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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2014 Volume 32 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Targeting forkhead box transcription factors FOXM1 and FOXO in leukemia (Review)

Hong Zhu
Pages: 1327-1334
Published online on: 23 July 2014

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Article Open Access

Role of Lifeguard β-isoform in the development of breast cancer

Nadjib Dastagir, Andrea Lazaridis, Khaled Dastagir, Kerstin Reimers, Peter M. Vogt, Vesna Bucan
Pages: 1335-1340
Published online on: 25 July 2014

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Article Open Access

Phloroglucinol induces apoptosis via apoptotic signaling pathways in HT-29 colon cancer cells

Mi-Hye Kang, In-Hye Kim, Taek-Jeong Nam
Pages: 1341-1346
Published online on: 23 July 2014

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Article Open Access

TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions

Gun-Hoo Park, Su-Jin Lee, Hyunee Yim, Jae-Ho Han, Hyon J. Kim, Young-Bae  Sohn, Jung Min Ko, Seon-Yong Jeong
Pages: 1347-1354
Published online on: 04 August 2014

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Article Open Access

Invasive micropapillary carcinoma of the extrahepatic bile duct and its malignant potential

Tadashi Yoshizawa, Yoshikazu Toyoki, Hideaki Hirai, Toshihiro  Haga, Takahito Toba, Shingo Sakuraba, Kensuke Okano, Yunyan Wu, Hiroko  Seino, Satoko Morohashi, Kenichi Hakamada, Hiroshi Kijima
Pages: 1355-1361
Published online on: 07 August 2014

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Article Open Access

WWOX modulates the gene expression profile in the T98G glioblastoma cell line rendering its phenotype less malignant

Katarzyna Kośla, Magdalena Nowakowska, Karolina Pospiech, Andrzej K. Bednarek
Pages: 1362-1368
Published online on: 17 July 2014

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Article Open Access

SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling

Huaping Xiong, Jicheng Wang, Hongyu Guan, Jueheng Wu, Ru Xu, Min Wang, Xia Rong, Ke Huang, Jieting Huang, Qiao Liao, Yongshui Fu, Jie Yuan
Pages: 1369-1373
Published online on: 07 August 2014

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Article

A comprehensive search for microRNAs with expression profiles modulated by oncogenic KRAS: Potential involvement of miR-31 in lung carcinogenesis

Koji Okudela, Takeshisa Suzuki, Shigeaki  Umeda, Yoko  Tateishi, Hideaki  Mitsui, Yohei  Miyagi, Kenichi  Ohashi
Pages: 1374-1384
Published online on: 18 July 2014

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Article

Mead acid inhibits the growth of KPL-1 human breast cancer cells in vitro and in vivo

Yuichi Kinoshita, Katsuhiko Yoshizawa, Kei Hamazaki, Yuko Emoto, Takashi Yuri, Michiko Yuki, Nobuaki Shikata, Hiroshi Kawashima, Airo Tsubura
Pages: 1385-1394
Published online on: 07 August 2014

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Article

Inhibition of Rac1 activity induces G1/S phase arrest through the GSK3/cyclin D1 pathway in human cancer cells

Linna Liu, Hongmei Zhang, Lei Shi, Wenjuan Zhang, Juanli Yuan, Xiang Chen, Juanjuan Liu, Yan Zhang, Zhipeng Wang
Pages: 1395-1400
Published online on: 07 August 2014

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Article

Induced IGF-1R activation contributes to gefitinib resistance following combined treatment with paclitaxel, cisplatin and gefitinib in A549 lung cancer cells

Xiaojun Ge, Qingjuan Chen, Yang Ping Wu, Yuchen  Zhang, Hongwei Xia, Dandan  Yuan, Qi  Chen, Weibing  Leng, Liang  Chen, Qiulin  Tang, Xiaohui  Pang, Feng Bi
Pages: 1401-1408
Published online on: 15 July 2014

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Article

MicroRNA-100 promotes migration and invasion through mammalian target of rapamycin in esophageal squamous cell carcinoma

