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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2014 Volume 32 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Targeting the NF-E2-related factor 2 pathway: A novel strategy for glioblastoma (Review)

Jianhong Zhu, Handong Wang, Youwu Fan, Yixing Lin, Li  Zhang, Xiangjun Ji, Mengliang Zhou
Pages: 443-450
Published online on: 12 June 2014

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Review

Clinical evidence of the relationship between aspirin and breast cancer risk (Review)

Nadia J. Jacobo-Herrera, Carlos Pérez-Plasencia, Elizabeth  Camacho‑Zavala, Gabriela Figueroa González, Eduardo López Urrutia, Verónica  García‑Castillo, Alejandro Zentella-Dehesa
Pages: 451-451
Published online on: 13 June 2014

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Article Open Access

hBD-2 is downregulated in oral carcinoma cells by DNA hypermethylation, and increased expression of hBD-2 by DNA demethylation and gene transfection inhibits cell proliferation and invasion

Yoshitaka Kamino, Yoshihito Kurashige, Osamu Uehara, Jun Sato, Michiko Nishimura, Koki Yoshida, Toshiya Arakawa, Hiroki Nagayasu, Masato Saitoh, Yoshihiro Abiko
Pages: 462-468
Published online on: 12 June 2014

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Article Open Access

Gli1 contributes to cellular resistance to cisplatin through altered cellular accumulation of the drug

Lauren Amable, Jason Fain, Elaine Gavin, Eddie Reed
Pages: 469-474
Published online on: 12 June 2014

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Article Open Access

Combined effects of asbestos and cigarette smoke on the development of lung adenocarcinoma: Different carcinogens may cause different genomic changes

Kentaro Inamura, Hironori Ninomiya, Kimie  Nomura, Eiju  Tsuchiya, Yukitoshi  Satoh, Sakae  Okumura, Ken  Nakagawa, Ayako  Takata, Norihiko  Kohyama, Yuichi  Ishikawa
Pages: 475-482
Published online on: 13 June 2014

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Article Open Access

Genomic characterization of ependymomas reveals 6q loss as the most common aberration

Thale Kristin Olsen, Ludmila Gorunova, Torstein R. Meling, Francesca Micci, David Scheie, Bernt Due-Tønnessen, Sverre Heim, Petter Brandal
Pages: 483-490
Published online on: 16 June 2014

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Article Open Access

Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment

Magdalena Milczarek, Beata Filip-Psurska, Wiesław Świętnicki, Andrzej Kutner, Joanna Wietrzyk
Pages: 491-504
Published online on: 11 June 2014

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Article Open Access

Differential promoter methylation of kinesin family member 1a in plasma is associated with breast cancer and DNA repair capacity

Rafael Guerrero-Preston, Tal  Hadar, Kimberly  Laskie Ostrow, Ethan  Soudry, Miguel  Echenique, Carmen  Ili-Gangas, Gabriela  Pérez, Jimena  Perez, Priscilla  Brebi-Mieville, José  Deschamps, Luisa  Morales, Manuel  Bayona, David  Sidransky, Jaime  Matta
Pages: 505-512
Published online on: 13 June 2014

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Article Open Access

PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin

Meng-Yao Wu, Xin Xie, Ze-Kuan Xu, Li Xie, Zheng Chen, Liu‑Mei  Shou, Fei-Ran Gong, Yu-Feng Xie, Wei Li, Min Tao
Pages: 513-522
Published online on: 13 June 2014

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Article Open Access

Involvement of macrophage migration inhibitory factor and its receptor (CD74) in human breast cancer

Vincent Richard, Nadège Kindt, Christine Decaestecker, Hans‑Joachim Gabius, Guy Laurent, Jean-Christophe Noël, Sven Saussez
Pages: 523-529
Published online on: 16 June 2014

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Article

Prognostic factors in Epstein-Barr virus-associated stage I-III gastric carcinoma: Implications for a unique type of carcinogenesis

