Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Molecular Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1107-3756 Online ISSN: 1791-244X
presentation
International Journal of Molecular Medicine

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

  • Selected Issue
  • Current Issue
  • Forthcoming Issue
  • Special Issues
    • Open Special Issues
    • About Special Issues
  • Trending Articles
    • Most Read
    • Most Cited (Dimensions)
      • Past Two Years
      • Total
    • Most Cited (Crossref)
      • Past Year
      • Total
    • Social Media
      • Past Month
      • Past Year
      • Total
  • Information
    • Information for Authors
    • Contact
    • Editorial Policies
    • Editorial Academy
    • Aims and Scope
    • Abstracting and Indexing
    • Bibliographic Information
  • Archive
Journal Cover
April-2021 Volume 47 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

COVID‑19 and SARS‑CoV‑2 host cell entry mediators: Expression profiling of TMRSS4 in health and disease

Periklis Katopodis, Rachel Kerslake, Julie Davies, Harpal S. Randeva, Kamaljit Chatha, Marcia Hall, Demetrios A. Spandidos, Vladimir Anikin, Andreas Polychronis, Jan L. Robertus, Ioannis Kyrou, Emmanouil Karteris
Article Number: 64
Published online on: 26 February 2021

  • View Full Article Download
Article Open Access

Peptide Szeto‑Schiller 31 ameliorates doxorubicin‑induced cardiotoxicity by inhibiting the activation of the p38 MAPK signaling pathway

Li Zhang, Mengwen Feng, Xuejun Wang, Hao Zhang, Jingjing Ding, Zijie Cheng, Lingmei Qian
Article Number: 63
Published online on: 25 February 2021

  • View Full Article Download
Article Open Access

Ginkgolide C attenuates lipopolysaccharide‑induced acute lung injury by inhibiting inflammation via regulating the CD40/NF‑κB signaling pathway

Rui Zhang, Nan Guo, Genquan Yan, Qian Wang, Tiantian Gao, Baoke Zhang, Ning Hou
Article Number: 62
Published online on: 24 February 2021

  • View Full Article Download
Article Open Access

miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease Corrigendum in /10.3892/ijmm.2025.5565

Xinrong Li, Wenwen Si, Zhan Li, Ye Tian, Xuelei Liu, Shanyu Ye, Zifeng Huang, Yichun Ji, Caiping Zhao, Xiaoqian Hao, Dongfeng Chen, Meiling Zhu
Article Number: 61
Published online on: 23 February 2021

  • View Full Article Download
Article Open Access

Iron overload in aging Bmp6‑/‑ mice induces exocrine pancreatic injury and fibrosis due to acinar cell loss

Martina Pauk, Vera Kufner, Viktorija Rumenovic, Ivo Dumic‑Cule, Vladimir Farkas, Milan Milosevic, Tatjana Bordukalo‑Niksic, Slobodan Vukicevic
Article Number: 60
Published online on: 19 February 2021

  • View Full Article Download
Article Open Access

5‑Nitro‑2‑(3‑phenylpropylamino) benzoic acid induces apoptosis of human lens epithelial cells via reactive oxygen species and endoplasmic reticulum stress through the mitochondrial apoptosis pathway

Lingzhi Niu, Xin Liu, Jing Zhao, Yuanping Wang, Yanxia Li, Ke Li, Yingjian Sun, Yajuan Zheng
Article Number: 59
Published online on: 18 February 2021

  • View Full Article Download
Correction Open Access

[Corrigendum] TUSC8 inhibits the development of osteosarcoma by sponging miR‑197‑3p and targeting EHD2

Hongwu Fan, Tong Liu, Hao Tian, Shanyong Zhang
Article Number: 58
Published online on: 18 February 2021

  • View Full Article Download
Article Open Access

Human osteoclasts/osteoblasts 3D dynamic co‑culture system to study the beneficial effects of glucosamine on bone microenvironment

Elisabetta Lambertini, Letizia Penolazzi, Assunta Pandolfi, Domitilla Mandatori, Vincenzo Sollazzo, Roberta Piva
Article Number: 57
Published online on: 17 February 2021

  • View Full Article Download
Article

Identification of the internal ribosome entry sites in the 5'‑untranslated region of the c‑fos gene

Hui Li, Yuhang Chen, Junshi Zhang, Yongquan Lin, Zhilong Yang, Juan Tan, Wentao Qiao
Article Number: 56
Published online on: 15 February 2021

  • View Full Article Download
Review Open Access

Role and clinical significance of TGF‑β1 and TGF‑βR1 in malignant tumors (Review)

Junmin Wang, Hongjiao Xiang, Yifei Lu, Tao Wu
Article Number: 55
Published online on: 15 February 2021

  • View Full Article Download
Article Open Access

Long non‑coding RNA KCNQ1OT1 promotes nasopharyngeal carcinoma cell cisplatin resistance via the miR‑454/USP47 axis Retraction in /10.3892/ijmm.2024.5355

Feng Yuan, Zhiping Lou, Zhifeng Zhou, Xiaojun Yan
Article Number: 54
Published online on: 11 February 2021

