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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2021 Volume 22 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Downregulation of amine oxidase copper containing 1 inhibits tumor progression by suppressing IL‑6/JAK/STAT3 pathway activation in hepatocellular carcinoma

Qian Ding, Dongdong Lin, Yajing Zhou, Feng Li, Jianming  Lai, Jianping Duan, Jing Chen, Caihua Jiang
Article Number: 857
Published online on: 30 October 2021

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Review Open Access

Haematological malignancies implications during the times of the COVID‑19 pandemic (Review)

Eleni Papakonstantinou, Konstantina Dragoumani, Aspasia Efthimiadou, Anastasia Marina Palaiogeorgou, Katerina Pierouli, Thanasis Mitsis, George P. Chrousos, Flora Bacopoulou, Dimitrios Vlachakis
Article Number: 856
Published online on: 29 October 2021

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Article Open Access

Long non‑coding RNA TMPO‑AS1 promotes cell proliferation, migration, invasion and epithelial‑to‑mesenchymal transition in gallbladder carcinoma by regulating the microRNA‑1179/E2F2 axis

Zhenghui Sui, Xin Sui
Article Number: 855
Published online on: 29 October 2021

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Article Open Access

Notch pathway inhibitor DAPT accelerates in vitro proliferation and adipogenesis in infantile hemangioma stem cells

Xing Xu, Yao Wu, Honghong Li, Juan Xie, Dongsheng Cao, Xueying Huang
Article Number: 854
Published online on: 26 October 2021

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Article Open Access

lncRNA FOXD3‑AS1 promotes the progression of non‑small cell lung cancer by regulating the miR‑135a‑5p/CDK6 axis

Haiyan Guo, Shufang Lin, Zhenyong Gan, Jinglian Xie, Jiaming Zhou, Ming Hu
Article Number: 853
Published online on: 26 October 2021

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Article Open Access

Metformin inhibits the proliferation of canine mammary gland tumor cells through the AMPK/AKT/mTOR signaling pathway in vitro

Yuying Fan, Xiaoli Ren, Yingxue Wang, Enshuang Xu, Shuang Wang, Ruidong Ge, Yun Liu
Article Number: 852
Published online on: 26 October 2021

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Article Open Access

Procollagen‑lysine, 2‑oxoglutarate 5‑dioxygenase 1 increases cellular proliferation and colony formation capacity in lung cancer via activation of E2F transcription factor 1

Baijun Li, Hao Yang, Bin Shen, Jianwei Huang, Zhiqiang Qin
Article Number: 851
Published online on: 26 October 2021

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Review Open Access

DCLK1 and its interaction partners: An effective therapeutic target for colorectal cancer (Review)

Muthu Vijai, Mursaleen Baba, Satish Ramalingam, Anand Thiyagaraj
Article Number: 850
Published online on: 26 October 2021

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Article Open Access

Regulatory effect between HMGA2 and the Wnt/β‑catenin signaling pathway in the carcinogenesis of sporadic colorectal tubular adenoma

Dan Li, Yanan Cao, Juan Wang, Haiyan Yang, Weina Liu, Jinfeng Cui, Wenxin Wu
Article Number: 849
Published online on: 25 October 2021

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Article Open Access

Effects of Forkhead box O1 on lipopolysaccharide‑induced mitochondrial dysfunction in human cervical squamous carcinoma SiHa cells

Huizhi Wang, Zhi Ma, Fanshu Gao, Wei Jiang, Yang Li, Shuping Li
Article Number: 848
Published online on: 22 October 2021

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Article Open Access

Knockdown of METTL14 suppresses the malignant progression of non‑small cell lung cancer by reducing Twist expression

Fang Yang, Wei-Qi Yuan, Juan Li, Yi-Qin Luo
Article Number: 847
Published online on: 21 October 2021

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Article Open Access

RNF43 overexpression attenuates the Wnt/β‑catenin signalling pathway to suppress tumour progression in cholangiocarcinoma

Norma Sainstika Pangestu, Piyasiri Chueakwon, Krajang Talabnin, Juthamas Khiaowichit, Chutima Talabnin
Article Number: 846
Published online on: 21 October 2021

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Article Open Access

Temozolomide abrogates the aggressiveness of urothelial carcinoma cells by enhancing senescence and depleting the side population Corrigendum in /10.3892/ol.2026.15710

Na-Yon Kim, Sung-Hyun Hwang, Yeseul Yang, Yongbaek Kim
Article Number: 845
Published online on: 21 October 2021

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Review Open Access

Pathogenicity of the MAGE family (Review)

