Journal Articles

Open Access

Precision medicine for human cancers with Notch signaling dysregulation (Review)

Masuko Katoh, Masaru Katoh

Pages: 279-297 Published online on: 04 December 2019
Open Access

Dormancy and NKG2D system in brain metastases: Analysis of immunogenicity

Charlotte Flüh, Victor Mafael, Vivian Adamski, Michael Synowitz, Janka Held‑Feindt

Pages: 298-314 Published online on: 30 December 2019
Open Access

Clinically relevant GSK‑3β inhibitor 9‑ING‑41 is active as a single agent and in combination with other antitumor therapies in human renal cancer

Tsutomu Anraku, Hiroo Kuroki, Akira Kazama, Vladimir Bilim, Masaaki Tasaki, Daniel Schmitt, Andrew Mazar, Francis J. Giles, Andrey Ugolkov, Yoshihiko Tomita

Pages: 315-323 Published online on: 12 December 2019
Open Access

CCR4‑NOT transcription complex subunit 2 regulates TRAIL sensitivity in non‑small‑cell lung cancer cells via the STAT3 pathway

Eun‑Ok Kim, Shi‑Eun Kang, Minji Choi, Ki‑Jong Rhee, Miyong Yun

Pages: 324-332 Published online on: 12 December 2019
Open Access

Construction of a long non‑coding RNA‑mediated transcription factor and gene regulatory triplet network reveals global patterns and biomarkers for ischemic stroke

Yuze Cao, Jianjian Wang, Xiaoyu Lu, Xiaotong Kong, Chunrui Bo, Shuang  Li, Jie Li, Xuesong Sun, Na Wang, Kuo Tian, Huixue Zhang, Liying Cui

Pages: 333-342 Published online on: 09 December 2019
Open Access

Andrographolide sodium bisulfate attenuates UV‑induced photo‑damage by activating the keap1/Nrf2 pathway and downregulating the NF‑κB pathway in HaCaT keratinocytes

Mei‑Ling Wang, Qing‑Yuan Zhong, Bao‑Qin Lin, Yu‑Hong Liu, Yan‑Feng Huang, Yang Chen, Jie Yuan, Zi‑Ren Su, Janis Ya‑Xian Zhan

Pages: 343-352 Published online on: 02 December 2019
Open Access

A novel small molecule compound VCP979 improves ventricular remodeling in murine models of myocardial ischemia/reperfusion injury

Jing Liu, Qingshu Meng, Xiaoting Liang, Rulin Zhuang, Dongsheng Yuan, Xinyu Ge, Hao Cao, Fang Lin, Xin Gong, Huimin Fan, Binghui Wang, Xiaohui Zhou, Zhongmin Liu

Pages: 353-364 Published online on: 27 November 2019
Open Access

Prenatal ethanol exposure enhances the susceptibility to depressive behavior of adult offspring rats fed a high‑fat diet by affecting BDNF‑associated pathway

Ying Yu, Dan Xu, Siyuan Cheng, Li Zhang, Zhaokun Shi, Jun Qin, Zhaohui Zhang, Hui Wang

Pages: 365-374 Published online on: 19 December 2019
Open Access

Overexpression of miR‑30c‑5p reduces cellular cytotoxicity and inhibits the formation of kidney stones through ATG5

Xin Wang, Yanan Zhang, Shuai Han, Hongshen Chen, Chen Chen, Lingling Ji, Bihu Gao

Pages: 375-384 Published online on: 23 December 2019
Open Access

The role of myoglobin in epithelial cancers: Insights from transcriptomics

Anne Bicker, Theresa Nauth, Daniela Gerst, Mostafa Ahmed Aboouf, Joachim Fandrey, Glen Kristiansen, Thomas Alexander Gorr, Thomas Hankeln

Pages: 385-400 Published online on: 18 December 2019
Open Access

Weighted gene co‑expression network analysis to identify key modules and hub genes associated with atrial fibrillation

Wenyuan Li, Lijun Wang, Yue Wu, Zuyi Yuan, Juan Zhou

Pages: 401-416 Published online on: 03 December 2019
Open Access

Humulus japonicus extract ameliorates collagen‑induced arthritis in mice through regulation of overall articular inflammation

Eun‑Jung Kang, Hyun Jong Kim, Ji Hyun Choi, Jung‑Ran Noh, Jae‑Hoon Kim, In Bok Lee, Young‑Keun Choi, Dong‑Hee Choi, Jinpyo An, Won Keun Oh, Yong‑Hoon Kim, Chul‑Ho Lee

Pages: 417-428 Published online on: 03 December 2019
Open Access

Inhibition of miR‑155‑5p attenuates the valvular damage induced by rheumatic heart disease

Ang Chen, Jianlin Wen, Chuanghong Lu, Beiyou Lin, Shenglin Xian, Feng Huang, Yunjiao Wu, Zhiyu Zeng

