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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2013 Volume 29 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Predictive factors in patients with advanced and metastatic squamous cell carcinoma of the head and neck: A study based on SWOG protocol S0420

Smita Mehta, James Moon, Mehmood Hashmi, Michael Leblanc, Chao Hui Huang, Elizabeth Rinehart, Gregory T. Wolf, Susan G. Urba, Sushanta K. Banerjee, Stephen Williamson
Pages: 2095-2100
Published online on: 02 April 2013

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Article Open Access

Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis and cell cycle arrest in CNE-2Z nasopharyngeal carcinoma cells

Kefeng Wu, Yi Liu, Yingnian Lv, Liao Cui, Wende Li, Jianfa Chen, Nian Ci Liang, Li Li
Pages: 2101-2108
Published online on: 03 April 2013

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Article Open Access

Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway

Chan-Hun Jung, Eun Mi Kim, Jong Kuk Park, Sang-Gu Hwang, Sung-Kwon Moon, Wun-Jae Kim, Hong-Duck Um
Pages: 2109-2113
Published online on: 03 April 2013

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Article Open Access

Expression of parathyroid hormone-related protein confers malignant potential to mucoepidermoid carcinoma

Kyosuke Nagamine, Tetsuya Kitamura, Aya Yanagawa-Matsuda, Yoichi Ohiro, Kanchu Tei, Kyoko Hida, Fumihiro Higashino, Yasunori Totsuka, Masanobu Shindoh
Pages: 2114-2118
Published online on: 08 April 2013

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Article

Expression of receptor tyrosine kinases in esophageal carcinosarcoma

Akihiko Sano, Shinji Sakurai, Hiroyuki Kato, Shigemasa Suzuki, Takehiko Yokobori, Makoto Sakai, Naritaka Tanaka, Takanori Inose, Makoto Sohda, Masanobu Nakajima, Yasuyuki Fukai, Tatsuya Miyazaki, Hitoshi Ojima, Yoshinori Hosoya, Takehiko Enomoto, Tatsuo Kanda, Yoichi Ajioka, Hiroyuki Kuwano
Pages: 2119-2126
Published online on: 29 March 2013

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Article

Girdin, a regulator of cell motility, is a potential prognostic marker for esophageal squamous cell carcinoma

Takahiro Shibata, Yoichi Matsuo, Tomoya Shamoto, Takahisa  Hirokawa, Ken Tsuboi, Hiroki Takahashi, Hideyuki Ishiguro, Masahiro  Kimura, Hiromitsu Takeyama, Hiroshi Inagaki
Pages: 2127-2132
Published online on: 12 April 2013

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Article

Comparison of the bromodeoxyuridine-mediated sensitization effects between low-LET and high-LET ionizing radiation on DNA double-strand breaks

Yoshihiro Fujii, Matthew D. Genet, Erica J. Roybal, Nobuo Kubota, Ryuichi Okayasu, Kiyoshi Miyagawa, Akira Fujimori, Takamitsu A. Kato
Pages: 2133-2139
Published online on: 20 March 2013

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Article

DHL‑TauZnNa, a newly synthesized α-lipoic acid derivative, induces autophagy in human colorectal cancer cells

Takahiro Hiratsuka, Masafumi Inomata, Yohei Kono, Shigeo Yokoyama, Norio Shiraishi, Seigo Kitano
Pages: 2140-2146
Published online on: 08 April 2013

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Article

Interleukin-4 receptor α-based hybrid peptide effectively induces antitumor activity in head and neck squamous cell carcinoma

Kahori Seto, Junichi Shoda, Tomohisa Horibe, Eiji Warabi, Kazunori Ishige, Kenji Yamagata, Masayuki Kohno, Toru Yanagawa, Hiroki Bukawa, Koji Kawakami
Pages: 2147-2153
Published online on: 04 April 2013

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Article

The role of the WWOX gene in leukemia and its mechanisms of action

Zhaolei Cui, Donghong Lin, Feng Cheng, Lingqing Luo, Lingying Kong, Jianping Xu, Jianda Hu, Fenghua Lan
Pages: 2154-2162
Published online on: 22 March 2013

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Article

Cancer biomarker profiling in patients with chronic hepatitis C virus, liver cirrhosis and hepatocellular carcinoma

