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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2016 Volume 35 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

The emerging role of RUNX3 in cancer metastasis (Review)

Feifei Chen, Xin Liu, Jin Bai, Dongsheng Pei, Junnian Zheng
Pages: 1227-1236
Published online on: 24 December 2015

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Review

The role of exosomes in tumor progression and metastasis (Review)

Wiktoria M. Suchorska, Michal S. Lach
Pages: 1237-1244
Published online on: 22 December 2015

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Review

Targeted therapy for gastric cancer: Current status and future directions (Review)

Dan-Dan Yuan, Zhong-Xiu Zhu, Xia Zhang, Jie Liu
Pages: 1245-1254
Published online on: 29 December 2015

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Article Open Access

Selenite-induced autophagy antagonizes apoptosis in colorectal cancer cells in vitro and in vivo

Yang Yang, Hui Luo, Kaiyuan Hui, Yali Ci, Kejian Shi, Ge Chen, Lei Shi, Caimin Xu
Pages: 1255-1264
Published online on: 10 December 2015

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Article Open Access

Ocoxin® oral solution slows down tumor growth in an experimental model of colorectal cancer metastasis to the liver in Balb/c mice

Joana Márquez, Jorge Mena, Iera Hernandez-Unzueta, Aitor Benedicto, Eduardo Sanz, Beatriz Arteta, Elvira Olaso
Pages: 1265-1272
Published online on: 16 December 2015

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Article Open Access

FAM172A modulates apoptosis and proliferation of colon cancer cells via STAT1 binding to its promoter Retraction in /10.3892/or.2023.8545

Kai Qian, Jinqian Zhang, Jingbo Lu, Wenjun Liu, Xingxing Yao, Qing Chen, Shun Lu, Guoan Xiang, Hao Liu
Pages: 1273-1280
Published online on: 10 December 2015

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Article Open Access

Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients

Khayal Al-Khayal, Maha Abdulla, Omar Al-Obeed, Wael Al Kattan, Ahmad Zubaidi, Mansoor-Ali Vaali-Mohammed, Abdulmalik Alsheikh, Rehan Ahmad
Pages: 1281-1286
Published online on: 17 December 2015

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Article Open Access

3-Bromopyruvate and sodium citrate target glycolysis, suppress survivin, and induce mitochondrial-mediated apoptosis in gastric cancer cells and inhibit gastric orthotopic transplantation tumor growth

Ting-An Wang, Xiao-Dong Zhang, Xing-Yu Guo, Shu-Lin Xian, Yun-Fei Lu
Pages: 1287-1296
Published online on: 23 December 2015

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Article Open Access

Local recurrence of small cell lung cancer following radiofrequency ablation is induced by HIF‑1α expression in the transition zone

Jun Wan, Wei Wu, Renquan Zhang
Pages: 1297-1308
Published online on: 31 December 2015

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Article Open Access

Clinical significance of tumor expression of major histocompatibility complex class I-related chains A and B (MICA/B) in gastric cancer patients

Carolina Hager Ribeiro, Karina Kramm, Felipe Gálvez-Jirón, Víctor Pola, Marco Bustamante, Hector R. Contreras, Andrea Sabag, Macarena Garrido-Tapia, Carolina J. Hernández, Roberto Zúñiga, Norberto Collazo, Pablo Hernán Sotelo, Camila Morales, Luis Mercado, Diego Catalán, Juan Carlos Aguillón, María Carmen Molina
Pages: 1309-1317
Published online on: 23 December 2015

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Article Open Access

Sulfatase 2 promotes breast cancer progression through regulating some tumor-related factors

Chenfang Zhu, Liu He, Xin Zhou, Xin Nie, Yan Gu
Pages: 1318-1328
Published online on: 28 December 2015

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Article Open Access

A matrix metalloproteinase inhibitor enhances anti-cytotoxic T lymphocyte antigen-4 antibody immunotherapy in breast cancer by reprogramming the tumor microenvironment

Mingyue Li, Shugang Xing, Haiying Zhang, Siqi Shang, Xiangxiang Li, Bo Ren, Gaiyun Li, Xiaona Chang, Yilei Li, Wei Li
Pages: 1329-1339
Published online on: 05 January 2016

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Article

Exenatide inhibits the growth of endometrial cancer Ishikawa xenografts in nude mice

Yu Zhang, Fen Xu, Hua Liang, Mengyin Cai, Xinqiao Wen, Xiaomao Li, Jianping Weng
Pages: 1340-1348
Published online on: 08 December 2015

