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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2022 Volume 25 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

miR‑374c‑5p regulates PTTG1 and inhibits cell growth and metastasis in hepatocellular carcinoma by regulating epithelial‑mesenchymal transition

Gang Yang, Yongfu Xiog, Guan Wang, Weinan Li, Tao Tang, Ji Sun, Jingdong Li
Article Number: 148
Published online on: 01 March 2022

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Review Open Access

Systemic inflammatory response syndrome is triggered by mitochondrial damage (Review)

Can Kong, Wei Song, Tao Fu
Article Number: 147
Published online on: 01 March 2022

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Article Open Access

Lack of an association between SCFD1 rs10139154 polymorphism and amyotrophic lateral sclerosis

Vasileios Siokas, Athina-Maria Aloizou, Ioannis Liampas, Christos Bakirtzis, Grigorios Nasios, Konstantinos Paterakis, Markos Sgantzos, Dimitrios P. Bogdanos, Demetrios A. Spandidos, Aristidis Tsatsakis, Panayiotis D. Mitsias, Efthimios Dardiotis
Article Number: 146
Published online on: 01 March 2022

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Retraction Open Access

[Retracted] MicroRNA‑137 has a suppressive role in liver cancer via targeting EZH2

Shichang Cui, Yanlei Sun, Yang Liu, Chengbiao Liu, Jinbao Wang, Guang Hao, Qidong Sun
Article Number: 145
Published online on: 01 March 2022

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Article Open Access

SIRT3 regulates bronchial epithelium apoptosis and aggravates airway inflammation in asthma

Jie Song, Jinxiang Wang
Article Number: 144
Published online on: 28 February 2022

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Article Open Access

LKB1 alleviates high glucose‑ and high fat‑induced inflammation and the expression of GnRH and sexual precocity‑related genes, in mouse hypothalamic cells by activating the AMPK/FOXO1 signaling pathway

Hui Liu, Limei Guan, Qing Zhou, Hailong Huang, Liangpu Xu
Article Number: 143
Published online on: 28 February 2022

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Correction Open Access

[Corrigendum] Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway

Yongheng Bai, Cunzao Wu, Weilong Hong, Xing Zhang, Leping Liu, Bicheng Chen
Article Number: 142
Published online on: 25 February 2022

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Article Open Access

Clinical survey of a pedigree with hereditary multiple exostoses and identification of EXT‑2 gene deletion mutation

Wentao Wang, Mingyuan Yang, Yuhang Shen, Kai Chen, Donghua Wu, Changwei Yang, Jinyi Bai, Dawei He, Jun Gao
Article Number: 141
Published online on: 24 February 2022

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Article Open Access

Advanced glycation end products promote osteoporosis by inducing ferroptosis in osteoblasts

Weiwei Ge, Jian Jie, Jie Yao, Wei Li, Yahui Cheng, Wenjuan Lu
Article Number: 140
Published online on: 24 February 2022

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Article

lncRNA TUG1 protects intestinal epithelial cells from damage induced by high glucose and high fat via AMPK/SIRT1

Weiwei Wei, Xingquan Wang, Yaqing Wei, Shilin Liu, Shengyu Gao, Hao Tian, Dewang Su
Article Number: 139
Published online on: 24 February 2022

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Article Open Access

Protein expression of transmembrane protease serine 4 in the gastrointestinal tract and in healthy, cancer, and SARS‑CoV‑2 infected lungs

Rachel Kerslake, Harpal S. Randeva, Danny Jonigk, Christopher Werlein, Jan L. Robertus, Periklis Katopodis, Petra Jasker, Demetrios A. Spandidos, Ioannis Kyrou, Emmanouil Karteris
Article Number: 138
Published online on: 24 February 2022

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Article Open Access

Propofol postconditioning alleviates diabetic myocardial ischemia‑reperfusion injury via the miR‑200c‑3p/AdipoR2/STAT3 signaling pathway

Lijun Huang, Li Ding, Shenghui Yu, Xin Huang, Qiusheng Ren
Article Number: 137
Published online on: 22 February 2022

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Article

Overactivation of IL6 cis‑signaling in leukocytes is an inflammatory hallmark of deep vein thrombosis

Rossella Salemi, Barbara Tomasello, Giuseppe Gattuso, Salvatore Santo Signorelli, Saverio Candido
Article Number: 136
Published online on: 22 February 2022

