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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2015 Volume 35 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Function of α-synuclein and PINK1 in Lewy body dementia (Review)

Akari Minami, Atsuko Nakanishi, Satoru Matsuda, Yasuko Kitagishi, Yasunori Ogura
Pages: 3-9
Published online on: 27 October 2014

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Review

PI3K/AKT/PTEN pathway as a target for Crohn's disease therapy (Review)

Nana Tokuhira, Yasuko Kitagishi, Miho Suzuki, Akari Minami, Atsuko Nakanishi, Yuna Ono, Keiko Kobayashi, Satoru Matsuda, Yasunori Ogura
Pages: 10-16
Published online on: 27 October 2014

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Review

Composite peptide‑based vaccines for cancer immunotherapy (Review)

Jie Yang, Qing Zhang, Ke Li, Hong Yin, Jun‑Nian Zheng
Pages: 17-23
Published online on: 12 November 2014

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Article Open Access

TP53/p53 alterations and Aurora A expression in progressor and non‑progressor colectomies from patients with longstanding ulcerative colitis

Mariann Friis-Ottessen, Espen Burum-Auensen, Aasa R. Schjølberg, Per  Olaf Ekstrøm, Solveig N. Andersen, Ole Petter Clausen, Paula M. De Angelis
Pages: 24-30
Published online on: 20 October 2014

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Article Open Access

Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo

Xiujuan Shi, Guangfeng Chen, Xiaoqiang Liu, Yu Qiu, Shuzhang Yang, Yan Zhang, Xuexun Fang, Chen Zhang, Xiaoqing Liu
Pages: 31-38
Published online on: 12 November 2014

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Article Open Access

Profiling of alternative polyadenylation sites in luminal B breast cancer using the SAPAS method

Xinmei Wang, Mingyue Li, Yingchun Yin, Liang Li, Yuqian Tao, Dengguo Chen, Jianzhao Li, Hongmei Han, Zhenbo Hou, Baohua Zhang, Xinyun Wang, Yu Ding, Haiyan Cui, Hengming Zhang
Pages: 39-50
Published online on: 20 October 2014

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Article Open Access

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

Giulia Montagner, Chiara Gemmo, Enrica Fabbri, Alex Manicardi, Igea Accardo, Nicoletta Bianchi, Alessia Finotti, Giulia Breveglieri, Francesca Salvatori, Monica Borgatti, Ilaria Lampronti, Alberto Bresciani, Sergio Altamura, Roberto Corradini, Roberto Gambari
Pages: 51-58
Published online on: 14 November 2014

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Article Open Access

miRNA-130b is required for the ERK/FOXM1 pathway activation-mediated protective effects of isosorbide dinitrate against mesenchymal stem cell senescence induced by high glucose

Jianfeng Xu, Zheyong Huang, Li Lin, Mingqiang Fu, Yanan Song, Yunli Shen, Daoyuan Ren, Yanhua Gao, Yangang Su, Yunzeng Zou, Yueguang Chen, Dadong Zhang, Wei Hu, Juying Qian, Junbo Ge
Pages: 59-71
Published online on: 29 October 2014

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Article Open Access

A novel Alu-based real-time PCR method for the quantitative detection of plasma circulating cell-free DNA: Sensitivity and specificity for the diagnosis of myocardial infarction

Xiaoli Lou, Yanqiang Hou, Dongyu Liang, Liang Peng, Hongwei Chen, Shanyuan Ma, Lurong Zhang
Pages: 72-80
Published online on: 05 November 2014

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Article Open Access

Differential expression of circulating miRNAs in maternal plasma in pregnancies with fetal macrosomia

Qinyu Ge, Yanan Zhu, Hailing Li, Fei Tian, Xueying Xie, Yunfei Bai
Pages: 81-91
Published online on: 31 October 2014

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Article Open Access

Integrative genomic analyses of a novel cytokine, interleukin-34 and its potential role in cancer prediction

Bo Wang, Wenming Xu, Miaolian Tan, Yan Xiao, Haiwei Yang, Tian-Song Xia
Pages: 92-102
Published online on: 12 November 2014

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Article Open Access

Influence of Panax ginseng on the offspring of adult rats exposed to prenatal stress

