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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2025 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Oncogenic role of the brain‑derived neurotrophic factor‑TrkB axis with a focus on gallbladder cancer (Review)

Shivani Bansal, Suresh T. Hedau, Shinjinee Sengupta, Puja Sakhuja, Anil Agarwal, Sompal Singh, Ratna Chopra, Sanjay Gupta, Priti Singh, Manoj Andley, Ruchika Gupta
Article Number: 205
Published online on: 19 May 2025

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Indolepropionic acid modulates the immune response in allergic rhinitis through the AKT/CEBPB/IL‑10 signaling pathway

Lu Gao, Yulan Song, Fengyao Zhang, Yan Zhao, Huixuan Hu, Yan Feng
Article Number: 204
Published online on: 19 May 2025

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Identification of metabolites associated with capecitabine‑induced hand‑foot syndrome using untargeted metabolomics in patients with cancer

Yuru Bai, Hong Chen, Leying Gu, Bo Shi, Zhen Wang, Yuanyuan Duanmu, Ying Hu, Yu Wang, Chaoyi Zhang, Zhaotian Su
Article Number: 203
Published online on: 14 May 2025

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Co‑treatment with triptolide and RSL3 induces hepatocellular carcinoma cell apoptosis and ferroptosis

Weixia Liu, Guodi Wu, Jing Wang, Shanshan Wu, Zhi Chen
Article Number: 202
Published online on: 13 May 2025

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Review Open Access

Zinc in psychosis (Review)

Christos Theleritis, Marina Demetriou, Maria-Ioanna Stefanou, Evangelos Alevyzakis, Michael Makris, Vassilios Zoumpourlis, Melpomeni Peppa, Nikolaos Smyrnis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 201
Published online on: 13 May 2025

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Roles of Piezo1 in chronic inflammatory diseases and prospects for drug treatment (Review)

Jun Yang, Chunmei Xu, Xudong Xie, Jun Wang, Peilei Shi
Article Number: 200
Published online on: 12 May 2025

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The role of m6A methylation in abdominal aortic aneurysms: Mechanisms, progress and future perspectives (Review)

Keyu Wang, Ziqiang Sun
Article Number: 199
Published online on: 12 May 2025

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Article Open Access

Novel compound heterozygous mutation in DNAH9 causes complex congenital heart disease

Xiao Liu, Jing‑Lin Zhou, Cheng-Ying Yang, Hai-Yan Zhou, Wen-Bin He, Jing Yang
Article Number: 198
Published online on: 12 May 2025

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Glucose, glutamine, lactic acid and α‑ketoglutarate restore metabolic disturbances and atrophic changes 
in energy‑deprived muscle cells

Miu Ikeda, Moe Matsumoto, Miki Tamura, Masaki Kobayashi, Kaoruko Iida
Article Number: 197
Published online on: 12 May 2025

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Retraction Open Access

[Retracted] Crocin protects against dexamethasone‑induced osteoblast apoptosis by inhibiting the ROS/Ca2+‑mediated mitochondrial pathway

Zhigang Nie, Shuang Deng, Lei Zhang, Sen Chen, Qiang Lu, Hao Peng
Article Number: 196
Published online on: 12 May 2025

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Article

The corticotropin‑releasing factor family in the urogenital system (Review)

Charalampos Mavridis, Eleni Paspalaki, Aristidis Tsatsakis, Charalampos Mamoulakis
Article Number: 195
Published online on: 07 May 2025

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Retraction Open Access

[Retracted] Overexpression of microRNA‑155 alleviates palmitate‑induced vascular endothelial cell injury in human umbilical vein endothelial cells by negatively regulating the Wnt signaling pathway

Yanping Zhao, Wenquan Rao, Yanna Wan, Xinglong Yang, Guorong Wang, Jun Deng, Min Dai, Qiang Liu
Article Number: 194
Published online on: 06 May 2025

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Review

Role of the SWI/SNF complex in the development of digestive tumors (Review)

Shihang Xue, Haiting Yu, Liuhai Zeng, Minzhi Chen
Article Number: 193
Published online on: 05 May 2025

