Journal Articles
Review
Improving diagnosis, prognosis and prediction by using biomarkers in CRC patients (Review)
Taxiarchis Konstantinos Nikolouzakis, Loukia Vassilopoulou, Persefoni Fragkiadaki, Theodoros Mariolis Sapsakos, Georgios Z. Papadakis, Demetrios A. Spandidos, Aristides M. Tsatsakis, John Tsiaoussis
Pages: 2455-2472 Published online on: 21 March 2018
Review
Autophagy regulation and its dual role in blood cancers: A novel target for therapeutic development (Review)
Shenhe Jin, Juying Wei, Liangshun You, Hui Liu, Wenbin Qian
Pages: 2473-2481 Published online on: 13 April 2018
Article
Translational control of the undifferentiated phenotype in ER‑positive breast tumor cells: Cytoplasmic localization of ERα and impact of IRES inhibition
Christos Vaklavas, Kurt R. Zinn, Sharon L. Samuel, Zheng Meng, William E. Grizzle, Hyoungsoo Choi, Scott W. Blume
Pages: 2482-2498 Published online on: 23 March 2018
Article
Screening potential biomarkers for colorectal cancer based on circular RNA chips
Shuo Chen, Lin Zhang, Yinan Su, Xipeng Zhang
Pages: 2499-2512 Published online on: 16 April 2018
Article
Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis
Ying-Hui Kong, Su-Ping Xu
Pages: 2513-2526 Published online on: 18 April 2018
Article
Role of COL6A3 in colorectal cancer
Wei Liu, Li Li, Hua Ye, Huan Tao, Huaqin He
Pages: 2527-2536 Published online on: 23 March 2018
Article
Enrichment and mutation detection of circulating tumor cells from blood samples
Ruqin Kou, Jian Zhao, Priya Gogoi, Shannon Carskadon, Will Chow, Clara Hwang, Nallasivam Palanisamy, Conrad Leung, Yixin Wang
Pages: 2537-2544 Published online on: 30 March 2018
Article
Corilagin induces the apoptosis of hepatocellular carcinoma cells through the mitochondrial apoptotic and death receptor pathways
Yuan Deng, Xudan Li, Xuan Li, Zhizhong Zheng, Wen Huang, Lianghua Chen, Qingxuan Tong, Yanlin Ming
Pages: 2545-2552 Published online on: 23 April 2018
Article
Upregulation of UHRF1 promotes the progression of melanoma by inducing cell proliferation
Chuanyuan Wei, Nanhang Lu, Lu Wang, Yong Zhang, Zihao Feng, Yanwen Yang, Fazhi Qi, Jianying Gu
Pages: 2553-2562 Published online on: 04 April 2018
Article
MicroRNA-384 inhibits the progression of breast cancer by targeting ACVR1
Yongxia Wang, Zheying Zhang, Jianqiang Wang
Pages: 2563-2574 Published online on: 20 April 2018
Article
Downregulation of NONO induces apoptosis, suppressing growth and invasion in esophageal squamous cell carcinoma
Rui Cheng, Shengtao Zhu, Shuilong Guo, Li Min, Jie Xing, Qingdong Guo, Peng Li, Shutian Zhang
Pages: 2575-2583 Published online on: 27 March 2018
Article
Expression and oncogenic properties of membranous Notch1 in oral leukoplakia and oral squamous cell carcinoma
Xu Ding, Yang Zheng, Zhao Wang, Wei Zhang, Yibo Dong, Wantao Chen, Jiang Li, Weiming Chu, Yi Zhong, Li Mao, Xiaomeng Song, Yunong Wu
Pages: 2584-2594 Published online on: 27 March 2018
Article
Cucurbitacin D impedes gastric cancer cell survival via activation of the iNOS/NO and inhibition of the Akt signalling pathway
Yan Zhen Zhang, Chun Feng Wang, Lian Feng Zhang
Pages: 2595-2603 Published online on: 10 April 2018
Article
Protein arginine N-methyltransferase 2 reverses tamoxifen resistance in breast cancer cells through suppression of ER-α36
Yingying Shen, Jing Zhong, Jianghua Liu, Kehuang Liu, Jun Zhao, Ting Xu, Ting Zeng, Zhimei Li, Yajun Chen, Wenjun Ding, Gebo Wen, Xuyu Zu, Renxian Cao
Pages: 2604-2612 Published online on: 02 April 2018
