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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2014 Volume 32 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Antibody therapies for melanoma: New and emerging opportunities to activate immunity (Review)

Sadek Malas, Micaela Harrasser, Katie E. Lacy, Sophia N. Karagiannis
Pages: 875-886
Published online on: 20 June 2014

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Article Open Access

Impact of 5-fluorouracil metabolizing enzymes on chemotherapy in patients with resectable colorectal cancer

Takumi Ochiai, Masahiko Umeki, Hiroshi Miyake, Tatsumi Iida, Minoru Okumura, Kazuhide Ohno, Masashi Sakamoto, Nobukazu Miyoshi, Masahiko Takahashi, Hidenori Tsumura, Yukihiko Tokunaga, Haruhiko Naitou, Takuji Fukui
Pages: 887-892
Published online on: 02 July 2014

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Article Open Access

IGF expression in HPV-related and HPV-unrelated human cancer cells

Julia Durzyńska, Elisabeth Barton
Pages: 893-900
Published online on: 11 July 2014

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Article Open Access

Aurora kinase A is a possible target of OSU‑03012 to destabilize MYC family proteins

Andres Silva, Jennie Wang, Sarah Lomahan, Tuan-Anh Tran, Laura Grenlin, Akiko Suganami, Yutaka Tamura, Naohiko Ikegaki
Pages: 901-905
Published online on: 11 July 2014

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Article Open Access

Loss of 11p11 is a frequent and early event in sporadic nonfunctioning pancreatic neuroendocrine neoplasms

Sven-Petter Haugvik, Ludmila Gorunova, Lisbeth Haugom, Anne  Mette Eibak, Ivar Prydz Gladhaug, Sverre Heim, Francesca Micci
Pages: 906-912
Published online on: 11 July 2014

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Article Open Access

GPC3 expression in mouse ovarian cancer induces GPC3‑specific T cell-mediated immune response through M1 macrophages and suppresses tumor growth

Chenhong Luo, Kiyosumi Shibata, Shiro Suzuki, Hiroaki Kajiyama, Takeshi  Senga, Yoshihiro Koya, Mina Daimon, Mamoru Yamashita, Fumitaka Kikkawa
Pages: 913-921
Published online on: 02 July 2014

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Article

New enhanced and effective method for staging cancer to detect lymph nodes after fat-dissociation

Shiki Fujino, Norikatsu Miyoshi, Masayuki  Ohue, Shingo  Noura, Yasuhiko  Tomita, Masahiko  Yano, Masato Sakon
Pages: 922-926
Published online on: 09 July 2014

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Article

Altered expression of ETV1 and its contribution to tumorigenic phenotypes in gastrointestinal stromal tumors

Yan Zhang, Meng-Li Gu, Xin-Xin  Zhou, Han  Ma, Hang-Ping  Yao, Feng Ji
Pages: 927-934
Published online on: 23 June 2014

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Article

Upregulation of autophagy by hypoxia-inducible factor-1α promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia

Haitao Zhu, Dongqing  Wang, Lirong  Zhang, Xiaodong  Xie, Yingying  Wu, Yanfang  Liu, Genbao  Shao, Zhaoliang  Su
Pages: 935-942
Published online on: 02 July 2014

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Article

An ovarian cancer model with positive ER: Reversion of ER antagonist resistance by Src blockade

Long Li, Xiaojun Li, Xiaobing Han, Ting Yang, Jing  Fu, Yunfeng Zhang, Wenli Gou
Pages: 943-950
Published online on: 23 June 2014

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Article

Downregulation of microRNA-155 accelerates cell growth and invasion by targeting c-myc in human gastric carcinoma cells

Shibo Sun, Peng  Sun, Chunmei  Wang, Tiewei  Sun
Pages: 951-956
Published online on: 24 June 2014

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Article

miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma

Xiaoling She, Zhibin Yu, Yulong Cui, Qianqian Lei, Zeyou Wang, Gang Xu, Juanjuan Xiang, Minghua Wu, Guiyuan Li
Pages: 957-964
Published online on: 10 July 2014

