Journal Articles

Open Access

Predictive factors in patients with advanced and metastatic squamous cell carcinoma of the head and neck: A study based on SWOG protocol S0420

Smita Mehta, James Moon, Mehmood Hashmi, Michael Leblanc, Chao Hui Huang, Elizabeth Rinehart, Gregory T. Wolf, Susan G. Urba, Sushanta K. Banerjee, Stephen Williamson

Pages: 2095-2100 Published online on: 02 April 2013
Open Access

Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis and cell cycle arrest in CNE-2Z nasopharyngeal carcinoma cells

Kefeng Wu, Yi Liu, Yingnian Lv, Liao Cui, Wende Li, Jianfa Chen, Nian Ci Liang, Li Li

Pages: 2101-2108 Published online on: 03 April 2013
Open Access

Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway

Chan-Hun Jung, Eun Mi Kim, Jong Kuk Park, Sang-Gu Hwang, Sung-Kwon Moon, Wun-Jae Kim, Hong-Duck Um

Pages: 2109-2113 Published online on: 03 April 2013
Open Access

Expression of parathyroid hormone-related protein confers malignant potential to mucoepidermoid carcinoma

Kyosuke Nagamine, Tetsuya Kitamura, Aya Yanagawa-Matsuda, Yoichi Ohiro, Kanchu Tei, Kyoko Hida, Fumihiro Higashino, Yasunori Totsuka, Masanobu Shindoh

Pages: 2114-2118 Published online on: 08 April 2013

Expression of receptor tyrosine kinases in esophageal carcinosarcoma

Akihiko Sano, Shinji Sakurai, Hiroyuki Kato, Shigemasa Suzuki, Takehiko Yokobori, Makoto Sakai, Naritaka Tanaka, Takanori Inose, Makoto Sohda, Masanobu Nakajima, Yasuyuki Fukai, Tatsuya Miyazaki, Hitoshi Ojima, Yoshinori Hosoya, Takehiko Enomoto, Tatsuo Kanda, Yoichi Ajioka, Hiroyuki Kuwano

Pages: 2119-2126 Published online on: 29 March 2013

Girdin, a regulator of cell motility, is a potential prognostic marker for esophageal squamous cell carcinoma

Takahiro Shibata, Yoichi Matsuo, Tomoya Shamoto, Takahisa  Hirokawa, Ken Tsuboi, Hiroki Takahashi, Hideyuki Ishiguro, Masahiro  Kimura, Hiromitsu Takeyama, Hiroshi Inagaki

Pages: 2127-2132 Published online on: 12 April 2013

Comparison of the bromodeoxyuridine-mediated sensitization effects between low-LET and high-LET ionizing radiation on DNA double-strand breaks

Yoshihiro Fujii, Matthew D. Genet, Erica J. Roybal, Nobuo Kubota, Ryuichi Okayasu, Kiyoshi Miyagawa, Akira Fujimori, Takamitsu A. Kato

Pages: 2133-2139 Published online on: 20 March 2013

DHL‑TauZnNa, a newly synthesized α-lipoic acid derivative, induces autophagy in human colorectal cancer cells

Takahiro Hiratsuka, Masafumi Inomata, Yohei Kono, Shigeo Yokoyama, Norio Shiraishi, Seigo Kitano

Pages: 2140-2146 Published online on: 08 April 2013

Interleukin-4 receptor α-based hybrid peptide effectively induces antitumor activity in head and neck squamous cell carcinoma

Kahori Seto, Junichi Shoda, Tomohisa Horibe, Eiji Warabi, Kazunori Ishige, Kenji Yamagata, Masayuki Kohno, Toru Yanagawa, Hiroki Bukawa, Koji Kawakami

Pages: 2147-2153 Published online on: 04 April 2013

The role of the WWOX gene in leukemia and its mechanisms of action

Zhaolei Cui, Donghong Lin, Feng Cheng, Lingqing Luo, Lingying Kong, Jianping Xu, Jianda Hu, Fenghua Lan

Pages: 2154-2162 Published online on: 22 March 2013

Cancer biomarker profiling in patients with chronic hepatitis C virus, liver cirrhosis and hepatocellular carcinoma

