Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
presentation
Molecular Medicine Reports

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

  • Selected Issue
  • Current Issue
  • Forthcoming Issue
  • Special Issues
    • Open Special Issues
    • About Special Issues
  • Trending Articles
    • Most Read
    • Most Cited (Dimensions)
      • Past Two Years
      • Total
    • Most Cited (Crossref)
      • Past Year
      • Total
    • Social Media
      • Past Month
      • Past Year
      • Total
  • Information
    • Information for Authors
    • Contact
    • Editorial Policies
    • Editorial Board
    • Aims and Scope
    • Abstracting and Indexing
    • Bibliographic Information
  • Archive
Journal Cover
September-2019 Volume 20 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Current advances in the study of diabetic cardiomyopathy: From clinicopathological features to molecular therapeutics (Review)

Lin Sun, Ming Yu, Tong Zhou, Siwen Zhang, Guangyu He, Guixia Wang, Xiaokun Gang
Pages: 2051-2062
Published online on: 04 July 2019

  • View Full Article Download
Article Open Access

Identification of a thymus microRNA‑mRNA regulatory network in Down syndrome

Miao Chai, Liju Su, Xiaolei Hao, Meng Zhang, Lihui Zheng, Jiabing Bi, Xiao Han, Chunbo Gao
Pages: 2063-2072
Published online on: 27 June 2019

  • View Full Article Download
Article Open Access

Identification of differentially expressed genes in hip cartilage with femoral head necrosis, based on genome‑wide expression profiles

Wen Chao Li, De Lei Bai, Yang Xu, Rui Jiang Xu, Wen Bo Hou
Pages: 2073-2082
Published online on: 02 July 2019

  • View Full Article Download
Article Open Access

Impact of chronic immobilization stress on parameters of colonic homeostasis in BALB/c mice

Nancy Machorro‑Rojas, Teresita Sainz‑Espuñes, Marycarmen Godínez‑Victoria, Jorge Ismael Castañeda‑Sánchez, Rafael Campos‑Rodríguez, Judith Pacheco‑Yepez, Maria Elisa Drago‑Serrano
Pages: 2083-2090
Published online on: 27 June 2019

  • View Full Article Download
Article Open Access

Dracorhodin perchlorate induces apoptosis and G2/M cell cycle arrest in human esophageal squamous cell carcinoma through inhibition of the JAK2/STAT3 and AKT/FOXO3a pathways

Zhengyang Lu, Chenyang Lu, Cheng Li, Yan Jiao, Yanqing Li, Guangxin Zhang
Pages: 2091-2100
Published online on: 08 July 2019

  • View Full Article Download
Article Open Access

TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats

Xiang Zhong, Qi Xiao, Zhongzhong Liu, Wei Wang, Chin‑Hui Lai, Wang Yang, Pengpeng Yue, Qifa Ye, Jiansheng Xiao
Pages: 2101-2110
Published online on: 27 June 2019

  • View Full Article Download
Article Open Access

miR‑29 promotes the proliferation of cultured rat neural stem/progenitor cells via the PTEN/AKT signaling pathway

Yunan Gao, Hu Qiao, Zhen Lu, Yuxia Hou
Pages: 2111-2118
Published online on: 01 July 2019

  • View Full Article Download
Article Open Access

Dexmedetomidine protects aged rats from postoperative cognitive dysfunction by alleviating hippocampal inflammation

Nianping Chen, Xiufang Chen, Jianping Xie, Chenglong Wu, Jiang Qian
Pages: 2119-2126
Published online on: 27 June 2019

  • View Full Article Download
Article Open Access

miR‑338‑3p suppresses the malignancy of T‑cell lymphoblastic lymphoma by downregulating HOXA3

Li Wang, Minghua Sui, Xiuli Wang
Pages: 2127-2134
Published online on: 01 July 2019

  • View Full Article Download
Article Open Access

Protective effect of ISO‑1 against advanced glycation end product aggravation of PC12 cell injury induced by Aβ1‑40

Ming Yu, Demei Zang, Yuhao Xu, Jie Meng, Shengnan Qian
Pages: 2135-2142
Published online on: 09 July 2019

  • View Full Article Download
Article Open Access

Pinoresinol promotes MC3T3‑E1 cell proliferation and differentiation via the cyclic AMP/protein kinase A signaling pathway

Xin Jiang, Wenjing Chen, Fuguo Shen, Wenlong Xiao, Hongliang Guo, Hang Su, Jiang Xiu, Wencai Sun
Pages: 2143-2150
Published online on: 03 July 2019

  • View Full Article Download
Article Open Access

Tumor‑suppressive miR‑299‑3p inhibits gastric cancer cell invasion by targeting heparanase

Xiangjun Zhou, Mengmou Hu, Zhenghui Ge
Pages: 2151-2158
Published online on: 27 June 2019

  • View Full Article Download
Article Open Access

Silencing RRM2 inhibits multiple myeloma by targeting the Wnt/β‑catenin signaling pathway

