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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2013 Volume 30 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Hereditary breast and ovarian cancer susceptibility genes (Review)

Hiroshi Kobayashi, Sumire Ohno, Yoshikazu Sasaki, Miyuki Matsuura
Pages: 1019-1029
Published online on: 19 June 2013

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Article Open Access

Perspective: Opportunities in recalcitrant, rare and neglected tumors

Beverly A. Teicher
Pages: 1030-1034
Published online on: 02 July 2013

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Article Open Access

Induction of apoptosis in MCF-7 cells by the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus Malaysian strain AF2240

Mohamed Ghrici, Mohamed El Zowalaty, Abdul Rahman Omar, Aini Ideris
Pages: 1035-1044
Published online on: 27 June 2013

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Article Open Access

Application of PCR methods to evaluate EGFR, KRAS and BRAF mutations in a small number of tumor cells in cytological material from lung cancer patients

Marzena Anna Lewandowska, Wojciech Jóźwicki, Cezary Jochymski, Janusz Kowalewski
Pages: 1045-1052
Published online on: 01 July 2013

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Article Open Access

Three missense mutations of DNA topoisomerase I in highly camptothecin-resistant colon cancer cell sublines

Yasuhiro Arakawa, Koji Ozaki, Yutaka Okawa, Hisashi Yamada
Pages: 1053-1058
Published online on: 05 July 2013

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Article Open Access

Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrin

Liu-Mei Shou, Qiong-Yan Zhang, Wei Li, Xin Xie, Kai Chen, Lian Lian, Zhen-Yu Li, Fei-Ran Gong, Ke-Sheng Dai, Yi-Xiang Mao, Min Tao
Pages: 1059-1066
Published online on: 08 July 2013

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Article

Advantages of the rapid double-staining method for intraoperative detection of micrometastasis in sentinel lymph nodes

Toshihiko Ojima, Shinichi Kinami, Keishi Nakamura, Katsunobu Oyama, Masashi Inokuchi, Hideto Fujita, Itasu Ninomiya, Sachio Fushida, Takashi Fujimura, Seiko Kitamura, Shinichi Harada, Tetsuo Ohta
Pages: 1067-1072
Published online on: 04 July 2013

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Article

Increased expression of α-actinin-4 is associated with unfavorable pathological features and invasiveness of bladder cancer

Hidehiko Yoshii, Keiichi Ito, Takako Asano, Akio Horiguchi, Masamichi Hayakawa, Tomohiko Asano
Pages: 1073-1080
Published online on: 01 July 2013

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Article

Cetuximab promotes anticancer drug toxicity in rhabdomyosarcomas with EGFR amplification in vitro

Yuki Yamamoto, Kazumasa Fukuda, Yasushi Fuchimoto, Yumi Matsuzaki, Yoshiro Saikawa, Yuko Kitagawa, Yasuhide Morikawa, Tatsuo Kuroda
Pages: 1081-1086
Published online on: 04 July 2013

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Article

Enhanced antitumor activity of trastuzumab emtansine (T-DM1) in combination with pertuzumab in a HER2-positive gastric cancer model

Yoriko Yamashita-Kashima, Sei Shu, Naoki Harada, Kaori Fujimoto-Ouchi
Pages: 1087-1093
Published online on: 19 June 2013

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Article

A phase II study of a personalized peptide vaccination for chemotherapy-resistant advanced pancreatic cancer patients

Shigeru Yutani, Nobukazu Komatsu, Munehiro Yoshitomi, Satoko Matsueda, Koji Yonemoto, Takashi Mine, Masanori Noguchi, Yuki Ishihara, Akira Yamada, Kyogo Itoh, Tetsuro Sasada
Pages: 1094-1100
Published online on: 20 June 2013

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Article

Adenosine potentiates the therapeutic effects of neural stem cells expressing cytosine deaminase against metastatic brain tumors

