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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2012 Volume 28 Issue 3

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A multi-centre randomized, open-label phase II trial of continuous erlotinib plus gemcitabine or gemcitabine as first-line therapy in ECOG PS2 patients with advanced non-small cell lung cancer

M. Michael, N. Pavlakis, P. Clingan, R. De Boer, M. Johnston, S. Clarke
Pages: 763-767
Published online on: 15 June 2012

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Article Open Access

Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in human female cancer cell lines

M. Waheed Roomi, Tatiana Kalinovsky, Matthias Rath, Aleksandra Niedzwiecki
Pages: 768-776
Published online on: 20 June 2012

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Article Open Access

Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum

Itasu Ninomiya, Noboru Nagai, Katsunobu Oyama, Hironori Hayashi, Hidehiro Tajima, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tetsuo Ohta
Pages: 777-784
Published online on: 26 June 2012

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Article Open Access

The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model

Christin Geissler, Markus Hambek, Anne Eckardt, Christoph Arnoldner, Marc Diensthuber, Timo Stöver, Jens Wagenblast
Pages: 785-790
Published online on: 06 July 2012

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Article Open Access

Increased E-selectin in hepatic ischemia-reperfusion injury mediates liver metastasis of pancreatic cancer

Katsuhiro Yoshimoto, Hidehiro Tajima, Tetsuo Ohta, Koichi Okamoto, Seisho Sakai, Jun Kinoshita, Hiroyuki Furukawa, Isamu Makino, Hironori Hayashi, Keishi Nakamura, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Hiroshi Itoh, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tomohiko Wakayama, Shoichi Iseki, Koichi Shimizu
Pages: 791-796
Published online on: 03 July 2012

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Article Open Access

Natural chalcones as dual inhibitors of HDACs and NF-κB

B. Orlikova, M. Schnekenburger, M. Zloh, F. Golais, M. Diederich, D. Tasdemir
Pages: 797-805
Published online on: 15 June 2012

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Article

Effect of zinc(II) ions on the expression of pro- and anti-apoptotic factors in high-grade prostate carcinoma cells

Marketa Sztalmachova, Marian Hlavna, Jaromir Gumulec, Monika Holubova, Petr Babula, Jan Balvan, Jiri Sochor, Veronika Tanhauserova, Martina Raudenska, Sona Krizkova, Vojtech Adam, Tomas Eckschlager, Rene Kizek, Michal Masarik
Pages: 806-814
Published online on: 03 July 2012

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Article

Tumor burden in Hodgkin's lymphoma can be reliably estimated from a few staging parameters

Paolo G. Gobbi, Manuela Bergonzi, Emilio Bassi, Francesco Merli, Chiara Coriani, Caterina Stelitano, Emilio Iannitto, Massimo Federico
Pages: 815-820
Published online on: 29 June 2012

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Article

In vivo antitumor effect of liposomes with sialyl Lewis X including monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach

Yoshiyuki Mizushina, Takahiko Hada, Hiromi Yoshida
Pages: 821-828
Published online on: 03 July 2012

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Article

Anti-proliferative effect of an analogue of the LL-37 peptide in the colon cancer derived cell line HCT116 p53+/+ and p53-/-

Kengo Kuroda, Tomokazu Fukuda, Hiroshi Yoneyama, Masafumi Katayama, Hiroshi Isogai, Kazuhiko Okumura, Emiko Isogai
Pages: 829-834
Published online on: 19 June 2012

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Article

Clinical outcome in diffuse large B-cell lymphoma with hepatitis C virus infection in the rituximab era: A single center experience

Hiroki Nishikawa, Mitsuru Tsudo, Yukio Osaki
Pages: 835-840
Published online on: 25 June 2012

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Article

Prediction of invasion depth for submucosal differentiated gastric cancer by magnifying endoscopy with narrow-band imaging

