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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2018 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Identification of genes and pathways associated with MDR in MCF-7/MDR breast cancer cells by RNA-seq analysis

Minlan Yang, Hairi Li, Yanru Li, Yang Ruan, Chengshi Quan
Pages: 6211-6226
Published online on: 07 March 2018

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Article Open Access

Identification of potential genes and miRNAs associated with sepsis based on microarray analysis

Yin Li, Fengxia Zhang, Yan Cong, Yun Zhao
Pages: 6227-6234
Published online on: 01 March 2018

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Article Open Access

Eruca sativa seed extract: A novel natural product able to counteract neuroinflammation

Agnese Gugliandolo, Sabrina Giacoppo, Marcello Ficicchia, Angelo Aliquò, Placido Bramanti, Emanuela Mazzon
Pages: 6235-6244
Published online on: 07 March 2018

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Article Open Access

Therapeutic effects of antimicrobial peptide on malignant ascites in a mouse model

Li‑Jie Xia, Yan‑Ling Wu, Ji Ma, Fu‑Chun Zhang
Pages: 6245-6252
Published online on: 07 March 2018

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Article Open Access

miR‑205‑5p/PTK7 axis is involved in the proliferation, migration and invasion of colorectal cancer cells

Shuo Chen, Yan Wang, Yinan Su, Lin Zhang, Mingqing Zhang, Xueqing Li, Juan Wang, Xipeng Zhang
Pages: 6253-6260
Published online on: 28 February 2018

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Article Open Access

Metabolomics analysis reveals an effect of homocysteine on arachidonic acid and linoleic acid metabolism pathway

Bin Li, Guangqiang Gao, Wanying Zhang, Bowen Li, Chun Yang, Xiaofeng Jiang, Yaping Tian, Hongyan Liang
Pages: 6261-6268
Published online on: 27 February 2018

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Article Open Access

Ginsenoside Rg1 ameliorates testicular senescence changes in D‑gal‑induced aging mice via anti‑inflammatory and antioxidative mechanisms

Zi‑Ling Wang, Lin‑Bo Chen, Zhu Qiu, Xiong‑Bin Chen, Ying Liu, Jing Li, Lu Wang, Ya‑Ping Wang
Pages: 6269-6276
Published online on: 01 March 2018

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Article Open Access

BMP7 regulates lung fibroblast proliferation in newborn rats with bronchopulmonary dysplasia

Yanli Sun, Jianhua Fu, Xindong Xue, Haiping Yang, Linlin Wu
Pages: 6277-6284
Published online on: 07 March 2018

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Article Open Access

Upregulation of miR-614 promotes proliferation and inhibits apoptosis in ovarian cancer by suppressing PPP2R2A expression

Jing Zhang, Dongdong Gao, Hui Zhang
Pages: 6285-6292
Published online on: 09 March 2018

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Article Open Access

ML-7 attenuates airway inflammation and remodeling via inhibiting the secretion of Th2 cytokines in mice model of asthma

Chuanjun Huang, Zewen Zhang, Liuxin Wang, Ju Liu, Xiaodan Gong, Caiqing Zhang
Pages: 6293-6300
Published online on: 06 March 2018

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Article Open Access

MicroRNA-214-5p/TGF-β/Smad2 signaling alters adipogenic differentiation of bone marrow stem cells in postmenopausal osteoporosis

Jiang Qiu, Gang Huang, Ning Na, Lizhong Chen
Pages: 6301-6310
Published online on: 09 March 2018

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Article Open Access

Local intra‑articular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis model

Shuang Deng, Jian‑Lin Zhou, Hao Peng, Hong‑Song Fang, Feng Liu, Jin‑Qing Weng
Pages: 6311-6318
Published online on: 28 February 2018

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Article Open Access

MicroRNA-378 enhances migration and invasion in cervical cancer by directly targeting autophagy-related protein 12 Corrigendum in /10.3892/mmr.2024.13366

Dongmei Tan, Chao Zhou, Sai Han, Xuetao Hou, Shufang Kang, Youzhong Zhang
Pages: 6319-6326
Published online on: 27 February 2018

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Article Open Access

Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats

Xiao‑Jing Wu, Hui‑Min Liu, Xue‑Min Song, Bo Zhao, Yan Leng, E‑You Wang, Li‑Ying Zhan, Qing‑Tao Meng, Zhong‑Yuan Xia
Pages: 6327-6336
Published online on: 27 February 2018

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Article Open Access

Transdermal estrogen gel and oral aspirin combination therapy improves fertility prognosis via the promotion of endometrial receptivity in moderate to severe intrauterine adhesion

Yugang Chi, Ping He, Li Lei, Yi Lan, Jianguo Hu, Ying Meng, Lina Hu
Pages: 6337-6344
Published online on: 06 March 2018

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Article Open Access

Pathway- and clinical-factor-based risk model predicts the prognosis of patients with gastric cancer

Junchi Yang, Lumin Bo, Ting Han, Dan Ding, Mingming Nie, Kai Yin
Pages: 6345-6356
Published online on: 09 March 2018

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Article Open Access

Kupffer cell depletion by gadolinium chloride aggravates liver injury after brain death in rats

Rongtao Zhu, Weizhi Guo, Hongbo Fang, Shengli Cao, Bing Yan, Sanyang Chen, Kaiming Zhang, Shuijun Zhang
Pages: 6357-6362
Published online on: 27 February 2018

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Article Open Access

Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Pages: 6363-6370
Published online on: 28 February 2018

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Article Open Access

Identification of the key genes associated with neuropathic pain

Huan Liu, Tianjiao Xia, Fangxia Xu, Zhengliang Ma, Xiaoping Gu
Pages: 6371-6378
Published online on: 09 March 2018

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Article Open Access

Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Pages: 6379-6386
Published online on: 09 March 2018

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Article Open Access

Identification of COL4A1 as a potential gene conferring trastuzumab resistance in gastric cancer based on bioinformatics analysis

Ru Huang, Wenchao Gu, Bin Sun, Lei Gao
Pages: 6387-6396
Published online on: 01 March 2018

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Article Open Access

miR‑3147 serves as an oncomiR in vulvar squamous cell cancer via Smad4 suppression

Xiu‑Hua Yang, Feng Guo
Pages: 6397-6404
Published online on: 07 March 2018

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Article Open Access

Downregulation of the long non-coding RNA ZFAS1 is associated with cell proliferation, migration and invasion in breast cancer

