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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2013 Volume 32 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

The role of ghrelin in patients with functional dyspepsia and its potential clinical relevance (Review)

Takakazu Yagi, Akihiro Asakawa, Hirotaka Ueda, Shouichi Miyawaki, Akio Inui
Pages: 523-531
Published online on: 14 June 2013

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Article

Epigenetic aberrations in myeloid malignancies (Review)

Shinichiro Takahashi
Pages: 532-538
Published online on: 12 June 2013

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Review Open Access

Viral involvement in the pathogenesis and clinical features of ophthalmic pterygium (Review)

Aikaterini K. Chalkia, Demetrios A. Spandidos, Efstathios T. Detorakis
Pages: 539-543
Published online on: 12 July 2013

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Article Open Access

Comparative proteomic profiling of soleus, extensor digitorum longus, flexor digitorum brevis and interosseus muscles from the mdx mouse model of Duchenne muscular dystrophy

Steven Carberry, Heinrich Brinkmeier, Yaxin Zhang, Claudia K. Winkler, Kay Ohlendieck
Pages: 544-556
Published online on: 03 July 2013

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Article Open Access

Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma

Junying Chen, Desheng Yao, Yue Li, Hong Chen, Chanjuan He, Nan Ding, Yan Lu, Tingyu Ou, Shan Zhao, Li Li, Fengyi Long
Pages: 557-567
Published online on: 21 June 2013

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Article Open Access

Effect of angiopoietin-like protein 4 on rat pulmonary microvascular endothelial cells exposed to LPS

Yuxi Wang, Hailong Chen, Hailong Li, Jingwen Zhang, Yanyan Gao
Pages: 568-576
Published online on: 20 June 2013

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Article

Extracts of Koelreuteria henryi Dummer induce apoptosis and autophagy by inhibiting dihydrodiol dehydrogenase, thus enhancing anticancer effects

Yung-Yen Chiang, Shu-Li Wang, Cheng-Lin Yang, Hui-Yu Yang, Hsiu-Ching Yang, J. N. Sudhakar, Ching-Kuo Lee, Hsiu-Wen Huang, Chien-Min Chen, Shiow-Her Chiou, Shu-Fen Chiang, Hsin-Yuan Fang, Chih-Yi Chen, Shwn-Huey Shieh, Kuan-Chih Chow
Pages: 577-584
Published online on: 12 July 2013

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Article

Loss of caveolin-1 promotes endothelial-mesenchymal transition during sepsis: A membrane proteomic study

Xiaobo Huang, Lingai Pan, Hong Pu, Yiping Wang, Xiaoqin Zhang, Chunling Li, Zhenglin Yang
Pages: 585-592
Published online on: 05 July 2013

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Article

miR-503 regulates the resistance of non-small cell lung cancer cells to cisplatin by targeting Bcl-2

Tianzhu Qiu, Li Zhou, Tongshan Wang, Jing Xu, Jian Wang, Wenjiao Chen, Xin Zhou, Zebo Huang, Wei Zhu, Yongqian Shu, Ping Liu
Pages: 593-598
Published online on: 12 July 2013

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Article

Changes in expression and distribution of attractin in the testes of rats at different developmental stages

Xuejun Shang, Juan Liu, Qiuyu Xu, Qi Zhang, Bo Ma, Yonglu Wang, Zyuehua Zhang, Xiaomei Cao, Xuxin Zhan
Pages: 599-606
Published online on: 21 June 2013

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Article

Proteomic analysis of endothelial progenitor cells exposed to oxidative stress

Ying Liu, Jun Wei, Ming Chang, Zhiqiang Liu, Dawei Li, Shengying Hu, Linsen Hu
Pages: 607-614
Published online on: 18 June 2013

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Article

Smac/DIABLO regulates the apoptosis of hypertrophic scar fibroblasts

Bao-Heng Liu, Liang Chen, Shi-Rong Li, Zhen-Xiang Wang, Wen-Guang Cheng
Pages: 615-622
Published online on: 15 July 2013

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Article

Inhibitory effects of STAT3 decoy oligodeoxynucleotides on human epithelial ovarian cancer cell growth in vivo

Xiaolei Zhang, Peishu Liu, Bo Zhang, Hongluan Mao, Liang Shen, Yanhui Ma
Pages: 623-628
Published online on: 04 July 2013

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Article

Curcumin inhibits the proliferation of airway smooth muscle cells in vitro and in vivo

Xin Zeng, Ying Cheng, Yuejun Qu, Jide Xu, Zhiyuan Han, Tingting Zhang
Pages: 629-636
Published online on: 27 June 2013

