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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2019 Volume 44 Issue 3

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

RIP1/RIP3-regulated necroptosis as a target for multifaceted disease therapy (Review)

Yuping Liu, Ting Liu, Tiantian Lei, Dingding Zhang, Suya Du, Lea Girani, Dandan Qi, Chen Lin, Rongsheng Tong, Yi Wang
Pages: 771-786
Published online on: 14 June 2019

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Article Open Access

Construction of prognostic risk prediction model of oral squamous cell carcinoma based on co-methylated genes

Qiang Zhu , Gang Tian, Jianyong Gao
Pages: 787-796
Published online on: 13 June 2019

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Article Open Access

Epigenetic regulation of COX‑2 expression by DNA hypomethylation via NF‑κB activation in ketamine‑induced ulcerative cystitis

Shu‑Mien Chuang, Jian‑He Lu, Kun‑Ling Lin, Cheng‑Yu Long, Yung‑Chin Lee, Hui‑Pin Hsiao, Chia‑Chun Tsai, Wen‑Jeng Wu, Hui‑Jun Yang, Yung‑Shun Juan
Pages: 797-812
Published online on: 21 June 2019

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Article Open Access

Effect of HMGB1 and RAGE on brain injury and the protective mechanism of glycyrrhizin in intracranial‑sinus occlusion followed by mechanical thrombectomy recanalization

Shu‑Wen Mu, Yuan Dang, Ya‑Cao Fan, Hao Zhang, Jian‑He Zhang, Wei Wang, Shou‑Sen Wang, Jian‑Jun Gu
Pages: 813-822
Published online on: 20 June 2019

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Article Open Access

Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS

Mingyue Liu, Haibin Mu, Wenting Peng, Lin Zhao, Weiping Hu, Zhuling Jiang, Li Gao, Xiaofang Cao, Ning Li, Jingying Han
Pages: 823-834
Published online on: 18 June 2019

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Article Open Access

Altered expression of itch‑related mediators in the lower cervical spinal cord in mouse models of two types of chronic itch

Bao‑Wen Liu, Zhi‑Xiao Li, Zhi‑Gang He, Qian Wang, Cheng Liu, Xian‑Wei Zhang, Hui Yang, Hong‑Bing Xiang
Pages: 835-846
Published online on: 24 June 2019

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Article Open Access

Astragaloside IV inhibits oxidized low‑density lipoprotein‑induced endothelial damage via upregulation of miR‑140‑3p Retraction in /10.3892/ijmm.2023.5220

Weibin Qian, Qiuhai Qian, Xinrui Cai, Ru Han, Wenjun Yang, Xinyue Zhang, Hongmin Zhao, Ranran Zhu
Pages: 847-856
Published online on: 26 June 2019

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Article Open Access

The role of antimiR-26a-5p/biphasic calcium phosphate in repairing rat femoral defects

Xiaoyan Yuan, Lu Han, Hai Lin, Zeyou Guo, Yanling Huang, Shasha Li, Ting Long, Wei Tang, Weidong Tian, Jie Long
Pages: 857-870
Published online on: 20 June 2019

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Article Open Access

Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension

Dapeng Wang, Hongyang Xu, Bo Wu, Shuyun Jiang, Hong Pan, Ruilan Wang, Jingyu Chen
Pages: 871-884
Published online on: 25 June 2019

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Article Open Access

HMGB1 enhances mechanical stress-induced cardiomyocyte hypertrophy in vitro via the RAGE/ERK1/2 signaling pathway

Lei Zhang, Xue Yang, Guoliang Jiang, Ying Yu, Jian Wu, Yangang Su, Aijun Sun, Yunzeng Zou, Hong Jiang, Junbo Ge
Pages: 885-892
Published online on: 16 July 2019

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Article Open Access

Quercetin protects against atherosclerosis by regulating the expression of PCSK9, CD36, PPARγ, LXRα and ABCA1

Qingling Jia, Hui Cao, Dingzhu Shen, Shanshan Li, Li Yan, Chuan Chen, Sanli Xing, Fangfang Dou
Pages: 893-902
Published online on: 03 July 2019

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Article Open Access

Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis Retraction in /10.3892/ijmm.2026.5730

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Pages: 903-912
Published online on: 05 July 2019

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Article Open Access

Leonurus sibiricus L. ethanol extract promotes osteoblast differentiation and inhibits osteoclast formation

