Journal Articles

Open Access

Antitumor effects and mechanisms of pyropheophorbide‑α methyl ester‑mediated photodynamic therapy on the human osteosarcoma cell line MG‑63

Yanyang Chen, Hang Yin, Yong Tao, Shenxi Zhong, Haoyang Yu, Jianxiao Li, Zhibiao Bai, Yunsheng Ou

Pages: 971-982 Published online on: 10 February 2020
Open Access

Tanshinone I induces apoptosis and protective autophagy in human glioblastoma cells via a reactive oxygen species‑dependent pathway

Shangguan Jian, Liang Chen, Lian Minxue, Che Hongmin, Tang Ronghua, Fan Xiaoxuan, Zhang Binbin, Guo Shiwen

Pages: 983-992 Published online on: 13 February 2020
Open Access

Chromomycin A3 suppresses cholangiocarcinoma growth by induction of S phase cell cycle arrest and suppression of Sp1‑related anti‑apoptotic proteins

Paksiree Saranaruk, Ryusho Kariya, Gunya Sittithumcharee, Parichart Boueroy, Thidarut Boonmars, Kanlayanee Sawanyawisuth, Chaisiri Wongkham, Sopit Wongkham, Seiji Okada, Kulthida Vaeteewoottacharn

Pages: 1005-1016 Published online on: 29 January 2020
Open Access

Role of the p53‑TRPM1/miR‑211‑MMP9 axis in UVB‑induced human melanocyte migration and its potential in repigmentation

Mengyun Su, Fang Miao, Shan Jiang, Ying Shi, Longfei Luo, Xiaolei He, Jing Wan, Shizheng Xu, Tie‑Chi Lei

Pages: 1017-1026 Published online on: 27 January 2020
Open Access

HIF‑1α attenuates neuronal apoptosis by upregulating EPO expression following cerebral ischemia‑reperfusion injury in a rat MCAO model

Jun Li, Tao Tao, Jian Xu, Zhi Liu, Zhehua Zou, Minglu Jin

Pages: 1027-1036 Published online on: 28 January 2020
Open Access

Rab22a is a novel prognostic marker for cell progression in breast cancer

Miao He, Leihua Shen, Chengwei Jiang, Ge Gao, Keren Wang, Yan Jiao, Liang Sun, Yingnan Cui, Zirui Ke, Zhaoying Yang

Pages: 1037-1046 Published online on: 05 February 2020
Open Access

Unraveling the genetic causes in large pedigrees with gout by whole‑exome sequencing

Xiaoru Xia, Jing Jin, Zhen‑Ji Chen, Zhenni Zhou, Hui Chen, Chunwu Zhang, Linhua Zhang, Li Sun

Pages: 1047-1058 Published online on: 13 February 2020
Open Access

Scutellarein inhibits the development of colon cancer via CDC4‑mediated RAGE ubiquitination

Yuanzhi Li, Jundong Wang, Sen Zhong, Jun Li, Weiliang Du

Pages: 1059-1072 Published online on: 10 February 2020
Open Access

SNAIL expression correlates with the translocation of syndecan‑1 intracellular domain into the nucleus in prostate cancer cell lines

Nancy Farfán, Octavio Orellana‑Serradell, Daniela Herrera, Dominique Chrzanowsky, Paulina Cubillos, Gabriel Marín, Antonio Antonio García De Herreros, Enrique A. Castellón, Héctor R. Contreras

Pages: 1073-1080 Published online on: 05 February 2020
Open Access

Pirfenidone attenuates homocysteine‑induced apoptosis by regulating the connexin 43 pathway in H9C2 cells

Kai Chen, Ling Chen, Yuanshuo Ouyang, Liang Zhang, Xinzhi Li, Li Li, Junqiang Si, Li Wang, Ketao Ma

Pages: 1081-1090 Published online on: 13 February 2020
Open Access

MicroRNA‑449a regulates the progression of brain aging by targeting SCN2B in SAMP8 mice

Ya‑Xin Tan, Ying Hong, Shui Jiang, Min‑Nan Lu, Shan Li, Bo Chen, Li Zhang, Tao Hu, Rui Mao, Rong Mei, Yan‑Bin Xiyang

Pages: 1091-1102 Published online on: 13 February 2020
Open Access

A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang‑Qing Wu, Qi‑Bin Xu, Wen‑Yan Sheng, Lin‑Ya Su, Li‑Wei Zhu

Pages: 1103-1111 Published online on: 28 January 2020
Open Access

Adiponectin inhibits the differentiation and maturation of osteoclasts via the mTOR pathway in multiple myeloma

Zhaoyun Liu, Hui Liu, Yanqi Li, Yangyang Wang, Rui Xing, Fu Mi, Chenhuan Xiang, Rong Fu

Pages: 1112-1120 Published online on: 24 January 2020
Open Access

CYP4A11 is involved in the development of nonalcoholic fatty liver disease via ROS‑induced lipid peroxidation and inflammation

