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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2013 Volume 29 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

New candidate therapeutic agents for endometrial cancer: Potential for clinical practice (Review)

Kiyoko Umene, Kouji Banno, Iori Kisu, Megumi Yanokura, Yuya Nogami, Kosuke Tsuji, Kenta Masuda, Arisa Ueki, Yusuke Kobayashi, Wataru Yamagami, Eiichiro Tominaga, Nobuyuki Susumu, Daisuke Aoki
Pages: 855-860
Published online on: 03 January 2013

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Review

Pathogenesis and malignant transformation of adenomyosis (Review)

Natsuki Koike, Taihei Tsunemi, Chiharu Uekuri, Juria Akasaka, Fuminori Ito, Aiko Shigemitsu, Hiroshi Kobayashi
Pages: 861-867
Published online on: 13 December 2012

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Article Open Access

Effects of the activated mitogen-activated protein kinase pathway via the c-ros receptor tyrosine kinase on the T47D breast cancer cell line following alcohol exposure

Hyung Tae Lee, Se Kye Kim, Mi Ran Choi, Ji Hyun Park, Kyoung Hwa Jung, Young Gyu Chai
Pages: 868-874
Published online on: 24 December 2012

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Article Open Access

Oxidative stress-induced 1, N6-ethenodeoxyadenosine adduct formation contributes to hepatocarcinogenesis

Lei Zhou, Yuzhen Yang, Dean Tian, Ying Wang
Pages: 875-884
Published online on: 04 January 2013

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Article Open Access

Retinoic acid inhibits the cytoproliferative response to weak 50‑Hz magnetic fields in neuroblastoma cells

María Ángeles Trillo, María Antonia Martínez, María Antonia Cid, Alejandro Úbeda
Pages: 885-894
Published online on: 24 December 2012

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Article Open Access

The combination of an oxygen-dependent degradation domain-regulated adenovirus expressing the chemokine RANTES/CCL5 and NK-92 cells exerts enhanced antitumor activity in hepatocellular carcinoma

Jiang Li, Hui Liu, Linfang Li, Hongping Wu, Chunhong Wang, Zi Yan, Ying Wang, Changqing Su, Huajun Jin, Fuping Zhou, Mengchao Wu, Qijun Qian
Pages: 895-902
Published online on: 28 December 2012

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Article Open Access

Cyclin-dependent kinase-associated protein phosphatase is overexpressed in alcohol-related hepatocellular carcinoma and influences xenograft tumor growth

Wey-Ran Lin, Ming-Wei Lai, Chau-Ting Yeh
Pages: 903-910
Published online on: 24 December 2012

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Article Open Access

Efficacy of 5-aminolevulinic acid-mediated photodynamic therapy using light-emitting diodes in human colon cancer cells

Tomoya Hatakeyama, Yasutoshi Murayama, Shuhei Komatsu, Atsushi Shiozaki, Yoshiaki Kuriu, Hisashi Ikoma, Masayoshi Nakanishi, Daisuke Ichikawa, Hitoshi Fujiwara, Kazuma Okamoto, Toshiya Ochiai, Yukihito Kokuba, Katsushi Inoue, Motowo Nakajima, Eigo Otsuji
Pages: 911-916
Published online on: 03 January 2013

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Article Open Access

The combination of sorafenib and radiation preferentially inhibits breast cancer stem cells by suppressing HIF-1α expression

Jae Ho Lee, Jae Woong Shim, Yoo Jin Choi, Kyu Heo, Kwangmo Yang
Pages: 917-924
Published online on: 08 January 2013

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Article Open Access

Metabolomic analysis of dynamic response and drug resistance of gastric cancer cells to 5-fluorouracil

Shinsuke Sasada, Yoshihiro Miyata, Yasuhiro Tsutani, Naohiro Tsuyama, Tsutomu Masujima, Jun Hihara, Morihito Okada
Pages: 925-931
Published online on: 11 December 2012