Shih-Chiang Huang, Kwai-Fong Ng, Kuang-Hua  Chen, Jun‑Te  Hsu, Keng-Hao Liu, Ta-Sen  Yeh, Tse-Ching  Chen
Pages: 530-538
Published online on: 05 June 2014

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Article

Fusion of HepG2 cells with mesenchymal stem cells increases cancer‑associated and malignant properties: An in vivo metastasis model

Hong Li, Zhenqing Feng, Tom C. Tsang, Tian  Tang, Xiaoqin  Jia, Xianghui  He, Michael  E. Pennington, Michael  S. Badowski, Anna  K.M. Liu, Deyu  Chen, David  T. Harris, Jesse  Martinez, Linda  C. Meade-Tollin
Pages: 539-547
Published online on: 13 June 2014

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Article

A single nucleotide polymorphism in fibronectin 1 determines tumor shape in colorectal cancer

Hiroyuki Kida, Yuki Takano, Ken  Yamamoto, Masaki  Mori, Katsuhiko  Yanaga, Jun-Ichi  Tanaka, Shin-Ei  Kudo, Koshi  Mimori
Pages: 548-552
Published online on: 12 June 2014

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Article

The PI3K/mTOR dual inhibitor NVP-BEZ235 reduces the growth of ovarian clear cell carcinoma

Tetsuro Oishi, Hiroaki Itamochi, Akiko Kudoh, Michiko Nonaka, Misaki Kato, Mayumi Nishimura, Nao Oumi, Seiya Sato, Jun Naniwa, Shinya Sato, Muneaki Shimada, Junzo Kigawa, Tasuku Harada
Pages: 553-558
Published online on: 13 June 2014

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Article

Blocking PI3K/Akt signaling attenuates metastasis of nasopharyngeal carcinoma cells through induction of mesenchymal-epithelial reverting transition

Hanguo Jiang, Mei Gao, Zhihua Shen, Botao  Luo, Rujia  Li, Xiaofan  Jiang, Ranran  Ding, Yanping  Ha, Zhenliang Wang, Wei  Jie
Pages: 559-566
Published online on: 29 May 2014

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Article

Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways

Jia Liu, Lanhong Zheng, Jiateng Zhong, Ning Wu, Ge Liu, Xiukun Lin
Pages: 567-572
Published online on: 06 June 2014

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Article

Plasmid-based Stat3-specific siRNA and GRIM-19 inhibit the growth of thyroid cancer cells in vitro and in vivo

Gui-Min Wang, Zhong-Xi Ren, Pei-Song Wang, Chang Su, Wen-Xin Zhang, Zeng-Guang Liu, Ling Zhang, Xue-Jian Zhao, Guang Chen
Pages: 573-580
Published online on: 05 June 2014

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Article

Reduced BMP6 expression by DNA methylation contributes to EMT and drug resistance in breast cancer cells

Geng Liu, Yuan-Jie Liu, Wen-Jing Lian, Zhi-Wei Zhao, Tao Yi, Hong-Ying Zhou
Pages: 581-588
Published online on: 29 May 2014

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Article

miR-5000-3p, miR-5009-3P and miR-552: Potential microRNA biomarkers of side population cells in colon cancer

Zhong-Sheng Xia, Lin Wang, Tao Yu, Wa Zhong, Guo-Da Lian, Di Wu, Hui-Min Zhou, Guang-Cheng Chen
Pages: 589-596
Published online on: 04 June 2014

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Article

Quinazoline analog HMJ-30 inhibits angiogenesis: Involvement of endothelial cell apoptosis through ROS-JNK-mediated death receptor 5 signaling

Chi-Cheng Lu, Hao-Ping Chen, Jo-Hua Chiang, Yi-An Jin, Sheng-Chu Kuo, Tian-Shung Wu, Mann-Jen Hour, Jai-Sing Yang, Yu-Jen Chiu
Pages: 597-606
Published online on: 12 June 2014