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Retraction Open Access

[Retracted] MicroRNA‑503 inhibits the proliferation and invasion of breast cancer cells via targeting insulin‑like growth factor 1 receptor

Jingwang Yan, Yonghuan Xu, Haipeng Wang, Taiping Du, Hao Chen
Article Number: 135
Published online on: 21 February 2022

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Article Open Access

Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation

Lulu Song, Xingxing Li, Qingwan Sun, Yifeng Zhao
Article Number: 134
Published online on: 18 February 2022

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Article Open Access

NR3C2 suppresses the proliferation, migration, invasion and angiogenesis of colon cancer cells by inhibiting the AKT/ERK signaling pathway

Jia Li, Zhao Xu
Article Number: 133
Published online on: 18 February 2022

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Article Open Access

Omentin‑1 induces osteoblast viability and differentiation via the TGF‑β/Smad signaling pathway in osteoporosis

Cuisong Tang, Dengpan Liang, Yuyou Qiu, Jingqi Zhu, Guangyu Tang
Article Number: 132
Published online on: 17 February 2022

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Article Open Access

A de novo mutation of SALL4 in a Chinese family with Okihiro syndrome

Xiuli Ma, Rui Huang, Guo Li, Tiesong Zhang, Jing Ma
Article Number: 131
Published online on: 17 February 2022

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Article Open Access

Ferroptosis inhibitor ferrostatin‑1 alleviates homocysteine‑induced ovarian granulosa cell injury by regulating TET activity and DNA methylation

Qing Shi, Rui Liu, Li Chen
Article Number: 130
Published online on: 15 February 2022

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Article Open Access

Primary bile acid activates Egr‑1 expression through the MAPK signaling pathway in gastric cancer

Su-Mi Lee, Moon Sik Park, Seon-Young Park, Yoo-Duk Choi, Jin Ook Chung, Dong Hyun Kim, Young Do Jung, Hyun Soo Kim
Article Number: 129
Published online on: 15 February 2022

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Article Open Access

Regulation of dendrite growth by Cdc42 effector protein‑4 in hippocampal neurons in vitro

Lei Hou, Lufeng Wang, Zhijie Zhao, Wei Xu, Yang Wang, Gang Cui
Article Number: 128
Published online on: 15 February 2022

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Retraction Open Access

[Retracted] MicroRNA‑101 inhibits the proliferation and invasion of bladder cancer cells via targeting c‑FOS

Yongqi Long, Zhiping Wu, Xinhua Yang, Lei Chen, Zhijun Han, Yulong Zhang, Jinge Liu, Wenjin Liu, Xinyi Liu
Article Number: 127
Published online on: 14 February 2022

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Icariin attenuates thioacetamide‑induced bone loss via the RANKL‑p38/ERK‑NFAT signaling pathway

Linyan Cheng, Xiaoli Jin, Hao Shen, Xuanwei Chen, Jin Chen, Bin Xu, Jian Xu
Article Number: 126
Published online on: 14 February 2022

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Article

Inhibitory effect of membrane‑free stem cell components derived from adipose tissues on skin inflammation in keratinocytes

Sang Eun Ha, Preethi Vetrivel, Seong Min Kim, Pritam Bhagwan Bhosale, Hun Hwan Kim, Jung Eun Pak, Jeong Doo Heo, Young Sil Kim, Gon Sup Kim
Article Number: 125
Published online on: 14 February 2022

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Article Open Access

Methylation‑associated inactivation of JPH3 and its effect on prognosis and cell biological function in HCC

Yi Huang, Zhou Yu, Min Zheng, Xiaohong Yang, Honglan Huang, Lijin Zhao
Article Number: 124
Published online on: 14 February 2022

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Article Open Access

Knockdown of long non‑coding RNA DDX11‑AS1 inhibits the proliferation, migration and paclitaxel resistance of breast cancer cells by upregulating microRNA‑497 expression

Meng Liang, Beibei Zhu, Min Wang, Ju Jin
Article Number: 123
Published online on: 11 February 2022

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Article Open Access

Ophiopogonin‑B targets PTP1B to inhibit the malignant progression of hepatocellular carcinoma by regulating the PI3K/AKT and AMPK signaling pathways

Fang Yuan, Qian Gao, Hailin Tang, Jun Shi, Yiqun Zhou
Article Number: 122
Published online on: 11 February 2022

