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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2012 Volume 28 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A multi-centre randomized, open-label phase II trial of continuous erlotinib plus gemcitabine or gemcitabine as first-line therapy in ECOG PS2 patients with advanced non-small cell lung cancer

M. Michael, N. Pavlakis, P. Clingan, R. De Boer, M. Johnston, S. Clarke
Pages: 763-767
Published online on: 15 June 2012

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Article Open Access

Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in human female cancer cell lines

M. Waheed Roomi, Tatiana Kalinovsky, Matthias Rath, Aleksandra Niedzwiecki
Pages: 768-776
Published online on: 20 June 2012

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Article Open Access

Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum

Itasu Ninomiya, Noboru Nagai, Katsunobu Oyama, Hironori Hayashi, Hidehiro Tajima, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tetsuo Ohta
Pages: 777-784
Published online on: 26 June 2012

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Article Open Access

The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model

Christin Geissler, Markus Hambek, Anne Eckardt, Christoph Arnoldner, Marc Diensthuber, Timo Stöver, Jens Wagenblast
Pages: 785-790
Published online on: 06 July 2012

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Article Open Access

Increased E-selectin in hepatic ischemia-reperfusion injury mediates liver metastasis of pancreatic cancer

Katsuhiro Yoshimoto, Hidehiro Tajima, Tetsuo Ohta, Koichi Okamoto, Seisho Sakai, Jun Kinoshita, Hiroyuki Furukawa, Isamu Makino, Hironori Hayashi, Keishi Nakamura, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Hiroshi Itoh, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tomohiko Wakayama, Shoichi Iseki, Koichi Shimizu
Pages: 791-796
Published online on: 03 July 2012

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Article Open Access

Natural chalcones as dual inhibitors of HDACs and NF-κB

B. Orlikova, M. Schnekenburger, M. Zloh, F. Golais, M. Diederich, D. Tasdemir
Pages: 797-805
Published online on: 15 June 2012

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Article

Effect of zinc(II) ions on the expression of pro- and anti-apoptotic factors in high-grade prostate carcinoma cells

Marketa Sztalmachova, Marian Hlavna, Jaromir Gumulec, Monika Holubova, Petr Babula, Jan Balvan, Jiri Sochor, Veronika Tanhauserova, Martina Raudenska, Sona Krizkova, Vojtech Adam, Tomas Eckschlager, Rene Kizek, Michal Masarik
Pages: 806-814
Published online on: 03 July 2012

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Article

Tumor burden in Hodgkin's lymphoma can be reliably estimated from a few staging parameters

Paolo G. Gobbi, Manuela Bergonzi, Emilio Bassi, Francesco Merli, Chiara Coriani, Caterina Stelitano, Emilio Iannitto, Massimo Federico
Pages: 815-820
Published online on: 29 June 2012

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Article

In vivo antitumor effect of liposomes with sialyl Lewis X including monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach

Yoshiyuki Mizushina, Takahiko Hada, Hiromi Yoshida
Pages: 821-828
Published online on: 03 July 2012

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Article

Anti-proliferative effect of an analogue of the LL-37 peptide in the colon cancer derived cell line HCT116 p53+/+ and p53-/-

Kengo Kuroda, Tomokazu Fukuda, Hiroshi Yoneyama, Masafumi Katayama, Hiroshi Isogai, Kazuhiko Okumura, Emiko Isogai
Pages: 829-834
Published online on: 19 June 2012

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Article

Clinical outcome in diffuse large B-cell lymphoma with hepatitis C virus infection in the rituximab era: A single center experience

Hiroki Nishikawa, Mitsuru Tsudo, Yukio Osaki
Pages: 835-840
Published online on: 25 June 2012

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Article

Prediction of invasion depth for submucosal differentiated gastric cancer by magnifying endoscopy with narrow-band imaging

Hideki Kobara, Hirohito Mori, Shintaro Fujihara, Mitsuyoshi Kobayashi, Noriko Nishiyama, Takako Nomura, Kiyohito Kato, Shinichi Ishihara, Toshiaki Morito, Koichi Mizobuchi, Hisakazu Iwama, Tsutomu Masaki
Pages: 841-847
Published online on: 26 June 2012

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Article

Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells

Naomi Miyake, Hiroki Chikumi, Miyako Takata, Masaki Nakamoto, Tadashi Igishi, Eiji Shimizu
Pages: 848-854
Published online on: 12 June 2012