Article
miR‑29a suppresses IL‑13‑induced cell invasion by inhibiting YY1 in the AKT pathway in lung adenocarcinoma A549 cells
Yu Zhang, Shujin He, Renmei Mei, Yurong Kang, Jing Duan, Ran Wei, Chuqi Xiang, Yemeng Wu, Xiangtong Lu, Zhenyu Cai, Lixia Xiong
Pages: 2613-2623 Published online on: 04 April 2018
Article
Effects of miR‑138‑5p and miR‑204‑5p on the migration and proliferation of gastric cancer cells by targeting EGFR Retraction in /10.3892/or.2023.8677
Yi Wang, Haiyang Zhang, Shaohua Ge, Qian Fan, Likun Zhou, Hongli Li, Ming Bai, Tao Ning, Rui Liu, Xia Wang, Ting Deng, Le Zhang, Guoguang Ying, Yi Ba
Pages: 2624-2634 Published online on: 23 April 2018
Article
miR‑30a inhibits epithelial‑mesenchymal transition and metastasis in triple‑negative breast cancer by targeting ROR1
Xin Wang, Huisi Qiu, Ruiming Tang, Huisheng Song, Huilin Pan, Zhengfu Feng, Longhua Chen
Pages: 2635-2643 Published online on: 18 April 2018
Article
MALAT1 affects ovarian cancer cell behavior and patient survival
Qunbo Lin, Wencai Guan, Weimin Ren, Lingyun Zhang, Jinguo Zhang, Guoxiong Xu
Pages: 2644-2652 Published online on: 19 April 2018
Article
Identifying genes as potential prognostic indicators in patients with serous ovarian cancer resistant to carboplatin using integrated bioinformatics analysis
Shi‑Jie Zhan, Bin Liu, Hua Linghu
Pages: 2653-2663 Published online on: 19 April 2018
Article
Significance of Lysyl oxidase‑like 2 gene expression on the epithelial‑mesenchymal status of hepatocellular carcinoma
Go Ninomiya, Suguru Yamada, Masamichi Hayashi, Shigeomi Takeda, Masaya Suenaga, Hideki Takami, Mitsuro Kanda, Naoki Iwata, Yukiko Niwa, Chie Tanaka, Daisuke Kobayashi, Tsutomu Fujii, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Yasuhiro Kodera
Pages: 2664-2672 Published online on: 02 April 2018
Article
Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation
Meng‑Yan Sun, Yuchong Wang, Ji Zhu, Chuan Lv, Kai Wu, Xin‑Wei Wang, Chun‑Yu Xue
Pages: 2673-2680 Published online on: 30 March 2018
Article
Laterally spreading features of gastrointestinal stromal tumors: A clinicopathological study
Susumu Matsukuma, Michinori Murayama, Yoshitaka Utsumi, Koji Sumi, Kosuke Miyai, Hiroaki Takeo
Pages: 2681-2687 Published online on: 10 April 2018
Article
TIPE attenuates the apoptotic effect of radiation and cisplatin and promotes tumor growth via JNK and p38 activation in Raw264.7 and EL4 cells
Yao Liu, Xiao Yan Ni, Rui Ling Chen, Juan Li, Feng Guang Gao
Pages: 2688-2694 Published online on: 03 April 2018
Article
A functional polymorphism at miR‑491‑5p binding site in the 3'UTR of MMP9 gene confers increased risk for pressure ulcers after hip fracture
Rui Yang, Li Han, Xiantie Zeng
Pages: 2695-2702 Published online on: 28 March 2018
Article
miR‑186 functions as a tumor suppressor in osteosarcoma cells by suppressing the malignant phenotype and aerobic glycolysis
Qianren Xiao, Zhihui Wei, Yunyun Li, Xin Zhou, Jiajun Chen, Tengyu Wang, Gaohai Shao, Minghua Zhang, Zhongzu Zhang
Pages: 2703-2710 Published online on: 23 April 2018
Article
β‑arrestin2 promotes 5‑FU‑induced apoptosis via the NF‑κB pathway in colorectal cancer
Weixia Ren, Tingting Wang, Xiangjun He, Qi Zhang, Jianhua Zhou, Fangfang Liu, Fangfang Gao, Yujun Zhang, Yulan Liu
Pages: 2711-2720 Published online on: 30 March 2018
Article
NIK‑ and IKKβ‑binding protein contributes to gastric cancer chemoresistance by promoting epithelial‑mesenchymal transition through the NF‑κB signaling pathway