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Article

Knockdown of CXCR7 inhibits proliferation and invasion of osteosarcoma cells through inhibition of the PI3K/Akt and β-arrestin pathways

Yong Zhang, Chao-Qun Yang, Yang  Gao, Ce  Wang, Cheng-Lin Zhang, Xu-Hui Zhou
Pages: 965-972
Published online on: 25 June 2014

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Article

Anti-apoptotic and apoptotic pathway analysis of arsenic trioxide‑induced apoptosis in human gastric cancer SGC-7901 cells

Yao Yu, Yu Yang, Jing Wang
Pages: 973-978
Published online on: 20 June 2014

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Article

Downregulation of HNF1 homeobox B is associated with drug resistance in ovarian cancer

Jianchao Li, Yonghong Zhang, Yutao  Gao, Yuqian  Cui, Hua Liu, Mi Li, Yongjie  Tian
Pages: 979-988
Published online on: 27 June 2014

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Article

Expression of the adaptor protein Tks5 in human cancer: Prognostic potential

Stanley S. Stylli, Rodney B. Luwor, Andrew H. Kaye, Stacey  T.T. I, Christopher M. Hovens, Peter  Lock
Pages: 989-1002
Published online on: 04 July 2014

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Article

Expression of miR-224-5p is associated with the original cisplatin resistance of ovarian papillary serous carcinoma

Henan Zhao, Tie Bi, Zhenyun Qu, Jiyong  Jiang, Shiying  Cui, Yan Wang
Pages: 1003-1012
Published online on: 07 July 2014

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Article

Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells

Yunyuan Zhang, Xian Chen, Min Qiao, Bing-Qiang Zhang, Ning Wang, Zhonglin Zhang, Zhan Liao, Liyi Zeng, Youlin Deng, Fang Deng, Junhui Zhang, Liangjun Yin, Wei Liu, Qian Zhang, Zhengjian Ya, Jixing Ye, Zhongliang Wang, Lan Zhou, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, Hongyu Zhang
Pages: 1013-1020
Published online on: 03 July 2014

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Article

MicroRNA-451 regulates activating transcription factor 2 expression and inhibits liver cancer cell migration

Guixiang Lv, Zheng Hu, Yi Tie, Jingli Du, Hanjiang Fu, Xu Gao, Xiaofei Zheng
Pages: 1021-1028
Published online on: 27 June 2014

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Article

MicroRNA-1290 promotes asiatic acid‑induced apoptosis by decreasing BCL2 protein level in A549 non‑small cell lung carcinoma cells

Ki Bbeum Kim, Karam Kim, Seunghee Bae, Yeonghmin Choi, Hwa Jun Cha, Soo Yeon Kim, Jae Ho Lee, So Hyeon Jeon, Ho Jung Jung, Kyu Joong Ahn, In-Sook An, Sungkwan An
Pages: 1029-1036
Published online on: 10 July 2014

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Article

Ligustrum lucidum Ait. fruit extract induces apoptosis and cell senescence in human hepatocellular carcinoma cells through upregulation of p21

Bing Hu, Qin Du, Shan Deng, Hong-Mei  An, Chuan-Fang  Pan, Ke‑Ping  Shen, Ling  Xu, Meng-Meng Wei, Shuang-Shuang Wang
Pages: 1037-1042
Published online on: 07 July 2014

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Article

Expression of neighbor of Punc E11 in hepatocarcinogenesis induced by diethylnitrosamine

Young Hee Kim, Kyung A Kwak, Jin Seok Kang
Pages: 1043-1049
Published online on: 23 June 2014

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Article

Lin28/let-7/Bcl-xL pathway: The underlying mechanism of drug resistance in Hep3B cells

Nan Tian, Ziwu Han, Zhaohui Li, Mingjie  Zhou, Chunlei  Fan
Pages: 1050-1056
Published online on: 25 June 2014

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Article

Vitamin C enhances anticancer activity in methotrexate‑treated Hep3B hepatocellular carcinoma cells

Giou-Teng Yiang, Pei-Lun Chou, Yu-Ting Hung, Jen-Ni Chen, Wei-Jung Chang, Yung-Luen Yu, Chyou-Wei Wei
Pages: 1057-1063
Published online on: 25 June 2014

