Journal Articles
Article
A multi-centre randomized, open-label phase II trial of continuous erlotinib plus gemcitabine or gemcitabine as first-line therapy in ECOG PS2 patients with advanced non-small cell lung cancer
M. Michael, N. Pavlakis, P. Clingan, R. De Boer, M. Johnston, S. Clarke
Pages: 763-767 Published online on: 15 June 2012
Article
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in human female cancer cell lines
M. Waheed Roomi, Tatiana Kalinovsky, Matthias Rath, Aleksandra Niedzwiecki
Pages: 768-776 Published online on: 20 June 2012
Article
Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum
Itasu Ninomiya, Noboru Nagai, Katsunobu Oyama, Hironori Hayashi, Hidehiro Tajima, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tetsuo Ohta
Pages: 777-784 Published online on: 26 June 2012
Article
The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model
Christin Geissler, Markus Hambek, Anne Eckardt, Christoph Arnoldner, Marc Diensthuber, Timo Stöver, Jens Wagenblast
Pages: 785-790 Published online on: 06 July 2012
Article
Increased E-selectin in hepatic ischemia-reperfusion injury mediates liver metastasis of pancreatic cancer
Katsuhiro Yoshimoto, Hidehiro Tajima, Tetsuo Ohta, Koichi Okamoto, Seisho Sakai, Jun Kinoshita, Hiroyuki Furukawa, Isamu Makino, Hironori Hayashi, Keishi Nakamura, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Hiroshi Itoh, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Tomohiko Wakayama, Shoichi Iseki, Koichi Shimizu
Pages: 791-796 Published online on: 03 July 2012
Article
Natural chalcones as dual inhibitors of HDACs and NF-κB
B. Orlikova, M. Schnekenburger, M. Zloh, F. Golais, M. Diederich, D. Tasdemir
Pages: 797-805 Published online on: 15 June 2012
Article
Effect of zinc(II) ions on the expression of pro- and anti-apoptotic factors in high-grade prostate carcinoma cells
Marketa Sztalmachova, Marian Hlavna, Jaromir Gumulec, Monika Holubova, Petr Babula, Jan Balvan, Jiri Sochor, Veronika Tanhauserova, Martina Raudenska, Sona Krizkova, Vojtech Adam, Tomas Eckschlager, Rene Kizek, Michal Masarik
Pages: 806-814 Published online on: 03 July 2012
Article
Tumor burden in Hodgkin's lymphoma can be reliably estimated from a few staging parameters
Paolo G. Gobbi, Manuela Bergonzi, Emilio Bassi, Francesco Merli, Chiara Coriani, Caterina Stelitano, Emilio Iannitto, Massimo Federico
Pages: 815-820 Published online on: 29 June 2012
Article
In vivo antitumor effect of liposomes with sialyl Lewis X including monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach
Yoshiyuki Mizushina, Takahiko Hada, Hiromi Yoshida
Pages: 821-828 Published online on: 03 July 2012
Article
Anti-proliferative effect of an analogue of the LL-37 peptide in the colon cancer derived cell line HCT116 p53+/+ and p53-/-
Kengo Kuroda, Tomokazu Fukuda, Hiroshi Yoneyama, Masafumi Katayama, Hiroshi Isogai, Kazuhiko Okumura, Emiko Isogai
Pages: 829-834 Published online on: 19 June 2012
Article
Clinical outcome in diffuse large B-cell lymphoma with hepatitis C virus infection in the rituximab era: A single center experience
Hiroki Nishikawa, Mitsuru Tsudo, Yukio Osaki
Pages: 835-840 Published online on: 25 June 2012
Article
Prediction of invasion depth for submucosal differentiated gastric cancer by magnifying endoscopy with narrow-band imaging
Hideki Kobara, Hirohito Mori, Shintaro Fujihara, Mitsuyoshi Kobayashi, Noriko Nishiyama, Takako Nomura, Kiyohito Kato, Shinichi Ishihara, Toshiaki Morito, Koichi Mizobuchi, Hisakazu Iwama, Tsutomu Masaki