Xia Liu, Jiamin Peng, Yayun Zhou, Bei Xie, Jianchao Wang
Pages: 2159-2166
Published online on: 03 July 2019

  • View Full Article Download
Article Open Access

Downregulation of miR‑98 contributes to hypoxic pulmonary hypertension by targeting ALK1

Qingling Li, Xincan Zhou, Xianghui Zhou
Pages: 2167-2176
Published online on: 09 July 2019

  • View Full Article Download
Article Open Access

Associations between the single nucleotide polymorphisms of APOBEC3A, APOBEC3B and APOBEC3H, and chronic hepatitis B progression and hepatocellular carcinoma in a Chinese population

Xiuting He, Hongqin Xu, Xiaomei Wang, Jing Wu, Junqi Niu, Pujun Gao
Pages: 2177-2188
Published online on: 02 July 2019

  • View Full Article Download
Article Open Access

Differential expression of coxsackievirus and adenovirus receptor in endomyocardial tissue of patients with myocarditis

Gustavo E. García‑Becerril, Aníbal E. Cruz‑Montalvo, Miguel A. De La Cruz, Miguel A. Ares, Luis A. Moreno‑Ruiz, Adda J. García‑Chequer, Carmen Maldonado‑Bernal, Luz M. Gómez‑Jiménez, Cesar A. Flores‑García, Martín H. Garrido‑Garduño, María G. Cárdenas‑Mondragón
Pages: 2189-2198
Published online on: 28 June 2019

  • View Full Article Download
Article Open Access

Bioinformatics analysis of mRNA and miRNA microarray to identify the key miRNA‑gene pairs in small‑cell lung cancer

Yun Mao, Peng Xue, Linlu Li, Pengpeng Xu, Yafang Cai, Xuelei Chu, Pengyuan Jiang, Shijie Zhu
Pages: 2199-2208
Published online on: 28 June 2019

  • View Full Article Download
Article Open Access

Comprehensive analysis of expression profiles of long non‑coding RNAs with associated ceRNA network involved in gastric cancer progression

Wei Gu, Jia‑Hui Ren, Xiong Zheng, Xiao‑Ying Hu, Mei‑Jie Hu
Pages: 2209-2218
Published online on: 09 July 2019

  • View Full Article Download
Article Open Access

Salivary microbial analysis of Chinese patients with immunoglobulin A nephropathy

Shaodong Luan, Shuyuan Zhang, Huanli Zhong, Yingwei Zhang, Xing Wei, Renyong Lin, Chundi Li, Ping Zeng, Xi Wang, Weilong Li, Hanchao Gao
Pages: 2219-2226
Published online on: 09 July 2019

  • View Full Article Download
Article Open Access

E3 ubiquitin ligase siah‑1 nuclear accumulation is critical for homocysteine‑induced impairment of C6 astroglioma cells

Xiangzhu Tian, Li Gong, Aiping Jin, Yu Wang, Xiaoyu Zhou, Yan Tan
Pages: 2227-2235
Published online on: 01 July 2019

  • View Full Article Download
Article Open Access

MicroRNA‑330‑5p inhibits osteosarcoma cell growth and invasion by targeting the proto‑oncogene survivin

Hao Wang, Lei Liu, Shiyuan Fang
Pages: 2236-2244
Published online on: 01 July 2019

  • View Full Article Download
Article Open Access

Identification of key pathways and genes in different types of chronic kidney disease based on WGCNA

Yuhe Guo, Junjie Ma, Lanyan Xiao, Jiali Fang, Guanghui Li, Lei Zhang, Lu Xu, Xingqiang Lai, Guanghui Pan, Zheng Chen
Pages: 2245-2257
Published online on: 28 June 2019

  • View Full Article Download
Article Open Access

Inhibition of MCM2 enhances the sensitivity of ovarian cancer cell to carboplatin

Minjie Deng, Jiajun Sun, Suhong Xie, Hui Zhen, Yanchun Wang, Ailing Zhong, Hongqin Zhang, Renquan Lu, Lin Guo
Pages: 2258-2266
Published online on: 09 July 2019

  • View Full Article Download
Article Open Access

Acupuncture attenuates renal interstitial fibrosis via the TGF‑β/Smad pathway

Zheng Zuo, Peidong Huang, Yunwu Jiang, Yi Zhang, Miansheng Zhu
Pages: 2267-2275
Published online on: 04 July 2019

  • View Full Article Download
Article Open Access

Preliminary evaluation of 18F‑AlF‑NOTA‑MAL‑Cys40‑Exendin‑4 in rodent heart after myocardial ischemia and reperfusion

Xietian Pan, Qing Xu, Jiangwei Chen, Tingting Wang, Mingming Zhang, Haichang Wang, Haokao Gao
Pages: 2276-2284
Published online on: 27 June 2019

  • View Full Article Download
Article Open Access

MicroRNA‑20 induces methylation of hepatitis B virus covalently closed circular DNA in human hepatoma cells