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Article

Effect of the downregulation of SMYD3 expression by RNAi on RIZ1 expression and proliferation of esophageal squamous cell carcinoma

Shang-Wen Dong, Hao Zhang, Bao-Li  Wang, Pei  Sun, Yuan-Guo  Wang, Peng Zhang
Pages: 1064-1070
Published online on: 03 July 2014

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Article

ZNF703 promotes tumor cell proliferation and invasion and predicts poor prognosis in patients with colorectal cancer

Feng Ma, Lihong Bi, Gongli Yang, Mengnan Zhang, Cuiping Liu, Yingying Zhao, Yadong Wang, Jide Wang, Yang Bai, Yali Zhang
Pages: 1071-1077
Published online on: 07 July 2014

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Article

Identification of ApoA1, HPX and POTEE genes by omic analysis in breast cancer

Naci Cine, Ahmet Tarik Baykal, Deniz Sunnetci, Zafer  Canturk, Muge  Serhatli, Hakan  Savli
Pages: 1078-1086
Published online on: 23 June 2014

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Article

Matrine induces the apoptosis of lung cancer cells through downregulation of inhibitor of apoptosis proteins and the Akt signaling pathway

Huiyan Niu, Yifei Zhang, Baogang Wu, Yi Zhang, Hongfang Jiang, Ping He
Pages: 1087-1093
Published online on: 20 June 2014

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Article

Artemisinin reduces cell proliferation and induces apoptosis in neuroblastoma

Shunqin Zhu, Wanhong Liu, Xiaoxue Ke, Jifu Li, Renjian Hu, Hongjuan Cui, Guanbin Song
Pages: 1094-1100
Published online on: 11 July 2014

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Article

Aberrant expression of enhancer of zeste homologue 2, correlated with HIF-1α, refines relapse risk and predicts poor outcome for breast cancer

Min Dong, Xin-Juan Fan, Zhan-Hong Chen, Tian-Tian Wang, Xing Li, Jie  Chen, Qu Lin, Jing-Yun Wen, Xiao-Kun Ma, Li Wei, Dan-Yun Ruan, Ze-Xiao Lin, Quentin Liu, Xiang-Yuan Wu, Xiang-Bo Wan
Pages: 1101-1107
Published online on: 10 July 2014

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Article

Effect of DJ-1 overexpression on the proliferation, apoptosis, invasion and migration of laryngeal squamous cell carcinoma SNU-46 cells through PI3K/AKT/mTOR

Bin Wang, Hao Qin, Yuejian  Wang, Weixiong  Chen, Jie  Luo, Xiaolin Zhu, Weiping  Wen, Wenbin Lei
Pages: 1108-1116
Published online on: 24 June 2014

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Article

Tussilago farfara L. augments TRAIL-induced apoptosis through MKK7/JNK activation by inhibition of MKK7‑TIPRL in human hepatocellular carcinoma cells

Hyo-Jung Lee, Hyun-Soo Cho, Soo  Young Jun, Jeong-Ju  Lee, Ji‑Yong  Yoon, Jae-Hye  Lee, Hyuk‑Hwan Song, Sang  Ho Choi, Soo‑Yong  Kim, Vassiliki Saloura, Choon  Gil Park, Nam-Soon Kim
Pages: 1117-1123
Published online on: 23 June 2014

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Article

S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-β signaling pathway in cancer cells

Dandan Tong, Hui Qu, Xiangning Meng, Yang Jiang, Duanyang Liu, Shengqian Ye, He Chen, Yan Jin, Songbin Fu, Jingshu Geng
Pages: 1124-1132
Published online on: 26 June 2014

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Article

Establishment and characterization of a cisplatin‑resistant human osteosarcoma cell line

Tao Han, Xiaoming Zhu, Julei Wang, Haien Zhao, Qiong Ma, Jian Zhao, Xiuchun Qiu, Qingyu Fan
Pages: 1133-1139
Published online on: 07 July 2014