Zhen‑Hua Fu, Shi‑Quan Liu, Meng‑Bin Qin, Jie‑An Huang, Chun‑Yan Xu, Wen‑Hong Wu, Li‑Ye Zhu, Nan Qin, Ming‑Yu Lai
Pages: 2721-2730 Published online on: 30 March 2018
Article
miR‑22‑3p enhances multi‑chemoresistance by targeting NET1 in bladder cancer cells
Jun Xiao, Sanqiang Niu, Jiahong Zhu, Lei Lv, Hui Deng, Daqing Pan, Deyun Shen, Congyun Xu, Zhou Shen, Tao Tao
Pages: 2731-2740 Published online on: 04 April 2018
Article
Effect of curcumin on the cell surface markers CD44 and CD24 in breast cancer
Gloria M. Calaf, Richard Ponce-Cusi, Jorge Abarca-Quinones
Pages: 2741-2748 Published online on: 20 April 2018
Article
Impact of RUNX2 gene silencing on the gemcitabine sensitivity of p53‑mutated pancreatic cancer MiaPaCa‑2 spheres
Meijie Sang, Mizuyo Nakamura, Takehiro Ogata, Dan Sun, Osamu Shimozato, Toshio Nikaido, Toshinori Ozaki
Pages: 2749-2758 Published online on: 30 March 2018
Article
CT‑1042, a novel anticancer agent, exhibits effects by activating p53 and inhibiting survivin
Jun Yang, Linna Li, Chengwang Xu, Dexuan Yang, Shanshan Wang, Shoujun Yuan
Pages: 2759-2768 Published online on: 04 April 2018
Article
Anthricin‑induced caspase‑dependent apoptosis through IGF1R/PI3K/AKT pathway inhibition in A549 human non‑small lung cancer cells
Bo‑Ram Park, Seul Ah Lee, Sung Min Moon, Chun Sung Kim
Pages: 2769-2776 Published online on: 27 March 2018
Article
Corosolic acid induces cell cycle arrest and cell apoptosis in human retinoblastoma Y-79 cells via disruption of MELK-FoxM1 signaling
Ke Wang, Xue Zhu, Yong Yao, Min Yang, Fanfan Zhou, Ling Zhu
Pages: 2777-2786 Published online on: 28 March 2018
Article
Autophagy inhibition potentiates SAHA‑mediated apoptosis in glioblastoma cells by accumulation of damaged mitochondria
Kovooru Lohitesh, Heena Saini, Abhilasha Srivastava, Sudeshna Mukherjee, Aniruddha Roy, Rajdeep Chowdhury
Pages: 2787-2796 Published online on: 16 April 2018
Article
Diallyl disulfide inhibits TGF‑β1‑induced upregulation of Rac1 and β‑catenin in epithelial‑mesenchymal transition and tumor growth of gastric cancer
Bo Su, Jian Su, Ying Zeng, En Ding, Fang Liu, Tuo Tan, Hong Xia, You‑Hua Wu, Xi Zeng, Hui Ling, Hao Jiang, Xiao‑Hong Ai, Qi Su
Pages: 2797-2806 Published online on: 30 March 2018
Article
Chloroquine inhibits cell growth in human A549 lung cancer cells by blocking autophagy and inducing mitochondrial‑mediated apoptosis
Likun Liu, Cuicui Han, Haitao Yu, Wenbin Zhu, Hongxia Cui, Lihong Zheng, Chunjing Zhang, Liling Yue
Pages: 2807-2816 Published online on: 12 April 2018
Article
Detection of survivin expression in bladder cancer and renal cell carcinoma using specific monoclonal antibodies
Dongmei Chen, Jianjun Xu, Qingyun Zhang
Pages: 2817-2828 Published online on: 05 April 2018
Article
Protein kinase, membrane‑associated tyrosine/threonine 1 is associated with the progression of colorectal cancer
Dongjun Jeong, Hyeongjoo Kim, Doyeon Kim, Seona Ban, Seunghyun Oh, Sanghee Ji, Donghuyn Kang, Hyunyong Lee, Tae Sung Ahn, Han Jo Kim, Sang Byung Bae, Moon Soo Lee, Chang‑Jin Kim, Hyog Young Kwon, Moo‑Jun Baek
Pages: 2829-2836 Published online on: 13 April 2018
Article
A novel monoclonal antibody targeting a novel epitope of VE‑cadherin inhibits vasculogenic mimicry of lung cancer cells
Jie Ding, Xi Jia, Bin Zuo, Jun He, Jianfeng Yang, Yang He
Pages: 2837-2844 Published online on: 16 April 2018
Article
Spermidine‑induced growth inhibition and apoptosis via autophagic activation in cervical cancer
Yu Chen, Haifeng Zhuang, Xuerui Chen, Zheqi Shi, Xu Wang
