Journal Articles
Review
Role of microRNAs in progenitor cell commitment and osteogenic differentiation in health and disease (Review)
Maria Teresa Valenti, Luca Dalle Carbonare, Monica Mottes
Pages: 2441-2449 Published online on: 01 February 2018
Article
Sphingosine kinase inhibitors: A patent review
Mengda Cao, Chunmei Ji, Yanjun Zhou, Wen Huang, Weiwei Ni, Xunliang Tong, Ji-Fu Wei
Pages: 2450-2460 Published online on: 20 February 2018
Article
Hypoxia induces pulmonary arterial fibroblast proliferation, migration, differentiation and vascular remodeling via the PI3K/Akt/p70S6K signaling pathway
Xiaoyu Chai, Dan Sun, Qian Han, Liang Yi, Yanping Wu, Xinmin Liu
Pages: 2461-2472 Published online on: 06 February 2018
Article
Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells
Daguang Wang, Yabin Sun, Wei Li, Fei Ye, Yang Zhang, Yuchen Guo, David Y. Zhang, Jian Suo
Pages: 2473-2484 Published online on: 06 February 2018
Article
Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS
Kang Li, Yan Li, Jie Mi, Lu Mao, Xiuguo Han, Jie Zhao
Pages: 2485-2492 Published online on: 06 February 2018
Article
Stage‑dependent changes of β2‑adrenergic receptor signaling in right ventricular remodeling in monocrotaline‑induced pulmonary arterial hypertension
Fengjiao Sun, Zhiqiang Lu, Yidan Zhang, Shihan Geng, Mengxi Xu, Liman Xu, Yingying Huang, Pengwei Zhuang, Yanjun Zhang
Pages: 2493-2504 Published online on: 01 February 2018
Article
Seawater inhalation induces acute lung injury via ROS generation and the endoplasmic reticulum stress pathway
Peng‑Cheng Li, Bo‑Rong Wang, Cong‑Cong Li, Xi Lu, Wei‑Sheng Qian, Yu‑Juan Li, Fa‑Guang Jin, De‑Guang Mu
Pages: 2505-2516 Published online on: 12 February 2018
Article
Mangiferin inhibits apoptosis and oxidative stress via BMP2/Smad-1 signaling in dexamethasone-induced MC3T3-E1 cells
Ling-Zhi Ding, Xiao Teng, Zhao-Bo Zhang, Chang-Jun Zheng, Shi-Hong Chen
Pages: 2517-2526 Published online on: 20 February 2018
Article
Tracking of transplanted human umbilical cord-derived mesenchymal stem cells labeled with fluorescent probe in a mouse model of acute lung injury
Genglong Liu, Haijin Lv, Yuling An, Xuxia Wei, Xiaomeng Yi, Huimin Yi
Pages: 2527-2534 Published online on: 13 February 2018
Article
AMP-activated protein kinase stimulates osteoblast differentiation and mineralization through autophagy induction
Yi Li, Jiajia Su, Wenchao Sun, Lin Cai, Zhouming Deng
Pages: 2535-2544 Published online on: 16 February 2018
Article
Human umbilical cord mesenchymal stem cells inhibit proliferation of hepatic stellate cells in vitro
Li-Ting Zhang, Xue-Bin Peng, Xue-Qin Fang, Jun-Feng Li, Hong Chen, Xiao-Rong Mao
Pages: 2545-2552 Published online on: 16 February 2018
Article
Transplantation of allogenic nucleus pulposus cells attenuates intervertebral disc degeneration by inhibiting apoptosis and increasing migration
Weiheng Wang, Guoying Deng, Yuanyuan Qiu, Xiaodong Huang, Yanhai Xi, Jiangming Yu, Xiangqun Yang, Xiaojian Ye
Pages: 2553-2564 Published online on: 02 February 2018
Article
Necrostatin-1 protects C2C12 myotubes from CoCl2-induced hypoxia
Rui Chen, Jiehua Xu, Yanling She, Ting Jiang, Shanyao Zhou, Huacai Shi, Cheng Li
Pages: 2565-2572 Published online on: 06 February 2018
Article
Inhibition of cell migration by focal adhesion kinase: Time-dependent difference in integrin-induced signaling between endothelial and hepatoblastoma cells
Hongchi Yu, Min Gao, Yunlong Ma, Lijuan Wang, Yang Shen, Xiaoheng Liu
Pages: 2573-2588 Published online on: 23 February 2018
Article
Novel iridium (III)‑derived organometallic compound for the inhibition of human platelet activation Corrigendum in /10.3892/ijmm.2019.4177
Kou‑Gi Shyu, Marappan Velusamy, Chih‑Wei Hsia, Chih‑Hao Yang, Chih‑Hsuan Hsia, Duen‑Suey Chou, Thanasekaran Jayakumar, Joen‑Rong Sheu, Jiun‑Yi Li
Pages: 2589-2600 Published online on: 07 February 2018
Article
LicA induces autophagy through ULK1/Atg13 and ROS pathway in human hepatocellular carcinoma cells
Qiang Niu, Wei Zhao, Jin Wang, Chunming Li, Tao Yan, Wei Lv, Guojing Wang, Weihong Duan, Tao Zhang, Kunnan Wang, Dinghua Zhou