Hideki Kobara, Hirohito Mori, Shintaro Fujihara, Mitsuyoshi Kobayashi, Noriko Nishiyama, Takako Nomura, Kiyohito Kato, Shinichi Ishihara, Toshiaki Morito, Koichi Mizobuchi, Hisakazu Iwama, Tsutomu Masaki
Pages: 841-847
Published online on: 26 June 2012

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Article

Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells

Naomi Miyake, Hiroki Chikumi, Miyako Takata, Masaki Nakamoto, Tadashi Igishi, Eiji Shimizu
Pages: 848-854
Published online on: 12 June 2012

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Article

Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy

Susumu Saigusa, Koji Tanaka, Yuji Toiyama, Kohei Matsushita, Mikio Kawamura, Yoshinaga Okugawa, Junichiro Hiro, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
Pages: 855-861
Published online on: 14 June 2012

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Article

c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells

Keitaro Hayashi, Promsuk Jutabha, Hitoshi Endou, Naohiko Anzai
Pages: 862-866
Published online on: 20 June 2012

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Article

Overexpression of histone deacetylase 6 contributes to accelerated migration and invasion activity of hepatocellular carcinoma cells

Kiminori Kanno, Shoji Kanno, Hiroyuki Nitta, Noriyuki Uesugi, Tamostu  Sugai, Tomoyuki Masuda, Go Wakabayashi, Chihaya Maesawa
Pages: 867-873
Published online on: 04 July 2012

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Article

Downregulation of the Notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor

Liang Zhou, De-Sheng Wang, Qing-Jun Li, Wei Sun, Yong Zhang, Ke-Feng Dou
Pages: 874-882
Published online on: 20 June 2012

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Article

Extracellular protease imaging for cell mass tracking of xenografted human malignant pleural mesothelioma

Lanlan Zhou, Wafik El-Deiry, Wenge Wang, Mary E. Ingram, Sharyn I. Katz
Pages: 883-888
Published online on: 26 June 2012

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Article

Involvement of nuclear NHERF1 in colorectal cancer progression

Anita Mangia, Concetta Saponaro, Andrea Malfettone, Domenico Bisceglie, Antonia Bellizzi, Mariaconsilia Asselti, Ondina Popescu, Stephan J. Reshkin, Angelo Paradiso, Giovanni Simone
Pages: 889-894
Published online on: 03 July 2012

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Article

Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells

Sho Tabata, Ryuji Ikeda, Masatatu Yamamoto, Tatsuhiko Furukawa, Takuya Kuramoto, Yasuo Takeda, Katsushi Yamada, Misako Haraguchi, Yasuhiko Nishioka, Saburo Sone, Shin-Ichi Akiyama
Pages: 895-902
Published online on: 26 June 2012

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Article

Metformin inhibits the development and metastasis of ovarian cancer

Buchu Wu, Shu Li, Lili Sheng, Jing Zhu, Liying Gu, Haoran Shen, Duanduan La, Brett D. Hambly, Shisan Bao, Wen Di
Pages: 903-908
Published online on: 29 June 2012

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Article

Knockdown of CDK6 enhances glioma sensitivity to chemotherapy

Bing Li, Hua He, Bang-Bao Tao, Zhen-Yu Zhao, Guo-Han Hu, Chun Luo, Ju-Xiang Chen, Xue-Hua Ding, Ping Sheng, Yan Dong, Ling Zhang, Yi-Cheng Lu
Pages: 909-914
Published online on: 25 June 2012

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Article

Multiparameter analysis using cell cycle biomarkers for small-size lung adenocarcinoma: prognostic implications

Tomohiro Haruki, Kohei Shomori, Tatsushi Shiomi, Yuji Taniguchi, Hiroshige Nakamura, Hisao Ito
Pages: 915-922
Published online on: 03 July 2012

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Article

Prognostic significance of sirtuin 2 protein nuclear localization in glioma: An immunohistochemical study