Sanyan Li, Xiang Shi, Jingping Li, Xianrong Zhou
Article Number: 844
Published online on: 21 October 2021

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Article Open Access

Comprehensive analysis of competitive endogenous RNAs networks reveals potential prognostic biomarkers associated with epithelial ovarian cancer

Wenjuan Wu, Chunhui Gao, Lipai Chen, Donghui Zhang, Suiqun Guo
Article Number: 843
Published online on: 21 October 2021

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Correction Open Access

[Corrigendum] MicroRNA-1258: An invasion and metastasis regulator that targets heparanase in gastric cancer

Jinxin Shi, Ping Chen, Jingxu Sun, Yongxi Song, Bin Ma, Peng Gao, Xiaowan Chen, Zhenning Wang
Article Number: 842
Published online on: 20 October 2021

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Article Open Access

miR‑152‑mediated MKK7 downregulation is attenuated by MYCNOS in ovarian adenocarcinoma

Guifang Zhang, Dan Zheng, Xiaoqing Chen, Li Li, Jingrong Yu
Article Number: 841
Published online on: 20 October 2021

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Article Open Access

Integrative meta‑analysis of gene expression profiles identifies FEN1 and ENDOU as potential diagnostic biomarkers for cervical squamous cell carcinoma

Vladimir Basic, Boxi Zhang, Jakob Domert, Ulrika Pellas, Tibor Tot
Article Number: 840
Published online on: 19 October 2021

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Article Open Access

Circular RNA FOXO3 accelerates glycolysis and improves cisplatin sensitivity in lung cancer cells via the miR‑543/Foxo3 axis

Yanni Zhang, Pan Ge, Dangxia Zhou, Rong Xing, Lizhi Bai
Article Number: 839
Published online on: 18 October 2021

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Article

MI‑773, a breaker of the MDM2/p53 axis, exhibits anticancer effects in neuroblastoma via downregulation of INSM1

Yan-Ling Chen, Zi-Mu Zhang, Xiao-Lu Li, Yan-Fang Tao, Shui-Yan Wu, Fang Fang, Yi Xie, Xin-Mei Liao, Gen Li, Di Wu, Hai-Rong Wang, Ran Zuo, Hai-Bo Cao, Jing-Jing Pan, Juan-Juan Yu, Zheng Zhang, Xin-Ran Chu, Yong-Ping Zhang, Chen-Xi Feng, Jian-Wei Wang, Jun Lu, Shao-Yan Hu, Zhi-Heng Li, Jian Pan
Article Number: 838
Published online on: 18 October 2021

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Article Open Access

Prognostic value of the density of tumor‑infiltrating lymphocytes in colorectal cancer liver metastases

En Wang, Masatsune Shibutani, Hisashi Nagahara, Tatsunari Fukuoka, Yasuhito Iseki, Yuki Okazaki, Shinichiro Kashiwagi, Hiroaki Tanaka, Kiyoshi Maeda
Article Number: 837
Published online on: 18 October 2021

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Review Open Access

Tertiary lymphoid structure and B‑cell‑related pathways: A potential target in tumor immunotherapy (Review)

Meng Qin, Ying Jin, Ling-Ya Pan
Article Number: 836
Published online on: 18 October 2021

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Article Open Access

Involvement of PBRM1 in VHL disease‑associated clear cell renal cell carcinoma and its putative relationship with the HIF pathway

Sophie Gad, Gwenaël Le Teuff, Baptiste Nguyen, Virginie Verkarre, Veronique Duchatelle, Vincent Molinie, Katia Posseme, Benjamin Grandon, Melanie Da Costa, Bastien Job, Guillaume Meurice, Nathalie Droin, Arnaud Mejean, Sophie Couve, Flore Renaud, Betty Gardie, Bin Tean Teh, Stephane Richard, Sophie Ferlicot
Article Number: 835
Published online on: 15 October 2021

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Review Open Access

Annexin A3 and cancer (Review)

Chao Liu, Nannan Li, Guijian Liu, Xue Feng
Article Number: 834
Published online on: 14 October 2021

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Article Open Access

MicroRNA‑3907 promotes the proliferation and migration of sebaceous gland carcinoma of the eyelid by targeting thrombospondin 1

Chuanli Zhang, Limin Zhu, Xun Liu, Meixia Jiang, Qin Tang, Fei Xu, Tingting Lin, Lijie Dong, Yanjin He
Article Number: 833
Published online on: 14 October 2021

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Article Open Access

Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways Expression of Concern in /10.3892/ol.2026.15565

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 832
Published online on: 14 October 2021