Pages: 841-847 Published online on: 26 June 2012
Article
Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells
Naomi Miyake, Hiroki Chikumi, Miyako Takata, Masaki Nakamoto, Tadashi Igishi, Eiji Shimizu
Pages: 848-854 Published online on: 12 June 2012
Article
Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy
Susumu Saigusa, Koji Tanaka, Yuji Toiyama, Kohei Matsushita, Mikio Kawamura, Yoshinaga Okugawa, Junichiro Hiro, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
Pages: 855-861 Published online on: 14 June 2012
Article
c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells
Keitaro Hayashi, Promsuk Jutabha, Hitoshi Endou, Naohiko Anzai
Pages: 862-866 Published online on: 20 June 2012
Article
Overexpression of histone deacetylase 6 contributes to accelerated migration and invasion activity of hepatocellular carcinoma cells
Kiminori Kanno, Shoji Kanno, Hiroyuki Nitta, Noriyuki Uesugi, Tamostu Sugai, Tomoyuki Masuda, Go Wakabayashi, Chihaya Maesawa
Pages: 867-873 Published online on: 04 July 2012
Article
Downregulation of the Notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor
Liang Zhou, De-Sheng Wang, Qing-Jun Li, Wei Sun, Yong Zhang, Ke-Feng Dou
Pages: 874-882 Published online on: 20 June 2012
Article
Extracellular protease imaging for cell mass tracking of xenografted human malignant pleural mesothelioma
Lanlan Zhou, Wafik El-Deiry, Wenge Wang, Mary E. Ingram, Sharyn I. Katz
Pages: 883-888 Published online on: 26 June 2012
Article
Involvement of nuclear NHERF1 in colorectal cancer progression
Anita Mangia, Concetta Saponaro, Andrea Malfettone, Domenico Bisceglie, Antonia Bellizzi, Mariaconsilia Asselti, Ondina Popescu, Stephan J. Reshkin, Angelo Paradiso, Giovanni Simone
Pages: 889-894 Published online on: 03 July 2012
Article
Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells
Sho Tabata, Ryuji Ikeda, Masatatu Yamamoto, Tatsuhiko Furukawa, Takuya Kuramoto, Yasuo Takeda, Katsushi Yamada, Misako Haraguchi, Yasuhiko Nishioka, Saburo Sone, Shin-Ichi Akiyama
Pages: 895-902 Published online on: 26 June 2012
Article
Metformin inhibits the development and metastasis of ovarian cancer
Buchu Wu, Shu Li, Lili Sheng, Jing Zhu, Liying Gu, Haoran Shen, Duanduan La, Brett D. Hambly, Shisan Bao, Wen Di
Pages: 903-908 Published online on: 29 June 2012
Article
Knockdown of CDK6 enhances glioma sensitivity to chemotherapy
Bing Li, Hua He, Bang-Bao Tao, Zhen-Yu Zhao, Guo-Han Hu, Chun Luo, Ju-Xiang Chen, Xue-Hua Ding, Ping Sheng, Yan Dong, Ling Zhang, Yi-Cheng Lu
Pages: 909-914 Published online on: 25 June 2012
Article
Multiparameter analysis using cell cycle biomarkers for small-size lung adenocarcinoma: prognostic implications
Tomohiro Haruki, Kohei Shomori, Tatsushi Shiomi, Yuji Taniguchi, Hiroshige Nakamura, Hisao Ito
Pages: 915-922 Published online on: 03 July 2012
Article
Prognostic significance of sirtuin 2 protein nuclear localization in glioma: An immunohistochemical study
Natsuko Imaoka, Masaharu Hiratsuka, Mitsuhiko Osaki, Hideki Kamitani, Atsushi Kambe, Junya Fukuoka, Masanori Kurimoto, Shoichi Nagai, Futoshi Okada, Takashi Watanabe, Eisaku Ohama, Shinsuke Kato, Mitsuo Oshimura
Pages: 923-930 Published online on: 19 June 2012
Article
Novel function of MKP-5/DUSP10, a phosphatase of stress-activated kinases, on ERK-dependent gene expression, and upregulation of its gene expression in colon carcinomas
