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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2016 Volume 38 Issue 3

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

The clinical significance and impact of interleukin 15 on keratinocyte cell growth and migration

A. M. Jones, J. L. Griffiths, A. J. Sanders, S. Owen, F. Ruge, K. G. Harding, W. G. Jiang
Pages: 679-686
Published online on: 21 July 2016

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Article Open Access

Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities

Patrícia Silva, Cristina Albuquerque, Pedro Lage, Vanessa Fontes, Ricardo Fonseca, Inês Vitoriano, Bruno Filipe, Paula Rodrigues, Susana Moita, Sara Ferreira, Rita Sousa, Isabel Claro, Carlos Nobre Leitão, Paula Chaves, António Dias Pereira
Pages: 687-702
Published online on: 05 July 2016

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Article Open Access

RNAi-mediated downregulation of DNA binding protein A inhibits tumorigenesis in colorectal cancer

Rui-Ting Liu, Guo-Rong Wang, Chang Liu, Jian Qiu, Li-Kun Yan, Xiao-Jun Li, Xiao-Qiang Wang
Pages: 703-712
Published online on: 04 July 2016

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Article Open Access

Effects of an intravitreal injection of interleukin-35-expressing plasmid on pro-inflammatory and anti-inflammatory cytokines

Chao Hou, Qianni Wu, Chen Ouyang, Ting Huang
Pages: 713-720
Published online on: 22 July 2016

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Article Open Access

Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ

Shunsuke Tsujimoto, Manabu Kishina, Masahiko Koda, Yasutaka Yamamoto, Kohei Tanaka, Yusuke Harada, Akio Yoshida, Ichiro Hisatome
Pages: 721-728
Published online on: 11 July 2016

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Article Open Access

Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose

Zi-Ying Shen, Qian Sun, Zhong-Yuan Xia, Qing-Tao Meng, Shao-Qing Lei, Bo Zhao, Ling-Hua Tang, Rui Xue, Rong Chen
Pages: 729-736
Published online on: 14 July 2016

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Article Open Access

Knockdown of HMGN2 increases the internalization of Klebsiella pneumoniae by respiratory epithelial cells through the regulation of α5β1 integrin expression

Xinyuan Wang, Jingyu Li, Shanze Chen, Xiaofei Shen, Xiaolong Yang, Yan Teng, Luxia Deng, Yi Wang, Junli Chen, Xiaoying Wang, Ning Huang
Pages: 737-746
Published online on: 25 July 2016

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Article Open Access

Multi-glycoside of Tripterygium wilfordii Hook. f. ameliorates imiquimod-induced skin lesions through a STAT3-dependent mechanism involving the inhibition of Th17-mediated inflammatory responses

Jingxia Zhao, Tingting Di, Yan Wang, Xin Liu, Daiying Liang, Guangzhong Zhang, Ping Li
Pages: 747-757
Published online on: 11 July 2016

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Article Open Access

Sarcolemmal ATP-sensitive potassium channel protects cardiac myocytes against lipopolysaccharide-induced apoptosis

Xiaohui Zhang, Xiaohua Zhang, Yiqun Xiong, Chaoying Xu, Xinliang Liu, Jian Lin, Guiping Mu, Shaogang Xu, Wenhe Liu
Pages: 758-766
Published online on: 05 July 2016

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Article Open Access

The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats

Guofu Li, Jia Jia, Kaiqiang Ji, Xiaoying Gong, Rui Wang, Xiaoli Zhang, Haiyuan Wang, Bin Zang
Pages: 767-775
Published online on: 05 July 2016

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Article Open Access

Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family

Mohammed A. Suliman, Zhenxing Zhang, Heya Na, Ailton L.L. Ribeiro, Yu Zhang, Bachir Niang, Abdu Salim Hamid, Hua Zhang, Lijie Xu, Yunfei Zuo
Pages: 776-784
Published online on: 22 July 2016

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Article Open Access

TERT alleviates irradiation-induced late rectal injury by reducing hypoxia-induced ROS levels through the activation of NF-κB and autophagy

Qi Liu, Yong Sun, Yuefeng Lv, Ziyu Le, Yuhu Xin, Ping Zhang, Yong Liu
Pages: 785-793
Published online on: 11 July 2016

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Article Open Access

Effects of ghrelin on the apoptosis of human neutrophils in vitro

Bin Li, Mian Zeng, Haichong Zheng, Chunrong Huang, Wanmei He, Guifang Lu, Xia Li, Yanzhu Chen, Ruijie Xie
Pages: 794-802
Published online on: 06 July 2016

