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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2015 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Endocrine disruptors and female cancer: Informing the patients (Review)

Lino Del Pup, Alberto Mantovani, Amalia Luce, Carla Cavaliere, Gaetano Facchini, Raffaele Di Francia, Michele Caraglia, Massimiliano Berretta
Pages: 3-11
Published online on: 20 May 2015

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Review

The anticancer effect of Huaier (Review)

Xiaojin Song, Yaming Li, Hanwen Zhang, Qifeng Yang
Pages: 12-21
Published online on: 05 May 2015

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Article Open Access

Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data

Teow Kok-Sin, Norfilza Mohd Mokhtar, Nur Zarina Ali Hassan, Ismail Sagap, Isa Mohamed Rose, Roslan Harun, Rahman Jamal
Pages: 22-32
Published online on: 19 May 2015

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Article Open Access

AMD3100 reduces CXCR4-mediated survival and metastasis of osteosarcoma by inhibiting JNK and Akt, but not p38 or Erk1/2, pathways in in vitro and mouse experiments

Yu-Xin Liao, Ze-Ze Fu, Cheng-Hao Zhou, Lian-Cheng Shan, Zhuo‑Ying Wang, Fei Yin, Long-Po Zheng, Ying-Qi Hua, Zheng-Dong Cai
Pages: 33-42
Published online on: 19 May 2015

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Article Open Access

Nuclear lymphocyte-specific protein tyrosine kinase and its interaction with CR6-interacting factor 1 promote the survival of human leukemic T cells

Shahrooz Vahedi, Fu-Yu Chueh, Sujoy Dutta, Bala Chandran, Chao-Lan Yu
Pages: 43-50
Published online on: 19 May 2015

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Article

miR-139 and miR-200c regulate pancreatic cancer endothelial cell migration and angiogenesis

Lei Li, Baiwen Li, Dafan Chen, Liyan Liu, Chen Huang, Zhanjun Lu, Lungen Lun, Xinjian Wan
Pages: 51-58
Published online on: 04 May 2015

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Article

Effect of sodium/iodide symporter (NIS)-mediated radioiodine therapy on estrogen receptor-negative breast cancer

Chen Yao, Yi Pan, Yongxin Li, Xiangdong Xu, Ying Lin, Wenjian Wang, Shenming Wang
Pages: 59-66
Published online on: 05 May 2015

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Article

Sp1-CD147 positive feedback loop promotes the invasion ability of ovarian cancer Retraction in /10.3892/or.2025.9030

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Pages: 67-76
Published online on: 20 May 2015

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Article

High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer Corrigendum in /10.3892/or.2018.6933 Corrigendum in /10.3892/or.2025.8894

Ping Chen, Deshou Zhao, Weiyi Wang, Yongping Zhang, Yaozong Yuan, Lifu Wang, Yunlin Wu
Pages: 77-86
Published online on: 30 April 2015

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Article

Ski prevents TGF-β-induced EMT and cell invasion by repressing SMAD-dependent signaling in non-small cell lung cancer Corrigendum in /10.3892/or.2020.7868

Haiping Yang, Lei Zhan, Tianjie Yang, Longqiang Wang, Chang Li, Jun Zhao, Zhe Lei, Xiangdong Li, Hong-Tao Zhang
Pages: 87-94
Published online on: 07 May 2015

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Article

Lentiviral-mediated short hairpin RNA silencing of APE1 suppresses hepatocellular carcinoma proliferation and migration: A potential therapeutic target for hepatoma treatment

Zhi-Hua Zheng, Wei Du, Yan-Ju Li, Mei-Qin Gao, Ai-Min Huang, Jing-Feng Liu
Pages: 95-102
Published online on: 13 May 2015

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Article

P2X7 receptor stimulates breast cancer cell invasion and migration via the AKT pathway

Jiyi Xia, Xiaolan Yu, Li Tang, Gang Li, Tao He
Pages: 103-110
Published online on: 13 May 2015

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Article

MicroRNA-153 functions as a tumor suppressor by targeting SET7 and ZEB2 in ovarian cancer cells

Jun Zhou, Ming Xie, Ying Shi, Baihua Luo, Guanghui Gong, Juanni Li, Junpu Wang, Wenjian Zhao, Yuan Zi, Xiaoying Wu, Jifang Wen
Pages: 111-120
Published online on: 05 May 2015

