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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2016 Volume 38 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review)

Masaru Katoh
Pages: 3-15
Published online on: 31 May 2016

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Review

Intercellular and intracellular functions of ceramides and their metabolites in skin (Review)

Hwa Jun Cha, Congfen He, Hua Zhao, Yinmao Dong, In-Sook An, Sungkwan An
Pages: 16-22
Published online on: 20 May 2016

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Review Open Access

Advances in stem cell therapy for cardiovascular disease (Review)

Rongrong Sun, Xianchi Li, Min Liu, Yi Zeng, Shuang Chen, Peying Zhang
Pages: 23-29
Published online on: 25 May 2016

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Article Open Access

Receptor FGFRL1 does not promote cell proliferation but induces cell adhesion

Xiaochen Yang, Florian Steinberg, Lei Zhuang, Ralph Bessey, Beat Trueb
Pages: 30-38
Published online on: 23 May 2016

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Article Open Access

Identification of novel potent human testis-specific and bromodomain-containing protein (BRDT) inhibitors using crystal structure-based virtual screening

Nana Gao, Jixia Ren, Li Hou, Yue Zhou, Ling Xin, Jiedong Wang, Heming Yu, Yong Xie, Huiping Wang
Pages: 39-44
Published online on: 23 May 2016

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Article Open Access

CD5-mediated inhibition of TCR signaling proceeds normally in the absence of SHP-1

Baoxia Dong, Ally-Khan Somani, Paul E. Love, Xuan Zheng, Xiequn Chen, Jinyi Zhang
Pages: 45-56
Published online on: 17 May 2016

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Article Open Access

Magnetically induced electrostimulation of human osteoblasts results in enhanced cell viability and osteogenic differentiation

Bettina Hiemer, Josefin Ziebart, Anika Jonitz-Heincke, Philip Christian Grunert, Yukun Su, Doris Hansmann, Rainer Bader
Pages: 57-64
Published online on: 16 May 2016

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Article Open Access

Correlation of 5-HTT, BDNF and NPSR1 gene polymorphisms with anxiety and depression in asthmatic patients

Yuan Yang, Mingzhe Zhao, Yuqun Zhang, Xinhua Shen, Yonggui Yuan
Pages: 65-74
Published online on: 09 May 2016

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Article Open Access

Involvement of NADPH oxidases in alkali burn-induced corneal injury

Xue-Jun Gu, Xian Liu, Ying-Ying Chen, Yao Zhao, Man Xu, Xiao-Jian Han, Qiu-Ping Liu, Jing-Lin Yi, Jing-Ming Li
Pages: 75-82
Published online on: 17 May 2016

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Article Open Access

Synergistic cardioprotective effects of Danshensu and hydroxysafflor yellow A against myocardial ischemia-reperfusion injury are mediated through the Akt/Nrf2/HO-1 pathway Corrigendum in /10.3892/ijmm.2021.5045

Tianxin Hu, Guo Wei, Miaomiao Xi, Jiajia Yan, Xiaoxiao Wu, Yanhua Wang, Yanrong Zhu, Chao Wang, Aidong Wen
Pages: 83-94
Published online on: 11 May 2016

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Article Open Access

In vitro differentiation of endometrial regenerative cells into smooth muscle cells: Α potential approach for the management of pelvic organ prolapse

Xiuhui Chen, Xianchao Kong, Dongzhe Liu, Peng Gao, Yanhua Zhang, Peiling Li, Meimei Liu
Pages: 95-104
Published online on: 17 May 2016

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Article Open Access

GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia

Junjie Lu, Qian Zhang, Dongmei Tan, Wenping Luo, Hai Zhao, Jing Ma, Hao Liang, Yi Tan
Pages: 105-112
Published online on: 25 May 2016

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Article Open Access

miR-1 suppresses the growth of esophageal squamous cell carcinoma in vivo and in vitro through the downregulation of MET, cyclin D1 and CDK4 expression

Sen Jiang, Chao Zhao, Xiaodi Yang, Xiangyang Li, Qing Pan, Haijin Huang, Xuyang Wen, Husheng Shan, Qianwen Li, Yunxiang Du, Yaping Zhao
Pages: 113-122
Published online on: 31 May 2016

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Article Open Access

Tert-butylhydroquinone attenuates the ethanol-induced apoptosis of and activates the Nrf2 antioxidant defense pathway in H9c2 cardiomyocytes

Xiaojing Shi, Yang Li, Jun Hu, Bo Yu
Pages: 123-130
Published online on: 25 May 2016

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Article Open Access

Altered expression of miR-92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis Retraction in /10.3892/ijmm.2024.5476

Dong-Yu Liang, Yan-Qiang Hou, Li-Jun Luo, Li Ao
Pages: 131-138
Published online on: 26 May 2016

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Article Open Access

Zoledronic acid suppresses transforming growth factor-β-induced fibrogenesis by human gingival fibroblasts