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Article

Cyclooxygenase-2 inhibition as a strategy for treating gastric adenocarcinoma

Hong-Gang Xiang, Xiao Xie, Feng-Qing Hu, Hai-Bo Xiao, Wen-Jie Zhang, Lei Chen
Pages: 1140-1148
Published online on: 02 July 2014

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Article

Knockdown of TNFAIP1 inhibits growth and induces apoptosis in osteosarcoma cells through inhibition of the nuclear factor-κB pathway

Cheng-Lin Zhang, Ce Wang, Wang-Jun  Yan, Rui Gao, Yong-Hua  Li, Xu-Hui Zhou
Pages: 1149-1155
Published online on: 25 June 2014

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Article

β3GnT8 plays an important role in CD147 signal transduction as an upstream modulator of MMP production in tumor cells

Zhi Jiang, Shuijun Hu, Dong Hua, Jianlong Ni, Lan Xu, Yan  Ge, Yinghui Zhou, Zhihong Cheng, Shiliang Wu
Pages: 1156-1162
Published online on: 23 June 2014

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Article

Downregulation of fibroblast growth factor receptor 2 and its isoforms correlates with a high proliferation rate and poor prognosis in high-grade glioma

Ryuji Ohashi, Yoko Matsuda, Toshiyuki Ishiwata, Zenya Naito
Pages: 1163-1169
Published online on: 23 June 2014

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Article

Knockdown of nuclear factor erythroid 2-related factor 2 by lentivirus induces differentiation of glioma stem-like cells

Jianhong Zhu, Handong Wang, Youwu Fan, Yangchun  Hu, Xiangjun Ji, Qing Sun, Huandong Liu
Pages: 1170-1178
Published online on: 10 July 2014

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Article

Wogonoside induces autophagy-related apoptosis in human glioblastoma cells

Li Zhang, Handong Wang, Zixiang Cong, Jianguo Xu, Jianhong Zhu, Xiangjun Ji, Ke Ding
Pages: 1179-1187
Published online on: 26 June 2014

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Article

Cetuximab inhibits cisplatin-induced activation of EGFR signaling in esophageal squamous cell carcinoma

Junhye Kwon, Hyeon-Joon Yoon, Ji-Hee Kim, Tae Sup Lee, In Ho Song, Hae Won Lee, Moon Chul Kang, Jong Ho Park
Pages: 1188-1192
Published online on: 03 July 2014

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Article

MiR-449a functions as a tumor suppressor in endometrial cancer by targeting CDC25A

Wenwei Ye, Jisen Xue, Qian Zhang, Fuyao Li, Wei Zhang, Huijun Chen, Yibo Huang, Feiyun Zheng
Pages: 1193-1199
Published online on: 03 July 2014

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Article

Bioinformatics analysis identifies miR-221 as a core regulator in hepatocellular carcinoma and its silencing suppresses tumor properties

Xing-Xing He, An-Yuan  Guo, Chuan-Rui  Xu, Ying  Chang, Guang-Ya  Xiang, Jing  Gong, Zi-Li  Dan, De-An Tian, Jia-Zhi Liao, Ju-Sheng Lin
Pages: 1200-1210
Published online on: 03 July 2014

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Article

The novel bis-benzylisoquinoline PY35 reverses P-glycoprotein-mediated multidrug resistance

Zhonglian Cao, Meredith Wright, Jiekai Cheng, Xiaoxing  Huang, Li Liu, Lixing Wu, Ping Yang
Pages: 1211-1217
Published online on: 11 July 2014

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Article

Neuregulin-1 induces cancer stem cell characteristics in breast cancer cell lines

Hoiseon Jeong, Jinkyoung Kim, Youngseok Lee, Jae Hong Seo, Sung Ran Hong, Aeree Kim
Pages: 1218-1224
Published online on: 11 July 2014

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Article

Insulin receptor substrate-1 and Golgi phosphoprotein 3 are downstream targets of miR‑126 in esophageal squamous cell carcinoma

Haomiao Li, Fanyu Meng, Jun Ma, Yongkui Yu, Xionghuai Hua, Jianjun Qin, Yin Li
Pages: 1225-1233
Published online on: 11 July 2014

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Article

TNF-related apoptosis-inducing ligand enhances vinorelbine-induced apoptosis and antitumor activity in a preclinical model of non-small cell lung cancer