Susan Costantini, Francesca Capone, Patrizia Maio, Eliana Guerriero, Giovanni Colonna, Francesco Izzo, Giuseppe Castello

Pages: 2163-2168 Published online on: 03 April 2013

Downregulation of microRNA-34 induces cell proliferation and invasion of human mesothelial cells

Norimitsu Tanaka, Shinichi Toyooka, Junichi Soh, Kazunori Tsukuda, Kazuhiko Shien, Masashi Furukawa, Takayuki Muraoka, Yuho Maki, Tsuyoshi Ueno, Hiromasa Yamamoto, Hiroaki Asano, Takemi Otsuki, Shinichiro Miyoshi

Pages: 2169-2174 Published online on: 19 March 2013

Decay of γ-H2AX foci correlates with potentially lethal damage repair in prostate cancer cells

Bregje van Oorschot, Suzanne E. Hovingh, Hans Rodermond, Ahmed Güçlü, Nienke Losekoot, Albert A. Geldof, Gerrit W. Barendsen, Lukas J. Stalpers, Nicolaas A.P. Franken

Pages: 2175-2180 Published online on: 26 March 2013

Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1

Mingqiang Ren, Mei Hong, Gentao Liu, Hongjin Wang, Vijay Patel, Paul Biddinger, Jeane Silva, John Cowell, Zhonglin Hao

Pages: 2181-2190 Published online on: 04 April 2013

Downregulation of OCT4 promotes differentiation and inhibits growth of BE (2)-C human neuroblastoma I-type cells

Lin Yang, Jicui Zheng, Ting Xu, Xianmin Xiao

Pages: 2191-2196 Published online on: 21 March 2013

Combined use of adenoviral vector Ad5/F35-mediated APE1 siRNA enhances the therapeutic efficacy of adenoviral-mediated p53 gene transfer in hepatoma cells in vitro and in vivo

Yanping Cun, Qinhong Zhang, Chengjie Xiong, Mengxia Li, Nan Dai, Shiheng Zhang, Dong Wang

Pages: 2197-2204 Published online on: 04 April 2013

Tetrandrine inhibits hepatocellular carcinoma cell growth through the caspase pathway and G2/M phase

Vivian W.L. Yu, Wing Shing Ho

Pages: 2205-2210 Published online on: 20 March 2013

Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma

Kedong Xu, Jie Gao, Xue Yang, Yingmin Yao, Qingguang Liu

Pages: 2211-2218 Published online on: 26 March 2013

Christia vespertilionis plant extracts as novel antiproliferative agent against human neuroendocrine tumor cells

Daniela Hofer, Gert Schwach, Nassim Ghaffari Tabrizi-Wizsy, Anton Sadjak, Sonja Sturm, Hermann Stuppner, Roswitha Pfragner

Pages: 2219-2226 Published online on: 26 March 2013

In vitro and in vivo evaluation of anisomycin against Ehrlich ascites carcinoma

Pengtao You, Feiyue Xing, Jie Huo, Baoyu Wang, Jingfang Di, Shan Zeng, Jing Liu

Pages: 2227-2236 Published online on: 21 March 2013

Lipotropes enhance the anti-proliferative effect of chemotherapeutic drugs in MCF-7 human breast cancer cells

Kyongshin Cho, Lawrence Mabasa, Mark W. Walters, Chung S. Park

Pages: 2237-2242 Published online on: 12 April 2013

Proliferin-related protein overexpression in SGC‑7901 gastric cancer cells inhibits in vitro cell growth and tumorigenesis in nude mice

Miao He, Limin Wang, Jun Pu, Qiaozhen Yang, Gang Li, Jie Hao

Pages: 2243-2248 Published online on: 12 April 2013

Expression of hypoxia-inducible factor-1α and -2α in whole-mount prostate histology: Relation with dynamic contrast-enhanced MRI and Gleason score

Alie Borren, Greetje Groenendaal, Petra van der Groep, Maaike R. Moman, Arto E. Boeken Kruger, Uulke A. van der Heide, Trudy N. Jonges, Paul J. van Diest, Marco van Vulpen, Marielle E.P. Philippens

