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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2016 Volume 38 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

The clinical significance and impact of interleukin 15 on keratinocyte cell growth and migration

A. M. Jones, J. L. Griffiths, A. J. Sanders, S. Owen, F. Ruge, K. G. Harding, W. G. Jiang
Pages: 679-686
Published online on: 21 July 2016

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Article Open Access

Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities

Patrícia Silva, Cristina Albuquerque, Pedro Lage, Vanessa Fontes, Ricardo Fonseca, Inês Vitoriano, Bruno Filipe, Paula Rodrigues, Susana Moita, Sara Ferreira, Rita Sousa, Isabel Claro, Carlos Nobre Leitão, Paula Chaves, António Dias Pereira
Pages: 687-702
Published online on: 05 July 2016

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Article Open Access

RNAi-mediated downregulation of DNA binding protein A inhibits tumorigenesis in colorectal cancer

Rui-Ting Liu, Guo-Rong Wang, Chang Liu, Jian Qiu, Li-Kun Yan, Xiao-Jun Li, Xiao-Qiang Wang
Pages: 703-712
Published online on: 04 July 2016

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Article Open Access

Effects of an intravitreal injection of interleukin-35-expressing plasmid on pro-inflammatory and anti-inflammatory cytokines

Chao Hou, Qianni Wu, Chen Ouyang, Ting Huang
Pages: 713-720
Published online on: 22 July 2016

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Article Open Access

Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ

Shunsuke Tsujimoto, Manabu Kishina, Masahiko Koda, Yasutaka Yamamoto, Kohei Tanaka, Yusuke Harada, Akio Yoshida, Ichiro Hisatome
Pages: 721-728
Published online on: 11 July 2016

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Article Open Access

Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose

Zi-Ying Shen, Qian Sun, Zhong-Yuan Xia, Qing-Tao Meng, Shao-Qing Lei, Bo Zhao, Ling-Hua Tang, Rui Xue, Rong Chen
Pages: 729-736
Published online on: 14 July 2016

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Article Open Access

Knockdown of HMGN2 increases the internalization of Klebsiella pneumoniae by respiratory epithelial cells through the regulation of α5β1 integrin expression

Xinyuan Wang, Jingyu Li, Shanze Chen, Xiaofei Shen, Xiaolong Yang, Yan Teng, Luxia Deng, Yi Wang, Junli Chen, Xiaoying Wang, Ning Huang
Pages: 737-746
Published online on: 25 July 2016

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Article Open Access

Multi-glycoside of Tripterygium wilfordii Hook. f. ameliorates imiquimod-induced skin lesions through a STAT3-dependent mechanism involving the inhibition of Th17-mediated inflammatory responses

Jingxia Zhao, Tingting Di, Yan Wang, Xin Liu, Daiying Liang, Guangzhong Zhang, Ping Li
Pages: 747-757
Published online on: 11 July 2016

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Article Open Access

Sarcolemmal ATP-sensitive potassium channel protects cardiac myocytes against lipopolysaccharide-induced apoptosis

Xiaohui Zhang, Xiaohua Zhang, Yiqun Xiong, Chaoying Xu, Xinliang Liu, Jian Lin, Guiping Mu, Shaogang Xu, Wenhe Liu
Pages: 758-766
Published online on: 05 July 2016

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Article Open Access

The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats

Guofu Li, Jia Jia, Kaiqiang Ji, Xiaoying Gong, Rui Wang, Xiaoli Zhang, Haiyuan Wang, Bin Zang
Pages: 767-775
Published online on: 05 July 2016

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Article Open Access

Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family

Mohammed A. Suliman, Zhenxing Zhang, Heya Na, Ailton L.L. Ribeiro, Yu Zhang, Bachir Niang, Abdu Salim Hamid, Hua Zhang, Lijie Xu, Yunfei Zuo
Pages: 776-784
Published online on: 22 July 2016

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Article Open Access

TERT alleviates irradiation-induced late rectal injury by reducing hypoxia-induced ROS levels through the activation of NF-κB and autophagy