Wonyoung Kang, Ho Jun Seol, Dong-Ho Seong, Jandi Kim, Yonghyun Kim, Seung U. Kim, Do-Hyun Nam, Kyeung Min Joo
Pages: 1101-1106
Published online on: 03 July 2013

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Article

Berberine induces apoptosis via the mitochondrial pathway in liver cancer cells

Novia K.Y. Yip, W. S. Ho
Pages: 1107-1112
Published online on: 19 June 2013

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Article

Acquisition of paclitaxel resistance via PI3K‑dependent epithelial‑mesenchymal transition in A2780 human ovarian cancer cells

Fangfang Du, Xiaohong Wu, Yanjun Liu, Teng Wang, Xiaowei Qi, Yong Mao, Li Jiang, Yifei Zhu, Yun Chen, Ruiyu  Zhu, Xiaofeng Han, Jian Jin, Xin Ma, Dong Hua
Pages: 1113-1118
Published online on: 26 June 2013

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Article

Glutathione and glutathione peroxidase expression in breast cancer: An immunohistochemical and molecular study

Bruna Victorasso Jardim, Marina Gobbe Moschetta, Camila Leonel, Gabriela Bottaro Gelaleti, Vitor Rafael Regiani, Lívia Carvalho Ferreira, Juliana Ramos Lopes, Debora Ap. Pires de Campos Zuccari
Pages: 1119-1128
Published online on: 13 June 2013

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Article

Pancreatic tumor mass in a xenograft mouse model is decreased by treatment with therapeutic stem cells following introduction of therapeutic genes

Doo-Jin Kim, Bo-Rim Yi, Hye-Rim Lee, Seung U. Kim, Kyung-Chul Choi
Pages: 1129-1136
Published online on: 25 June 2013

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Article

CHD8 is an independent prognostic indicator that regulates Wnt/β-catenin signaling and the cell cycle in gastric cancer

Genta Sawada, Hiroki Ueo, Tae Matsumura, Ryutaro Uchi, Masahisa Ishibashi, Kosuke Mima, Junji Kurashige, Yusuke Takahashi, Sayori Akiyoshi, Tomoya Sudo, Keishi Sugimachi, Yuichiro Doki, Masaki Mori, Koshi Mimori
Pages: 1137-1142
Published online on: 08 July 2013

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Article

Isolation and characterization of biliary epithelial and stromal cells from resected human cholangiocarcinoma: a novel in vitro model to study tumor-stroma interactions

Marco Massani, Tommaso Stecca, Luca Fabris, Ezio Caratozzolo, Cesare Ruffolo, Alberto Furlanetto, Stuart Morton, Massimiliano Cadamuro, Mario Strazzabosco, Nicolò Bassi
Pages: 1143-1148
Published online on: 26 June 2013

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Article

The relevance of EGFR overexpression for the prediction of the malignant transformation of oral leukoplakia

Jutta Ries, Eleftherios Vairaktaris, Abbas Agaimy, Moritz Bechtold, Patricia Gorecki, Friedrich W. Neukam, Emeka Nkenke
Pages: 1149-1156
Published online on: 19 June 2013

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Article

Overexpression of human telomerase reverse transcriptase promotes the motility and invasiveness of HepG2 cells in vitro

Peng-Cheng Chen, Ji-Run Peng, Lei Huang, Wen-Xia Li, Wen-Zhen  Wang, Zhu-Qing-Qing Cui, Hui Han, Lei Gong, Da-Peng Xiang, Shi-Shi  Qiao, Xin Yu, Yu-Hua Wei, Li-Ping Ma, Na Li, Ji-Ye Zhu, Xi-Sheng  Leng
Pages: 1157-1164
Published online on: 25 June 2013

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Article

Enhanced therapeutic efficacy of adenovirus-mediated interleukin-24 gene therapy combined with ionizing radiotherapy for nasopharyngeal carcinoma

Jisheng Liu, Yujuan Zhang, Peng Sun, Yufeng Xie, Jim Xiang, Jicheng Yang
Pages: 1165-1174
Published online on: 19 June 2013

