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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2021 Volume 22 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Downregulation of amine oxidase copper containing 1 inhibits tumor progression by suppressing IL‑6/JAK/STAT3 pathway activation in hepatocellular carcinoma

Qian Ding, Dongdong Lin, Yajing Zhou, Feng Li, Jianming  Lai, Jianping Duan, Jing Chen, Caihua Jiang
Article Number: 857
Published online on: 30 October 2021

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Review Open Access

Haematological malignancies implications during the times of the COVID‑19 pandemic (Review)

Eleni Papakonstantinou, Konstantina Dragoumani, Aspasia Efthimiadou, Anastasia Marina Palaiogeorgou, Katerina Pierouli, Thanasis Mitsis, George P. Chrousos, Flora Bacopoulou, Dimitrios Vlachakis
Article Number: 856
Published online on: 29 October 2021

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Article Open Access

Long non‑coding RNA TMPO‑AS1 promotes cell proliferation, migration, invasion and epithelial‑to‑mesenchymal transition in gallbladder carcinoma by regulating the microRNA‑1179/E2F2 axis

Zhenghui Sui, Xin Sui
Article Number: 855
Published online on: 29 October 2021

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Article Open Access

Notch pathway inhibitor DAPT accelerates in vitro proliferation and adipogenesis in infantile hemangioma stem cells

Xing Xu, Yao Wu, Honghong Li, Juan Xie, Dongsheng Cao, Xueying Huang
Article Number: 854
Published online on: 26 October 2021

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Article Open Access

lncRNA FOXD3‑AS1 promotes the progression of non‑small cell lung cancer by regulating the miR‑135a‑5p/CDK6 axis

Haiyan Guo, Shufang Lin, Zhenyong Gan, Jinglian Xie, Jiaming Zhou, Ming Hu
Article Number: 853
Published online on: 26 October 2021

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Article Open Access

Metformin inhibits the proliferation of canine mammary gland tumor cells through the AMPK/AKT/mTOR signaling pathway in vitro

Yuying Fan, Xiaoli Ren, Yingxue Wang, Enshuang Xu, Shuang Wang, Ruidong Ge, Yun Liu
Article Number: 852
Published online on: 26 October 2021

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Article Open Access

Procollagen‑lysine, 2‑oxoglutarate 5‑dioxygenase 1 increases cellular proliferation and colony formation capacity in lung cancer via activation of E2F transcription factor 1

Baijun Li, Hao Yang, Bin Shen, Jianwei Huang, Zhiqiang Qin
Article Number: 851
Published online on: 26 October 2021

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Review Open Access

DCLK1 and its interaction partners: An effective therapeutic target for colorectal cancer (Review)

Muthu Vijai, Mursaleen Baba, Satish Ramalingam, Anand Thiyagaraj
Article Number: 850
Published online on: 26 October 2021

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Article Open Access

Regulatory effect between HMGA2 and the Wnt/β‑catenin signaling pathway in the carcinogenesis of sporadic colorectal tubular adenoma

Dan Li, Yanan Cao, Juan Wang, Haiyan Yang, Weina Liu, Jinfeng Cui, Wenxin Wu
Article Number: 849
Published online on: 25 October 2021

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Article Open Access

Effects of Forkhead box O1 on lipopolysaccharide‑induced mitochondrial dysfunction in human cervical squamous carcinoma SiHa cells

Huizhi Wang, Zhi Ma, Fanshu Gao, Wei Jiang, Yang Li, Shuping Li
Article Number: 848
Published online on: 22 October 2021

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Article Open Access

Knockdown of METTL14 suppresses the malignant progression of non‑small cell lung cancer by reducing Twist expression

Fang Yang, Wei-Qi Yuan, Juan Li, Yi-Qin Luo
Article Number: 847
Published online on: 21 October 2021

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Article Open Access

RNF43 overexpression attenuates the Wnt/β‑catenin signalling pathway to suppress tumour progression in cholangiocarcinoma