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Article

Podoplanin overexpression in human mesothelioma cell lines enhances the tumorigenic phenotype

Ei Yamaki, Toshiki Yajima, Takayuki Kosaka, Akira Mogi, Shigebumi Tanaka, Hiroyuki Kuwano
Pages: 932-940
Published online on: 04 January 2013

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Article

Effectiveness of sulforaphane as a radiosensitizer for murine osteosarcoma cells

Yasushi Sawai, Hiroaki Murata, Motoyuki Horii, Kazutaka Koto, Takaaki Matsui, Naoyuki Horie, Yoshiro Tsuji, Eishi Ashihara, Taira Maekawa, Toshikazu Kubo, Shinji Fushiki
Pages: 941-945
Published online on: 18 December 2012

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Article

Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma

Masahisa Ishibashi, Ryunosuke Kogo, Kohei Shibata, Genta Sawada, Yusuke Takahashi, Junji Kurashige, Sayuri Akiyoshi, Shin Sasaki, Takeshi Iwaya, Tomoya Sudo, Keishi Sugimachi, Koshi Mimori, Go Wakabayashi, Masaki Mori
Pages: 946-950
Published online on: 28 December 2012

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Article

Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer

Norimasa Matsushita, Atsushi Aruga, Yuji Inoue, Yoshihito Kotera, Kazuyoshi Takeda, Masakazu Yamamoto
Pages: 951-959
Published online on: 10 January 2013

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Article

Cytotoxic effects of adenovirus- and lentivirus-mediated expression of Drosophila melanogaster deoxyribonucleoside kinase on Bcap37 breast cancer cells

Nianqu Zhang, Xiaoshen Dong, Yiqun Sun, Xiaopeng Cai, Caiwei Zheng, Anning He, Ke Xu, Xinyu Zheng
Pages: 960-966
Published online on: 18 December 2012

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Article

Bmi1 gene silencing inhibits the proliferation and invasiveness of human hepatocellular carcinoma cells and increases their sensitivity to 5-fluorouracil

Rui Zhang, Lei-Bo Xu, Xiu-Jing Yue, Xian-Huan Yu, Jie Wang, Chao Liu
Pages: 967-974
Published online on: 14 December 2012

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Article

Chemokine CXCL16 suppresses liver metastasis of colorectal cancer via augmentation of tumor-infiltrating natural killer T cells in a murine model

Ji-Ye Kee, Aya Ito, Shozo Hojo, Isaya Hashimoto, Yoshiko  Igarashi, Kazuhiro  Tsukada, Tatsuro Irimura, Naotoshi Shibahara, Takashi  Nakayama, Osamu  Yoshie, Hiroaki Sakurai, Ikuo Saiki, Keiichi Koizumi
Pages: 975-982
Published online on: 13 December 2012

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Article

Diarylquinoline compounds induce autophagy-associated cell death by inhibiting the Akt pathway and increasing reactive oxygen species in human nasopharyngeal carcinoma cells

Yuchen Cai, Zhihui Wan, Tiemin Sun, Yanxia Shi, Yueli Sun, Peiyu Huang, Su Li, Wenqi Jiang
Pages: 983-992
Published online on: 24 December 2012

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Article

Possible regulatory role of Snail in NF-κB-mediated changes in E-cadherin in gastric cancer

Zenan Hu, Xiaojun Liu, Zhifeng Tang, Yongning Zhou, Liang Qiao
Pages: 993-1000
Published online on: 19 December 2012

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Article

Enhancement of antitumor immunity by combining anti-cytotoxic T lymphocyte antigen-4 antibodies and cryotreated tumor lysate-pulsed dendritic cells in murine osteosarcoma

Masanori Kawano, Ichiro Itonaga, Tatsuya Iwasaki, Hiroshi Tsumura
Pages: 1001-1006
Published online on: 04 January 2013