Pages: 2601-2608 Published online on: 16 February 2018
Article
Decreased hyperpolarization-activated cyclic nucleotide-gated channels are involved in bladder dysfunction associated with spinal cord injury
Qian Liu, Chao Wu, Shengquan Huang, Qingjian Wu, Tao Zhou, Xiaobing Liu, Xin Liu, Xiaoyan Hu, Longkun Li
Pages: 2609-2618 Published online on: 13 February 2018
Article
DFMG attenuates the activation of macrophages induced by co‑culture with LPC‑injured HUVE‑12 cells via the TLR4/MyD88/NF‑κB signaling pathway
Li Cong, Shuting Yang, Yong Zhang, Jianguo Cao, Xiaohua Fu
Pages: 2619-2628 Published online on: 23 February 2018
Article
Early intervention with mesenchymal stem cells prevents nephropathy in diabetic rats by ameliorating the inflammatory microenvironment
Yuanmin Li, Jingping Liu, Guangneng Liao, Jie Zhang, Younan Chen, Lan Li, Li Li, Fang Liu, Bo Chen, Gang Guo, Chengshi Wang, Lichuan Yang, Jingqiu Cheng, Yangrong Lu
Pages: 2629-2639 Published online on: 16 February 2018
Article
The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion
Binyu Luo, Kang Chen, Qi Feng, Weidong Xiao, Dan Ma, Hua Yang, Chaojun Zhang
Pages: 2640-2650 Published online on: 09 February 2018
Article
Methylation-induced downregulation and tumor-suppressive role of microRNA-98 in glioma through targeting Sal-like protein 4 Retraction in /10.3892/ijmm.2021.4962
Zhiwei Xia, Dongxu Qiu, Jun Deng, Xiao Jiao, Ronghe Yang, Zhongyi Sun, Xin Wan, Jing Li
Pages: 2651-2659 Published online on: 06 February 2018
Article
BCL6B suppresses proliferation and migration of colorectal carcinoma cells through inhibition of the PI3K/AKT signaling pathway
Yue Gu, Aifang Li, Hui Sun, Xueru Li, He Zha, Jiali Zhao, Jiaqing Xie, Zongyue Zeng, Lan Zhou
Pages: 2660-2668 Published online on: 01 February 2018
Article
Protective effect of adenovirus-mediated erythropoietin expression on the spiral ganglion neurons in the rat inner ear
Cheng Zhong, Zhendong Jiang, Qiang Guo, Xueyuan Zhang
Pages: 2669-2677 Published online on: 05 February 2018
Article
Iron limitation promotes the atrophy of skeletal myocytes, whereas iron supplementation prevents this process in the hypoxic conditions
Kamil Kobak, Monika Kasztura, Magdalena Dziegala, Jacek Bania, Violetta Kapuśniak, Waldemar Banasiak, Piotr Ponikowski, Ewa A. Jankowska
Pages: 2678-2686 Published online on: 12 February 2018
Article
Microenvironment‑driven resistance to B‑Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts
Ondřej Kodet, Barbora Dvořánková, Běla Bendlová, Vlasta Sýkorová, Ivana Krajsová, Jiří Štork, Jan Kučera, Pavol Szabo, Hynek Strnad, Michal Kolář, Čestmír Vlček, Karel Smetana, Lukáš Lacina
Pages: 2687-2703 Published online on: 01 February 2018
Article
Long noncoding RNA ENSRNOG00000037522 is involved in the podocyte epithelial‑mesenchymal transition in diabetic rats
Li Ling, Zhen Tan, Changning Zhang, Shuyan Gui, Yuanyuan Hu, Libo Chen
Pages: 2704-2714 Published online on: 05 February 2018
Article
Cognitive improvement following ischemia/reperfusion injury induced by voluntary running‑wheel exercise is associated with LncMALAT1‑mediated apoptosis inhibition
Jin‑Lin Shang, Qing Cheng, Sheng‑Jie Duan, Lu Li, Li‑Ya Jia
Pages: 2715-2723 Published online on: 12 February 2018
Article
Identification of novel hyper- or hypomethylated CpG sites and genes associated with atherosclerotic plaque using an epigenome-wide association study
Yoshiji Yamada, Hideki Horibe, Mitsutoshi Oguri, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Motoji Sawabe
Pages: 2724-2732 Published online on: 02 February 2018
Article
microRNA expression profiles of scar and normal tissue from patients with posterior urethral stricture caused by pelvic fracture urethral distraction defects
Kaile Zhang, Jun Chen, Dongliang Zhang, Lin Wang, Weixin Zhao, David Yun-Te Lin, Rong Chen, Hong Xie, Xiaoyong Hu, Xiaolan Fang, Qiang Fu
Pages: 2733-2743 Published online on: 12 February 2018
Article
Structural characterization, immune regulation and antioxidant activity of a new heteropolysaccharide from Cantharellus cibarius Fr.