Norma Sainstika Pangestu, Piyasiri Chueakwon, Krajang Talabnin, Juthamas Khiaowichit, Chutima Talabnin
Article Number: 846
Published online on: 21 October 2021

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Article Open Access

Temozolomide abrogates the aggressiveness of urothelial carcinoma cells by enhancing senescence and depleting the side population

Na-Yon Kim, Sung-Hyun Hwang, Yeseul Yang, Yongbaek Kim
Article Number: 845
Published online on: 21 October 2021

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Review Open Access

Pathogenicity of the MAGE family (Review)

Sanyan Li, Xiang Shi, Jingping Li, Xianrong Zhou
Article Number: 844
Published online on: 21 October 2021

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Article Open Access

Comprehensive analysis of competitive endogenous RNAs networks reveals potential prognostic biomarkers associated with epithelial ovarian cancer

Wenjuan Wu, Chunhui Gao, Lipai Chen, Donghui Zhang, Suiqun Guo
Article Number: 843
Published online on: 21 October 2021

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Correction Open Access

[Corrigendum] MicroRNA-1258: An invasion and metastasis regulator that targets heparanase in gastric cancer

Jinxin Shi, Ping Chen, Jingxu Sun, Yongxi Song, Bin Ma, Peng Gao, Xiaowan Chen, Zhenning Wang
Article Number: 842
Published online on: 20 October 2021

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Article Open Access

miR‑152‑mediated MKK7 downregulation is attenuated by MYCNOS in ovarian adenocarcinoma

Guifang Zhang, Dan Zheng, Xiaoqing Chen, Li Li, Jingrong Yu
Article Number: 841
Published online on: 20 October 2021

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Article Open Access

Integrative meta‑analysis of gene expression profiles identifies FEN1 and ENDOU as potential diagnostic biomarkers for cervical squamous cell carcinoma

Vladimir Basic, Boxi Zhang, Jakob Domert, Ulrika Pellas, Tibor Tot
Article Number: 840
Published online on: 19 October 2021

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Article Open Access

Circular RNA FOXO3 accelerates glycolysis and improves cisplatin sensitivity in lung cancer cells via the miR‑543/Foxo3 axis

Yanni Zhang, Pan Ge, Dangxia Zhou, Rong Xing, Lizhi Bai
Article Number: 839
Published online on: 18 October 2021

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Article

MI‑773, a breaker of the MDM2/p53 axis, exhibits anticancer effects in neuroblastoma via downregulation of INSM1

Yan-Ling Chen, Zi-Mu Zhang, Xiao-Lu Li, Yan-Fang Tao, Shui-Yan Wu, Fang Fang, Yi Xie, Xin-Mei Liao, Gen Li, Di Wu, Hai-Rong Wang, Ran Zuo, Hai-Bo Cao, Jing-Jing Pan, Juan-Juan Yu, Zheng Zhang, Xin-Ran Chu, Yong-Ping Zhang, Chen-Xi Feng, Jian-Wei Wang, Jun Lu, Shao-Yan Hu, Zhi-Heng Li, Jian Pan
Article Number: 838
Published online on: 18 October 2021

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Article Open Access

Prognostic value of the density of tumor‑infiltrating lymphocytes in colorectal cancer liver metastases

En Wang, Masatsune Shibutani, Hisashi Nagahara, Tatsunari Fukuoka, Yasuhito Iseki, Yuki Okazaki, Shinichiro Kashiwagi, Hiroaki Tanaka, Kiyoshi Maeda
Article Number: 837
Published online on: 18 October 2021

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Review Open Access

Tertiary lymphoid structure and B‑cell‑related pathways: A potential target in tumor immunotherapy (Review)

Meng Qin, Ying Jin, Ling-Ya Pan
Article Number: 836
Published online on: 18 October 2021

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Article Open Access

Involvement of PBRM1 in VHL disease‑associated clear cell renal cell carcinoma and its putative relationship with the HIF pathway

