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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2015 Volume 33 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Regulation of the C/EBPα signaling pathway in acute myeloid leukemia (Review)

Guanhua Song, Lin Wang, Kehong Bi, Guosheng Jiang
Pages: 2099-2106
Published online on: 10 March 2015

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Review

Gene therapy strategies using engineered stem cells for treating gynecologic and breast cancer patients (Review)

Ye-Seul Kim, Kyung-A Hwang, Ryeo-Eun Go, Cho-Won Kim, Kyung-Chul Choi
Pages: 2107-2112
Published online on: 10 March 2015

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Review

New insights into the mechanism of F-box proteins in colorectal cancer (Review)

Jian Gong, Jirong Huo
Pages: 2113-2120
Published online on: 27 February 2015

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Review

Association of annexin A2 with cancer development (Review)

Xiao-Heng Xu, Wei Pan, Li-Hua Kang, Hui Feng, Yan-Qiu Song
Pages: 2121-2128
Published online on: 05 March 2015

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Article Open Access

Lactotrophs: The new and major source for VEGF secretion and the influence of ECM on rat pituitary function in vitro

Joachim Alfer, Joseph Neulen, Andreas Gaumann
Pages: 2129-2134
Published online on: 13 March 2015

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Article Open Access

Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts

Hiroshi Tsukihara, Fumio Nakagawa, Kazuki Sakamoto, Keiji Ishida, Nozomu Tanaka, Hiroyuki Okabe, Junji Uchida, Kenichi Matsuo, Teiji Takechi
Pages: 2135-2142
Published online on: 23 March 2015

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Article Open Access

Synergy of BID with doxorubicin in the killing of cancer cells

Emilia Joanna Orzechowska, Agnieszka Girstun, Krzysztof Staron, Joanna Trzcinska-Danielewicz
Pages: 2143-2150
Published online on: 09 March 2015

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Article Open Access

Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan

Takeyuki Sawano, Takeshi Shimizu, Toshiyuki Yamada, Naoki Nanashima, Takuya Miura, Satoko Morohashi, Daisuke Kudo, Feng Mao Hui, Hiroshi Kijima, Kenichi Hakamada, Shigeki Tsuchida
Pages: 2151-2160
Published online on: 20 February 2015

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Article Open Access

Increased expression of interleukin-6 predicts poor response to chemoradiotherapy and unfavorable prognosis in oral squamous cell carcinoma

Teppei Jinno, Shintaro Kawano, Yasuyuki Maruse, Ryota Matsubara, Yuichi Goto, Taiki Sakamoto, Yuma Hashiguchi, Naoki Kaneko, Hideaki Tanaka, Ryoji Kitamura, Takeshi Toyoshima, Akiko Jinno, Masafumi Moriyama, Kazunari Oobu, Tamotsu Kiyoshima, Seiji Nakamura
Pages: 2161-2168
Published online on: 06 March 2015

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Article Open Access

DHFR-mediated effects of methotrexate in medulloblastoma and osteosarcoma cells: The same outcome of treatment with different doses in sensitive cell lines

Jakub Neradil, Gabriela Pavlasova, Martin Sramek, Michal Kyr, Renata Veselska, Jaroslav Sterba
Pages: 2169-2175
Published online on: 26 February 2015

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Article Open Access

Upregulation of microRNA-126-5p is associated with drug resistance to cytarabine and poor prognosis in AML patients

Yoshihiko Shibayama, Takeshi Kondo, Hiroki Ohya, Shin-Ichi Fujisawa, Takanori Teshima, Ken Iseki
Pages: 2176-2182
Published online on: 06 March 2015

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Article

Effect of REG Iα protein on angiogenesis in gastric cancer tissues

Ken Hara, Hirokazu Fukui, Chao Sun, Yoshitaka Kitayama, Hirotsugu Eda, Takahisa Yamasaki, Takashi Kondo, Toshihiko Tomita, Tadayuki Oshima, Jiro Watari, Takahiro Fujimori, Hiroto Miwa
Pages: 2183-2189
Published online on: 23 March 2015