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Article

Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling

Fang Wu, Tianmin Lv, Gang Chen, Huajun Ye, Wei Wu, Gang Li, Fa-Chao Zhi
Pages: 121-128
Published online on: 20 May 2015

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Article

Oncostatin M activates STAT3 to promote endometrial cancer invasion and angiogenesis

Minjiao Zhu, Qi Che, Yun Liao, Huihui Wang, Jingyun Wang, Zheng Chen, Fangyuan Wang, Chenjun Dai, Xiaoping Wan
Pages: 129-138
Published online on: 05 May 2015

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Article

Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis

Mun-Ock Kim, Hyun-Sun Lee, Young-Won Chin, Dong-Oh Moon, Jong-Seog Ahn
Pages: 139-146
Published online on: 05 May 2015

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Article

Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice

Joong Sun Kim, Yeonghoon Son, Min Ji Bae, Minyoung Lee, Chang Geun Lee, Wol Soon Jo, Sung Dae Kim, Kwangmo Yang
Pages: 147-154
Published online on: 13 May 2015

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Article

Prognostic implications of thymidylate synthase gene polymorphisms in patients with advanced small bowel adenocarcinoma treated with first-line fluoropyrimidine-based chemotherapy

Ho-Young Yhim, Sang-Hee Cho, Sam Yong Kim, In Sung Cho, Kyu Taek Lee, Won Sup Lee, Soon Il Lee, Moo Rim Park, Sang-Gon Park, Hye-Suk Han, Yoon Seok Choi, Ik-Joo Chung, Hyun-Jeong Shim, Na-Ri Lee, Eun-Kee Song, Hee Sun Kim, Chang-Yeol Yim
Pages: 155-164
Published online on: 06 May 2015

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Article

Combined expression of ezrin and E-cadherin is associated with lymph node metastasis and poor prognosis in breast cancer

Zhaojin Yu, Mingli Sun, Feng Jin, Qinghuan Xiao, Miao He, Huizhe Wu, Jie Ren, Lin Zhao, Haishan Zhao, Weifan Yao, Fengping Shan, Yaming Cao, Minjie Wei
Pages: 165-174
Published online on: 08 May 2015

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Article

MicroRNA-195-5p acts as an anti-oncogene by targeting PHF19 in hepatocellular carcinoma

Hui Xu, Yan-Wei Hu, Jia-Yi Zhao, Xiu-Mei Hu, Shu-Fen Li, Yan‑Chao Wang, Ji-Juan Gao, Yan-Hua Sha, Chun-Min Kang, Li Lin, Chuan Huang, Jing-Jing Zhao, Lei Zheng, Qian Wang
Pages: 175-182
Published online on: 07 May 2015

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Article

Recombinant hIFN-α2b-BCG inhibits tumor growth in a mouse model of bladder cancer

Erlin Sun, Xiaodong Fan, Lining Wang, Mingde Lei, Xiaodong Zhou, Chunyu Liu, Bingxin Lu, Xuewu Nian, Yan Sun, Ruifa Han
Pages: 183-194
Published online on: 18 May 2015

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Article

P2Y2 nucleotide receptor-mediated extracellular signal-regulated kinases and protein kinase C activation induces the invasion of highly metastatic breast cancer cells

So Young Eun, Young Shin Ko, Sang Won Park, Ki Churl Chang, Hye Jung Kim
Pages: 195-202
Published online on: 11 May 2015

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Article

MicroRNA-377 predicts poor clinical outcome of gastric cancer and induces tumorigenesis by targeting multiple tumor-suppressor genes

Xu Wen, Jian-Qiu Wu, Wei Peng, Ji-Feng Feng, Jin-Hai Tang
Pages: 203-210
Published online on: 15 May 2015

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Article

miR-183 regulates biological behavior in papillary thyroid carcinoma by targeting the programmed cell death 4

Chuankui Wei, Hongming Song, Xiaoguo Sun, Dengfeng Li, Jialu Song, Kaiyao Hua, Lin Fang
Pages: 211-220
Published online on: 11 May 2015

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Article

Ligularia fischeri inhibits endothelial cell proliferation, invasion and tube formation through the inactivation of mitogenic signaling pathways and regulation of vascular endothelial cadherin distribution and matrix metalloproteinase expression