Young Ock Kim, Hwa-Young Lee, Hansol Won, Seong-Su Nah, Hyung-Ki Kim, Jun-Tack Kwon, Hak-Jae Kim
Pages: 103-109
Published online on: 13 November 2014

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Article

Synoviolin inhibitor LS-102 reduces endoplasmic reticulum stress-induced collagen secretion in an in vitro model of stress-related interstitial pneumonia

Fukami Nakajima, Satoko Aratani, Hidetoshi Fujita, Naoko Yagishita, Shizuko Ichinose, Koshi Makita, Yasuhiro Setoguchi, Toshihiro Nakajima
Pages: 110-116
Published online on: 27 October 2014

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Article

Epigallocatechin‑3‑gallate induces the apoptosis of hepatocellular carcinoma LM6 cells but not non‑cancerous liver cells

Yunjuan Zhang, Wei Duan, Lawrence Owusu, Dachang Wu, Yi Xin
Pages: 117-124
Published online on: 31 October 2014

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Article

Optimization of the isolation and enrichment of S-nitrosylated proteins from brain tissues of rodents and humans with various prion diseases for iTRAQ-based proteomics

Li-Na Chen, Qi Shi, Xiao-Mei Zhang, Bao-Yun Zhang, Yan Lv, Cao Chen, Jie Zhang, Kang Xiao, Chan Tian, Chen Gao, Xiao-Ping Dong
Pages: 125-134
Published online on: 22 October 2014

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Article

Vaccarin attenuates the human EA.hy926 endothelial cell oxidative stress injury through inhibition of Notch signaling

Fengshan Xie, Weiwei Cai, Yanling Liu, Yue Li, Bin Du, Lei Feng, Liying Qiu
Pages: 135-142
Published online on: 23 October 2014

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Article

MicroRNA expression profiles in rats with selenium deficiency and the possible role of the Wnt/β‑catenin signaling pathway in cardiac dysfunction

Yujie Xing, Zhongwei Liu, Guang Yang, Dengfeng Gao, Xiaolin Niu
Pages: 143-152
Published online on: 23 October 2014

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Article

Electromagnetic fields and nanomagnetic particles increase the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

Min-Ok Kim, Hyun Jung, Soo-Chan Kim, Jung-Keug Park, Young-Kwon Seo
Pages: 153-160
Published online on: 24 October 2014

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Article

The efficiency of the in vitro osteo/dentinogenic differentiation of human dental pulp cells, periodontal ligament cells and gingival fibroblasts

Jung-Kwon Choi, Hyo-In Hwang, Young-Joo Jang
Pages: 161-168
Published online on: 29 October 2014

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Article

Subretinal injection of amyloid-β peptide accelerates RPE cell senescence and retinal degeneration

Chaoqi Liu, Lining Cao, Shuai Yang, Linxinyu Xu, Pei Liu, Fang Wang, Ding Xu
Pages: 169-176
Published online on: 10 November 2014

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Article

Exogenous H2S protects H9c2 cardiac cells against high glucose-induced injury and inflammation by inhibiting the activation of the NF-κB and IL-1β pathways

Wenming Xu, Jingfu Chen, Jianchong Lin, Donghong Liu, Liqiu Mo, Wanying Pan, Jianqiang Feng, Wen Wu, Dongdan Zheng
Pages: 177-186
Published online on: 19 November 2014

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Article

Cinnamomum cassia bark produced by solid-state fermentation with Phellinus baumii has the potential to alleviate atopic dermatitis-related symptoms

Yong‑Kyu Shin, Hyeong‑U Son, Jong‑Myung Kim, Jin‑Chul Heo, Sang‑Han Lee, Jong‑Guk Kim
Pages: 187-194
Published online on: 18 November 2014

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Article

Activation of PPARγ by 12/15‑lipoxygenase during cerebral ischemia‑reperfusion injury

Jing Han, Li Sun, Yanwei Xu, Hao Liang, Yan Cheng
Pages: 195-201
Published online on: 12 November 2014

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Article

Veratric acid inhibits iNOS expression through the regulation of PI3K activation and histone acetylation in LPS-stimulated RAW264.7 cells

Woo-Suk Choi, Yong-Bae Seo, Pyung-Gyun Shin, Woe-Yeon Kim, Sang Yeol Lee, Young-Ju Choi, Gun-Do Kim
Pages: 202-210
Published online on: 27 October 2014