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Article Open Access

Ratio of the expression levels of androgen receptor splice variant 7 to androgen receptor in castration refractory prostate cancer

Yoshitaka Sekine, Hiroshi Nakayama, Yoshiyuki Miyazawa, Seiji Arai, Hidekazu Koike, Hiroshi Matsui, Yasuhiro Shibata, Kazuto Ito, Kazuhiro Suzuki
Article Number: 831
Published online on: 13 October 2021

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Article Open Access

Integrated bioinformatics analyses of key genes involved in hepatocellular carcinoma immunosuppression

Hongyan Huang, Youwen Hu, Li Guo, Zhili Wen
Article Number: 830
Published online on: 13 October 2021

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Article Open Access

Role of uromodulin and complement activation in the progression of kidney disease

Fei Shen, Maojing Liu, Fei Pei, Li Yu, Xiangdong Yang
Article Number: 829
Published online on: 13 October 2021

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Article Open Access

Silencing of NACC1 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells via regulating the AKT/mTOR signaling pathway

Zhengyong Cao, Hong Chen, Xiaoli Mei, Xiaobo Li
Article Number: 828
Published online on: 12 October 2021

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Article

Sorafenib treatment of metastatic melanoma with c‑Kit aberration reduces tumor growth and promotes survival

Tomoya Takeda, Masanobu Tsubaki, Natsuki Kato, Shuji Genno, Eri Ichimura, Aya Enomoto, Motohiro Imano, Takao Satou, Shozo Nishida
Article Number: 827
Published online on: 12 October 2021

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Review Open Access

Exosomal circular RNAs: A new frontier in the metastasis of digestive system tumors (Review)

Baile Shen, Keke Sun
Article Number: 826
Published online on: 12 October 2021

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Article Open Access

lncRNA DSCAM‑AS1 facilitates the progression of endometrial cancer via miR‑136‑5p

Luhong Li, Peipei Chen, Bingbing Huang, Peiya Cai
Article Number: 825
Published online on: 12 October 2021

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Article

KLK6 mediates stemness and metabolism of gastric carcinoma cells via the PI3K/AKT/mTOR signaling pathway

Dong Zhou, Yanping He, Hengping Li, Weidong Huang
Article Number: 824
Published online on: 12 October 2021

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Article Open Access

New prognostic factors and scoring system for patients with acute myeloid leukemia

Ye Kuang, Yang Wang, Xianghong Cao, Chuanmei Peng, Hui Gao
Article Number: 823
Published online on: 11 October 2021

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Article Open Access

Aberrant expression of SFRP1, SFRP3, DVL2 and DVL3 Wnt signaling pathway components in diffuse gastric carcinoma

Maja Sremac, Frane Paic, Katja Grubelic Ravic, Ljiljana Serman, Aja Pavicic Dujmovic, Iva Brcic, Zeljko Krznaric, Tamara Nikuseva Martic
Article Number: 822
Published online on: 08 October 2021

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Review Open Access

Pembrolizumab in endometrial cancer: Where we stand now (Review)

Aikaterini Aravantinou‑Fatorou, Angeliki Andrikopoulou, Michael Liontos, Oraianthi Fiste, Vasiliki E. Georgakopoulou, Meletios-Athanasios Dimopoulos, Maria Gavriatopoulou, Flora Zagouri
Article Number: 821
Published online on: 08 October 2021

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Article Open Access

Membranous CD44v6 is upregulated as an early event in colorectal cancer: Downregulation is associated with circulating tumor cells and poor prognosis

Agapi Kataki, Vassilis G. Giannakoulis, Anastasia Derventzi, Konstantinos Papiris, Eythimios Koniaris, Manousos Konstadoulakis
Article Number: 820
Published online on: 08 October 2021

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Article

Exosomal miRNA profiles of triple‑negative breast cancer in neoadjuvant treatment

Aiko Sueta, Yoshitaka Fujiki, Lisa Goto‑Yamaguchi, Mai Tomiguchi, Mutsuko Yamamoto‑Ibusuki, Hirotaka Iwase, Yutaka Yamamoto
Article Number: 819
Published online on: 05 October 2021

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Article Open Access

Long non‑coding RNA SNHG17 promotes lung adenocarcinoma progression by targeting the microRNA‑193a‑5p/NETO2 axis

Zhiwei Zhang, Yulan Yan, Bin Zhang, Yuchen Ma, Chen Chen, Changli Wang
Article Number: 818
Published online on: 05 October 2021

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Review Open Access

Circular RNA regulates the onset and progression of cancer through the mitogen‑activated protein kinase signaling pathway (Review)

