated autophagy (Review)

Xiaokun Ji, Hua Ma, Yun Du
Article Number: 109
Published online on: 07 February 2022

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Review

Transient receptor potential channels in multiple myeloma (Review)

Lingjun Meng, Guiying Gu, Lintao Bi
Article Number: 108
Published online on: 07 February 2022

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Retraction Open Access

[Retracted] Conversion of epithelial‑to‑mesenchymal transition to mesenchymal‑to‑epithelial transition is mediated by oxygen concentration in pancreatic cancer cells

Shuo Chen, Xi Chen, Wei Li, Tao Shan, Wan Run Lin, Jiancang Ma, Xijuan Cui, Wenbin Yang, Gang Cao, Yiming Li, Li Wang, Ya'an Kang
Article Number: 107
Published online on: 04 February 2022

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Article

PI3K/Akt/YAP signaling promotes migration and invasion of DLD‑1 colorectal cancer cells

Tomoya Takeda, Yuuta Yamamoto, Masanobu Tsubaki, Takuya Matsuda, Akihiro Kimura, Natsumi Shimo, Shozo Nishida
Article Number: 106
Published online on: 03 February 2022

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Article Open Access

Evaluation of the expression of fatty acid synthase and O‑GlcNAc transferase in patients with liver cancer by exploration of transcriptome databases and experimental approaches

Sadia Raab, Ninon Very, Belinda Duchêne, Pierre Rybarczyk, Nicolas Jonckheere, Ikram El Yazidi‑Belkoura, Tony Lefebvre
Article Number: 105
Published online on: 03 February 2022

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Journal Cover
November-2026 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Ivonescimab combined with radiotherapy in the treatment of advanced lung adenocarcinoma with high expression of PD‑L1: A case report

Qi Zhou, Bo Yang, Hongyi Cai, Jun Jiang, Rong Chen
Article Number: 538
Published online on: 02 October 2026

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Article Open Access

Association between antidepressant exposure and prognosis in breast cancer: A systematic review and meta‑analysis

Qisong Chen, Yihan Shen, Xiaoming Zhang, Ting Jiang, Shiyan Zhang, Xinyan Yu, Feng Hong
Article Number: 537
Published online on: 02 October 2026

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Review Open Access

Brain‑derived neurotrophic factor in solid tumor angiogenesis and neurovascular‑immune interactions (Review)

Guoqing Zhu, Dianliang Zhang, Hao Wang, Sen Yan, Mingchao Ni, Shangkun Ning, Chong Wang, Mei Liu, Jibing Liu
Article Number: 536
Published online on: 01 October 2026

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Article Open Access

hnRNPC promotes oral squamous cell carcinoma progression via N6‑methyladenosine‑dependent stabilization of BCAT1 to enhance branched‑chain amino acid metabolism

Zhixin Zhang, Xin Gao, Ting Han, Fei Chai, Menghui Gao, Yulin An
Article Number: 535
Published online on: 01 October 2026

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Expression of Concern Open Access

[Expression of Concern] Reduced migration of Ishikawa cells associated with downregulation of aquaporin‑5

Xiu Xiu Jiang, Kai Hong Xu, Jun Yan Ma, Yong Hong Tian, Xiao Yan Guo, Jun Lin, Rui Jin Wu
Article Number: 534
Published online on: 30 September 2026

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Case Report Open Access

A thoracic SMARCA4‑deficient undifferentiated tumor: A case report

Xiaocheng Wang, Miao Chen, Mingzhe Wang, Chengjun Ban, Lishan Zhang, Heng Zou, Hongwu Wang, Bing Yang
Article Number: 533
Published online on: 29 September 2026

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Case Report Open Access

Stage IIIB pulmonary sarcomatoid carcinoma treated with spatially fractionated radiotherapy combined with antiangiogenic therapy and sequential chemo‑immunotherapy: A case report

Zijian Qiu, Feng Xuan, Xi Mao, Peipei Yang, Xiaoping Zhu
Article Number: 532
Published online on: 29 September 2026

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Article Open Access

Single‑cell transcriptomics identifies PRDX1 and GPX4 as potential ferroptosis regulators and tumor microenvironment‑­related molecules in hepatocellular carcinoma

Zhou Zhang, Hui Chen, Chen Qian, Ningning Yang, Zijing Liu, Ruirui Yang
Article Number: 531
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] Interferon‑α suppresses invasion and enhances cisplatin‑mediated apoptosis and autophagy in human osteosarcoma cells