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Article

Overexpression of Tiam1 is associated with malignant phenotypes of nasopharyngeal carcinoma

Yi Ding, Bin Chen, Jing Huang, Wenli Zhang, Hongjun Yang, Yongjian Deng, Jie Lin, Shuang Wang, Xiangmei Zhang
Pages: 607-618
Published online on: 06 June 2014

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Article

Involvement of Drp1 in hypoxia-induced migration of human glioblastoma U251 cells

Yu-Ying Wan, Jian-Feng Zhang, Zhang-Jian  Yang, Li-Ping  Jiang, Yong‑Fang  Wei, Qi-Nan  Lai, Jian-Bin  Wang, Hong-Bo Xin, Xiao-Jian Han
Pages: 619-626
Published online on: 05 June 2014

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Article

A771726, an anti-inflammatory drug, exerts an anticancer effect and reverses tamoxifen resistance in endocrine‑resistant breast cancer cells

Ou Huang, Zuoquan Xie, Weili  Zhang, Ying  Lou, Yan  Mao, Hongchun Liu, Min Jiang, Kunwei Shen
Pages: 627-634
Published online on: 12 June 2014

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Article

Effect of brachytherapy on NF-κB and VEGF in gastric carcinoma xenografts

Wan-Fu Zhang, Wen-Di Jin, Bo Li, Ming-Chun Wang, Xiao-Gang Li, Wen-Yuan Mao, Kai-Yuan Luo
Pages: 635-640
Published online on: 12 June 2014

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Article

Cancer stem cell differentiation: TGFβ1 and versican may trigger molecules for the organization of tumor spheroids

G.  Oktem, O.  Sercan, U.  Guven, R.  Uslu, A.  Uysal, G.  Goksel, S.  Ayla, A.  Bilir
Pages: 641-649
Published online on: 12 June 2014

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Article

Ad-endostatin treatment combined with low-dose irradiation in a murine lung cancer model

Xiao-Peng Li, Hai-Long Zhang, Hui-Juan Wang, Yong-Xia Li, Meng Li, Lian Lu, Yang Wan, Bai-Ling Zhou, Yan Liu, Ying Pan, Xiao-Zhe Wu, Ying-Zi Fan, Chao-Heng Yu, Yu-Quan Wei, Hua-Shan Shi
Pages: 650-658
Published online on: 12 June 2014

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Article

The dineolignan from Saururus chinensis, manassantin B, inhibits tumor-induced angiogenesis via downregulation of matrix metalloproteinases 9 in human endothelial cells

Zhaojie Liu, Hong Lu, Rong  Liu, Bin  Chen, Shan  Wang, Junchao  Ma, Jianjiang  Fu
Pages: 659-667
Published online on: 11 June 2014

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Article

Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro

Claudia Umbreit, Christoph Aderhold, Anne Faber, Alexander Sauter, Ralf-Dieter Hofheinz, Jens Stern-Straeter, Karl Hoermann, Johannes David Schultz
Pages: 668-676
Published online on: 30 May 2014

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Article

CD166 plays a pro-carcinogenic role in liver cancer cells via inhibition of FOXO proteins through AKT

Wenjun Yu, Jiayi Wang, Lifang Ma, Xun Tang, Yongxia Qiao, Quihui Pan, Yongchun Yu, Fenyong Sun
Pages: 677-683
Published online on: 30 May 2014

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Article

Establishment of NOD/SCID mouse model of central nervous system leukemia

Dongfang Li, Pinggan Li, Zhanwen He, Zhe Meng, Xiangyang Luo, Jianpei Fang
Pages: 684-690
Published online on: 12 June 2014

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Article

Using [18F]FBAU for imaging brain tumor progression in an F98/tk-luc glioma-bearing rat model

Yi-Chun Chien, John Chun-Hao Chen, Wei-Chan Lin, Hueisch-Jy Ding, Hsin-Ell Wang, Chih-Hao K. Kao, Jeng-Jong Hwang
Pages: 691-699
Published online on: 12 June 2014