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Article

Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy

Susumu Saigusa, Koji Tanaka, Yuji Toiyama, Kohei Matsushita, Mikio Kawamura, Yoshinaga Okugawa, Junichiro Hiro, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
Pages: 855-861
Published online on: 14 June 2012

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Article

c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells

Keitaro Hayashi, Promsuk Jutabha, Hitoshi Endou, Naohiko Anzai
Pages: 862-866
Published online on: 20 June 2012

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Article

Overexpression of histone deacetylase 6 contributes to accelerated migration and invasion activity of hepatocellular carcinoma cells

Kiminori Kanno, Shoji Kanno, Hiroyuki Nitta, Noriyuki Uesugi, Tamostu  Sugai, Tomoyuki Masuda, Go Wakabayashi, Chihaya Maesawa
Pages: 867-873
Published online on: 04 July 2012

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Article

Downregulation of the Notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor

Liang Zhou, De-Sheng Wang, Qing-Jun Li, Wei Sun, Yong Zhang, Ke-Feng Dou
Pages: 874-882
Published online on: 20 June 2012

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Article

Extracellular protease imaging for cell mass tracking of xenografted human malignant pleural mesothelioma

Lanlan Zhou, Wafik El-Deiry, Wenge Wang, Mary E. Ingram, Sharyn I. Katz
Pages: 883-888
Published online on: 26 June 2012

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Article

Involvement of nuclear NHERF1 in colorectal cancer progression

Anita Mangia, Concetta Saponaro, Andrea Malfettone, Domenico Bisceglie, Antonia Bellizzi, Mariaconsilia Asselti, Ondina Popescu, Stephan J. Reshkin, Angelo Paradiso, Giovanni Simone
Pages: 889-894
Published online on: 03 July 2012

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Article

Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells

Sho Tabata, Ryuji Ikeda, Masatatu Yamamoto, Tatsuhiko Furukawa, Takuya Kuramoto, Yasuo Takeda, Katsushi Yamada, Misako Haraguchi, Yasuhiko Nishioka, Saburo Sone, Shin-Ichi Akiyama
Pages: 895-902
Published online on: 26 June 2012

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Article

Metformin inhibits the development and metastasis of ovarian cancer

Buchu Wu, Shu Li, Lili Sheng, Jing Zhu, Liying Gu, Haoran Shen, Duanduan La, Brett D. Hambly, Shisan Bao, Wen Di
Pages: 903-908
Published online on: 29 June 2012

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Article

Knockdown of CDK6 enhances glioma sensitivity to chemotherapy

Bing Li, Hua He, Bang-Bao Tao, Zhen-Yu Zhao, Guo-Han Hu, Chun Luo, Ju-Xiang Chen, Xue-Hua Ding, Ping Sheng, Yan Dong, Ling Zhang, Yi-Cheng Lu
Pages: 909-914
Published online on: 25 June 2012

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Article

Multiparameter analysis using cell cycle biomarkers for small-size lung adenocarcinoma: prognostic implications

Tomohiro Haruki, Kohei Shomori, Tatsushi Shiomi, Yuji Taniguchi, Hiroshige Nakamura, Hisao Ito
Pages: 915-922
Published online on: 03 July 2012

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Article

Prognostic significance of sirtuin 2 protein nuclear localization in glioma: An immunohistochemical study

Natsuko Imaoka, Masaharu Hiratsuka, Mitsuhiko Osaki, Hideki Kamitani, Atsushi Kambe, Junya Fukuoka, Masanori Kurimoto, Shoichi Nagai, Futoshi Okada, Takashi Watanabe, Eisaku Ohama, Shinsuke Kato, Mitsuo Oshimura
Pages: 923-930
Published online on: 19 June 2012

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Article

Novel function of MKP-5/DUSP10, a phosphatase of stress-activated kinases, on ERK-dependent gene expression, and upregulation of its gene expression in colon carcinomas

Miyuki Nomura, Ken-Ichi Shiiba, Chiaki Katagiri, Isao Kasugai, Kouhei Masuda, Ikuro Sato, Masayuki Sato, Yoichiro Kakugawa, Eiki Nomura, Katsuhisa Hayashi, Yoshihiro Nakamura, Toshiyuki Nagata, Tsunayuki Otsuka, Ryuichi Katakura, Yoji Yamashita, Masami Sato, Nobuhiro Tanuma, Hiroshi Shima
Pages: 931-936
Published online on: 12 June 2012