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Article Open Access

Ubiquitin-specific protease 4 inhibits breast cancer cell growth through the upregulation of PDCD4 Retraction in /10.3892/ijmm.2024.5417

Yang Li, Daqing Jiang, Qi Zhang, Xiaoli Liu, Zhengang Cai
Pages: 803-811
Published online on: 19 July 2016

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Article Open Access

Histone deacetylase inhibitors suppress RSV infection and alleviate virus-induced airway inflammation

Qiuqin Feng, Zhonglan Su, Shiyu Song, Hui Χu, Bin Zhang, Long Yi, Man Tian, Hongwei Wang
Pages: 812-822
Published online on: 26 July 2016

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Article Open Access

A potential target gene for the host-directed therapy of mycobacterial infection in murine macrophages

Zhang Bao, Ran Chen, Pei Zhang, Shan Lu, Xing Chen, Yake Yao, Xiaozheng Jin, Yilan Sun, Jianying Zhou
Pages: 823-833
Published online on: 11 July 2016

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Article

Picrasma quassiodes (D. Don) Benn. attenuates lipopolysaccharide (LPS)-induced acute lung injury

Jae-Won Lee, Ji-Won Park, Na-Rae Shin, So-Yeon Park, Ok-Kyoung Kwon, Hyun Ah Park, Yourim Lim, Hyung Won Ryu, Heung Joo Yuk, Jung Hee Kim, Sei-Ryang Oh, Kyung-Seop Ahn
Pages: 834-844
Published online on: 07 July 2016

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Article

miR-696 plays a role in hepatic gluconeogenesis in ob/ob mice by targeting PGC-1α

Zhijuan Fang, Peng Li, Wenhui Jia, Ting Jiang, Zhongyun Wang, Yang Xiang
Pages: 845-852
Published online on: 01 July 2016

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Article

Identification of NR0B1 as a novel androgen receptor co-repressor in mouse Sertoli cells

Yu-Chi Li, Man-Ling Luo, Huan Guo, Tian-Tian Wang, Shou-Ren Lin, Jian-Bo Chen, Qian Ma, Yan-Li Gu, Zhi-Mao Jiang, Yao-Ting Gui
Pages: 853-860
Published online on: 11 July 2016

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Article

Curcumin exerts antitumor effects in retinoblastoma cells by regulating the JNK and p38 MAPK pathways

Xiaoming Yu, Jingtao Zhong, Li Yan, Jie Li, Hui Wang, Yan Wen, Yu Zhao
Pages: 861-868
Published online on: 13 July 2016

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Article

Effects of caffeic acid on learning deficits in a model of Alzheimer's disease

Yunliang Wang, Yutong Wang, Jinfeng Li, Linlin Hua, Bing Han, Yuzhen Zhang, Xiaopeng Yang, Zhilei Zeng, Hongying Bai, Honglei Yin, Jiyu Lou
Pages: 869-875
Published online on: 18 July 2016

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Article

DEC2 is a negative regulator for the proliferation and differentiation of chondrocyte lineage-committed mesenchymal stem cells

Tomoko Sasamoto, Katsumi Fujimoto, Masami Kanawa, Junko Kimura, Junpei Takeuchi, Naoko Harada, Noriko Goto, Takeshi Kawamoto, Mitsuhide Noshiro, Ketut Suardita, Kazuo Tanne, Yukio Kato
Pages: 876-884
Published online on: 01 July 2016

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Article

Radioprotective 105 kDa protein attenuates ischemia/reperfusion-induced myocardial apoptosis and autophagy by inhibiting the activation of the TLR4/NF-κB signaling pathway in rats

Xin Guo, Hong Jiang, Jun Yang, Jing Chen, Jian Yang, Jia-Wang Ding, Song Li, Hui Wu, Hua-Sheng Ding
Pages: 885-893
Published online on: 19 July 2016

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Article

Transcriptomic changes in human renal proximal tubular cells revealed under hypoxic conditions by RNA sequencing

Wenmin Yu, Yiping Li, Zhi Wang, Lei Liu, Jing Liu, Fengan Ding, Xiaoyi Zhang, Zhengyuan Cheng, Pingsheng Chen, Jun Dou
Pages: 894-902
Published online on: 13 July 2016

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Article

Targeted blockade of JAK/STAT3 signaling inhibits proliferation, migration and collagen production as well as inducing the apoptosis of hepatic stellate cells

Yuan-Jing Gu, Wu-Yi Sun, Sen Zhang, Xin-Ran Li, Wei Wei
Pages: 903-911
Published online on: 26 July 2016