In Young Moon, Jae Hee Choi, Jung Wha Chung, Eun Sun Jang, Sook‑Hyang Jeong, Jin‑Wook Kim
Pages: 2285-2293
Published online on: 27 June 2019

  • View Full Article Download
Article Open Access

ATRA protects skin fibroblasts against UV‑induced oxidative damage through inhibition of E3 ligase Hrd1

Xianye Cheng, Wen Qian, Fang Chen, Yi Jin, Fengdi Wang, Xiaoyi Lu, Sae Rom Lee, Dongming Su, Bin Chen
Pages: 2294-2302
Published online on: 01 July 2019

  • View Full Article Download
Article Open Access

Medial prefrontal cortex exacerbates gastric dysfunction of rats upon restraint water‑immersion stress

Dong‑Qin Zhao, Sheng‑Nan Gong, Ying‑Jie Ma, Jian‑Ping Zhu
Pages: 2303-2315
Published online on: 03 July 2019

  • View Full Article Download
Article Open Access

Identification and interaction analysis of key miRNAs in medullary thyroid carcinoma by bioinformatics analysis

Lijie Zhang, Donghui Lu, Meiqin Liu, Mingjin Zhang, Quan Peng
Pages: 2316-2324
Published online on: 03 July 2019

  • View Full Article Download
Article Open Access

Functional analysis of the congenital heart disease‑associated GATA4 H436Y mutation in vitro

Tao Fang, Yanjie Zhu, Anlan Xu, Yanli Zhang, Qingfa Wu, Guoying Huang, Wei Sheng, Mingwu Chen
Pages: 2325-2331
Published online on: 09 July 2019

  • View Full Article Download
Article Open Access

Treatment for benign thyroid nodules with a combination of natural extracts

Felician Stancioiu, Daniel Mihai, Georgios Z. Papadakis, Aristidis Tsatsakis, Demetrios A. Spandidos, Corin Badiu
Pages: 2332-2338
Published online on: 01 July 2019

  • View Full Article Download
Article

Reactive oxygen species induce epithelial‑mesenchymal transition, glycolytic switch, and mitochondrial repression through the Dlx‑2/Snail signaling pathways in MCF‑7 cells

Su Yeon Lee, Min Kyung Ju, Hyun Min Jeon, Yig Ji Lee, Cho Hee Kim, Hye Gyeong Park, Song Iy Han, Ho Sung Kang
Pages: 2339-2346
Published online on: 03 July 2019

  • View Full Article Download
Article

Bufadienolides induce apoptosis and autophagy by inhibiting the AKT signaling pathway in melanoma A‑375 cells

Huannan Li, Xiaoren Cao, Xiongbing Chen, Xiaohong Yi, Jun Xia, Jilan Chen, Lan Yang
Pages: 2347-2354
Published online on: 01 July 2019

  • View Full Article Download
Article

Construction of chimeric antigen receptor‑modified T cells targeting EpCAM and assessment of their anti‑tumor effect on cancer cells

Yan Zhou, Ping Wen, Mingmei Li, Yaqi Li, Xiao‑An Li
Pages: 2355-2364
Published online on: 03 July 2019

  • View Full Article Download
Article

CPCGI confers neuroprotection by enhancing blood circulation and neurological function in cerebral ischemia/reperfusion rats

Yifeng Miao, Ran Wang, Hui Wu, Shaofeng Yang, Yongming Qiu
Pages: 2365-2372
Published online on: 04 July 2019

  • View Full Article Download
Article Open Access

Identification of a novel mutation site in maturity‑onset diabetes of the young in a Chinese family by whole‑exome sequencing

Han Yu, Jingjin Liu, Xiaofei Li, Fang Miao, Yanlan Yang
Pages: 2373-2380
Published online on: 03 July 2019

  • View Full Article Download
Article

Insulin‑like growth factor 1 inhibits phagocytosis of alveolar epithelial cells in asthmatic mice

Mimi Mu, Fengjiao Wu, Jing He, Xu Tang, Hua Ma, Shujun Guo, Chuanwang Song
Pages: 2381-2388
Published online on: 02 July 2019

  • View Full Article Download
Article

Inhibitory effects of plasmid small interfering RNA targeting signal transducer and activator of transcription‑3 in C6 glioma cells

Jiajun Chen, Yue Zhou, Xiangyu Zhou, Jia Li, Feng Liu, Qingwei Zhou
Pages: 2389-2395
Published online on: 03 July 2019

  • View Full Article Download
Article

UA promotes epithelial‑mesenchymal transition in peritoneal mesothelial cells

Chao‑Yang Duan, Jin Han, Chong‑Yu Zhang, Kunyi Wu, Yan Lin
Pages: 2396-2402
Published online on: 09 July 2019

  • View Full Article Download
Article

Construction of engineered myocardial tissues in vitro with cardiomyocyte‑like cells and a polylactic‑co‑glycolic acid polymer