Qun Lai, Min Wang, Chunmei Hu, Yan Tang, Yarong Li, Shuhong Hao
Article Number: 817
Published online on: 05 October 2021

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Article Open Access

MicroRNA‑100 inhibits breast cancer cell proliferation, invasion and migration by targeting FOXA1

Haihui Xie, Ruobing Xiao, Yaolin He, Lingzhi He, Changjun Xie, Juan Chen, Yan Hong
Article Number: 816
Published online on: 01 October 2021

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Article Open Access

G2/M cell cycle arrest and apoptosis induced by COH‑203 in human promyelocytic leukemia HL‑60 cells

Jihong Lin, Lei Zhang, Zhiwei Wang, Qi Guan, Kai Bao, Lan Wu
Article Number: 815
Published online on: 28 September 2021

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Article Open Access

Cancer‑associated fibroblast‑secreted collagen triple helix repeat containing‑1 promotes breast cancer cell migration, invasiveness and epithelial‑mesenchymal transition by activating
the Wnt/β‑catenin pathway

Huixin Li, Wei Liu, Xiaoyu Zhang, Yongfeng Wang
Article Number: 814
Published online on: 28 September 2021

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Article

Short 57 kb CDKN2A FISH probe effectively detects short homozygous deletion of the 9p21 locus in malignant pleural mesothelioma

Yuzo Oyama, Makoto Hamasaki, Shinji Matsumoto, Ayuko Sato, Tohru Tsujimura, Kazuki Nabeshima
Article Number: 813
Published online on: 28 September 2021

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Article Open Access

MicroRNA‑23b‑3p targets non‑SMC condensing I complex subunit G to promote proliferation and inhibit apoptosis of colorectal cancer cells via regulation of the PI3K/AKT signaling pathway

Peidong Li, Jing Wen, Xiru Ren, Yu Zhou, Yuan Xue, Zaihua Yan, Shengjie Li, Hongpeng Tian, Xue-Gui Tang, Guang-Jun Zhang
Article Number: 812
Published online on: 28 September 2021

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Review Open Access

Emerging role of BAD and DAD1 as potential targets and biomarkers in cancer (Review)

Yulou Luo, You Wu, Hai Huang, Na Yi, Yan Chen
Article Number: 811
Published online on: 28 September 2021

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Journal Cover
September-2026 Volume 32 Issue 3

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article

FOXA2 enhances anoikis sensitivity in lung adenocarcinoma cells: Dual role of ABCA8 upregulation and NOX4 suppression

Nina Hu, Ling Li, Jianqing Hao, Lifang Li, Mengmeng Pan, Jia He
Article Number: 422
Published online on: 22 July 2026

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Correction Open Access

[Corrigendum] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 421
Published online on: 21 July 2026

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Review Open Access

Neoadjuvant therapy for stage II‑III triple‑negative breast cancer: Current evidence, clinical boundaries and emerging strategies (Review)

Bingchen Li, Xinchen Tian, Qing-Qing Yu, Hongxia Cui
Article Number: 420
Published online on: 21 July 2026

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Article Open Access

Keratin gene expression signature predicts prognosis and immunotherapy efficacy in lung adenocarcinoma

Aohui Chen, Ting Gao, Fengqi Liu, Mingyue Zhao, Ruizhen Bai, Quan Liu
Article Number: 419
Published online on: 21 July 2026

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Article Open Access

Prognostic value of nutritional and inflammatory biomarkers in patients with non‑small cell lung cancer and bone metastasis: A retrospective study

Yuanjiao Chen, Lu Zhang, Shuting Wang, Huangren Zou, Yanlin Liu, Yuke Bai, Zhiyong Deng, Chao Liu, Suyun Yang
Article Number: 418
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Effects of FHIT gene on proliferation and apoptosis of osteosarcoma cells

Zhengfeng Xu, Jiajun Wu, Pan Cai, Xiaoxiao Zhou, Cunguo Yi, Bin Wang
Article Number: 417
Published online on: 20 July 2026

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Review

Ferroptosis regulatory networks as therapeutic sensitizers in combination therapy for hepatocellular carcinoma (Review)

Mengxiao Zhu, Xiaoxiong Hu
Article Number: 416
Published online on: 17 July 2026

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Article Open Access

 Establishment of extrahepatic bile duct cancer organoids using suspension culture and their application in clinical drug screening

Wei Huang, Yuanhui Su, Cheng Yu, Yanlong Zhang, Hao Xu, Wence Zhou
Article Number: 415
Published online on: 17 July 2026

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Review Open Access

Systems biology of Wnt signaling in glioma chemotherapy resistance: Integrating multi‑omics mechanisms and emerging therapeutic vulnerabilities (Review)