Shulin Fan, Chunni Fan, Ning Liu, Keke Huang, Xuedong Fang, Keren Wang
Pages: 6405-6412
Published online on: 09 March 2018

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Article Open Access

Expression profiles of long noncoding RNAs and mRNAs in post-cardiac arrest rat brains

Rong Liu, Xiaoxing Liao, Xin Li, Hongyan Wei, Qing Liang, Zuopeng Zhang, Meixian Yin, Xiaoyun Zeng, Zijing Liang, Chunlin Hu
Pages: 6413-6424
Published online on: 07 March 2018

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Article Open Access

Identification of differentially expressed genes and biological pathways in bladder cancer

Fucai Tang, Zhaohui He, Hanqi Lei, Yuehan Chen, Zechao Lu, Guohua Zeng, Hangtao Wang
Pages: 6425-6434
Published online on: 09 March 2018

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Article Open Access

Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR

Stavros Sifakis, Vasilis P. Androutsopoulos, Artemis Pontikaki, Alexis Velegrakis, George I. Papaioannou, Ourania Koukoura, Demetrios A. Spandidos, Nikos Papantoniou
Pages: 6435-6440
Published online on: 09 March 2018

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Article Open Access

Atorvastatin prevents glomerular extracellular matrix formation by interfering with the PKC signaling pathway

Yan‑Hua Xiao, Xiao‑Yun He, Qing Han, Fan Yang, Su‑Xian Zhou
Pages: 6441-6448
Published online on: 09 March 2018

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Article Open Access

Screening for key lncRNAs in the progression of gallbladder cancer using bioinformatics analyses

Lei Zhang, Zhimin Geng, Xiankui Meng, Fandi Meng, Lin Wang
Pages: 6449-6455
Published online on: 01 March 2018

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Article Open Access

Identification of key genes and long non‑coding RNAs in celecoxib‑treated lung squamous cell carcinoma cell line by RNA‑sequencing

Gang Li, Xuehai Wang, Qingsong Luo, Chongzhi Gan
Pages: 6456-6464
Published online on: 01 March 2018

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Article Open Access

Age-dependent changes in vesicular glutamate transporter 1 and 2 expression in the gerbil hippocampus

Hyo Young Jung, Dae Young Yoo, Joon Ha Park, Jong Whi Kim, Jin Young Chung, Dae Won Kim, Moo‑Ho Won, Yeo Sung Yoon, In Koo Hwang
Pages: 6465-6471
Published online on: 08 March 2018

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Article Open Access

The mRNA, miRNA and lncRNA networks in hepatocellular carcinoma: An integrative transcriptomic analysis from Gene Expression Omnibus

Jian‑Hua Xu, Wei‑Hua Chang, Hang‑Wei Fu, Tao Yuan, Ping Chen
Pages: 6472-6482
Published online on: 07 March 2018

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Article Open Access

High expression of active ATF6 aggravates endoplasmic reticulum stress‑induced vascular endothelial cell apoptosis through the mitochondrial apoptotic pathway

Jingyong Huang, Li Wan, Heping Lu, Xiaoqiang Li
Pages: 6483-6489
Published online on: 01 March 2018

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Article Open Access

Therapeutic window for YC‑1 following glutamate‑induced neuronal damage and transient focal cerebral ischemia

Shih‑Huang Tai, Wei‑Ting Lee, Ai‑Chiang Lee, Yu‑Wen Lin, Hsin‑Yi Hung, Sheng‑Yang Huang, Tian‑Shung Wu, E‑Jian Lee
Pages: 6490-6496
Published online on: 01 March 2018

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Article Open Access

Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery Retraction in /10.3892/mmr.2025.13579 Retraction in /10.3892/mmr.2025.13579

Zhibing Pi, Hai Lin, Jianping Yang
Pages: 6497-6505
Published online on: 27 February 2018

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Article Open Access

Development of podophyllotoxin‑loaded nanostructured lipid carriers for the treatment of condyloma acuminatum

Yan Gao, Kai Han, Qi Wang, Zhili Hu, Qingxiu Liu, Lishi Liu, Kang Zeng
Pages: 6506-6514
Published online on: 07 March 2018

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Article Open Access

Secretome analysis of rat osteoblasts during icariin treatment induced osteogenesis

Weiqing Qian, Yan Su, Yajie Zhang, Nianwei Yao, Nin Gu, Xu Zhang, Hong Yin
Pages: 6515-6525
Published online on: 09 March 2018

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Article Open Access

miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Pages: 6526-6532
Published online on: 01 March 2018

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Article Open Access

Detection of epitopes in systemic lupus erythematosus using peptide microarray

Xin Li, Haixia Li, Qiongdan Hu, Jinfei Lin, Qiong Zhang, Yao Li, Juan Li, Tao Chen, Yurong Qiu
Pages: 6533-6541
Published online on: 09 March 2018

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Article Open Access

Susceptibilities of epicardial and subcutaneous fat tissue for browning-gene expression and diet-induced volume reduction are different

Hiroshi Mikamo, Meizi Jiang, Mahito Noro, Yasuo Suzuki, Nobuyuki Hiruta, Hiroyuki Unoki-Kubota, Wolfgang J. Schneider, Hideaki Bujo
Pages: 6542-6550
Published online on: 06 March 2018

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Article Open Access

Comparative characterization of SHED and DPSCs during extended cultivation in vitro

Huihui Wang, Qi Zhong, Tianshu Yang, Ying Qi, Mengchen Fu, Xi Yang, Lu Qiao, Qi Ling, Shangfeng Liu, Yumei Zhao
Pages: 6551-6559
Published online on: 09 March 2018

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Article Open Access

Sodium selenite induces apoptosis and inhibits autophagy in human synovial sarcoma cell line SW982 in vitro

Le Yang, Yong‑Song Cai, Ke Xu, Jia‑Lin Zhu, Yuan‑Bo Li, Xiao‑Qing Wu, Jian Sun, She‑Min Lu, Peng Xu
Pages: 6560-6568
Published online on: 06 March 2018

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Article Open Access

MicroRNA‑4284 promotes gastric cancer tumorigenicity by targeting ten-eleven translocation 1

Yansen Li, Zhanlong Shen, Hongpeng Jiang, Zhiyong Lai, Zhu Wang, Kewei Jiang, Yingjiang Ye, Shan Wang
Pages: 6569-6575
Published online on: 01 March 2018