Qi Liu, Yong Sun, Yuefeng Lv, Ziyu Le, Yuhu Xin, Ping Zhang, Yong Liu
Pages: 785-793
Published online on: 11 July 2016

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Article Open Access

Effects of ghrelin on the apoptosis of human neutrophils in vitro

Bin Li, Mian Zeng, Haichong Zheng, Chunrong Huang, Wanmei He, Guifang Lu, Xia Li, Yanzhu Chen, Ruijie Xie
Pages: 794-802
Published online on: 06 July 2016

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Article Open Access

Ubiquitin-specific protease 4 inhibits breast cancer cell growth through the upregulation of PDCD4 Retraction in /10.3892/ijmm.2024.5417

Yang Li, Daqing Jiang, Qi Zhang, Xiaoli Liu, Zhengang Cai
Pages: 803-811
Published online on: 19 July 2016

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Article Open Access

Histone deacetylase inhibitors suppress RSV infection and alleviate virus-induced airway inflammation

Qiuqin Feng, Zhonglan Su, Shiyu Song, Hui Χu, Bin Zhang, Long Yi, Man Tian, Hongwei Wang
Pages: 812-822
Published online on: 26 July 2016

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Article Open Access

A potential target gene for the host-directed therapy of mycobacterial infection in murine macrophages

Zhang Bao, Ran Chen, Pei Zhang, Shan Lu, Xing Chen, Yake Yao, Xiaozheng Jin, Yilan Sun, Jianying Zhou
Pages: 823-833
Published online on: 11 July 2016

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Article

Picrasma quassiodes (D. Don) Benn. attenuates lipopolysaccharide (LPS)-induced acute lung injury

Jae-Won Lee, Ji-Won Park, Na-Rae Shin, So-Yeon Park, Ok-Kyoung Kwon, Hyun Ah Park, Yourim Lim, Hyung Won Ryu, Heung Joo Yuk, Jung Hee Kim, Sei-Ryang Oh, Kyung-Seop Ahn
Pages: 834-844
Published online on: 07 July 2016

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Article

miR-696 plays a role in hepatic gluconeogenesis in ob/ob mice by targeting PGC-1α

Zhijuan Fang, Peng Li, Wenhui Jia, Ting Jiang, Zhongyun Wang, Yang Xiang
Pages: 845-852
Published online on: 01 July 2016

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Article

Identification of NR0B1 as a novel androgen receptor co-repressor in mouse Sertoli cells

Yu-Chi Li, Man-Ling Luo, Huan Guo, Tian-Tian Wang, Shou-Ren Lin, Jian-Bo Chen, Qian Ma, Yan-Li Gu, Zhi-Mao Jiang, Yao-Ting Gui
Pages: 853-860
Published online on: 11 July 2016

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Article

Curcumin exerts antitumor effects in retinoblastoma cells by regulating the JNK and p38 MAPK pathways

Xiaoming Yu, Jingtao Zhong, Li Yan, Jie Li, Hui Wang, Yan Wen, Yu Zhao
Pages: 861-868
Published online on: 13 July 2016

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Article

Effects of caffeic acid on learning deficits in a model of Alzheimer's disease

Yunliang Wang, Yutong Wang, Jinfeng Li, Linlin Hua, Bing Han, Yuzhen Zhang, Xiaopeng Yang, Zhilei Zeng, Hongying Bai, Honglei Yin, Jiyu Lou
Pages: 869-875
Published online on: 18 July 2016

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Article

DEC2 is a negative regulator for the proliferation and differentiation of chondrocyte lineage-committed mesenchymal stem cells

Tomoko Sasamoto, Katsumi Fujimoto, Masami Kanawa, Junko Kimura, Junpei Takeuchi, Naoko Harada, Noriko Goto, Takeshi Kawamoto, Mitsuhide Noshiro, Ketut Suardita, Kazuo Tanne, Yukio Kato
Pages: 876-884
Published online on: 01 July 2016

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Article

Radioprotective 105 kDa protein attenuates ischemia/reperfusion-induced myocardial apoptosis and autophagy by inhibiting the activation of the TLR4/NF-κB signaling pathway in rats