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Article

Benzyl isothiocyanate inhibits inflammasome activation in E. coli LPS-stimulated BV2 cells

Chang-Min Lee, Dae-Sung Lee, Won-Kyo Jung, Jong Su Yoo, Mi-Jin Yim, Yung Hyun Choi, Saegwang Park, Su-Kil Seo, Jung Sik Choi, Young-Min Lee, Won Sun Park, Il-Whan Choi
Pages: 912-918
Published online on: 06 July 2016

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Article

A single nucleotide polymorphism in the 3'-untranslated region of the KRAS gene disrupts the interaction with let-7a and enhances the metastatic potential of osteosarcoma cells

Shiqian Zhang, Chunying Hou, Guojun Li, Yang Zhong, Jie Zhang, Xinzhen Guo, Baoxin Li, Zhenggang Bi, Ming Shao
Pages: 919-926
Published online on: 04 July 2016

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Article

piR-651 promotes tumor formation in non-small cell lung carcinoma through the upregulation of cyclin D1 and CDK4

Dan Li, Yingquan Luo, Yawen Gao, Yue Yang, Yina Wang, Yan Xu, Shengyu Tan, Yuwei Zhang, Juan Duan, Yu Yang
Pages: 927-936
Published online on: 11 July 2016

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Article

Influence of cartilage interstitial fluid on the mRNA levels of matrix proteins, cytokines, metalloproteases and their inhibitors in synovial membrane

Anna Hyc, Stanislaw Moskalewski, Anna Osiecka-Iwan
Pages: 937-942
Published online on: 19 July 2016

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Article

Propofol protects hippocampal neurons from apoptosis in ischemic brain injury by increasing GLT-1 expression and inhibiting the activation of NMDAR via the JNK/Akt signaling pathway

Hong-Yan Gong, Fang Zheng, Chao Zhang, Xi-Yan Chen, Jing-Jing Liu, Xiu-Qin Yue
Pages: 943-950
Published online on: 05 July 2016

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Article

Development of a SYBR-Green Ⅰ quantitative PCR assay for the detection and genotyping of different hantaviruses

Ziyu Liu, Fang Wang, Lijuan Yuan, Xiaoxiao Zhang, Qikang Ying, Lan Yu, Liang Zhang, Linfeng Cheng, Fanglin Zhang, Jianguo Lu, Xing'an Wu
Pages: 951-960
Published online on: 13 July 2016

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Article

The peroxisome proliferator-activated receptor α agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes: Correlation with serum ALT levels

Petra Thulin, Krister Bamberg, Marcin Buler, Björn Dahl, Björn Glinghammar
Pages: 961-968
Published online on: 14 July 2016

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Article

Adenosine and the adenosine A2A receptor agonist, CGS21680, upregulate CD39 and CD73 expression through E2F-1 and CREB in regulatory T cells isolated from septic mice

Rui Bao, Xianqi Shui, Jiong Hou, Jinbao Li, Xiaoming Deng, Xiaoyan Zhu, Tao Yang
Pages: 969-975
Published online on: 14 July 2016

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Correction Open Access

[Corrigendum] Jumonji AT-rich interactive domain 1B overexpression is associated with the development and progression of glioma

Liping Fang, Jiuhan Zhao, Dan Wang, Liyu Zhu, Jian Wang, Kui Jiang
Pages: 976-976
Published online on: 15 July 2016

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Journal Cover
September-2026 Volume 58 Issue 3

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Mechanisms and therapeutic strategies of pyroptosis in sepsis‑induced acute lung injury (Review)

Wenyu Wu, Nuoran Li, Guoshu Deng, Suyi Yang, Ruifeng Zeng, Rui Chen, Jun Li
Article Number: 264
Published online on: 22 July 2026

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Review Open Access

Gut‑bone metabolites: SCFAs, polyamines and microbial metabolomics in osteoporosis risk and therapy (Review)

Fuchao Chen, Jingyue Sun, Xiao Wang
Article Number: 263
Published online on: 21 July 2026

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Expression of Concern Open Access

[Expression of Concern] Exposure to acoustic stimuli promotes the development and differentiation of neural stem cells from the cochlear nuclei through the clusterin pathway

Tao Xue, Li Wei, Ding-Jun Zha, Li Qiao, Lian-Jun Lu, Fu-Quan Chen, Jian-Hua Qiu
Article Number: 262
Published online on: 20 July 2026

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Article Open Access

Cepharanthine inhibits tick‑borne encephalitis virus infection through modulation of the stress and inflammation response