  • View Full Article Download
Article Open Access

PCSK9 mediates the oxidative low‑density lipoprotein‑induced pyroptosis of vascular endothelial cells via the UQCRC1/ROS pathway

Junfa Zeng, Jun Tao, Linzhen Xi, Zuo Wang, Lushan Liu
Article Number: 53
Published online on: 11 February 2021

  • View Full Article Download
Article Open Access

Carthamin yellow improves cerebral ischemia‑reperfusion injury by attenuating inflammation and ferroptosis in rats

Huihui Guo, Lili Zhu, Pingping Tang, Dong Chen, Yancai Li, Jianbing Li, Chao Bao
Article Number: 52
Published online on: 11 February 2021

  • View Full Article Download
Article Open Access

Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway

Yuqi Zhou, Xiangyong Li, Min Ye
Article Number: 51
Published online on: 10 February 2021

  • View Full Article Download
Article Open Access

Structural analysis and macrophage activation of a novel β‑glucan isolated from Cantharellus cibarius

Yunhe Qu, Xiaolin Zhao, Huijun Guo, Yue Meng, Yumeng Wang, Yifa Zhou, Lin Sun
Article Number: 50
Published online on: 10 February 2021

  • View Full Article Download
Article Open Access

Helichrysetin and TNF‑α synergistically promote apoptosis by inhibiting overactivation of the NF‑κB and EGFR signaling pathways in HeLa and T98G cells

Zhiying Wang, Xiaohui Liang, Aizhen Xiong, Lili Ding, Wei Li, Li Yang, Xiaojun Wu, Hailian Shi, Yue Zhou, Zhengtao Wang
Article Number: 49
Published online on: 10 February 2021

  • View Full Article Download
Article Open Access

Apoptotic mechanism activated by blue light and cisplatinum in cutaneous squamous cell carcinoma cells

Maria Fiorella Tartaglione, María Eléxpuru Zabaleta, Raffaella Lazzarini, Francesco Piva, Elena Marinelli Busilacchi, Antonella Poloni, Caterina Ledda, Venerando Rapisarda, Lory Santarelli, Massimo Bracci
Article Number: 48
Published online on: 09 February 2021

  • View Full Article Download
Review Open Access

Pineal hormone melatonin as an adjuvant treatment for COVID‑19 (Review)

Marilena Vlachou, Angeliki Siamidi, Aikaterini Dedeloudi, Sofia K. Konstantinidou, Ioannis P. Papanastasiou
Article Number: 47
Published online on: 09 February 2021

  • View Full Article Download
Article Open Access

Long non‑coding RNA LINC01006 exhibits oncogenic properties in cervical cancer by functioning as a molecular sponge for microRNA‑28‑5p and increasing PAK2 expression

Libin Tian, Feng Han, Jing Yang, Xiaoqiong Ming, Lili Chen
Article Number: 46
Published online on: 09 February 2021

  • View Full Article Download
Article

Curcumin protects BEAS‑2B cells from PM2.5‑induced oxidative stress and inflammation by activating NRF2/antioxidant response element pathways

Shuo Yang, Xiao-Long Huang, Jin Chen, Li-Na Mao, Xu Liu, Wen-Sheng Yuan, Xiao-Jie Wu, Guang-Wei Luo
Article Number: 45
Published online on: 08 February 2021

  • View Full Article Download
Article

Long non‑coding RNA ASAP1‑IT1 suppresses ovarian cancer progression by regulating Hippo/YAP signaling

Ke Wang, Yu-Bo Hu, Ye Zhao, Cong Ye
Article Number: 44
Published online on: 08 February 2021

  • View Full Article Download
Review Open Access

Determining available strategies for prevention and therapy: Exploring COVID‑19 from the perspective of ACE2 (Review)

Liyang Cai, Xi Guo, Yuchen Cao, Peixi Ying, Libing Hong, Yuxi Zhang, Guoguo Yi, Min Fu
Article Number: 43
Published online on: 08 February 2021

  • View Full Article Download
Review

Involvement of non‑coding RNAs in the pathogenesis of myocardial ischemia/reperfusion injury (Review)

Qi Li, Zhuqing Li, Zhixing Fan, Ying Yang, Chengzhi Lu
Article Number: 42
Published online on: 05 February 2021

  • View Full Article Download
Article Open Access

Kaiso regulates osteoblast differentiation and mineralization via the Itga10/PI3K/AKT signaling pathway

Wenwen Tong, Jia Li, Xinzhe Feng, Chen Wang, Yihong Xu, Chongru He, Weidong Xu
Article Number: 41
Published online on: 05 February 2021

  • View Full Article Download
Article Open Access

CircUSP36 knockdown alleviates oxidized low‑density lipoprotein‑induced cell injury and inflammatory responses in human umbilical vein endothelial cells via the miR‑20a‑5p/ROCK2 axis

Jun Miao, Bo Wang, Ran Shao, Yan Wang
Article Number: 40
Published online on: 05 February 2021