Jae‑Hyun Kim, Minsun Kim, Hyuk‑Sang Jung, Youngjoo Sohn
Pages: 913-926
Published online on: 08 July 2019

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Article Open Access

Effects of high glucose on proliferation and function of circulating fibrocytes: Involvement of CXCR4/SDF‑1 axis

Yingzheng Weng, Jiangjie Lou, Xiaowei Liu, Senna Lin, Chenkai Xu, Changqing Du, Lijiang Tang
Pages: 927-938
Published online on: 27 June 2019

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Article Open Access

Expression changes of CX3CL1 and CX3CR1 proteins in the hippocampal CA1 field of the gerbil following transient global cerebral ischemia

Ji Hyeon Ahn, Dae Won Kim, Joon Ha Park, Tae‑Kyeong Lee, Hyang‑Ah Lee, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 939-948
Published online on: 10 July 2019

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Article Open Access

Pistacia weinmannifolia ameliorates cigarette smoke and lipopolysaccharide‑induced pulmonary inflammation by inhibiting interleukin‑8 production and NF‑κB activation

Jae‑Won Lee, Hyung Won Ryu, Su Ui Lee, Min‑Gu Kim, Ok‑Kyoung Kwon, Mun Ok Kim, Tae Kyu Oh, Jae Kyoung Lee, Tae Young Kim, Sang Woo Lee, Sangho Choi, Wan‑Yi Li, Kyung‑Seop Ahn, Sei‑Ryang Oh
Pages: 949-959
Published online on: 20 June 2019

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Article Open Access

Micro‑dimpled surface atelocollagen maintains primary human hepatocytes in culture and may promote their functionality compared with collagen coat culture

Tetsuro Sato, Kayoko Semura, Ichiro Fujimoto
Pages: 960-972
Published online on: 21 June 2019

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Article Open Access

miR-92a-3p promotes the proliferation, migration and invasion of esophageal squamous cell cancer by regulating PTEN Retraction in /10.3892/ijmm.2024.5453

Xin Li, Shuilong Guo, Li Min, Qingdong Guo, Shutian Zhang
Pages: 973-981
Published online on: 27 June 2019

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Article Open Access

Gas6 attenuates lipopolysaccharide‑induced TNF‑α expression and apoptosis in H9C2 cells through NF‑κB and MAPK inhibition via the Axl/PI3K/Akt pathway

Mengfang Li, Jingjing Ye, Guangju Zhao, Guangliang Hong, Xiyi Hu, Kaiqiang Cao, You Wu, Zhongqiu Lu
Pages: 982-994
Published online on: 12 July 2019

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Article Open Access

SIRT1 activation alleviates brain microvascular endothelial dysfunction in peroxisomal disorders

Yunshan Zhang, Guiyun Cui, Yue Wang, Yi Gong, Yulan Wang
Pages: 995-1005
Published online on: 20 June 2019

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Article Open Access

Comparison of the therapeutic effects of adipose‑derived and bone marrow mesenchymal stem cells on erectile dysfunction in diabetic rats

Sansan Chen, Jianbin Zhu, Mingzhu Wang, Yanting Huang, Zhuolin Qiu, Jingjing Li, Xinglu Chen, Huiying Chen, Mingyu Xu, Jun Liu, Miaoqin She, Hongwei Li, Xiaorong Yang, Yi Wang, Xiangsheng Cai
Pages: 1006-1014
Published online on: 24 June 2019

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Article Open Access

Identification of long non‑coding RNA‑mediated transcriptional dysregulation triplets reveals global patterns and prognostic biomarkers for ER+/PR+, HER2‑ and triple negative breast cancer

Zhengwei Du, Wei Gao, Jiayi Sun, Yujing Li, Yu Sun, Tong Chen, Shuke Ge, Wenbin Guo
Pages: 1015-1025
Published online on: 27 June 2019

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Article Open Access

Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway

Jiquan Wang, Yingbing Zhang, Xu Liu, Jizhao Wang, Bin Li, Yongkang Liu, Jiansheng Wang
Pages: 1026-1038
Published online on: 08 July 2019

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Article Open Access

Downregulated miR‑302d‑3p promotes chondrocyte proliferation and migration by regulation of Unc‑51‑like kinase 1

Shangzeng Wang, Yongzhi Zheng, Zheng Hu, Zhen Wang, Yingjie Zhang, Licheng Wei
Pages: 1039-1047
Published online on: 05 July 2019