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Article

VEGF induces angiogenesis in a zebrafish embryo glioma model established by transplantation of human glioma cells

Dong Li, Xiang-Pen Li, Hong-Xuan Wang, Qing-Yu Shen, Xiang-Ping Li, Lu Wen, Xiu-Jiao Qin, Qiu-Li Jia, Hsiang-Fu Kung, Ying Peng
Pages: 937-942
Published online on: 12 June 2012

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Article

PTEN activation sensitizes breast cancer to PI3-kinase inhibitor through the β-catenin signaling pathway

Yu Ren, Xuan Zhou, Yanbin Qi, Guolan Li, Mei Mei, Zhi Yao
Pages: 943-948
Published online on: 12 June 2012

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Article

Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells

Chun-Shu Yu, An-Cheng Huang, Kuang-Chi Lai, Yi-Ping Huang, Meng-Wei Lin, Jai-Sing Yang, Jing-Gung Chung
Pages: 949-954
Published online on: 20 June 2012

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Article

Tetramethylpyrazine-mediated suppression of C6 gliomas involves inhibition of chemokine receptor CXCR4 expression

Keming Yu, Zhao Chen, Xueke Pan, Ying Yang, Sijia Tian, Jing Zhang, Jian Ge, Bala Ambati, Jing Zhuang
Pages: 955-960
Published online on: 14 June 2012

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Article

MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-κB1 pathway

Nannan Liu, Qingmin Sun, Jie Chen, Jiaqi Li, Ying Zeng, Sulan Zhai, Ping Li, Bin Wang, Xuerong Wang
Pages: 961-968
Published online on: 06 July 2012

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Article

Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells

Peixin Sun, Yunhui Liu, Haoqiang Ying, Shaoyi Li
Pages: 969-976
Published online on: 05 July 2012

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Article

The establishment of supramolecular immunobead real-time PCR and the identification of Cox-2 as a metastasis-related marker in colorectal carcinoma

Zu-Guo Li, Xiao-Yan Wang, Jian-Lan Chang, Wei-Bing Xie, Teng-Fei Liu, Qing-Ling Zhang, Yong-Jian Deng, Yan-Qing Ding
Pages: 977-984
Published online on: 15 June 2012

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Article

Lysosomal membrane protein TMEM192 deficiency triggers crosstalk between autophagy and apoptosis in HepG2 hepatoma cells

Zhen Liu, Ya Juan Lv, Yi Peng Song, Xiao Hong Li, Yuan Na Du, Cui Hong Wang, Li Kuan Hu
Pages: 985-991
Published online on: 20 June 2012

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Article

27-hydroxycholesterol and the expression of three estrogen-sensitive proteins in MCF7 cells

Pamela Cruz, María José Epuñán, María Eugenia Ramírez, Cristian G. Torres, Luis E. Valladares, Walter D. Sierralta
Pages: 992-998
Published online on: 12 June 2012

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Article

Inhibitory effect of silibinin on EGFR signal-induced renal cell carcinoma progression via suppression of the EGFR/MMP-9 signaling pathway

Liang Liang, Lei Li, Jin Zeng, Yang Gao, Yu-Le Chen, Zhi-Qiang Wang, Xin-Yang Wang, Luke S. Chang, Dalin He
Pages: 999-1005
Published online on: 19 June 2012

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Article

Effects of PEG-liposomal oxaliplatin on apoptosis, and expression of Cyclin A and Cyclin D1 in colorectal cancer cells

Chuang Yang, Hai-Zhong Liu, Zhong-Xue Fu
Pages: 1006-1012
Published online on: 15 June 2012

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Article

MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1

Yanwei Liu, Wei Yan, Wei Zhang, Lingchao Chen, Gan You, Zhaoshi Bao, Yongzhi Wang, Hongjun Wang, Chunsheng Kang, Tao Jiang
Pages: 1013-1021
Published online on: 05 July 2012

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Article

Klotho inhibits the capacity of cell migration and invasion in cervical cancer

Boogi Chang, Jinsun Kim, Dongjun Jeong, Yujun Jeong, Seob Jeon, Sam-Il Jung, Young Yang, Keun Il Kim, Jong-Seok Lim, Changjin Kim, Myeong-Sok Lee
Pages: 1022-1028
Published online on: 14 June 2012

