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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2022 Volume 25 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

miR‑374c‑5p regulates PTTG1 and inhibits cell growth and metastasis in hepatocellular carcinoma by regulating epithelial‑mesenchymal transition

Gang Yang, Yongfu Xiog, Guan Wang, Weinan Li, Tao Tang, Ji Sun, Jingdong Li
Article Number: 148
Published online on: 01 March 2022

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Review Open Access

Systemic inflammatory response syndrome is triggered by mitochondrial damage (Review)

Can Kong, Wei Song, Tao Fu
Article Number: 147
Published online on: 01 March 2022

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Article Open Access

Lack of an association between SCFD1 rs10139154 polymorphism and amyotrophic lateral sclerosis

Vasileios Siokas, Athina-Maria Aloizou, Ioannis Liampas, Christos Bakirtzis, Grigorios Nasios, Konstantinos Paterakis, Markos Sgantzos, Dimitrios P. Bogdanos, Demetrios A. Spandidos, Aristidis Tsatsakis, Panayiotis D. Mitsias, Efthimios Dardiotis
Article Number: 146
Published online on: 01 March 2022

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[Retracted] MicroRNA‑137 has a suppressive role in liver cancer via targeting EZH2

Shichang Cui, Yanlei Sun, Yang Liu, Chengbiao Liu, Jinbao Wang, Guang Hao, Qidong Sun
Article Number: 145
Published online on: 01 March 2022

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Article Open Access

SIRT3 regulates bronchial epithelium apoptosis and aggravates airway inflammation in asthma

Jie Song, Jinxiang Wang
Article Number: 144
Published online on: 28 February 2022

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Article Open Access

LKB1 alleviates high glucose‑ and high fat‑induced inflammation and the expression of GnRH and sexual precocity‑related genes, in mouse hypothalamic cells by activating the AMPK/FOXO1 signaling pathway

Hui Liu, Limei Guan, Qing Zhou, Hailong Huang, Liangpu Xu
Article Number: 143
Published online on: 28 February 2022

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Correction Open Access

[Corrigendum] Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway

Yongheng Bai, Cunzao Wu, Weilong Hong, Xing Zhang, Leping Liu, Bicheng Chen
Article Number: 142
Published online on: 25 February 2022

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Clinical survey of a pedigree with hereditary multiple exostoses and identification of EXT‑2 gene deletion mutation

Wentao Wang, Mingyuan Yang, Yuhang Shen, Kai Chen, Donghua Wu, Changwei Yang, Jinyi Bai, Dawei He, Jun Gao
Article Number: 141
Published online on: 24 February 2022

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Advanced glycation end products promote osteoporosis by inducing ferroptosis in osteoblasts

Weiwei Ge, Jian Jie, Jie Yao, Wei Li, Yahui Cheng, Wenjuan Lu
Article Number: 140
Published online on: 24 February 2022

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Article

lncRNA TUG1 protects intestinal epithelial cells from damage induced by high glucose and high fat via AMPK/SIRT1

Weiwei Wei, Xingquan Wang, Yaqing Wei, Shilin Liu, Shengyu Gao, Hao Tian, Dewang Su
Article Number: 139
Published online on: 24 February 2022

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Protein expression of transmembrane protease serine 4 in the gastrointestinal tract and in healthy, cancer, and SARS‑CoV‑2 infected lungs

Rachel Kerslake, Harpal S. Randeva, Danny Jonigk, Christopher Werlein, Jan L. Robertus, Periklis Katopodis, Petra Jasker, Demetrios A. Spandidos, Ioannis Kyrou, Emmanouil Karteris
Article Number: 138
Published online on: 24 February 2022

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Propofol postconditioning alleviates diabetic myocardial ischemia‑reperfusion injury via the miR‑200c‑3p/AdipoR2/STAT3 signaling pathway

Lijun Huang, Li Ding, Shenghui Yu, Xin Huang, Qiusheng Ren
Article Number: 137
Published online on: 22 February 2022

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Article

Overactivation of IL6 cis‑signaling in leukocytes is an inflammatory hallmark of deep vein thrombosis

Rossella Salemi, Barbara Tomasello, Giuseppe Gattuso, Salvatore Santo Signorelli, Saverio Candido
Article Number: 136
Published online on: 22 February 2022