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Article Open Access

Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy

Li Yao, Hongguang Chen, Qinghua Wu, Keliang Xie
Pages: 1048-1062
Published online on: 03 July 2019

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Article Open Access

Circular RNA profile in liver tissue of EpCAM knockout mice

Yanhong Yang, Shaomin Liu, Zili Lei, Guibin Chen, Li Huang, Fei Yang, Yuting Lei, Yanyan Liu, Lanxiang Yang, Wanwan Liu, Liangxue Lai, Jiao Guo
Pages: 1063-1077
Published online on: 08 July 2019

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Article Open Access

Hypertonic saline downregulates endothelial cell-derived VEGF expression and reduces blood-brain barrier permeability induced by cerebral ischaemia via the VEGFR2/eNOS pathway

Qiaosheng Wang, Yiyu Deng, Linqiang Huang, Wenxin Zeng, Shenglong Chen, Bo Lv, Wenqiang Jiang, Yongli Han, Hongguang Ding, Miaoyun Wen, Hongke Zeng
Pages: 1078-1090
Published online on: 02 July 2019

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Article Open Access

Increased expression of Sonic hedgehog restores diabetic endothelial progenitor cells and improves cardiac repair after acute myocardial infarction in diabetic mice

Qing Xiao, Xiao‑Ya Zhao, Ru‑Chao Jiang, Xiu‑Hui Chen, Xiang Zhu, Kai‑Feng Chen, Sheng‑Ying Chen, Xiao‑Ling Zhang, Yuan Qin, Ying‑Hua Liu, Jian‑Dong Luo
Pages: 1091-1105
Published online on: 16 July 2019

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Article

Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis

Yan Sun, Wensheng Pan, Jun Zhang, Ying Cui, Huiju Wang, Guoqing Ru, Legao Chen
Pages: 1106-1116
Published online on: 08 July 2019

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Article

CaSR activates PKCδ to induce cardiomyocyte apoptosis via ER stress‑associated apoptotic pathways during ischemia/reperfusion

Chong Liu, Huanming Li, Huishuang Zheng, Meili Zhai, Fanghao Lu, Shiyun Dong, Tao Fang, Weihua Zhang
Pages: 1117-1126
Published online on: 24 June 2019

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Article

Alcohol‑induced attenuation of post‑traumatic inflammation is not necessarily liver‑protective following trauma/hemorrhage

Nils Wagner, Scott Dieteren, Niklas Franz, Kernt Köhler, Mario Perl, Ingo Marzi, Borna Relja
Pages: 1127-1138
Published online on: 27 June 2019

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Article

Downregulation of microRNA‑629‑5p in colorectal cancer and prevention of the malignant phenotype by direct targeting of low‑density lipoprotein receptor‑related protein 6 Retraction in /10.3892/ijmm.2021.5057

Guoqiang Yan, Chenyao Li, Yuhang Zhao, Meng Yue, Lei Wang
Pages: 1139-1150
Published online on: 18 June 2019

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Article

Biologically active 1,25-dihydroxyvitamin D3 protects against experimental sepsis by negatively regulating the Toll-like receptor 4/myeloid differentiation primary response gene 88/Toll-IL-1 resistance-domain-containing adapter-inducing interferon-β signaling pathway

Ge Zheng, Na Wen, Minli Pan, Yumao Huang, Zhishu Li
Pages: 1151-1160
Published online on: 05 July 2019

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Article

GLP‑1 improves palmitate‑induced insulin resistance in human skeletal muscle via SIRT1 activity

Ja Young Jeon, Sung‑E Choi, Eun Suk Ha, Han Byeol Lee, Tae Ho Kim, Seung Jin Han, Hae Jin Kim, Dae Jung Kim, Yup Kang, Kwan‑Woo Lee
Pages: 1161-1171
Published online on: 09 July 2019

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Article

MicroRNA-592 suppresses the malignant phenotypes of thyroid cancer by regulating lncRNA NEAT1 and downregulating NOVA1

Yiqiang Luo, Tianwei Hao, Jian Zhang, Ming Zhang, Peng Sun, Lei Wu
Pages: 1172-1182
Published online on: 16 July 2019

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Correction Open Access

[Corrigendum] Alterations in gene expression during sexual differentiation in androgen receptor knockout mice induced by environmental endocrine disruptors

