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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2015 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Endocrine disruptors and female cancer: Informing the patients (Review)

Lino Del Pup, Alberto Mantovani, Amalia Luce, Carla Cavaliere, Gaetano Facchini, Raffaele Di Francia, Michele Caraglia, Massimiliano Berretta
Pages: 3-11
Published online on: 20 May 2015

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Review

The anticancer effect of Huaier (Review)

Xiaojin Song, Yaming Li, Hanwen Zhang, Qifeng Yang
Pages: 12-21
Published online on: 05 May 2015

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Article Open Access

Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data

Teow Kok-Sin, Norfilza Mohd Mokhtar, Nur Zarina Ali Hassan, Ismail Sagap, Isa Mohamed Rose, Roslan Harun, Rahman Jamal
Pages: 22-32
Published online on: 19 May 2015

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Article Open Access

AMD3100 reduces CXCR4-mediated survival and metastasis of osteosarcoma by inhibiting JNK and Akt, but not p38 or Erk1/2, pathways in in vitro and mouse experiments

Yu-Xin Liao, Ze-Ze Fu, Cheng-Hao Zhou, Lian-Cheng Shan, Zhuo‑Ying Wang, Fei Yin, Long-Po Zheng, Ying-Qi Hua, Zheng-Dong Cai
Pages: 33-42
Published online on: 19 May 2015

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Article Open Access

Nuclear lymphocyte-specific protein tyrosine kinase and its interaction with CR6-interacting factor 1 promote the survival of human leukemic T cells

Shahrooz Vahedi, Fu-Yu Chueh, Sujoy Dutta, Bala Chandran, Chao-Lan Yu
Pages: 43-50
Published online on: 19 May 2015

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Article

miR-139 and miR-200c regulate pancreatic cancer endothelial cell migration and angiogenesis

Lei Li, Baiwen Li, Dafan Chen, Liyan Liu, Chen Huang, Zhanjun Lu, Lungen Lun, Xinjian Wan
Pages: 51-58
Published online on: 04 May 2015

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Article

Effect of sodium/iodide symporter (NIS)-mediated radioiodine therapy on estrogen receptor-negative breast cancer

Chen Yao, Yi Pan, Yongxin Li, Xiangdong Xu, Ying Lin, Wenjian Wang, Shenming Wang
Pages: 59-66
Published online on: 05 May 2015

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Article

Sp1-CD147 positive feedback loop promotes the invasion ability of ovarian cancer Retraction in /10.3892/or.2025.9030

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Pages: 67-76
Published online on: 20 May 2015

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Article

High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer Corrigendum in /10.3892/or.2018.6933 Corrigendum in /10.3892/or.2025.8894

Ping Chen, Deshou Zhao, Weiyi Wang, Yongping Zhang, Yaozong Yuan, Lifu Wang, Yunlin Wu
Pages: 77-86
Published online on: 30 April 2015

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Article

Ski prevents TGF-β-induced EMT and cell invasion by repressing SMAD-dependent signaling in non-small cell lung cancer Corrigendum in /10.3892/or.2020.7868

Haiping Yang, Lei Zhan, Tianjie Yang, Longqiang Wang, Chang Li, Jun Zhao, Zhe Lei, Xiangdong Li, Hong-Tao Zhang
Pages: 87-94
Published online on: 07 May 2015

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Article

Lentiviral-mediated short hairpin RNA silencing of APE1 suppresses hepatocellular carcinoma proliferation and migration: A potential therapeutic target for hepatoma treatment

Zhi-Hua Zheng, Wei Du, Yan-Ju Li, Mei-Qin Gao, Ai-Min Huang, Jing-Feng Liu
Pages: 95-102
Published online on: 13 May 2015

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Article

P2X7 receptor stimulates breast cancer cell invasion and migration via the AKT pathway

Jiyi Xia, Xiaolan Yu, Li Tang, Gang Li, Tao He
Pages: 103-110
Published online on: 13 May 2015

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Article

MicroRNA-153 functions as a tumor suppressor by targeting SET7 and ZEB2 in ovarian cancer cells

Jun Zhou, Ming Xie, Ying Shi, Baihua Luo, Guanghui Gong, Juanni Li, Junpu Wang, Wenjian Zhao, Yuan Zi, Xiaoying Wu, Jifang Wen
Pages: 111-120
Published online on: 05 May 2015

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Article

Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling

Fang Wu, Tianmin Lv, Gang Chen, Huajun Ye, Wei Wu, Gang Li, Fa-Chao Zhi
Pages: 121-128
Published online on: 20 May 2015