Jae Hyeon Kim, Hyeon-Ju Kim, Jin-Kyu Kim, Eun-Kyung Ahn, Hye-Jin Ko, Young-Rak Cho, Sang-Jin Lee, Gyu-Un Bae, Yong Kee Kim, Jong Woo Park, Joa Sub Oh, Dong-Wan Seo
Pages: 221-226
Published online on: 20 May 2015

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Article

Interference of STAT 5b expression enhances the chemo-sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway-mediated cell apoptosis Expression of Concern in /10.3892/or.2026.9075

Tao Sun, Yanfei Jia, Dongjie Xiao
Pages: 227-234
Published online on: 19 May 2015

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Article

p62 participates in the inhibition of NF-κB signaling and apoptosis induced by sulfasalazine in human glioma U251 cells

Jing Su, Fei Liu, Meihui Xia, Ye Xu, Xiaoning Li, Jinsong Kang, Yulin Li, Liankun Sun
Pages: 235-243
Published online on: 04 May 2015

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Article

GnRH participates in the self-renewal of A549-derived lung cancer stem-like cells through upregulation of the JNK signaling pathway

Chi Lu, Ting Huang, Weiqun Chen, Hongda Lu
Pages: 244-250
Published online on: 06 May 2015

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Article

Downregulation of MDC1 and 53BP1 by short hairpin RNA enhances radiosensitivity in laryngeal carcinoma cells

Qiheng Gou, Yuxin Xie, Lei Liu, Keqi Xie, Yanxia Wu, Qianqian Wang, Zhu Wang, Ping Li
Pages: 251-257
Published online on: 14 May 2015

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Article

Overexpression of neogenin inhibits cell proliferation and induces apoptosis in human MDA-MB-231 breast carcinoma cells

Qingsong Zhang, Fang Liang, Yang Ke, Yanping Huo, Mingchuang Li, Yanyan Li, Junmin Yue
Pages: 258-264
Published online on: 22 May 2015

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Article

Inhibitory effects of forkhead box L1 gene on osteosarcoma growth through the induction of cell cycle arrest and apoptosis

Xiaodong Chen, Min Deng, Li Ma, Jiansheng Zhou, Yuzhou Xiao, Xinshe Zhou, Changchun Zhang, Min Wu
Pages: 265-271
Published online on: 11 May 2015

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Article

Knockdown of ILK inhibits glioma development via upregulation of E-cadherin and downregulation of cyclin D1

Kebin Zheng, Guangyi Wang, Chunhui Li, Xiaosong Shan, Haipeng Liu
Pages: 272-278
Published online on: 15 May 2015

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Article

Melatonin decreases cell proliferation, impairs myogenic differentiation and triggers apoptotic cell death in rhabdomyosarcoma cell lines

Silvia Codenotti, Michela Battistelli, Sabrina Burattini, Sara Salucci, Elisabetta Falcieri, Rita Rezzani, Fiorella Faggi, Marina Colombi, Eugenio Monti, Alessandro Fanzani
Pages: 279-287
Published online on: 19 May 2015

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Article

MHY-449, a novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, mediates oxidative stress-induced apoptosis in AGS human gastric cancer cells

Seon Hee Kim, Yong Jung Kang, Bokyung Sung, Dong Hwan Kim, Hyun Sook Lim, Hye Rim Kim, Seong Jin Kim, Jeong-Hyun Yoon, Hyung Ryong Moon, Hae Young Chung, Nam Deuk Kim
Pages: 288-294
Published online on: 18 May 2015

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Article

Mutant GNAQ promotes cell viability and migration of uveal melanoma cells through the activation of Notch signaling

Honglei Liu, Chunling Lei, Keqin Long, Xinguang Yang, Zhaoliang Zhu, Lihua Zhang, Jun Liu
Pages: 295-301
Published online on: 05 May 2015

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Article

Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells

Xukui Zhang, Luming Zheng, Yinggang Sun, Tianxiao Wang, Baocheng Wang
Pages: 302-310
Published online on: 15 May 2015

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Article

miR-34a inhibits the migration and invasion of esophageal squamous cell carcinoma by targeting Yin Yang-1

Jihua Nie, Xin Ge, Yangyang Geng, Han Cao, Wei Zhu, Yang Jiao, Jinchang Wu, Jundong Zhou, Jianping Cao
Pages: 311-317
Published online on: 07 May 2015