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Article

PDCD4 functions as a suppressor for pT2a and pT2b stage gastric cancer

Peng-Tao Guo, Dong Yang, Zhe Sun, Hui-Mian Xu
Pages: 1007-1012
Published online on: 11 January 2013

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Article

A new approach to screening cancer stem cells from the U251 human glioma cell line based on cell growth state

Xiangmei Cao, Yu Gu, Lina Jiang, Yingmei Wang, Fang Liu, Yuqiao Xu, Junxia Deng, Yayun Nan, Liying Zhang, Jing Ye, Qing Li
Pages: 1013-1018
Published online on: 21 December 2012

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Article

Lentivirus-mediated shRNA interference targeting vascular endothelial growth factor inhibits angiogenesis and progression of human pancreatic carcinoma

Xin Zhao, Dong-Ming Zhu, Wen-Juan Gan, Zhi Li, Jiang-Lei Zhang, Hua Zhao, Jin Zhou, De-Chun Li
Pages: 1019-1026
Published online on: 19 December 2012

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Article

miR-34a inhibits the metastasis of osteosarcoma cells by repressing the expression of CD44

Haien Zhao, Baoan Ma, Yucai Wang, Tao Han, Lianhe Zheng, Cong Sun, Tao Liu, Yinglong Zhang, Xiuchun Qiu, Qingyu Fan
Pages: 1027-1036
Published online on: 11 January 2013

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Article

RNAi-mediated EZH2 depletion decreases MDR1 expression and sensitizes multidrug-resistant hepatocellular carcinoma cells to chemotherapy Retraction in /10.3892/or.2024.8809

Bo Tang, Yi Zhang, Rui Liang, Zhenming Gao, Deguang Sun, Liming Wang
Pages: 1037-1042
Published online on: 04 January 2013

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Article

Analysis of PIK3CA exon 9 and 20 mutations in breast cancers using PCR-HRM and PCR-ARMS: Correlation with clinicopathological criteria

Alexandre Harlé, Maëva Lion, Nicolas Lozano, Marie Husson, Valentin Harter, Pascal Genin, Jean-Louis Merlin
Pages: 1043-1052
Published online on: 08 January 2013

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Article

Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells

Fang-Ming Hung, Yung-Liang Chen, An-Cheng Huang, Yu-Ping Hsiao, Jai-Sing Yang, Ming-Teng Chung, Fu-Shin Chueh, Hsu-Feng Lu, Jing-Gung Chung
Pages: 1053-1060
Published online on: 08 January 2013

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Article

The properties of human CD40-activated B cells as antigen-presenting cells are not affected by PGE2

Alexander Shimabukuro-Vornhagen, Andreas Draube, Tanja Liebig, Alexey Popov, Achim Rothe, Michael von Bergwelt-Baildon
Pages: 1061-1065
Published online on: 28 December 2012

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Article

Knockdown of Coronin-1C disrupts Rac1 activation and impairs tumorigenic potential in hepatocellular carcinoma cells

Zhi-Gang Wang, Ming-Ku Jia, Hong Cao, Peng Bian, Xue-Dong Fang
Pages: 1066-1072
Published online on: 28 December 2012

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Article

DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells

Ken-Ichi Yamamoto, Hitoshi Murata, Endy Widya Putranto, Ken Kataoka, Akira Motoyama, Toshihiko Hibino, Yusuke Inoue, Masakiyo Sakaguchi, Nam-Ho Huh
Pages: 1073-1079
Published online on: 17 December 2012

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Article

Jiedu Xiaozheng Yin, a Chinese herbal formula, inhibits tumor angiogenesis via downregulation of VEGF-A and VEGFR-2 expression in vivo and in vitro

Zhiyun Cao, Wei Lin, Zhengrong Huang, Xuzheng Chen, Jinyan Zhao, Liangpu Zheng, Hongzhi Ye, Zhizhen Liu, Lianming Liao, Jian Du
Pages: 1080-1086
Published online on: 19 December 2012

