Journal Articles

Open Access

New candidate therapeutic agents for endometrial cancer: Potential for clinical practice (Review)

Kiyoko Umene, Kouji Banno, Iori Kisu, Megumi Yanokura, Yuya Nogami, Kosuke Tsuji, Kenta Masuda, Arisa Ueki, Yusuke Kobayashi, Wataru Yamagami, Eiichiro Tominaga, Nobuyuki Susumu, Daisuke Aoki

Pages: 855-860 Published online on: 03 January 2013

Pathogenesis and malignant transformation of adenomyosis (Review)

Natsuki Koike, Taihei Tsunemi, Chiharu Uekuri, Juria Akasaka, Fuminori Ito, Aiko Shigemitsu, Hiroshi Kobayashi

Pages: 861-867 Published online on: 13 December 2012
Open Access

Effects of the activated mitogen-activated protein kinase pathway via the c-ros receptor tyrosine kinase on the T47D breast cancer cell line following alcohol exposure

Hyung Tae Lee, Se Kye Kim, Mi Ran Choi, Ji Hyun Park, Kyoung Hwa Jung, Young Gyu Chai

Pages: 868-874 Published online on: 24 December 2012
Open Access

Oxidative stress-induced 1, N6-ethenodeoxyadenosine adduct formation contributes to hepatocarcinogenesis

Lei Zhou, Yuzhen Yang, Dean Tian, Ying Wang

Pages: 875-884 Published online on: 04 January 2013
Open Access

Retinoic acid inhibits the cytoproliferative response to weak 50‑Hz magnetic fields in neuroblastoma cells

María Ángeles Trillo, María Antonia Martínez, María Antonia Cid, Alejandro Úbeda

Pages: 885-894 Published online on: 24 December 2012
Open Access

The combination of an oxygen-dependent degradation domain-regulated adenovirus expressing the chemokine RANTES/CCL5 and NK-92 cells exerts enhanced antitumor activity in hepatocellular carcinoma

Jiang Li, Hui Liu, Linfang Li, Hongping Wu, Chunhong Wang, Zi Yan, Ying Wang, Changqing Su, Huajun Jin, Fuping Zhou, Mengchao Wu, Qijun Qian

Pages: 895-902 Published online on: 28 December 2012
Open Access

Efficacy of 5-aminolevulinic acid-mediated photodynamic therapy using light-emitting diodes in human colon cancer cells

Tomoya Hatakeyama, Yasutoshi Murayama, Shuhei Komatsu, Atsushi Shiozaki, Yoshiaki Kuriu, Hisashi Ikoma, Masayoshi Nakanishi, Daisuke Ichikawa, Hitoshi Fujiwara, Kazuma Okamoto, Toshiya Ochiai, Yukihito Kokuba, Katsushi Inoue, Motowo Nakajima, Eigo Otsuji

Pages: 911-916 Published online on: 03 January 2013
Open Access

The combination of sorafenib and radiation preferentially inhibits breast cancer stem cells by suppressing HIF-1α expression

Jae Ho Lee, Jae Woong Shim, Yoo Jin Choi, Kyu Heo, Kwangmo Yang

Pages: 917-924 Published online on: 08 January 2013
Open Access

Metabolomic analysis of dynamic response and drug resistance of gastric cancer cells to 5-fluorouracil

Shinsuke Sasada, Yoshihiro Miyata, Yasuhiro Tsutani, Naohiro Tsuyama, Tsutomu Masujima, Jun Hihara, Morihito Okada

Pages: 925-931 Published online on: 11 December 2012

Podoplanin overexpression in human mesothelioma cell lines enhances the tumorigenic phenotype

Ei Yamaki, Toshiki Yajima, Takayuki Kosaka, Akira Mogi, Shigebumi Tanaka, Hiroyuki Kuwano

Pages: 932-940 Published online on: 04 January 2013

Effectiveness of sulforaphane as a radiosensitizer for murine osteosarcoma cells

Yasushi Sawai, Hiroaki Murata, Motoyuki Horii, Kazutaka Koto, Takaaki Matsui, Naoyuki Horie, Yoshiro Tsuji, Eishi Ashihara, Taira Maekawa, Toshikazu Kubo, Shinji Fushiki

Pages: 941-945 Published online on: 18 December 2012

Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma

Masahisa Ishibashi, Ryunosuke Kogo, Kohei Shibata, Genta Sawada, Yusuke Takahashi, Junji Kurashige, Sayuri Akiyoshi, Shin Sasaki, Takeshi Iwaya, Tomoya Sudo, Keishi Sugimachi, Koshi Mimori, Go Wakabayashi, Masaki Mori