Qianru Zeng, Zhuojun Chen, Rendong Zhang, Hongchao Pan
Article Number: 414
Published online on: 17 July 2026

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Article Open Access

A three‑gene signature correlated with MAPK/ERK activation characterizes acquired resistance to EGFR‑tyrosine kinase inhibitors in non‑small cell lung cancer

Changtai Qin, Wei Zhang, Dongfang Tang, Yuxi Yang, Binghui Liang, Zhiming Hu, Yuxiao Zhang, Tingjie Ye, Wei Xu
Article Number: 413
Published online on: 17 July 2026

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Review Open Access

Role of PCSK9 in hallmarks of cancer: From mechanisms to interventions (Review)

Lijuan Tang, Shu Yao, Yongheng Zhu, Zongsheng He, Bruno Ramos‑Molina, Yuanchun Xu
Article Number: 412
Published online on: 15 July 2026

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Article Open Access

PRR11 expression in early ER+/HER2‑low breast cancer: Association with estrogen receptor positivity and exploratory analysis of prognostic significance

Alper Turkel, Mutlu Dogan, Sultan Cigdem Irkkan, Haktan Bagis Erdem, Nazan Bozdogan, Taha Bahsi
Article Number: 411
Published online on: 15 July 2026

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Expression of Concern Open Access

[Expression of Concern] Elevated microRNA‑125b levels predict a worse prognosis in HER2‑positive breast cancer patients  

Yanwei Luo, Xinye Wang, Weihong Niu, Heran Wang, Qiuyuan Wen, Songqing Fan, Ran Zhao, Zheng Li, Wei Xiong, Shuping Peng, Zhaoyang Zeng, Xiaoling Li, Guiyuan Li, Ming Tan, Ming Zhou
Article Number: 410
Published online on: 15 July 2026

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Article Open Access

Association between the presence of EGFR or ALK mutations and the location of primary non‑small cell lung cancer, as well as metabolic activity observed on 18F‑FDG PET/CT scans

Inci Uslu Biner, Tuba Inal Cengiz, Ulku Yilmaz, Nalan Akyurek, Suna Kavurgaci, Pinar Akin Kabalak, Derya Kizilgoz, Ezgi Gurel Akan
Article Number: 409
Published online on: 14 July 2026

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Review Open Access

Advances in Helicobacter pylori-mediated oncogenic signaling pathways in gastric cancer: From pathological evolution to clinical application prospects (Review)

Tingting Ding, Wenjun Hu, Xiaogai Qi, Yakun Zhang, Hui Wang
Article Number: 408
Published online on: 14 July 2026

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Article

Clinical and biological significance of TROY (TNFRSF19) splice variants in colorectal cancer

Mitsuaki Nishioka, Yuki Kunimune, Yutaka Suehiro, Masaki Kodama, Akiyo Ishiguro, Tatsuya Takagi, Jun Nishikawa, Hidenori Takahashi, Hiroto Matsui, Shinobu Tomochika, Koichi Hamabe, Shinichi Hashimoto, Hiroaki Nagano, Taro Takami, Takahiro Yamasaki
Article Number: 407
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Sirtuin 7 promotes glioma proliferation and invasion through activation of the ERK/STAT3 signaling pathway

Pengfei Mu, Kun Liu, Qingyuan Lin, Wensheng Yang, Dan Liu, Zhen Lin, Wei Shao, Tianhai Ji
Article Number: 406
Published online on: 13 July 2026

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Article

Molecular signatures of triple‑negative breast cancer cells acquiring palbociclib resistance via continuous exposure

Daichi Enomoto, Yumika Iwasa, Natsuho Irie, Haruki Ohata, Yuki Uemichi, Miyuki Mabuchi, Tadashi Shimizu, Kohji Takara
Article Number: 405
Published online on: 10 July 2026

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Review Open Access

Gastrointestinal conventional carcinoma with neuroendocrine differentiation: From pathological phenomenon to clinical importance (Review)

Chenyang Zhou, Shizheng Tong, Danfeng Zhou, Yixin Pan, Jingjing Xu, Sunbin Ling, Wei Wu, Tingting Feng
Article Number: 404
Published online on: 09 July 2026

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Review Open Access

Cell‑cycle reactivation and hepatocyte identity loss in hepatocellular carcinoma: Transcriptomic hallmarks and validation strategies (Review)

Jichen Hou, Bing Zhu, Lu Liang
Article Number: 403
Published online on: 09 July 2026