Miyuki Nomura, Ken-Ichi Shiiba, Chiaki Katagiri, Isao Kasugai, Kouhei Masuda, Ikuro Sato, Masayuki Sato, Yoichiro Kakugawa, Eiki Nomura, Katsuhisa Hayashi, Yoshihiro Nakamura, Toshiyuki Nagata, Tsunayuki Otsuka, Ryuichi Katakura, Yoji Yamashita, Masami Sato, Nobuhiro Tanuma, Hiroshi Shima
Pages: 931-936 Published online on: 12 June 2012
Article
VEGF induces angiogenesis in a zebrafish embryo glioma model established by transplantation of human glioma cells
Dong Li, Xiang-Pen Li, Hong-Xuan Wang, Qing-Yu Shen, Xiang-Ping Li, Lu Wen, Xiu-Jiao Qin, Qiu-Li Jia, Hsiang-Fu Kung, Ying Peng
Pages: 937-942 Published online on: 12 June 2012
Article
PTEN activation sensitizes breast cancer to PI3-kinase inhibitor through the β-catenin signaling pathway
Yu Ren, Xuan Zhou, Yanbin Qi, Guolan Li, Mei Mei, Zhi Yao
Pages: 943-948 Published online on: 12 June 2012
Article
Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells
Chun-Shu Yu, An-Cheng Huang, Kuang-Chi Lai, Yi-Ping Huang, Meng-Wei Lin, Jai-Sing Yang, Jing-Gung Chung
Pages: 949-954 Published online on: 20 June 2012
Article
Tetramethylpyrazine-mediated suppression of C6 gliomas involves inhibition of chemokine receptor CXCR4 expression
Keming Yu, Zhao Chen, Xueke Pan, Ying Yang, Sijia Tian, Jing Zhang, Jian Ge, Bala Ambati, Jing Zhuang
Pages: 955-960 Published online on: 14 June 2012
Article
MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-κB1 pathway
Nannan Liu, Qingmin Sun, Jie Chen, Jiaqi Li, Ying Zeng, Sulan Zhai, Ping Li, Bin Wang, Xuerong Wang
Pages: 961-968 Published online on: 06 July 2012
Article
Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells
Peixin Sun, Yunhui Liu, Haoqiang Ying, Shaoyi Li
Pages: 969-976 Published online on: 05 July 2012
Article
The establishment of supramolecular immunobead real-time PCR and the identification of Cox-2 as a metastasis-related marker in colorectal carcinoma
Zu-Guo Li, Xiao-Yan Wang, Jian-Lan Chang, Wei-Bing Xie, Teng-Fei Liu, Qing-Ling Zhang, Yong-Jian Deng, Yan-Qing Ding
Pages: 977-984 Published online on: 15 June 2012
Article
Lysosomal membrane protein TMEM192 deficiency triggers crosstalk between autophagy and apoptosis in HepG2 hepatoma cells
Zhen Liu, Ya Juan Lv, Yi Peng Song, Xiao Hong Li, Yuan Na Du, Cui Hong Wang, Li Kuan Hu
Pages: 985-991 Published online on: 20 June 2012
Article
27-hydroxycholesterol and the expression of three estrogen-sensitive proteins in MCF7 cells
Pamela Cruz, María José Epuñán, María Eugenia Ramírez, Cristian G. Torres, Luis E. Valladares, Walter D. Sierralta
Pages: 992-998 Published online on: 12 June 2012
Article
Inhibitory effect of silibinin on EGFR signal-induced renal cell carcinoma progression via suppression of the EGFR/MMP-9 signaling pathway
Liang Liang, Lei Li, Jin Zeng, Yang Gao, Yu-Le Chen, Zhi-Qiang Wang, Xin-Yang Wang, Luke S. Chang, Dalin He
Pages: 999-1005 Published online on: 19 June 2012
Article
Effects of PEG-liposomal oxaliplatin on apoptosis, and expression of Cyclin A and Cyclin D1 in colorectal cancer cells
Chuang Yang, Hai-Zhong Liu, Zhong-Xue Fu
Pages: 1006-1012 Published online on: 15 June 2012
Article
MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1
Yanwei Liu, Wei Yan, Wei Zhang, Lingchao Chen, Gan You, Zhaoshi Bao, Yongzhi Wang, Hongjun Wang, Chunsheng Kang, Tao Jiang
Pages: 1013-1021 Published online on: 05 July 2012
Article
Klotho inhibits the capacity of cell migration and invasion in cervical cancer