Naijian Zhang, Hailong Fu, Leilei Song, Youhong Ding, Xiufang Wang, Chao Zhao, Yiqi Zhao, Feng Jiao, Yaping Zhao
Pages: 1409-1418
Published online on: 07 August 2014

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Article

KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy

L. S. Yamane, C. Scapulatempo-Neto, L. Alvarenga, C. Z. Oliveira, G. N. Berardinelli, E. Almodova, T. R. Cunha, G. Fava, W. Colaiacovo, A. Melani, J. H. Fregnani, R. M. Reis, D. P. Guimarães
Pages: 1419-1426
Published online on: 18 July 2014

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Article

Differential protein expression and novel biomarkers related to 5-FU resistance in a 3D colorectal adenocarcinoma model

Sang-Hak Lee, Jae Kook Nam, Jong-Kook Park, Joo-Ho Lee, Do Sik Min, Hyo-Jeong Kuh
Pages: 1427-1434
Published online on: 18 July 2014

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Article

Variability in the measurement of the methylation status of lung cancer-related genes in bronchial secretions

Laura Millares, Antoni Rosell, Laia Setó, José Sanz, Felipe Andreo, Eduard Monsó
Pages: 1435-1440
Published online on: 28 July 2014

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Article

Expression of BAG-1 is closely related to cell differentiation and TNM stage in esophageal cancer and its downregulation inhibits the proliferation and invasion of human esophageal carcinoma cells

Bo Huang, Hongli Zhou, Xianping Lang, Zhiliang Liu, Fei Xiong, Siwang Wang
Pages: 1441-1446
Published online on: 23 July 2014

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Article

Genetic analysis of an orbital metastasis from a primary hepatic neuroendocrine carcinoma

Jacob Ø. Rasmussen, Sarah L. von Holstein, Jan U. Prause, Ben Vainer, Alastair B. Hansen, André Fehr, Göran Stenman, Steffen Heegaard
Pages: 1447-1450
Published online on: 21 July 2014

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Article

USP22 promotes epithelial-mesenchymal transition via the FAK pathway in pancreatic cancer cells

Zhen Ning, Aman Wang, Jinxiao Liang, Yunpeng  Xie, Jiwei Liu, Qiu Yan, Zhongyu Wang
Pages: 1451-1458
Published online on: 23 July 2014

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Article

Notch-1 regulates proliferation and differentiation of human bladder cancer cell lines by inhibiting expression of Krüppel-like factor 4

Xing Ai, Zhuomin Jia, Shuanglin Liu, Jiajun Wang, Xu Zhang
Pages: 1459-1464
Published online on: 23 July 2014

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Article

Activation of phosphatidylinositol 3-kinase/Akt signaling mediates sorafenib-induced invasion and metastasis in hepatocellular carcinoma

Haiyong Wang, Litao Xu, Xiaoyan Zhu, Peng Wang, Huiying Chi, Zhiqiang Meng
Pages: 1465-1472
Published online on: 23 July 2014

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Article

4-Amino-2-trifluoromethyl-phenyl retinate inhibits the migration of BGC-823 human gastric cancer cells by downregulating the phosphorylation level of MLC II

Anla Hu, Yanyan Yang, Sumei Zhang, Qing Zhou, Wei Wei, Yuan Wang
Pages: 1473-1480
Published online on: 18 July 2014

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Article

Paclitaxel-loaded trimethyl chitosan-based polymeric nanoparticle for the effective treatment of gastroenteric tumors

Rong-Feng Song, Xiao-Jun Li, Xiao-Liang Cheng, Ai-Rong  Fu, Yan-Hua Wang, Yan-Jun Feng, Yan Xiong
Pages: 1481-1488
Published online on: 21 July 2014

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Article

Far from resolved: Stromal cell-based iTRAQ research of muscle-invasive bladder cancer regarding heterogeneity

Peng-Fei Liu, Yong-Hua Wang, Yan-Wei Cao, Hai-Ping Jiang, Xue-Cheng Yang, Xin-Sheng Wang, Hai-Tao Niu
Pages: 1489-1496
Published online on: 18 July 2014