Sophie Gad, Gwenaël Le Teuff, Baptiste Nguyen, Virginie Verkarre, Veronique Duchatelle, Vincent Molinie, Katia Posseme, Benjamin Grandon, Melanie Da Costa, Bastien Job, Guillaume Meurice, Nathalie Droin, Arnaud Mejean, Sophie Couve, Flore Renaud, Betty Gardie, Bin Tean Teh, Stephane Richard, Sophie Ferlicot
Article Number: 835
Published online on: 15 October 2021

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Review Open Access

Annexin A3 and cancer (Review)

Chao Liu, Nannan Li, Guijian Liu, Xue Feng
Article Number: 834
Published online on: 14 October 2021

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Article Open Access

MicroRNA‑3907 promotes the proliferation and migration of sebaceous gland carcinoma of the eyelid by targeting thrombospondin 1

Chuanli Zhang, Limin Zhu, Xun Liu, Meixia Jiang, Qin Tang, Fei Xu, Tingting Lin, Lijie Dong, Yanjin He
Article Number: 833
Published online on: 14 October 2021

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Article Open Access

Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 832
Published online on: 14 October 2021

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Article Open Access

Ratio of the expression levels of androgen receptor splice variant 7 to androgen receptor in castration refractory prostate cancer

Yoshitaka Sekine, Hiroshi Nakayama, Yoshiyuki Miyazawa, Seiji Arai, Hidekazu Koike, Hiroshi Matsui, Yasuhiro Shibata, Kazuto Ito, Kazuhiro Suzuki
Article Number: 831
Published online on: 13 October 2021

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Article Open Access

Integrated bioinformatics analyses of key genes involved in hepatocellular carcinoma immunosuppression

Hongyan Huang, Youwen Hu, Li Guo, Zhili Wen
Article Number: 830
Published online on: 13 October 2021

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Article Open Access

Role of uromodulin and complement activation in the progression of kidney disease

Fei Shen, Maojing Liu, Fei Pei, Li Yu, Xiangdong Yang
Article Number: 829
Published online on: 13 October 2021

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Article Open Access

Silencing of NACC1 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells via regulating the AKT/mTOR signaling pathway

Zhengyong Cao, Hong Chen, Xiaoli Mei, Xiaobo Li
Article Number: 828
Published online on: 12 October 2021

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Article

Sorafenib treatment of metastatic melanoma with c‑Kit aberration reduces tumor growth and promotes survival

Tomoya Takeda, Masanobu Tsubaki, Natsuki Kato, Shuji Genno, Eri Ichimura, Aya Enomoto, Motohiro Imano, Takao Satou, Shozo Nishida
Article Number: 827
Published online on: 12 October 2021

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Review Open Access

Exosomal circular RNAs: A new frontier in the metastasis of digestive system tumors (Review)

Baile Shen, Keke Sun
Article Number: 826
Published online on: 12 October 2021

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Article Open Access

lncRNA DSCAM‑AS1 facilitates the progression of endometrial cancer via miR‑136‑5p

Luhong Li, Peipei Chen, Bingbing Huang, Peiya Cai
Article Number: 825
Published online on: 12 October 2021

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Article

KLK6 mediates stemness and metabolism of gastric carcinoma cells via the PI3K/AKT/mTOR signaling pathway

Dong Zhou, Yanping He, Hengping Li, Weidong Huang
Article Number: 824
Published online on: 12 October 2021

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Article Open Access

New prognostic factors and scoring system for patients with acute myeloid leukemia

Ye Kuang, Yang Wang, Xianghong Cao, Chuanmei Peng, Hui Gao
Article Number: 823
Published online on: 11 October 2021

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Article Open Access

Aberrant expression of SFRP1, SFRP3, DVL2 and DVL3 Wnt signaling pathway components in diffuse gastric carcinoma

Maja Sremac, Frane Paic, Katja Grubelic Ravic, Ljiljana Serman, Aja Pavicic Dujmovic, Iva Brcic, Zeljko Krznaric, Tamara Nikuseva Martic
Article Number: 822
Published online on: 08 October 2021

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Review Open Access

Pembrolizumab in endometrial cancer: Where we stand now (Review)