Pages: 2249-2254 Published online on: 08 April 2013

Quantum dot imaging for HSP70 and HSF‑1 kinetics in SCC‑25 cells with or without leucine deprivation following heat shock

Jun Chen, Jie Pan, Jianjiang Zhao, Xiaoling Qiu, Junfa Zheng, Zhiping Wang, Yuhua Huang, Hongxing Chu

Pages: 2255-2260 Published online on: 29 March 2013

Pharmacological agents with inherent anti-autophagic activity improve the cytotoxicity of imatinib

Lisa C. Crowley, Tracey R. O'Donovan, Michelle J. Nyhan, Sharon L. McKenna

Pages: 2261-2268 Published online on: 03 April 2013

All-trans retinoic acid upregulates the expression of p53 via Axin and inhibits the proliferation of glioma cells

Jianrong Lu, Feng Zhang, Yong Yuan, Caixia Ding, Liying Zhang, Qing Li

Pages: 2269-2274 Published online on: 08 April 2013

Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo

Chong Zhang, Shuang-Shuang Zhou, Xiang-Rong Li, Bao-Ming Wang, Neng-Ming Lin, Lin-Yi Feng, Da-Yong Zhang, Li-Huang Zhang, Jun-Bo Wang, Jian-Ping Pan

Pages: 2275-2282 Published online on: 12 April 2013

MGr1-Ag promotes invasion and bone metastasis of small-cell lung cancer in vitro and in vivo

Feng Zhang, Yanxia Wang, Min Xu, Haiying Dong, Na Liu, Jing Zhou, Hailin Pang, Ningqiang Ma, Ning Zhang, Yanlin Pei, Helong Zhang, Lili Liu

Pages: 2283-2290 Published online on: 09 April 2013

Leptin induces cell proliferation and reduces cell apoptosis by activating c-myc in cervical cancer

Yong Yuan, Juan Zhang, Lin Cai, Caixia Ding, Xiaomin Wang, Hongmei Chen, Xian Wang, Jun Yan, Jianrong Lu

Pages: 2291-2296 Published online on: 08 April 2013

miR-205 promotes tumor proliferation and invasion through targeting ESRRG in endometrial carcinoma

Ning Su, Haifeng Qiu, Yifei Chen, Tingting Yang, Qin Yan, Xiaoping Wan

Pages: 2297-2302 Published online on: 10 April 2013

STAT1 negatively regulates hepatocellular carcinoma cell proliferation

Guofu Chen, Haihe Wang, Shuli Xie, Jian Ma, Guangyi Wang

Pages: 2303-2310 Published online on: 09 April 2013

Anoxia/reoxygenation induces epithelial-mesenchymal transition in human colon cancer cell lines

Manabu Okajima, Satoshi Kokura, Takeshi Ishikawa, Katsura Mizushima, Reiko Tsuchiya, Tatsuzo Matsuyama, Satoko Adachi, Tetsuya Okayama, Naoyuki Sakamoto, Kazuhiro Kamada, Kazuhiro Katada, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Nobuaki Yagi, Yuji Naito, Toshikazu Yoshikawa

Pages: 2311-2317 Published online on: 10 April 2013

Downregulation of Sp1 is involved in honokiol-induced cell cycle arrest and apoptosis in human malignant pleural mesothelioma cells

Jung-Il Chae, Young-Joo Jeon, Jung-Hyun Shim

Pages: 2318-2324 Published online on: 20 March 2013

SDF-1-CXCR4 axis: Cell trafficking in the cancer stem cell niche of head and neck squamous cell carcinoma

Anne Faber, Ulrich Reinhart Goessler, Karl Hoermann, Johannes David Schultz, Claudia Umbreit, Jens Stern-Straeter

Pages: 2325-2331 Published online on: 03 April 2013

Intrapleural combination therapy with bevacizumab and cisplatin for non-small cell lung cancer‑mediated malignant pleural effusion

Nan Du, Xiaosong Li, Fang Li, Hui Zhao, Zhongyi  Fan, Junxun Ma, Yan Fu, Huanrong Kang

Pages: 2332-2340 Published online on: 15 March 2013

SZ-685C exhibits potent anticancer activity in both radiosensitive and radioresistant NPC cells through the miR-205-PTEN-Akt pathway