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Article

Suppression of growth of A549 lung cancer cells by waltonitone and its mechanisms of action

Yi Zhang, Guo-Bin Zhang, Xiao-Man Xu, Meng Zhang, Dan Qu, Hui-Yan Niu, Xue Bai, Liang Kan, Ping He
Pages: 1029-1035
Published online on: 15 June 2012

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Article

Identification of candidate colon cancer biomarkers by applying a random forest approach on microarray data

Zhi Yan, Jiangeng Li, Yimin Xiong, Weitian Xu, Guorong Zheng
Pages: 1036-1042
Published online on: 29 June 2012

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Article

Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells

Dong Yeok Shin, Gi-Young Kim, Chan Gil Kim, Wun-Jae Kim, Ho Sung Kang, Yung Hyun Choi
Pages: 1043-1050
Published online on: 12 June 2012

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Article

Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma

Angelina Di Carlo
Pages: 1051-1056
Published online on: 14 June 2012

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Article

Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect

Sónia Duarte, Agnès Loubat, David Momier, Majlinda Topi, Henrique Faneca, Maria C. Pedroso de Lima, Georges F. Carle, Valérie Pierrefite-Carle
Pages: 1057-1062
Published online on: 06 July 2012

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Article

Anti-proliferative and pro-apoptotic effects of 3,3'-diindolylmethane in human cervical cancer cells

Junyong Zhu, Yuan Li, Chao Guan, Zuhua Chen
Pages: 1063-1068
Published online on: 20 June 2012

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Article

Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer

Wei-Shone Chen, Chung-Man Leung, Hung-Wei Pan, Ling-Yueh Hu, Sung-Chou Li, Meng-Ru Ho, Kuo-Wang Tsai
Pages: 1069-1076
Published online on: 05 July 2012

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Article

Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression

Janine Kah, Andrea Wüstenberg, Amelie Dorothea Keller, Hüseyin Sirma, Roberta Montalbano, Matthias Ocker, Tassilo Volz, Maura Dandri, Gisa Tiegs, Gabriele Sass
Pages: 1077-1083
Published online on: 12 June 2012

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Article

IL-5-induced migration via ERK1/2-mediated MMP-9 expression by inducing activation of NF-κB in HT1376 cells

Eo-Jin Lee, Sung-Soo  Park, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1084-1090
Published online on: 12 June 2012

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Article

Single nucleotide polymorphisms in the regulatory region of gonadotropin-releasing hormone receptor gene and breast cancer susceptibility

Claus Lattrich, Anna-Kristin Müller, Susanne Schüler, Julia Häring, Alexandra Ruoff, Oliver Treeck, Olaf Ortmann
Pages: 1091-1095
Published online on: 12 June 2012

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Article

Anti-inflammatory effects of Calophyllum inophyllum L. in RAW264.7 cells

Shih-Chang Tsai, Yu-Hsin Liang, Jo-Hua Chiang, Fon-Chang Liu, Wen-Hsin Lin, Shu-Jen Chang, Wei-Yu Lin, Chieh-Hsi Wu, Jing-Ru Weng
Pages: 1096-1102
Published online on: 19 June 2012

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Article

The α-iso-cubebenol compound isolated from Schisandra chinensis induces p53-independent pathway-mediated apoptosis in hepatocellular carcinoma cells

Ji Eun Kim, Sun Guen Kim, Jun Sue Goo, Da Jeong Park, You Jin Lee, In Sik Hwang, Hae Ryeon Lee, Sun Il Choi, Young Ju Lee, Chung Hun Oh, Young Whan Choi, Dae Youn Hwang
Pages: 1103-1109
Published online on: 19 June 2012

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Article

Studies on the mechanisms of superagonistic pro-differentiating activities of side-chain modified analogs of vitamin D2

Hanna Baurska, Aleksandra Marchwicka, Anna Kłopot, Andrzej Kutner, Ewa Marcinkowska
Pages: 1110-1116
Published online on: 26 June 2012

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Article

Type III interferon induces apoptosis in human lung cancer cells

Wei Li, Xiaojie Huang, Zhuoming Liu, Yuxuan Wang, Hongwei Zhang, Hongfei Tong, Hao Wu, Shengzhang Lin
Pages: 1117-1125
Published online on: 05 July 2012

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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