Aikaterini Aravantinou‑Fatorou, Angeliki Andrikopoulou, Michael Liontos, Oraianthi Fiste, Vasiliki E. Georgakopoulou, Meletios-Athanasios Dimopoulos, Maria Gavriatopoulou, Flora Zagouri
Article Number: 821
Published online on: 08 October 2021

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Article Open Access

Membranous CD44v6 is upregulated as an early event in colorectal cancer: Downregulation is associated with circulating tumor cells and poor prognosis

Agapi Kataki, Vassilis G. Giannakoulis, Anastasia Derventzi, Konstantinos Papiris, Eythimios Koniaris, Manousos Konstadoulakis
Article Number: 820
Published online on: 08 October 2021

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Article

Exosomal miRNA profiles of triple‑negative breast cancer in neoadjuvant treatment

Aiko Sueta, Yoshitaka Fujiki, Lisa Goto‑Yamaguchi, Mai Tomiguchi, Mutsuko Yamamoto‑Ibusuki, Hirotaka Iwase, Yutaka Yamamoto
Article Number: 819
Published online on: 05 October 2021

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Article Open Access

Long non‑coding RNA SNHG17 promotes lung adenocarcinoma progression by targeting the microRNA‑193a‑5p/NETO2 axis

Zhiwei Zhang, Yulan Yan, Bin Zhang, Yuchen Ma, Chen Chen, Changli Wang
Article Number: 818
Published online on: 05 October 2021

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Review Open Access

Circular RNA regulates the onset and progression of cancer through the mitogen‑activated protein kinase signaling pathway (Review)

Qun Lai, Min Wang, Chunmei Hu, Yan Tang, Yarong Li, Shuhong Hao
Article Number: 817
Published online on: 05 October 2021

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Article Open Access

MicroRNA‑100 inhibits breast cancer cell proliferation, invasion and migration by targeting FOXA1

Haihui Xie, Ruobing Xiao, Yaolin He, Lingzhi He, Changjun Xie, Juan Chen, Yan Hong
Article Number: 816
Published online on: 01 October 2021

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Article Open Access

G2/M cell cycle arrest and apoptosis induced by COH‑203 in human promyelocytic leukemia HL‑60 cells

Jihong Lin, Lei Zhang, Zhiwei Wang, Qi Guan, Kai Bao, Lan Wu
Article Number: 815
Published online on: 28 September 2021

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Article Open Access

Cancer‑associated fibroblast‑secreted collagen triple helix repeat containing‑1 promotes breast cancer cell migration, invasiveness and epithelial‑mesenchymal transition by activating
the Wnt/β‑catenin pathway

Huixin Li, Wei Liu, Xiaoyu Zhang, Yongfeng Wang
Article Number: 814
Published online on: 28 September 2021

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Article

Short 57 kb CDKN2A FISH probe effectively detects short homozygous deletion of the 9p21 locus in malignant pleural mesothelioma

Yuzo Oyama, Makoto Hamasaki, Shinji Matsumoto, Ayuko Sato, Tohru Tsujimura, Kazuki Nabeshima
Article Number: 813
Published online on: 28 September 2021

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Article Open Access

MicroRNA‑23b‑3p targets non‑SMC condensing I complex subunit G to promote proliferation and inhibit apoptosis of colorectal cancer cells via regulation of the PI3K/AKT signaling pathway

Peidong Li, Jing Wen, Xiru Ren, Yu Zhou, Yuan Xue, Zaihua Yan, Shengjie Li, Hongpeng Tian, Xue-Gui Tang, Guang-Jun Zhang
Article Number: 812
Published online on: 28 September 2021

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Review Open Access

Emerging role of BAD and DAD1 as potential targets and biomarkers in cancer (Review)

Yulou Luo, You Wu, Hai Huang, Na Yi, Yan Chen
Article Number: 811
Published online on: 28 September 2021

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Journal Cover
January-2026 Volume 31 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Case Report Open Access

Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Article Open Access

Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Article Open Access

Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Review Open Access

Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Review Open Access

Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Article Open Access

Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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Article Open Access

TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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