Yujie Xing, Shuang Shi, Yong Zhang, Fuqiang Liu, Ling Zhu, Binya Shi, Junkui Wang
Pages: 2403-2409
Published online on: 27 June 2019

  • View Full Article Download
Article

Bortezomib promotes apoptosis of multiple myeloma cells by regulating HSP27

Jing Li, Xiaomei Zhang, Jiaying Shen, Jun Guo, Xiaolin Wang, Jiaqiang Liu
Pages: 2410-2418
Published online on: 03 July 2019

  • View Full Article Download
Article

Effect of endoplasmic reticulum calcium on paraquat‑induced apoptosis of human lung type II alveolar epithelial A549 cells

Chun‑Qing Song, Da‑Zhuang Sun, Yong‑Min Xu, Chen Yang, Quan Cai, Xue‑Song Dong
Pages: 2419-2425
Published online on: 04 July 2019

  • View Full Article Download
Article

Dynamic changes in the level of WT1 as an MRD marker to predict the therapeutic outcome of patients with AML with and without allogeneic stem cell transplantation

Huasheng Liu, Xiaoning Wang, Hailing Zhang, Jincheng Wang, Ying Chen, Tiantian Ma, Jing Shi, Ya Kang, Jieying Xi, Mengchang Wang, Mei Zhang
Pages: 2426-2432
Published online on: 28 June 2019

  • View Full Article Download
Article

Long non‑coding RNA plasmacytoma variant translocation 1 gene promotes the development of cervical cancer via the NF‑κB pathway

Chang Wang, Hao Zou, Hongjuan Yang, Lei Wang, Huijun Chu, Jinwen Jiao, Yankui Wang, Aiping Chen
Pages: 2433-2440
Published online on: 09 July 2019

  • View Full Article Download
Article

Epithelial‑mesenchymal transition in chronic rhinosinusitis (CRS) and the prognostic value of α‑SMA in postoperative outcomes of patients with CRS

Han Li, Quan Liu, Huan Wang, Xi‑Cai Sun, Hua‑Peng Yu, Li Hu, De‑Hui Wang
Pages: 2441-2449
Published online on: 03 July 2019

  • View Full Article Download
Article

Ascorbic acid attenuates cell stress by activating the fibroblast growth factor 21/fibroblast growth factor receptor 2/adiponectin pathway in HepG2 cells

Xinqian Gu, Xiao Luo, Yanxin Wang, Zhangya He, Xiaomin Li, Kunjin Wu, Yifan Zhang, Yafeng Yang, Jing Ji, Xiaoqin Luo
Pages: 2450-2458
Published online on: 02 July 2019

  • View Full Article Download
Article

Significance of the microRNA‑17‑92 gene cluster expressed in B‑cell non‑Hodgkin's lymphoma

Shujie Yan, Chuiming Jia, Lina Quan, Lina Zhao, Yuyang Tian, Aichun Liu
Pages: 2459-2467
Published online on: 01 July 2019

  • View Full Article Download
Article

miR‑28‑5p suppresses cell proliferation and weakens the progression of polycystic ovary syndrome by targeting prokineticin‑1

Lyuhe Meng, Haiyan Yang, Congcong Jin, Song Quan
Pages: 2468-2475
Published online on: 01 July 2019

  • View Full Article Download
Article

Effect of S100A8 and S100A9 on expressions of cytokine and skin barrier protein in human keratinocytes

Mun Jeong Kim, Mi Ae Im, Ji‑Sook Lee, Ji Young Mun, Da Hye Kim, Ayoung Gu, In Sik Kim
Pages: 2476-2483
Published online on: 01 July 2019

  • View Full Article Download
Article

MicroRNA‑140 suppresses Helicobacter pylori‑positive gastric cancer growth by enhancing the antitumor immune response

Min Zhao, Qian Liu, Wenxiang Liu, He Zhou, Xuan Zang, Jiangyang Lu
Pages: 2484-2492
Published online on: 08 July 2019

  • View Full Article Download
Article

Upregulation of EPS8L3 is associated with tumorigenesis and poor prognosis in patients with liver cancer

Peng Li, Ting Hu, Hongsheng Wang, Ying Tang, Yue Ma, Xiaodong Wang, Yansong Xu, Guangyu Chen
Pages: 2493-2499
Published online on: 04 July 2019

  • View Full Article Download
Retraction Open Access

[Retracted] miR‑127 aggravates myocardial failure by promoting the TGF‑β1/Smad3 signaling

Hainian Xu, Fengmei Li
Pages: 2500-2500
Published online on: 28 June 2019

  • View Full Article Download
Article Open Access

Alleviation of sepsis‑induced cardiac dysfunction by overexpression of Sestrin2 is associated with inhibition of p‑S6K and activation of the p‑AMPK pathway

Ziwen Wang, Lin Bu, Peng Yang, Shoujie Feng, Feng Xu
Pages: 2511-2518
Published online on: 23 July 2019

  • View Full Article Download
Article Open Access

DNA hypermethylation of aurora kinase A in hepatitis C virus‑positive hepatocellular carcinoma