Dehong Liu, Liping Shen, Yonglin Tao, Ying Kuang, Lei Cai, Dan Wang, Meiduo He, Xuebo Tong, Shuguang Zhou, Jie Sun, Chenchen Shi, Chunxiao Wang, Yi Wu
Pages: 1183-1183
Published online on: 11 July 2019

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Spatial multi‑omics identifies an SPP1+ macrophage‑driven anti‑apoptotic niche in osteoarthritis synovium via the SPP1‑CD44 axis

Han Gong, Hao Shen, Feng Zhang, Wei Wang, Sheng Zhou, Lei Wang, Yu Sun
Article Number: 334
Published online on: 29 September 2026

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Review Open Access

Novel insights into the role of the renal interstitial microenvironment in Randall's plaque formation (Review)

Jialiang Wang, Zhangcheng Liao, Minghui Liu, Yizhou Wang, Yu Cui, Hequn Chen, Feng Zeng, Zewu Zhu
Article Number: 333
Published online on: 29 September 2026

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Correction Open Access

[Corrigendum] Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model

Jingfei Chen, Zhimin Long, Yanzhen Li, Min  Luo, Shifang  Luo, Guiqiong He
Article Number: 332
Published online on: 28 September 2026

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Article Open Access

miR‑222‑3p inhibits diabetic skin wound healing by targeting APLN

Ruyan Jie, Ying Tang, Tingting Wu, Chenfan Zhang, Man Song, Xiaotong Zhao, Mingwei Chen
Article Number: 331
Published online on: 25 September 2026

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Correction Open Access

[Corrigendum] Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production

Keyi Geng, Ningzhen Fu, Xiao Yang, Weiliang Xia
Article Number: 330
Published online on: 23 September 2026

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Article Open Access

Salidroside attenuates myocardial ischemia‑reperfusion‑induced oxidative stress and ferroptosis by promoting USP11‑mediated  deubiquitination of PRDX2

Zhi-Cong Qiu, Jian-Nan Li, Yi-Zhou Li, Zi-Ming Wu, Xu-Dong Luo, Rui-Yuan Zeng, Song-Qing Lai, Shi-Tao Zhao, Li Wan
Article Number: 329
Published online on: 23 September 2026

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Review Open Access

Reprogramming of cell death in gastric cancer: From molecular mechanisms to therapeutic potential (Review)

Mengru Liu, Zhujun Wu, Qiao Chen, Weiguo Ni, Ying Chen, Yixin Zhu, Yu Chen, Haifeng Ma, Yan Lin
Article Number: 328
Published online on: 23 September 2026

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Article Open Access

Remimazolam attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis involving the AKT/SLC7A11/GPX4 axis

Xiyuan Chen, Jianghong Zhao, Xingtong He, Yuqi Zhang, Jiao Wu, Chao Jiang, Yi Yang, Ji Xiao
Article Number: 327
Published online on: 22 September 2026

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Review Open Access

Tumor‑immune spatiotemporal co‑evolution: A new paradigm for understanding and overcoming therapy resistance in metastatic castration‑resistant prostate cancer (Review)

Li Yan, Xiaoke Sun, Pengxiao Su
Article Number: 326
Published online on: 21 September 2026

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Review Open Access

Research progress on the role of IL‑37 in gynecological and obstetrics‑related diseases (Review)

Hongjing Wang, Renukha Arjune, Weiyu Gan, Na Guo, Nan Yu, Ting Xiong
Article Number: 325
Published online on: 21 September 2026

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Expression of Concern Open Access

[Expression of Concern] PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids

Elena Grasselli, Adriana Voci, Carlo Pesce, Laura Canesi, Emilia Fugassa, Gabriella Gallo, Laura Vergani
Article Number: 324
Published online on: 21 September 2026

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Review Open Access

Neutrophil extracellular traps in cardiovascular disease: Mechanisms and therapeutic implications (Review)

Zhao Wang, Mingde Chang, Wenyu Shang, Yunfeng Jia, Xiaoyu Shan, Xinnong Chen, Yingxi Yang, Junping Zhang
Article Number: 323
Published online on: 18 September 2026

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Article Open Access

Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis

Fei Yan, Lei Shi, Yuechan Wang, Ying Zhao, Yuanyuan Wu, Dubiao Xian, Yunheng Liang, Ning Wang, Hongwang Cui, Minni Zhang
Article Number: 322
Published online on: 18 September 2026