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Retraction Open Access

[Retracted] MicroRNA‑503 inhibits the proliferation and invasion of breast cancer cells via targeting insulin‑like growth factor 1 receptor

Jingwang Yan, Yonghuan Xu, Haipeng Wang, Taiping Du, Hao Chen
Article Number: 135
Published online on: 21 February 2022

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Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation

Lulu Song, Xingxing Li, Qingwan Sun, Yifeng Zhao
Article Number: 134
Published online on: 18 February 2022

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NR3C2 suppresses the proliferation, migration, invasion and angiogenesis of colon cancer cells by inhibiting the AKT/ERK signaling pathway

Jia Li, Zhao Xu
Article Number: 133
Published online on: 18 February 2022

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Article Open Access

Omentin‑1 induces osteoblast viability and differentiation via the TGF‑β/Smad signaling pathway in osteoporosis

Cuisong Tang, Dengpan Liang, Yuyou Qiu, Jingqi Zhu, Guangyu Tang
Article Number: 132
Published online on: 17 February 2022

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A de novo mutation of SALL4 in a Chinese family with Okihiro syndrome

Xiuli Ma, Rui Huang, Guo Li, Tiesong Zhang, Jing Ma
Article Number: 131
Published online on: 17 February 2022

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Ferroptosis inhibitor ferrostatin‑1 alleviates homocysteine‑induced ovarian granulosa cell injury by regulating TET activity and DNA methylation

Qing Shi, Rui Liu, Li Chen
Article Number: 130
Published online on: 15 February 2022

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Primary bile acid activates Egr‑1 expression through the MAPK signaling pathway in gastric cancer

Su-Mi Lee, Moon Sik Park, Seon-Young Park, Yoo-Duk Choi, Jin Ook Chung, Dong Hyun Kim, Young Do Jung, Hyun Soo Kim
Article Number: 129
Published online on: 15 February 2022

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Regulation of dendrite growth by Cdc42 effector protein‑4 in hippocampal neurons in vitro

Lei Hou, Lufeng Wang, Zhijie Zhao, Wei Xu, Yang Wang, Gang Cui
Article Number: 128
Published online on: 15 February 2022

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Retraction Open Access

[Retracted] MicroRNA‑101 inhibits the proliferation and invasion of bladder cancer cells via targeting c‑FOS

Yongqi Long, Zhiping Wu, Xinhua Yang, Lei Chen, Zhijun Han, Yulong Zhang, Jinge Liu, Wenjin Liu, Xinyi Liu
Article Number: 127
Published online on: 14 February 2022

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Icariin attenuates thioacetamide‑induced bone loss via the RANKL‑p38/ERK‑NFAT signaling pathway

Linyan Cheng, Xiaoli Jin, Hao Shen, Xuanwei Chen, Jin Chen, Bin Xu, Jian Xu
Article Number: 126
Published online on: 14 February 2022

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Article

Inhibitory effect of membrane‑free stem cell components derived from adipose tissues on skin inflammation in keratinocytes

Sang Eun Ha, Preethi Vetrivel, Seong Min Kim, Pritam Bhagwan Bhosale, Hun Hwan Kim, Jung Eun Pak, Jeong Doo Heo, Young Sil Kim, Gon Sup Kim
Article Number: 125
Published online on: 14 February 2022

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Methylation‑associated inactivation of JPH3 and its effect on prognosis and cell biological function in HCC

Yi Huang, Zhou Yu, Min Zheng, Xiaohong Yang, Honglan Huang, Lijin Zhao
Article Number: 124
Published online on: 14 February 2022

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Knockdown of long non‑coding RNA DDX11‑AS1 inhibits the proliferation, migration and paclitaxel resistance of breast cancer cells by upregulating microRNA‑497 expression

Meng Liang, Beibei Zhu, Min Wang, Ju Jin
Article Number: 123
Published online on: 11 February 2022

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Ophiopogonin‑B targets PTP1B to inhibit the malignant progression of hepatocellular carcinoma by regulating the PI3K/AKT and AMPK signaling pathways

Fang Yuan, Qian Gao, Hailin Tang, Jun Shi, Yiqun Zhou
Article Number: 122
Published online on: 11 February 2022