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Case Report Open Access

Primary thymic papillary adenocarcinoma with a rare CD5/CD117‑negative and PAX8/WT1‑positive immunophenotype: A case report

Dequan Zhu, Chuanzhen Wan, Jialong Guo, Tao Zeng, Wei Wang
Article Number: 402
Published online on: 09 July 2026

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Expression of Concern Open Access

[Expression of Concern] Fatty acids inhibit anticancer effects of 5‑fluorouracil in mouse cancer cell lines

Eriko Tanabe, Misaho Kitayoshi, Kiyomu Fujii, Hitoshi Ohmori, Yi Luo, Yui Kadochi, Shiori Mori, Rina Fujiwara, Yukiko Nishiguchi, Takamitsu Sasaki, Hiroki Kuniyasu
Article Number: 401
Published online on: 09 July 2026

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Article Open Access

A nomogram prediction model for brain metastases in patients with lung adenocarcinoma 

Hao Liu, Lan Wang, Xiaolei Zhuo, Yucheng Hu, Ziming Li, Huishan Deng, Mingshu Mo
Article Number: 400
Published online on: 08 July 2026

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Article Open Access

Survival benefits of non‑surgical triple therapy in hepatocellular carcinoma with inferior vena cava/right atrial tumor thrombus: A retrospective analysis from a multidisciplinary team

Peng Tang, Jin Li, Jiayu Duan, Xin Wang, Jin Zhou, Yu Yang, Yong Zeng
Article Number: 399
Published online on: 08 July 2026

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Article Open Access

A bioinformatics analysis of KIF transcriptomic subtyping reveals prognostic heterogeneity and differential therapeutic responses in cervical cancer

Xinyi Zhao, Jie Wu, Lan Li, Haohan Zhang, Jing Li, Hao Zhong, Yuchao Dan, Qibin Song, Hongbin Chen, Bin Xu
Article Number: 398
Published online on: 08 July 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA OIP5‑AS1 promotes the progression of esophageal cancer by regulating miR‑30a/VOPP1 expression

Jiajun Xu, Zhixi Chen, Zheng Fang, Shixiong Chen, Ying Guo, Xianfeng Liu, Kai Chen, Shengjia Chen
Article Number: 397
Published online on: 08 July 2026

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Article Open Access

FUBP3 regulates expression and alternative splicing of genes associated with cell proliferation and apoptosis in cancer cells

Lingyu Kong, Chaoxu Fu, Xuesong Li, Mingxin Chen, Xinqi Liu, Min Zhou, Tongshu Wang, Hongxin Piao
Article Number: 396
Published online on: 07 July 2026

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Article

Pan‑immune‑inflammation value as a prognostic and predictive biomarker in metastatic non‑small cell lung cancer treated with nivolumab: A real‑world study

Nedim Turan, Hacer Sahika Yildiz, Sedat Yildirim, Ezgi Turkoglu, Ugur Ozkerim, Sila Oksuz, Neslihan Buyukmurat, Hamit Bal, Heves Surmeli, Hatice Odabas
Article Number: 395
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] miR‑5590‑3p inhibits the proliferation and metastasis of renal cancer cells by targeting ROCK2 to inhibit proliferation, migration and invasion

Queling Liu, Anyi Zhu, Weiyin Gao, Fu Gui, Yan Zou, Xiaocheng Zhou, Zhengdong Hong
Article Number: 394
Published online on: 06 July 2026

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Article

Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer

Jinfen Yao, Jie Chen
Article Number: 393
Published online on: 03 July 2026

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Review Open Access

Regulatory roles of N6‑methyladenosine methylation factors in melanoma invasion and metastasis (Review)

Zhijie Xu, Wanqun Yu, Jie Liu, Xiyue Chang, Shiraz Manji Laeeqa, Zerong Xu, Qi Yang, Wanan Xiao
Article Number: 392
Published online on: 03 July 2026

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Review

Microbiota in pancreatic cancer: Roles in tumor initiation and progression (Review)

Yanjun Lou, Yiqun Fan
Article Number: 391
Published online on: 03 July 2026

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Review Open Access

Role of long non‑coding RNA HCG11 in human cancers: From molecular mechanisms to clinical applications (Review)

Qiong-Feng Tan, Bo Chen, Hai-Feng Hu, Huang Liu, Wen Huang, Wei Mu
Article Number: 390
Published online on: 03 July 2026

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Expression of Concern Open Access

[Expression of Concern] Endosialin/CD248 may be a potential therapeutic target to prevent the invasion and metastasis in osteosarcoma