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Article

Microarray analysis of the aberrant microRNA expression pattern in gliomas of different grades

Xiao-Peng Zhu, Ke-Jie Mou, Qing-Fu Xu, Jun-Hai Tang, Guo-Hao Huang, Jian-Ping Xu, Guang-Hui Li, Si-Jin Ai, Jean-Phillippe Hugnot, Zheng Zhou, Sheng-Qing Lv
Pages: 318-324
Published online on: 06 May 2015

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Article

Integrated analysis of differentially expressed mRNAs and miRNAs between hepatocellular carcinoma and their matched adjacent normal liver tissues

Bing Gao, Shufang Ning, Jilin Li, Haizhou Liu, Wene Wei, Feixiang Wu, Yanping Tang, Yan Feng, Kezhi Li, Litu Zhang
Pages: 325-333
Published online on: 08 May 2015

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Article

M410, a combretastatin A4 analogue, disrupts microtubules and inhibits HIF-1α in human breast cancer cells

Hang Yang, Qing Xia, Yong Zou, Kefeng Wang, Wenqi Jiang, Yuchen Cai
Pages: 334-340
Published online on: 12 May 2015

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Article

RNF8 plays an important role in the radioresistance of human nasopharyngeal cancer cells in vitro

Maoxin Wang, Xianming Chen, Hui Chen, Xian Zhang, Jianzhong Li, Hongxun Gong, Chen Shiyan, Fan Yang
Pages: 341-349
Published online on: 07 May 2015

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Article

Downregulation of CD9 promotes pancreatic cancer growth and metastasis through upregulation of epidermal growth factor on the cell surface

Maochun Tang, Guojian Yin, Feng Wang, Hua Liu, Shu Zhou, Jianbo Ni, Congying Chen, Yingqun Zhou, Yan Zhao
Pages: 350-358
Published online on: 07 May 2015

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Article

Participation of autophagy in the cytotoxicity against breast cancer cells by cisplatin

Meng Shen, Wei-Ming Duan, Meng-Yao Wu, Wen-Jie Wang, Lu Liu, Meng-Dan Xu, Jie Zhu, Dao-Ming Li, Qi Gui, Lian Lian, Fei-Ran Gong, Kai Chen, Wei Li, Min Tao
Pages: 359-367
Published online on: 25 May 2015

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Article

miR-193b acts as a cisplatin sensitizer via the caspase-3-dependent pathway in HCC chemotherapy

Wenjun Yin, Yuehua Nie, Zhiwei Zhang, Liming Xie, Xiusheng He
Pages: 368-374
Published online on: 19 May 2015

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Article

Quercetin-induced autophagy flux enhances TRAIL-mediated tumor cell death

Ji-Hong Moon, Seong Kug Eo, John Hwa Lee, Sang-Youel Park
Pages: 375-381
Published online on: 19 May 2015

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Article

Patterns of radiotherapy practice for pancreatic cancer: Results of the Gastrointestinal Radiation Oncology Study Group multi-institutional survey

Gabriella Macchia, Aldo Sainato, Renato Talamini, Giovanni Boz, Almalina Bacigalupo, Luciana Caravatta, Michele Fiore, Maria Luisa Friso, Vincenzo Fusco, Marco Lupattelli, Giovanna Mantello, Gian Carlo Mattiucci, Najla Slim, Piera Sciacero, Lucia Turri, Vincenzo Valentini, Alessio Giuseppe Morganti, Domenico Genovesi
Pages: 382-390
Published online on: 06 May 2015

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Article

Dissecting the roles of Ephrin-A3 in malignant peripheral nerve sheath tumor by TALENs

Zhengguang Wang, Zhendong Liu, Bo Liu, Gengyan Liu, Song Wu
Pages: 391-398
Published online on: 08 May 2015

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Article

MicroRNA-204 inhibits proliferation, migration, invasion and epithelial-mesenchymal transition in osteosarcoma cells via targeting Sirtuin 1 Retraction in /10.3892/or.2021.8098

Ying Shi, Jianjun Huang, Jun Zhou, Ying Liu, Xiaodan Fu, Yimin Li, Gang Yin, Jifang Wen
Pages: 399-406
Published online on: 19 May 2015