Pages: 2845-2854 Published online on: 18 April 2018
Article
Nodal induced by hypoxia exposure contributes to dacarbazine resistance and the maintenance of stemness in melanoma cancer stem‑like cells
Hong Li, Junjie Chen, Xiao Wang, Mei He, Zhenyu Zhang, Ying Cen
Pages: 2855-2864 Published online on: 23 April 2018
Article
Bioinformatics analysis of differentially expressed miRNA-related mRNAs and their prognostic value in breast carcinoma Corrigendum in /10.3892/or.2018.6505
Guo-Ming Zhang, Hemant Goyal, Lei-Lei Song
Pages: 2865-2872 Published online on: 23 April 2018
Article
Microvesicles shed from bortezomib-treated or lenalidomide-treated human myeloma cells inhibit angiogenesis in vitro
Hui-Mei Guo, Li Sun, Lin Yang, Xiao-Jun Liu, Zi-Yuan Nie, Jian-Min Luo
Pages: 2873-2880 Published online on: 23 April 2018
Article
Assessing stemness and proliferation properties of the newly established colon cancer ‘stem’ cell line, CSC480 and novel approaches to identify dormant cancer cells
Faisal Alowaidi, Saeed Mujahid Hashimi, Naif Alqurashi, Reem Alhulais, Saso Ivanovski, Bernadette Bellette, Adrian Meedenyia, Alfred Lam, Stephen Wood
Pages: 2881-2891 Published online on: 23 April 2018
Article
ERBB4 promotes the proliferation of gastric cancer cells via the PI3K/Akt signaling pathway
Ji Xu, Lijie Gong, Zhenyuan Qian, Guangyuan Song, Jinming Liu
Pages: 2892-2898 Published online on: 30 March 2018
Article
Cytochalasin H isolated from mangrove‑derived endophytic fungus induces apoptosis and inhibits migration in lung cancer cells
Yuefan Ma, Xin Wu, Zihan Xiu, Xin Liu, Bingyu Huang, Liang Hu, Jiao Liu, Zhiyuan Zhou, Xudong Tang
Pages: 2899-2905 Published online on: 30 March 2018
Article
miR-328-5p inhibits MDA-MB-231 breast cancer cell proliferation by targeting RAGE
Tingting Luo, Yueqiong Yan, Qiuxia He, Xiaoqian Ma, Wei Wang
Pages: 2906-2914 Published online on: 04 April 2018
Article
RIP2 promotes glioma cell growth by regulating TRAF3 and activating the NF‑κB and p38 signaling pathways
Xin Cai, Yongchang Yang, Wengrong Xia, Haibo Kong, Min Wang, Wenliang Fu, Minhui Long, Yuhua Hu, Donggang Xu
Pages: 2915-2923 Published online on: 23 April 2018
Article
Exogenous regucalcin suppresses the growth of human liver cancer HepG2 cells in vitro
Masayoshi Yamaguchi, Tomiyasu Murata
Pages: 2924-2930 Published online on: 05 April 2018
Article
The biological role of autophagy in regulating and controlling the proliferation of liver cancer cells induced by bufalin
Xia Sheng, Pengfei Zhu, Jianmin Qin, Qi Li
Pages: 2931-2941 Published online on: 12 April 2018
Article
Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the Akt‑GSK3β and MAPK/ERK signaling cascades
Xiaona Wang, Yanyan Zhu, Lili Zhu, Xinhuan Chen, Yanyan Xu, Yafei Zhao, Yingzhe Shao, Feng Li, Yanan Jiang, Jing Lu, Youtian Huang, Xiaobin Chang, Juan Zhang, Xiang Li, Kangdong Liu, Mingyao Zhao, Ziming Dong, Jimin Zhao
Pages: 2942-2950 Published online on: 23 April 2018
Article
PDK1 inhibitor GSK2334470 synergizes with proteasome inhibitor MG‑132 in multiple myeloma cells by inhibiting full AKT activity and increasing nuclear accumulation of the PTEN protein
Jin Zhang, Chunmei Yang, Fengping Zhou, Xiaohui Chen
Pages: 2951-2959 Published online on: 12 April 2018
Article
MicroRNA-616 promotes the progression of ovarian cancer by targeting TIMP2
Zhongbo Chen, Jianqing Zhu, Yiming Zhu, Junjian Wang
Pages: 2960-2968 Published online on: 12 April 2018
Article