Susan Costantini, Francesca Capone, Patrizia Maio, Eliana Guerriero, Giovanni Colonna, Francesco Izzo, Giuseppe Castello
Pages: 2163-2168
Published online on: 03 April 2013

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Article

Downregulation of microRNA-34 induces cell proliferation and invasion of human mesothelial cells

Norimitsu Tanaka, Shinichi Toyooka, Junichi Soh, Kazunori Tsukuda, Kazuhiko Shien, Masashi Furukawa, Takayuki Muraoka, Yuho Maki, Tsuyoshi Ueno, Hiromasa Yamamoto, Hiroaki Asano, Takemi Otsuki, Shinichiro Miyoshi
Pages: 2169-2174
Published online on: 19 March 2013

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Article

Decay of γ-H2AX foci correlates with potentially lethal damage repair in prostate cancer cells

Bregje van Oorschot, Suzanne E. Hovingh, Hans Rodermond, Ahmed Güçlü, Nienke Losekoot, Albert A. Geldof, Gerrit W. Barendsen, Lukas J. Stalpers, Nicolaas A.P. Franken
Pages: 2175-2180
Published online on: 26 March 2013

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Article

Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1

Mingqiang Ren, Mei Hong, Gentao Liu, Hongjin Wang, Vijay Patel, Paul Biddinger, Jeane Silva, John Cowell, Zhonglin Hao
Pages: 2181-2190
Published online on: 04 April 2013

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Article

Downregulation of OCT4 promotes differentiation and inhibits growth of BE (2)-C human neuroblastoma I-type cells

Lin Yang, Jicui Zheng, Ting Xu, Xianmin Xiao
Pages: 2191-2196
Published online on: 21 March 2013

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Article

Combined use of adenoviral vector Ad5/F35-mediated APE1 siRNA enhances the therapeutic efficacy of adenoviral-mediated p53 gene transfer in hepatoma cells in vitro and in vivo

Yanping Cun, Qinhong Zhang, Chengjie Xiong, Mengxia Li, Nan Dai, Shiheng Zhang, Dong Wang
Pages: 2197-2204
Published online on: 04 April 2013

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Article

Tetrandrine inhibits hepatocellular carcinoma cell growth through the caspase pathway and G2/M phase

Vivian W.L. Yu, Wing Shing Ho
Pages: 2205-2210
Published online on: 20 March 2013

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Article

Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma

Kedong Xu, Jie Gao, Xue Yang, Yingmin Yao, Qingguang Liu
Pages: 2211-2218
Published online on: 26 March 2013

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Article

Christia vespertilionis plant extracts as novel antiproliferative agent against human neuroendocrine tumor cells

Daniela Hofer, Gert Schwach, Nassim Ghaffari Tabrizi-Wizsy, Anton Sadjak, Sonja Sturm, Hermann Stuppner, Roswitha Pfragner
Pages: 2219-2226
Published online on: 26 March 2013

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Article

In vitro and in vivo evaluation of anisomycin against Ehrlich ascites carcinoma

Pengtao You, Feiyue Xing, Jie Huo, Baoyu Wang, Jingfang Di, Shan Zeng, Jing Liu
Pages: 2227-2236
Published online on: 21 March 2013

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Article

Lipotropes enhance the anti-proliferative effect of chemotherapeutic drugs in MCF-7 human breast cancer cells

Kyongshin Cho, Lawrence Mabasa, Mark W. Walters, Chung S. Park
Pages: 2237-2242
Published online on: 12 April 2013

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Article

Proliferin-related protein overexpression in SGC‑7901 gastric cancer cells inhibits in vitro cell growth and tumorigenesis in nude mice

Miao He, Limin Wang, Jun Pu, Qiaozhen Yang, Gang Li, Jie Hao
Pages: 2243-2248
Published online on: 12 April 2013

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Article

Expression of hypoxia-inducible factor-1α and -2α in whole-mount prostate histology: Relation with dynamic contrast-enhanced MRI and Gleason score

Alie Borren, Greetje Groenendaal, Petra van der Groep, Maaike R. Moman, Arto E. Boeken Kruger, Uulke A. van der Heide, Trudy N. Jonges, Paul J. van Diest, Marco van Vulpen, Marielle E.P. Philippens
Pages: 2249-2254
Published online on: 08 April 2013