Pages: 946-950 Published online on: 28 December 2012

Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer

Norimasa Matsushita, Atsushi Aruga, Yuji Inoue, Yoshihito Kotera, Kazuyoshi Takeda, Masakazu Yamamoto

Pages: 951-959 Published online on: 10 January 2013

Cytotoxic effects of adenovirus- and lentivirus-mediated expression of Drosophila melanogaster deoxyribonucleoside kinase on Bcap37 breast cancer cells

Nianqu Zhang, Xiaoshen Dong, Yiqun Sun, Xiaopeng Cai, Caiwei Zheng, Anning He, Ke Xu, Xinyu Zheng

Pages: 960-966 Published online on: 18 December 2012

Bmi1 gene silencing inhibits the proliferation and invasiveness of human hepatocellular carcinoma cells and increases their sensitivity to 5-fluorouracil

Rui Zhang, Lei-Bo Xu, Xiu-Jing Yue, Xian-Huan Yu, Jie Wang, Chao Liu

Pages: 967-974 Published online on: 14 December 2012

Chemokine CXCL16 suppresses liver metastasis of colorectal cancer via augmentation of tumor-infiltrating natural killer T cells in a murine model

Ji-Ye Kee, Aya Ito, Shozo Hojo, Isaya Hashimoto, Yoshiko  Igarashi, Kazuhiro  Tsukada, Tatsuro Irimura, Naotoshi Shibahara, Takashi  Nakayama, Osamu  Yoshie, Hiroaki Sakurai, Ikuo Saiki, Keiichi Koizumi

Pages: 975-982 Published online on: 13 December 2012

Diarylquinoline compounds induce autophagy-associated cell death by inhibiting the Akt pathway and increasing reactive oxygen species in human nasopharyngeal carcinoma cells

Yuchen Cai, Zhihui Wan, Tiemin Sun, Yanxia Shi, Yueli Sun, Peiyu Huang, Su Li, Wenqi Jiang

Pages: 983-992 Published online on: 24 December 2012

Possible regulatory role of Snail in NF-κB-mediated changes in E-cadherin in gastric cancer

Zenan Hu, Xiaojun Liu, Zhifeng Tang, Yongning Zhou, Liang Qiao

Pages: 993-1000 Published online on: 19 December 2012

Enhancement of antitumor immunity by combining anti-cytotoxic T lymphocyte antigen-4 antibodies and cryotreated tumor lysate-pulsed dendritic cells in murine osteosarcoma

Masanori Kawano, Ichiro Itonaga, Tatsuya Iwasaki, Hiroshi Tsumura

Pages: 1001-1006 Published online on: 04 January 2013

PDCD4 functions as a suppressor for pT2a and pT2b stage gastric cancer

Peng-Tao Guo, Dong Yang, Zhe Sun, Hui-Mian Xu

Pages: 1007-1012 Published online on: 11 January 2013

A new approach to screening cancer stem cells from the U251 human glioma cell line based on cell growth state

Xiangmei Cao, Yu Gu, Lina Jiang, Yingmei Wang, Fang Liu, Yuqiao Xu, Junxia Deng, Yayun Nan, Liying Zhang, Jing Ye, Qing Li

Pages: 1013-1018 Published online on: 21 December 2012

Lentivirus-mediated shRNA interference targeting vascular endothelial growth factor inhibits angiogenesis and progression of human pancreatic carcinoma

Xin Zhao, Dong-Ming Zhu, Wen-Juan Gan, Zhi Li, Jiang-Lei Zhang, Hua Zhao, Jin Zhou, De-Chun Li

Pages: 1019-1026 Published online on: 19 December 2012

miR-34a inhibits the metastasis of osteosarcoma cells by repressing the expression of CD44

Haien Zhao, Baoan Ma, Yucai Wang, Tao Han, Lianhe Zheng, Cong Sun, Tao Liu, Yinglong Zhang, Xiuchun Qiu, Qingyu Fan

Pages: 1027-1036 Published online on: 11 January 2013

RNAi-mediated EZH2 depletion decreases MDR1 expression and sensitizes multidrug-resistant hepatocellular carcinoma cells to chemotherapy

Bo Tang, Yi Zhang, Rui Liang, Zhenming Gao, Deguang Sun, Liming Wang

Pages: 1037-1042 Published online on: 04 January 2013

Analysis of PIK3CA exon 9 and 20 mutations in breast cancers using PCR-HRM and PCR-ARMS: Correlation with clinicopathological criteria

Alexandre Harlé, Maëva Lion, Nicolas Lozano, Marie Husson, Valentin Harter, Pascal Genin, Jean-Louis Merlin