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Article

Characterization of EGFR family gene aberrations in cholangiocarcinoma

Xiaoqing Yang, Weishan Wang, Chunni Wang, Lin Wang, Muyi Yang, Mei Qi, Hong Su, Xiubin Sun, Zhiyan Liu, Juan Zhang, Xiaomin Qin, Bo Han
Pages: 700-708
Published online on: 13 June 2014

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Article

In vivo assessment of the vascular disrupting effect of M410 by DCE-MRI biomarker in a rabbit model of liver tumor

Rui-Meng Yang, Yong Zou, Dan-Ping  Huang, Sheng‑Sheng  Lai, Xiang‑Dong Xu, Xin‑Hua  Wei, Han-Zheng Chang, Tong‑Kun  Huang, Li  Wang, Wen-Jie  Tang, Xin-Qing Jiang
Pages: 709-715
Published online on: 04 June 2014

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Article

Norcantharidin enhances ABT-263-mediated anticancer activity in neuroblastoma cells by upregulation of Noxa

Xiaohui Wang, Zhimin Gu, Gongquan Li, Shufeng Zhang, Zhenjie Cao, Zhanfeng Yang, Guangzhi Liu
Pages: 716-722
Published online on: 30 May 2014

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Article

Hypoxia-targeted triple suicide gene therapy radiosensitizes human colorectal cancer cells

Hung Tsung Hsiao, Ligang Xing, Xuelong Deng, Xiaorong Sun, C. Clifton Ling, Gloria C. Li
Pages: 723-729
Published online on: 06 June 2014

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Article

Elevated expression of the nuclear export protein, Crm1 (exportin 1), associates with human oesophageal squamous cell carcinoma

Pauline J. van der Watt, Widaad Zemanay, Dhirendra Govender, Denver T. Hendricks, M. I. Parker, Virna D. Leaner
Pages: 730-738
Published online on: 04 June 2014

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Article

Gene expression profiling of HL-60 cells following knockdown of nucleostemin using DNA microarrays

Xiaoli Sun, Yu Jia, Yuanyu Wei, Shuai Liu, Baohong Yue
Pages: 739-747
Published online on: 06 June 2014

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Article

Overexpression of flotillin-1 is involved in proliferation and recurrence of bladder transitional cell carcinoma

Yawei Guan, Haiyan Song, Guohui Zhang, Xing Ai
Pages: 748-754
Published online on: 29 May 2014

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Article

Co-expression of CD133, CD44v6 and human tissue factor is associated with metastasis and poor prognosis in pancreatic carcinoma

Kai Chen, Zhonghu Li, Peng Jiang, Xi Zhang, Yujun Zhang, Yan Jiang, Yu He, Xiaowu Li
Pages: 755-763
Published online on: 11 June 2014

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Article

shRNA targeting Bmi-1 sensitizes CD44+ nasopharyngeal cancer stem-like cells to radiotherapy

Xin-Hua Xu, Xiao-Yan Liu, Jin Su, Dao-Jun  Li, Qiao  Huang, Ming‑Qian  Lu, Fang  Yi, Jing-Hua  Ren, Wei-Hong Chen
Pages: 764-770
Published online on: 13 June 2014

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Article

Wnt5a promotes vasculogenic mimicry and epithelial-mesenchymal transition via protein kinase Cα in epithelial ovarian cancer

Hong Qi, Baocun Sun, Xiulan  Zhao, Jing  Du, Qiang  Gu, Yanrong  Liu, Runfen  Cheng, Xueyi  Dong
Pages: 771-779
Published online on: 04 June 2014

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Article

Resistance of oral squamous cell carcinoma cells to cetuximab is associated with EGFR insensitivity and enhanced stem cell-like potency

Yuichi Ohnishi, Yuki Minamino, Kenji  Kakudo, Masami Nozaki
Pages: 780-786
Published online on: 12 June 2014