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Article

Quantum dot imaging for HSP70 and HSF‑1 kinetics in SCC‑25 cells with or without leucine deprivation following heat shock

Jun Chen, Jie Pan, Jianjiang Zhao, Xiaoling Qiu, Junfa Zheng, Zhiping Wang, Yuhua Huang, Hongxing Chu
Pages: 2255-2260
Published online on: 29 March 2013

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Article

Pharmacological agents with inherent anti-autophagic activity improve the cytotoxicity of imatinib

Lisa C. Crowley, Tracey R. O'Donovan, Michelle J. Nyhan, Sharon L. McKenna
Pages: 2261-2268
Published online on: 03 April 2013

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Article

All-trans retinoic acid upregulates the expression of p53 via Axin and inhibits the proliferation of glioma cells

Jianrong Lu, Feng Zhang, Yong Yuan, Caixia Ding, Liying Zhang, Qing Li
Pages: 2269-2274
Published online on: 08 April 2013

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Article

Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo Corrigendum in /10.3892/or.2024.8783

Chong Zhang, Shuang-Shuang Zhou, Xiang-Rong Li, Bao-Ming Wang, Neng-Ming Lin, Lin-Yi Feng, Da-Yong Zhang, Li-Huang Zhang, Jun-Bo Wang, Jian-Ping Pan
Pages: 2275-2282
Published online on: 12 April 2013

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Article

MGr1-Ag promotes invasion and bone metastasis of small-cell lung cancer in vitro and in vivo

Feng Zhang, Yanxia Wang, Min Xu, Haiying Dong, Na Liu, Jing Zhou, Hailin Pang, Ningqiang Ma, Ning Zhang, Yanlin Pei, Helong Zhang, Lili Liu
Pages: 2283-2290
Published online on: 09 April 2013

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Article

Leptin induces cell proliferation and reduces cell apoptosis by activating c-myc in cervical cancer

Yong Yuan, Juan Zhang, Lin Cai, Caixia Ding, Xiaomin Wang, Hongmei Chen, Xian Wang, Jun Yan, Jianrong Lu
Pages: 2291-2296
Published online on: 08 April 2013

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Article

miR-205 promotes tumor proliferation and invasion through targeting ESRRG in endometrial carcinoma

Ning Su, Haifeng Qiu, Yifei Chen, Tingting Yang, Qin Yan, Xiaoping Wan
Pages: 2297-2302
Published online on: 10 April 2013

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Article

STAT1 negatively regulates hepatocellular carcinoma cell proliferation

Guofu Chen, Haihe Wang, Shuli Xie, Jian Ma, Guangyi Wang
Pages: 2303-2310
Published online on: 09 April 2013

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Article

Anoxia/reoxygenation induces epithelial-mesenchymal transition in human colon cancer cell lines

Manabu Okajima, Satoshi Kokura, Takeshi Ishikawa, Katsura Mizushima, Reiko Tsuchiya, Tatsuzo Matsuyama, Satoko Adachi, Tetsuya Okayama, Naoyuki Sakamoto, Kazuhiro Kamada, Kazuhiro Katada, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Nobuaki Yagi, Yuji Naito, Toshikazu Yoshikawa
Pages: 2311-2317
Published online on: 10 April 2013

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Article

Downregulation of Sp1 is involved in honokiol-induced cell cycle arrest and apoptosis in human malignant pleural mesothelioma cells

Jung-Il Chae, Young-Joo Jeon, Jung-Hyun Shim
Pages: 2318-2324
Published online on: 20 March 2013

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Article

SDF-1-CXCR4 axis: Cell trafficking in the cancer stem cell niche of head and neck squamous cell carcinoma

Anne Faber, Ulrich Reinhart Goessler, Karl Hoermann, Johannes David Schultz, Claudia Umbreit, Jens Stern-Straeter
Pages: 2325-2331
Published online on: 03 April 2013

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Article

Intrapleural combination therapy with bevacizumab and cisplatin for non-small cell lung cancer‑mediated malignant pleural effusion

Nan Du, Xiaosong Li, Fang Li, Hui Zhao, Zhongyi  Fan, Junxun Ma, Yan Fu, Huanrong Kang
Pages: 2332-2340
Published online on: 15 March 2013