Zuohong Ma, Yefu Liu, Zhiqiang Hao, Xiangdong Hua, Wenxin Li
Pages: 2519-2532
Published online on: 11 July 2019

  • View Full Article Download
Article Open Access

MicroRNA‑539 inhibits the proliferation and migration of gastric cancer cells by targeting SRY‑box 5 gene

Shi Ding, Yanping Zhang
Pages: 2533-2540
Published online on: 11 July 2019

  • View Full Article Download
Article Open Access

LncRNA SNHG6 inhibits cell proliferation and metastasis by targeting ETS1 via the PI3K/AKT/mTOR pathway in colorectal cancer

Su Meng, Zhao Jian, Xiaofei Yan, Jibin Li, Rui Zhang
Pages: 2541-2548
Published online on: 19 July 2019

  • View Full Article Download
Article Open Access

Abnormal expression of circRNA_089763 in the plasma exosomes of patients with post‑operative cognitive dysfunction after coronary artery bypass grafting

Maozhou Wang, Pixiong Su, Yan Liu, Xitao Zhang, Jun Yan, Xiangguang An, Xiaobin Wang, Song Gu
Pages: 2549-2562
Published online on: 24 July 2019

  • View Full Article Download
Article Open Access

MicroRNA‑34a‑3p inhibits proliferation of rheumatoid arthritis fibroblast‑like synoviocytes

Chunfeng Hou, Dan Wang, Lihua Zhang
Pages: 2563-2570
Published online on: 23 July 2019

  • View Full Article Download
Article Open Access

Two novel 1,4‑naphthoquinone derivatives induce human gastric cancer cell apoptosis and cell cycle arrest by regulating reactive oxygen species‑mediated MAPK/Akt/STAT3 signaling pathways

Hao Wang, Ying‑Hua Luo, Gui‑Nan Shen, Xian‑Ji Piao, Wan‑Ting Xu, Yi Zhang, Jia‑Ru Wang, Yu‑Chao Feng, Jin‑Qian Li, Yu Zhang, Tong Zhang, Shi‑Nong Wang, Hui Xue, Hong‑Xing Wang, Chang‑Yuan Wang, Cheng‑Hao Jin
Pages: 2571-2582
Published online on: 15 July 2019

  • View Full Article Download
Article Open Access

Expression and significance of Annexin A3 in the osteosarcoma cell lines HOS and U2OS

Xinxin Zeng, Shengtao Wang, Peng Gui, Hao Wu, Zhaoxu Li
Pages: 2583-2590
Published online on: 23 July 2019

  • View Full Article Download
Article Open Access

Long non‑coding RNA SLNCR1 regulates non‑small cell lung cancer migration, invasion and stemness through interactions with secretory phospholipase A2

Wen Xu, Quan Xu, Dinghua Kuang, Zhongjun Wang, Qiuliang Lu, Qing Lin, Hao Wu, Liru Chen
Pages: 2591-2596
Published online on: 23 July 2019

  • View Full Article Download
Article Open Access

Identification of core genes and pathways in type 2 diabetes mellitus by bioinformatics analysis

Linchao Ding, Lei Fan, Xiaodong Xu, Jianfei Fu, Yadong Xue
Pages: 2597-2608
Published online on: 24 July 2019

  • View Full Article Download
Article Open Access

Identification of novel cadherin 23 variants in a Chinese family with hearing loss

Tianni Xu, Wei Zhu, Ping Wang, Haonan Li, Shuyuan Yu
Pages: 2609-2616
Published online on: 15 July 2019

  • View Full Article Download
Article Open Access

Integrative analysis of the contribution of mRNAs and long non‑coding RNAs to the pathogenesis of asthma

Xiaochuang Liu, Yanyan Zhang, Hui Jiang, Nannan Jiang, Jiarong Gao
Pages: 2617-2624
Published online on: 19 July 2019

  • View Full Article Download
Article Open Access

miR‑195 suppresses metastasis and angiogenesis of squamous cell lung cancer by inhibiting the expression of VEGF

Hailin Liu, Yulong Chen, Yue Li, Chenguang Li, Tingting Qin, Ming Bai, Zhenfa Zhang, Rui Jia, Yanjun Su, Changli Wang
Pages: 2625-2632
Published online on: 12 July 2019

  • View Full Article Download
Article Open Access

MicroRNA‑let‑7a inhibition inhibits LPS‑induced inflammatory injury of chondrocytes by targeting IL6R

Cong Sui, Lecheng Zhang, Yong Hu
Pages: 2633-2640
Published online on: 12 July 2019

  • View Full Article Download
Article Open Access

1,25‑Dihydroxyvitamin D3 enhances the susceptibility of anaplastic thyroid cancer cells to adriamycin‑induced apoptosis by increasing the generation of reactive oxygen species

Ting Zhang, Liang He, Wei Sun, Yuan Qin, Ping Zhang, Hao Zhang
Pages: 2641-2648
Published online on: 25 July 2019