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Article

Paris saponin II inhibits human ovarian cancer cell‑induced angiogenesis by modulating NF-κB signaling

Mei Yang, Juan Zou, Hongmei Zhu, Shanling Liu, He Wang, Peng Bai, Xue Xiao
Pages: 2190-2198
Published online on: 05 March 2015

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Article

Epigenetic bivalent marking is permissive to the synergy of HDAC and PARP inhibitors on TXNIP expression in breast cancer cells

Federica Baldan, Catia Mio, Elisa Lavarone, Carla Di Loreto, Fabio Puglisi, Giuseppe Damante, Cinzia Puppin
Pages: 2199-2206
Published online on: 23 March 2015

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Article

Differential proteomic profiling of primary and recurrent chordomas

Su Chen, Wei Xu, Jian Jiao, Dongjie Jiang, Jian Liu, Tenghui Chen, Zongmiao Wan, Leqin Xu, Zhenhua Zhou, Jianru Xiao
Pages: 2207-2218
Published online on: 26 February 2015

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Article

Two-dimensional gel electrophoresis analysis of the leiomyoma interstitial fluid reveals altered protein expression with a possible involvement in pathogenesis

Blendi Ura, Federica Scrimin, Fabrizio Zanconati, Giorgio Arrigoni, Lorenzo Monasta, Andrea Romano, Rubina Banco, Marina Zweyer, Daniela Milani, Giuseppe Ricci
Pages: 2219-2226
Published online on: 03 March 2015

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Article

High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo

Jiao Xu, Min Yong, Jia Li, Xiaojing Dong, Tinghe Yu, Xiao Fu, Lina Hu
Pages: 2227-2234
Published online on: 03 March 2015

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Article

Simvastatin exhibits antiproliferative effects on spheres derived from canine mammary carcinoma cells

Cristian G. Torres, Araceli Olivares, Caroll Stoore
Pages: 2235-2244
Published online on: 13 March 2015

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Article

Humoral autoimmune response to nucleophosmin in the immunodiagnosis of hepatocellular carcinoma

Mei Liu, Armando Varela-Ramirez, Jitian Li, Liping Dai, Renato J. Aguilera, Jian-Ying Zhang
Pages: 2245-2252
Published online on: 16 March 2015

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Article

LMP-1 induces survivin expression to inhibit cell apoptosis through the NF-κB and PI3K/Akt signaling pathways in nasal NK/T-cell lymphoma

Lu Sun, Yu Zhao, Huaiyin Shi, Chao Ma, Lixin Wei
Pages: 2253-2260
Published online on: 10 March 2015

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Article

Muscle-specific E3 ubiquitin ligases are involved in muscle atrophy of cancer cachexia: An in vitro and in vivo study

Lei Yuan, Jun Han, Qingyang Meng, Qiulei Xi, Qiulin Zhuang, Yi Jiang, Yusong Han, Bo Zhang, Jing Fang, Guohao Wu
Pages: 2261-2268
Published online on: 09 March 2015

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Article

Anti-metastatic effects of DNA vaccine encoding single‑chain trimer composed of MHC I and vascular endothelial growth factor receptor 2 peptide

Ruiling Chen, Shengchao Wang, Yunliang Yao, Yun Zhou, Chong Zhang, Jie Fang, Dayong Zhang, Lihuang Zhang, Jianping Pan
Pages: 2269-2276
Published online on: 26 February 2015

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Article

Mcl-1 downregulation sensitizes glioma to bortezomib-induced apoptosis

Yang Zhang, Xiaobo Zhu, Kun Hou, Jinchuan Zhao, Zhiguo Han, Xiaona Zhang
Pages: 2277-2284
Published online on: 23 March 2015

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Article

Knockdown of flotillin-2 impairs the proliferation of breast cancer cells through modulation of Akt/FOXO signaling