Boogi Chang, Jinsun Kim, Dongjun Jeong, Yujun Jeong, Seob Jeon, Sam-Il Jung, Young Yang, Keun Il Kim, Jong-Seok Lim, Changjin Kim, Myeong-Sok Lee
Pages: 1022-1028 Published online on: 14 June 2012
Article
Suppression of growth of A549 lung cancer cells by waltonitone and its mechanisms of action
Yi Zhang, Guo-Bin Zhang, Xiao-Man Xu, Meng Zhang, Dan Qu, Hui-Yan Niu, Xue Bai, Liang Kan, Ping He
Pages: 1029-1035 Published online on: 15 June 2012
Article
Identification of candidate colon cancer biomarkers by applying a random forest approach on microarray data
Zhi Yan, Jiangeng Li, Yimin Xiong, Weitian Xu, Guorong Zheng
Pages: 1036-1042 Published online on: 29 June 2012
Article
Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells
Dong Yeok Shin, Gi-Young Kim, Chan Gil Kim, Wun-Jae Kim, Ho Sung Kang, Yung Hyun Choi
Pages: 1043-1050 Published online on: 12 June 2012
Article
Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma
Angelina Di Carlo
Pages: 1051-1056 Published online on: 14 June 2012
Article
Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect
Sónia Duarte, Agnès Loubat, David Momier, Majlinda Topi, Henrique Faneca, Maria C. Pedroso de Lima, Georges F. Carle, Valérie Pierrefite-Carle
Pages: 1057-1062 Published online on: 06 July 2012
Article
Anti-proliferative and pro-apoptotic effects of 3,3'-diindolylmethane in human cervical cancer cells
Junyong Zhu, Yuan Li, Chao Guan, Zuhua Chen
Pages: 1063-1068 Published online on: 20 June 2012
Article
Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer
Wei-Shone Chen, Chung-Man Leung, Hung-Wei Pan, Ling-Yueh Hu, Sung-Chou Li, Meng-Ru Ho, Kuo-Wang Tsai
Pages: 1069-1076 Published online on: 05 July 2012
Article
Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression
Janine Kah, Andrea Wüstenberg, Amelie Dorothea Keller, Hüseyin Sirma, Roberta Montalbano, Matthias Ocker, Tassilo Volz, Maura Dandri, Gisa Tiegs, Gabriele Sass
Pages: 1077-1083 Published online on: 12 June 2012
Article
IL-5-induced migration via ERK1/2-mediated MMP-9 expression by inducing activation of NF-κB in HT1376 cells
Eo-Jin Lee, Sung-Soo Park, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1084-1090 Published online on: 12 June 2012
Article
Single nucleotide polymorphisms in the regulatory region of gonadotropin-releasing hormone receptor gene and breast cancer susceptibility
Claus Lattrich, Anna-Kristin Müller, Susanne Schüler, Julia Häring, Alexandra Ruoff, Oliver Treeck, Olaf Ortmann
Pages: 1091-1095 Published online on: 12 June 2012
Article
Anti-inflammatory effects of Calophyllum inophyllum L. in RAW264.7 cells
Shih-Chang Tsai, Yu-Hsin Liang, Jo-Hua Chiang, Fon-Chang Liu, Wen-Hsin Lin, Shu-Jen Chang, Wei-Yu Lin, Chieh-Hsi Wu, Jing-Ru Weng
Pages: 1096-1102 Published online on: 19 June 2012
Article
The α-iso-cubebenol compound isolated from Schisandra chinensis induces p53-independent pathway-mediated apoptosis in hepatocellular carcinoma cells
Ji Eun Kim, Sun Guen Kim, Jun Sue Goo, Da Jeong Park, You Jin Lee, In Sik Hwang, Hae Ryeon Lee, Sun Il Choi, Young Ju Lee, Chung Hun Oh, Young Whan Choi, Dae Youn Hwang
Pages: 1103-1109 Published online on: 19 June 2012
Article
Studies on the mechanisms of superagonistic pro-differentiating activities of side-chain modified analogs of vitamin D2
Hanna Baurska, Aleksandra Marchwicka, Anna Kłopot, Andrzej Kutner, Ewa Marcinkowska
Pages: 1110-1116 Published online on: 26 June 2012
Article