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Article

Modulation of microRNAs by ionizing radiation in human gastric cancer

Jinpeng He, Junrui Hua, Nan Ding, Shuai Xu, Rui Sun, Guangming Zhou, Xiaodong Xie, Jufang Wang
Pages: 787-793
Published online on: 11 June 2014

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Article

Chemokine receptor 7 enhances cell chemotaxis and migration of metastatic squamous cell carcinoma of head and neck through activation of matrix metalloproteinase-9

Nan Guo, Fayu Liu, Liangliang Yang, Jinying Huang, Xue Ding, Changfu Sun
Pages: 794-800
Published online on: 06 June 2014

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Article

Nuclear expression of p53 in mature tumor endothelium of retinoblastoma

Byung Joo Lee, Jin Hyoung Kim, Dong  Hyun Jo, Kyu‑Won  Kim, Young   Suk Yu, Jeong Hun Kim
Pages: 801-807
Published online on: 05 June 2014

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Article

Younger age at the time of first metastasis in BRAF-mutated compared to BRAF wild-type melanoma patients

Melanie Saint-Jean, Gaëlle Quereux, Jean-Michel Nguyen, Lucie Peuvrel, Anabelle Brocard, Audrey Vallee, Anne-Chantal Knol, Amir Khammari, Marc G. Denis, Brigitte Dréno
Pages: 808-814
Published online on: 13 June 2014

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Article

Aberrant hypomethylation-mediated AGR2 overexpression induces an aggressive phenotype in ovarian cancer cells

Hye Youn Sung, Eun Nam Choi, Dahyun Lyu, Ae Kyung Park, Woong Ju, Jung-Hyuck Ahn
Pages: 815-820
Published online on: 11 June 2014

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Article

Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase

Juthika Kundu, Bu Young Choi, Chul-Ho Jeong, Joydeb Kumar Kundu, Kyung-Soo Chun
Pages: 821-828
Published online on: 29 May 2014

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Article

Cholangiocarcinoma cell line TK may be useful for the pharmacokinetic study of the chemotherapeutic agent gemcitabine

Minori Kamada, Kohei Akiyoshi, Nobutake Akiyama, Naotake Funamizu, Michiko Watanabe, Kouki Fujioka, Kei-Ichi Ikeda, Yoshinobu Manome
Pages: 829-834
Published online on: 30 May 2014

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Article

Minocycline and cisplatin exert synergistic growth suppression on hepatocellular carcinoma by inducing S phase arrest and apoptosis

Fu-Yao Liu, Yan-Hui Wu, Shao-Jun Zhou, Yue-Ling Deng, Zun‑Yi  Zhang, Er-Lei Zhang, Zhi-Yong Huang
Pages: 835-844
Published online on: 12 June 2014

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Article

Anchorage-independent growth of Ewing sarcoma cells under serum-free conditions is not associated with stem-cell like phenotype and function

Katharina Leuchte, Bianca Altvater, Simeon  Hoffschlag, Jenny  Potratz, Jutta  Meltzer, Dagmar Clemens, Andrea  Luecke, Jendrik  Hardes, Uta  Dirksen, Heribert  Juergens, Sareetha Kailayangiri, Claudia  Rossig
Pages: 845-852
Published online on: 13 June 2014

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Article

Asparagine synthetase expression and its potential prognostic value in patients with NK/T cell lymphoma

Yaqing Li, Xudong Zhang, Tengpeng Hu, Lijuan Han, Ruping Li, Jianguo Wen, Mingzhi Zhang
Pages: 853-859
Published online on: 06 June 2014

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Article

Identity-by-descent approaches identify regions of importance for genetic susceptibility to hereditary esophageal squamous cell carcinoma

Josephine My Ko, Peng Zhang, Simon Law, Yanhui Fan, You-Qiang Song, Xue Ke Zhao, Elibe H.W. Wong, Sa Tang, Xin Song, Maria Li Lung, Li Dong Wang
Pages: 860-870
Published online on: 29 May 2014

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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