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Article

Expression of DNA double-strand break repair proteins predicts the response and prognosis of colorectal cancer patients undergoing oxaliplatin-based chemotherapy

Keisuke Ihara, Satoru Yamaguchi, Nozomi Ueno, Yukiko Tani, Yosuke Shida, Hideo Ogata, Yasushi Domeki, Kentaro Okamoto, Masanobu Nakajima, Kinro Sasaki, Takashi Tsuchioka, Hiroyuki Mitomi, Hiroyuki Kato
Pages: 1349-1355
Published online on: 16 December 2015

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Article

Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR-30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Pages: 1356-1364
Published online on: 22 December 2015

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Article

miR-203 promotes proliferation, migration and invasion by degrading SIK1 in pancreatic cancer

Zhi-Guo Ren, Shu-Xiao Dong, Ping Han, Jian Qi
Pages: 1365-1374
Published online on: 29 December 2015

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Article

5-Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene

Xiaorong Wang, E. Chen, Xue Yang, Yin Wang, Zhen Quan, Xiaohou Wu, Chunli Luo
Pages: 1375-1384
Published online on: 17 December 2015

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Article

MicroRNA-124-3p inhibits the growth and metastasis of nasopharyngeal carcinoma cells by targeting STAT3 Retraction in /10.3892/or.2024.8807

Shan Xu, Ning Zhao, Lian Hui, Min Song, Zi-Wei Miao, Xue-Jun Jiang
Pages: 1385-1394
Published online on: 28 December 2015

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Article

SIRT6 suppresses glioma cell growth via induction of apoptosis, inhibition of oxidative stress and suppression of JAK2/STAT3 signaling pathway activation

Jun Feng, Peng‑Fei Yan, Hong‑Yang Zhao, Fang‑Cheng Zhang, Wo‑Hua Zhao, Min Feng
Pages: 1395-1402
Published online on: 08 December 2015

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Article

Expression and mechanism of microRNA-181A on incidence and survival in late liver metastases of colorectal cancer

Zengjun Li, Haipeng Wang, Zhongfa Xu, Yanlai Sun, Jianjun Han
Pages: 1403-1408
Published online on: 05 January 2016

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Article

Marginal zinc intake reduces the protective effect of lactation on mammary gland carcinogenesis in a DMBA-induced tumor model in mice

Zeynep Bostanci, Ronald P. Mack, Laura M. Enomoto, Samina Alam, Ashley Brown, Carola Neumann, David I. Soybel, Shannon L. Kelleher
Pages: 1409-1416
Published online on: 22 December 2015

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Article

Selective and augmented β-glucuronidase expression combined with DOX-GA3 application elicits the potent suppression of prostate cancer

Longxin Wang, Jie Dong, Ming Wei, Weihong Wen, Jianping Gao, Zhengyu Zhang, Weijun Qin
Pages: 1417-1424
Published online on: 26 November 2015

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Article

MicroRNA-148a inhibits breast cancer migration and invasion by directly targeting WNT-1 Corrigendum in /10.3892/or.2022.8317

Qian Jiang, Miao He, Meng-Tao Ma, Hui-Zhe Wu, Zhao-Jin Yu, Shu Guan, Long-Yang Jiang, Yan Wang, Da-Di Zheng, Feng Jin, Min-Jie Wei
Pages: 1425-1432
Published online on: 21 December 2015

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Article

Tyrosine kinase inhibitors target cancer stem cells in renal cell cancer

Anna M. Czarnecka, Wojciech Solarek, Anna Kornakiewicz, Cezary Szczylik
Pages: 1433-1442
Published online on: 24 December 2015

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Article

Hepatitis B virus induces hypoxia-inducible factor-2α expression through hepatitis B virus X protein

Jian‑Li Hu, Li‑Ping Liu, Sheng‑Li Yang, Xiefan Fang, Lu Wen, Quan‑Guang Ren, Chao Yu
Pages: 1443-1448
Published online on: 08 December 2015

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Article

Diagnostic and predictive significance of serum microRNA-7 in esophageal squamous cell carcinoma

Wei Dong, Baosheng Li, Juan Wang, Yipeng Song, Zicheng Zhang, Chengrui Fu, Peiliang Zhang
Pages: 1449-1456
Published online on: 21 December 2015

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Article

Intrinsic effects of gold nanoparticles on proliferation and invasion activity in SGC-7901 cells