Yuko Komatsu, Miho Ibi, Naoyuki Chosa, Seiko Kyakumoto, Masaharu Kamo, Toshiyuki Shibata, Yoshiki Sugiyama, Akira Ishisaki
Pages: 139-147
Published online on: 10 May 2016

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Article Open Access

Effects of IRF1 and IFN-β interaction on the M1 polarization of macrophages and its antitumor function

Changli Xie, Cuiying Liu, Bitao Wu, Yan Lin, Tingting Ma, Haiyu Xiong, Qin Wang, Ziwei Li, Chenyu Ma, Zhiguang Tu
Pages: 148-160
Published online on: 10 May 2016

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Article Open Access

Hypothermic machine perfusion increases A20 expression which protects renal cells against ischemia/reperfusion injury by suppressing inflammation, apoptosis and necroptosis

Zixuan Yang, Zibiao Zhong, Mingxia Li, Yan Xiong, Yanfeng Wang, Guizhu Peng, Qifa Ye
Pages: 161-171
Published online on: 12 May 2016

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Article Open Access

Jumonji AT-rich interactive domain 1B overexpression is associated with the development and progression of glioma Corrigendum in /10.3892/ijmm.2016.2682 Retraction in /10.3892/ijmm.2024.5425

Liping Fang, Jiuhan Zhao, Dan Wang, Liyu Zhu, Jian Wang, Kui Jiang
Pages: 172-182
Published online on: 30 May 2016

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Article Open Access

miR-223 enhances the sensitivity of non-small cell lung cancer cells to erlotinib by targeting the insulin-like growth factor-1 receptor

Feng-Yi Zhao, Jing Han, Xie-Wan Chen, Jiang Wang, Xu-Dong Wang, Jian-Guo Sun, Zheng-Tang Chen
Pages: 183-191
Published online on: 13 May 2016

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Article Open Access

Interleukin-6 and rs1800796 locus single nucleotide polymorphisms in response to hypoxia/reoxygenation in hepatocytes

Zhaowen Wang, Shaohan Wu, Jianhua Liao, Lin Zhong, Tonghai Xing, Junwei Fan, Zhihai Peng
Pages: 192-200
Published online on: 18 May 2016

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Article Open Access

MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis

Shiju Yan, Meng Wang, Jian Zhao, Hongtao Zhang, Chengpei Zhou, Lei Jin, Yinglong Zhang, Xiuchun Qiu, Baoan Ma, Qingyu Fan
Pages: 201-209
Published online on: 31 May 2016

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Article Open Access

Brazilin exerts protective effects against renal ischemia-reperfusion injury by inhibiting the NF-κB signaling pathway

Yanyan Jia, Jinyi Zhao, Meiyou Liu, Bingling Li, Ying Song, Yuwen Li, Aidong Wen, Lei Shi
Pages: 210-216
Published online on: 31 May 2016

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Article

Tat-ATOX1 inhibits streptozotocin-induced cell death in pancreatic RINm5F cells and attenuates diabetes in a mouse model

Eun Hee Ahn, Dae Won Kim, Min Jea Shin, Eun Ji Ryu, Ji In Yong, Seok Young Chung, Hyun Ju Cha, Sang Jin Kim, Yeon Joo Choi, Duk-Soo Kim, Sung-Woo Cho, Keunwook Lee, Yoon Shin Cho, Hyeok Yil Kwon, Jinseu Park, Won Sik Eum, Soo Young Choi
Pages: 217-224
Published online on: 20 May 2016

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Article

Tat-NOL3 protects against hippocampal neuronal cell death induced by oxidative stress through the regulation of apoptotic pathways

Eun Jeong Sohn, Min Jea Shin, Won Sik Eum, Dae Won Kim, Ji In Yong, Eun Ji Ryu, Jung Hwan Park, Su Bin Cho, Hyun Ju Cha, Sang Jin Kim, Hyeon Ji Yeo, Eun Ji Yeo, Yeon Joo Choi, Seung Kwon Im, Hae Young Kweon, Duk-Soo Kim, Yeon Hee Yu, Sung-Woo Cho, Meeyoung Park, Jinseu Park, Yong-Jun Cho, Soo Young Choi
Pages: 225-235
Published online on: 19 May 2016

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Article

Network analysis of genes involved in the enhancement of hyperthermia sensitivity by the knockdown of BAG3 in human oral squamous cell carcinoma cells

Tatsuya Yunoki, Yoshiaki Tabuchi, Atsushi Hayashi, Takashi Kondo
Pages: 236-242
Published online on: 31 May 2016

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Article

Dynamics of chromosomal aberrations, induction of apoptosis, BRCA2 degradation and sensitization to radiation by hyperthermia

Judith W.J. Bergs, Arlene L. Oei, Rosemarie ten Cate, Hans M. Rodermond, Lukas J. Stalpers, Gerrit W. Barendsen, Nicolaas A.P. Franken
Pages: 243-250
Published online on: 27 May 2016