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Article

Antitumor activity of YM155, a selective survivin suppressant, in combination with cisplatin in hepatoblastoma

Ying Yu, Xiaosu Zhao, Yu Zhang, Yanling Kang, Jiaqi Wang, Yingchun Liu
Pages: 407-414
Published online on: 05 May 2015

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Article

Apoptosis inhibitor TRIAP1 is a novel effector of drug resistance

Caroline Adams, Giulia Cazzanelli, Sabeena Rasul, Ben Hitchinson, Yunhui Hu, R. Charles Coombes, Selina Raguz, Ernesto Yagüe
Pages: 415-422
Published online on: 19 May 2015

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Article

RON alternative splicing regulation in primary ovarian cancer

Sebastian Mayer, Marc Hirschfeld, Markus Jaeger, Susanne Pies, Severine Iborra, Thalia Erbes, Elmar Stickeler
Pages: 423-430
Published online on: 19 May 2015

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Article

Delphinidin induces cytotoxicity and potentiates cytocidal effect in combination with arsenite in an acute promyelocytic leukemia NB4 cell line

Bo Yuan, Saki Okusumi, Yuta Yoshino, Chihiro Moriyama, Sachiko Tanaka, Toshihiko Hirano, Norio Takagi, Hiroo Toyoda
Pages: 431-438
Published online on: 08 May 2015

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Article

Krüppel-like factor 4 modulates the migration and invasion of hepatoma cells by suppressing TIMP-1 and TIMP-2

Ming-Ta Sung, Hui-Tzu Hsu, Chih-Chun Lee, Hsin-Chen Lee, Ying‑Ju Kuo, Kate Hua, Cheng-Yuan Hsia, Chin-Wen Chi
Pages: 439-446
Published online on: 08 May 2015

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Article

Endocannabinoid and ceramide levels are altered in patients with colorectal cancer

Ling Chen, Huixia Chen, Yanting Li, Lei Li, Yan Qiu, Jie Ren
Pages: 447-454
Published online on: 12 May 2015

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Article

The histone methyltransferase EZH2 promotes mammary stem and luminal progenitor cell expansion, metastasis and inhibits estrogen receptor-positive cellular differentiation in a model of basal breast cancer

Jianchun Wu, David L. Crowe
Pages: 455-460
Published online on: 21 May 2015

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Article

MicroRNA-370 inhibits the progression of non-small cell lung cancer by downregulating oncogene TRAF4

Tianjun Chen, Fei Gao, Sifang Feng, Tian Yang, Mingwei Chen
Pages: 461-468
Published online on: 13 May 2015

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Article

Targeting of the EGFR/β1 integrin connecting proteins PINCH1 and Nck2 radiosensitizes three-dimensional SCC cell cultures

Lydia Rossow, Iris Eke, Ellen Dickreuter, Nils Cordes
Pages: 469-476
Published online on: 25 May 2015

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Article

The combined use of Camellia sinensis and metronomic zoledronate in 4T1 mouse carcinoma against tumor growth and metastasis

Ke-Wang Luo, Grace Gar-Lee Yue, Chun-Hay Ko, Si Gao, Julia Kin-Ming Lee, Gang Li, Kwok-Pui Fung, Ping-Chung Leung, Clara Bik-San Lau
Pages: 477-487
Published online on: 20 May 2015

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Concentrative nucleoside transporter 3 as a prognostic indicator for favorable outcome of t(8;21)-positive acute myeloid leukemia patients after cytarabine-based chemotherapy

Ju Han Song, Kyung-Min Cho, Hyeoung-Joon Kim, Yeo-Kyeoung Kim, Nan Young Kim, Hee-Je Kim, Tae-Hyang Lee, Seung Yong Hwang, Tae Sung Kim
Pages: 488-494
Published online on: 07 May 2015

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3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation

Khalda Fadlalla, Ramy Elgendy, Ebony Gilbreath, Satyanarayana R. Pondugula, Teshome Yehualaeshet, Mahmoud Mansour, Tesfaye Serbessa, Upender Manne, Temesgen Samuel
Pages: 495-503
Published online on: 11 May 2015

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Gemcitabine treatment enhances HER2 expression in low HER2-expressing breast cancer cells and enhances the antitumor effects of trastuzumab emtansine