Natsuko Imaoka, Masaharu Hiratsuka, Mitsuhiko Osaki, Hideki Kamitani, Atsushi Kambe, Junya Fukuoka, Masanori Kurimoto, Shoichi Nagai, Futoshi Okada, Takashi Watanabe, Eisaku Ohama, Shinsuke Kato, Mitsuo Oshimura
Pages: 923-930
Published online on: 19 June 2012

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Article

Novel function of MKP-5/DUSP10, a phosphatase of stress-activated kinases, on ERK-dependent gene expression, and upregulation of its gene expression in colon carcinomas

Miyuki Nomura, Ken-Ichi Shiiba, Chiaki Katagiri, Isao Kasugai, Kouhei Masuda, Ikuro Sato, Masayuki Sato, Yoichiro Kakugawa, Eiki Nomura, Katsuhisa Hayashi, Yoshihiro Nakamura, Toshiyuki Nagata, Tsunayuki Otsuka, Ryuichi Katakura, Yoji Yamashita, Masami Sato, Nobuhiro Tanuma, Hiroshi Shima
Pages: 931-936
Published online on: 12 June 2012

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Article

VEGF induces angiogenesis in a zebrafish embryo glioma model established by transplantation of human glioma cells

Dong Li, Xiang-Pen Li, Hong-Xuan Wang, Qing-Yu Shen, Xiang-Ping Li, Lu Wen, Xiu-Jiao Qin, Qiu-Li Jia, Hsiang-Fu Kung, Ying Peng
Pages: 937-942
Published online on: 12 June 2012

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Article

PTEN activation sensitizes breast cancer to PI3-kinase inhibitor through the β-catenin signaling pathway

Yu Ren, Xuan Zhou, Yanbin Qi, Guolan Li, Mei Mei, Zhi Yao
Pages: 943-948
Published online on: 12 June 2012

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Article

Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells

Chun-Shu Yu, An-Cheng Huang, Kuang-Chi Lai, Yi-Ping Huang, Meng-Wei Lin, Jai-Sing Yang, Jing-Gung Chung
Pages: 949-954
Published online on: 20 June 2012

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Article

Tetramethylpyrazine-mediated suppression of C6 gliomas involves inhibition of chemokine receptor CXCR4 expression

Keming Yu, Zhao Chen, Xueke Pan, Ying Yang, Sijia Tian, Jing Zhang, Jian Ge, Bala Ambati, Jing Zhuang
Pages: 955-960
Published online on: 14 June 2012

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Article

MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-κB1 pathway

Nannan Liu, Qingmin Sun, Jie Chen, Jiaqi Li, Ying Zeng, Sulan Zhai, Ping Li, Bin Wang, Xuerong Wang
Pages: 961-968
Published online on: 06 July 2012

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Article

Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells

Peixin Sun, Yunhui Liu, Haoqiang Ying, Shaoyi Li
Pages: 969-976
Published online on: 05 July 2012

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Article

The establishment of supramolecular immunobead real-time PCR and the identification of Cox-2 as a metastasis-related marker in colorectal carcinoma

Zu-Guo Li, Xiao-Yan Wang, Jian-Lan Chang, Wei-Bing Xie, Teng-Fei Liu, Qing-Ling Zhang, Yong-Jian Deng, Yan-Qing Ding
Pages: 977-984
Published online on: 15 June 2012

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Article

Lysosomal membrane protein TMEM192 deficiency triggers crosstalk between autophagy and apoptosis in HepG2 hepatoma cells

Zhen Liu, Ya Juan Lv, Yi Peng Song, Xiao Hong Li, Yuan Na Du, Cui Hong Wang, Li Kuan Hu
Pages: 985-991
Published online on: 20 June 2012

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Article

27-hydroxycholesterol and the expression of three estrogen-sensitive proteins in MCF7 cells