Xin Guo, Hong Jiang, Jun Yang, Jing Chen, Jian Yang, Jia-Wang Ding, Song Li, Hui Wu, Hua-Sheng Ding
Pages: 885-893
Published online on: 19 July 2016

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Article

Transcriptomic changes in human renal proximal tubular cells revealed under hypoxic conditions by RNA sequencing

Wenmin Yu, Yiping Li, Zhi Wang, Lei Liu, Jing Liu, Fengan Ding, Xiaoyi Zhang, Zhengyuan Cheng, Pingsheng Chen, Jun Dou
Pages: 894-902
Published online on: 13 July 2016

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Article

Targeted blockade of JAK/STAT3 signaling inhibits proliferation, migration and collagen production as well as inducing the apoptosis of hepatic stellate cells

Yuan-Jing Gu, Wu-Yi Sun, Sen Zhang, Xin-Ran Li, Wei Wei
Pages: 903-911
Published online on: 26 July 2016

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Article

Benzyl isothiocyanate inhibits inflammasome activation in E. coli LPS-stimulated BV2 cells

Chang-Min Lee, Dae-Sung Lee, Won-Kyo Jung, Jong Su Yoo, Mi-Jin Yim, Yung Hyun Choi, Saegwang Park, Su-Kil Seo, Jung Sik Choi, Young-Min Lee, Won Sun Park, Il-Whan Choi
Pages: 912-918
Published online on: 06 July 2016

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Article

A single nucleotide polymorphism in the 3'-untranslated region of the KRAS gene disrupts the interaction with let-7a and enhances the metastatic potential of osteosarcoma cells

Shiqian Zhang, Chunying Hou, Guojun Li, Yang Zhong, Jie Zhang, Xinzhen Guo, Baoxin Li, Zhenggang Bi, Ming Shao
Pages: 919-926
Published online on: 04 July 2016

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Article

piR-651 promotes tumor formation in non-small cell lung carcinoma through the upregulation of cyclin D1 and CDK4

Dan Li, Yingquan Luo, Yawen Gao, Yue Yang, Yina Wang, Yan Xu, Shengyu Tan, Yuwei Zhang, Juan Duan, Yu Yang
Pages: 927-936
Published online on: 11 July 2016

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Article

Influence of cartilage interstitial fluid on the mRNA levels of matrix proteins, cytokines, metalloproteases and their inhibitors in synovial membrane

Anna Hyc, Stanislaw Moskalewski, Anna Osiecka-Iwan
Pages: 937-942
Published online on: 19 July 2016

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Article

Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway

Hong-Yan Gong, Fang Zheng, Chao Zhang, Xi-Yan Chen, Jing-Jing Liu, Xiu-Qin Yue
Pages: 943-950
Published online on: 05 July 2016

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Article

Development of a SYBR-Green Ⅰ quantitative PCR assay for the detection and genotyping of different hantaviruses

Ziyu Liu, Fang Wang, Lijuan Yuan, Xiaoxiao Zhang, Qikang Ying, Lan Yu, Liang Zhang, Linfeng Cheng, Fanglin Zhang, Jianguo Lu, Xing'an Wu
Pages: 951-960
Published online on: 13 July 2016

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Article

The peroxisome proliferator-activated receptor α agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes: Correlation with serum ALT levels

Petra Thulin, Krister Bamberg, Marcin Buler, Björn Dahl, Björn Glinghammar
Pages: 961-968
Published online on: 14 July 2016

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Article

Adenosine and the adenosine A2A receptor agonist, CGS21680, upregulate CD39 and CD73 expression through E2F-1 and CREB in regulatory T cells isolated from septic mice

Rui Bao, Xianqi Shui, Jiong Hou, Jinbao Li, Xiaoming Deng, Xiaoyan Zhu, Tao Yang
Pages: 969-975
Published online on: 14 July 2016

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Correction Open Access

[Corrigendum] Jumonji AT-rich interactive domain 1B overexpression is associated with the development and progression of glioma