  • View Full Article Download
Article Open Access

Knockdown of microRNA‑143‑5p by STTM technology affects eumelanin and pheomelanin production in melanocytes

Shuhui Qi, Bo Liu, Junzhen Zhang, Xuexian Liu, Changsheng Dong , Ruiwen Fan
Pages: 2649-2656
Published online on: 12 July 2019

  • View Full Article Download
Article Open Access

Identification of a key candidate gene‑phenotype network mediated by glycyrrhizic acid using pharmacogenomic analysis

Shiqun Wang, Lu Li, Long Shi
Pages: 2657-2666
Published online on: 12 July 2019

  • View Full Article Download
Article Open Access

Role of TGF‑β in the motility of ShcD‑overexpressing 293 cells

Sara Amer, Fadi Alsayegh, Zeina Mashaal, Salma Mohamed, Nour Shawa, Keerthi Rajan, Samrein B.M. Ahmed
Pages: 2667-2674
Published online on: 23 July 2019

  • View Full Article Download
Article Open Access

Ultrasound improves the outcomes of cardiopulmonary resuscitation in rats by stimulating the cholinergic anti‑inflammatory pathway

Yuhan Zhang, Yue Song, Tingting Shu, Licai Liang, Weijing Shao, Lang Guo, Peng Sun
Pages: 2675-2684
Published online on: 25 July 2019

  • View Full Article Download
Article Open Access

Long non‑coding RNA MEG‑3 suppresses gastric carcinoma cell growth, invasion and migration via EMT regulation

Junquan Jiao, Shaobo Zhang
Pages: 2685-2693
Published online on: 23 July 2019

  • View Full Article Download
Article Open Access

Complement factor H‑related 3 overexpression affects hepatocellular carcinoma proliferation and apoptosis

Hong Liu, Ligang Zhang, Pengyan Wang
Pages: 2694-2702
Published online on: 23 July 2019

  • View Full Article Download
Article Open Access

Elevated microRNA‑145‑5p increases matrix metalloproteinase‑9 by activating the nuclear factor‑κB pathway in rheumatoid arthritis

Xiaoxue Wang, Ke Tang, Yuanyuan Wang, Yaqing Chen, Mengchen Yang, Chungang Gu, Jing Wang, Yi Wang, Yuhua Yuan
Pages: 2703-2711
Published online on: 15 July 2019

  • View Full Article Download
Article Open Access

Identification of driver genes and key pathways of prolactinoma predicts the therapeutic effect of genipin

Sheng Zhong, Bo Wu, Xinhui Wang, Dandan Sun, Daqun Liu, Shanshan Jiang, Junliang Ge, Yuan Zhang, Xinrui Liu, Xiaoli Zhou, Rihua Jin, Yong Chen
Pages: 2712-2724
Published online on: 18 July 2019

  • View Full Article Download
Article Open Access

MPZL1 is highly expressed in advanced gallbladder carcinoma and promotes the aggressive behavior of human gallbladder carcinoma GBC‑SD cells

Xiaolei Liu, Jia Huang, Liguo Liu, Rong Liu
Pages: 2725-2733
Published online on: 18 July 2019

  • View Full Article Download
Article Open Access

Quantitative profiling of regional protein expression in rat retina after partial optic nerve transection using fluorescence difference two‑dimensional gel electrophoresis

Chuen Lam, King Kit Li, Chi Wai Do, Henry Chan, Chi Ho To, Jacky Man Kwong Kwong
Pages: 2734-2742
Published online on: 25 July 2019

  • View Full Article Download
Article Open Access

Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice

Qi Li, Beibei Liu, Katja Breitkopf‑Heinlein, Honglei Weng, Qianqian Jiang, Peiling Dong, Steven Dooley, Keshu Xu, Huiguo Ding
Pages: 2743-2753
Published online on: 19 July 2019

  • View Full Article Download
Article Open Access

Overexpression of the hyperplasia suppressor gene inactivates airway fibroblasts obtained from a rat model of chronic obstructive pulmonary disease by inhibiting the Wnt signaling pathway

Zhenghang Ge, Yi Yang, Xun Zhou, Jun Zhang, Bo Li, Xinxing Wang, Xian Luo
Pages: 2754-2762
Published online on: 15 July 2019

  • View Full Article Download
Article Open Access

Overexpression of TG2 enhances the differentiation of ectomesenchymal stem cells into neuron‑like cells and promotes functional recovery in adult rats following spinal cord injury

Wentao Shi, Yunduan Que, Demin Lv, Shiqi Bi, Zhonghua Xu, Dongmin Wang, Zhijian Zhang
Pages: 2763-2773
Published online on: 15 July 2019

  • View Full Article Download
Article Open Access

miR‑185 regulates the growth of osteosarcoma cells via targeting Hexokinase 2

Chaojian Liu, Lajia Cai, Haomiao Li
Pages: 2774-2782
Published online on: 25 July 2019