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Review Open Access

The role of ferroptosis in Alzheimer's disease: Mechanisms and therapeutic potential (Review)

Heng Zeng, Zhaohui Jin
Article Number: 192
Published online on: 02 May 2025

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Studies on the functional role of UFMylation in cells (Review)

Rong Qin, Yu Tang, Yuhang Yuan, Fangyu Meng, Kepu Zheng, Xingyu Yang, Jiumei Zhao, Chuanhua Yang
Article Number: 191
Published online on: 02 May 2025

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Article Open Access

Effect of xylitol on low‑density lipoprotein‑stimulated oxidative stress in THP‑1 cells

Zile Huang, Anke Li, Rui Huang, Mengmeng Shi, Rujing Yang, Wenyan Wang, Zhen Huang, Yanhong Liu, Junzhu Wu
Article Number: 190
Published online on: 02 May 2025

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Article Open Access

LCMR1 deficiency exacerbates LPS‑induced lung injury in lung‑on‑a‑chip and mouse models

Zhenfei Mo, Chengcheng Su, Jinxia Liu, Jiabo Ren, Lu Liu, Yueming Wang, Yanqin Li, Chunsun Li, Zhen Yang, Xiuqing Ma, Liangan Chen
Article Number: 189
Published online on: 02 May 2025

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Article Open Access

CXCL9 is a dual‑role biomarker in colorectal cancer linked to mitophagy and modulated by ALKBH5

Geng Hu, Shijun Shen, Mingchao Zhu
Article Number: 188
Published online on: 02 May 2025

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Review Open Access

Barcodes based on nucleic acid sequences: Applications and challenges (Review)

Ying Hong Wei, Faquan Lin
Article Number: 187
Published online on: 02 May 2025

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Article Open Access

Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway

Meng-Qing Ma, Chun Yang, Shi-Yu Jin, Yu Yang, Yan-Yan Pan, Xian-He Lin
Article Number: 186
Published online on: 02 May 2025

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Article Open Access

NLRP3 inflammasome expression affects immune cell infiltration and clinical prognosis in Helicobacter pylori infection‑associated gastric cancer

Chuandan Wan, Yeqiong Xu, Yanping Zhu, Xuexian Cao, Ping Wang, Yulan Gu
Article Number: 185
Published online on: 28 April 2025

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Retraction Open Access

[Retracted] Triptolide inhibits migration and proliferation of fibroblasts from ileocolonic anastomosis of patients with Crohn’s disease via regulating the miR‑16‑1/HSP70 pathway

Min Chen, Jin-Min Wang, Dong Wang, Rong Wu, Hong-Wei Hou
Article Number: 184
Published online on: 28 April 2025

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Article Open Access

Treatment with human placental extracts inhibits allergic rhinitis by modulating AMPK/SHP1/SHP2/STING signaling

Beibei Wo, Shuang Liu, Zihui Liang, Xiaoming Li
Article Number: 183
Published online on: 25 April 2025

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Article Open Access

CDK5 targets p21CIP1 to regulate thyroid cancer cell proliferation and malignancy in patients

Min-Che Tung, Muhammet Oner, Shiuan-Woei Soong, Pang-Ting Cheng, Yu-Hsuan Li, Mei-Chih Chen, Chen-Kai Chou, Hong-Yo Kang, Frank Cheau-Feng Lin, Stella Chin-Shaw Tsai, Ho Lin
Article Number: 182
Published online on: 24 April 2025

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Review Open Access

The role of ICG NIRL fluorescence imaging in the surgical treatment of digestive system tumors (Review)

Yanxia Hu, Tingyuan Wen, Biguang Tuo
Article Number: 181
Published online on: 23 April 2025

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Article Open Access

Antcin K inhibits chondrosarcoma motility by reducing MMP‑7 expression via downregulation of the PI3K, Akt, mTOR and NF‑κB signaling pathway

Yat-Yin Law, Nguyen Bao Tran, Chang-Yu Song, Yu-Ying Wu, Hsien-Te Chen, Yi-Chin Fong, Hsiao-Chi Tsai, Yueh-Hsiung Kuo, Chih-Hsin Tang
Article Number: 180
Published online on: 23 April 2025

