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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2019 Volume 44 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

RIP1/RIP3-regulated necroptosis as a target for multifaceted disease therapy (Review)

Yuping Liu, Ting Liu, Tiantian Lei, Dingding Zhang, Suya Du, Lea Girani, Dandan Qi, Chen Lin, Rongsheng Tong, Yi Wang
Pages: 771-786
Published online on: 14 June 2019

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Article Open Access

Construction of prognostic risk prediction model of oral squamous cell carcinoma based on co-methylated genes

Qiang Zhu , Gang Tian, Jianyong Gao
Pages: 787-796
Published online on: 13 June 2019

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Article Open Access

Epigenetic regulation of COX‑2 expression by DNA hypomethylation via NF‑κB activation in ketamine‑induced ulcerative cystitis

Shu‑Mien Chuang, Jian‑He Lu, Kun‑Ling Lin, Cheng‑Yu Long, Yung‑Chin Lee, Hui‑Pin Hsiao, Chia‑Chun Tsai, Wen‑Jeng Wu, Hui‑Jun Yang, Yung‑Shun Juan
Pages: 797-812
Published online on: 21 June 2019

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Article Open Access

Effect of HMGB1 and RAGE on brain injury and the protective mechanism of glycyrrhizin in intracranial‑sinus occlusion followed by mechanical thrombectomy recanalization

Shu‑Wen Mu, Yuan Dang, Ya‑Cao Fan, Hao Zhang, Jian‑He Zhang, Wei Wang, Shou‑Sen Wang, Jian‑Jun Gu
Pages: 813-822
Published online on: 20 June 2019

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Article Open Access

Time-dependent C5a and C5aR expression in dental pulp cells following stimulation with LTA and LPS

Mingyue Liu, Haibin Mu, Wenting Peng, Lin Zhao, Weiping Hu, Zhuling Jiang, Li Gao, Xiaofang Cao, Ning Li, Jingying Han
Pages: 823-834
Published online on: 18 June 2019

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Article Open Access

Altered expression of itch‑related mediators in the lower cervical spinal cord in mouse models of two types of chronic itch

Bao‑Wen Liu, Zhi‑Xiao Li, Zhi‑Gang He, Qian Wang, Cheng Liu, Xian‑Wei Zhang, Hui Yang, Hong‑Bing Xiang
Pages: 835-846
Published online on: 24 June 2019

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Article Open Access

Astragaloside IV inhibits oxidized low‑density lipoprotein‑induced endothelial damage via upregulation of miR‑140‑3p Retraction in /10.3892/ijmm.2023.5220

Weibin Qian, Qiuhai Qian, Xinrui Cai, Ru Han, Wenjun Yang, Xinyue Zhang, Hongmin Zhao, Ranran Zhu
Pages: 847-856
Published online on: 26 June 2019

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Article Open Access

The role of antimiR-26a-5p/biphasic calcium phosphate in repairing rat femoral defects

Xiaoyan Yuan, Lu Han, Hai Lin, Zeyou Guo, Yanling Huang, Shasha Li, Ting Long, Wei Tang, Weidong Tian, Jie Long
Pages: 857-870
Published online on: 20 June 2019

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Article Open Access

Long non‑coding RNA MALAT1 sponges miR‑124‑3p.1/KLF5 to promote pulmonary vascular remodeling and cell cycle progression of pulmonary artery hypertension

Dapeng Wang, Hongyang Xu, Bo Wu, Shuyun Jiang, Hong Pan, Ruilan Wang, Jingyu Chen
Pages: 871-884
Published online on: 25 June 2019

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Article Open Access

HMGB1 enhances mechanical stress-induced cardiomyocyte hypertrophy in vitro via the RAGE/ERK1/2 signaling pathway

Lei Zhang, Xue Yang, Guoliang Jiang, Ying Yu, Jian Wu, Yangang Su, Aijun Sun, Yunzeng Zou, Hong Jiang, Junbo Ge
Pages: 885-892
Published online on: 16 July 2019

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Article Open Access

Quercetin protects against atherosclerosis by regulating the expression of PCSK9, CD36, PPARγ, LXRα and ABCA1

Qingling Jia, Hui Cao, Dingzhu Shen, Shanshan Li, Li Yan, Chuan Chen, Sanli Xing, Fangfang Dou
Pages: 893-902
Published online on: 03 July 2019

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Article Open Access

Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis Retraction in /10.3892/ijmm.2026.5730

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Pages: 903-912
Published online on: 05 July 2019

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Article Open Access

Leonurus sibiricus L. ethanol extract promotes osteoblast differentiation and inhibits osteoclast formation