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Article

T-cell apoptosis induced by intratumoral activated hepatic stellate cells is associated with lung metastasis in hepatocellular carcinoma

Yun-Hong Xia, Zhi-Ming Wang, Rong-Xin Chen, Sheng-Long Ye, Rui-Xia Sun, Qiong Xue, Yong Huang
Pages: 1175-1184
Published online on: 27 June 2013

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Article

Identification of molecular candidates and interaction networks via integrative toxicogenomic analysis in a human cell line following low-dose exposure to the carcinogenic metals cadmium and nickel

Jee Young Kwon, Jong-Il Weon, Preeyaporn Koedrith, Kang-Sik Park, Im Soon Kim, Young Rok Seo
Pages: 1185-1194
Published online on: 04 July 2013

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Article

Ammonium chloride enhances cisplatin cytotoxicity through DNA double-strand breaks in human cervical cancer cells

Ye Xu, Ning Wang, Yan Ding, Chunyan Wang, Yang Yu, Shibing Liu, Xiaojun Wang, Zhixin Li
Pages: 1195-1200
Published online on: 20 June 2013

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Article

EtBr-induced selective degradation of mitochondria occurs via autophagy

Yan Luo, Yide Hu, Minghui Zhang, Yu Xiao, Zongchang Song, Yu Xu
Pages: 1201-1208
Published online on: 04 July 2013

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Article

Thymidine kinase/ganciclovir and cytosine deaminase/5-fluorocytosine suicide gene therapy-induced cell apoptosis in breast cancer cells

H. Kong, L. Tao, K. Qi, Y. Wang, Q. Li, J. Du, Z. Huang
Pages: 1209-1214
Published online on: 21 June 2013

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Article

Prevalence of Th17 and Treg cells in gastric cancer patients and its correlation with clinical parameters

Qiaoxia Li, Qingjing Li, Jinxia Chen, Yu Liu, Xuefeng Zhao, Bibo Tan, Jun Ai, Zhiping Zhang, Jingjing Song, Baoen Shan
Pages: 1215-1222
Published online on: 27 June 2013

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Article

Regulation of miR-155 affects pancreatic cancer cell invasiveness and migration by modulating the STAT3 signaling pathway through SOCS1

Chen Huang, Haidong Li, Weidong Wu, Tao Jiang, Zhengjun Qiu
Pages: 1223-1230
Published online on: 28 June 2013

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Article

Induction of human leukemia U937 cell apoptosis by an ethanol extract of Dendropanax morbifera Lev. through the caspase-dependent pathway

Joon Wοο Lee, Cheol Park, Min Hο Han, Su Hyun Hong, Tae Kyung Lee, Shin Hwa Lee, Gi-Young Kim, Yung Hyun Choi
Pages: 1231-1238
Published online on: 19 June 2013

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Article

MicroRNA-128 promotes cell-cell adhesion in U87 glioma cells via regulation of EphB2

Lina Lin, Xulin Chen, Xuelin Peng, Jianwen Zhou, Hsiang-Fu Kung, Marie C. Lin, Songshan Jiang
Pages: 1239-1248
Published online on: 05 July 2013

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Article

Invasion potential of H22 hepatocarcinoma cells is increased by HMGB1-induced tumor NF-κB signaling via initiation of HSP70

Wei Gong, Zhi-Yong Wang, Guo-Xi Chen, Yu-Qiao Liu, Xiao-Yan Gu, Wen-Wei Liu
Pages: 1249-1256
Published online on: 05 July 2013

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Article

Cordycepin increases sensitivity of Hep3B human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by inactivating the JNK signaling pathway

Hye Hyeon Lee, Jin-Woo Jeong, Jun Hyuk Lee, Gi-Young Kim, Jaehun  Cheong, Yong Kee Jeong, Young Hyun Yoo, Yung Hyun Choi
Pages: 1257-1264
Published online on: 04 July 2013