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Article

Oncostatin M activates STAT3 to promote endometrial cancer invasion and angiogenesis

Minjiao Zhu, Qi Che, Yun Liao, Huihui Wang, Jingyun Wang, Zheng Chen, Fangyuan Wang, Chenjun Dai, Xiaoping Wan
Pages: 129-138
Published online on: 05 May 2015

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Article

Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis

Mun-Ock Kim, Hyun-Sun Lee, Young-Won Chin, Dong-Oh Moon, Jong-Seog Ahn
Pages: 139-146
Published online on: 05 May 2015

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Article

Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice

Joong Sun Kim, Yeonghoon Son, Min Ji Bae, Minyoung Lee, Chang Geun Lee, Wol Soon Jo, Sung Dae Kim, Kwangmo Yang
Pages: 147-154
Published online on: 13 May 2015

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Article

Prognostic implications of thymidylate synthase gene polymorphisms in patients with advanced small bowel adenocarcinoma treated with first-line fluoropyrimidine-based chemotherapy

Ho-Young Yhim, Sang-Hee Cho, Sam Yong Kim, In Sung Cho, Kyu Taek Lee, Won Sup Lee, Soon Il Lee, Moo Rim Park, Sang-Gon Park, Hye-Suk Han, Yoon Seok Choi, Ik-Joo Chung, Hyun-Jeong Shim, Na-Ri Lee, Eun-Kee Song, Hee Sun Kim, Chang-Yeol Yim
Pages: 155-164
Published online on: 06 May 2015

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Article

Combined expression of ezrin and E-cadherin is associated with lymph node metastasis and poor prognosis in breast cancer

Zhaojin Yu, Mingli Sun, Feng Jin, Qinghuan Xiao, Miao He, Huizhe Wu, Jie Ren, Lin Zhao, Haishan Zhao, Weifan Yao, Fengping Shan, Yaming Cao, Minjie Wei
Pages: 165-174
Published online on: 08 May 2015

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Article

MicroRNA-195-5p acts as an anti-oncogene by targeting PHF19 in hepatocellular carcinoma

Hui Xu, Yan-Wei Hu, Jia-Yi Zhao, Xiu-Mei Hu, Shu-Fen Li, Yan‑Chao Wang, Ji-Juan Gao, Yan-Hua Sha, Chun-Min Kang, Li Lin, Chuan Huang, Jing-Jing Zhao, Lei Zheng, Qian Wang
Pages: 175-182
Published online on: 07 May 2015

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Article

Recombinant hIFN-α2b-BCG inhibits tumor growth in a mouse model of bladder cancer

Erlin Sun, Xiaodong Fan, Lining Wang, Mingde Lei, Xiaodong Zhou, Chunyu Liu, Bingxin Lu, Xuewu Nian, Yan Sun, Ruifa Han
Pages: 183-194
Published online on: 18 May 2015

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Article

P2Y2 nucleotide receptor-mediated extracellular signal-regulated kinases and protein kinase C activation induces the invasion of highly metastatic breast cancer cells

So Young Eun, Young Shin Ko, Sang Won Park, Ki Churl Chang, Hye Jung Kim
Pages: 195-202
Published online on: 11 May 2015

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Article

MicroRNA-377 predicts poor clinical outcome of gastric cancer and induces tumorigenesis by targeting multiple tumor-suppressor genes

Xu Wen, Jian-Qiu Wu, Wei Peng, Ji-Feng Feng, Jin-Hai Tang
Pages: 203-210
Published online on: 15 May 2015

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Article

miR-183 regulates biological behavior in papillary thyroid carcinoma by targeting the programmed cell death 4

Chuankui Wei, Hongming Song, Xiaoguo Sun, Dengfeng Li, Jialu Song, Kaiyao Hua, Lin Fang
Pages: 211-220
Published online on: 11 May 2015

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Article

Ligularia fischeri inhibits endothelial cell proliferation, invasion and tube formation through the inactivation of mitogenic signaling pathways and regulation of vascular endothelial cadherin distribution and matrix metalloproteinase expression

Jae Hyeon Kim, Hyeon-Ju Kim, Jin-Kyu Kim, Eun-Kyung Ahn, Hye-Jin Ko, Young-Rak Cho, Sang-Jin Lee, Gyu-Un Bae, Yong Kee Kim, Jong Woo Park, Joa Sub Oh, Dong-Wan Seo
Pages: 221-226
Published online on: 20 May 2015