Liping Fang, Jiuhan Zhao, Dan Wang, Liyu Zhu, Jian Wang, Kui Jiang
Pages: 976-976
Published online on: 15 July 2016

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Journal Cover
July-2026 Volume 58 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Sex differences in cardiovascular‑kidney‑metabolic syndrome: From pathogenesis to treatment response (Review)

Yanqin Fan, Hongtu Hu, Jing Cheng
Article Number: 202
Published online on: 27 May 2026

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Retraction Open Access

[Retracted] BAMBI inhibits inflammation through the activation of autophagy in experimental spinal cord injury

Yin Yang, Chunyang Guo, Bo Liao, Junjun Cao, Chen Liang, Xijing He
Article Number: 201
Published online on: 25 May 2026

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Article Open Access

Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 200
Published online on: 22 May 2026

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Article Open Access

Ginsenoside Rg3 potentiates cisplatin antitumor activity while mitigating nephrotoxicity through SIRT1‑mediated suppression of the NLRP3 inflammasome

Jinghui Zhai, Yueming Zhang, Jiawei Gong, Li Fu, Sixi Zhang
Article Number: 199
Published online on: 22 May 2026

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Article Open Access

Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning

Qiming Xu, Chunjing Xu, Ziyang Liu, Jianrao Lu, Jing Hu, Lin Liao
Article Number: 198
Published online on: 21 May 2026

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Article Open Access

CTRP3 alleviates neuropathic pain by improving mitochondrial biogenesis and mitochondrial unfolded protein response via spinal SIRT1 in rats

Tianzhu Liu, Longqing Zhang, Wei Mei
Article Number: 197
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Article Number: 196
Published online on: 20 May 2026

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Article Open Access

Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice

Xin Jin, Xuan Liu, Yun-Juan Wang, Zi-Li Lei, Yan-Hong Yang
Article Number: 195
Published online on: 20 May 2026

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Article Open Access

Endothelial NOX4‑driven oxidative stress inhibition reverses HtrA1 deficiency‑induced blood‑brain barrier disruption and cognitive impairment

Shi-Na Song, Jun-Ying Wu, Mao-Mei Song, Xiao-Feng Li, Jian-Ming Wang, Wen-Hui Jia, Chang-Xin Li, Sui-Yi Xu
Article Number: 194
Published online on: 19 May 2026

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Review Open Access

Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review)

Sen Chen, Xiaofei Cui
Article Number: 193
Published online on: 19 May 2026

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Review Open Access

Unraveling the molecular landscape of chronic radiation injury: From oxidative stress signaling to translational modeling (Review)

Zhenjun Xi, Xiaodong Li, Chunhui Yang, Li Wang, Jingxin Mao, Qianqian Liu, Chang Liu, Qian Li, Yuanfang Hou, Jie Wan, Chengzhuo Yang, Feiji Sun, Chao Yu, Miao Wang, Baocheng Yuan, Yongsheng Liu, Qing Hu, Li Zhang, Xuemei Li, Xiaobing Li
Article Number: 192
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Cocktail therapy with a combination of interferon, ribavirin and angiotensin‑II type 1 receptor blocker attenuates murine liver fibrosis development

Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Kosuke Kaji, Yosuke Aihara, Yusaku Shirai, Junichi Yoshii, Koji Yanase, Hiroshi Fukui
Article Number: 191
Published online on: 18 May 2026

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Review Open Access

Autophagy and metabolic homeostasis: Exploration in obesity‑related metabolic diseases (Review)

Chenglin Lu, Xiangyu Qi, Yuting Tong, Peng Lu, Dandan Luo, Qingbo Guan, Chunxiao Yu
Article Number: 190
Published online on: 14 May 2026

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Review Open Access

Primary cilia dysfunction: A critical driver of metabolic diseases (Review)

Xiaojing Wang, Yi Jin, Kejia Xie, Pengfei Yao, Liguo Song, Hongdan Liu, Yanjie Tan
Article Number: 189
Published online on: 14 May 2026

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Review Open Access

Gut‑brain axis in anesthesia and critical illness: Molecular crosstalk and its impact on delirium and outcome (Review)