Shin Kan, Shigeo Koido, Masato Okamoto, Kazumi Hayashi, Masaki Ito, Yuko Kamata, Hideo Komita, Takefumi Ishidao, Eijiro Nagasaki, Sadamu Homma
Pages: 504-510
Published online on: 12 May 2015

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Daintain/AIF-1 accelerates the activation of insulin-like growth factor-1 receptor signaling pathway in HepG2 cells

Shaohui Jia, Zhongxia Du, Hua Jiang, Xingyuan Huang, Zhengwang Chen, Ning Chen
Pages: 511-517
Published online on: 20 May 2015

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Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells

Dorrah Deeb, Xiaohua Gao, Yongbo Liu, Kirit Pindolia, Subhash C. Gautam
Pages: 518-524
Published online on: 19 May 2015

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miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/β-catenin signaling pathway

Lingqin Song, Di Liu, Baofeng Wang, Jianjun He, Shuqun Zhang, Zhijun Dai, Xiaobin Ma, Xijing Wang
Pages: 525-531
Published online on: 08 May 2015

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Journal Cover
April-2026 Volume 55 Issue 4

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells

Natalia Podhorska, Jan Hrabeta, Marie Belhajova, Tomas Eckschlager
Article Number: 79
Published online on: 25 February 2026

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Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer

Alban Piotrowsky, Christian Leischner, Hendrik Schmieder, Katja Detert, Kathrin Schneider, Johanna Schulte, Sabrina Hammerschmidt, Luigi Marongiu, Olga Renner, Markus Burkard, Sascha Venturelli
Article Number: 78
Published online on: 24 February 2026

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Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review)

Zhen Yang, Huajun Liu, Meilin Chen, Liming Zhang, Meiling Gong, Ruilian Yu
Article Number: 77
Published online on: 24 February 2026

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[Retracted] Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma

Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Article Number: 76
Published online on: 24 February 2026

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NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells

Tingyu Zhang, Yue Wang, Jiuna Zhang, Xueshuai Ye, Yanfeng Shen, Zhiwei Zhang
Article Number: 75
Published online on: 18 February 2026

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Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis

Pampana Sandhya Venkata Lakshmi, Jagrati Parashar, Biswajit Biswas, Ramesh Ummanni
Article Number: 74
Published online on: 16 February 2026

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[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9

Zhu Yuan, Andrew J. Sanders, Lin Ye, Yu Wang, Wen G. Jiang
Article Number: 73
Published online on: 16 February 2026

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Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 72
Published online on: 12 February 2026

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Tumor visualization and evaluation of glioblastoma in mice using small animal 9.4T MRI and PET‑CT with high resolution

Shuangyi Li, Wenjiao Gu, Ying Jiang, Ting Liu, Limei Shuai, Yujie Wei, Youming Shi, Havyarimana Juvenal, Zhimin Wang, Yucai Wei, Bofan Wu, Xiaochun Zhou, Yumin Li, Futian Tang
Article Number: 71
Published online on: 12 February 2026

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Expression of Concern Open Access

[Expression of Concern] Interference of STAT 5b expression enhances the chemo‑sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway‑mediated cell apoptosis

Tao Sun, Yanfei Jia, Dongjie Xiao
Article Number: 70
Published online on: 11 February 2026

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Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling

Kun Li, Jinwei Chen, Zhi Zheng, Yichun Gao, Jiayu Zhang, Wenya Ding, Tongguo Yang, Yuyang Gu, Xuhua Duan, Tiesuo Zhao, Huijie Jia, Pengfei Chen, Jianzhuang Ren
Article Number: 69
Published online on: 11 February 2026

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Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma

Mengnan Guo, He Li, Zhifang Zhao, Yuanyuan Wang, Jiaqi Tang, Binghan Zhong, Yunxia Zhao
Article Number: 68
Published online on: 10 February 2026

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[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D

Quanxing Cao, Pingshuan Dong, Yanyu Wang, Junwei Zhang, Xinge Shi, Yongsheng Wang
Article Number: 67
Published online on: 09 February 2026

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Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review)

Han Na Oh, Hoon Hur
Article Number: 66
Published online on: 06 February 2026

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[Corrigendum] Hypoxia and macrophages promote glioblastoma invasion by the CCL4‑CCR5 axis