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Article

Interference of STAT 5b expression enhances the chemo-sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway-mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Pages: 227-234
Published online on: 19 May 2015

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Article

p62 participates in the inhibition of NF-κB signaling and apoptosis induced by sulfasalazine in human glioma U251 cells

Jing Su, Fei Liu, Meihui Xia, Ye Xu, Xiaoning Li, Jinsong Kang, Yulin Li, Liankun Sun
Pages: 235-243
Published online on: 04 May 2015

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Article

GnRH participates in the self-renewal of A549-derived lung cancer stem-like cells through upregulation of the JNK signaling pathway

Chi Lu, Ting Huang, Weiqun Chen, Hongda Lu
Pages: 244-250
Published online on: 06 May 2015

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Article

Downregulation of MDC1 and 53BP1 by short hairpin RNA enhances radiosensitivity in laryngeal carcinoma cells

Qiheng Gou, Yuxin Xie, Lei Liu, Keqi Xie, Yanxia Wu, Qianqian Wang, Zhu Wang, Ping Li
Pages: 251-257
Published online on: 14 May 2015

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Article

Overexpression of neogenin inhibits cell proliferation and induces apoptosis in human MDA-MB-231 breast carcinoma cells

Qingsong Zhang, Fang Liang, Yang Ke, Yanping Huo, Mingchuang Li, Yanyan Li, Junmin Yue
Pages: 258-264
Published online on: 22 May 2015

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Article

Inhibitory effects of forkhead box L1 gene on osteosarcoma growth through the induction of cell cycle arrest and apoptosis

Xiaodong Chen, Min Deng, Li Ma, Jiansheng Zhou, Yuzhou Xiao, Xinshe Zhou, Changchun Zhang, Min Wu
Pages: 265-271
Published online on: 11 May 2015

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Article

Knockdown of ILK inhibits glioma development via upregulation of E-cadherin and downregulation of cyclin D1

Kebin Zheng, Guangyi Wang, Chunhui Li, Xiaosong Shan, Haipeng Liu
Pages: 272-278
Published online on: 15 May 2015

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Article

Melatonin decreases cell proliferation, impairs myogenic differentiation and triggers apoptotic cell death in rhabdomyosarcoma cell lines

Silvia Codenotti, Michela Battistelli, Sabrina Burattini, Sara Salucci, Elisabetta Falcieri, Rita Rezzani, Fiorella Faggi, Marina Colombi, Eugenio Monti, Alessandro Fanzani
Pages: 279-287
Published online on: 19 May 2015

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Article

MHY-449, a novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, mediates oxidative stress-induced apoptosis in AGS human gastric cancer cells

Seon Hee Kim, Yong Jung Kang, Bokyung Sung, Dong Hwan Kim, Hyun Sook Lim, Hye Rim Kim, Seong Jin Kim, Jeong-Hyun Yoon, Hyung Ryong Moon, Hae Young Chung, Nam Deuk Kim
Pages: 288-294
Published online on: 18 May 2015

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Article

Mutant GNAQ promotes cell viability and migration of uveal melanoma cells through the activation of Notch signaling

Honglei Liu, Chunling Lei, Keqin Long, Xinguang Yang, Zhaoliang Zhu, Lihua Zhang, Jun Liu
Pages: 295-301
Published online on: 05 May 2015

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Article

Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells

Xukui Zhang, Luming Zheng, Yinggang Sun, Tianxiao Wang, Baocheng Wang
Pages: 302-310
Published online on: 15 May 2015

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Article

miR-34a inhibits the migration and invasion of esophageal squamous cell carcinoma by targeting Yin Yang-1

Jihua Nie, Xin Ge, Yangyang Geng, Han Cao, Wei Zhu, Yang Jiao, Jinchang Wu, Jundong Zhou, Jianping Cao
Pages: 311-317
Published online on: 07 May 2015

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Article

Microarray analysis of the aberrant microRNA expression pattern in gliomas of different grades

Xiao-Peng Zhu, Ke-Jie Mou, Qing-Fu Xu, Jun-Hai Tang, Guo-Hao Huang, Jian-Ping Xu, Guang-Hui Li, Si-Jin Ai, Jean-Phillippe Hugnot, Zheng Zhou, Sheng-Qing Lv
Pages: 318-324
Published online on: 06 May 2015

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Article

Integrated analysis of differentially expressed mRNAs and miRNAs between hepatocellular carcinoma and their matched adjacent normal liver tissues