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Article Open Access

Macrophage migration inhibitory factor antagonist (S,R)3‑(4‑hydroxyphenyl)‑4,5‑dihydro‑5‑isoxazole acetic acid methyl ester attenuates inflammation and lung injury in rats with acute pancreatitis in pregnancy

Yu Zhou, Liang Zhao, Fangchao Mei, Yupu Hong, He Xia, Teng Zuo, Youming Ding, Weixing Wang
Pages: 6576-6584
Published online on: 01 March 2018

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Article Open Access

Sterol uptake and sterol biosynthesis act coordinately to mediate antifungal resistance in Candida glabrata under azole and hypoxic stress

Qingdi Quentin Li, Huei‑Fung Tsai, Ajeet Mandal, Bryan A. Walker, Jason A. Noble, Yuichi Fukuda, John E. Bennett
Pages: 6585-6597
Published online on: 09 March 2018

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Article Open Access

Upregulated plasmacytoma variant translocation 1 promotes cell proliferation, invasion and metastasis in colorectal cancer

Chaoyu Wang, Xin Zhu, Chibin Pu, Xuan Song
Pages: 6598-6604
Published online on: 01 March 2018

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Article Open Access

TNF‑α and RANKL promote osteoclastogenesis by upregulating RANK via the NF‑κB pathway

Gang Luo, Fangfei Li, Xiaoming Li, Zheng‑Guo Wang, Bo Zhang
Pages: 6605-6611
Published online on: 07 March 2018

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Article Open Access

Store operated calcium channels are associated with diabetic cystopathy in streptozotocin‑induced diabetic rats

Sen Yang, Dongwen Wang, Xiaoming Cao, Xuhui Zhang, Xiaobin Yuan, Tiancheng Yang, Yang Mi
Pages: 6612-6620
Published online on: 09 March 2018

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Article

HIF-1-mediated expression of Foxo1 serves an important role in the proliferation and apoptosis of osteoblasts derived from children's iliac cancellous bone

Gang Xu
Pages: 6621-6631
Published online on: 05 March 2018

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Article

Anti-inflammatory effect of bee venom in an allergic chronic rhinosinusitis mouse model

Seung‑Heon Shin, Mi‑Kyung Ye, Sung‑Yong Choi, Kwan‑Kyu Park
Pages: 6632-6638
Published online on: 09 March 2018

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Article

Artesunate suppresses oxidative and inflammatory processes by activating Nrf2 and ROS‑dependent p38 MAPK and protects against cerebral ischemia‑reperfusion injury

Hui Lu, Bincheng Wang, Ningning Cui, Yanchun Zhang
Pages: 6639-6646
Published online on: 01 March 2018

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Article

Neuroprotective effects of N-acetyl cysteine on primary hippocampus neurons against hydrogen peroxide-induced injury are mediated via inhibition of mitogen-activated protein kinases signal transduction and antioxidative action

Wei Wu, Bao‑Hua Liu, Cheng‑Long Xie, Xiao‑Dong Xia, Yan‑Mei Zhang
Pages: 6647-6654
Published online on: 07 March 2018

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Article

Effect of tumor necrosis factor-α-induced protein 8 on the immune response of CD4+ T lymphocytes in mice following acute insult

Bo Yu, Liang Xu, Ming Cai, Dawei Zhang, Shuxin Li
Pages: 6655-6660
Published online on: 27 February 2018

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Article

Tumor necrosis factor-α downregulates the REIC/Dkk-3 tumor suppressor gene in normal human skin keratinocytes

Ken Kataoka, Natsumi Maehara, Yuki Ayabe, Hitoshi Murata, Nam‑Ho Huh, Masakiyo Sakaguchi
Pages: 6661-6666
Published online on: 05 March 2018

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Article

Grim-19 expressed by recombinant adenovirus for esophageal neoplasm target therapy

Jianxiang Song, Woda Shi, Wencai Wang, Yajun Zhang, Shiying Zheng
Pages: 6667-6674
Published online on: 27 February 2018

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Article

Isoquercetin ameliorates myocardial infarction through anti-inflammation and anti-apoptosis factor and regulating TLR4-NF-κB signal pathway

Chengtai Ma, Yanxia Jiang, Xiaohui Zhang, Xiaoxue Chen, Zhenfang Liu, Xintao Tian
Pages: 6675-6680
Published online on: 09 March 2018

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Article

Upregulation of SIRT1 inhibits H2O2‑induced osteoblast apoptosis via FoxO1/β‑catenin pathway

Hanlin Yao, Zhen Yao, Shaocheng Zhang, Wenjun Zhang, Wen Zhou
Pages: 6681-6690
Published online on: 01 March 2018

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Article

Occurrence of substance P and neurokinin receptors during the early phase of spinal fusion

Suiyi Wu, Ximing Xu, Yao Zhang, Peng Liu, Kaiqiang Sun, Tianming Xu, Jiangang Shi
Pages: 6691-6696
Published online on: 07 March 2018

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Article

Protective effect of α-mangostin against CoCl2-induced apoptosis by suppressing oxidative stress in H9C2 rat cardiomyoblasts

Zhao Fang, Wanjun Luo, Yanli Luo
Pages: 6697-6704
Published online on: 06 March 2018

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Article

MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Pages: 6705-6710
Published online on: 05 March 2018

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Article

Knockdown of ZEB1 suppressed the formation of vasculogenic mimicry and epithelial-mesenchymal transition in the human breast cancer cell line MDA-MB-231

Weili Liang, Shasha Song, Yintao Xu, Huiying Li, Huantao Liu
Pages: 6711-6716
Published online on: 05 March 2018

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Article

Comparison of the common bacteria in human and mouse tumours using high-throughput sequencing

Fenghao Zhang, Mingzheng Zhang, Yuqing Wang, Chengjie Li, Tingtao Chen
Pages: 6717-6722
Published online on: 06 March 2018

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Article

Benzoxazole derivatives suppress lipopolysaccharide-induced mast cell activation

Kyung‑Ah Cho, Minhwa Park, Yu‑Hee Kim, Hea‑Young Park Choo, Kyung Ho Lee
Pages: 6723-6730
Published online on: 09 March 2018

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Article

Expression of Toll‑like receptor 4 on mast cells in gingival tissues of human chronic periodontitis

Bo Huang, Qian Dai, Shi‑Guang Huang
Pages: 6731-6735
Published online on: 27 February 2018