Xigang Ma, Yongsen Zhao
Article Number: 188
Published online on: 14 May 2026

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Article Open Access

Betulinic acid alleviates the inflammatory injury of osteoblasts in osteoporosis by augmenting autophagy via the AMPK-mTOR signaling pathway

Yiwei Zhao, Zechao Qu, Lin Liu, Yong Zhang, Xiaohao Wang, Bo Zhang, Yining Gong, Liang Yan
Article Number: 187
Published online on: 13 May 2026

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Correction Open Access

[Corrigendum] Induction of cardiomyocyte‑like cells from hair follicle cells in mice

Yong-Hee Kim, Bang-Jin Kim, Seok-Man Kim, Sun-Uk Kim, Buom-Yong Ryu
Article Number: 186
Published online on: 13 May 2026

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Review Open Access

Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review)

Guiqing Chen, Hongyan Jia, Kai Zhao, Chang Gao, Yue Liu, Hong Zhu, Dakai Yang, Yun Cai
Article Number: 185
Published online on: 13 May 2026

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Article Open Access

Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms

Hui Fang, Min Shu, Jiaju Wang, Heng Tian, Jianguo Zhang, Ying Hu, He Li, Huan Zhou, Kangsheng Gu, Zhenhua Ren
Article Number: 184
Published online on: 12 May 2026

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Review Open Access

Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review)

Chengyi Ming, Ni Zhu, You Yu, Hong Zhou, Meichun Hu
Article Number: 183
Published online on: 12 May 2026

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Review Open Access

Rab27: Molecular switch of tumor exosome secretion (Review)

Mengtian Tang, Zhongjian Zhu, Huaxin Duan, Shiming Tan, Mengzhou Shen, Xianjie Jiang, Qiu Peng, Linda Oyang, Zongyao Ren, Yujuan Zhou, Qianjin Liao
Article Number: 182
Published online on: 12 May 2026

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Article Open Access

IL‑17A+ γδT cell activation via the HMGB1‑TLR2/4‑NF‑κB signaling pathways in biliary atresia

Meng-Xin Zhang, Jing-Feng Tang, Mei Hong, Ying Yang, Yun Zhou, Shui-Qing Chi, Li-Ying Rong, Guo-Qing Cao, Xi Zhang, Jin-Xiang Zhang, Shao-Tao Tang
Article Number: 181
Published online on: 11 May 2026

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CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis

Lumeng Song, Ping Xiong, Amu Jike, Xiaochao Xia, Lifang Mao, Zihao Wang, Yinchuan Cheng, Shumin Wang, Shizheng Tan, Dongnan Yu, Zheng Li, Xiaoping Tang, Shun Li
Article Number: 180
Published online on: 11 May 2026

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Correction Open Access

[Corrigendum] Expression of FKBP52 in the ovaries of PCOS rats

Shiyan Song, Yong Tan
Article Number: 179
Published online on: 11 May 2026

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miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis

Xiaoyu Wang, Lin Song, Jiafeng Wang, Qianqian Xie, Yan Wang, Chunyan Li, Tianqi Wang, Yifeng Du
Article Number: 178
Published online on: 08 May 2026

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Review Open Access

Radiotherapy and cytokines: A systems view of immunotherapy and toxicity (Review)

Siyuan Zhou, Yurong Jiang, Jixu Fan, Minjie Guo, Yi Wen, Chunhua Dai
Article Number: 177
Published online on: 08 May 2026

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Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)

Xiwei Wang, Shuang Li, Xiaotian Ge, Tao Xie, Sainan Li, Ruiqi Yuan, Tianxi Li, Hui Yuan
Article Number: 176
Published online on: 06 May 2026

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Expression of Concern Open Access

[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai
Article Number: 175
Published online on: 06 May 2026

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Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)

Ziang Geng, Shu Guan, Shaoqi Du, Shuo Zhang, Jiaxin Hao, Siyuan Tian, Chen Zhu, Shaonan Du
Article Number: 174
Published online on: 06 May 2026