Pamela Cruz, María José Epuñán, María Eugenia Ramírez, Cristian G. Torres, Luis E. Valladares, Walter D. Sierralta
Pages: 992-998
Published online on: 12 June 2012

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Article

Inhibitory effect of silibinin on EGFR signal-induced renal cell carcinoma progression via suppression of the EGFR/MMP-9 signaling pathway

Liang Liang, Lei Li, Jin Zeng, Yang Gao, Yu-Le Chen, Zhi-Qiang Wang, Xin-Yang Wang, Luke S. Chang, Dalin He
Pages: 999-1005
Published online on: 19 June 2012

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Article

Effects of PEG-liposomal oxaliplatin on apoptosis, and expression of Cyclin A and Cyclin D1 in colorectal cancer cells

Chuang Yang, Hai-Zhong Liu, Zhong-Xue Fu
Pages: 1006-1012
Published online on: 15 June 2012

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Article

MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1

Yanwei Liu, Wei Yan, Wei Zhang, Lingchao Chen, Gan You, Zhaoshi Bao, Yongzhi Wang, Hongjun Wang, Chunsheng Kang, Tao Jiang
Pages: 1013-1021
Published online on: 05 July 2012

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Article

Klotho inhibits the capacity of cell migration and invasion in cervical cancer

Boogi Chang, Jinsun Kim, Dongjun Jeong, Yujun Jeong, Seob Jeon, Sam-Il Jung, Young Yang, Keun Il Kim, Jong-Seok Lim, Changjin Kim, Myeong-Sok Lee
Pages: 1022-1028
Published online on: 14 June 2012

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Article

Suppression of growth of A549 lung cancer cells by waltonitone and its mechanisms of action

Yi Zhang, Guo-Bin Zhang, Xiao-Man Xu, Meng Zhang, Dan Qu, Hui-Yan Niu, Xue Bai, Liang Kan, Ping He
Pages: 1029-1035
Published online on: 15 June 2012

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Article

Identification of candidate colon cancer biomarkers by applying a random forest approach on microarray data

Zhi Yan, Jiangeng Li, Yimin Xiong, Weitian Xu, Guorong Zheng
Pages: 1036-1042
Published online on: 29 June 2012

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Article

Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells

Dong Yeok Shin, Gi-Young Kim, Chan Gil Kim, Wun-Jae Kim, Ho Sung Kang, Yung Hyun Choi
Pages: 1043-1050
Published online on: 12 June 2012

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Article

Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma

Angelina Di Carlo
Pages: 1051-1056
Published online on: 14 June 2012

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Article

Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect

Sónia Duarte, Agnès Loubat, David Momier, Majlinda Topi, Henrique Faneca, Maria C. Pedroso de Lima, Georges F. Carle, Valérie Pierrefite-Carle
Pages: 1057-1062
Published online on: 06 July 2012

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Article

Anti-proliferative and pro-apoptotic effects of 3,3'-diindolylmethane in human cervical cancer cells

Junyong Zhu, Yuan Li, Chao Guan, Zuhua Chen
Pages: 1063-1068
Published online on: 20 June 2012

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Article

Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer

Wei-Shone Chen, Chung-Man Leung, Hung-Wei Pan, Ling-Yueh Hu, Sung-Chou Li, Meng-Ru Ho, Kuo-Wang Tsai
Pages: 1069-1076
Published online on: 05 July 2012

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Article

Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression

Janine Kah, Andrea Wüstenberg, Amelie Dorothea Keller, Hüseyin Sirma, Roberta Montalbano, Matthias Ocker, Tassilo Volz, Maura Dandri, Gisa Tiegs, Gabriele Sass
Pages: 1077-1083
Published online on: 12 June 2012

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Article

IL-5-induced migration via ERK1/2-mediated MMP-9 expression by inducing activation of NF-κB in HT1376 cells

Eo-Jin Lee, Sung-Soo  Park, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1084-1090
Published online on: 12 June 2012