Dujuan Wang, Sumei Wang, Qin Liu, Mengyao Wang, Chunhua Wang, Huiling Yang

Pages: 2341-2347 Published online on: 03 April 2013

Zoledronic acid negatively affects the expansion of in vitro activated human NK cells and their cytolytic interactions with Ewing sarcoma cells

Sarah-Kristin Mueller, Bianca Altvater, Christiane Chen, Sareetha Kailayangiri, Martina Ahlmann, Uta Dirksen, Heribert Juergens, Claudia Rossig

Pages: 2348-2354 Published online on: 19 March 2013

An oncolytic herpes simplex virus vector, G47Δ, synergizes with paclitaxel in the treatment of breast cancer

Wei-Gen Zeng, Jun-Jie Li, Pan Hu, Lan Lei, Jia-Ni Wang, Ren-Bin Liu

Pages: 2355-2361 Published online on: 22 March 2013

Aquaporin 9, a promising predictor for the cytocidal effects of arsenic trioxide in acute promyelocytic leukemia cell lines and primary blasts

Noriyoshi Iriyama, Bo Yuan, Yuta Yoshino, Yoshihiro Hatta, Akira Horikoshi, Shin Aizawa, Jin Takeuchi, Hiroo Toyoda

Pages: 2362-2368 Published online on: 05 April 2013

Hypoxia of PC-3 prostate cancer cells enhances migration and vasculogenesis in vitro of bone marrow-derived endothelial progenitor cells by secretion of cytokines

Shuai Huang, Longyun Peng, Yubo Tang, Longjuan Zhang, Wei Guo, Xuenong Zou, Xinsheng Peng

Pages: 2369-2377 Published online on: 26 March 2013

c-myc but not Hif-1α-dependent downregulation of VEGF influences the proliferation and differentiation of HL-60 cells induced by ATRA

Guanhua Song, Yanmei Li, Zhiyong Zhang, Xia Ren, Hongjiang Li, Wen Zhang, Ruoying Wei, Sufei Pan, Lulu Shi, Kehong Bi, Guosheng Jiang

Pages: 2378-2384 Published online on: 09 April 2013

Enhanced radiosensitivity of NSCLC cells by transducer of erbB2.1 (TOB1) through modulation of the MAPK/ERK pathway

Ke-Kang Sun, Ning Zhong, Yang Yang, Lin Zhao, Yang Jiao

Pages: 2385-2391 Published online on: 12 April 2013

Downregulation of the GnT-V gene inhibits metastasis and invasion of BGC823 gastric cancer cells

Binbin Huang, Longe Sun, Jianchun Cao, Yunyun Zhang, Qiong Wu, Junjie Zhang, Yanli Ge, Liu Fu, Zhirong Wang

Pages: 2392-2400 Published online on: 02 April 2013

Curcumin reverses the epithelial-mesenchymal transition of pancreatic cancer cells by inhibiting the Hedgehog signaling pathway

Xiao-Dong Sun, Xing-E Liu, Dong-Sheng Huang

Pages: 2401-2407 Published online on: 04 April 2013

Angiotensin-converting enzyme 2 attenuates the metastasis of non-small cell lung cancer through inhibition of epithelial-mesenchymal transition

Yan-Rong Qian, Yi Guo, Huan-Ying Wan, Liang Fan, Yun Feng, Lei Ni, Yi Xiang, Qing-Yun Li

Pages: 2408-2414 Published online on: 29 March 2013

Changes in MYCN expression in human neuroblastoma cell lines following cisplatin treatment may not be related to MYCN copy numbers

Pavel Prochazka, Jan Hrabeta, Ales Vicha, Simon Cipro, Eva Stejskalova, Zdenek Musil, Pavel Vodicka, Tomas Eckschlager

Pages: 2415-2421 Published online on: 04 April 2013

Upregulation of the eIF4E signaling pathway contributes to the progression of gastric cancer, and targeting eIF4E by perifosine inhibits cell growth

Song Liang, Renhua Guo, Zhihong Zhang, Dongxiao Liu, Hao Xu, Zekuan Xu, Xuerong Wang, Li Yang