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Article

MicroRNA-124 suppresses growth and aggressiveness of osteosarcoma and inhibits TGF-β-mediated AKT/GSK-3β/SNAIL-1 signaling

Bo Yu, Kaibiao Jiang, Jidong Zhang
Pages: 6736-6744
Published online on: 27 February 2018

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Article

Effects of HAD-B1 on the proliferation of A549 cisplatin-resistant lung cancer cells

Hwa Jeong Kang, Ji‑Hye Park, Hwa‑Seung Yoo, Yu Mi Park, Chong‑Kwan Cho, In‑Cheol Kang
Pages: 6745-6751
Published online on: 07 March 2018

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Article

Dioscin prevents LPS‑induced acute lung injury through inhibiting the TLR4/MyD88 signaling pathway via upregulation of HSP70

Huiqing Zeng, Lijuan Yang, Xiaobin Zhang, Yan Chen, Jianghang Cai
Pages: 6752-6758
Published online on: 01 March 2018

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Article

Association of the PPARγ/PI3K/Akt pathway with the cardioprotective effects of tacrolimus in myocardial ischemic/reperfusion injury

Xiufen Li, Aishan Bilali, Rui Qiao, Tuerxun Paerhati, Yan Yang
Pages: 6759-6767
Published online on: 27 February 2018

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Article

Autophagy inhibition enhanced 5‑FU‑induced cell death in human gastric carcinoma BGC‑823 cells

Xing‑Xing He, Chen‑Kai Huang, Bu‑Shan Xie
Pages: 6768-6776
Published online on: 01 March 2018

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Article

Allicin attenuates lipopolysaccharide‑induced acute lung injury in neonatal rats via the PI3K/Akt pathway

Xudong Wang, Chao Zhang, Chao Chen, Yi Guo, Xiaoyan Meng, Chen Kan
Pages: 6777-6783
Published online on: 07 March 2018

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Article

COMMD7 activates CXCL10 production by regulating NF-κB and the production of reactive oxygen species

Nan You, Jing Li, Xiaobing Huang, Ke Wu, Yichen Tang, Liang Wang, Hongyan Li, Na Mi, Lu Zheng
Pages: 6784-6788
Published online on: 08 March 2018

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Article

High sucrose/fat diet and isosorbide mononitrate increase insulin resistance, nitric oxide production and myocardial apoptosis in a hypertensive rat model

Ting Li, Bing Bai, Chenguang Tian, Huihui Wang, Deyue Jiang, Fangfei Ma, Mengting Shan
Pages: 6789-6795
Published online on: 28 February 2018

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Article

ATRA improves endothelial dysfunction in atherosclerotic rabbits by decreasing CAV‑1 expression and enhancing eNOS activity

Yan Wu, Xiaobian Wang, Qing Zhou, Yi Wang, Jiali Zhou, Qiaoling Jiang, Yuan Wang, Huaqing Zhu
Pages: 6796-6802
Published online on: 27 February 2018

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Article

SOX6 is downregulated in osteosarcoma and suppresses the migration, invasion and epithelial-mesenchymal transition via TWIST1 regulation

Zheng Wang, Junjie Li, Kun Li, Jianjun Xu
Pages: 6803-6811
Published online on: 06 March 2018

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Article

Downregulated CDK10 expression in gastric cancer: Association with tumor progression and poor prognosis

Yanjie You, Feihu Bai, Zhengcai Ye, Nan Zhang, Li Yao, Yuanyuan Tang, Ximei Li
Pages: 6812-6818
Published online on: 01 March 2018

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Article

Oxidative damage and mitochondrial injuries differ following pneumoperitoneum pressure in rabbit models of varying degrees of hydronephrosis

Wei Li, Sheng Zhao, Fan Cheng, Ting Rao, Weimin Yu, Yuan Ruan, Run Yuan, Xiaobing Yao
Pages: 6819-6827
Published online on: 01 March 2018

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Article

Tegillarca granosa extract Haishengsu inhibits tumor activity via a mitochondrial‑mediated apoptotic pathway

Xue‑Hong Chen, Yan‑Tao Han, Jun‑Li Ye, Zhi‑Shang Chang, Chun‑Bo Wang, Shou‑Guo Chen
Pages: 6828-6834
Published online on: 01 March 2018

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Article

Protective effects of icariin on human vascular endothelial cells induced by oxidized low-density lipoprotein via modulating caspase-3 and Bcl-2

Yanwu Hu, Haitao Li, Kai Liu, Yang Zhang, Liqun Ren, Zhimin Fan
Pages: 6835-6839
Published online on: 09 March 2018

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Article

Alogliptin alleviates hepatic steatosis in a mouse model of nonalcoholic fatty liver disease by promoting CPT1a expression via Thr172 phosphorylation of AMPKα in the liver

Hiroshi Tobita, Shuichi Sato, Tomotaka Yazaki, Tsuyoshi Mishiro, Norihisa Ishimura, Shunnji Ishihara, Yoshikazu Kinoshita
Pages: 6840-6846
Published online on: 01 March 2018

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Article

Ebselen suppresses inflammation induced by Helicobacter pylori lipopolysaccharide via the p38 mitogen-activated protein kinase signaling pathway

Ling Xu, Changguo Gong, Guangming Li, Jue Wei, Ting Wang, Wenying Meng, Min Shi, Yugang Wang
Pages: 6847-6851
Published online on: 27 February 2018

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Article

High fish oil diet promotes liver inflammation and activates the complement system

Huimin Jin, Cheng Yan, Tengfei Xiao, Nannan Yan, Jie Xu, Liping Zhou, Xiaoming Zhou, Qixiang Shao, Sheng Xia
Pages: 6852-6858
Published online on: 06 March 2018

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Article

Inhibition of autophagy promotes cisplatin-induced apoptotic cell death through Atg5 and Beclin 1 in A549 human lung cancer cells

Jianhua Chen, Lemeng Zhang, Hui Zhou, Wei Wang, Yongzhong Luo, Hua Yang, Huihuang Yi
Pages: 6859-6865
Published online on: 06 March 2018

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Article

The expression of microRNA-23a regulates acute myocardial infarction in patients and in vitro through targeting PTEN

Shengli Li, Jie Ren, Qianmei Sun
Pages: 6866-6872
Published online on: 27 February 2018