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Article Open Access

Ketogenic diet attenuates Müller cell activation and retinal neuroinflammation in autoimmune glaucoma through acetylation‑mediated FOXO signalling

Sisi Tan, Xiaochen Wang, Yunfan Zheng, Zhenni Mou, Lihong Zeng, Jingchang Yuan, Xiao Fan, Miao Wei, Yujia Huo, Ruotong Ouyang, Yanyu Pu, Junqin Lei, Xi Gao, Dangdang Wang, Yang Peng, Hong Li
Article Number: 321
Published online on: 17 September 2026

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Review Open Access

ILC3s as central regulators of mucosal homeostasis and disease pathogenesis (Review)

Jingwen Zhang, Lili Bao, Jiaxi Li, Xia Li, Lu Qiao, Jiaxian Cui, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Yaoqing Feng, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 320
Published online on: 17 September 2026

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Review Open Access

Small extracellular vesicles in osteoarthritis: A double‑edged sword regulating inflammation and cartilage homeostasis (Review)

Yifan Yang, Jiachen Liang, Xiangyu Shi, Anqi Niu, Ruifang Gao, Xiuping Wu, Xiaojuan Guo, Xiaotong Shi, Kejie Cao, Bing Li, Ran Li
Article Number: 319
Published online on: 17 September 2026

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Review Open Access

Exosomal circular RNAs in the tumor immune microenvironment: From regulatory mechanisms to therapeutic opportunities and translational hurdles (Review)

Wenlong Zhang, Nuo Chen, Liya Gong, Yu Dong, Hui Shen, Xin Liu, Jie Sun, Luxuan Liu, Zhe Jin, Liaoyuan Wang, Xue Han, Bin Zhang, Shuixing Zhang
Article Number: 318
Published online on: 17 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Tan-Zhen Xu, Xiao-Yan Shen, Ling-Ling Sun, Ya-Li Chen, Bi-Qiong Zhang, Da-Ke Huang, Wei-Zu Li
Article Number: 317
Published online on: 16 September 2026

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Review Open Access

tRNA‑derived RNAs in hepatic diseases: From biological functions to clinical translation (Review)

Yaotian Cai, Yifei Chen, Fuji Yang, Yongmin Yan, Ting Jiang
Article Number: 316
Published online on: 15 September 2026

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Monocytes in pneumonia: Functional plasticity and innate memory (Review) 

Run-Ze Li, Zhi-Han Xie, Li Chen, Yun-Xiao Shang, Fei Wang, Wan-Jie Huang, Qi Cheng
Article Number: 315
Published online on: 15 September 2026

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Correction Open Access

[Corrigendum] Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 314
Published online on: 14 September 2026

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Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review)

Hongguang Gao, Yang Chen, Tianshan Zhang, Yujun Shi, Rong Yao
Article Number: 313
Published online on: 10 September 2026

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Correction Open Access

[Corrigendum] Inactivation of von Hippel‑Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR‑210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Article Number: 312
Published online on: 10 September 2026

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Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Immune remodeling in inflammatory bowel disease-associated colorectal cancer: Mechanisms and immunotherapeutic implications (Review)

Tao Zhang, Zhetan Ren, Ling Wang, Ru Man, Lin Wang, Jing Wang, Xiaozhen Cheng, Jirun Peng, Yongduo Yu
Article Number: 353
Published online on: 22 October 2026

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Inflammatory regulatory mechanisms and targeted therapy of antineutrophil cytoplasmic antibodies in atherosclerosis (Review)

Jingjing Cui, Qi Cui, Jinying Dou, Xiaoyan Li, Wenlong Chang, Lanchun Shi, Liyun An
Article Number: 352
Published online on: 22 October 2026

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HMGN5 promotes renal tubular inflammation and pyroptosis‑associated signaling in chronic kidney disease via the IFNAR2 axis

Xue Rong, Jing Xu, Jienan Zhang, Qi Zhang, Jiangli Wang, Guoxin Zhang, Limin Nie
Article Number: 351
Published online on: 22 October 2026

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[Corrigendum] Radiation induces primary osteocyte senescence phenotype and affects osteoclastogenesis in vitro

Yuyang Wang, Linshan Xu, Jianping Wang, Jiangtao Bai, Jianglong Zhai, Guoying Zhu
Article Number: 350
Published online on: 21 October 2026