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Article

Effect of Valeriana fauriei extract on the offspring of adult rats exposed to prenatal stress

Hwayoung Lee, Hansol Won, Jiyun Im, Young Ock Kim, Sanghyun Lee, Ik-Hyun Cho, Hyung-Ki Kim, Jun-Tack Kwon, Hak-Jae Kim
Pages: 251-258
Published online on: 16 May 2016

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Article

Roles of ZIC family genes in human gastric cancer

Gang Ma, Weijie Dai, Aiyu Sang, Xiaozhong Yang, Qianjun Li
Pages: 259-266
Published online on: 12 May 2016

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Article

RbAp48, a novel inhibitory factor that regulates the transcription of human immunodeficiency virus type 1

Juan Wang, Jin Yang, Zongxing Yang, Xiangyun Lu, Changzhong Jin, Linfang Cheng, Nanping Wu
Pages: 267-274
Published online on: 19 May 2016

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Article

Protective role of magnesium isoglycyrrhizinate in non-alcoholic fatty liver disease and the associated molecular mechanisms

Qian Xu, Ji Wang, Feifei Chen, Kaisu Lin, Mingao Zhu, Lei Chen, Xiumin Zhou, Chong Li, Hong Zhu
Pages: 275-282
Published online on: 24 May 2016

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Article

Upregulation of microRNA-450 inhibits the progression of lung cancer in vitro and in vivo by targeting interferon regulatory factor 2

Fabing Liu, Xiaobo Yu, Haihua Huang, Xi Chen, Jin Wang, Xiaomiao Zhang, Qiang Lin
Pages: 283-290
Published online on: 27 May 2016

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Article

Cedrol induces autophagy and apoptotic cell death in A549 non-small cell lung carcinoma cells through the P13K/Akt signaling pathway, the loss of mitochondrial transmembrane potential and the generation of ROS

Shi-Yi Zhang, Xue-Bo Li, Sheng-Guang Hou, Yao Sun, Yi-Ran Shi, Song-Sen Lin
Pages: 291-299
Published online on: 11 May 2016

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Article

Functional analysis of HBO1 in tumor development and inhibitor screening

Ling-Li Guo, Su-Yang Yu, Meng Li
Pages: 300-304
Published online on: 31 May 2016

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Article

Proliferative effects of gamma-amino butyric acid on oral squamous cell carcinoma cells are associated with mitogen-activated protein kinase signaling pathways

Jing Ma, Yan Zhang, Jun Wang, Tianyu Zhao, Ping Ji, Jinlin Song, Hongmei Zhang, Wenping Luo
Pages: 305-311
Published online on: 19 May 2016

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Article

MicroRNA-205‑5b inhibits HMGB1 expression in LPS-induced sepsis

Wenhai Zhou, Jing Wang, Zhifeng Li, Jianguo Li, Ming Sang
Pages: 312-318
Published online on: 27 May 2016

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Article

IL-1α induces apoptosis and inhibits the osteoblast differentiation of MC3T3-E1 cells through the JNK and p38 MAPK pathways

Chun Guo, Xu-Guang Yang, Fei Wang, Xu-Yuan Ma
Pages: 319-327
Published online on: 25 May 2016

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Article

Epigallocatechin gallate exerts protective effects against myocardial ischemia/reperfusion injury through the PI3K/Akt pathway-mediated inhibition of apoptosis and the restoration of the autophagic flux

Feifei Xuan, Jie Jian
Pages: 328-336
Published online on: 31 May 2016

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Article

Icariin alters the expression of glucocorticoid receptor, FKBP5 and SGK1 in rat brains following exposure to chronic mild stress

Kai Wei, Yizhe Xu, Zhengxiao Zhao, Xiao Wu, Yijie Du, Jing Sun, Tao Yi, Jingcheng Dong, Baojun Liu
Pages: 337-344
Published online on: 17 May 2016

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Article

Association of miR-34a, miR-130a, miR-150 and miR-155 polymorphisms with the risk of ischemic stroke

Gun Ho Choi, Ki Han Ko, Jung Oh Kim, Jinkwon Kim, Seung Hun Oh, In Bo Han, Kyung Gi Cho, Ok Joon Kim, Jinkun Bae, Nam Keun Kim
Pages: 345-356
Published online on: 25 May 2016

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Article

Biological effects of rutin on skin aging

Seong Jin Choi, Sung-Nae Lee, Karam Kim, Da Hye Joo, Shanghun Shin, Jeongju Lee, Hyun Kyung Lee, Jihyun Kim, Seung Bin Kwon, Min Jung Kim, Kyu Joong Ahn, In-Sook An, Sungkwan An, Hwa Jun Cha
Pages: 357-363
Published online on: 24 May 2016

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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Article Open Access

METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Review Open Access

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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