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Article

Profiling of the calcitonin-calcitonin receptor axis in primary prostate cancer: clinical implications and molecular correlates

Arvind Thakkar, Irene V. Bijnsdorp, Albert A. Geldof, Girish V. Shah
Pages: 1265-1274
Published online on: 02 July 2013

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Article

FAM9C plays an anti-apoptotic role through activation of the PI3K/Akt pathway in human hepatocellular carcinoma

Jun-Dong Zhou, Fei Shen, Jian-Song Ji, Kai Zheng, Min Huang, Jin-Chang Wu
Pages: 1275-1284
Published online on: 05 July 2013

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Article

miR-21 and its target gene CCL20 are both highly overexpressed in the microenvironment of colorectal tumors: Significance of their regulation

Benjamin Vicinus, Claudia Rubie, Nathalie Stegmaier, Vilma Oliveira Frick, Kathrin Kölsch, Anne Kauffels, Pirus Ghadjar, Mathias  Wagner, Matthias Glanemann
Pages: 1285-1292
Published online on: 01 July 2013

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Article

Histone deacetylase 4 mediates SMAD family member 4 deacetylation and induces 5-fluorouracil resistance in breast cancer cells

Seong-Lan Yu, Dong Chul Lee, Ji Woong Son, Chang Gyo Park, Hoi Young Lee, Jaeku Kang
Pages: 1293-1300
Published online on: 01 July 2013

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Article

Dual role of TGFBR3 in bladder cancer

Xiao-Long Liu, Kebing Xiao, Boxin Xue, Dongrong Yang, Zhe Lei, Yuxi Shan, Hong-Tao Zhang
Pages: 1301-1308
Published online on: 08 July 2013

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Article

Total alkaloids of Rubus aleaefolius Poir. inhibit the STAT3 signaling pathway leading to suppression of proliferation and cell cycle arrest in a mouse model of hepatocellular carcinoma

Jinyan Zhao, Wei Lin, Zhiyun Cao, Liya Liu, Qunchuan Zhuang, Xiaoyong Zhong, Zhenfeng Hong, Jun Peng
Pages: 1309-1314
Published online on: 03 July 2013

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Article

The overexpression of BAMBI and its involvement in the growth and invasion of human osteosarcoma cells

Lu Zhou, Jin Park, Kyu Yun Jang, Ho Sung Park, Sajeev Wagle, Kyu Hyun Yang, Kwang-Bok Lee, Byung-Hyun Park, Jung Ryul Kim
Pages: 1315-1322
Published online on: 26 June 2013

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Article

Sirt3 is a tumor suppressor in lung adenocarcinoma cells

Kui Xiao, Jiehan Jiang, Wei Wang, Shan Cao, Liming Zhu, Huihui Zeng, Ruoyun Ouyang, Rui Zhou, Ping Chen
Pages: 1323-1328
Published online on: 08 July 2013

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Article

Porphyromonas gingivalis lipopolysaccharide increases lipid accumulation by affecting CD36 and ATP-binding cassette transporter A1 in macrophages

Xiu-Ying Li, Chun Wang, Xue-Rong Xiang, Fang-Chun Chen, Cong-Ming Yang, Jing  Wu
Pages: 1329-1336
Published online on: 08 July 2013

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Article

The insulin-like growth factor-1 and expression of its binding protein‑3 in chronic hepatitis C and hepatocellular carcinoma

Agnieszka Adamek, Aldona Kasprzak, Hanna Mikoś, Wiesława  Przybyszewska, Agnieszka  Seraszek-Jaros, Arkadiusz  Czajka, Karolina  Sterzyńska, Iwona Mozer-Lisewska
Pages: 1337-1345
Published online on: 19 June 2013

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Article

Sterol regulatory element-binding protein 1 is required for ovarian tumor growth

Long-Yun Nie, Qing-Tao Lu, Wei-Hua Li, Ning Yang, Samina Dongol, Xin Zhang, Jie Jiang
Pages: 1346-1354
Published online on: 28 June 2013