Anticancer effect of exogenous hydrogen sulfide in cisplatin‑resistant A549/DDP cells
Ying Ma, Zhonghai Yan, Xiaomei Deng, Junqi Guo, Jinxia Hu, Yuan Yu, Fei Jiao
Pages: 2969-2977 Published online on: 12 April 2018
Article
HSPB8 promotes cancer cell growth by activating the ERK‑CREB pathway and is indicative of a poor prognosis in gastric cancer patients
Jian Shen, Minzhe Li, Li Min
Pages: 2978-2986 Published online on: 18 April 2018
Article
MicroRNA‑577 inhibits the migration and invasion of hepatocellular carcinoma cells by targeting homeobox A1
Shaoshan Han, Zhikui Liu, Yufeng Wang, Liang Wang, Bowen Yao, Cheng Guo, Tao Song, Kangsheng Tu, Qingguang Liu
Pages: 2987-2995 Published online on: 23 April 2018
Article
High expression of fructose-bisphosphate aldolase A induces progression of renal cell carcinoma
Zhengkai Huang, Yibo Hua, Ye Tian, Chao Qin, Jian Qian, Meiling Bao, Yiyang Liu, Shangqian Wang, Qiang Cao, Xiaobing Ju, Zengjun Wang, Min Gu
Pages: 2996-3006 Published online on: 18 April 2018
Article
Gallic acid sensitizes paclitaxel-resistant human ovarian carcinoma cells through an increase in reactive oxygen species and subsequent downregulation of ERK activation
Jessica Nayelli Sánchez-Carranza, J. Fernando Díaz, Mariano Redondo-Horcajo, Isabel Barasoain, Laura Alvarez, Pedro Lastres, Antonio Romero-Estrada, Patricio Aller, Leticia González-Maya
Pages: 3007-3014 Published online on: 18 April 2018
Article
miR-146a promotes cervical cancer cell viability via targeting IRAK1 and TRAF6
Qiming Hu, Jiacheng Song, Bo Ding, Yugui Cui, Jiale Liang, Suping Han
Pages: 3015-3024 Published online on: 23 April 2018
Article
Resveratrol decreases Rad51 expression and sensitizes cisplatin‑resistant MCF‑7 breast cancer cells
I. Leon‑Galicia, J. Diaz‑Chavez, M. E. Albino‑Sanchez, E. Garcia‑Villa, R. Bermudez‑Cruz, J. Garcia‑Mena, L. A. Herrera, A. García‑Carrancá, P. Gariglio
Pages: 3025-3033 Published online on: 27 March 2018
Article
GPNMB silencing suppresses the proliferation and metastasis of osteosarcoma cells by blocking the PI3K/Akt/mTOR signaling pathway
Rui Jin, Ying‑Ying Jin, Yi‑Lun Tang, Hua‑Juan Yang, Xiao‑Qian Zhou, Zhe Lei
Pages: 3034-3040 Published online on: 30 March 2018
Article
Doxycycline targets aldehyde dehydrogenase‑positive breast cancer stem cells
Chang‑Ching Lin, Miao‑Chia Lo, Rebecca R. Moody, Nicholas O. Stevers, Samantha L. Tinsley, Duxin Sun
Pages: 3041-3047 Published online on: 27 March 2018
Article
Lower endogenous p53 levels and degradation of AKT protein contribute to potent suppression of the new antibiotic Xiakemycin A on tumor cells
Chuan Chen, Zhongke Jiang, Xiuyuan Ou, Huixian Zhang, Chenghang Sun, Qiyang He
Pages: 3048-3054 Published online on: 18 April 2018
Article
Huaier suppresses proliferative and metastatic potential of prostate cancer PC3 cells via downregulation of Lamin B1 and induction of autophagy
Ailin Yang, Yanan Zhao, Ying Wang, Xiaojun Zha, Yunfang Zhao, Pengfei Tu, Zhongdong Hu
Pages: 3055-3063 Published online on: 05 April 2018
Article
Overexpression of IL-9 induced by STAT3 phosphorylation is mediated by miR-155 and miR-21 in chronic lymphocytic leukemia
Na Chen, Lili Feng, Huiting Qu, Kang Lu, Peipei Li, Xiao Lv, Xin Wang
Pages: 3064-3072 Published online on: 12 April 2018
Article
MicroRNA-33b-5p is overexpressed and inhibits GLUT4 by targeting HMGA2 in polycystic ovarian syndrome: An in vivo and in vitro study
Ying Yang, Hua Jiang, Ling Xiao, Xuezhou Yang
Pages: 3073-3085 Published online on: 18 April 2018
Article
