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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2012 Volume 30 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Evolving applications of microarray technology in postnatal diagnosis (Review)

Ji Un Kang, Sun Hoe Koo
Pages: 223-228
Published online on: 09 May 2012

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Article Open Access

Proteomics reveals drastic increase of extracellular matrix proteins collagen and dermatopontin in the aged mdx diaphragm model of Duchenne muscular dystrophy

Steven Carberry, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck
Pages: 229-234
Published online on: 18 May 2012

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Article

Expression of muscle-specific integrins in masseter muscle fibers during malocclusion disease

Giuseppina Cutroneo, Maria Grazia Piancino, Guglielmo Ramieri, Pietro Bracco, Giuseppe Vita, Gaetano Isola, Giovanna Vermiglio, Angelo Favaloro, Giuseppe Anastasi, Fabio Trimarchi
Pages: 235-242
Published online on: 30 April 2012

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Article

Gibberellic acid induces α-amylase expression in adipose-derived stem cells

Atsushi Kasamatsu, Manabu Iyoda, Katsuya Usukura, Yosuke Sakamoto, Katsunori Ogawara, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa
Pages: 243-247
Published online on: 22 May 2012

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Article

Oral administration of Enterococcus faecalis FK-23 suppresses Th17 cell development and attenuates allergic airway responses in mice

Bei Zhang, Jun An, Takashi Shimada, Shuang Liu, Kazutaka Maeyama
Pages: 248-254
Published online on: 24 May 2012

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Article

NFKB1 polymorphism is associated with age-related gene methylation in Helicobacter pylori-infected subjects

Tomiyasu Arisawa, Tomomitsu Tahara, Hisakazu Shiroeda, Hideto Yamada, Tomoe Nomura, Ranji Hayashi, Takashi Saito, Tomoki Fukuyama, Toshimi Otsuka, Masakatsu Nakamura, Nobuyuki Toshikuni, Mutsumi Tsuchishima, Tomoyuki Shibata
Pages: 255-262
Published online on: 18 May 2012

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Article

Picroside II protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by activating the PI3K/Akt and CREB pathways

Fan-Ji Meng, Su-Min Jiao, Bo Yu
Pages: 263-270
Published online on: 09 May 2012

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Article

Impact of single-dose application of TGF-β, copper peptide, stanozolol and ascorbic acid in hydrogel on midline laparatomy wound healing in a diabetic mouse model

Moritz A. Konerding, Thomas Ziebart, Tanja Wolloscheck, Axel Wellmann, Maximilian Ackermann
Pages: 271-276
Published online on: 18 May 2012

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Article

Endogenous glucocorticoids promote the expansion of myeloid-derived suppressor cells in a murine model of trauma

Kun Zhang, Xiangjun Bai, Renjie Li, Zhengzheng Xiao, Jiajun Chen, Fan Yang, Zhanfei Li
Pages: 277-282
Published online on: 29 May 2012

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Article

Bone marrow-derived cells contribute to cell turnover in aging murine hearts

Sebastian Szardien, Holger M. Nef, Christian Troidl, Matthias Willmer, Sandra Voss, Christoph Liebetrau, Jedrzej Hoffmann, Andreas Rolf, Johannes Rixe, Albrecht Elsässer, Christian W. Hamm, Helge Möllmann
Pages: 283-287
Published online on: 09 May 2012

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Article

Serine protease inhibitor A3 in atherosclerosis and aneurysm disease

Dick Wågsäter, Daniel Johansson, Vincent Fontaine, Emina Vorkapic, Alexandra Bäcklund, Anton Razuvaev, Mikko I. Mäyränpää , Charlotta Hjerpe, Kenneth Caidahl, Anders Hamsten, Anders Franco-Cereceda, Johannes Wilbertz, Jesper Swedenborg, Xinghua Zhou, Per Eriksson
Pages: 288-294
Published online on: 09 May 2012

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Article

DMP1 is a target of let-7 in dental pulp cells

Jing Yue, Buling Wu, Jie Gao, Xin Huang, Changxia Li, Dandan Ma, Fuchun Fang
Pages: 295-301
Published online on: 25 April 2012

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Article

Cyclosporine A inhibits breast cancer cell growth by downregulating the expression of pyruvate kinase subtype M2

Kai Jiang, Baoming He, Lihua Lai, Qingyun Chen, Yang Liu, Qingming Guo, Qingqing Wang
Pages: 302-308
Published online on: 09 May 2012

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Article

Simulated microgravity decreases apoptosis in fetal fibroblasts

Michaël Beck, Kevin Tabury, Marjan Moreels, Paul Jacquet, Patrick Van Oostveldt, Winnok H. De Vos, Sarah Baatout
Pages: 309-313
Published online on: 14 May 2012

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Article

PI3K/Akt signaling pathway-induced heme oxygenase-1 upregulation mediates the adaptive cytoprotection of hydrogen peroxide preconditioning against oxidative injury in PC12 cells Expression of Concern in /10.3892/ijmm.2025.5609

Liqiu Mo, Chuntao Yang, Mofa Gu, Dongdan Zheng, Lin Lin, Xiuyu Wang, Aiping Lan, Fen Hu, Jianqiang Feng
Pages: 314-320
Published online on: 14 May 2012

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Article

Establishment of a canine model of human type 2 diabetes mellitus by overexpressing phosphoenolypyruvate carboxykinase

Yeon Woo Jeong, Geun-Shik Lee, Joung Joo Kim, Sun Woo Park, Kyeong Hee Ko, Mina Kang, Yu Kyung Kim, Eui-Man Jung, Sang Hwan Hyun, Taeyoung Shin, Eui-Bae Jeung, Woo Suk Hwang
Pages: 321-329
Published online on: 09 May 2012