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Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review)

Wenhui Gu, Haifeng Zhang, Lisha Ye, Fangming Liu, Ting Xu, Yinxian Yu, Guohua Wang
Article Number: 173
Published online on: 05 May 2026

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Retraction Open Access

[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Article Number: 172
Published online on: 04 May 2026

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Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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August-2026 Volume 58 Issue 2

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Impact Factor: 5.8

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Effects of exercise‑derived extracellular vesicles: Epigenetic regulatory mechanisms and protective roles (Review)

Xinxin Zhang, Biao Zhang
Article Number: 220
Published online on: 15 June 2026

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Moderate downregulation of NDUFA13 promotes cardiomyocytes proliferation and heart regeneration through the glycolysis/c‑Myc/Ccnd1 axis

Ying Gao, Ningjing Qian, Junyan Jin, Jiayi Liu, Bingqi Wang, Yaping Wang
Article Number: 219
Published online on: 12 June 2026

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[Corrigendum] (‑)‑Epigallocatechin‑3‑gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions

Yang Wu, Zhong-Yuan Xia, Bo Zhao, Yan Leng, Juan Dou, Qing-Tao Meng, Shao-Qing Lei, Zhi-Ze Chen, Jie Zhu
Article Number: 218
Published online on: 10 June 2026

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Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis

Qingtao Yang, Wei Li, Qi Yu, Jiang Shi, Lu Yang, Jun Qiao, Xi Wei, Changshi Gu, Fa Sun, Tao Li
Article Number: 217
Published online on: 09 June 2026

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Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review)

Yaping Wu, Hao Yu, Ling Xia, Li Yang, Yu Zhou, Qian Yu
Article Number: 216
Published online on: 08 June 2026

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Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)

Boying Zhu, Chaoyang Wang, Peng Liu, Zhifeng Qu, Ran Qi, Shengjiang Chen, Huanzhang Niu
Article Number: 215
Published online on: 08 June 2026

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Article Open Access

Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress

Miao Xue, Junshuai Feng, Xiaorong Mao
Article Number: 214
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Article Number: 213
Published online on: 08 June 2026

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Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

Wei Dai, Jiabin Wu, Xiaotong Ma, Mingyu Wu, Ke Li, Haoyang Gao, Wenhong Wang, Weihua Xiao
Article Number: 212
Published online on: 05 June 2026

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Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)

Zheming Yang, Jiayin Li, Lingxiao Zhao, Dali Zhang, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 211
Published online on: 04 June 2026

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Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

Stefanny M. Figueroa, Siyi Huang, Javier Reyes‑Osorio, Jean-Jacques Boffa, Cristián A. Amador, Christos E. Chadjichristos, Louis Boutin
Article Number: 210
Published online on: 04 June 2026

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

Zhanli Yang, Chuntao Yang, Liangcan Xiao, Xinxue Liao, Aiping Lan, Xiuyu Wang, Ruixian Guo, Peixi Chen, Chengheng Hu, Jianqiang Feng
Article Number: 209
Published online on: 03 June 2026

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Article Open Access

Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
Article Number: 208
Published online on: 03 June 2026

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Article Open Access

Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

Zhibo Fan, Qiyue Fu, Tao Sun, Yutong Zhong, Yuefan Ma, Jingwei Jian, Shuosheng Yuan, Shenghong Li, Xiaomei Xu
Article Number: 207
Published online on: 02 June 2026

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Retraction Open Access

[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

Xiaoxu Gao, Yan Cai, Ruifang An
Article Number: 206
Published online on: 02 June 2026

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Review

Multi‑scale experimental models for the study of angiogenesis (Review)

Qin Yu, Jiarui Hu, Shuangshuang Yuan, Jiexia Gan, Mao Luo, Jianbo Wu, Liqun Wang
Article Number: 205
Published online on: 28 May 2026

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Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

Lianting Chen, Feiqiong Gao, Qianru Mei, Yujie Li, Qun Cai, Xudong Feng
Article Number: 204
Published online on: 28 May 2026

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Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
Article Number: 203
Published online on: 28 May 2026

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