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Article

Protective effects of tetrahydropalmatine against ketamine-induced learning and memory injury via antioxidative, anti-inflammatory and anti-apoptotic mechanisms in mice

Yonglai Zhang, Rui Sha, Kaiguo Wang, Hao Li, Bo Yan, Naibao Zhou
Pages: 6873-6880
Published online on: 07 March 2018

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Article

Neuroprotective effect of berberine agonist against impairment of learning and memory skills in severe traumatic brain injury via Sirt1/p38 MAPK expression

Jianping Wang, Yamin Zhang
Pages: 6881-6886
Published online on: 05 March 2018

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Article

Role of SGLT1 in high glucose level-induced MMP-2 expression in human cardiac fibroblasts

Liping Meng, Hiroyasu Uzui, Hangyuan Guo, Hiroshi Tada
Pages: 6887-6892
Published online on: 06 March 2018

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Article

MicroRNA-383 suppresses cell proliferation and invasion in colorectal cancer by directly targeting paired box 6 Retraction in /10.3892/mmr.2023.13055

Fei Yan, Zhiquan Tu, Li Duan, Dexing Wang , Feng Lin
Pages: 6893-6901
Published online on: 06 March 2018

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Article

Long non-coding RNA TCF7 predicts the progression and facilitates the growth and metastasis of colorectal cancer

Fu‑Shu Jin, Hong‑Mei Wang, Xiao‑Yan Song
Pages: 6902-6908
Published online on: 09 March 2018

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Article

Investigation of the expressions of MMPs and TIMPs between isogeneic and allogeneic rat aortic transplantation

Si‑Dong Wei, Ding Cao, Xue‑Song Xu, He Bai, Hao Wu, Meng‑Hao Wang
Pages: 6909-6913
Published online on: 06 March 2018

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Article

Induction of Th1 chemokine secretion in dermal fibroblasts by vanadium pentoxide

P. Fallahi, R. Foddis, G. Elia, F. Ragusa, A. Patrizio, G. Guglielmi, G. Frenzilli, S. Benvenga, A. Cristaudo, A. Antonelli, S. M. Ferrari
Pages: 6914-6918
Published online on: 09 March 2018

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Article

Leigh syndrome T8993C mitochondrial DNA mutation: Heteroplasmy and the first clinical presentation in a Vietnamese family

Chamara Arachchighe Lahiru Weerasinghe, Bich‑Hong Thi Bui, Thu Thi Vu, Hong‑Loan Thi Nguyen, Bao‑Khanh Phung, Van‑Minh Nguyen, Van‑Anh Pham, Vu‑Hung Cao, Tuan‑Nghia Phan
Pages: 6919-6925
Published online on: 01 March 2018

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Correction Open Access

[Corrigendum] Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats

Xinwei Liu, Jingdong Zhang, Wenfeng Han, Yu Wang, Yunen Liu, Yubiao Zhang, Dapeng Zhou, Liangbi Xiang
Pages: 6926-6926
Published online on: 21 February 2018

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Retraction Open Access

[Retracted] Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo

Xianqing Zhang, Xingbin Hu, Shijie Mu, Yonghua Zhan, Qunxing An, Zhixin Liu, Xiaofeng Huang
Pages: 6927-6927
Published online on: 08 February 2018

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Review

Role of epithelial chemokines in the pathogenesis of airway inflammation in asthma (Review)

Chi Liu, Xun Zhang, Yang Xiang, Xiangping Qu, Huijun Liu, Caixia Liu, Meiling Tan, Jianxin Jiang, Xiaoqun Qin
Pages: 6935-6941
Published online on: 14 March 2018

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Article Open Access

Novel MSH2 splice-site mutation in a young patient with Lynch syndrome

Raffaella Liccardo, Marina De Rosa, Paola Izzo, Francesca Duraturo
Pages: 6942-6946
Published online on: 15 March 2018

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Article Open Access

Effects of Bushen-Yizhi formula on age-related inflammation and oxidative stress in senescence-accelerated mice

Xue‑Qin Hou, Hou‑Pan Song, Yun‑Bo Chen, Shu‑Yi Cheng, Shu‑Huan Fang, Ji‑Guo Zhang, Qi Wang
Pages: 6947-6960
Published online on: 14 March 2018

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Article Open Access

KCC2-GABAA pathway correlates with the analgesic effect of electro-acupuncture in CCI rats

Si‑Si Li, Wen‑Zhan Tu, Cheng‑Qian Jia, Xia Jiang, Xin‑Ru Qian, Guan‑Hu Yang, Qi‑Miao Hu, Wen‑Ci Chen, Bin Lu, Song‑He Jiang
Pages: 6961-6968
Published online on: 16 March 2018

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Article Open Access

Tanshinone‑IIA attenuates the deleterious effects of oxidative stress in osteoporosis through the NF‑κB signaling pathway Retraction in /10.3892/mmr.2023.13140

Shaowen Zhu, Wanfu Wei, Zhiwei Liu, Yang Yang, Haobo Jia
Pages: 6969-6976
Published online on: 14 March 2018

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Article Open Access

Therapeutic effects of liver soothing pingchuan formula decoction on experimental asthma in BALB/c mice via regulation of nerve growth factor-tyrosine kinase A pathway

Xin‑Guang Zhang, Zheng Xue, Yi‑Tao Zhao, Li Bai, Fei Liu, Li‑Qing Li, Jie Wu, Jing‑Dong Zhou, Jian‑Er Yu
Pages: 6977-6984
Published online on: 14 March 2018

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Article Open Access

Screening of potential biomarkers in uterine leiomyomas disease via gene expression profiling analysis

Xuhui Liu, Yanfei Liu, Jingrong Zhao, Yan Liu
Pages: 6985-6996
Published online on: 15 March 2018

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Article Open Access

Effects and mechanism of amyloid β1-42 on mitochondria in astrocytes

Yunyi Yao, Jin‑Zhong Huang, Yingqi Chen, He‑Juan Hu, Xiying Tang, Xianhong Li
Pages: 6997-7004
Published online on: 16 March 2018

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Article Open Access

miR-25 enhances cell migration and invasion in non-small-cell lung cancer cells via ERK signaling pathway by inhibiting KLF4

Xiaoli Ding, Tianyu Zhong, Lixia Jiang, Junyun Huang, Yu Xia, Rong Hu
Pages: 7005-7016
Published online on: 16 March 2018

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Article Open Access

TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Pages: 7017-7026
Published online on: 20 March 2018