Yumiko Kondo, Kanya Honoki, Shingo Kishi, Shiori Mori, Rina Fujiwara‑Tani, Shinji Tsukamoto, Hiromasa Fujii, Hiroki Kuniyasu, Yasuhito Tanaka
Article Number: 389
Published online on: 03 July 2026

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Review Open Access

Emerging roles of O‑GlcNAcylation in tumorigenesis, immunosuppression and drug resistance (Review)

Yuntong Liu, Yumo Han, Shumei Ding, Han Deng, Shiyue Li, Yingyu Zhang, Haimeng Yin, Bo You
Article Number: 388
Published online on: 02 July 2026

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Article Open Access

Efficacy and safety of immune checkpoint inhibitors combined with anti‑angiogenic agents for advanced cervical cancer: A systematic review and meta‑analysis

Hengchang Chen, Xue Yang, Yulu Qin, Wentong Xu, Mingzhu Jiao, Xinyu Lu, Yaxu Su, Fengjuan Zhou, Yong Xin
Article Number: 387
Published online on: 02 July 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo targeting of bladder carcinoma with metformin in combination with cisplatin

Dong Wang, Xiaohou Wu
Article Number: 386
Published online on: 02 July 2026

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Article Open Access

Lymphocyte‑to‑C‑reactive protein ratio as a clinically feasible nutrition‑inflammation marker for predicting outcomes in patients with gastric cancer

Kai Liu, Lai Chang
Article Number: 385
Published online on: 02 July 2026

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Article Open Access

Identification and validation of aging‑related genes in patients with multiple myeloma

Huajing Liu, Senhua Song, Yingtao Wu, Yu Wang, Yueping Liu, Ying Liu
Article Number: 384
Published online on: 02 July 2026

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Retraction Open Access

[Retracted] miR‑331‑3p suppresses cell invasion and migration in colorectal carcinoma by directly targeting NRP2

Hongye Zhang, Ruiyu Wang, Mingxia Wang
Article Number: 383
Published online on: 01 July 2026

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Article Open Access

Air pollution and hepatocellular carcinoma: Integrated network toxicology, machine learning, molecular docking and multiomics analysis

Xiaorong Wang, Huihao Qin, Jing Jing, Yun Liu, Lei Guo, Hongquan Liu, Wei Zhang
Article Number: 382
Published online on: 30 June 2026

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Case Report Open Access

Cervical metastasis in breast cancer: A case report

Xinru Liu, Ke Sun, Hongming Zhu, Tonghua Du, Liyang Sheng, Bin Liu
Article Number: 381
Published online on: 30 June 2026

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Review Open Access

New and emerging strategies for targeting cancers: Challenges and opportunities (Review)

Sreenivasa R. Chinni, Arun K. Rishi, Kaladhar B. Reddy
Article Number: 380
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑663b enhances migration and invasion by targeting adenomatous polyposis coli 2 in colorectal carcinoma cells

Fenqiang Xiao, Wangbin Chen, Chao Yu, Gang Zhao
Article Number: 379
Published online on: 29 June 2026

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October-2026 Volume 32 Issue 4

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Claudin‑18.2: Molecular mechanisms to clinical translation in solid tumors (Review)

Minjie Zhang, Dawei Wu, Yu Tang, Ning Li, Xinhua Yan
Article Number: 459
Published online on: 12 August 2026

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Case Report Open Access

Probable cavernous sinus‑adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang
Article Number: 458
Published online on: 12 August 2026

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Case Report Open Access

Immunotherapy combined with anti‑angiogenic therapy, radiotherapy and chemotherapy for the treatment of giant pelvic osteosarcoma: A case report and literature review

Qingying Yan, Jiewen Yang, Yunxia Liu, Miao Cheng, Zhen Wang, Jialu Chen, Yefeng Xu
Article Number: 457
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway

Hai-Jun Li, Jun-Ke Fu, Xiang-Ming Che, Lin Fan, Yong Zhang, E  Bai
Article Number: 456
Published online on: 12 August 2026

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Article Open Access

Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells

Meng Zhang, Xiaoxue Zhang, Qian Rou, Ying Liu, Ailifeire Abudujiapaer, Minghui Li, Huaixiong Wang, Fang Cheng
Article Number: 455
Published online on: 12 August 2026

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Retraction Open Access

[Retracted] 2’,4’‑dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC‑3 human prostate cancer cell growth by induction of apoptosis 

Yuqing Sheng, Mingchang Zou, Yan Wang, Qiheng Li
Article Number: 454
Published online on: 11 August 2026

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Case Report Open Access

Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report

Liwei Zhao, Jiaguo Huang, Zhanwen Dong, Ji Sun, Runmiao Hua, Xuliang Wang, Kai Wang
Article Number: 453
Published online on: 10 August 2026