Gui'e Xie, Jinlong Li, Jingsong Chen, Xuewei Tang, Shaoqing Wu, Can Liao
Pages: 2285-2290
Published online on: 03 March 2015

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Article

The ALDH1+ subpopulation of the human NMFH‑1 cell line exhibits cancer stem-like characteristics

Dejian Li, Tao Zhang, Wenguang Gu, Peng Li, Xiangyang Cheng, Tiejun Tong, Wenbo Wang
Pages: 2291-2298
Published online on: 09 March 2015

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Article

HDAC inhibitors induce epithelial-mesenchymal transition in colon carcinoma cells

Meiying Ji, Eun Jeoung Lee, Ki Bae Kim, Yangmi Kim, Rohyun Sung, Sang-Jeon Lee, Don Soo Kim, Seon Mee Park
Pages: 2299-2308
Published online on: 23 March 2015

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Article

MicroRNA-326 functions as a tumor suppressor in colorectal cancer by targeting the nin one binding protein

Lei Wu, Hui Hui, Li-Juan Wang, Hao Wang, Qiu-Fang Liu, Su-Xia Han
Pages: 2309-2318
Published online on: 06 March 2015

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Article

Repression of engrailed 2 inhibits the proliferation and invasion of human bladder cancer in vitro and in vivo

Yunfei Li, Haitao Liu, Caiyong Lai, Zexuan Su, Baoli Heng, Shuangquan Gao
Pages: 2319-2330
Published online on: 17 March 2015

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Article

Inhibition of the autophagy flux by gingerol enhances TRAIL-induced tumor cell death

Uddin Md. Nazim, Jae-Kyo Jeong, Jae-Won Seol, Jin Hur, Seong-Kug Eo, John-Hwa Lee, Sang-Youel Park
Pages: 2331-2336
Published online on: 20 March 2015

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Article

Oncogene ATAD2 promotes cell proliferation, invasion and migration in cervical cancer

Le Zheng, Tianren Li, Yi Zhang, Yi Guo, Jihang Yao, Lei Dou, Kejun Guo
Pages: 2337-2344
Published online on: 20 March 2015

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Article

Prognostic value of vascular endothelial growth factor and hypoxia-inducible factor 1α in canine malignant mammary tumors

Marina Gobbe Moschetta, Larissa Bazela Maschio, Bruna Victorasso Jardim-Perassi, Gabriela Bottaro Gelaleti, Juliana Ramos Lopes, Camila Leonel, Naiane Do Nascimento Gonçalves, Lívia Carvalho Ferreira, Gustavo Rodrigues Martins, Thaiz Ferraz Borin, Debora Aparecida Pires De Campos Zuccari
Pages: 2345-2353
Published online on: 16 March 2015

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Article

MicroRNA-424 may function as a tumor suppressor in endometrial carcinoma cells by targeting E2F7

Quan Li, Xiang-Mei Qiu, Qing-Han Li, Xiao-Yan Wang, Li Li, Min Xu, Min Dong, Yan-Bing Xiao
Pages: 2354-2360
Published online on: 20 February 2015

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Article

Preclinical assessment of early tumor response after irradiation by positron emission tomography with 2-amino-[3-11C]isobutyric acid

Atsushi B. Tsuji, Aya Sugyo, Hitomi Sudo, Chie Suzuki, Hidekatsu Wakizaka, Ming-Rong Zhang, Koichi Kato, Tsuneo Saga
Pages: 2361-2367
Published online on: 20 March 2015

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Article

Tetramethylpyrazine inhibits the proliferation of acute lymphocytic leukemia cell lines via decrease in GSK-3β

Xiao-Jing Wang, You-Hua Xu, Gui-Cun Yang, Hong-Xia Chen, Ping Zhang
Pages: 2368-2374
Published online on: 18 March 2015