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Article

Single nucleotide polymorphisms in the regulatory region of gonadotropin-releasing hormone receptor gene and breast cancer susceptibility

Claus Lattrich, Anna-Kristin Müller, Susanne Schüler, Julia Häring, Alexandra Ruoff, Oliver Treeck, Olaf Ortmann
Pages: 1091-1095
Published online on: 12 June 2012

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Article

Anti-inflammatory effects of Calophyllum inophyllum L. in RAW264.7 cells

Shih-Chang Tsai, Yu-Hsin Liang, Jo-Hua Chiang, Fon-Chang Liu, Wen-Hsin Lin, Shu-Jen Chang, Wei-Yu Lin, Chieh-Hsi Wu, Jing-Ru Weng
Pages: 1096-1102
Published online on: 19 June 2012

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Article

The α-iso-cubebenol compound isolated from Schisandra chinensis induces p53-independent pathway-mediated apoptosis in hepatocellular carcinoma cells

Ji Eun Kim, Sun Guen Kim, Jun Sue Goo, Da Jeong Park, You Jin Lee, In Sik Hwang, Hae Ryeon Lee, Sun Il Choi, Young Ju Lee, Chung Hun Oh, Young Whan Choi, Dae Youn Hwang
Pages: 1103-1109
Published online on: 19 June 2012

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Article

Studies on the mechanisms of superagonistic pro-differentiating activities of side-chain modified analogs of vitamin D2

Hanna Baurska, Aleksandra Marchwicka, Anna Kłopot, Andrzej Kutner, Ewa Marcinkowska
Pages: 1110-1116
Published online on: 26 June 2012

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Article

Type III interferon induces apoptosis in human lung cancer cells

Wei Li, Xiaojie Huang, Zhuoming Liu, Yuxuan Wang, Hongwei Zhang, Hongfei Tong, Hao Wu, Shengzhang Lin
Pages: 1117-1125
Published online on: 05 July 2012

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Journal Cover
October-2026 Volume 56 Issue 4

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Genomic instability, postoperative recurrence and therapeutic vulnerabilities in resectable non‑small cell lung cancer (Review)

Linlin Wang, Yong Feng, Qiang Liu
Article Number: 182
Published online on: 28 August 2026

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Review Open Access

Research progress on lactate metabolism in lung cancer: Tumorigenesis, drug resistance and clinical translation (Review)

Yuantao Zhang, Yiyang Shang, Hai Zeng, Ruiling Ning, Xinran Zhang, Dongxu Ao, Jun Cai, Qingqing Ye
Article Number: 181
Published online on: 28 August 2026

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Review Open Access

Decoding the metabolic‑immune crosstalk: The role of glutamine and ammonium reprogramming in prostate cancer immune evasion (Review)

Peilong Wang, Xiaoran Li, Teng Ma, Jun Mi
Article Number: 180
Published online on: 27 August 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells

Jing Guo, Li Chen, Ning Luo, Weihong Yang, Xiaoyan Qu, Zhongping Cheng
Article Number: 179
Published online on: 24 August 2026

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Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism

Xinhe Bai, Yongfeng Yang, Yuling Luo, Pei Jing, Xia Hong, Yaqin Zou, Yan Dai, Xuping Yang, Meiling Zhou, Han Xiao, Yilan Huang, Shiwei Guo, Qingze Fan
Article Number: 178
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Targeting ribonucleotide reductase M2 subunit by small interfering RNA exerts anti‑oncogenic effects in gastric adenocarcinoma 

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Junhong Zhao, Shiyan Wang, Yujuan Dong, Frankie M.C. Sin, Saifung Yeung, Alfred S.L. Cheng, Jun Yu, Kafai To
Article Number: 177
Published online on: 20 August 2026

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Cancer‑associated fibroblast‑derived extracellular vesicles promote pancreatic cancer progression via the RAP1B/ANLN axis