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Article Open Access

Integrated analysis of B‑cell and T‑cell receptors by high‑throughput sequencing reveals conserved repertoires in IgA nephropathy

Minglin Ou, Fengping Zheng, Xinzhou Zhang, Song Liu, Donge Tang, Peng Zhu, Jingjun Qiu, Yong Dai
Pages: 7027-7036
Published online on: 20 March 2018

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Article Open Access

Effect of KNDC1 overexpression on the senescence of human umbilical vein endothelial cells

Jinrui Ji, Zhenxuan Hao, Hengliang Liu, Yang Liu, Jing Liu, Binghui Lin, Chao Ma, Yajun Lin
Pages: 7037-7044
Published online on: 19 March 2018

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Article Open Access

ATM‑JAK‑PD‑L1 signaling pathway inhibition decreases EMT and metastasis of androgen‑independent prostate cancer

Lan Zhang, Li‑Jun Xu, Jin Zhu, Jian Li, Bo‑Xin Xue, Jie Gao, Chuan‑Yang Sun, Ya‑Chen Zang, Yi‑Bin Zhou, Dong‑Rong Yang, Yu‑Xi Shan
Pages: 7045-7054
Published online on: 20 March 2018

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Article Open Access

Comparison of mouse brown and white adipose‑derived stem cell differentiation into pacemaker‑like cells induced by TBX18 transduction

Ai‑Jun Sun, Liang Qiao, Chao Huang, Xi Zhang, Yu‑Quan Li, Xiang‑Qun Yang
Pages: 7055-7064
Published online on: 20 March 2018

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Article Open Access

Role of leptin and the leptin receptor in the pathogenesis of varicocele-induced testicular dysfunction

Jie Zhang, Peng‑Peng Jin, Min Gong, Qing‑Tong Yi, Ru‑Jian Zhu
Pages: 7065-7072
Published online on: 15 March 2018

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Article Open Access

Genetic analysis of sick sinus syndrome in a family harboring compound CACNA1C and TTN mutations

Yao‑Bin Zhu, Jie‑Wei Luo, Fen Jiang, Gui Liu
Pages: 7073-7080
Published online on: 16 March 2018

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Article Open Access

miR-34 modulates apoptotic gene expression in Ingenol mebutate treated keloid fibroblasts

Bruna De Felice, Francesco Manfellotto, Corrado Garbi, Margherita Santoriello, Massimo Nacca
Pages: 7081-7088
Published online on: 15 March 2018

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Article Open Access

Low molecular weight fucoidan attenuates experimental abdominal aortic aneurysm through interfering the leukocyte-endothelial cells interaction

Min Zhou, Yong Ding, Liang Cai, Yonggang Wang, Changpo Lin, Zhenyu Shi
Pages: 7089-7096
Published online on: 16 March 2018

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Article Open Access

miR‑133b‑5p contributes to hypoxic preconditioning‑mediated cardioprotection by inhibiting the activation of caspase‑8 and caspase-3 in cardiomyocytes

Yong‑Lu Pan, Zheng‑Yi Han, Shu‑Fang He, Wan Yang, Jie Cheng, Ye Zhang, Zhi‑Wu Chen
Pages: 7097-7104
Published online on: 20 March 2018

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Article Open Access

miR-185 and miR-29a are similarly expressed in the bronchoalveolar lavage cells in IPF and lung cancer but common targets DNMT1 and COL1A1 show disease specific patterns

Eleni Bibaki, Eliza Tsitoura, Eirini Vasarmidi, George Margaritopoulos, Athina Trachalaki, Chara Koutoulaki, Theodora Georgopoulou, Demetrios A. Spandidos, Nikos Tzanakis, Katerina M. Antoniou
Pages: 7105-7112
Published online on: 19 March 2018

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Article Open Access

Involvement of multidrug resistance protein 4 in the hepatocyte efflux of lamivudine and entecavir

Yu‑Tian Liu, Wei Liu, Gang‑Yan Zhu, Fu‑Liang Wang, Qian Chen
Pages: 7113-7121
Published online on: 19 March 2018

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Article Open Access

Tissue expression of Toll-like receptors 2, 3, 4 and 7 in swine in response to the Shimen strain of classical swine fever virus

Zhi Cao, Minping Zheng, Huifang Lv, Kangkang Guo, Yanming Zhang
Pages: 7122-7130
Published online on: 14 March 2018

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Article Open Access

Phylogeny and polymorphism in the long control regions E6, E7, and L1 of HPV Type 56 in women from southwest China

Yaling Jing, Tao Wang, Zuyi Chen, Xianping Ding, Jianju Xu, Xuemei Mu, Man Cao, Honghan Chen
Pages: 7131-7141
Published online on: 14 March 2018

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Article Open Access

Oral supplementation with ursolic acid ameliorates sepsis-induced acute kidney injury in a mouse model by inhibiting oxidative stress and inflammatory responses

Zhenyu Zhang, Hong Zhang, Rui Chen, Zhong Wang
Pages: 7142-7148
Published online on: 16 March 2018

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Article Open Access

Overexpression of appoptosin promotes mitochondrial damage in MIN6 cells

Tianxi Wang, Wenjing Wei, Hussen Amir Ahmed Mansai, Caoxin Huang, Long Li, Qiuhong Ye, Hongyan Yin, Chen Yang, Xuejun Li, Suhuan Liu, Shuyu Yang
Pages: 7149-7155
Published online on: 16 March 2018

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Article Open Access

Protection of Luteolin-7-O-glucoside against apoptosis induced by hypoxia/reoxygenation through the MAPK pathways in H9c2 cells Retraction in /10.3892/mmr.2025.13591

Shenjie Chen, Bingsheng Yang, Yifei Xu, Yiqing Rong, Yuangang Qiu
Pages: 7156-7162
Published online on: 19 March 2018

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Article Open Access

Everolimus inhibits breast cancer cell growth through PI3K/AKT/mTOR signaling pathway Retraction in /10.3892/mmr.2025.13508

Liyan Du, Xiaomei Li, Linhong Zhen, Weiling Chen, Lingguang Mu, Yang Zhang, Ailin Song
Pages: 7163-7169
Published online on: 16 March 2018

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Article Open Access

PEDF regulates lipid metabolism and reduces apoptosis in hypoxic H9c2 cells by inducing autophagy related 5-mediated autophagy via PEDF-R