  • View Full Article Download
Article Open Access

Quercetin reverses TNF‑α induced osteogenic damage to human periodontal ligament stem cells by suppressing the NF‑κB/NLRP3 inflammasome pathway

Wenjing Zhang, Linglu Jia, Bin Zhao, Yixuan Xiong, Ya-Nan Wang, Jin Liang, Xin Xu
Article Number: 39
Published online on: 04 February 2021

  • View Full Article Download
Review Open Access

The role of the Golgi apparatus in disease (Review)

Jianyang Liu, Yan Huang, Ting Li, Zheng Jiang, Liuwang Zeng, Zhiping Hu
Article Number: 38
Published online on: 04 February 2021

  • View Full Article Download
Article Open Access

Bromamine T, a stable active bromine compound, prevents the LPS‑induced inflammatory response

Stella Baliou, Michael Sofopoulos, Maria Goulielmaki, Demetrios A. Spandidos, Petros Ioannou, Anthony M. Kyriakopoulos, Vassilios Zoumpourlis
Article Number: 37
Published online on: 03 February 2021

  • View Full Article Download
Article Open Access

Upregulated miR‑411‑5p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma

Chi Zhang, Hongfei Wang, Miao Deng, Lihong He, Fan Ping, Yuan He, Zhaona Fan, Bin Cheng, Juan Xia
Article Number: 36
Published online on: 03 February 2021

  • View Full Article Download
Article Open Access

Downregulation of lncRNA MIR181A2HG by high glucose impairs vascular endothelial cell proliferation and migration through the dysregulation of the miRNAs/AKT2 axis

Shaohua Wang, Bin Zheng, Hongye Zhao, Yongjun Li, Xinhua Zhang, Jinkun Wen
Article Number: 35
Published online on: 02 February 2021

  • View Full Article Download
Article Open Access

Hydrogen sulfide inhibits endoplasmic reticulum stress through the GRP78/mTOR pathway in rat chondrocytes subjected to oxidative stress

Jianjun Wu, Fan Yang, Xin Zhang, Guanghua Chen, Jilong Zou, Li Yin, Dawei Yang
Article Number: 34
Published online on: 02 February 2021

  • View Full Article Download
Article Open Access

Long non‑coding RNA LINC00491 promotes proliferation and inhibits apoptosis in esophageal squamous cell carcinoma

Hui Ye, Sachin Mulmi Shrestha, Jie Zhu, Yan Ding, Ruihua Shi
Article Number: 33
Published online on: 02 February 2021

  • View Full Article Download
Review Open Access

Potential immunomodulatory effects of vitamin D in the prevention of severe coronavirus disease 2019: An ally for Latin America (Review)

Francisco Javier Turrubiates‑Hernández, Gabriela Athziri Sánchez‑Zuno, Guillermo González‑Estevez, Jorge Hernández‑Bello, Gabriela Macedo‑Ojeda, José Francisco Muñoz‑Valle
Article Number: 32
Published online on: 01 February 2021

  • View Full Article Download
Review Open Access

Nosocomial infection of COVID‑19: A new challenge for healthcare professionals (Review)

Qiu Du, Dingding Zhang, Weimin Hu, Xuefei Li, Qiongrong Xia, Taishen Wen, Haiping Jia
Article Number: 31
Published online on: 01 February 2021

  • View Full Article Download
Article Open Access

Paris saponin H inhibits the proliferation of glioma cells through the A1 and A3 adenosine receptor‑mediated pathway

Linlin Bi, Yang Liu, Qian Yang, Xuanxuan Zhou, Hua Li, Jie Li, Yunyang Lu, Haifeng Tang
Article Number: 30
Published online on: 01 February 2021

  • View Full Article Download
Journal Cover
February-2026 Volume 57 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

  • View Full Article Download
Review Open Access

Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

  • View Full Article Download
Review Open Access

Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

  • View Full Article Download
Review Open Access

Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

  • View Full Article Download
Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

  • View Full Article Download
Review Open Access

A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

  • View Full Article Download
Review Open Access

Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

  • View Full Article Download
Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

  • View Full Article Download
Review Open Access

Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

  • View Full Article Download
Review Open Access

Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

  • View Full Article Download
Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

  • View Full Article Download
Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

  • View Full Article Download
Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

  • View Full Article Download
Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

  • View Full Article Download
Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

  • View Full Article Download
Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

  • View Full Article Download
Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

  • View Full Article Download
Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

  • View Full Article Download
Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

  • Purchase Full Text Article Purchase Download
Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

  • View Full Article Download
Journal Cover
March-2026 Volume 57 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

  • Download
Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

  • Download
Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

  • Download
Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

  • Download
Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

  • Download
Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

  • Download
Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

  • Download
Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

  • Purchase Download
Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

  • Download
Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

  • Download
Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

  • Download
Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

  • Download
Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

  • View Full Article Download
Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

  • View Full Article Download
Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

  • View Full Article Download
Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

  • View Full Article Download
Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

  • View Full Article Download
Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

  • View Full Article Download
Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

  • View Full Article Download
Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

  • View Full Article Download
Select a topic from the Information tab...
Special issues coming soon...
No data
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team