Bing Gao, Shufang Ning, Jilin Li, Haizhou Liu, Wene Wei, Feixiang Wu, Yanping Tang, Yan Feng, Kezhi Li, Litu Zhang
Pages: 325-333
Published online on: 08 May 2015

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Article

M410, a combretastatin A4 analogue, disrupts microtubules and inhibits HIF-1α in human breast cancer cells

Hang Yang, Qing Xia, Yong Zou, Kefeng Wang, Wenqi Jiang, Yuchen Cai
Pages: 334-340
Published online on: 12 May 2015

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Article

RNF8 plays an important role in the radioresistance of human nasopharyngeal cancer cells in vitro

Maoxin Wang, Xianming Chen, Hui Chen, Xian Zhang, Jianzhong Li, Hongxun Gong, Chen Shiyan, Fan Yang
Pages: 341-349
Published online on: 07 May 2015

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Article

Downregulation of CD9 promotes pancreatic cancer growth and metastasis through upregulation of epidermal growth factor on the cell surface

Maochun Tang, Guojian Yin, Feng Wang, Hua Liu, Shu Zhou, Jianbo Ni, Congying Chen, Yingqun Zhou, Yan Zhao
Pages: 350-358
Published online on: 07 May 2015

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Article

Participation of autophagy in the cytotoxicity against breast cancer cells by cisplatin

Meng Shen, Wei-Ming Duan, Meng-Yao Wu, Wen-Jie Wang, Lu Liu, Meng-Dan Xu, Jie Zhu, Dao-Ming Li, Qi Gui, Lian Lian, Fei-Ran Gong, Kai Chen, Wei Li, Min Tao
Pages: 359-367
Published online on: 25 May 2015

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Article

miR-193b acts as a cisplatin sensitizer via the caspase-3-dependent pathway in HCC chemotherapy

Wenjun Yin, Yuehua Nie, Zhiwei Zhang, Liming Xie, Xiusheng He
Pages: 368-374
Published online on: 19 May 2015

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Article

Quercetin-induced autophagy flux enhances TRAIL-mediated tumor cell death

Ji-Hong Moon, Seong Kug Eo, John Hwa Lee, Sang-Youel Park
Pages: 375-381
Published online on: 19 May 2015

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Article

Patterns of radiotherapy practice for pancreatic cancer: Results of the Gastrointestinal Radiation Oncology Study Group multi-institutional survey

Gabriella Macchia, Aldo Sainato, Renato Talamini, Giovanni Boz, Almalina Bacigalupo, Luciana Caravatta, Michele Fiore, Maria Luisa Friso, Vincenzo Fusco, Marco Lupattelli, Giovanna Mantello, Gian Carlo Mattiucci, Najla Slim, Piera Sciacero, Lucia Turri, Vincenzo Valentini, Alessio Giuseppe Morganti, Domenico Genovesi
Pages: 382-390
Published online on: 06 May 2015

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Article

Dissecting the roles of Ephrin-A3 in malignant peripheral nerve sheath tumor by TALENs

Zhengguang Wang, Zhendong Liu, Bo Liu, Gengyan Liu, Song Wu
Pages: 391-398
Published online on: 08 May 2015

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Article

MicroRNA-204 inhibits proliferation, migration, invasion and epithelial-mesenchymal transition in osteosarcoma cells via targeting Sirtuin 1 Retraction in /10.3892/or.2021.8098

Ying Shi, Jianjun Huang, Jun Zhou, Ying Liu, Xiaodan Fu, Yimin Li, Gang Yin, Jifang Wen
Pages: 399-406
Published online on: 19 May 2015

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Article

Antitumor activity of YM155, a selective survivin suppressant, in combination with cisplatin in hepatoblastoma

Ying Yu, Xiaosu Zhao, Yu Zhang, Yanling Kang, Jiaqi Wang, Yingchun Liu
Pages: 407-414
Published online on: 05 May 2015

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Article

Apoptosis inhibitor TRIAP1 is a novel effector of drug resistance

Caroline Adams, Giulia Cazzanelli, Sabeena Rasul, Ben Hitchinson, Yunhui Hu, R. Charles Coombes, Selina Raguz, Ernesto Yagüe
Pages: 415-422
Published online on: 19 May 2015

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Article

RON alternative splicing regulation in primary ovarian cancer

Sebastian Mayer, Marc Hirschfeld, Markus Jaeger, Susanne Pies, Severine Iborra, Thalia Erbes, Elmar Stickeler
Pages: 423-430
Published online on: 19 May 2015