Yucheng Wu, Qingqing Zhang, Zhongbao Ruan, Yigang Yin
Pages: 1457-1462
Published online on: 08 December 2015

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Article

Theracurmin® efficiently inhibits the growth of human prostate and bladder cancer cells via induction of apoptotic cell death and cell cycle arrest

Minyong Kang, Jin-Nyoung Ho, Ha Rim Kook, Sangchul Lee, Jong Jin Oh, Sung Kyu Hong, Sang Eun Lee, Seok-Soo Byun
Pages: 1463-1472
Published online on: 29 December 2015

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Article

miR-17-5p promotes the growth of osteosarcoma in a BRCC2-dependent mechanism Retraction in /10.3892/or.2024.8710

Wei Wang, Liang Zhang, Ke Zheng, Xiaojing Zhang
Pages: 1473-1482
Published online on: 05 January 2016

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Article

IGFBP7 functions as a potential lymphangiogenesis inducer in non-small cell lung carcinoma

Weipeng Zhao, Jun Wang, Bo Zhu, Yuzhong Duan, Fanglin Chen, Weiqi Nian, Jianguo Sun, Bicheng Zhang, Zhongsheng Tong, Zhengtang Chen
Pages: 1483-1492
Published online on: 24 December 2015

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Article

Expression and regulation of COP1 in chronic lymphocytic leukemia cells for promotion of cell proliferation and tumorigenicity

Chunling Fu, Yanqing Gong, Xuanxuan Shi, Hengliang Shi, Yan Wan, Qingyun Wu, Kailin Xu
Pages: 1493-1500
Published online on: 28 December 2015

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Article

Cinnamaldehyde affects the biological behavior of human colorectal cancer cells and induces apoptosis via inhibition of the PI3K/Akt signaling pathway

Jiepin Li, Yuhao Teng, Shenlin Liu, Zifan Wang, Yan Chen, Yingying Zhang, Songyang Xi, Song Xu, Ruiping Wang, Xi Zou
Pages: 1501-1510
Published online on: 17 December 2015

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Article

Loss of imprinting of IGF2 in fibroadenomas and phyllodes tumors of the breast

Chieko Mishima, Naofumi Kagara, Tomonori Tanei, Yasuto Naoi, Masafumi Shimoda, Atsushi Shimomura, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
Pages: 1511-1518
Published online on: 16 December 2015

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Article

Genetic analysis in a patient with nine primary malignant neoplasms: a rare case of Li-Fraumeni syndrome

Xiaoyuan Li, Juan Kang, Qi Pan, Weronika Sikora-Wohlfeld, Dachun Zhao, Changting Meng, Chunmei Bai, Anil Patwardhan, Richard Chen, Hong Ren, Atul J. Butte, Keyue Ding
Pages: 1519-1528
Published online on: 21 December 2015

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Article

Differential expression profiles of long non-coding RNAs reveal potential biomarkers for identification of human gastric cancer

Chengyun Li, Geyu Liang, Wenzhuo Yao, Jing Sui, Xian Shen, Yanqiu Zhang, Shumei Ma, Yancheng Ye, Zhiyi Zhang, Wenhua Zhang, Lihong Yin, Yuepu Pu
Pages: 1529-1540
Published online on: 29 December 2015

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Article

Downregulation of human intercellular adhesion molecule-1 attenuates the metastatic ability in human breast cancer cell lines

Dalin Di, Lei Chen, Lina Wang, Ping Sun, Yanfei Liu, Zhiwei Xu, Jiyu Ju
Pages: 1541-1548
Published online on: 05 January 2016

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Article

HIF-1α/MDR1 pathway confers chemoresistance to cisplatin in bladder cancer

Yi Sun, Zhenfeng Guan, Liang Liang, Yongyi Cheng, Jiancheng Zhou, Jing Li, Yonggang Xu
Pages: 1549-1556
Published online on: 29 December 2015

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Article

CXCL16 induces angiogenesis in autocrine signaling pathway involving hypoxia-inducible factor 1α in human umbilical vein endothelial cells

Xiaowen Yu, Renping Zhao, Sensen Lin, Xianshu Bai, Luyong Zhang, Shengtao Yuan, Li Sun
Pages: 1557-1565
Published online on: 24 December 2015

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Article

AMPK interacts with β-catenin in the regulation of hepatocellular carcinoma cell proliferation and survival with selenium treatment

Song Yi Park, Yun-Kyoung Lee, Hyun Jung Kim, Ock Jin Park, Young Min Kim
Pages: 1566-1572
Published online on: 24 December 2015