Daqun Zhao, Xiang Ding, Yiling Hou, Wanru Hou, Lu Liu, Ting Xu, Danni Yang
Pages: 2744-2754 Published online on: 01 February 2018
Article
LMO3 promotes gastric cancer cell invasion and proliferation through Akt-mTOR and Akt-GSK3β signaling
Yan-Song Qiu, Ning-Ning Jiang, Yan Zhou, Kuai-Yun Yu, Hong-Yan Gong, Guang-Jun Liao
Pages: 2755-2763 Published online on: 08 February 2018
Article
Experimental study on the neurotoxic effect of β-amyloid on the cytoskeleton of PC12 cells
Lai Wang, Jingjing Cao, Zhenyu Shi, Wenjuan Fan, Hongliang Liu, Jinbo Deng, Jiexin Deng
Pages: 2764-2770 Published online on: 07 February 2018
Article
Amelioration of inflammatory responses by Socheongryong-Tang, a traditional herbal medicine, in RAW 264.7 cells and rats
Sang Mi Park, Tae Hoon Lee, Rongjie Zhao, Youn Sook Kim, Ji Yun Jung, Chung A. Park, Kyung Hwan Jegal, Sae Kwang Ku, Jae Kwang Kim, Chul Won Lee, Young Woo Kim, Il Je Cho, Won G. An, Sang Chan Kim
Pages: 2771-2783 Published online on: 06 February 2018
Article
Sitagliptin ameliorates diabetic nephropathy by blocking TGF-β1/Smad signaling pathway
Dongdong Wang, Guanying Zhang, Xiao Chen, Tong Wei, Chenxu Liu, Chun Chen, Yinhan Gong, Qunli Wei
Pages: 2784-2792 Published online on: 16 February 2018
Article
The antitumor activity screening of chemical constituents from Camellia nitidissima Chi
Xiaoying Hou, Hongzhi Du, Rui Yang, Jing Qi, Yue Huang, Shuyun Feng, Yao Wu, Sensen Lin, Zhixin Liu, Ai-Qun Jia, Shengtao Yuan, Li Sun
Pages: 2793-2801 Published online on: 16 February 2018
Article
Rhein protects against cerebral ischemic‑/reperfusion‑induced oxidative stress and apoptosis in rats
Qipeng Zhao, Xiaobo Wang, Ailing Chen, Xiuli Cheng, Guoxin Zhang, Jianmin Sun, Yunsheng Zhao, Yu Huang, Yafei Zhu
Pages: 2802-2812 Published online on: 13 February 2018
Article
Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification
Rong-Quan He, Pei-Rong Wu, Xue-Lian Xiang, Xia Yang, Hai-Wei Liang, Xiao-Hui Qiu, Li-Hua Yang, Zhi-Gang Peng, Gang Chen
Pages: 2813-2831 Published online on: 23 February 2018
Article
The PI3K/Akt/FOXO3a pathway regulates regeneration following spinal cord injury in adult rats through TNF-α and p27kip1 expression
Honghui Lu, Li-Hai Zhang, Lin Yang, Pei-Fu Tang
Pages: 2832-2838 Published online on: 06 February 2018
Article
17β-estradiol protects INS-1 insulinoma cells from mitophagy via G protein-coupled estrogen receptors and the PI3K/Akt signaling pathway
Liang Zhang, Yuyan Zhao, Lei Guo
Pages: 2839-2846 Published online on: 07 February 2018
Article
L‑histidine augments the oxidative damage against Gram‑negative bacteria by hydrogen peroxide
Tamiko Nagao, Haruyuki Nakayama‑Imaohji, Miad Elahi, Ayano Tada, Emika Toyonaga, Hisashi Yamasaki, Katsuichiro Okazaki, Hirokazu Miyoshi, Koichiro Tsuchiya, Tomomi Kuwahara
Pages: 2847-2854 Published online on: 07 February 2018
Article
α‑lipoic acid can greatly alleviate the toxic effect of AGES on SH‑SY5Y cells
Guifen Niu, Jianfei Guo, Yaqiang Tian, Kexiang Zhao, Jian Li, Qian Xiao
Pages: 2855-2864 Published online on: 08 February 2018
Article
Ang-(1-7) protects HUVECs from high glucose-induced injury and inflammation via inhibition of the JAK2/STAT3 pathway