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Article

Expression of NEDD9 in hepatocellular carcinoma and its clinical significance

Peng Lu, Zhi-Peng Wang, Zheng Dang, Zhi-Gang Zheng, Xiao Li, Liang Zhou, Rui Ding, Shu-Qiang Yue, Ke-Feng Dou
Pages: 2375-2383
Published online on: 18 March 2015

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Article

Ribavirin as a tri-targeted antitumor repositioned drug

Erick De la Cruz-Hernandez, Jose Luis Medina-Franco, Jaenai Trujillo, Alma Chavez-Blanco, Guadalupe Dominguez-Gomez, Enrique Perez-Cardenas, Aurora Gonzalez-Fierro, Lucia Taja-Chayeb, Alfonso Dueñas-Gonzalez
Pages: 2384-2392
Published online on: 25 February 2015

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Article

MicroRNA‑494 promotes cervical cancer proliferation through the regulation of PTEN

Yong‑Kang Yang, Wen‑Yan Xi, Ru‑Xing Xi, Jing‑Yuan Li, Qin Li, Yan‑E Gao
Pages: 2393-2401
Published online on: 26 February 2015

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Article

Targeting FoxM1 inhibits proliferation, invasion and migration of nasopharyngeal carcinoma through the epithelial‑to-mesenchymal transition pathway

Chao Yu, Lili Chen, Lin Yie, Lei Wei, Taoyu Wen, Yanan Liu, Hongyan Chen
Pages: 2402-2410
Published online on: 04 March 2015

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Article

Pemetrexed induces apoptosis in malignant mesothelioma and lung cancer cells through activation of reactive oxygen species and inhibition of sirtuin 1

Ki-Eun Hwang, Young-Suk Kim, Yu-Ri Hwang, Su-Jin Kwon, Do-Sim Park, Byong‑Ki Cha, Byoung-Ryun Kim, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim
Pages: 2411-2419
Published online on: 04 March 2015

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Article

Establishment of an expression platform of OATP1B1 388GG and 521CC genetic polymorphism and the therapeutic effect of tamoxifen in MCF-7 cells

Zhichen Pu, Xuefeng Zhang, Qun Chen, Xiaolong Yuan, Haitang Xie
Pages: 2420-2428
Published online on: 18 March 2015

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Article

Demethoxycurcumin induces the apoptosis of human lung cancer NCI-H460 cells through the mitochondrial-dependent pathway

Yang-Ching Ko, Jin-Cherng Lien, Hsin-Chung Liu, Shu-Chun Hsu, Bin-Chuan Ji, Mei-Due Yang, Wu-Huei Hsu, Jing-Gung Chung
Pages: 2429-2437
Published online on: 18 March 2015

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Article

RNA-binding motif protein 5 negatively regulates the activity of Wnt/β-catenin signaling in cigarette smoke-induced alveolar epithelial injury

Yu-Qiu Hao, Zhen-Zhong Su, Xue-Jiao Lv, Ping Li, Peng Gao, Chen Wang, Yue Bai, Jie Zhang
Pages: 2438-2444
Published online on: 03 March 2015

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Article

Investigation of the roles of exosomes in colorectal cancer liver metastasis

Xia Wang, Xiaoling Ding, Lijuan Nan, Yiting Wang, Jing Wang, Zhiqiang Yan, Wei Zhang, Jihong Sun, Wei Zhu, Bing Ni, Suzhen Dong, Lei Yu
Pages: 2445-2453
Published online on: 09 March 2015

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Article

PLU-1/JARID1B overexpression predicts proliferation properties in head and neck squamous cell carcinoma

Zhibin Cui, Liwei Song, Zhaoyuan Hou, Yifan Han, Yuhua Hu, Yadi Wu, Wantao Chen, Li Mao
Pages: 2454-2460
Published online on: 12 March 2015

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Article

HBx co-localizes with COXIII in HL-7702 cells to upregulate mitochondrial function and ROS generation