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Article

Protective effects of atorvastatin against oxidized LDL-induced downregulation of KLF expression in EA.hy926 cells

Yan Gao, Xian-Feng Liu, Xue-Chun Lu, Cong Ma, Jian Cao, Li Fan
Pages: 330-336
Published online on: 14 May 2012

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Article

Genistein inhibits MDA-MB-231 triple-negative breast cancer cell growth by inhibiting NF-κB activity via the Notch-1 pathway

Hong Pan, Wenbin Zhou, Wei He, Xiaoan Liu, Qiang Ding, Lijun Ling, Xiaoming Zha, Shui Wang
Pages: 337-343
Published online on: 09 May 2012

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Article

Sparassis crispa suppresses mast cell-mediated allergic inflammation: Role of calcium, mitogen-activated protein kinase and nuclear factor-κB

Hui-Hun Kim, Soyoung Lee, Thoudam S.K. Singh, Jin Kyeong Choi, Tae-Yong Shin, Sang-Hyun Kim
Pages: 344-350
Published online on: 14 May 2012

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Article

The effects of siRNA against RPL22 on ET-1-induced proliferation of human pulmonary arterial smooth muscle cells

Kai Sun, Hong Xue, Hui Wang, Qiang Wang, Xiang-Rong Zuo, Wei-Ping Xie, Hong Wang
Pages: 351-357
Published online on: 09 May 2012

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Article

Adenovirus-mediated TRAIL expression and downregulation of Bcl-2 expression suppresses non-small cell lung cancer growth in vitro and in vivo

Haiping Zhang, Aihua Sui, Zhenli Wang, Shihai Liu, Ruyong Yao
Pages: 358-364
Published online on: 14 May 2012

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Article

Enrichment of neural-related genes in human mesenchymal stem cells from neuroblastoma patients

Miguel Ángel Rodriguez-Milla, Isabel Mirones, Luis Mariñas-Pardo, Gustavo J. Melen, Isabel Cubillo, Manuel Ramírez, Javier García-Castro
Pages: 365-373
Published online on: 22 May 2012

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Article

Differentially expressed microRNAs in Huh-7 cells expressing HCV core genotypes 3a or 1b: Potential functions and downstream pathways

Yu Gu, Yuqiao Xu, Lina Jiang, Xiangmei Cao, Fang Liu, Hang Li, Liying Zhang, Zengshan Li, Jing Li, Jing Ye, Qing Li
Pages: 374-382
Published online on: 09 May 2012

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Article

Senescence is accelerated through donor cell specificity in cloned pigs

Hyun Yong Jeon, Yeon Woo Jeong, Yeon Wook Kim, Yeon Ik Jeong, Shamim M. Hossein, Hyun Yang, Sang Hwan Hyun, Eui-Bae Jeung, Woo Suk Hwang
Pages: 383-391
Published online on: 18 May 2012

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Article

UV radiation-induced skin aging in hairless mice is effectively prevented by oral intake of sea buckthorn (Hippophae rhamnoides L.) fruit blend for 6 weeks through MMP suppression and increase of SOD activity

In Sik Hwang, Ji Eun Kim, Sun Il Choi, Hye Ryun Lee, Young Ju Lee, Min Ju Jang, Hong Ju Son, Hee Seob Lee, Chung Hun Oh, Bae Hwan Kim, Sang Hak Lee, Dae Youn Hwang
Pages: 392-400
Published online on: 24 May 2012

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Article

Interleukin gene polymorphisms in pneumoconiosis

Simone Helmig, Martin Grossmann, Jelena Wübbeling, Joachim Schneider
Pages: 401-408
Published online on: 10 May 2012

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Article

Aldose reductase regulates platelet-derived growth factor-induced proliferation through mediating cell cycle progression in rat mesangial cells

Liping Zou, Wenjuan Wang, Zude Xu, Nong Zhang, Tao Jiang
Pages: 409-416
Published online on: 14 May 2012

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Article

Proteomic analysis of calcified abdominal and thoracic aortic aneurysms

Ken-Ichi Matsumoto, Tomoko Maniwa, Tetsuya Tanaka, Kazumi Satoh, Hideki Okunishi, Teiji Oda
Pages: 417-429
Published online on: 30 April 2012

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Article

UCHL1 acts as a colorectal cancer oncogene via activation of the β-catenin/TCF pathway through its deubiquitinating activity

Jialing Zhong, Mei Zhao, Yiming Ma, Qing Luo, Jian Liu, Jia Wang, Xinghua Yuan, Jianli Sang, Changzhi Huang
Pages: 430-436
Published online on: 25 May 2012

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Article

A technique for capturing broad subtypes and circulating recombinant forms of HIV-1 based on anionic polymer-coated magnetic beads

Akikazu Sakudo, Kazuyoshi Ikuta
Pages: 437-442
Published online on: 22 May 2012

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Article

Inhibition of Bcl-xL by ABT-737 enhances chemotherapy sensitivity in neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor cells

Su-Jin Lee, Ho-Jin Park, Young-Hwa Kim, Bo-Young Kim, Hyun-Seok Jin, Hyon J. Kim, Jae-Ho Han, Hyunee Yim, Seon-Yong Jeong
Pages: 443-450
Published online on: 29 May 2012

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Article Open Access

Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Article Open Access

Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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Article Open Access

ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Review Open Access

Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Review Open Access

Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Review Open Access

Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Review Open Access

Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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Article Open Access

4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Review Open Access

Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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Review Open Access

m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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Article Open Access

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Review Open Access

Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Review Open Access

Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Review Open Access

Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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Review Open Access

CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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June-2026 Volume 57 Issue 6

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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