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Article

Short hairpin RNA targeting autotaxin reduces human gastric carcinoma AGS cell proliferative, migratory and invasive capabilities in vitro and causes tumor regression in vivo

Zhouxun Chen, Yingpeng Huang, Xian Shen, Jian Guo, Guanbao Zhu, Henning Dralle, Cuong Hoang-Vu
Pages: 1087-1093
Published online on: 20 December 2012

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Article

Effect of PF-02341066 and radiation on non-small cell lung cancer cells

Vasu Tumati, Subashri Kumar, Lan Yu, Benjamin Chen, Hak Choy, Debabrata Saha
Pages: 1094-1100
Published online on: 18 December 2012

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Article

Inhibition of xenograft human glioma tumor growth by lentivirus-mediated gene transfer of alphastatin

Hongmin Che, Jianrong Song, Shiwen Guo, Weiwen Wang, Guodong Gao
Pages: 1101-1107
Published online on: 14 December 2012

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Article

The oncolytic herpes simplex virus vector G47∆ effectively targets breast cancer stem cells

Weigen Zeng, Pan Hu, Juekun Wu, Jiani Wang, Junjie Li, Lan Lei, Renbin Liu
Pages: 1108-1114
Published online on: 24 December 2012

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Article

Overexpression of LASP1 is associated with proliferation, migration and invasion in esophageal squamous cell carcinoma

Bin He, Bangliang Yin, Baoxiang Wang, Chen Chen, Zhenkun Xia, Jingqun Tang, Yunchang Yuan, Xiang Feng, Ni Yin
Pages: 1115-1123
Published online on: 19 December 2012

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Article

Hedgehog signaling pathway regulates human pancreatic cancer cell proliferation and metastasis

Kun Hao, Xiao-Dong Tian, Chang-Fu Qin, Xue-Hai Xie, Yin-Mo Yang
Pages: 1124-1132
Published online on: 24 December 2012

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Article

Suppression of HER-2 via siRNA interference promotes apoptosis and decreases metastatic potential of SKOV‑3 human ovarian carcinoma cells

Yan-Ming Lu, Meng-Li Rong, Chao Shang, Ning Wang, Xiang Li, Yan-Yan Zhao, Shu-Lan Zhang
Pages: 1133-1139
Published online on: 28 December 2012

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Article

Y-39983 downregulates RhoA/Rho-associated kinase expression during its promotion of axonal regeneration

Zijian Yang, Jing Wang, Xiaohong Liu, Yu Cheng, Lianfu Deng, Yisheng Zhong
Pages: 1140-1146
Published online on: 20 December 2012

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Article

Suppression of carbonic anhydrase IX leads to aberrant focal adhesion and decreased invasion of tumor cells

Peter Radvak, Marko Repic, Eliska Svastova, Martina Takacova, Lucia Csaderova, Hynek Strnad, Jaromir Pastorek, Silvia Pastorekova, Juraj Kopacek
Pages: 1147-1153
Published online on: 04 January 2013

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Article

FAM172A induces S phase arrest of HepG2 cells via Notch 3 Retraction in /10.3892/or.2023.8554

Zhiqiang Feng, Hongqi Li, Shunai Liu, Jun Cheng, Guoan Xiang, Jinqian Zhang
Pages: 1154-1160
Published online on: 11 January 2013

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Article

ErbB3-binding protein EBP1 decreases ErbB2 levels via a transcriptional mechanism

Arundhati Ghosh, Smita Awasthi, Anne W. Hamburger
Pages: 1161-1166
Published online on: 14 December 2012

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Article

Local radiotherapy increases the level of autoantibodies to ribosomal P0 protein but not to heat shock proteins, extracellular matrix molecules and EGFR/ErbB2 receptors in prostate cancer patients