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Article

Knockdown of galectin-1 suppresses the growth and invasion of osteosarcoma cells through inhibition of the MAPK/ERK pathway

Jin-Hao Miao, Shu-Qiang Wang, Ming-Hui  Zhang, Feng‑Bin  Yu, Lei  Zhang, Zhong-Xiang Yu, Yong Kuang
Pages: 1497-1504
Published online on: 24 July 2014

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Article

RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cells through activation of MST1/LATS1 signaling

Xu-Hui Zhou, Chao-Qun Yang, Cheng-Lin  Zhang, Yang Gao, Hong-Bin  Yuan, Ce Wang
Pages: 1505-1512
Published online on: 07 August 2014

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Article

Downregulation of phosphoglycerate kinase 1 by shRNA sensitizes U251 xenografts to radiotherapy

Yi-Jun Cheng, Hao Ding, Hua-Qing Du, Hua  Yan, Jin-Bing Zhao, Wen-Bin Zhang, Yuan-Jie Zou, Hong-Yi  Liu, Hong Xiao
Pages: 1513-1520
Published online on: 23 July 2014

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Article

Prostaglandin E2 promotes the cell growth and invasive ability of hepatocellular carcinoma cells by upregulating c-Myc expression via EP4 receptor and the PKA signaling pathway

Shukai Xia, Juan Ma, Xiaoming Bai, Hai Zhang, Shanyu  Cheng, Min Zhang, Li Zhang, Mingzhan Du, Yipin  Wang, Hai Li, Rong Rong, Feng Shi, Qinyi Yang, Jing Leng
Pages: 1521-1530
Published online on: 07 August 2014

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Article

Broussonetia kazinoki modulates the expression of VEGFR-2 and MMP-2 through the inhibition of ERK, Akt and p70S6K‑dependent signaling pathways: Its implication in endothelial cell proliferation, migration and tubular formation

Young-Rak Cho, Jae Hyeon Kim, Jin-Kyu Kim, Eun-Kyung Ahn, Hye-Jin Ko, Jae Kyung In, Sang-Jin Lee, Gyu-Un Bae, Yong Kee Kim, Joa Sub Oh, Dong-Wan Seo
Pages: 1531-1536
Published online on: 04 August 2014

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Article

NRP-1 expression is strongly associated with the progression of pituitary adenomas

Sang Won Lee, Jung Eun Lee, Chang Young Yoo, Myoung Seok Ko, Chan Soon Park, Seung-Ho Yang
Pages: 1537-1542
Published online on: 07 August 2014

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Article

Effects of lentivirus-mediated RNAi knockdown of NEDD9 on human lung adenocarcinoma cells in vitro and in vivo

Jing-Xia Chang, Feng Gao, Guo-Qiang Zhao, Guo-Jun Zhang
Pages: 1543-1549
Published online on: 22 July 2014

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Article

Serum anti-osteopontin autoantibody as a novel diagnostic and prognostic biomarker in patients with hepatocellular carcinoma

Xia Ying, Yue Zhao, Jun-Lan Wang, Xia Zhou, Jing Zhao, Chen-Chen He, Xi-Jing Guo, Gui-Hua Jin, Li-Juan Wang, Qing Zhu, Su-Xia Han
Pages: 1550-1556
Published online on: 30 July 2014

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Article

Arsenic trioxide induces autophagy and antitumor effects in Burkitt's lymphoma Raji cells

Cai-Li Li, Hu-Lai Wei, Jing Chen, Bei Wang, Bei Xie, Lin-Lan Fan, Lin-Jing Li
Pages: 1557-1563
Published online on: 30 July 2014

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Article

AQP5: A novel biomarker that predicts poor clinical outcome in colorectal cancer

Tao Shan, Xijuan Cui, Wei Li, Wanrun Lin, Yiming Li
Pages: 1564-1570
Published online on: 04 August 2014

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Article

Prognostic significance of miR-218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Pages: 1571-1577
Published online on: 07 August 2014

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Article

Knockdown of ubiquitin associated protein 2-like inhibits the growth and migration of prostate cancer cells