Pages: 1043-1052 Published online on: 08 January 2013

Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells

Fang-Ming Hung, Yung-Liang Chen, An-Cheng Huang, Yu-Ping Hsiao, Jai-Sing Yang, Ming-Teng Chung, Fu-Shin Chueh, Hsu-Feng Lu, Jing-Gung Chung

Pages: 1053-1060 Published online on: 08 January 2013

The properties of human CD40-activated B cells as antigen-presenting cells are not affected by PGE2

Alexander Shimabukuro-Vornhagen, Andreas Draube, Tanja Liebig, Alexey Popov, Achim Rothe, Michael von Bergwelt-Baildon

Pages: 1061-1065 Published online on: 28 December 2012

Knockdown of Coronin-1C disrupts Rac1 activation and impairs tumorigenic potential in hepatocellular carcinoma cells

Zhi-Gang Wang, Ming-Ku Jia, Hong Cao, Peng Bian, Xue-Dong Fang

Pages: 1066-1072 Published online on: 28 December 2012

DOCK7 is a critical regulator of the RAGE-Cdc42 signaling axis that induces formation of dendritic pseudopodia in human cancer cells

Ken-Ichi Yamamoto, Hitoshi Murata, Endy Widya Putranto, Ken Kataoka, Akira Motoyama, Toshihiko Hibino, Yusuke Inoue, Masakiyo Sakaguchi, Nam-Ho Huh

Pages: 1073-1079 Published online on: 17 December 2012

Jiedu Xiaozheng Yin, a Chinese herbal formula, inhibits tumor angiogenesis via downregulation of VEGF-A and VEGFR-2 expression in vivo and in vitro

Zhiyun Cao, Wei Lin, Zhengrong Huang, Xuzheng Chen, Jinyan Zhao, Liangpu Zheng, Hongzhi Ye, Zhizhen Liu, Lianming Liao, Jian Du

Pages: 1080-1086 Published online on: 19 December 2012

Short hairpin RNA targeting autotaxin reduces human gastric carcinoma AGS cell proliferative, migratory and invasive capabilities in vitro and causes tumor regression in vivo

Zhouxun Chen, Yingpeng Huang, Xian Shen, Jian Guo, Guanbao Zhu, Henning Dralle, Cuong Hoang-Vu

Pages: 1087-1093 Published online on: 20 December 2012

Effect of PF-02341066 and radiation on non-small cell lung cancer cells

Vasu Tumati, Subashri Kumar, Lan Yu, Benjamin Chen, Hak Choy, Debabrata Saha

Pages: 1094-1100 Published online on: 18 December 2012

Inhibition of xenograft human glioma tumor growth by lentivirus-mediated gene transfer of alphastatin

Hongmin Che, Jianrong Song, Shiwen Guo, Weiwen Wang, Guodong Gao

Pages: 1101-1107 Published online on: 14 December 2012

The oncolytic herpes simplex virus vector G47∆ effectively targets breast cancer stem cells

Weigen Zeng, Pan Hu, Juekun Wu, Jiani Wang, Junjie Li, Lan Lei, Renbin Liu

Pages: 1108-1114 Published online on: 24 December 2012

Overexpression of LASP1 is associated with proliferation, migration and invasion in esophageal squamous cell carcinoma

Bin He, Bangliang Yin, Baoxiang Wang, Chen Chen, Zhenkun Xia, Jingqun Tang, Yunchang Yuan, Xiang Feng, Ni Yin

Pages: 1115-1123 Published online on: 19 December 2012

Hedgehog signaling pathway regulates human pancreatic cancer cell proliferation and metastasis

Kun Hao, Xiao-Dong Tian, Chang-Fu Qin, Xue-Hai Xie, Yin-Mo Yang

Pages: 1124-1132 Published online on: 24 December 2012

Suppression of HER-2 via siRNA interference promotes apoptosis and decreases metastatic potential of SKOV‑3 human ovarian carcinoma cells

Yan-Ming Lu, Meng-Li Rong, Chao Shang, Ning Wang, Xiang Li, Yan-Yan Zhao, Shu-Lan Zhang

Pages: 1133-1139 Published online on: 28 December 2012

Y-39983 downregulates RhoA/Rho-associated kinase expression during its promotion of axonal regeneration

Zijian Yang, Jing Wang, Xiaohong Liu, Yu Cheng, Lianfu Deng, Yisheng Zhong

Pages: 1140-1146 Published online on: 20 December 2012

Suppression of carbonic anhydrase IX leads to aberrant focal adhesion and decreased invasion of tumor cells