Wan-Da Tang, Lan-Juan Zhao
Article Number: 261
Published online on: 16 July 2026

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Article Open Access

circCACNA1D drives pulmonary fibrosis by regulating pyruvate kinase M2 dimer‑tetramer switching

Yujie Wang, Xiaoting Li, Meirong Wang, Nailiang Zhai, Mengqi Jiang, Bo Liu, Changjun Lv, Songzi Zhang, Xiaodong Song, Jinjin Zhang
Article Number: 260
Published online on: 15 July 2026

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Review Open Access

Recent progress and therapeutic strategies in the treatment of cervical neuroendocrine neoplasms (Review)

Yanpeng Tian, Yu Zhang, Liling Wang, Zhongkang Li, Xiaotong Xu, Shouze Liu, Shenyu Yang, Xiangyang Ren, Menghan Xu, Xingzi Chang, Xianghua Huang, Qian Zhao, Ruixia Guo
Article Number: 259
Published online on: 15 July 2026

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Review Open Access

Neurofibromin in bone disease: Mechanisms and therapeutic implications (Review)

Shuhong Zhang, Ge Yang
Article Number: 258
Published online on: 14 July 2026

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Review Open Access

Exercise‑induced exosomal noncoding RNAs: Molecular signaling cascades in bone remodeling and translational applications in sports‑related bone injuries (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 257
Published online on: 14 July 2026

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Review Open Access

Targeting alveolar type II cell dysfunction in idiopathic pulmonary fibrosis: Molecular mechanisms and emerging therapeutic strategies (Review)

Tianhao Xie, Kang Hu, Shu Pan, Xin Tong, Haitong Huang, Hao Ding, Jun Zhao
Article Number: 256
Published online on: 13 July 2026

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Article Open Access

Tubular PFKFB3 drives diabetic kidney fibrosis via lactate‑dependent H4K12 lactylation and HIPK2 transactivation

Mingkun Xu, Linhang Fu, Yulong Zhang, Xiuli Guo, Han Wu, Sijing Gao, Fei Xiao, Li Xu
Article Number: 255
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] p73 participates in WWOX-mediated apoptosis in leukemia cells

Donghong Lin, Zhaolei Cui, Lingying Kong, Feng Cheng, Jianping Xu, Fenghua Lan
Article Number: 254
Published online on: 13 July 2026

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Article Open Access

Role of hyperthermia in overcoming HPV‑mediated MHC‑Ⅰ downregulation and promoting immune surveillance

Hanyu Wang, Hongxin Lang, Yaoxing Guo, Te Sun, Yuansong Bai, Tao Zhang, Rui-Qun Qi
Article Number: 253
Published online on: 10 July 2026

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Review Open Access

Endocrine‑metabolic imbalance drives osteoarthritis: From whole‑joint pathobiology to precision therapy (Review)

Ruhui Yang, Haimin Zeng, Qi Xiao, Yining Xie, Yi Long, Xiang Chen
Article Number: 252
Published online on: 09 July 2026

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Expression of Concern Open Access

[Expression of Concern] Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells

Yumeng Shi, Dehua Zhou, Bingyi Wang, Deren Zhou, Baomin Shi
Article Number: 251
Published online on: 08 July 2026

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Article Open Access

Phenylalanine exacerbates psoriasiform inflammation through NF‑κB‑mediated dendritic cell activation and Th17 polarization

Yaohan Xu, Jing Pan, Jie Chen, Yutao Zhu, Miaolian Cai, Zeyu Ma, Siji Chen, Tianze Yu, Yushu Wei, Jingying Pan, Kunliang Luo, Yinjing Song, Stijn Van Der Veen, Hao Cheng
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

Protective effects of Astragaloside IV on various liver diseases: From chemistry to herbal medicines (Review)

Jialu Shi, Xiaoyu Zhou, Jiabin Wu, Liru Zeng, Xia Wang, Wei Li, Xiao Huang, Xiaoyu Deng, Wenhong Wang
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

GRP78 dysregulation: A proposed molecular mechanism linking the tumor microenvironment to sepsis susceptibility in patients with cancer (Review)

Hang Ruan, Meipeng Zhu, Shi-Yan Liu, Li-Juan Zou, Shu-Sheng Li
Article Number: 248
Published online on: 07 July 2026

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Review Open Access

FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review)

Changzhong Qian, Zhenyu Zhang, Xian Wu, Huibo Ti, Junjie Wu, Zhengdong Yuan, Xia Li, Feng-Lai Yuan
Article Number: 247
Published online on: 06 July 2026

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Retraction Open Access

[Retracted] β‑catenin signaling induces the osteoblastogenic differentiation of human pre‑osteoblastic and bone marrow stromal cells mainly through the upregulation of osterix expression