Pages: 2422-2430 Published online on: 09 April 2013

HSPA9 overexpression inhibits apoptin-induced apoptosis in the HepG2 cell line

Chuanmei Peng, Pu Yang, Yingbo Cui, Ming He, Leilei Liang, Yong Di

Pages: 2431-2437 Published online on: 09 April 2013

Arecoline suppresses HaCaT cell proliferation through cell cycle regulatory molecules

Zhong-Su Zhou, Ming Li, Feng Gao, Jie-Ying Peng, Hai-Bo Xiao, Li-Xia Dai, Shi-Rong Lin, Rui Zhang, Long-Yu Jin

Pages: 2438-2444 Published online on: 22 March 2013

Bilateral nerve sparing robotic-assisted radical prostatectomy is associated with faster continence recovery but not with erectile function recovery compared with retropubic open prostatectomy: The need for accurate selection of patients

Giuseppe Mario Ludovico, Giuseppe Dachille, Giovanni Pagliarulo, Carolina D'Elia, Nicola Mondaini, Mauro Gacci, Beatrice Detti, Gianni Malossini, Riccardo Bartoletti, Tommaso Cai

Pages: 2445-2450 Published online on: 26 March 2013

Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer

Lisa M. Greene, Shu Wang, Niamh M. O'Boyle, Sandra A. Bright, Jane E. Reid, Patrick Kelly, Mary J. Meegan, Daniela M. Zisterer

Pages: 2451-2458 Published online on: 03 April 2013

Effect of sarcosine on antioxidant parameters and metallothionein content in the PC-3 prostate cancer cell line

Natalia Cernei, Ondrej Zitka, Sylvie Skalickova, Jaromir Gumulec, Marketa Sztalmachova, Miguel Angel Merlos Rodrigo, Jiri Sochor, Michal Masarik, Vojtech Adam, Jaromir Hubalek, Libuse Trnkova, Jarmila Kruseova, Tomas Eckschlager, Rene Kizek

Pages: 2459-2466 Published online on: 08 April 2013

Prognostic value of changes in the expression of stem cell markers in the peripheral blood of patients with colon cancer

Maria-Elena Padín-Iruegas, Michel Herranz-Carnero, Santiago Aguin-Losada, Elena Brozos-Vazquez, U. Anido-Herranz, Jose-Ramon Antunez-Lopez, Alvaro Ruibal-Morell, Rafael López-López

Pages: 2467-2472 Published online on: 27 March 2013

Embelin-induced brain glioma cell apoptosis and cell cycle arrest via the mitochondrial pathway

Aiping Wang, Baochao Zhang, Jiandang Zhang, Wei Wu

Pages: 2473-2478 Published online on: 29 March 2013

Tandutinib (MLN518) reverses multidrug resistance by inhibiting the efflux activity of the multidrug resistance protein 7 (ABCC10)

Wen Deng, Chun-Ling Dai, Jun-Jiang Chen, Rishil J. Kathawala, Yue-Li Sun, Hai-Fan Chen, Li-Wu Fu, Zhe-Sheng Chen

Pages: 2479-2485 Published online on: 22 March 2013

Combined inhibition of the EGFR and mTOR pathways in EGFR wild-type non-small cell lung cancer cell lines with different genetic backgrounds

Yu Huang, Yu Chen, Qin Mei, Yuan Chen, Shiying Yu, Shu Xia

Pages: 2486-2492 Published online on: 22 March 2013

Reduced host cell reactivation of oxidatively damaged DNA in ageing human fibroblasts

Andrew J. Rainbow, Natalie J. Zacal, Derrik M. Leach

Pages: 2493-2497 Published online on: 22 March 2013

Poly(ADP-ribose) polymerase-1 regulates the mechanism of irradiation-induced CNE-2 human nasopharyngeal carcinoma cell autophagy and inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells

Zhi-Rui Zhou, Xiao-Dong Zhu, Wei Zhao, Song Qu, Fang Su, Shi-Ting Huang, Jia-Ling Ma, Xiao-Yu Li

Pages: 2498-2506 Published online on: 04 April 2013
Journal Cover

June 2013
Volume 29 Issue 6

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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