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Article

Vesicular stomatitis virus is a potent agent for the treatment of malignant ascites

Yi Zhou, Feng Wen, Pengfei Zhang, Ruilei Tang, Qiu Li
Pages: 1573-1581
Published online on: 24 December 2015

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Article

The anti-diabetic drug metformin inhibits pancreatic cancer cell proliferation in vitro and in vivo: Study of the microRNAs associated with the antitumor effect of metformin

Kiyohito Kato, Hisakazu Iwama, Takuma Yamashita, Kiyoyuki Kobayashi, Shintaro Fujihara, Takayuki Fujimori, Hideki Kamada, Hideki Kobara, Tsutomu Masaki
Pages: 1582-1592
Published online on: 17 December 2015

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Article

CD24 promotes the proliferation and inhibits the apoptosis of cervical cancer cells in vitro

Zhen Pei, Guangchao Zhu, Xiaolei Huo, Lu Gao, Shan Liao, Junyu He, Yuehua Long, Hong Yi, Songshu Xiao, Wei Yi, Pan Chen, Xiaoling Li, Guiyuan Li, Yanhong Zhou
Pages: 1593-1601
Published online on: 24 December 2015

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Article

Quercetin inhibits angiogenesis through thrombospondin-1 upregulation to antagonize human prostate cancer PC-3 cell growth in vitro and in vivo

Feiya Yang, Xian Jiang, Liming Song, Huiping Wang, Zhu Mei, Zhiqing Xu, Nianzeng Xing
Pages: 1602-1610
Published online on: 09 December 2015

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Article

Analysis of novel microRNA targets in drug-sensitive and -insensitive small cell lung cancer cell lines

Lijie Ma, Peipei Li, Ruixuan Wang, Yandong Nan, Xueying Liu, Faguang Jin
Pages: 1611-1621
Published online on: 16 December 2015

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Article

Liver epithelial cells inhibit proliferation and invasiveness of hepatoma cells

Kuo-Shyang Jeng, Chi-Juei Jeng, Wen-Juei Jeng, I-Shyan Sheen, Shih-Yun Li, Zih-Hang Hung, Hsin-I Hsiau, Ming-Che Yu, Chiung-Fang Chang
Pages: 1622-1628
Published online on: 08 December 2015

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Article

Autophagy-associated proteins BAG3 and p62 in testicular cancer

Georg Bartsch, Lukas Jennewein, Patrick N. Harter, Patrick Antonietti, Roman A. Blaheta, Hans-Michael Kvasnicka, Donat Kögel, Axel Haferkamp, Michel Mittelbronn, Jens Mani
Pages: 1629-1635
Published online on: 22 December 2015

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Article

Redox cycling of a copper complex with benzaldehyde nitrogen mustard-2-pyridine carboxylic acid hydrazone contributes to its enhanced antitumor activity, but no change in the mechanism of action occurs after chelation

Yinli Yang, Cuiping Li, Yun Fu, Youxun Liu, Yu Zhang, Yanfang Zhang, Pingxin Zhou, Yanbin Yuan, Sufeng Zhou, Shaoshan Li, Changzheng Li
Pages: 1636-1644
Published online on: 29 December 2015

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Article

miR-27b is upregulated in cervical carcinogenesis and promotes cell growth and invasion by regulating CDH11 and epithelial-mesenchymal transition

Jihang Yao, Boya Deng, Le Zheng, Lei Dou, Yi Guo, Kejun Guo
Pages: 1645-1651
Published online on: 21 December 2015

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Article

A novel method for endothelial cell isolation

Qiqi Mao, Xianing Huang, Jian He, Wei Liang, Yi Peng, Jing Su, Yingying Huang, Zixi Hu, Xiaoling Lu, Yongxiang Zhao
Pages: 1652-1656
Published online on: 16 December 2015

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Article

TALEN-induced disruption of Nanog expression results in reduced proliferation, invasiveness and migration, increased chemosensitivity and reversal of EMT in HepG2 cells

Ai Qing Yu, Yan Ding, Cheng Lin Li, Yi Yang, Shi Rong Yan, Dong Sheng Li
Pages: 1657-1663
Published online on: 10 December 2015

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Article

REV3L, the catalytic subunit of DNA polymerase ζ, is involved in the progression and chemoresistance of esophageal squamous cell carcinoma

Xiaozhong Zhu, Shitao Zou, Jundong Zhou, Hongsheng Zhu, Shuyu Zhang, Zengfu Shang, Wei-Qun Ding, Jinchang Wu, Yihong Chen
Pages: 1664-1670
Published online on: 05 January 2016