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Article

Salidroside reduces cold-induced mucin production by inhibiting TRPM8 activation

Qi Li, Xiang-Dong Zhou, Victor P. Kolosov, Juliy M. Perelman
Pages: 637-646
Published online on: 05 July 2013

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Article

Polymorphisms and expression of the WNT8A gene in Hirschsprung's disease

Hong Gao, Dong Chen, Xiaomei Liu, Mei Wu, Jie Mi, Weilin Wang
Pages: 647-652
Published online on: 05 July 2013

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Article

Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand-mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Pages: 653-660
Published online on: 11 July 2013

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Article

A heterozygous missense SCN5A mutation associated with early repolarization syndrome

Ning Li, Rongrong Wang, Cuihong Hou, Yinhui Zhang, Siyong Teng, Jielin Pu
Pages: 661-667
Published online on: 21 June 2013

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Article

Analysis of boutique arrays: A universal method for the selection of the optimal data normalization procedure

Barbara Uszczyńska, Joanna Zyprych-Walczak, Luiza Handschuh, Alicja Szabelska, Maciej Kaźmierczak, Wiesława Woronowicz, Piotr Kozłowski, Michał M. Sikorski, Mieczysław Komarnicki, Idzi Siatkowski, Marek Figlerowicz
Pages: 668-684
Published online on: 15 July 2013

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Article

EETs and CYP2J2 inhibit TNF-α-induced apoptosis in pulmonary artery endothelial cells and TGF-β1-induced migration in pulmonary artery smooth muscle cells

Wenjing Feng, Xizhen Xu, Gang Zhao, Geng Li, Tiantian Liu, Junjie Zhao, Ruolan Dong, Dao Wen Wang, Ling Tu
Pages: 685-693
Published online on: 05 July 2013

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Article

Association between mRNA levels of DNMT1, DNMT3A, DNMT3B, MBD2 and LINE-1 methylation status in infants with tetralogy of Fallot

Wei Sheng, Yanyan Qian, Huijun Wang, Xiaojing Ma, Ping Zhang, Long Chen, Duan Ma, Guoying Huang
Pages: 694-702
Published online on: 02 July 2013

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Article

Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells

Yusuke Tajitsu, Ryuji Ikeda, Yukihiko Nishizawa, Hirofumi Mataki, Xiao-Fang Che, Tomoyuki Sumizawa, Mina Nitta, Tatsuya Yamaguchi, Masatatsu Yamamoto, Sho Tabata, Shin-Ichi Akiyama, Katsushi Yamada, Tatsuhiko Furukawa, Yasuo Takeda
Pages: 703-708
Published online on: 02 July 2013

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Article

Induction of Hantaan virus-specific immune responses in C57BL/6 mice by immunization with a modified recombinant adenovirus containing the chimeric gene, GcS0.7

Kai Li, Pu-Yuan Li, Xing-An Wu, Liang Zhang, Zi-Yu Liu, Lan Yu, Lei Zhang, Lin-Feng Cheng, Wen-Tao Bai, Fang-Lin Zhang, Zhi-Kai Xu
Pages: 709-716
Published online on: 20 June 2013

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Article

Tetramethylpyrazine inhibits angiotensin II-induced cardiomyocyte hypertrophy and tumor necrosis factor-α secretion through an NF-κB-dependent mechanism

Liangzhu Yu, Tonghui She, Mincai Li, Chunrong Shi, Lu Han, Menglin Cheng
Pages: 717-722
Published online on: 09 July 2013

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Article

Effects of estrogen receptor α and β on the expression of visfatin and retinol-binding protein 4 in 3T3-L1 adipocytes

Un Suk Jung, Kang Jin Jeong, Jae Ku Kang, Kyongwook Yi, Jung-Ho Shin, Hong Seog Seo, Tak Kim, Sun-Haeng Kim, Jun-Young Hur
Pages: 723-728
Published online on: 12 July 2013

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Article

Activation of RAW264.7 mouse macrophage cells in vitro through treatment with recombinant ricin toxin-binding subunit B: Involvement of protein tyrosine, NF-κB and JAK-STAT kinase signaling pathways

Na Xu, Hongyan Yuan, Wensen Liu, Songyan Li, Yang Liu, Jiayu Wan, Xiaoyan Li, Rui Zhang, Yaping Chang
Pages: 729-735
Published online on: 02 July 2013

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Article

Vigna angularis inhibits mast cell-mediated allergic inflammation

Hui-Hun Kim, Sung-Wan Kim, Duk-Sil Kim, Hyun-Mee Oh, Mun-Chual Rho, Sang-Hyun Kim
Pages: 736-742
Published online on: 04 July 2013

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Article Open Access

Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Review Open Access

Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Review Open Access

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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Review Open Access

High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Published online on: 01 December 2025

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Published online on: 01 December 2025

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