Yiqian Zhang, Yufeng Li, Zhiwei Liu, Qixiang Zhao, Hao Zhang, Xiaoyu Wang, Peng Lu, Hongli Yu, Meng Wang, Hongyan Dong, Zhongming Zhang
Pages: 7170-7176
Published online on: 14 March 2018

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Article Open Access

Retinal ganglion cell-conditioned medium and surrounding pressure alters gene expression and differentiation of rat retinal progenitor cells

Min Dai, Qing Zhang, Zhikun Zheng, Jianzhou Wang
Pages: 7177-7183
Published online on: 14 March 2018

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Article Open Access

Pyrroloquinoline quinone induces chondrosarcoma cell apoptosis by increasing intracellular reactive oxygen species

Linchun Wen, Xiyan Lu, Rui Wang, Xiaowei Jin, Liqiang Hu, Chuanwen You
Pages: 7184-7190
Published online on: 14 March 2018

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Article Open Access

Adiponectin protects against lung ischemia-reperfusion injury in rats with type 2 diabetes mellitus

Di Li, Lin‑Lin Song, Juan Wang, Chao Meng, Xiao‑Guang Cui
Pages: 7191-7201
Published online on: 14 March 2018

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Article Open Access

miR-590-3p mediates melatonin-induced cell apoptosis by targeting septin 7 in the human osteoblast cell line hFOB 1.19

Xiaotong Meng, Yue Zhu, Lin Tao, Sichao Zhao, Shui Qiu
Pages: 7202-7208
Published online on: 13 March 2018

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Article Open Access

MicroRNA‑22 inhibits the proliferation and migration, and increases the cisplatin sensitivity, of osteosarcoma cells

Xiang Zhou, Dimple Natino, Xu Zhai, Zhongyang Gao, Xijing He
Pages: 7209-7217
Published online on: 20 March 2018

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Article Open Access

PPARα activation alleviates damage to the cytoskeleton during acute myocardial ischemia/reperfusion in rats

Jie Yuan, Hongdan Mo, Jing Luo, Suhong Zhao, Shuang Liang, Yu Jiang, Maomao Zhang
Pages: 7218-7226
Published online on: 16 March 2018

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Article Open Access

Protective effect of curcumin against ultraviolet A irradiation‑induced photoaging in human dermal fibroblasts

Xiaoming Liu, Ruizhi Zhang, Haixia Shi, Xiaobo Li, Yanhong Li, Ahmad Taha, Chunxing Xu
Pages: 7227-7237
Published online on: 20 March 2018

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Article Open Access

Long non-coding RNAs RP5-821D11.7, APCDD1L-AS1 and RP11-277P12.9 were associated with the prognosis of lung squamous cell carcinoma

Yanzhuo Luo, Zhaobo Xuan, Xiaofeng Zhu, Peng Zhan, Zhou Wang
Pages: 7238-7248
Published online on: 16 March 2018

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Article Open Access

Dickkopf‑3 upregulation mediates the cardioprotective effects of curcumin on chronic heart failure

Quan Cao, Junxia Zhang, Ling Gao, Yijie Zhang, Mingyan Dai, Mingwei Bao
Pages: 7249-7257
Published online on: 20 March 2018

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Article Open Access

Dexmedetomidine attenuates H2O2-induced neonatal rat cardiomyocytes apoptosis through mitochondria- and ER-medicated oxidative stress pathways

Xue‑Ru Liu, Tao Li, Lu Cao, Yi‑Yan Yu, Lin‑Lin Chen, Xue‑Hui Fan, Bin‑Bin Yang, Xiao‑Qiu Tan
Pages: 7258-7264
Published online on: 15 March 2018

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Article

Genistein inhibits invasion and migration of colon cancer cells by recovering WIF1 expression

Jie Zhu, Jun Ren, Liming Tang
Pages: 7265-7273
Published online on: 16 March 2018

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Article

Hyperthermia inhibits the motility of gemcitabine-resistant pancreatic cancer PANC-1 cells through the inhibition of epithelial-mesenchymal transition

Hangbin Jin, Yanyan Zhao, Shirong Zhang, Jianfeng Yang, Xiaofeng Zhang, Shenglin Ma
Pages: 7274-7280
Published online on: 16 March 2018

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Article

Puerarin promotes MIN6 cell survival by reducing cellular reactive oxygen species

Tianxi Wang, Yijie Liu, Caoxin Huang, Hussen Amir Ahmed Mansai, Wenjing Wei, Xiaofang Zhang, Xuejun Li, Suhuan Liu, Shuyu Yang
Pages: 7281-7286
Published online on: 14 March 2018

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Article

Neuroprotective effects of salidroside administration in a mouse model of Alzheimer's disease

Qingyun Li, Jinhua Wang, Yuwang Li, Xiaolin Xu
Pages: 7287-7292
Published online on: 15 March 2018

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Article

Ameliorative effect of nicergoline on cognitive function through the PI3K/AKT signaling pathway in mouse models of Alzheimer's disease

Guoyao Zang, Lizheng Fang, Liying Chen, Chenyao Wang
Pages: 7293-7300
Published online on: 20 March 2018

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Article

IL-10 inhibits retinal pigment epithelium cell proliferation and migration through regulation of VEGF in rhegmatogenous retinal detachment

Quiqing Zhao, Mingli Ji, Xuemei Wang
Pages: 7301-7306
Published online on: 20 March 2018

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Article

Expression of Rv2031c-Rv2626c fusion protein in Mycobacterium smegmatis enhances bacillary survival and modulates innate immunity in macrophages

Hong Jiang, Tai‑Lai Luo, Jian Kang, Zhi‑Kai Xu, Li‑Mei Wang
Pages: 7307-7312
Published online on: 16 March 2018

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Article

Downregulation of lncRNA H19 inhibits the migration and invasion of melanoma cells by inactivating the NF‑κB and PI3K/Akt signaling pathways

Zhichao Liao, Jun Zhao, Yun Yang
Pages: 7313-7318
Published online on: 20 March 2018

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Article

Effect of liposome‑mediated HSP27 transfection on collagen synthesis in alveolar type II epithelial cells

Haijing Deng, Xuemin Gao, Haibing Peng, Jin Wang, Xiaoli Hou, Hong Xu, Fang Yang
Pages: 7319-7324
Published online on: 14 March 2018

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Article

Whole exome sequencing identifies novel candidate mutations in a Chinese family with left ventricular noncompaction