Jun Zhao, Mingli Wang, Zeng Li, Jingxian Chen, Zongshen Yin, Jun Chang, Dongmei Gao, Shiping Wang
Article Number: 530
Published online on: 28 September 2026

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Article Open Access

KRT14 activated by transcription factor E2F1 promotes bladder cancer progression

Xingheng Chen, Sinan Liu, Xiaosong Zhang, Xiang Chen, Chenlu Wang
Article Number: 529
Published online on: 24 September 2026

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Review Open Access

Research progress of pancreatic cancer based on ferroptosis‑cuproptosis interaction (Review)

Wenqing Liu, Minglu Ding, Ruijiao Ji, Zhenmin Qiao, Ran Liu, Peijian Chen, Lantao Liu
Article Number: 528
Published online on: 24 September 2026

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Correction Open Access

[Corrigendum] Decreased expression of CD63 tetraspanin protein predicts elevated malignant potential in human esophageal cancer

Xiaojing Lai, Qing Gu, Xia Zhou, Wei Feng, Xiao Lin, Yan He, Jinming Cao, Pengfei Liu, Huojun Zhang, Xiao Zheng
Article Number: 527
Published online on: 24 September 2026

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Case Report Open Access

Therapy‑related acute myeloid leukemia with a rare complex karyotype following first‑line therapy for small cell lung cancer: A case report

Lin Luo, Sha Yu
Article Number: 526
Published online on: 23 September 2026

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Article Open Access

Netupitant‑palonosetron combined with dexamethasone for preventing chemotherapy‑induced nausea and vomiting in high‑risk patients with colorectal cancer receiving moderately emetogenic chemotherapy: A retrospective study

Jiwen Fan, Wenjuan Lai, Boran Cheng, Meijing Chen, Jing Gao, Shubin Wang, Gangling Tong
Article Number: 525
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] Upregulation of H19 promotes invasion and induces epithelial‑to‑mesenchymal transition in esophageal cancer

Cheng Huang, Lihua Cao, Limin Qiu, Xiaoli Dai, Linwei Ma, Yingting Zhou, Huifen Li, Min Gao, Weiyong Li, Qing Zhang, Koulan Han, Hongzhen Lv
Article Number: 524
Published online on: 23 September 2026

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Article Open Access

Pan‑cancer prognostic value of TGFBR1: Bioinformatics and experimental validation with a focus on gastric cancer

Xia Zhao, Lufan Shen, Zhiyuan Gong, Mengwen Lv, Yan Zhang, Bingxi Tang, Xinli Li
Article Number: 523
Published online on: 21 September 2026

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Article Open Access

MAD2L1 overexpression promotes breast cancer progression and confers resistance to paclitaxel via proteasomal stabilization

Shih-Ho Wang, Cheng-Hsi Yeh, Chia-Wei Wu, Chia-Yi Hsu, Eing-Mei Tsai, Chao-Ming Hung, Ming-Wei Lin, Tsung-Hua Hsieh
Article Number: 522
Published online on: 21 September 2026

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Article Open Access

Efficacy of circulating tumour DNA in guiding postoperative adjuvant chemotherapy for resectable colorectal cancer: A meta‑analysis based on cohort studies

Jiale Ruan, Wen Shi, Wenwen Shi, Xinyan Zhang, Yixia Chen, Xiaoling Feng, Jian Song
Article Number: 521
Published online on: 21 September 2026

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Article Open Access

Clinicopathological role of microRNA‑205, microRNA‑223 and microRNA‑590 in vulvar cancer

Edyta Leśniak, Emilia Stec-Martyna, Bartłomiej Tomasik, Hanna Romanowicz, Oliwia Maciejewska, Jan Bieńkiewicz, Andrzej Malinowski, Miłosz Wilczyński
Article Number: 520
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 519
Published online on: 21 September 2026

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Article Open Access

Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Case Report Open Access

Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Article Open Access

Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Article Open Access

Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Article Open Access

Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Review Open Access

Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Article Open Access

Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Article Open Access

Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Review Open Access

Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara-Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Article Open Access

Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Review Open Access

Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Article

Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Review Open Access

Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Article

Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum-Quiroz, Noemí García-Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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December-2026 Volume 32 Issue 6

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Shikonin combined with curcumin synergistically induces apoptosis of glioma cells by inhibiting the PI3K/Akt/NF‑κB signaling pathway

Xiaojin Zhao, Mingwen Zhang, Yongchao He, Zhihu Yu, Yichun Sun, Jiabin Zhu
Article Number: 564
Published online on: 23 October 2026