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Article

GATA6 predicts prognosis and hepatic metastasis of colorectal cancer

Fei Shen, Jianglin Li, Wensong Cai, Guanghui Zhu, Weili Gu, Lin Jia, Bo Xu
Pages: 1355-1361
Published online on: 19 June 2013

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Article

Ginsenoside Rg3 induces apoptosis in the U87MG human glioblastoma cell line through the MEK signaling pathway and reactive oxygen species

Yoon Ji Choi, Hyun Joo Lee, Dong Wan Kang, In Ho Han, Byung Kwan Choi, Won Ho Cho
Pages: 1362-1370
Published online on: 20 June 2013

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Article

Reduced expression of mutS homolog 2 and mutL homolog 1 affects overall survival in laryngeal squamous cell carcinoma patients: Investigation into a potential cause

Hong-Li Gong, Yong Shi, Yi Shi, Chun-Ping Wu, Peng-Yu Cao, Liang Zhou, Chen Xu
Pages: 1371-1379
Published online on: 20 June 2013

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Article

High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma

Bin Chen, Duo Zhang, Jian Zhou, Qing Li, Lin Zhou, Shi-Min Li, Li Zhu, Kuang-Yen Chou, Liang Zhou, Lei Tao, Li-Ming Lu
Pages: 1380-1390
Published online on: 08 July 2013

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Article

Key genes and pathways in thyroid cancer based on gene set enrichment analysis

Wenwu He, Bin Qi, Qiuxi Zhou, Chuansen Lu, Qi Huang, Lei Xian, Mingwu Chen
Pages: 1391-1397
Published online on: 20 June 2013

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Article

miR‑133a suppresses cell proliferation, migration and invasion in human lung cancer by targeting MMP‑14

Meng Xu, Yu‑Zhou Wang
Pages: 1398-1404
Published online on: 19 June 2013

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Article

Antitumour effects of Yangzheng Xiaoji in human osteosarcoma: The pivotal role of focal adhesion kinase signalling

Wen G. Jiang, Lin Ye, Ke Ji, Fiona Ruge, Yiling Wu, Yong Gao, Jiafu Ji, Malcolm D. Mason
Pages: 1405-1413
Published online on: 03 July 2013

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Article

Overexpression of astrocyte-elevated gene-1 is associated with cervical carcinoma progression and angiogenesis

Min Long, Ke Dong, Ping Gao, Xi Wang, Li Liu, Shuhui Yang, Fang Lin, Junxia Wei, Huizhong Zhang
Pages: 1414-1422
Published online on: 08 July 2013

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Article

Notch1 destabilizes the adherens junction complex through upregulation of the Snail family of E-cadherin repressors in non-small cell lung cancer

Arum Kim, Eun Young Kim, Eun Na Cho, Hyung Jung Kim, Se Kyu Kim, Joon Chang, Chul Min Ahn, Yoon Soo Chang
Pages: 1423-1429
Published online on: 26 June 2013

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Article

Inhibition of Wnt signaling induces cell apoptosis and suppresses cell proliferation in cholangiocarcinoma cells

Kun-Song Zhang, Qi Zhou, Ya-Feng Wang, Li-Jian Liang
Pages: 1430-1438
Published online on: 21 June 2013

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Article

Patrinia scabiosaefolia inhibits colorectal cancer growth through suppression of tumor angiogenesis

Liwu Chen, Liya Liu, Ling Ye, Aling Shen, Youqin Chen, Thomas J. Sferra, Jun  Peng
Pages: 1439-1443
Published online on: 02 July 2013

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Article

Molecular basis for the regulation of hypoxia-inducible factor-1α levels by 2-deoxy-D-ribose

Ryuji Ikeda, Sho Tabata, Yusuke Tajitsu, Yukihiko Nishizawa, Kentaro Minami, Tatsuhiko Furukawa, Masatatsu Yamamoto, Yoshinari Shinsato, Shin-Ichi Akiyama, Katsushi Yamada, Yasuo Takeda
Pages: 1444-1448
Published online on: 27 June 2013