Peter Radvak, Marko Repic, Eliska Svastova, Martina Takacova, Lucia Csaderova, Hynek Strnad, Jaromir Pastorek, Silvia Pastorekova, Juraj Kopacek

Pages: 1147-1153 Published online on: 04 January 2013

FAM172A induces S phase arrest of HepG2 cells via Notch 3

Zhiqiang Feng, Hongqi Li, Shunai Liu, Jun Cheng, Guoan Xiang, Jinqian Zhang

Pages: 1154-1160 Published online on: 11 January 2013

ErbB3-binding protein EBP1 decreases ErbB2 levels via a transcriptional mechanism

Arundhati Ghosh, Smita Awasthi, Anne W. Hamburger

Pages: 1161-1166 Published online on: 14 December 2012

Local radiotherapy increases the level of autoantibodies to ribosomal P0 protein but not to heat shock proteins, extracellular matrix molecules and EGFR/ErbB2 receptors in prostate cancer patients

Gianluca Ingrosso, Massimo Fantini, Alessandra Nardi, Monica Benvenuto, Pamela  Sacchetti, Laura Masuelli, Elisabetta Ponti, Giovanni Vanni Frajese, Florigio  Lista, Orazio Schillaci, Riccardo Santoni, Andrea Modesti, Roberto Bei

Pages: 1167-1174 Published online on: 18 December 2012

Screening of candidate tumor-suppressor genes in 3p21.3 and investigation of the methylation of gene promoters in oral squamous cell carcinoma

Kai Wang, Tianyou Ling, Hanjiang Wu, Jie Zhang

Pages: 1175-1182 Published online on: 28 December 2012

siRNA targeting survivin inhibits the growth and enhances the chemosensitivity of hepatocellular carcinoma cells

Wensong Liu, Feng Zhu, Yong Jiang, Donglin Sun, Bo Yang, Haijiao Yan

Pages: 1183-1188 Published online on: 18 December 2012

Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells

Giovanni Luca Gravina, Guido Ranieri, Paola Muzi, Francesco  Marampon, Andrea Mancini, Boris Di Pasquale, Luigi Di Clemente, Vincenza  Dolo, Anna Maria D'Alessandro, Claudio Festuccia

Pages: 1189-1195 Published online on: 18 December 2012

Photodynamic treatment induces cell death by apoptosis or autophagy depending on the melanin content in two B16 melanoma cell lines

Agnès Sparsa, Solenn Bellaton, Thomas Naves, Marie-Odile Jauberteau, Jean-Marie Bonnetblanc, Vincent Sol, Mireille Verdier, Marie-Hélène Ratinaud

Pages: 1196-1200 Published online on: 14 December 2012

Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5

Zakir Hossain, Tatsuya Sugawara, Takashi Hirata

Pages: 1201-1207 Published online on: 04 January 2013

Synergistic antitumor effect of JAWSII dendritic cells and interleukin 12 in a melanoma mouse model

Łukasz Zapała, Rafał Wolny, Małgorzata Wachowska, Marek Jakóbisiak, Witold Lasek

Pages: 1208-1214 Published online on: 18 December 2012

Effects of morin on the pharmacokinetics of etoposide in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female Sprague-Dawley rats

Si Hyung Yang, Hyeon Gyeom Choi, Soo-Jeong Lim, Myung Gull Lee, So Hee Kim

Pages: 1215-1223 Published online on: 19 December 2012

Differential susceptibility of gastric cancer cells to TRAIL-induced apoptosis

Nak-Mi Song, Suyeon Jun, Dae Young Zang, Sung Gyun Kim, Hye-Rim Park, Dongchul Kang

Pages: 1224-1230 Published online on: 11 December 2012

Suppression of TPA-induced tumor cell invasion by sulfuretin via inhibition of NF-κB-dependent MMP-9 expression

Jeong-Mi Kim, Eun-Mi Noh, Kang-Beom Kwon, Jong-Suk Kim, Yong-Ouk You, Jin-Ki Hwang, Bo-Mi Hwang, Min Seuk Kim, Seung-Jin Lee, Sung-Hoo Jung, Hyun-Jo Youn, Eun-Yong Chung, Young-Rae Lee

Pages: 1231-1237 Published online on: 28 December 2012

T-18, a stemonamide synthetic intermediate inhibits Pim kinase activity and induces cell apoptosis, acting as a potent anticancer drug

Zhen Wang, Xing-Min Li, Kun Shang, Peng Zhang, Chao-Fu Wang, Yu-Hu Xin, Lu Zhou, Ying-Yi Li

Pages: 1245-1251 Published online on: 11 January 2013
Journal Cover

March 2013
Volume 29 Issue 3

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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