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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2025 Volume 32 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Activation of pyroptosis impairs basal cell differentiation in the nasal epithelium in chronic rhinosinusitis with nasal polyps

Guangmin Zhang, Shengxi Jin, Jiane Liu, Yiping Du, Zhiyuan Li, Linlin Liu, Xiaohui Xu, Zheng Wang, Shu Yan
Article Number: 229
Published online on: 12 June 2025

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Metabolic abnormalities of the cortico‑striato‑thalamo‑cortical circuit of rats with tic disorder

Jingru Yu, Jiateng Su, Guo Yu, Zhongyang Zhang, Yue Wu, Gong Xiao, Xin Zhang, Juanjuan Hao
Article Number: 228
Published online on: 10 June 2025

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Review

Advances in MCFA to ameliorate lipoatrophic hepatocyte injury and lipid metabolism disorders (Review)

Haibo Xu, Baogui Wang, Qi Wang, Chunlong Sun, Wen Du
Article Number: 227
Published online on: 10 June 2025

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Retraction Open Access

[Retracted] Protection of Luteolin‑7‑O‑glucoside against apoptosis induced by hypoxia/reoxygenation through the MAPK pathways in H9c2 cells

Shenjie Chen, Bingsheng Yang, Yifei Xu, Yiqing Rong, Yuangang Qiu
Article Number: 226
Published online on: 10 June 2025

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Article Open Access

Matrix metalloproteinase‑9 in hemorrhagic transformation after acute ischemic stroke (Review)

Pingping Guo, Hongmin Li, Xiangyu Zhang, Yang Liu, Sara Xue, Voon Wee Yong, Mengzhou Xue
Article Number: 225
Published online on: 05 June 2025

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Article Open Access

A novel variant in the MAP3K1 genomic locus reveals abnormal cell apoptosis as a potential pathogenic mechanism in 46, XY disorders of sex development

Yufu Lu, Sijia Wei, Shuang Wang, Jingzhi Zhang, Yongjie Xu, Changyudong Huang, Wei Pan, Zhengrong Wang
Article Number: 224
Published online on: 05 June 2025

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Article Open Access

Otubain 2 stabilizes TNF‑receptor associated factor 3 to accelerate bone fracture healing

Li Zhang, Jialiang Guo, Shan Feng, Yue Zheng, Haixu Wang, Huijie Ma, Wei Chen, Yingze Zhang, Zhiyong Hou
Article Number: 223
Published online on: 05 June 2025

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Review Open Access

IPSC‑derived NK cells for immunotherapy and therapeutic perspective (Review)

Xiyao Wei, Chen Su, Yueyang Liu, Ningbo Wei, Kexin Xiang, Qijun Qian, Zenghui Xu
Article Number: 222
Published online on: 03 June 2025

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β‑elemene attenuates IRI‑AKI by inhibiting inflammation and apoptosis via suppression of the TLR4/MyD88/NF‑κB/MAPK signal axis activation

Qiming Gong, Yakun Wang, Fahui Liu, Yuqing Huang, Luxin Li, Dongsheng Cheng, Shoujun Bai, Wenjuan Sun
Article Number: 221
Published online on: 03 June 2025

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Advances in research on the pathogenesis and signaling pathways associated with postoperative delirium (Review)

Weiqing Li, Qin Shi, Ronghua Bai, Jingzheng Zeng, Lu Lin, Xuemei Dai, Qingqing Huang, Gu Gong
Article Number: 220
Published online on: 03 June 2025

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Retraction Open Access

[Retracted] Antiproliferation effect of the uremic toxin para‑cresol on endothelial progenitor cells is related to its antioxidant activity

Limin Pan, Xiaoting Ye, Jiguang Ding, Yu Zhou
Article Number: 219
Published online on: 02 June 2025

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Development of an innovative approach for early diagnosis of cervical cancer using TCR‑like antibodies targeting HPV18 E6 and E7 peptides

Bassam Ali Sachit, Sylvia Annabel Dass, Rehasri Selva Rajan, Gee Jun Tye, Venugopal Balakrishnan
Article Number: 218
Published online on: 02 June 2025

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Splice‑site variant c.3531+1G>T in COL1A1 in a family with osteogenesis imperfecta

Yanru Huang, Yixi Zhou, Lutan Zhang, Ye Shen, Xingmei Yao, Jieqiong Xie, Libin Mei, Yunsheng Ge
Article Number: 217
Published online on: 28 May 2025

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Correction Open Access

[Corrigendum] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 216
Published online on: 28 May 2025

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Reduced iron bioavailability drives acute high‑altitude lung injury through HIF1α activation and mitophagy

Yumei Geng, Yu Hu, Huijie Wang, Fang Zhang, Ri-Li Ge
Article Number: 215
Published online on: 27 May 2025

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Retraction Open Access

[Retracted] Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3‑kinase/protein kinase B signaling pathway in mice during cardiac surgery

Zhibing Pi, Hai Lin, Jianping Yang
Article Number: 214
Published online on: 27 May 2025

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Review Open Access

Chimeric antigen receptor T cell immunotherapy‑associated hemophagocytic lymphohistiocytosis: Pathogenesis, clinical manifestation, diagnosis and management compared with cytokine release syndrome (Review)

Jinglin Hu, Cuicui Feng, Lingbo He, Yini Wang
Article Number: 213
Published online on: 26 May 2025

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Review Open Access

Role of amino acid metabolism in osteoporosis: Effects on the bone microenvironment and treatment strategies (Review)

Chang Zhou, Jiaheng Zhang, Qizhi Liu, Yanghongxu Guo, Mengyuan Li, Jing Tao, Sujuan Peng, Ronghui Li, Xianguang Deng, Guomin Zhang, Huiping Liu
Article Number: 212
Published online on: 26 May 2025

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Mechanistic exploration of hexokinase 2 and metabolism in diabetic cardiomyopathy

Bo Li, Xu Zhao, Liming Ma, Xiaoying Wang, Yan Ding, Yi Zhang
Article Number: 211
Published online on: 26 May 2025

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Exosomal miRNAs in pancreatitis: Mechanisms and potential applications (Review)

Liwei Wang, Jiaying Zhang, Ziwei He, Xiangding Kong, Chengxiang Liu, Yingzhi Xia, Ming Yang, Kuanyu Wang
Article Number: 210
Published online on: 23 May 2025

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Insulin‑like growth factor in cancer: New perspectives (Review)

Duoming Wu, Shi Dong, Wence Zhou
Article Number: 209
Published online on: 23 May 2025

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Research progress in the regulatory mechanism of silent information regulator 1 in sepsis (Review)

Qilong Zhou, Weijie Gao, Weijin Zhang, Shu Tang, Hongxue Fu, Pengfei Pan
Article Number: 208
Published online on: 21 May 2025

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Retraction Open Access

[Retracted] Slit2 suppresses endothelial cell proliferation and migration by inhibiting the VEGF‑Notch signaling pathway

Guo-Jian Li, Yong Yang, Guo-Kai Yang, Jia Wan, Dao-Lei Cui, Zhen-Huan Ma, Ling-Juan Du, Gui-Min Zhang
Article Number: 207
Published online on: 20 May 2025

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METTL3‑mediated m6A methylation and its impact on OTUD1 expression in chronic obstructive pulmonary disease

Jiameng Gao, Zheyi Shen, Weibin Tian, Junyi Xia, Weixin Cao, Zhuoru Chen, Zhihua Wang, Yao Shen
Article Number: 206
Published online on: 19 May 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Article Open Access

Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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Review Open Access

T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Article Open Access

Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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