Jae‑Hyun Kim, Minsun Kim, Hyuk‑Sang Jung, Youngjoo Sohn
Pages: 913-926
Published online on: 08 July 2019

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Article Open Access

Effects of high glucose on proliferation and function of circulating fibrocytes: Involvement of CXCR4/SDF‑1 axis

Yingzheng Weng, Jiangjie Lou, Xiaowei Liu, Senna Lin, Chenkai Xu, Changqing Du, Lijiang Tang
Pages: 927-938
Published online on: 27 June 2019

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Article Open Access

Expression changes of CX3CL1 and CX3CR1 proteins in the hippocampal CA1 field of the gerbil following transient global cerebral ischemia

Ji Hyeon Ahn, Dae Won Kim, Joon Ha Park, Tae‑Kyeong Lee, Hyang‑Ah Lee, Moo‑Ho Won, Choong‑Hyun Lee
Pages: 939-948
Published online on: 10 July 2019

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Article Open Access

Pistacia weinmannifolia ameliorates cigarette smoke and lipopolysaccharide‑induced pulmonary inflammation by inhibiting interleukin‑8 production and NF‑κB activation

Jae‑Won Lee, Hyung Won Ryu, Su Ui Lee, Min‑Gu Kim, Ok‑Kyoung Kwon, Mun Ok Kim, Tae Kyu Oh, Jae Kyoung Lee, Tae Young Kim, Sang Woo Lee, Sangho Choi, Wan‑Yi Li, Kyung‑Seop Ahn, Sei‑Ryang Oh
Pages: 949-959
Published online on: 20 June 2019

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Article Open Access

Micro‑dimpled surface atelocollagen maintains primary human hepatocytes in culture and may promote their functionality compared with collagen coat culture

Tetsuro Sato, Kayoko Semura, Ichiro Fujimoto
Pages: 960-972
Published online on: 21 June 2019

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Article Open Access

miR-92a-3p promotes the proliferation, migration and invasion of esophageal squamous cell cancer by regulating PTEN Retraction in /10.3892/ijmm.2024.5453

Xin Li, Shuilong Guo, Li Min, Qingdong Guo, Shutian Zhang
Pages: 973-981
Published online on: 27 June 2019

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Article Open Access

Gas6 attenuates lipopolysaccharide‑induced TNF‑α expression and apoptosis in H9C2 cells through NF‑κB and MAPK inhibition via the Axl/PI3K/Akt pathway

Mengfang Li, Jingjing Ye, Guangju Zhao, Guangliang Hong, Xiyi Hu, Kaiqiang Cao, You Wu, Zhongqiu Lu
Pages: 982-994
Published online on: 12 July 2019

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Article Open Access

SIRT1 activation alleviates brain microvascular endothelial dysfunction in peroxisomal disorders

Yunshan Zhang, Guiyun Cui, Yue Wang, Yi Gong, Yulan Wang
Pages: 995-1005
Published online on: 20 June 2019

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Article Open Access

Comparison of the therapeutic effects of adipose‑derived and bone marrow mesenchymal stem cells on erectile dysfunction in diabetic rats

Sansan Chen, Jianbin Zhu, Mingzhu Wang, Yanting Huang, Zhuolin Qiu, Jingjing Li, Xinglu Chen, Huiying Chen, Mingyu Xu, Jun Liu, Miaoqin She, Hongwei Li, Xiaorong Yang, Yi Wang, Xiangsheng Cai
Pages: 1006-1014
Published online on: 24 June 2019

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Article Open Access

Identification of long non‑coding RNA‑mediated transcriptional dysregulation triplets reveals global patterns and prognostic biomarkers for ER+/PR+, HER2‑ and triple negative breast cancer

Zhengwei Du, Wei Gao, Jiayi Sun, Yujing Li, Yu Sun, Tong Chen, Shuke Ge, Wenbin Guo
Pages: 1015-1025
Published online on: 27 June 2019

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Article Open Access

Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway

Jiquan Wang, Yingbing Zhang, Xu Liu, Jizhao Wang, Bin Li, Yongkang Liu, Jiansheng Wang
Pages: 1026-1038
Published online on: 08 July 2019

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Article Open Access

Downregulated miR‑302d‑3p promotes chondrocyte proliferation and migration by regulation of Unc‑51‑like kinase 1

Shangzeng Wang, Yongzhi Zheng, Zheng Hu, Zhen Wang, Yingjie Zhang, Licheng Wei
Pages: 1039-1047
Published online on: 05 July 2019