Huifang Gao, Yaru Cao, Hongguang Xia, Xiangyu Zhu, Yong Jin

Pages: 1121-1129 Published online on: 28 January 2020
Open Access

Lactobacillus salivarius BP121 prevents cisplatin‑induced acute kidney injury by inhibition of uremic toxins such as indoxyl sulfate and p‑cresol sulfate via alleviating dysbiosis

Tae‑Hee Lee, Dongsun Park, Yang Ji Kim, Isaac Lee, Suae Kim, Chang‑Taek Oh, Joem‑Yong Kim, Jihyun Yang, Sang‑Kyung Jo

Pages: 1130-1140 Published online on: 10 February 2020
Open Access

Specific microRNAs are involved in the reno‑protective effects of sevoflurane preconditioning and ischemic preconditioning against ischemia reperfusion injury in rats

Makiko Yamamoto, Tomonori Morita, Masashi Ishikawa, Atsuhiro Sakamoto

Pages: 1141-1149 Published online on: 27 January 2020
Open Access

HDAC inhibitor sodium butyrate prevents allergic rhinitis and alters lncRNA and mRNA expression profiles in the nasal mucosa of mice

Jie Wang, Mu Cui, Fei Sun, Ke Zhou, Bei Fan, Jian‑Hua Qiu, Fu‑Quan Chen

Pages: 1150-1162 Published online on: 05 February 2020
Open Access

Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG

Yaojia Cheng, Qiuping Lu, Nannan Shi, Qiongyan Zhou, Jingjing Rong, Liyun Li, Li Wang, Chen Liu

Pages: 1163-1175 Published online on: 05 February 2020
Open Access

Exogenous carbon monoxide protects against mitochondrial DNA‑induced hippocampal pyroptosis in a model of hemorrhagic shock and resuscitation

Lan Fu, Dong‑Xue Zhang, Li‑Min Zhang, Yan‑Cheng Song, Feng‑Hai Liu, Yan Li, Xu‑Peng Wang, Wei‑Chao Zheng, Xiao‑Dong Wang, Chun‑Xiao Gui, Xiang‑Jun Kong, Li‑Qing Kang

Pages: 1176-1186 Published online on: 07 February 2020

Overexpression of IFIT2 inhibits the proliferation of chronic myeloid leukemia cells by regulating the BCR‑ABL/AKT/mTOR pathway

Zhanglin Zhang, Na Li, Shuyuan Liu, Mei Jiang, Jinghua Wan, Yonglu Zhang, Lagen Wan, Caifeng Xie, Aiping Le

Pages: 1187-1194 Published online on: 13 February 2020

Echinacoside‑induced nitric oxide production in endothelial cells: Roles of androgen receptor and the PI3K‑Akt pathway

Li Gu, Danhong Lian, Yimei Zheng, Wei Zhou, Jinlei Gu, Xin Liu

Pages: 1195-1202 Published online on: 27 January 2020

Expression and clinical significance of circular RNAs hsa_circ_0000175 and hsa_circ_0008410 in peripheral blood mononuclear cells from patients with rheumatoid arthritis

Qing Luo, Lulu Zeng, Lingbing Zeng, Jiayue Rao, Lu Zhang, Yang Guo, Zikun Huang, Junming Li

Pages: 1203-1212 Published online on: 13 February 2020
Open Access

Hesperetin reverses P‑glycoprotein‑mediated cisplatin resistance in DDP‑resistant human lung cancer cells via modulation of the nuclear factor‑κB signaling pathway

Wencui Kong, Xiaoming Ling, Ying Chen, Xiaoli Wu, Zhongquan Zhao, Wenwu Wang, Shuiliang Wang, Guoxiang Lai, Zongyang Yu

Pages: 1213-1224 Published online on: 05 February 2020

Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes Corrigendum in /10.3892/ijmm.2020.4786

Yubiao Zhang, Weisong Cai, Guangtao Han, Siqi Zhou, Jianping Li, Mao Chen, Haohuan Li

Pages: 1225-1236 Published online on: 06 February 2020

Exendin‑4 inhibits lipotoxicity‑induced oxidative stress in β‑cells by inhibiting the activation of TLR4/NF‑κB signaling pathway

Ximei Shen, Liufen Luo, Meng Yang, Yuxi Lin, Jing Li, Liyong Yang

Pages: 1237-1249 Published online on: 06 February 2020

Cordyceps sinensis attenuates HBx‑induced cell apoptosis in HK‑2 cells through suppressing the PI3K/Akt pathway

Ping He, Jing Lei, Jia‑Ning Miao, Di Wu, Cheng Wang

Pages: 1261-1269 Published online on: 14 February 2020
Open Access

[Retracted] Diagnostic and prognostic value of contrast‑enhanced ultrasound combined with diffusion‑weighted magnetic resonance imaging in different subtypes of breast cancer

Gui‑Feng Liu, Zong‑Qiang Wang, Shu‑Hua Zhang, Xue‑Feng Li, Lin Liu, Ying‑Ying Miao, Shao‑Nan Yu

Pages: 1270-1270 Published online on: 04 February 2020
Journal Cover

April-2020
Volume 45 Issue 4

Print ISSN: 1107-3756
Online ISSN: 1791-244X

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