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Article

Essential oils and isolated compounds from Lippia alba leaves and flowers: Antimicrobial activity and osteoclast apoptosis

Paulo José Lima Juiz, Angelica Maria Lucchese, Roberto Gambari, Roberta Piva, Letizia Penolazzi, Martina Di Ciano, Ana Paula Trovatti Uetanabaro, Franceli Silva, Mario Julio Avila-Campos
Pages: 211-217
Published online on: 10 November 2014

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Article

Taurine induces the apoptosis of breast cancer cells by regulating apoptosis-related proteins of mitochondria

Xiali Zhang, Hongfei Lu, Yibing Wang, Chunju Liu, Weifeng Zhu, Shuangyan Zheng, Fusheng Wan
Pages: 218-226
Published online on: 13 November 2014

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Article

Low-dose γ-irradiation induces dual radio-adaptive responses depending on the post-irradiation time by altering microRNA expression profiles in normal human dermal fibroblasts

Seunghee Bae, Karam Kim, Hwa Jun Cha, Yeongmin Choi, Shang Hun Shin, In-Sook An, Jae Ho Lee, Su Jae Lee, Ji Young Kim, Seon Young Nam, Sungkwan An
Pages: 227-237
Published online on: 10 November 2014

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Article

Epigenetic silencing of HDAC1 by miR-449a upregulates Runx2 and promotes osteoblast differentiation

Te Liu, Lengchen Hou, Yanhui Zhao, Yongyi Huang
Pages: 238-246
Published online on: 14 November 2014

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Article

Withaferin A induces apoptosis through the generation of thiol oxidation in human head and neck cancer cells

Jong Won Park, Kyoung-Jin Min, Dong Eun Kim, Taeg Kyu Kwon
Pages: 247-252
Published online on: 27 October 2014

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Article

Validation of three splice donor and three splice acceptor sites for regulating four novel low-abundance spliced transcripts of human cytomegalovirus UL21.5 gene locus

Shuang Gao, Qiang Ruan, Yanping Ma, Mali Li, Lin Wang, Bo Zheng, Ying Qi, Yaohua Ji, Zhengrong Sun, Yujing Huang
Pages: 253-262
Published online on: 31 October 2014

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Article

Sulindac attenuates valproic acid-induced oxidative stress levels in primary cultured cortical neurons and ameliorates repetitive/stereotypic-like movement disorders in Wistar rats prenatally exposed to valproic acid

Yinghua Zhang, Cailing Yang, Guoyan Yuan, Zhongping Wang, Weigang Cui, Ruixi Li
Pages: 263-270
Published online on: 10 November 2014

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Article

Chemical and mass spectrometry characterization of the red alga Pyropia yezoensis chemoprotective protein (PYP): Protective activity of the N‑terminal fragment of PYP1 against acetaminophen‑induced cell death in Chang liver cells

Youn Hee Choi, Kenichi Yamaguchi, Tatsuya Oda, Taek Jeong Nam
Pages: 271-276
Published online on: 05 November 2014

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Article

Effects of PTEN on the longevity of cultured human umbilical vein endothelial cells: The role of antioxidants

Izak S. Tait, Yan Li, Jun Lu
Pages: 277-284
Published online on: 12 November 2014

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Article

Prostaglandin E2 EP1 receptor enhances TGF‑β1-induced mesangial cell injury

Xu Chen, Daishan Jiang, Jing Wang, Xiaolan Chen, Xiaolin Xu, Peipei Xi, Yaping Fan, Xiaoyan Zhang, Youfei Guan
Pages: 285-293
Published online on: 24 October 2014

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Retraction Open Access

[Retracted] Adseverin knockdown inhibits osteoclastogenesis in RAW264.7 cells.

Wenting Qi, Yan Gao, Jun Tian, Hongwei Jiang
Pages: 294-294
Published online on: 05 November 2014

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Article Open Access

Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Article Open Access

Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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Article Open Access

ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Review Open Access

Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Review Open Access

Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Review Open Access

Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Review Open Access

Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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Article Open Access

4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Review Open Access

Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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Review Open Access

m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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Article Open Access

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Review Open Access

Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Review Open Access

Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Review Open Access

Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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June-2026 Volume 57 Issue 6

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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