Daigo Yoshimori, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Akira Matsushita, Youichi Kawano, Takashi Ono, Takahiro Haruna, Kazuhiko Endo, Akira Hamaguchi, Takenori Fujii, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, Atsushi Masamune, Akihisa Matsuda, Hiroshi Yoshida, Ryuji Ohashi
Article Number: 176
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Restoration of the tumor‑suppressor function to mutant p53 by Ganoderma lucidum polysaccharides in colorectal cancer cells

Dan Jiang, Lingyao Wang, Tong Zhao, Zhaoyu Zhang, Renxia Zhang, Jingji Jin, Yong Cai, Fei Wang
Article Number: 175
Published online on: 17 August 2026

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Molecular classification and precision therapy in gastric cancer: Current advances and future perspectives (Review)

Shujing Xia, Xiumei Zhang, Lizhong Tang, Anqi Li, Jianhai Chen, Zhang Tao
Article Number: 174
Published online on: 14 August 2026

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Expression of Concern Open Access

[Expression of Concern] Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways

Zhenhua Yang, Ying Liu, Changzheng Shi, Yuqin Zhang, Rongzhao Lv, Rong Zhang, Qian Wang, Yiming Wang
Article Number: 173
Published online on: 12 August 2026

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Article Open Access

OLR1 promotes cell proliferation and invasion while represses apoptosis via regulating histone H3 lysine 18 lactylation‑mediated LEMD1 in papillary thyroid cancer

Jiawei Yu, Rui Pang, Bo Liu, Lili Chen, Jiewu Zhang
Article Number: 172
Published online on: 11 August 2026

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Correction Open Access

[Corrigendum] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 171
Published online on: 10 August 2026

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Review Open Access

Polyphenol‑based interventions in breast cancer: Signaling pathways, molecular mechanisms and translational therapeutic strategies (Review)

Jingjing Zeng, Jinyan Hu, Zhiyuan Ma, Suansuan Zhu, Xiangling Lv, Lanhai Zhang, Mimi Shen, Taolang Li
Article Number: 170
Published online on: 07 August 2026

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Article Open Access

HDAC1 promotes lung adenocarcinoma progression via the nuclear accumulation of β‑catenin

Shijie Xu, Xiaolu Chang, Xiayu Wu, Fabao Wang, Jing Xiang, Chaoxiang Lin, He Zhao, Junzhe Li, Xianhua Xu
Article Number: 169
Published online on: 07 August 2026

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Retraction Open Access

[Retracted] MicroRNA‑365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3

Yonggang Zhu, Hongguang Zhao, Min Rao, Songbai Xu
Article Number: 168
Published online on: 27 July 2026

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Review Open Access

CTGF: The remodeler of the tumor immune microenvironment (Review)

Ying Zhao, Li Han, Qingyu Wu, Haiying Li, Fuhong Dai
Article Number: 167
Published online on: 24 July 2026

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Article Open Access

Anticancer effects of tangeretin associated with reactive oxygen species generation, mitochondrial dysfunction and apoptosis in CaSki cells

Seung-Hyeon Ahn, Zeeshan Ahmad Bhutta, Hwayoung Na, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 166
Published online on: 24 July 2026

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Article Open Access

Stable overexpression of Nup88 enhances HeLa cell migration through independent regulation of Kif7 and Gli1

Masaki Makise, Ryota Uchimura, Ayano Shiraishi, Akihiko Kuniyasu
Article Number: 165
Published online on: 24 July 2026

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Article

TPD54 contributes to docetaxel resistance through modulation of P‑glycoprotein localization and activity in oral squamous cell carcinoma cells

Maki Nara, Yoshiki Mukudai, Masataka Watanabe, Nodoka Kindaichi, Konomi Yamada, Yuzo Abe, Toshikazu Shimane, Tatsuo Shirota, Seigo Ohba
Article Number: 164
Published online on: 24 July 2026

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November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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