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Case Report Open Access

Primary leiomyosarcoma of the lumbar soft tissue treated with multimodal therapy, including anlotinib: A case report

Jia-Huan Li, De-Xiang Liao, Zhen Hu, Zhi-Yong Zhang, Dan-Dan Ma, Wei-Dong Jin, Tao Fu
Article Number: 452
Published online on: 10 August 2026

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Expression of Concern Open Access

[Expression of Concern] Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Article Number: 451
Published online on: 07 August 2026

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Article Open Access

Prognostic value of the CONUT score in newly diagnosed diffuse large B‑cell lymphoma

Sema Seçi̇lmi̇ş, Hacer Berna Afacan Öztürk, Bi̇rgül Ay Karakuş, Asena Di̇kyar, Kadi̇r Acar, Ahmet Kürşad Güneş
Article Number: 450
Published online on: 06 August 2026

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Article Open Access

DHX15 as a novel immune‑related prognostic biomarker in breast cancer: An integrated bioinformatics analysis with in vitro functional validation

Fan Li, Qin Yue, Jing Li
Article Number: 449
Published online on: 05 August 2026

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Case Report Open Access

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK‑positive metastatic non‑small cell lung cancer: A case report

Alizée Simon, Gautier Treffel, Guillaume Pax, Guillaume Gauchotte, Marie Husson, Idrissia Hanriot, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Article Number: 448
Published online on: 05 August 2026

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Expression of Concern Open Access

[Expression of Concern] Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation  

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 447
Published online on: 05 August 2026

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Article

Preliminary study on the efficacy of pazopanib combined with toripalimab as first‑line therapy for metastatic renal cell carcinoma: Real‑world data from a single center

Bin Wang, Tianjun Xing, Hongyu Liu, Xuebing Han, Kai Wu
Article Number: 446
Published online on: 05 August 2026

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Review Open Access

Subtype‑specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review)

Yidan Ran
Article Number: 445
Published online on: 04 August 2026

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Review Open Access

Chrono‑immunotherapy in genitourinary oncology: From emerging evidence to clinical translation (Review)

Osama Zein Deen, Xin Ye, Patsy Lee, Roxana Astani, Georg Bjarnason, Christian Kollmannsberger, Bernhard Eigl, Guliz Ozgun
Article Number: 444
Published online on: 03 August 2026

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Article Open Access

Imaging features and clinical management of mesenteric cavernous lymphangioma: A case report and literature review

Zhongze Zhao, Ermin Cai, Tong Zhou, Jianju Feng, Lingzhi Gu
Article Number: 443
Published online on: 03 August 2026

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Article Open Access

Association between the expression of GSTP1 and mutant p53, poor chemotherapy response and metastasis in patients with osteosarcoma

Bangkit Primayudha, Evelina Kodrat, Yogi Prabowo, Aryadi Kurniawan, Nurjati Chairani Siregar, Muhamad Naseh Sajadi Budi Irawan, Rahadyan Magetsari, I Gede Eka Wiratnaya, Istan Irmansyah Irsan, Achmad Fauzi Kamal
Article Number: 442
Published online on: 03 August 2026

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Article Open Access

Astragaloside IV suppresses triple‑negative breast cancer cell migration and invasion by targeting BCAT1‑mediated branched‑chain amino acid metabolism

Yi-Ting Liu, Lu Zhang, Xiao-Dong Sun
Article Number: 441
Published online on: 03 August 2026

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Article Open Access

LC‑MS/MS‑based clinical value exploration of the methionine cycle in luminal breast cancer

Wenxuan Wu, Yifeng Tu, Han Yao, Yajun Mao, Changfei Mao, Feifei Xu, Zhongcheng Wang
Article Number: 440
Published online on: 03 August 2026

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Article

Accuracy of percutaneous ultrasound‑guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease

Camilla Mazzoni, Lisa Argnani, Davide Di Benedetto, Sofia Maria Bakken, Beatrice Casadei, Cinzia Pellegrini, Leonardo De Marco, Marta Machado, Alessandro Broccoli, Pier Luigi Zinzani, Carla Serra
Article Number: 439
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA‑miRNA‑mRNA ceRNA networks

Qian Xu, Xiyun Jia, Qian Wu, Lei Shi, Zihan Ma, Nan Ba, Han Zhao, Xingzhou Xia, Zisen Zhang
Article Number: 438
Published online on: 03 August 2026

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Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Review Open Access

Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Article Open Access

Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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Article Open Access

A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Case Report Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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