Bo Liu, Song Wu, Lihua Han, Chaoyue Zhang
Article Number: 246
Published online on: 06 July 2026

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Article Open Access

Single‑cell atlas reveals a Wilms' tumor 1‑mediated axis driving granulosa cell senescence in human ovarian aging

Yanfang Du, Congyu Zhou, Yanpeng Tian, Zhongkang Li, Xianghua Huang
Article Number: 245
Published online on: 03 July 2026

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Review Open Access

TRPV1‑mediated central sensitisation: Core mechanisms of migraine chronification and novel targeted therapeutic strategies (Review)

Mingxia Zhang, Yuting Pu, Yujie Zhang, Jia Hu, Shuangyang Li, Hongmei Tang, Bangjiang Fang, Xue Bai
Article Number: 244
Published online on: 02 July 2026

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Correction Open Access

[Corrigendum] Arginine ADP‑ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway

Lian Yang, Ming Xiao, Xian Li, Yi Tang, Ya-Lan Wang
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

Research progress on the chemical and pharmacological effects of Semen Strychni (Review)

Jingxin Mao, Xin Du, Dan Zeng, Xin Luo, Yan Li
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

FLI1 enhances the malignant phenotype of glioma cells and exerts immunomodulatory effects through feedback crosstalk with exonic circRNA FECR1 and interferon‑induced ISG15

Xue Wen, Xiaoyi Gu, Xu Yan, Naifei Chen, Lei Zhou, Hui Li, Andrew R. Hoffman, Wei Li, Ji-Fan Hu, Jiuwei Cui
Article Number: 241
Published online on: 01 July 2026

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Review Open Access

Role of ZEB1 in angiogenesis and therapeutic potential (Review)

Ruoxin Ren, Chunxiao Yan, Yao Xiang, Lin Jin, Fang Cheng, Lijun Zhang
Article Number: 240
Published online on: 01 July 2026

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Review Open Access

Endothelial dysfunction: A central mechanism linking autosomal dominant polycystic kidney disease and intracranial aneurysms (Review)

Xiaohong Xu, Ruyi Xu, Liexiang Zhang
Article Number: 239
Published online on: 01 July 2026

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Correction Open Access

[Corrigendum] Effect of SDF‑1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury

Jun Li, Weichun Guo, Min Xiong, Heng Han, Jie Chen, Dan Mao, Bing Tang, Hualong Yu, Yun Zeng
Article Number: 238
Published online on: 01 July 2026

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Review Open Access

Exercise and fluoxetine in Alzheimer's disease: Molecular mechanisms of synergistic and antagonistic effects (Review)

Mei Wu, Yan Li
Article Number: 237
Published online on: 30 June 2026

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Review Open Access

Oral‑gut axis in systemic disease: A barrier‑metabolism‑immunity three‑dimensional regulatory model (Review)

Qing Li, Mingrong Cheng, Weiwei Li, Xiaoyue Wang, Xiaoqing Liu, Yujie Yan
Article Number: 236
Published online on: 30 June 2026

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Review Open Access

ABCG2 transporter: Structural and functional associations with gout (Review)

Muhammad Arslan Asif, Zeshan Zulfiqar, Bahar E. Mustafa, Usman Nazir, Jiamen Sun, Zhichang Wang, Yalei Cui, Sun Hao, Liu Boshuai, Yinghua Shi
Article Number: 235
Published online on: 30 June 2026

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Review Open Access

Neuropilin‑1: Emerging roles in nerve‑vessel‑bone coupling during fracture repair (Review)

Keyue Zhang, Tong Li, Huan Liu, Huibo Ti, Zhenyu Zhang, Zhengdong Yuan, Junjie Wu, Xielin Yan, Zixin Luo, Haiting Hu, Xingchen Yao, Shuwen Shi, Xian Wu, Feng-Lai Yuan, Xiao Chen
Article Number: 234
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] Crocin exerts anti‑inflammatory and anti‑catabolic effects on rat intervertebral discs by suppressing the activation of JNK

Kang Li, Yan Li, Zhenjiang Ma, Jie Zhao
Article Number: 233
Published online on: 29 June 2026

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Review Open Access

Skeletal muscle‑derived extracellular vesicles in multi‑organ degenerative disease: Mechanisms and therapeutic delivery perspectives (Review)

Xianji Wei, Chengyan Guo, Wei Zhang, Guanyi Wang, Wenjing Li, Binghong Gao, Bo Gao, Lingli Zhang
Article Number: 232
Published online on: 26 June 2026

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October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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