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Article Open Access

Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy

Li Yao, Hongguang Chen, Qinghua Wu, Keliang Xie
Pages: 1048-1062
Published online on: 03 July 2019

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Article Open Access

Circular RNA profile in liver tissue of EpCAM knockout mice

Yanhong Yang, Shaomin Liu, Zili Lei, Guibin Chen, Li Huang, Fei Yang, Yuting Lei, Yanyan Liu, Lanxiang Yang, Wanwan Liu, Liangxue Lai, Jiao Guo
Pages: 1063-1077
Published online on: 08 July 2019

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Article Open Access

Hypertonic saline downregulates endothelial cell-derived VEGF expression and reduces blood-brain barrier permeability induced by cerebral ischaemia via the VEGFR2/eNOS pathway

Qiaosheng Wang, Yiyu Deng, Linqiang Huang, Wenxin Zeng, Shenglong Chen, Bo Lv, Wenqiang Jiang, Yongli Han, Hongguang Ding, Miaoyun Wen, Hongke Zeng
Pages: 1078-1090
Published online on: 02 July 2019

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Article Open Access

Increased expression of Sonic hedgehog restores diabetic endothelial progenitor cells and improves cardiac repair after acute myocardial infarction in diabetic mice

Qing Xiao, Xiao‑Ya Zhao, Ru‑Chao Jiang, Xiu‑Hui Chen, Xiang Zhu, Kai‑Feng Chen, Sheng‑Ying Chen, Xiao‑Ling Zhang, Yuan Qin, Ying‑Hua Liu, Jian‑Dong Luo
Pages: 1091-1105
Published online on: 16 July 2019

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Article

Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis

Yan Sun, Wensheng Pan, Jun Zhang, Ying Cui, Huiju Wang, Guoqing Ru, Legao Chen
Pages: 1106-1116
Published online on: 08 July 2019

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Article

CaSR activates PKCδ to induce cardiomyocyte apoptosis via ER stress‑associated apoptotic pathways during ischemia/reperfusion

Chong Liu, Huanming Li, Huishuang Zheng, Meili Zhai, Fanghao Lu, Shiyun Dong, Tao Fang, Weihua Zhang
Pages: 1117-1126
Published online on: 24 June 2019

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Article

Alcohol‑induced attenuation of post‑traumatic inflammation is not necessarily liver‑protective following trauma/hemorrhage

Nils Wagner, Scott Dieteren, Niklas Franz, Kernt Köhler, Mario Perl, Ingo Marzi, Borna Relja
Pages: 1127-1138
Published online on: 27 June 2019

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Article

Downregulation of microRNA‑629‑5p in colorectal cancer and prevention of the malignant phenotype by direct targeting of low‑density lipoprotein receptor‑related protein 6 Retraction in /10.3892/ijmm.2021.5057

Guoqiang Yan, Chenyao Li, Yuhang Zhao, Meng Yue, Lei Wang
Pages: 1139-1150
Published online on: 18 June 2019

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Article

Biologically active 1,25-dihydroxyvitamin D3 protects against experimental sepsis by negatively regulating the Toll-like receptor 4/myeloid differentiation primary response gene 88/Toll-IL-1 resistance-domain-containing adapter-inducing interferon-β signaling pathway

Ge Zheng, Na Wen, Minli Pan, Yumao Huang, Zhishu Li
Pages: 1151-1160
Published online on: 05 July 2019

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Article

GLP‑1 improves palmitate‑induced insulin resistance in human skeletal muscle via SIRT1 activity

Ja Young Jeon, Sung‑E Choi, Eun Suk Ha, Han Byeol Lee, Tae Ho Kim, Seung Jin Han, Hae Jin Kim, Dae Jung Kim, Yup Kang, Kwan‑Woo Lee
Pages: 1161-1171
Published online on: 09 July 2019

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Article

MicroRNA-592 suppresses the malignant phenotypes of thyroid cancer by regulating lncRNA NEAT1 and downregulating NOVA1

Yiqiang Luo, Tianwei Hao, Jian Zhang, Ming Zhang, Peng Sun, Lei Wu
Pages: 1172-1182
Published online on: 16 July 2019

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Correction Open Access

[Corrigendum] Alterations in gene expression during sexual differentiation in androgen receptor knockout mice induced by environmental endocrine disruptors

Dehong Liu, Liping Shen, Yonglin Tao, Ying Kuang, Lei Cai, Dan Wang, Meiduo He, Xuebo Tong, Shuguang Zhou, Jie Sun, Chenchen Shi, Chunxiao Wang, Yi Wu
Pages: 1183-1183
Published online on: 11 July 2019

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Review Open Access

Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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