  • View Full Article Download
Article Open Access

Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial‑ mesenchymal transition via the AKT/GSK‑3β/Snail signaling pathway Corrigendum in /10.3892/mmr.2022.12870

Li Yuan, Mengmeng Zhou, Dawei Huang, Harpreet S. Wasan, Kai Zhang, Leitao Sun, Hong Huang, Shenglin Ma, Minhe Shen, Shanming Ruan
Pages: 2783-2795
Published online on: 25 July 2019

  • View Full Article Download
Article Open Access

Downregulated microRNA‑133a induces HUVECs injury: Potential role of the (pro) renin receptor in angiotensin II‑dependent hypertension

Bing Liu, Ming Lan, Huali Wei, Dapeng Zhang, Junmeng Liu, Jiwei Teng
Pages: 2796-2804
Published online on: 23 July 2019

  • View Full Article Download
Article Open Access

Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ

Lu‑Na Ge, Lei Yan, Cheng Li, Kai Cheng
Pages: 2805-2811
Published online on: 11 July 2019

  • View Full Article Download
Article Open Access

The role of Zeb1 in the pathogenesis of morbidly adherent placenta Retraction in /10.3892/mmr.2025.13493

Na Li, Tian Yang, Wenqian Yu, Hao Liu, Chong Qiao, Caixia Liu
Pages: 2812-2822
Published online on: 12 July 2019

  • View Full Article Download
Article Open Access

Development of c‑MET‑specific chimeric antigen receptor‑engineered natural killer cells with cytotoxic effects on human liver cancer HepG2 cells

Bing Liu, Zheng‑Zhi Liu, Mei‑Ling Zhou, Jian‑Wei Lin, Xue‑Mei Chen, Zhu Li, Wen‑Bin Gao, Zhen‑Dong Yu, Tao Liu
Pages: 2823-2831
Published online on: 25 July 2019

  • View Full Article Download
Article Open Access

High glucose and bupivacaine‑induced cytotoxicity is mediated by enhanced apoptosis and impaired autophagy via the PERK‑ATF4‑CHOP and IRE1‑TRAF2 signaling pathways

Yongzhe Liu, Li Sun, Yaqun Ma, Biyu Wei, Minglong Gao, Lixin Shang
Pages: 2832-2842
Published online on: 25 July 2019

  • View Full Article Download
Article

MicroRNA‑671‑3p regulates the development of knee osteoarthritis by targeting TRAF3 in chondrocytes

Zhengjie Liu, Shunguang Chen, Yezi Yang, Shengjun Lu, Xunming Zhao, Biao Hu, Hong Pei
Pages: 2843-2850
Published online on: 11 July 2019

  • View Full Article Download
Article

circRNA_0006393 promotes osteogenesis in glucocorticoid‑induced osteoporosis by sponging miR‑145‑5p and upregulating FOXO1

Xing‑Bo Wang, Peng‑Biao Li, Shi‑Fang Guo, Qing‑Shan Yang, Zhi‑Xin Chen, Dachuan Wang, Song‑Bo Shi
Pages: 2851-2858
Published online on: 12 July 2019

  • View Full Article Download
Article

Mitofusin2 regulates the proliferation and function of fibroblasts: The possible mechanisms underlying pelvic organ prolapse development

Xiaoqing Wang, Xiaoxiao Wang, Yingfang Zhou, Chao Peng, Huayun Chen, Ye Lu
Pages: 2859-2866
Published online on: 15 July 2019

  • View Full Article Download
Article

The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway

Xiaolong Zhang, Hongmin Bu, Yan Jiang, Guangda Sun, Ruizhi Jiang, Xiaoyan Huang, Huifang Duan, Zhiheng Huang, Qinan Wu
Pages: 2867-2874
Published online on: 12 July 2019

  • View Full Article Download
Article

Linc‑pint overexpression inhibits the growth of gastric tumors by downregulating HIF‑1α

Lei Hong, Junyan Wang, Haijuan Wang, Suju Wei, Fan Zhang, Jing Han, Yan Liu, Minting Ma, Chengyuan Liu, Yu Xu, Wei Liu
Pages: 2875-2881
Published online on: 25 July 2019

  • View Full Article Download
Article

Identification of clinically relevant subgroups of COPD based on airway and circulating autoantibody profiles

Zhenyu Liang, Fei Long, Fengyan Wang, Yuqiong Yang, Jing Xiao, Kuimiao Deng, Weili Gu, Luqian Zhou, Jiaxing Xie, Wenhua Jian, Xin Chen, Mei Jiang, Jinping Zheng, Tao Peng, Rongchang Chen
Pages: 2882-2892
Published online on: 12 July 2019

  • View Full Article Download
Article

Formononetin ameliorates high glucose‑induced endothelial dysfunction by inhibiting the JAK/STAT signaling pathway

Zhen Zhou, Xinjian Zhou, Youhong Dong, Mingyi Li, Yancheng Xu
Pages: 2893-2901
Published online on: 19 July 2019