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Article

Tumor suppressor role of miR-217 in human epithelial ovarian cancer by targeting IGF1R Retraction in /10.3892/or.2022.8415

Jieyan Li, Dongmei Li, Weiyuan Zhang
Pages: 1671-1679
Published online on: 18 December 2015

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Article

Dual inhibition of COX-2/5-LOX blocks colon cancer proliferation, migration and invasion in vitro Retraction in /10.3892/or.2024.8845

Xiao-Hang Che, Chun-Lin Chen, Xiao-Lei Ye, Guo-Bin Weng, Xian-Zhi Guo, Wen-Ying Yu, Jin Tao, Yi-Chen Chen, Xiaodong Chen
Pages: 1680-1688
Published online on: 22 December 2015

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Article

Overexpressed genes associated with hormones in terminal ductal lobular units identified by global transcriptome analysis: An insight into the anatomic origin of breast cancer

Jianmin Yang, Haijing Yu, Liang Zhang, Hua Deng, Qi Wang, Wenping Li, Anqin Zhang, Hongyi Gao, Aihua Yin
Pages: 1689-1695
Published online on: 28 December 2015

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Article

miR-497 suppresses angiogenesis in breast carcinoma by targeting HIF-1α

Zhihao Wu, Xuehong Cai, Chenggang Huang, Jia Xu, An Liu
Pages: 1696-1702
Published online on: 29 December 2015

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Article

Protein N-arginine methyltransferase 5 promotes the tumor progression and radioresistance of nasopharyngeal carcinoma

Daoke Yang, Tiansong Liang, Yue Gu, Yulin Zhao, Yonggang Shi, Xiaoxiao Zuo, Qinchen Cao, Ya Yang, Quancheng Kan
Pages: 1703-1710
Published online on: 24 December 2015

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Article

Antitumor activity of rhein lysinate against human glioma U87 cells in vitro and in vivo

Jin Liu, Ke Zhang, Yong-Zhan Zhen, Jie Wei, Gang Hu, Jun-Ling Gao, Yan-Xia Tian, Ya-Jun Lin
Pages: 1711-1717
Published online on: 24 December 2015

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Article

Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway

Wei Li, Lei Cao, Xin Chen, Jianjun Lei, Qingyong Ma
Pages: 1718-1726
Published online on: 22 December 2015

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Article

Low skeletal muscle density is associated with poor survival in patients who receive chemotherapy for metastatic gastric cancer

Naomi Hayashi, Yuichi Ando, Bishal Gyawali, Tomoya Shimokata, Osamu Maeda, Masahide Fukaya, Hidemi Goto, Masato Nagino, Yasuhiro Kodera
Pages: 1727-1731
Published online on: 08 December 2015

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Article

Consecutive salinomycin treatment reduces doxorubicin resistance of breast tumor cells by diminishing drug efflux pump expression and activity

Adam Hermawan, Ernst Wagner, Andreas Roidl
Pages: 1732-1740
Published online on: 22 December 2015

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Article

The oncolytic herpes simplex virus vector, G47Δ, effectively targets tamoxifen-resistant breast cancer cells

Jingjing Fan, Hua Jiang, Lin Cheng, Renbin Liu
Pages: 1741-1749
Published online on: 30 December 2015

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Article

Effects of CD73 on human colorectal cancer cell growth in vivo and in vitro

Ruimin Wu, Yijia Chen, Fuyan Li, Wei Li, Hong Zhou, Yi Yang, Zhijun Pei
Pages: 1750-1756
Published online on: 23 December 2015

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Article

MicroRNA-30a downregulation contributes to chemoresistance of osteosarcoma cells through activating Beclin-1-mediated autophagy

Ruida Xu, Shuzhong Liu, Haihong Chen, Lifeng Lao
Pages: 1757-1763
Published online on: 18 December 2015

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Article

CD151 knockdown inhibits osteosarcoma metastasis through the GSK-3β/β-catenin/MMP9 pathway

Zhiyu Zhang, Feng Wang, Qin Li, Haifei Zhang, Yan Cui, Chengbin Ma, Jiajun Zhu, Xueyuan Gu, Zhenguo Sun
Pages: 1764-1770
Published online on: 24 December 2015

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Article

MicroRNA-Let-7f reduces the vasculogenic mimicry of human glioma cells by regulating periostin-dependent migration