Ye Zhou, Zhiyong Qian, Jing Yang, Meng Zhu, Xiaofeng Hou, Yao Wang, Hongping Wu, Jiangang Zou
Pages: 7325-7330
Published online on: 19 March 2018

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Article

Cytoprotective effects of diosmetin against hydrogen peroxide-induced L02 cell oxidative damage via activation of the Nrf2-ARE signaling pathway

Chunjing Wang, Yaping Liao, Shengnan Wang, Dan Wang, Nana Wu, Qingao Xu, Wanwan Jiang, Menran Qiu, Changqing Liu
Pages: 7331-7338
Published online on: 15 March 2018

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Article

Roles of elevated 20‑HETE in the breakdown of blood brain barrier and the severity of brain edema in experimental traumatic brain injury

Liyan Lu, Mingliang Wang, Fang Yuan, Xiaoer Wei, Wenbin Li
Pages: 7339-7345
Published online on: 20 March 2018

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Article

Clinical study of prenatal ultrasonography combined with T‑box transcription factor 1 as a biomarker for the diagnosis of congenital heart disease

Bingcheng Guo, Jing Xiao, Long Li, Shuanglong Wang, Lijuan Wang, Shuyong Liu
Pages: 7346-7350
Published online on: 14 March 2018

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Article

Gefitinib inhibits malignant melanoma cells through the VEGF/AKT signaling pathway

Xuefeng Wan, Yalin Zhu, Lijuan Zhang, Wei Hou
Pages: 7351-7355
Published online on: 13 March 2018

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Article

Tranilast prevents renal interstitial fibrosis by blocking mast cell infiltration in a rat model of diabetic kidney disease

Dan‑Dan Yin, Jun‑Hui Luo, Zhu‑Ye Zhao, Ying‑Jun Liao, Ying Li
Pages: 7356-7364
Published online on: 19 March 2018

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Article

DNA methylation is related to the occurrence of breast cancer and is not affected by culture conditions

Shibao Wang, Yinghui Huang, Xupeng Mu, Tianyang Qi, Sha Qiao, Zhenxia Lu, Hongjun Li
Pages: 7365-7371
Published online on: 14 March 2018

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Article

Liraglutide improves hepatic insulin resistance via the canonical Wnt signaling pathway

Yu Qin, Min Chen, Yan Yang, Xin‑Rong Zhou, Shi‑Ying Shao, Dao‑Wen Wang, Gang Yuan
Pages: 7372-7380
Published online on: 14 March 2018

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Article

Myricitrin ameliorates ethanol-induced steatosis in mouse AML12 liver cells by activating AMPK, and reducing oxidative stress and expression of inflammatory cytokines

Jing Gao, Si Chen, Zikai Qiu, Liping Fang, Lishan Zhang, Chang Guo, Tong Chen, Longxin Qiu
Pages: 7381-7387
Published online on: 14 March 2018

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Article

Downregulation of lncRNA H19 inhibits migration and invasion of human osteosarcoma through the NF-κB pathway

Jun Zhao, Shi‑Tang Ma
Pages: 7388-7394
Published online on: 14 March 2018

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Article

Esculin ameliorates cognitive impairment in experimental diabetic nephropathy and induces anti-oxidative stress and anti-inflammatory effects via the MAPK pathway

Yu Song, Xiaochun Wang, Shengkai Qin, Siheng Zhou, Jiaolun Li, Yue Gao
Pages: 7395-7402
Published online on: 13 March 2018

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Article

Dauricine inhibits viability and induces cell cycle arrest and apoptosis via inhibiting the PI3K/Akt signaling pathway in renal cell carcinoma cells

Shuwei Zhang, Yu Ren, Jianxin Qiu
Pages: 7403-7408
Published online on: 14 March 2018

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Article

Treatment of experimental autoimmune myasthenia gravis rats with FTY720 and its effect on Th1/Th2 cells

Jiankang Huang, Ting Zhang, Hongmei Wang, Yuwu Zhao
Pages: 7409-7414
Published online on: 16 March 2018

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Article

Differential modulation by vanadium pentoxide of the secretion of CXCL8 and CXCL11 chemokines in thyroid cells

Poupak Fallahi, Rudy Foddis, Giusy Elia, Francesca Ragusa, Armando Patrizio, Giada Frenzilli, Salvatore Benvenga, Alfonso Cristaudo, Alessandro Antonelli, Silvia Martina Ferrari
Pages: 7415-7420
Published online on: 16 March 2018

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Article

Puerarin reduces ischemia/reperfusion-induced myocardial injury in diabetic rats via upregulation of vascular endothelial growth factor A/angiotensin-1 and suppression of apoptosis

Bao‑Qiang Guo, Jing‑Bo Xu, Ming Xiao, Min Ding, Li‑Jun Duan
Pages: 7421-7427
Published online on: 15 March 2018

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Article

Tumor necrosis factor-α-induced protein 8-like-2 is involved in the activation of macrophages by Astragalus polysaccharides in vitro

Jie Zhu, Yuanyuan Zhang, Fanghua Fan, Guoyou Wu, Zhen Xiao, Huanqin Zhou
Pages: 7428-7434
Published online on: 13 March 2018

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Article

miR‑494‑BAG‑1 axis is involved in cinobufacini‑induced cell proliferation and apoptosis in gastric cancer

Zhili Shen, Yan Li, Chengcheng Zhao, Fen Wang, Rongping Zhou, Gang Chen
Pages: 7435-7441
Published online on: 20 March 2018

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Article

Downregulation of human choline kinase α gene expression by miR-876-5p

Sharzehan Mohamad Ayub Khan, Ling Ling Few, Wei Cun See Too
Pages: 7442-7450
Published online on: 16 March 2018

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MicroRNA-599 targets high-mobility group AT-hook 2 to inhibit cell proliferation and invasion in clear cell renal carcinoma Retraction in /10.3892/mmr.2023.13041

Hailing Zhao, Huizhen Zhao, Xiaolin Xia, Xiujuan Liu
Pages: 7451-7459
Published online on: 15 March 2018

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[Corrigendum] MicroRNA-137 has a suppressive role in liver cancer via targeting EZH2

Shichang Cui, Yanlei Sun, Yang Liu, Chengbiao Liu, Jinbao Wang, Guang Hao, Qidong Sun
Pages: 7460-7460
Published online on: 20 March 2018

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January-2026 Volume 33 Issue 1

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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