Gianluca Ingrosso, Massimo Fantini, Alessandra Nardi, Monica Benvenuto, Pamela  Sacchetti, Laura Masuelli, Elisabetta Ponti, Giovanni Vanni Frajese, Florigio  Lista, Orazio Schillaci, Riccardo Santoni, Andrea Modesti, Roberto Bei
Pages: 1167-1174
Published online on: 18 December 2012

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Article

Screening of candidate tumor-suppressor genes in 3p21.3 and investigation of the methylation of gene promoters in oral squamous cell carcinoma

Kai Wang, Tianyou Ling, Hanjiang Wu, Jie Zhang
Pages: 1175-1182
Published online on: 28 December 2012

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Article

siRNA targeting survivin inhibits the growth and enhances the chemosensitivity of hepatocellular carcinoma cells

Wensong Liu, Feng Zhu, Yong Jiang, Donglin Sun, Bo Yang, Haijiao Yan
Pages: 1183-1188
Published online on: 18 December 2012

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Article

Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells

Giovanni Luca Gravina, Guido Ranieri, Paola Muzi, Francesco  Marampon, Andrea Mancini, Boris Di Pasquale, Luigi Di Clemente, Vincenza  Dolo, Anna Maria D'Alessandro, Claudio Festuccia
Pages: 1189-1195
Published online on: 18 December 2012

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Article

Photodynamic treatment induces cell death by apoptosis or autophagy depending on the melanin content in two B16 melanoma cell lines

Agnès Sparsa, Solenn Bellaton, Thomas Naves, Marie-Odile Jauberteau, Jean-Marie Bonnetblanc, Vincent Sol, Mireille Verdier, Marie-Hélène Ratinaud
Pages: 1196-1200
Published online on: 14 December 2012

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Article

Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5

Zakir Hossain, Tatsuya Sugawara, Takashi Hirata
Pages: 1201-1207
Published online on: 04 January 2013

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Article

Synergistic antitumor effect of JAWSII dendritic cells and interleukin 12 in a melanoma mouse model

Łukasz Zapała, Rafał Wolny, Małgorzata Wachowska, Marek Jakóbisiak, Witold Lasek
Pages: 1208-1214
Published online on: 18 December 2012

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Article

Effects of morin on the pharmacokinetics of etoposide in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female Sprague-Dawley rats

Si Hyung Yang, Hyeon Gyeom Choi, Soo-Jeong Lim, Myung Gull Lee, So Hee Kim
Pages: 1215-1223
Published online on: 19 December 2012

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Article

Differential susceptibility of gastric cancer cells to TRAIL-induced apoptosis

Nak-Mi Song, Suyeon Jun, Dae Young Zang, Sung Gyun Kim, Hye-Rim Park, Dongchul Kang
Pages: 1224-1230
Published online on: 11 December 2012

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Article

Suppression of TPA-induced tumor cell invasion by sulfuretin via inhibition of NF-κB-dependent MMP-9 expression

Jeong-Mi Kim, Eun-Mi Noh, Kang-Beom Kwon, Jong-Suk Kim, Yong-Ouk You, Jin-Ki Hwang, Bo-Mi Hwang, Min Seuk Kim, Seung-Jin Lee, Sung-Hoo Jung, Hyun-Jo Youn, Eun-Yong Chung, Young-Rae Lee
Pages: 1231-1237
Published online on: 28 December 2012

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Article

Inhibition of lymphangiogenic factor VEGF-C expression and production by the histone deacetylase inhibitor suberoylanilide hydroxamic acid in breast cancer cells

Hsueh-Tsen Cheng, Wen-Chun Hung
Pages: 1238-1244
Published online on: 14 December 2012

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Article

T-18, a stemonamide synthetic intermediate inhibits Pim kinase activity and induces cell apoptosis, acting as a potent anticancer drug

Zhen Wang, Xing-Min Li, Kun Shang, Peng Zhang, Chao-Fu Wang, Yu-Hu Xin, Lu Zhou, Ying-Yi Li
Pages: 1245-1251
Published online on: 11 January 2013

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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