Lai-Yu Zou, Bi-Yun Zheng, Xue-Fen Fang, Dan Li, Yue-Hong Huang, Zhi-Xin Chen, Lin-Ying Zhou, Xiao-Zhong Wang
Pages: 2461-2467
Published online on: 13 March 2015

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Article

Combination of IL-24 and cisplatin inhibits angiogenesis and lymphangiogenesis of cervical cancer xenografts in a nude mouse model by inhibiting VEGF, VEGF-C and PDGF-B

Zhaoxia Wang, Jiyuan Lv, Tiantian Zhang
Pages: 2468-2476
Published online on: 16 March 2015

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Article

Lentiviral vector-mediated doxycycline-inducible USP39 shRNA or cDNA expression in triple-negative breast cancer cells

Shihai Liu, Xiangping Liu, Haibo Wang, Quan Zhou, Ye Liang, Aihua Sui, Ruyong Yao, Bin Zhao, Ming Sun
Pages: 2477-2483
Published online on: 20 March 2015

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Article

Identification of potential targets for diallyl disulfide in human gastric cancer MGC-803 cells using proteomics approaches

Bo Su, Jian Su, Hui He, Youhua Wu, Hong Xia, Xi Zeng, Wenxiang Dai, Xiaohong Ai, Hui Ling, Hao Jiang, Qi Su
Pages: 2484-2494
Published online on: 17 March 2015

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Article

Modulation of tumor cell migration, invasion and cell-matrix adhesion by human monopolar spindle-one-binder 2

Wenjuan Wu, Xizhi Zhang, Haonan Qin, Wanxin Peng, Qingyu Xue, Houning Lv, Hua Zhang, Yumei Qiu, Haichao Cheng, Yu Zhang, Zhiyong Yu, Weigan Shen
Pages: 2495-2503
Published online on: 16 March 2015

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Article

miR-141 confers docetaxel chemoresistance of breast cancer cells via regulation of EIF4E expression

Ya-Sai Yao, Wen-Sheng Qiu, Ru-Yong Yao, Qian Zhang, Li‑Kun Zhuang, Fei Zhou, Li-Bin Sun, Lu Yue
Pages: 2504-2512
Published online on: 18 March 2015

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Article

Antiproliferative effects of β-blockers on human colorectal cancer cells

M. Coelho, M. Moz, G. Correia, A. Teixeira, R. Medeiros, L. Ribeiro
Pages: 2513-2520
Published online on: 23 March 2015

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Article

Mothers' acceptance of human papillomavirus (HPV) vaccination for daughters in a country with a high prevalence of HPV

Susanna Alder, Sofia Gustafsson, Claudia Perinetti, Miriam Mints, Karin Sundström, Sonia Andersson
Pages: 2521-2528
Published online on: 25 February 2015

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Article

Inhibition of microRNA-17/20a suppresses cell proliferation in gastric cancer by modulating UBE2C expression

Yingyi Zhang, Ting Han, Guo Wei, Yajie Wang
Pages: 2529-2536
Published online on: 05 March 2015

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Article

Synergistic growth inhibition by sorafenib and cisplatin in human osteosarcoma cells Retraction in /10.3892/or.2021.8144

Qu Yang, Shanyong Zhang, Mingyang Kang, Rongpeng Dong, Jianwu Zhao
Pages: 2537-2544
Published online on: 04 March 2015

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Article

Cytotoxic T lymphocyte-associated antigen 4 inhibition increases the antitumor activity of adoptive T-cell therapy when carried out with naïve rather than differentiated T cells

Takeshi Ishikawa, Satoko Adachi, Tetsuya Okayama, Satoshi Kokura, Katsura Mizushima, Toshifumi Doi, Tatsuzo Matsuyama, Naoyuki Sakamoto, Kazuhiro Katada, Kazuhiro Kamada, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Yuji Naito, Yoshito Itoh, Toshikazu Yoshikawa
Pages: 2545-2552
Published online on: 24 February 2015