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Article

Delphinidin induces cytotoxicity and potentiates cytocidal effect in combination with arsenite in an acute promyelocytic leukemia NB4 cell line

Bo Yuan, Saki Okusumi, Yuta Yoshino, Chihiro Moriyama, Sachiko Tanaka, Toshihiko Hirano, Norio Takagi, Hiroo Toyoda
Pages: 431-438
Published online on: 08 May 2015

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Article

Krüppel-like factor 4 modulates the migration and invasion of hepatoma cells by suppressing TIMP-1 and TIMP-2

Ming-Ta Sung, Hui-Tzu Hsu, Chih-Chun Lee, Hsin-Chen Lee, Ying‑Ju Kuo, Kate Hua, Cheng-Yuan Hsia, Chin-Wen Chi
Pages: 439-446
Published online on: 08 May 2015

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Article

Endocannabinoid and ceramide levels are altered in patients with colorectal cancer

Ling Chen, Huixia Chen, Yanting Li, Lei Li, Yan Qiu, Jie Ren
Pages: 447-454
Published online on: 12 May 2015

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Article

The histone methyltransferase EZH2 promotes mammary stem and luminal progenitor cell expansion, metastasis and inhibits estrogen receptor-positive cellular differentiation in a model of basal breast cancer

Jianchun Wu, David L. Crowe
Pages: 455-460
Published online on: 21 May 2015

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Article

MicroRNA-370 inhibits the progression of non-small cell lung cancer by downregulating oncogene TRAF4

Tianjun Chen, Fei Gao, Sifang Feng, Tian Yang, Mingwei Chen
Pages: 461-468
Published online on: 13 May 2015

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Article

Targeting of the EGFR/β1 integrin connecting proteins PINCH1 and Nck2 radiosensitizes three-dimensional SCC cell cultures

Lydia Rossow, Iris Eke, Ellen Dickreuter, Nils Cordes
Pages: 469-476
Published online on: 25 May 2015

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Article

The combined use of Camellia sinensis and metronomic zoledronate in 4T1 mouse carcinoma against tumor growth and metastasis

Ke-Wang Luo, Grace Gar-Lee Yue, Chun-Hay Ko, Si Gao, Julia Kin-Ming Lee, Gang Li, Kwok-Pui Fung, Ping-Chung Leung, Clara Bik-San Lau
Pages: 477-487
Published online on: 20 May 2015

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Concentrative nucleoside transporter 3 as a prognostic indicator for favorable outcome of t(8;21)-positive acute myeloid leukemia patients after cytarabine-based chemotherapy

Ju Han Song, Kyung-Min Cho, Hyeoung-Joon Kim, Yeo-Kyeoung Kim, Nan Young Kim, Hee-Je Kim, Tae-Hyang Lee, Seung Yong Hwang, Tae Sung Kim
Pages: 488-494
Published online on: 07 May 2015

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3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation

Khalda Fadlalla, Ramy Elgendy, Ebony Gilbreath, Satyanarayana R. Pondugula, Teshome Yehualaeshet, Mahmoud Mansour, Tesfaye Serbessa, Upender Manne, Temesgen Samuel
Pages: 495-503
Published online on: 11 May 2015

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Gemcitabine treatment enhances HER2 expression in low HER2-expressing breast cancer cells and enhances the antitumor effects of trastuzumab emtansine

Shin Kan, Shigeo Koido, Masato Okamoto, Kazumi Hayashi, Masaki Ito, Yuko Kamata, Hideo Komita, Takefumi Ishidao, Eijiro Nagasaki, Sadamu Homma
Pages: 504-510
Published online on: 12 May 2015

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Daintain/AIF-1 accelerates the activation of insulin-like growth factor-1 receptor signaling pathway in HepG2 cells

Shaohui Jia, Zhongxia Du, Hua Jiang, Xingyuan Huang, Zhengwang Chen, Ning Chen
Pages: 511-517
Published online on: 20 May 2015

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Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells

Dorrah Deeb, Xiaohua Gao, Yongbo Liu, Kirit Pindolia, Subhash C. Gautam
Pages: 518-524
Published online on: 19 May 2015

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miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/β-catenin signaling pathway

Lingqin Song, Di Liu, Baofeng Wang, Jianjun He, Shuqun Zhang, Zhijun Dai, Xiaobin Ma, Xijing Wang
Pages: 525-531
Published online on: 08 May 2015

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Journal Cover
January-2026 Volume 55 Issue 1

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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