Dong Li, Yiran Huang
Pages: 1578-1584
Published online on: 25 July 2014

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Article

Isoalantolactone inhibits constitutive NF-κB activation and induces reactive oxygen species-mediated apoptosis in osteosarcoma U2OS cells through mitochondrial dysfunction

Weihua Di, Muhammad Khan, Azhar Rasul, Meiyan Sun, Yujie Sui, Lili  Zhong, Longfei Yang, Qi Zhu, Liangtao Feng, Tonghui Ma
Pages: 1585-1593
Published online on: 30 July 2014

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Article

YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis

Jian-Jia Cao, Xiu-Min Zhao, De-Lin  Wang, Ke-Hong  Chen, Xia  Sheng, Wen-Bin  Li, Mei-Cai  Li, Wu-Jiang  Liu, Jiang He
Pages: 1594-1600
Published online on: 22 July 2014

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Article

Assessment of insulin-like growth factor 1 receptor as an oncogene in esophageal squamous cell carcinoma and its potential implication in chemotherapy

Wang Ma, Tengfei Zhang, Jian Pan, Ni Shi, Qingxia Fan, Liuxing Wang, Shih Hsin Lu
Pages: 1601-1609
Published online on: 22 July 2014

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Article

Curcumin sensitizes glioblastoma to temozolomide by simultaneously generating ROS and disrupting AKT/mTOR signaling

Haitao Yin, Yun Zhou, Cuixia Wen, Chong Zhou, Wei Zhang, Xiang Hu, Lifeng Wang, Chuanwen You, Junfei Shao
Pages: 1610-1616
Published online on: 18 July 2014

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Article

PEG-liposomal oxaliplatin combined with nuclear factor-κB inhibitor (PDTC) induces apoptosis in human colorectal cancer cells

Chuang Yang, Zhong-Xue Fu
Pages: 1617-1621
Published online on: 17 July 2014

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Article

Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis

Wei Xiang, Ting Jiang, Fengjing Guo, Chen Gong, Kaixiang Yang, Yingxing Wu, Xin Huang, Weiting Cheng, Kai Xu
Pages: 1622-1630
Published online on: 31 July 2014

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Article

KPNA2 is a promising biomarker candidate for esophageal squamous cell carcinoma and correlates with cell proliferation

Shouzhi Ma, Xiaohang Zhao
Pages: 1631-1637
Published online on: 04 August 2014

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Article

High ALDHdim-expressing CD34+CD38- cells in leukapheresed peripheral blood is a reliable guide for a successful leukemic xenograft model of acute myeloid leukemia

Ji Yoon Lee, Sohye Park, A-Reum Han, Jihyang Lim, Woo-Sung Min, Hee-Je Kim
Pages: 1638-1646
Published online on: 24 July 2014

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Article

Synergistic cytotoxic effect of genistein and doxorubicin on drug-resistant human breast cancer MCF-7/Adr cells

Jia-Peng Xue, Geng Wang, Zong-Bin Zhao, Qun Wang, Yun Shi
Pages: 1647-1653
Published online on: 29 July 2014

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Article

Contrast-enhanced color Doppler ultrasonography increases diagnostic accuracy for soft tissue tumors

Naoto Oebisu, Manabu Hoshi, Makoto Ieguchi, Jun  Takada, Tadashi Iwai, Masahiko Ohsawa, Hiroaki Nakamura
Pages: 1654-1660
Published online on: 04 August 2014

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Article

Hotspot mutations in common oncogenes are infrequent in nasopharyngeal carcinoma

Ning Jiang, Na Liu, Fan Yang, Qiming Zhou, Ruixue Cui, Wei Jiang, Qingmei  He, Wenfei Li, Ying Guo, Jing Zeng, Jingping Yun, Xinchun Chen, Boping Zhou, Ying Sun, Huiyun Wang, Zhuo G. Chen, Jun Ma
Pages: 1661-1669
Published online on: 01 August 2014

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Article

Identification of aspirin analogues that repress NF-κB signalling and demonstrate anti-proliferative activity towards colorectal cancer in vitro and in vivo