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Donepezil ameliorates oxygen‑glucose deprivation/reoxygenation‑induced cardiac microvascular endothelial cell dysfunction through PARP1/NF‑κB signaling

Yuan Li, Xiuzhen Sun, Jianqun Zhuang, Junzhi Wang, Chunqiang Yang
Article Number: 121
Published online on: 10 February 2022

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Expression of SOX2OT, DANCR and TINCR long non‑coding RNAs in papillary thyroid cancer and its effects on clinicopathological features

Fadime Mutlu Icduygu, Egemen Akgun, Demet Sengul, Asuman Ozgoz, Ebru Alp
Article Number: 120
Published online on: 10 February 2022

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Article

Exosomes derived from the blood of patients with sepsis regulate apoptosis and aerobic glycolysis in human myocardial cells via the hsa‑miR‑1262/SLC2A1 signaling pathway

Fangyuan Sun, Huan Geng, Yuxia Sun, Wentao Feng, Tianning Tian, Liang Ye, Ming Lei
Article Number: 119
Published online on: 08 February 2022

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Ferroptosis‑related long non‑coding RNAs and the roles of LASTR in stomach adenocarcinoma

Gongjun Wang, Libin Sun, Shasha Wang, Jing Guo, Ruoxi Xiao, Wenqian Li, Weiwei Qi, Wensheng Qiu
Article Number: 118
Published online on: 08 February 2022

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GINS2 regulates the proliferation and apoptosis of colon cancer cells through PTP4A1

Hao Hu, Lina Ye, Zhe Liu
Article Number: 117
Published online on: 08 February 2022

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Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis

Bingqing Bai, Huihui Li, Liang Han, Yongyu Mei, Cui Hu, Qiao Mei, Jianming Xu, Xiaochang Liu
Article Number: 116
Published online on: 07 February 2022

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IL‑1β‑induced pentraxin 3 inhibits the proliferation, invasion and cell cycle of trophoblasts in preeclampsia and is suppressed by IL‑1β antagonists

Xiaoxi Wang, Jing Zhang, Jing Ji
Article Number: 115
Published online on: 07 February 2022

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Retraction Open Access

[Retracted] Knockdown of PREX2a inhibits the malignant phenotype of osteosarcoma cells

Zixun Dai, Jie Xie, Pengfei Lei, Yihe Hu
Article Number: 114
Published online on: 07 February 2022

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Inhibitory effects and underlying mechanisms of Artemisia capillaris essential oil on melanogenesis in the B16F10 cell line

Min Jae Kim, Elsayed A. Mohamed, Da Som Kim, Mi-Jin Park, Byoung-Jun Ahn, Eui-Bae Jeung, Beum-Soo An
Article Number: 113
Published online on: 04 February 2022

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Molecular mechanism of atractylon in the invasion and migration of hepatic cancer cells based on high‑throughput sequencing Retraction in /10.3892/mmr.2024.13373

Yang Cheng, Jian Ping, Jianjie Chen, Yifei Fu, Hui Zhao, Jiahua Xue
Article Number: 112
Published online on: 02 February 2022

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Exenatide exerts a neuroprotective effect against diabetic cognitive impairment in rats by inhibiting apoptosis: Role of the JNK/c‑JUN signaling pathway

Gengyin Wang, Zongquan Zhao, Bo Ren, Wu Yu, Xudong Zhang, Jiang Liu, Liping Wang, Daowen Si, Meiliu Yang
Article Number: 111
Published online on: 02 February 2022

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Dynamic effects of chronic unpredictable mild stress on the hippocampal transcriptome in rats

Feng Li, Ying Wang, Xue Wang, Yun Zhao, Fang Xie, Ling-Jia Qian
Article Number: 110
Published online on: 01 February 2022

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Review Open Access

Effects of transcranial magnetic stimulation on neurobiological changes in Alzheimer's disease (Review)

Shahid Bashir, Mohammad Uzair, Turki Abualait, Muhammad Arshad, Roaa A. Khallaf, Asim Niaz, Ziyad Thani, Woo-Kyoung Yoo, Isaac Túnez, Asli Demirtas‑Tatlidede, Sultan Ayoub Meo
Article Number: 109
Published online on: 01 February 2022

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Article

Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Review Open Access

Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Article Open Access

Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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Review Open Access

SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Review Open Access

Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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