Ying Wang, Tao Liu, Ning Yang, Shuo Xu, Xingang Li, Donghai Wang
Article Number: 65
Published online on: 04 February 2026

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Origin dictates function: The dual roles of exosomes derived from diverse origins in the onset and progression of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Qingfeng Liu
Article Number: 64
Published online on: 03 February 2026

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Quercetin reduces expression of ATP‑binding cassette transporters by regulating the PTEN/PI3K/AKT signaling pathway in breast cancer cells

Wentao Fu, Leying Lin, Jie Li, Fei Qin, Chuan Chen, Yinglian Cai, Yilun Cai, Yiling Huang, Wang Yang, Shanshan Zhu
Article Number: 63
Published online on: 02 February 2026

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POSTN+ fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling

Chenyang Zhang, Si Chen, Chenghui Qian, Wanqi Lv, Qian Zhang, Yanjin Wang, Yuqiong Wu, Xue Liu
Article Number: 62
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] EGFR/HER2 inhibitors effectively reduce the malignant potential of MDR breast cancer evoked by P‑gp substrates in vitro and in vivo

Yiting Jin, Wei Zhang, Hongying Wang, Zijing Zhang, Chengyu Chu, Xiuping Liu, Qiang Zou
Article Number: 61
Published online on: 02 February 2026

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Tumor‑associated glucocorticoid inhibition by mifepristone reduces polymorphonuclear myeloid‑derived suppressor cells and promotes antitumor immunity in triple‑negative breast cancer‑bearing mice

Masato Kobayashi, Chisana Konno, Ayato Shimizu, Masanori Kobayashi, Tatsuya Hori
Article Number: 60
Published online on: 30 January 2026

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Mitochondria in T‑cell tumor immunity and tumor therapies targeting mitochondria (Review)

Minjie Zhou, Yijie Xie, Zhipeng Liu, Yi He, Yibing Yin, Keyu Chen, Zhengyu Zhao, Chengshun Zhang, Dingjun Cai
Article Number: 59
Published online on: 29 January 2026

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TRIM46 deficiency‑induced DNA damage enhances the sensitivity of cisplatin in non‑small cell lung cancer by regulating the Akt signaling pathway

Song Jin, Dandan Zhang, Zhicheng Liao, Lingpei Yu, Yuanyuan Wang, Pengcheng Jia, Minmin Pan, Yifan Li, Jizhou Zhang
Article Number: 58
Published online on: 28 January 2026

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Advances in isolation and detection technologies and immunotherapy applications of circulating tumor cells (Review)

Ping Zhou, Qin Ye, Yiyun Huang, Yumei Feng, Li Zhou, Ke Xie
Article Number: 57
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] 3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5

Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Article Number: 56
Published online on: 28 January 2026

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High RMI1 expression is associated with cancer cell progression and poor prognosis in prostate cancer

Pengliang Shen, Xiaosong Wang, Xiaoting Yan, Hongyang Du, Bo Wu, Xiaoming Cao
Article Number: 55
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑615‑5p targets insulin‑like growth factor 2 and exerts tumor‑suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Article Number: 54
Published online on: 26 January 2026

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Journal Cover
May-2026 Volume 55 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation

Jessica Nojszewski, Nils Oliver Schröder, Jacqueline Clüver, Jonna Holler, Hajrullah Ahmeti, Michael Synowitz, Janka Held‑Feindt
Article Number: 85
Published online on: 02 March 2026

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[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway 

Sivan M. Bokobza, Lin Ye, Howard G. Kynaston, Wen G. Jiang
Article Number: 84
Published online on: 02 March 2026

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Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest

Minji Bae, Min Kyeong Lee, Mi Gyeong Jeong, Yeonseo Lee, Harim Joo, Young Chan Lee, Jung Woo Lee, Su Il Kim, Seong-Gyu Ko, Young-Gyu Eun
Article Number: 83
Published online on: 27 February 2026

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ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma

Panxin Hu, Anan Li
Article Number: 82
Published online on: 27 February 2026

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Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation

Chao Li, Lei Yang, Yudong Zhang, Baocheng Zhao, Hao Qu
Article Number: 81
Published online on: 25 February 2026

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[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways

Hongxia Zhang, Ruifeng Dong, Ping Zhang, Yankui Wang
Article Number: 80
Published online on: 25 February 2026

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