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MicroRNA‑155‑5p‑dependent upregulation of PDCD4 is involved in oridonin‑induced proliferation inhibition of leukemia cells

Hui Ding, Min Fang, Qingqing Yang, Chaozhe Wang, Yunhua Wu, Xidi Wang, Guosheng Jiang, Kehong Bi
Article Number: 563
Published online on: 23 October 2026

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Five‑fraction stereotactic body radiotherapy for prostate cancer in octogenarians and nonagenarians: A single‑institution retrospective cohort study

Atsuto Katano, Hideomi Yamashita
Article Number: 562
Published online on: 22 October 2026

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Article Open Access

Identification of SLC7A5 and transferrin as key ferroptosis modulators in triple‑negative breast cancer

Ruidi Liu, Xiao Cui, Bingyu Guo, Yiting Liu, Feng Lin, Zhiqiang Fu, Bing Xie
Article Number: 561
Published online on: 22 October 2026

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PEG10/TRIB3 axis is associated with malignant behavior and Notch‑related signaling in oral squamous cell carcinoma cells

Jing Zhang, Ying Liu
Article Number: 560
Published online on: 22 October 2026

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Article Open Access

Diagnostic performance of a combined TAP, TAM, CA125 and CA153 panel for stage I breast cancer in patients with unilateral nipple discharge

Yingli Men, Ruiting Feng, Beibei Ye, Yahui Hu, Ping Wang, Jizhi Zhao, Yang Zheng, Hui Wang, Yinsen Song, Cong Ding
Article Number: 559
Published online on: 22 October 2026

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Correction Open Access

[Corrigendum] Individualized therapy based on the combination of mini‑PDX and NGS for a patient with metastatic AFP‑producing and HER‑2 amplified gastric cancer

Xiaodan Zhu, Xiaoqing Xu, Baonan Zhang, Yun Dong, Shixia Gong, Tingjie Gong, Feifei Zhang, Chunhui Jin
Article Number: 558
Published online on: 21 October 2026

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Article Open Access

Calycosin synergistically promotes ferroptosis in cervical cancer cells by inducing epithelial‑mesenchymal transition

Lei Zhang, Qiuyi Shen, Jingyi Zhu, Ping Wang, Wanhong Wei, Jie Zhou
Article Number: 557
Published online on: 19 October 2026

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Correction Open Access

[Corrigendum] Androgen deprivation therapy has no effect on Pim‑1 expression in a mouse model of prostate cancer

Jiang Wang, Gang Li, Bo Li, Hualin Song, Zhiqun Shang, Ning Jiang, Yuanjie Niu
Article Number: 556
Published online on: 19 October 2026

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Article Open Access

An interpretable machine‑learning model to predict moderate‑to‑severe acute radiation esophagitis following regional nodal irradiation for breast cancer

Bin He, Zhongchun Qi, Hengdi Zhang, Linling Li, Hua Li, Xinyun Zou, Yu Tan, Ling Zhang, Fangyuan Kong
Article Number: 555
Published online on: 16 October 2026

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Anti‑neoplastic effects of Chrysanthemum indicum extract on a human hypopharyngeal squamous cell carcinoma cell line 

Ching-Wen Liu, Li-Ching Chang, Ting-Ting Lai, Hsiao-Chi Lai
Article Number: 554
Published online on: 16 October 2026

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Article Open Access

KAZALD1 upregulation predicts poor prognosis in epithelial ovarian cancer: Clinical validation and immune correlates

Ruru Zhao, Ye Hu, Jia Wang, Jingjing Lu, Guiqiang Du
Article Number: 553
Published online on: 15 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic effect of jolkinolide B and the mechanism of activity in breast cancer MDA‑MB‑231 cells

Chao Sun, Hongxia Cui, Hongyan Yang, Xiaohui Du, Liling Yue, Jicheng Liu, Yu Lin
Article Number: 552
Published online on: 14 October 2026

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Article Open Access

Optimal timing of thoracic radiotherapy with osimertinib in unresectable EGFR‑mutant non‑small cell lung cancer

Mengting Lai, Yanhua Zhou, Weili Yi, Jian Huang, Zhili Chen, Xin Yin, Li Qin, Dongning Huang
Article Number: 551
Published online on: 13 October 2026

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Article Open Access

Unveiling a dual‑pathway prognostic model: Integrating T cell‑related and ubiquitination‑related genes in lung adenocarcinoma