  • View Full Article Download
Article

Evaluation of serum biomarkers and efficacy of MTX in women with ectopic pregnancy

Haiyan Li, Ying Liu, Shubin Wen, Hanbing Jia, Yuanjie Du
Pages: 2902-2908
Published online on: 25 July 2019

  • View Full Article Download
Article

Improved antitumor efficacy of neutrophils stimulated by bacillus Calmette‑Guérin

Huan Wang, Danan Wang, Yonghui Feng, Jingbo Zhai, Changlong Lu
Pages: 2909-2915
Published online on: 25 July 2019

  • View Full Article Download
Article

Extraction and identification of platelet‑derived microparticles

Jun Guo, Can Feng, Bili Zhang, Shiyang Zhang, Xiaxian Shen, Jiaqi Zhu, Xian‑Xian Zhao
Pages: 2916-2921
Published online on: 09 July 2019

  • View Full Article Download
Article

Identification of CRB1 mutations in two Chinese consanguineous families exhibiting autosomal recessive retinitis pigmentosa

Xiaoxin Guo, Jie Li, Qingwei Wang, Yi Shu, Jin Wang, Lijia Chen, Houbin Zhang, Yi Shi, Jiyun Yang, Fang Lu, Li Jiang, Chao Qu, Bo Gong
Pages: 2922-2928
Published online on: 12 July 2019

  • View Full Article Download
Article

All‑trans‑retinoic acid modulates TGF‑β‑induced apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling

Lingling Liang, Xiaomei Wang, Yajuan Zheng, Yang Liu
Pages: 2929-2935
Published online on: 18 July 2019

  • View Full Article Download
Article

TRIM67 promotes NF‑κB pathway and cell apoptosis in GA‑13315‑treated lung cancer cells

Rui Liu, Yajuan Chen, Tao Shou, Jing Hu, Jingbo Chen, Chen Qing
Pages: 2936-2944
Published online on: 19 July 2019

  • View Full Article Download
Article

N‑acetyl cysteine inhibits lipopolysaccharide‑induced apoptosis of human umbilical vein endothelial cells via the p38MAPK signaling pathway

Ting Xiong, Zhenzhen Zhang, Rui Zheng, Jialin Huang , Ling Guo
Pages: 2945-2953
Published online on: 25 July 2019

  • View Full Article Download
Article

Antidepressant effect of venlafaxine in chronic unpredictable stress: Evidence of the involvement of key enzymes responsible for monoamine neurotransmitter synthesis and metabolism

Dan Liu, Xiao‑Ya Hu, Hai‑Jian Xia, Li‑Jia Wang, Ping Shi, Xiang‑Pan Chen, Qi‑Xin Zhou
Pages: 2954-2962
Published online on: 12 July 2019

  • View Full Article Download
Article

Development of a novel method for visualizing restricted diffusion using subtraction of apparent diffusion coefficient values

Yuuki Yoshimura, Masahiro Kuroda, Irfan Sugianto, Abdullah Khasawneh, Babatunde O. Bamgbose, Kentaro Hamada, Majd Barham, Nouha Tekiki, Akira Kurozumi, Toshi Matsushita, Seiichiro Ohno, Susumu Kanazawa, Junichi Asaumi
Pages: 2963-2969
Published online on: 25 July 2019

  • View Full Article Download
Journal Cover
January-2026 Volume 33 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

  • View Full Article Download
Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

  • View Full Article Download
Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

  • View Full Article Download
Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

  • View Full Article Download
Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

  • View Full Article Download
Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

  • View Full Article Download
Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

  • View Full Article Download
Article Open Access

Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

  • View Full Article Download
Article Open Access

Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

  • View Full Article Download
Review Open Access

Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

  • View Full Article Download
Article Open Access

Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

  • View Full Article Download
Review Open Access

The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

  • View Full Article Download
Article Open Access

Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

  • View Full Article Download
Review Open Access

Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

  • View Full Article Download
Review Open Access

From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

  • View Full Article Download
Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

  • View Full Article Download
Review Open Access

Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

  • View Full Article Download
Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

  • Purchase Full Text Article Purchase Download
Review Open Access

Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

  • View Full Article Download
Article Open Access

Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

  • View Full Article Download
Article Open Access

Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

  • View Full Article Download
Article Open Access

Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

  • View Full Article Download
Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

  • Purchase Full Text Article Purchase Download
Retraction Open Access

[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

  • View Full Article Download
Article Open Access

Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

  • View Full Article Download
Review Open Access

R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

  • View Full Article Download
Review Open Access

Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

  • View Full Article Download
Article Open Access

PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

  • View Full Article Download
Review Open Access

Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

  • View Full Article Download
Article Open Access

MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

  • View Full Article Download
Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

  • View Full Article Download
Journal Cover
February-2026 Volume 33 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

  • Download
Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

  • Download
Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

  • Purchase Download
Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

  • Download
Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

  • Download
Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

  • Download
Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

  • Download
Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

  • Download
Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

  • Download
Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

  • View Full Article Download
Select a topic from the Information tab...
Special issues coming soon...
No data
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team