Jianfang Chen, Wei Zhang, Qing Xu, Jihua Zhang, Wei Chen, Zhengrong Xu, Chaosheng Li, Zhenhua Wang, Yao Zhang, Yulan Zhen, Jianqiang Feng, Jun Chen, Jingfu Chen
Pages: 2865-2878 Published online on: 22 February 2018
Article
Zoledronate suppresses VEGF‑induced capillary tube formation and inhibits expression of interferon‑induced transmembrane protein‑1 in human umbilical vein endothelial cells
Beom Su Kim, Sun‑Sik Yang, Cheol‑Sang Kim, Jun Lee
Pages: 2879-2884 Published online on: 16 February 2018
Article
Changed immune and miRNA response in RAW264.7 cells infected with cell wall deficient mycobacterium tuberculosis
Zhengjun Yi, Kunshan Gao, Ruifang Li, Yurong Fu
Pages: 2885-2892 Published online on: 07 February 2018
Article
Downregulation of secreted clusterin potentiates the lethality of sorafenib in hepatocellular carcinoma in association with the inhibition of ERK1/2 signals
Jingtao Zhong, Xiaoming Yu, Xiaofeng Dong, Hong Lu, Wuyuan Zhou, Lei Li, Zhongchao Li, Pengfei Sun, Xuetao Shi
Pages: 2893-2900 Published online on: 06 February 2018
Article
Concomitant modulation of PTEN and Livin in gastric cancer treatment
Chun‑Lin Zhao, Sheng‑Na Han, Zhi‑Ju Wang, Shu‑Hui Wang, Guo‑Qiang Zhao, Xie‑Fu Zhang, Jia‑Xiang Wang
Pages: 2901-2908 Published online on: 08 February 2018
Article
Cav 1.2 and Cav 2.2 expression is regulated by different endogenous ghrelin levels in pancreatic acinar cells during acute pancreatitis
Jie Zhou, Mengbin Qin, Huilin Wang, Jiaping He, Hongzong Fu, Huirong Shi, Zhihai Liang, Guodu Tang
Pages: 2909-2916 Published online on: 13 February 2018
Article
BAG3 promotes the phenotypic transformation of primary rat vascular smooth muscle cells via TRAIL
Yao Fu, Ye Chang, Shuang Chen, Yuan Li, Yintao Chen, Guozhe Sun, Shasha Yu, Ning Ye, Chao Li, Yingxian Sun
Pages: 2917-2926 Published online on: 14 February 2018
Article
Effect of placental sex hormone-binding globulin single nucleotide polymorphism rs6259 on protein and function in gestational diabetes mellitus
Xuan Zhang, Lei Sun, Zhen Jin
Pages: 2927-2934 Published online on: 16 February 2018
Article
The transcription factor cMaf is targeted by mTOR, and regulates the inflammatory response via the TLR4 signaling pathway
Yan Wang, Caifu Luan, Guili Zhang, Chengming Sun
Pages: 2935-2942 Published online on: 23 February 2018
Article
The expression and activation of sex steroid receptors in the preeclamptic placenta
Mee‑Na Park, Kyung‑Hee Park, Jae‑Eon Lee, Ye Young Shin, Sung‑Min An, Seong Soo Kang, Wan‑Seob Cho, Beum‑Soo An, Seung Chul Kim
Pages: 2943-2951 Published online on: 08 February 2018
Article
Euphorbia supina extract results in inhibition of high‑fat‑diet‑induced obesity in mice
Sarmila Nepali, Do‑Kuk Kim, Hoon‑Yeon Lee, Hyeon‑Hui Ki, Bo‑Ram Kim, Sung‑Woo Hwang, Min Park, Dae‑Ki Kim, Young‑Mi Lee
Pages: 2952-2960 Published online on: 16 February 2018
Article
Interplay between the NF‑κB and hedgehog signaling pathways predicts prognosis in esophageal squamous cell carcinoma following neoadjuvant chemoradiotherapy
Lingyun Wei, Nang Yan, Lei Sun, Chuanen Bao, Demin Li
Pages: 2961-2967 Published online on: 01 February 2018
Article
The effects of TRAF6 on proliferation, apoptosis and invasion in osteosarcoma are regulated by miR-124
Qingbing Meng, Wensheng Zhang, Xingli Xu, Jian Li, Hongxin Mu, Xiaolan Liu, Ling Qin, Xiaoqi Zhu, Minqian Zheng