Ann-Katrin Claudius, Chandra S. Kankipati, Rajagopal S. Kilari, Sadiya Hassan, Kerry Guest, Steven T. Russell, Chris J. Perry, Lesley A. Stark, Iain D. Nicholl
Pages: 1670-1680
Published online on: 31 July 2014

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Article

Combined cetuximab and celecoxib treatment exhibits a synergistic anticancer effect on human oral squamous cell carcinoma in vitro and in vivo

Ming Qian, Donghua Qian, Hongyu Jing, Yang Li, Chengyuan Ma, Yanmin Zhou
Pages: 1681-1688
Published online on: 16 July 2014

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Article

CIP2A regulates cell proliferation via the AKT signaling pathway in human lung cancer

Ningjing Lei, Bo Peng, Jian-Ying Zhang
Pages: 1689-1694
Published online on: 01 August 2014

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Article

Influence of mutation type on prognostic and predictive values of TP53 status in primary breast cancer patients

Petr Dobes, Jan Podhorec, Oldrich  Coufal, Andrea  Jureckova, Katarina  Petrakova, Borivoj  Vojtesek, Roman Hrstka
Pages: 1695-1702
Published online on: 21 July 2014

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Article

Effect of nitric oxide synthase on multiple drug resistance is related to Wnt signaling in non-small cell lung cancer

Yang Li, Chengyuan Ma, Xu Shi, Zhongmei Wen, Dan Li, Munan Sun, Hui Ding
Pages: 1703-1708
Published online on: 23 July 2014

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Article

Bradykinin stimulates IL-6 production and cell invasion in colorectal cancer cells

Guojun Wang, Yanwei Ye, Xiefu Zhang, Junmin Song
Pages: 1709-1714
Published online on: 30 July 2014

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Article

Cancer cells release anaphylatoxin C5a from C5 by serine protease to enhance invasiveness

Hidetoshi Nitta, Yoji  Murakami, Yoshihiro  Wada, Masatoshi  Eto, Hideo  Baba, Takahisa  Imamura
Pages: 1715-1719
Published online on: 18 July 2014

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Article

MicroRNA-145 is a potential prognostic factor of scirrhous type gastric cancer

Yutaka Naito, Kyohei Yasuno, Hiroko Tagawa, Naoya  Sakamoto, Naohide  Oue, Masakazu  Yashiro, Kazuhiro  Sentani, Keisuke  Goto, Shunsuke  Shinmei, Htoo  Zarni Oo, Kazuyoshi Yanagihara, Kosei Hirakawa, Wataru Yasui
Pages: 1720-1726
Published online on: 16 July 2014

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Article

Cholesterol synthesis inhibitor RO 48-8071 suppresses transcriptional activity of human estrogen and androgen receptor

Benford Mafuvadze, Yayun Liang, Salman M. Hyder
Pages: 1727-1733
Published online on: 15 July 2014

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Article

MicroRNA-183 is involved in cell proliferation, survival and poor prognosis in pancreatic ductal adenocarcinoma by regulating Bmi-1

Liang Zhou, Wei-Guo Zhang, De-Sheng  Wang, Kai‑Shan  Tao, Wen-Jie Song, Ke-Feng  Dou
Pages: 1734-1740
Published online on: 01 August 2014

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Article

Effect of the PTEN gene on adhesion, invasion and metastasis of osteosarcoma cells

Yong Hu, Shenglin Xu, Wensen Jin, Qiyi Yi, Wei  Wei
Pages: 1741-1747
Published online on: 25 July 2014

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Article

Diallyl disulfide induces G2/M arrest and promotes apoptosis through the p53/p21 and MEK-ERK pathways in human esophageal squamous cell carcinoma

Xiaoran Yin, Rong Zhang, Cheng Feng, Jun Zhang, Dong Liu, Kun Xu, Xijing Wang, Shuqun Zhang, Zongfang Li, Xinlian Liu, Hongbing Ma
Pages: 1748-1756
Published online on: 25 July 2014

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January-2026 Volume 55 Issue 1

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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