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Transcription factors in liver fibrosis: Mechanistic insights and nanotechnology‑driven therapeutic strategies (Review)

Xianfei Zhou, Chongjun Yang, Zhiyong Weng, Lihua Li
Article Number: 349
Published online on: 21 October 2026

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From RNA fate to cancer state transitions: m5C‑driven metabolic and immune reprogramming (Review)

Yuanli Zhou, Bolv Zhu, Xingzhou Tang, Shuishui Yin
Article Number: 348
Published online on: 20 October 2026

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[Corrigendum] Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis 

Dong Ding, Jiangbo Yan, Gangning Feng, Yong Zhou, Long Ma, Qunhua Jin
Article Number: 347
Published online on: 19 October 2026

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Centrosomal protein 55: Research progress on biological characteristics, disease associations and clinical translational potential (Review)

Sanmei Nong, Qiudong Huang, Kuibo Huang, Xiao Luo, Yin Huang, Wenlian Zheng, Weiyi Huang, Zhaoyun Liu
Article Number: 346
Published online on: 16 October 2026

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Multiple strategies to improve the therapeutic efficacy of mesenchymal stem cell‑derived exosome transplantation in ischemic stroke (Review)

Yan Xu, Xiaolei Zhou, Wenhui Zeng, Jiabing Wang, Lin Zhou, Lincai Li, Zhengwei Zou, Cixiang Chen, Yichi Zhang, Zhengyi He, Junsong Ye
Article Number: 345
Published online on: 14 October 2026

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Resveratrol alleviates osteoarthritis progression by inhibiting NLRP3 inflammasome response via the AMPK/PPARγ signaling pathway

Shanshan Cui, Zifan Luo, Wen Qin, Bo Chen, Qiaoxia Zhang, Jianbing Ma, Jie Ma, Rui Zhang
Article Number: 344
Published online on: 14 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic and differential effects on protein expression of epigallocatechin‑3‑gallate in HCCLM6 hepatocellular carcinoma cells

Yunjuan Zhang, Lawrence Owusu, Wei Duan, Tao Jiang, Shizhu Zang, Ayaz Ahmed, Yi Xin
Article Number: 343
Published online on: 14 October 2026

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Article Open Access

Six3 promoting the migration and neural differentiation of BMSCs via Btg2‑mediated Akt signaling pathway activation: A therapeutic strategy for stroke

Zhenqiang Fu, Zhixin Li, Limin Zhang, Wentao Hu, Hecheng Yang, Jingtao Wang
Article Number: 342
Published online on: 12 October 2026

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Expression of Concern Open Access

[Expression of Concern] EETs and CYP2J2 inhibit TNF‑α‑induced apoptosis in pulmonary artery endothelial cells and TGF‑β1‑induced migration in pulmonary artery smooth muscle cells

Wenjing Feng, Xizhen Xu, Gang Zhao, Geng Li, Tiantian Liu, Junjie Zhao, Ruolan Dong, Dao Wen Wang, Ling Tu
Article Number: 341
Published online on: 12 October 2026

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Gomisin A as a multi‑target therapeutic agent: Pharmacological mechanisms, pharmacokinetics and network pharmacology (Review)

Jiaqi Xu, Sha Shi, Chengkai Zhu, Qi Sui, Shanhao Zhu, Jingnan Zhang, Yi Zhang, Peng Chen
Article Number: 340
Published online on: 09 October 2026

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Multi‑target mechanisms of paeoniflorin in inflammatory regulation: A network pharmacology (Review)

Jin Zhang, Junjie Ye, Kun Jin, Xuan Sun, Xinyu Yu, Yuan Zhao, Ni Zhu
Article Number: 339
Published online on: 09 October 2026

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Mechanisms of neuroimmune crosstalk in vestibular disorders: Linking inflammation with neural circuit dysfunction (Review)

Xianfang Pan, Jin Fan, Zhiyi Yang, Zegang Yin, Zhen Li, Zhifeng Rui, Hujun Zhang, Yujie Li, Hongjuan Zhang
Article Number: 338
Published online on: 08 October 2026

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Expression of Concern Open Access

[Expression of Concern] Gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP‑1

Zeng-Feng Xin, Cheng-Chun Shen, Li-Jiang Tao, Shi-Gui Yan, Hao-Bo Wu
Article Number: 337
Published online on: 08 October 2026

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Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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