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Article Open Access

Sevoflurane: A dual modulator of miR‑211‑5p and mitochondrial apoptosis in glioma therapy

Haili Wang, Guofang Cheng, Shuyuan Zhang, Haibo Qu, Xibo Zhao, Ailing Yang, Xuejia Sun, Hua Pan
Article Number: 179
Published online on: 23 April 2025

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Retraction Open Access

[Retracted] MicroRNA‑195 suppresses rectal cancer growth and metastasis via regulation of the PI3K/AKT signaling pathway

Yeli Wang, Linsong Mu, Miaoling Huang
Article Number: 178
Published online on: 23 April 2025

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Article Open Access

Understanding the role of iron/heme metabolism in the anti‑inflammatory effects of natural sulfur molecules against lipopolysaccharide‑induced inflammation

Dong Young Kang, Se Won Bae, Kyoung-Jin Jang
Article Number: 177
Published online on: 17 April 2025

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Review Open Access

Anticancer effects of salvianolic acid A through multiple signaling pathways (Review)

Cheng-Xia Li, Qi Xu, Shi-Ting Jiang, Dan Liu, Chao Tang, Wen-Li Yang
Article Number: 176
Published online on: 17 April 2025

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Article Open Access

Transcriptomic profiling of autophagy and apoptosis pathways in liver cancer cells treated with a new tyrosine kinase inhibitor PD161570

Xingxing He, Jianping Liu, Yulian Zhang, Bushan Xie
Article Number: 175
Published online on: 16 April 2025

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Review Open Access

Action and mechanisms of neferine in inflammatory diseases (Review)

Qin Zhang, Qiaoling Zhou, Huihui Li
Article Number: 174
Published online on: 16 April 2025

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Retraction Open Access

[Retracted] Effect of selective inhibition or activation of PGE2 EP1 receptor on glomerulosclerosis

Xu Chen, Jun Yin, Yuyin Xu, Zhi Qiu, Jing Liu, Xiaolan Chen
Article Number: 173
Published online on: 15 April 2025

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Review Open Access

The role of Bcl‑2 in controlling the transition between autophagy and apoptosis (Review)

Ahmet Alperen Palabiyik
Article Number: 172
Published online on: 15 April 2025

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Article Open Access

Inhibitory effects of umbelliferone on carbon tetrachloride-induced hepatic fibrosis in rats through the TGF‑β1‑Smad signaling pathway

Lijuan Liang, Zhiheng Dong, Ziqing Shen, Yifan Zang, Wenlong Yang, Lan Wu, Lidao Bao
Article Number: 171
Published online on: 14 April 2025

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Correction Open Access

[Corrigendum] Heat shock protein 22: A new direction for cardiovascular disease (Review)

Yi Chen, Meng Li, Yanqing Wu
Article Number: 170
Published online on: 14 April 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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Article Open Access

PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Article Open Access

Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Article Open Access

Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Circular RNAs in intervertebral disc degeneration: Current insights into mechanisms and therapeutic potentials (Review)

Luyan Wang, Ke Yang, Houjun Zhu, Dachuan Wang, Feng Wang, Xianfa Du
Article Number: 111
Published online on: 05 February 2026

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Review Open Access

T‑cadherin and its impact on human diseases (Review)

Yan Song, Xinyi Wang, Yunfei Bian
Article Number: 110
Published online on: 05 February 2026

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Review

CD20 monoclonal antibody‑rituximab for the treatment of diffuse alveolar hemorrhage in children (Review)

Xiaobo Zhang, Xiao Wu, Yan Li, Guangmin Nong
Article Number: 109
Published online on: 05 February 2026

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Article Open Access

N6‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine

Jieyao Li, Qingsheng Xie, Jihao Xu
Article Number: 108
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin‑induced VEGF expression

Goutam Chakraborty, Shalini Jain, Smita Kale, Remya Raja, Santosh Kumar, Rosalin Mishra, Gopal C. Kundu
Article Number: 107
Published online on: 04 February 2026

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Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Article Open Access

Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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