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Article Open Access

Donepezil ameliorates oxygen‑glucose deprivation/reoxygenation‑induced cardiac microvascular endothelial cell dysfunction through PARP1/NF‑κB signaling

Yuan Li, Xiuzhen Sun, Jianqun Zhuang, Junzhi Wang, Chunqiang Yang
Article Number: 121
Published online on: 10 February 2022

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Article Open Access

Expression of SOX2OT, DANCR and TINCR long non‑coding RNAs in papillary thyroid cancer and its effects on clinicopathological features

Fadime Mutlu Icduygu, Egemen Akgun, Demet Sengul, Asuman Ozgoz, Ebru Alp
Article Number: 120
Published online on: 10 February 2022

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Article

Exosomes derived from the blood of patients with sepsis regulate apoptosis and aerobic glycolysis in human myocardial cells via the hsa‑miR‑1262/SLC2A1 signaling pathway

Fangyuan Sun, Huan Geng, Yuxia Sun, Wentao Feng, Tianning Tian, Liang Ye, Ming Lei
Article Number: 119
Published online on: 08 February 2022

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Article Open Access

Ferroptosis‑related long non‑coding RNAs and the roles of LASTR in stomach adenocarcinoma

Gongjun Wang, Libin Sun, Shasha Wang, Jing Guo, Ruoxi Xiao, Wenqian Li, Weiwei Qi, Wensheng Qiu
Article Number: 118
Published online on: 08 February 2022

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Article Open Access

GINS2 regulates the proliferation and apoptosis of colon cancer cells through PTP4A1

Hao Hu, Lina Ye, Zhe Liu
Article Number: 117
Published online on: 08 February 2022

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Article Open Access

Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis

Bingqing Bai, Huihui Li, Liang Han, Yongyu Mei, Cui Hu, Qiao Mei, Jianming Xu, Xiaochang Liu
Article Number: 116
Published online on: 07 February 2022

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Article Open Access

IL‑1β‑induced pentraxin 3 inhibits the proliferation, invasion and cell cycle of trophoblasts in preeclampsia and is suppressed by IL‑1β antagonists

Xiaoxi Wang, Jing Zhang, Jing Ji
Article Number: 115
Published online on: 07 February 2022

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Retraction Open Access

[Retracted] Knockdown of PREX2a inhibits the malignant phenotype of osteosarcoma cells

Zixun Dai, Jie Xie, Pengfei Lei, Yihe Hu
Article Number: 114
Published online on: 07 February 2022

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Article Open Access

Inhibitory effects and underlying mechanisms of Artemisia capillaris essential oil on melanogenesis in the B16F10 cell line

Min Jae Kim, Elsayed A. Mohamed, Da Som Kim, Mi-Jin Park, Byoung-Jun Ahn, Eui-Bae Jeung, Beum-Soo An
Article Number: 113
Published online on: 04 February 2022

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Article Open Access

Molecular mechanism of atractylon in the invasion and migration of hepatic cancer cells based on high‑throughput sequencing Retraction in /10.3892/mmr.2024.13373

Yang Cheng, Jian Ping, Jianjie Chen, Yifei Fu, Hui Zhao, Jiahua Xue
Article Number: 112
Published online on: 02 February 2022

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Article Open Access

Exenatide exerts a neuroprotective effect against diabetic cognitive impairment in rats by inhibiting apoptosis: Role of the JNK/c‑JUN signaling pathway

Gengyin Wang, Zongquan Zhao, Bo Ren, Wu Yu, Xudong Zhang, Jiang Liu, Liping Wang, Daowen Si, Meiliu Yang
Article Number: 111
Published online on: 02 February 2022

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Article Open Access

Dynamic effects of chronic unpredictable mild stress on the hippocampal transcriptome in rats

Feng Li, Ying Wang, Xue Wang, Yun Zhao, Fang Xie, Ling-Jia Qian
Article Number: 110
Published online on: 01 February 2022

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Review Open Access

Effects of transcranial magnetic stimulation on neurobiological changes in Alzheimer's disease (Review)

Shahid Bashir, Mohammad Uzair, Turki Abualait, Muhammad Arshad, Roaa A. Khallaf, Asim Niaz, Ziyad Thani, Woo-Kyoung Yoo, Isaac Túnez, Asli Demirtas‑Tatlidede, Sultan Ayoub Meo
Article Number: 109
Published online on: 01 February 2022

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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