Hao Xue, Xiao Gao, Shugang Xu, Jinsen Zhang, Xing Guo, Shaofeng Yan, Tong Li, Xiaofan Guo, Qinglin Liu, Gang Li
Pages: 1771-1777
Published online on: 05 January 2016

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Article

Downregulation of microRNA-206 suppresses clear cell renal carcinoma proliferation and invasion by targeting vascular endothelial growth factor A Retraction in /10.3892/or.2024.8717

Yi Cai, Hanzhong Li, Yushi Zhang
Pages: 1778-1786
Published online on: 30 December 2015

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Article

IL-6 mediates the signal pathway of JAK-STAT3-VEGF-C promoting growth, invasion and lymphangiogenesis in gastric cancer

Guibin Zhao, Guangwei Zhu, Yongjian Huang, Wei Zheng, Jin Hua, Shugang Yang, Jinfu Zhuang, Jianxin Ye
Pages: 1787-1795
Published online on: 05 January 2016

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Article

SALL4 is a marker of poor prognosis in serous ovarian carcinoma promoting invasion and metastasis

Mengyuan Yang, Xiaohui Xie, Yiling Ding
Pages: 1796-1806
Published online on: 05 January 2016

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Article

Smad4 sensitizes colorectal cancer to 5-fluorouracil through cell cycle arrest by inhibiting the PI3K/Akt/CDC2/survivin cascade

Binhao Zhang, Chao Leng, Chao Wu, Zhanguo Zhang, Lei Dou, Xin Luo, Bixiang Zhang, Xiaoping Chen
Pages: 1807-1815
Published online on: 08 December 2015

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Article

miR-215 functions as a tumor suppressor in epithelial ovarian cancer through regulation of the X-chromosome-linked inhibitor of apoptosis

Guanqun Ge, Wei Zhang, Ligang Niu, Yu Yan, Yu Ren, Yuliang Zou
Pages: 1816-1822
Published online on: 09 December 2015

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Article

BMP-6 inhibits the metastasis of MDA-MB-231 breast cancer cells by regulating MMP-1 expression Corrigendum in /10.3892/or.2024.8822

Fen Hu, Yunfeng Zhang, Mi Li, Lina Zhao, Jing Chen, Shuang Yang, Xiujun Zhang
Pages: 1823-1830
Published online on: 31 December 2015

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Article

MicroRNA-381 suppresses cell growth and invasion by targeting the liver receptor homolog-1 in hepatocellular carcinoma

Qianqian Zhang, Shixing Zhao, Xiaoli Pang, Baorong Chi
Pages: 1831-1840
Published online on: 16 December 2015

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Article

Sosiho‑tang ameliorates cachexia‑related symptoms in mice bearing colon 26 adenocarcinoma by reducing systemic inflammation and muscle loss

Aeyung Kim, Minju Im, Jin Yeul Ma
Pages: 1841-1850
Published online on: 28 December 2015

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Article

MicroRNA-154 functions as a tumor suppressor in osteosarcoma by targeting Wnt5a Retraction in /10.3892/or.2021.8130

Hui Zhou, Minglei Zhang, Hongping Yuan, Wei Zheng, Chunyan Meng, Dongxu Zhao
Pages: 1851-1858
Published online on: 17 December 2015

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Article

Complex analysis of the p53 tumor suppressor in lung carcinoma

Jana Smardova, Kvetoslava Liskova, Barbora Ravcukova, Jitka Malcikova, Jitka Hausnerova, Miluse Svitakova, Renata Hrabalkova, Lenka Zlamalikova, Katerina Stano-Kozubik, Ivona Blahakova, Jana Speldova, Jiri Jarkovsky, Jan Smarda
Pages: 1859-1867
Published online on: 29 December 2015

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Article

All-trans retinoic acid enhances bystander effect of suicide gene therapy in the treatment of breast cancer

Heng Kong, Xia Liu, Liucheng Yang, Ke Qi, Haoyun Zhang, Jingwen Zhang, Zonghai Huang, Hongxian Wang
Pages: 1868-1874
Published online on: 29 December 2015

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Article

Cell adhesion downregulates the expression of Homer1b/c and contributes to drug resistance in multiple myeloma cells

Jie Tang, Hongxuan Zhou, Chun Wang, Xiaodong Fei, Liqun Zhu, Yuejiao Huang, Yunhua He, Jing Liu, Xiaobing Miao, Yaxun Wu, Yuchan Wang
Pages: 1875-1883
Published online on: 29 December 2015

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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