Kunshou Zhu, Weimin Fang, Yuanmei  Chen, Shaofeng  Lin, Xiaohui Chen
Pages: 1234-1242
Published online on: 11 July 2014

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Article

RRR-α-tocopheryl succinate induces apoptosis in human gastric cancer cells via the NF-κB signaling pathway

Yanpei Sun, Yan Zhao, Liying Hou, Xuguang Zhang, Zhihong Zhang, Kun Wu
Pages: 1243-1248
Published online on: 23 June 2014

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Article

MicroRNA-1 functions as a potential tumor suppressor in osteosarcoma by targeting Med1 and Med31

Chaoyin Jiang, Hua Chen, Lei Shao, Qiaojie Wang
Pages: 1249-1256
Published online on: 20 June 2014

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Article

CCT327 enhances TRAIL-induced apoptosis through the induction of death receptors and downregulation of cell survival proteins in TRAIL-resistant human leukemia cells

Yan-Jin Liu, Ying-Chao Lin, Jang-Chang Lee, Sheng-Chu Kuo, Chi-Tang Ho, Li-Jiau Huang, Daih-Huang Kuo, Tzong-Der Way
Pages: 1257-1264
Published online on: 10 July 2014

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Article

Knockdown of YAP1 inhibits the proliferation of osteosarcoma cells in vitro and in vivo

Zhi Yang, Ming Zhang, Ke Xu, Lin Liu, Wei-Kun Hou, Yuan-Zhen Cai, Peng Xu, Jian-Feng Yao
Pages: 1265-1272
Published online on: 03 July 2014

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Article

E2F1 acts as a negative feedback regulator of c-Myc‑induced hTERT transcription during tumorigenesis

Yafei Zhang, Anran Zhang, Caifei Shen, Bicheng Zhang, Zhiguo Rao, Rongquan Wang, Shiming Yang, Shoubin Ning, Gaoping Mao, Dianchun Fang
Pages: 1273-1280
Published online on: 24 June 2014

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Article

Long non-coding RNA urothelial carcinoma associated 1 induces cell replication by inhibiting BRG1 in 5637 cells

Xiujuan Wang, Yanbing Gong, Bo  Jin, Chenglin  Wu, Jianming  Yang, Le  Wang, Zheng  Zhang, Zebin Mao
Pages: 1281-1290
Published online on: 03 July 2014

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Article

Heat shock protein 20 (HSPB6) regulates apoptosis in human hepatocellular carcinoma cells: Direct association with Bax

Tomoaki Nagasawa, Rie Matsushima-Nishiwaki, Hidenori Toyoda, Junya Matsuura, Takashi Kumada, Osamu Kozawa
Pages: 1291-1295
Published online on: 23 June 2014

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Article

Galium verum aqueous extract strongly inhibits the motility of head and neck cancer cell lines and protects mucosal keratinocytes against toxic DNA damage

Marianne Schmidt, Christine Polednik, Jeanette  Roller, Rudolf Hagen
Pages: 1296-1302
Published online on: 09 July 2014

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Article

Tanshinone IIA inhibits the growth, attenuates the stemness and induces the apoptosis of human glioma stem cells

Liuqi Yang, Huijie Guo, Lihua Dong, Li Wang, Chunlan Liu, Xiujie Wang
Pages: 1303-1311
Published online on: 26 June 2014

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Article

TRAF4 promotes tumorigenesis of breast cancer through activation of Akt

Jie Zhang, Xiaorui Li, Weilong Yang, Xiaokui Jiang, Na Li
Pages: 1312-1318
Published online on: 03 July 2014

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Correction Open Access

[Corrigendum] miR-92a is a critical regulator of the apoptosis pathway in glioblastoma with inverse expression of BCL2L11

Huanjiang Niu, Kun Wang, Anling Zhang, Shuxu Yang, Zhengfei Song, Wei Wang, Cong Qian, Xinwei Li, Yinxin Zhu, Yirong Wang
Pages: 1319-1319
Published online on: 10 July 2014

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January-2026 Volume 55 Issue 1

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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