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Article

Loss of the metastasis suppressor gene KiSS1 is associated with lymph node metastasis and poor prognosis in human colorectal cancer

Yoshinaga Okugawa, Yasuhiro Inoue, Koji Tanaka, Yuji Toiyama, Tadanobu Shimura, Masato Okigami, Aya Kawamoto, Junichiro Hiro, Susumu Saigusa, Yasuhiko Mohri, Keiichi Uchida, Masato Kusunoki
Pages: 1449-1454
Published online on: 20 June 2013

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Article

Human erythropoietin increases the pro-angiogenic potential of A2780 ovarian adenocarcinoma cells under hypoxic conditions

Ján Kriška, Peter Solár, Lenka Varinská, Zuzana Solárová, Patrícia Kimáková, Ján Mojžiš, Peter Fedoročko, Arthur J. Sytkowski
Pages: 1455-1462
Published online on: 26 June 2013

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Predictive and prognostic factors in second- and third-line erlotinib treatment in NSCLC patients with known status of the EGFR gene

Paweł Krawczyk, Dariusz M. Kowalski, Kamila Wojas Krawczyk, Michał  Szczyrek, Radosław Mlak, Andrzej Rolski, Aneta Szudy, Robert  Kieszko, Kinga  Winiarczyk, Janusz Milanowski, Maciej Krzakowski
Pages: 1463-1472
Published online on: 19 June 2013

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Artesunate exerts specific cytotoxicity in retinoblastoma cells via CD71

Fei Zhao, Han Wang, Patricilia Kunda, Xuemei Chen, Qiu-Ling Liu, Tao Liu
Pages: 1473-1482
Published online on: 28 June 2013

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Lentivirus-delivered short hairpin RNA targeting SNAIL inhibits HepG2 cell growth

Jing Liu, Gang Jiang, Shihai Liu, Zimin Liu, Huazheng Pan, Ruyong Yao, Jun Liang
Pages: 1483-1487
Published online on: 19 June 2013

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Article

Microarray analysis reveals that high mobility group A1 is involved in colorectal cancer metastasis

Yusuke Takahashi, Genta Sawada, Tetsuya Sato, Junji Kurashige, Kosuke Mima, Tae Matsumura, Ryutaro Uchi, Hiroki Ueo, Masahisa Ishibashi, Yuki Takano, Sayuri Akiyoshi, Hidetoshi Eguchi, Tomoya Sudo, Keishi Sugimachi, Jun‑Ichi Tanaka, Shin-Ei Kudo, Yuichiro Doki, Masaki Mori, Koshi Mimori
Pages: 1488-1496
Published online on: 08 July 2013

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Article

Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells

Kun-Huang Yan, Liang-Ming Lee, Mao-Chih Hsieh, Ming-De Yan, Chih-Jung Yao, Pey-Yi Chang, Tsung-Li Chen, Hwan-You Chang, Ann-Lii Cheng, Gi-Ming Lai, Shuang-En Chuang
Pages: 1497-1505
Published online on: 21 June 2013

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Article

Cyclooxygenase-2 utilizes Jun N-terminal kinases to induce invasion, but not tamoxifen resistance, in MCF-7 breast cancer cells

Vianey Gonzalez-Villasana, Yolanda Gutiérrez-Puente, Ana M. Tari
Pages: 1506-1510
Published online on: 19 June 2013

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Article

Promoter methylation of the DLC‑1 gene and its inhibitory effect on human colon cancer

Zhensheng Dai, Yueling Jin
Pages: 1511-1517
Published online on: 19 June 2013

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Article

The trefoil factor 1 (TFF1) protein involved in doxorubicin‑induced apoptosis resistance is upregulated by estrogen in breast cancer cells

Sonam Pelden, Tonkla Insawang, Chanitra Thuwajit, Peti Thuwajit
Pages: 1518-1526
Published online on: 05 July 2013

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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