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Article

SZ-685C exhibits potent anticancer activity in both radiosensitive and radioresistant NPC cells through the miR-205-PTEN-Akt pathway

Dujuan Wang, Sumei Wang, Qin Liu, Mengyao Wang, Chunhua Wang, Huiling Yang
Pages: 2341-2347
Published online on: 03 April 2013

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Article

Zoledronic acid negatively affects the expansion of in vitro activated human NK cells and their cytolytic interactions with Ewing sarcoma cells

Sarah-Kristin Mueller, Bianca Altvater, Christiane Chen, Sareetha Kailayangiri, Martina Ahlmann, Uta Dirksen, Heribert Juergens, Claudia Rossig
Pages: 2348-2354
Published online on: 19 March 2013

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Article

An oncolytic herpes simplex virus vector, G47Δ, synergizes with paclitaxel in the treatment of breast cancer

Wei-Gen Zeng, Jun-Jie Li, Pan Hu, Lan Lei, Jia-Ni Wang, Ren-Bin Liu
Pages: 2355-2361
Published online on: 22 March 2013

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Article

Aquaporin 9, a promising predictor for the cytocidal effects of arsenic trioxide in acute promyelocytic leukemia cell lines and primary blasts

Noriyoshi Iriyama, Bo Yuan, Yuta Yoshino, Yoshihiro Hatta, Akira Horikoshi, Shin Aizawa, Jin Takeuchi, Hiroo Toyoda
Pages: 2362-2368
Published online on: 05 April 2013

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Article

Hypoxia of PC-3 prostate cancer cells enhances migration and vasculogenesis in vitro of bone marrow-derived endothelial progenitor cells by secretion of cytokines

Shuai Huang, Longyun Peng, Yubo Tang, Longjuan Zhang, Wei Guo, Xuenong Zou, Xinsheng Peng
Pages: 2369-2377
Published online on: 26 March 2013

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Article

c-myc but not Hif-1α-dependent downregulation of VEGF influences the proliferation and differentiation of HL-60 cells induced by ATRA

Guanhua Song, Yanmei Li, Zhiyong Zhang, Xia Ren, Hongjiang Li, Wen Zhang, Ruoying Wei, Sufei Pan, Lulu Shi, Kehong Bi, Guosheng Jiang
Pages: 2378-2384
Published online on: 09 April 2013

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Article

Enhanced radiosensitivity of NSCLC cells by transducer of erbB2.1 (TOB1) through modulation of the MAPK/ERK pathway

Ke-Kang Sun, Ning Zhong, Yang Yang, Lin Zhao, Yang Jiao
Pages: 2385-2391
Published online on: 12 April 2013

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Article

Downregulation of the GnT-V gene inhibits metastasis and invasion of BGC823 gastric cancer cells

Binbin Huang, Longe Sun, Jianchun Cao, Yunyun Zhang, Qiong Wu, Junjie Zhang, Yanli Ge, Liu Fu, Zhirong Wang
Pages: 2392-2400
Published online on: 02 April 2013

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Article

Curcumin reverses the epithelial-mesenchymal transition of pancreatic cancer cells by inhibiting the Hedgehog signaling pathway

Xiao-Dong Sun, Xing-E Liu, Dong-Sheng Huang
Pages: 2401-2407
Published online on: 04 April 2013

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Article

Angiotensin-converting enzyme 2 attenuates the metastasis of non-small cell lung cancer through inhibition of epithelial-mesenchymal transition

Yan-Rong Qian, Yi Guo, Huan-Ying Wan, Liang Fan, Yun Feng, Lei Ni, Yi Xiang, Qing-Yun Li
Pages: 2408-2414
Published online on: 29 March 2013

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Article

Changes in MYCN expression in human neuroblastoma cell lines following cisplatin treatment may not be related to MYCN copy numbers

Pavel Prochazka, Jan Hrabeta, Ales Vicha, Simon Cipro, Eva Stejskalova, Zdenek Musil, Pavel Vodicka, Tomas Eckschlager
Pages: 2415-2421
Published online on: 04 April 2013