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Article

Salidroside inhibits the growth of human breast cancer in vitro and in vivo

Gang Zhao, Aiping Shi, Zhimin Fan, Ye Du
Pages: 2553-2560
Published online on: 17 March 2015

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Article

Matrine induces mitochondrial apoptosis in cisplatin‑resistant non-small cell lung cancer cells via suppression of β-catenin/survivin signaling

Huan-Qin Wang, Jian-Jun Jin, Jing Wang
Pages: 2561-2566
Published online on: 09 March 2015

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Article

Genome‑wide analysis of histone modifications by ChIP‑chip to identify silenced genes in gastric cancer

Xinjiang Zhu, Jian Liu, Xiaoyang Xu, Chundong Zhang, Dongqiu Dai
Pages: 2567-2574
Published online on: 27 February 2015

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Effects of the knockdown of death-associated protein 3 expression on cell adhesion, growth and migration in breast cancer cells

Umar Wazir, Andrew J. Sanders, Ahmad M.A. Wazir, Lin Ye, Wen G. Jiang, Irina C. Ster, Anup K. Sharma, Kefah Mokbel
Pages: 2575-2582
Published online on: 02 March 2015

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Podocalyxin promotes glioblastoma multiforme cell invasion and proliferation by inhibiting angiotensin-(1-7)/Mas signaling

Bo Liu, Yu Liu, Yugang Jiang
Pages: 2583-2591
Published online on: 20 February 2015

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Article

miR-182 promotes cell growth and invasion by targeting forkhead box F2 transcription factor in colorectal cancer

Yu Zhang, Xinying Wang, Zhongqiu Wang, Hui Tang, Hong Fan, Qiang Guo
Pages: 2592-2598
Published online on: 04 March 2015

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Article

MCM2 is a therapeutic target of lovastatin in human non-small cell lung carcinomas

Xu Zhang, Yang Teng, Fang Yang, Meng Wang, Xuan Hong, Lei-Guang Ye, Yi-Na Gao, Gong-Yan Chen
Pages: 2599-2605
Published online on: 27 February 2015

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miR-218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Pages: 2606-2612
Published online on: 18 March 2015

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Article

BAG3 increases the invasiveness of uterine corpus carcinoma cells by suppressing miR‑29b and enhancing MMP2 expression

Shutaro Habata, Masahiro Iwasaki, Asuka Sugio, Miwa Suzuki, Masato Tamate, Seiro Satohisa, Ryoichi Tanaka, Tsuyoshi Saito
Pages: 2613-2621
Published online on: 04 March 2015

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Article

OCT4B modulates OCT4A expression as ceRNA in tumor cells

Dong Li, Zheng-Kai Yang, Jing-Yi Bu, Chun-Yan Xu, Hui Sun, Jie-Bing Tang, Ping Lin, Wen Cheng, Ning Huang, Rong-Jun Cui, Xiao-Guang Yu, Xiu-Lan Zheng
Pages: 2622-2630
Published online on: 18 March 2015

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Article

Slug mediates nasopharyngeal carcinoma radioresistance via downregulation of PUMA in a p53-dependent and -independent manner

Ting Xu, Bin Fan, Chunjiang Lv, Dajiang Xiao
Pages: 2631-2638
Published online on: 23 March 2015

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Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G2/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells

Jong-Yun Kim, Hye-Eun Choi, Hwi-Ho Lee, Ji-Sun Shin, Dong‑Hyun Shin, Jung-Hye Choi, Yong Sup Lee, Kyung-Tae Lee
Pages: 2639-2647
Published online on: 20 March 2015

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Article

Aberrant hypomethylation-mediated CD147 overexpression promotes aggressive tumor progression in human prostate cancer

Yu-Xiang Liang, Ru-Jun Mo, Hui-Chan He, Jia-Hong Chen, Jun Zou, Zhao-Dong Han, Jian-Ming Lu, Chao Cai, Yan-Ru Zeng, Wei-De Zhong, Chin-Lee Wu
Pages: 2648-2654
Published online on: 20 March 2015

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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