Shuang Zeng, Huidi Gao, Hongying Liang, Degang Zhang
Article Number: 550
Published online on: 13 October 2026

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Article Open Access

Supplementary value of primary tumor volume for prognostic stratification in patients with T3‑4 nasopharyngeal carcinoma: A retrospective cohort study

Hui Huang, Yusong Lu, Yingjie Ouyang, Min Pan, Xinyu Tang, Hongrui He, Tingfeng Zhang, Qi Gong, Chunqiao Chen, Qiuqiu Chen
Article Number: 549
Published online on: 13 October 2026

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Safety of concurrent immune checkpoint inhibitor therapy during postoperative radiotherapy for triple‑negative breast cancer: A preliminary retrospective analysis

Gai Liang, Qu Zhang, Mengting Yuan, Guojun Yao, Feng Yuan
Article Number: 548
Published online on: 13 October 2026

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Expression of Concern Open Access

[Expression of Concern] Expression of L1 protein correlates with cluster of differentiation 24 and integrin β1 expression in gastrointestinal stromal tumors

Yue Du, Haihong Zhang, Zhongmin Jiang, Guowei Huang, Wenli Lu, Hesheng Wang
Article Number: 547
Published online on: 12 October 2026

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Article Open Access

Bulk and single‑cell analysis of FAM72D reveals its prognostic and functional relevance in hepatocellular carcinoma

Cuihao Zhao, Quliyang Yin, Jianfeng Yu, Weiqi Duan, Yufeng Li, Qian Jian
Article Number: 546
Published online on: 12 October 2026

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Article Open Access

Serum metabolomic signatures associated with gastric signet‑ring cell carcinoma: A dual‑platform mass spectrometry study

Huiling Cao, Shuwei Guo, Jinchang Li, Yuying Bian, Jianjiang Shen, Jia Wang, Fei Meng, Wenlu Sun, Qingmin Sun, Wanjian Gu
Article Number: 545
Published online on: 09 October 2026

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Case Report Open Access

Drug‑eluting bead transarterial chemoembolization with immunotherapy and targeted therapy for advanced clear cell renal cell carcinoma: A case report

Yin Gao, Qiang Xu, Dongxu Kang, Longzhen Piao
Article Number: 544
Published online on: 08 October 2026

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Case Report Open Access

Unexpected favorable response of stage IV gastric adenocarcinoma to sintilimab combined with chemotherapy: A case report

Jian Han, Zhe Zhu, Liang Huang, Liang Zhuang, Lihong Zhang, Yixin Tong, Chao Zhang, Hanlin Mu, Huaping Xie
Article Number: 543
Published online on: 08 October 2026

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Correction Open Access

[Corrigendum] Overexpression of microRNA-96-5p inhibits autophagy and apoptosis and enhances the proliferation, migration and invasiveness of human breast cancer cells

Yawei Shi, Yang Zhao, Nan Shao, Runyi Ye, Yin Lin, Ning Zhang, Wen Li, Yunjian Zhang, Shenming Wang
Article Number: 542
Published online on: 08 October 2026

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Article Open Access

Potential of clinical staging for long‑term prognosis prediction in pathological stage III gastric cancer

Naosuke Nakamichi, Hiroyuki Inoue, Takeshi Kubota, Toshiyuki Kosuga, Keiji Nishibeppu, Kazuya Takabatake, Shutaro Sumiyoshi, Junichi Hamada, Kento Kurashima, Hidemasa Kubo, Jun Kiuchi, Taisuke Imamura, Kenji Nanishi, Hiroki Shimizu, Tomohiro Arita, Yusuke Yamamoto, Hirotaka Konishi, Ryo Morimura, Hitoshi Fujiwara, Toshiya Ochiai, Atsushi Shiozaki
Article Number: 541
Published online on: 07 October 2026

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Article Open Access

NOL11 is a novel prognostic biomarker associated with immune infiltration and tumor progression in hepatocellular carcinoma

Hong Xie, Shengnan Wang, Xiaoyan Sheng, Lei Ye
Article Number: 540
Published online on: 07 October 2026

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Correction Open Access

[Corrigendum] Emodin induces apoptosis of human breast cancer cells by modulating the expression of apoptosis‑related genes

Cong Zu, Mingdi Zhang, Hui Xue, Xiaopeng Cai, Lei Zhao, Anning He, Guangyuan Qin, Chunshu Yang, Xinyu Zheng
Article Number: 539
Published online on: 02 October 2026

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