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Article

Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth

Song Liang, Renhua Guo, Zhihong Zhang, Dongxiao Liu, Hao Xu, Zekuan Xu, Xuerong Wang, Li Yang
Pages: 2422-2430
Published online on: 09 April 2013

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Article

HSPA9 overexpression inhibits apoptin-induced apoptosis in the HepG2 cell line

Chuanmei Peng, Pu Yang, Yingbo Cui, Ming He, Leilei Liang, Yong Di
Pages: 2431-2437
Published online on: 09 April 2013

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Article

Arecoline suppresses HaCaT cell proliferation through cell cycle regulatory molecules

Zhong-Su Zhou, Ming Li, Feng Gao, Jie-Ying Peng, Hai-Bo Xiao, Li-Xia Dai, Shi-Rong Lin, Rui Zhang, Long-Yu Jin
Pages: 2438-2444
Published online on: 22 March 2013

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Article

Bilateral nerve sparing robotic-assisted radical prostatectomy is associated with faster continence recovery but not with erectile function recovery compared with retropubic open prostatectomy: The need for accurate selection of patients

Giuseppe Mario Ludovico, Giuseppe Dachille, Giovanni Pagliarulo, Carolina D'Elia, Nicola Mondaini, Mauro Gacci, Beatrice Detti, Gianni Malossini, Riccardo Bartoletti, Tommaso Cai
Pages: 2445-2450
Published online on: 26 March 2013

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Article

Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer

Lisa M. Greene, Shu Wang, Niamh M. O'Boyle, Sandra A. Bright, Jane E. Reid, Patrick Kelly, Mary J. Meegan, Daniela M. Zisterer
Pages: 2451-2458
Published online on: 03 April 2013

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Article

Effect of sarcosine on antioxidant parameters and metallothionein content in the PC-3 prostate cancer cell line

Natalia Cernei, Ondrej Zitka, Sylvie Skalickova, Jaromir Gumulec, Marketa Sztalmachova, Miguel Angel Merlos Rodrigo, Jiri Sochor, Michal Masarik, Vojtech Adam, Jaromir Hubalek, Libuse Trnkova, Jarmila Kruseova, Tomas Eckschlager, Rene Kizek
Pages: 2459-2466
Published online on: 08 April 2013

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Article

Prognostic value of changes in the expression of stem cell markers in the peripheral blood of patients with colon cancer

Maria-Elena Padín-Iruegas, Michel Herranz-Carnero, Santiago Aguin-Losada, Elena Brozos-Vazquez, U. Anido-Herranz, Jose-Ramon Antunez-Lopez, Alvaro Ruibal-Morell, Rafael López-López
Pages: 2467-2472
Published online on: 27 March 2013

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Article

Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway Retraction in /10.3892/or.2023.8691

Aiping Wang, Baochao Zhang, Jiandang Zhang, Wei Wu
Pages: 2473-2478
Published online on: 29 March 2013

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Article

Tandutinib (MLN518) reverses multidrug resistance by inhibiting the efflux activity of the multidrug resistance protein 7 (ABCC10)

Wen Deng, Chun-Ling Dai, Jun-Jiang Chen, Rishil J. Kathawala, Yue-Li Sun, Hai-Fan Chen, Li-Wu Fu, Zhe-Sheng Chen
Pages: 2479-2485
Published online on: 22 March 2013

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Combined inhibition of the EGFR and mTOR pathways in EGFR wild-type non-small cell lung cancer cell lines with different genetic backgrounds

Yu Huang, Yu Chen, Qin Mei, Yuan Chen, Shiying Yu, Shu Xia
Pages: 2486-2492
Published online on: 22 March 2013

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Article

Reduced host cell reactivation of oxidatively damaged DNA in ageing human fibroblasts

Andrew J. Rainbow, Natalie J. Zacal, Derrik M. Leach
Pages: 2493-2497
Published online on: 22 March 2013

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Article

Poly(ADP-ribose) polymerase-1 regulates the mechanism of irradiation-induced CNE-2 human nasopharyngeal carcinoma cell autophagy and inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells

Zhi-Rui Zhou, Xiao-Dong Zhu, Wei Zhao, Song Qu, Fang Su, Shi-Ting Huang, Jia-Ling Ma, Xiao-Yu Li
Pages: 2498-2506
Published online on: 04 April 2013

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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