Pages: 2968-2976 Published online on: 05 February 2018
Article
GLP‑1R agonists ameliorate peripheral nerve dysfunction and inflammation via p38 MAPK/NF‑κB signaling pathways in streptozotocin‑induced diabetic rats
Jingjing Ma, Min Shi, Xiangcheng Zhang, Xiaoning Liu, Juan Chen, Ridong Zhang, Xingzhou Wang, Hong Zhang
Pages: 2977-2985 Published online on: 23 February 2018
Article
Homeobox protein MSX1 inhibits the growth and metastasis of breast cancer cells and is frequently silenced by promoter methylation
Yujuan Yue, Ying Yuan, Lili Li, Jiangxia Fan, Chen Li, Weiyan Peng, Guosheng Ren
Pages: 2986-2996 Published online on: 07 February 2018
Article
Mitochondrial protective mechanism of simvastatin protects against amyloid β peptide-induced injury in SH-SY5Y cells
Yunzi Li, Qian Liu, Jing Sun, Jin Wang, Xinfeng Liu, Jing Gao
Pages: 2997-3005 Published online on: 05 February 2018
Article
Metabolic changes associated with papillary thyroid carcinoma: A nuclear magnetic resonance-based metabolomics study
Yanyun Li, Minjian Chen, Cuiping Liu, Yankai Xia, Bo Xu, Yanhui Hu, Ting Chen, Meiping Shen, Wei Tang
Pages: 3006-3014 Published online on: 16 February 2018
Article
Adenovirus-mediated P311 ameliorates renal fibrosis through inhibition of epithelial-mesenchymal transition via TGF-β1-Smad-ILK pathway in unilateral ureteral obstruction rats
Fang-Hua Qi, Ping-Ping Cai, Xiang Liu, Guo-Min Si
Pages: 3015-3023 Published online on: 12 February 2018
Article
Fingerprint analysis and pharmacological evaluation of Ailanthus altissima
Qiaoyan He, Huimin Xiao, Jie Li, Yang Liu, Min Jia, Fang Wang, Ya Zhang, Wen Wang, Siwang Wang
Pages: 3024-3032 Published online on: 14 February 2018
Article
Madecassoside activates anti‑neuroinflammatory mechanisms by inhibiting lipopolysaccharide‑induced microglial inflammation
Andrew Octavian Sasmita, Anna Pick Kiong Ling, Kenny Gah Leong Voon, Rhun Yian Koh, Ying Pei Wong
Pages: 3033-3040 Published online on: 09 February 2018
Article
UVB induces apoptosis via downregulation of CALML3-dependent JNK1/2 and ERK1/2 pathways in cataract
Yin Jia, Qin Qin, Chao‑Ping Fang, Wei Shen, Ting‑Ting Sun, Yuan‑Lan Huang, Wen‑Jie Li, An‑Mei Deng
Pages: 3041-3050 Published online on: 09 February 2018
Article
Ferroptosis is associated with oxygen-glucose deprivation/reoxygenation-induced Sertoli cell death
Li Li, Yu Hao, Yu Zhao, Huijuan Wang, Xiujun Zhao, Yan Jiang, Fulu Gao
Pages: 3051-3062 Published online on: 07 February 2018
Article
Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7
Xin‑Long Wang, Yuan‑Yuan Zhao, Li Sun, Yu Shi, Zhu‑Qian Li, Xiang‑Dong Zhao, Chang‑Gen Xu, Hong‑Ge Ji, Mei Wang, Wen‑Rong Xu, Wei Zhu
Pages: 3063-3072 Published online on: 16 February 2018
Article
Black rice (Oryza sativa L.) extract modulates ultraviolet-induced expression of matrix metalloproteinases and procollagen in a skin cell model
Mira Han, Jung‑Soo Bae, Jae‑Jun Ban, Hee Soon Shin, Dong Hun Lee, Jin Ho Chung
Pages: 3073-3080 Published online on: 22 February 2018
Article
RP105 protects PC12 cells from oxygen‑glucose deprivation/reoxygenation injury via activation of the PI3K/AKT signaling pathway
Yanpeng Sun, Lu Liu, Jiang Yuan, Qiang Sun, Na Wang, Yunfu Wang
Pages: 3081-3089 Published online on: 12 February 2018
Article