Pages: 429-440 Published online on: 06 December 2019
Open Access

miRNA‑384‑5p regulates the progression of Parkinson's disease by targeting SIRT1 in mice and SH‑SY5Y cell

Hongli Tao, Yan Liu, Yingjuan Hou

Pages: 441-450 Published online on: 12 December 2019
Open Access

Circular RNA_101237 mediates anoxia/reoxygenation injury by targeting let‑7a‑5p/IGF2BP3 in cardiomyocytes

Jianting Gan, Jun Yuan, Yu Liu, Zhengde Lu, Yan Xue, Lei Shi, Huayuan Zeng

Pages: 451-460 Published online on: 23 December 2019
Open Access

MicroRNA‑15a‑5p induces pulmonary artery smooth muscle cell apoptosis in a pulmonary arterial hypertension model via the VEGF/p38/MMP‑2 signaling pathway

Wenmei Zhang, Yanna Li, Xin Xi, Guangfa Zhu, Shenghao Wang, Yan Liu, Man Song

Pages: 461-474 Published online on: 18 December 2019
Open Access

CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus

Qiong Wu, Miao Zhang, Xueyan Liu, Junmei Zhang, Hua Wang

Pages: 475-484 Published online on: 23 December 2019
Open Access

Cancer‑related fatigue during combined treatment of androgen deprivation therapy and radiotherapy is associated with mitochondrial dysfunction Corrigendum in /10.3892/ijmm.2020.4546

Li Rebekah Feng, Brian S. Wolff, Josephine Liwang, Jeniece M. Regan, Sarah Alshawi, Sumiyya Raheem, Leorey N. Saligan

Pages: 485-496 Published online on: 18 December 2019
Open Access

lncRNA CYTOR promotes tamoxifen resistance in breast cancer cells via sponging miR‑125a‑5p

Yungyong Liu, Mengdan Li, Huihui Yu, Haozhe Piao

Pages: 497-509 Published online on: 16 December 2019
Open Access

miR‑195 promotes LPS‑mediated intestinal epithelial cell apoptosis via targeting SIRT1/eIF2a

Ting Yuan, Li Zhang, Shuo Yao, Shuang‑Ya Deng, Ji‑Qiang Liu

Pages: 510-518 Published online on: 18 December 2019
Open Access

Combination of the ginsenosides Rb3 and Rb2 exerts protective effects against myocardial ischemia reperfusion injury in rats

Xiaomin Liu, Yichuan Jiang, Wenwen Fu, Xiaofeng Yu, Dayun Sui

Pages: 519-531 Published online on: 29 November 2019
Open Access

Upregulation of miR‑423 improves autologous vein graft restenosis via targeting ADAMTS‑7

Wenjun Ren, Liwen Liang, Yongwu Li, Fei‑Yu Wei, Ninghui Mu, Libin Zhang, Wei He, Yu Cao, Da Xiong, Hongrong Li

Pages: 532-542 Published online on: 05 December 2019
Open Access

miR‑146a improves hepatic lipid and glucose metabolism by targeting MED1

Kun Li, Bao Zhao, Diandian Wei, Wenrui Wang, Yixuan Cui, Lisheng Qian, Guodong Liu

Pages: 543-555 Published online on: 27 December 2019
Open Access

Protective effects of human umbilical cord blood‑derived mesenchymal stem cells against dexamethasone‑induced apoptotic cell death in hair follicles

Dong Ho Bak, Esther Lee, Mi Ji Choi, Byung Chul Lee, Tae‑Rin Kwon, Jong‑Hwan Kim, Eun Su Jeon, Wonil Oh, Seog Kyun Mun, Byung Cheol Park, Jungtae Na, Beom Joon Kim

Pages: 556-568 Published online on: 27 December 2019
Open Access

miR‑139‑5p affects cell proliferation, migration and adipogenesis by targeting insulin‑like growth factor 1 receptor in hemangioma stem cells

Yao Wu, Honghong Li, Juan Xie, Fan Wang, Dongsheng Cao, Yin Lou

Pages: 569-577 Published online on: 17 December 2019
Open Access

lncRNA BCAR4 sponges miR‑370‑3p to promote bladder cancer progression via Wnt signaling

Rongkui Zhang, Jiping Wang, Er'na Jia, Jialiang Zhang, Nan Liu, Changliang Chi

Pages: 578-588 Published online on: 27 December 2019

Acer okamotoanum inhibits adipocyte differentiation by the regulation of adipogenesis and lipolysis in 3T3‑L1 cells

Ji Hyun Kim, Sanghyun Lee, Hyun Young Kim, Eun Ju Cho

Pages: 589-596 Published online on: 30 December 2019

MicroRNA‑432 inhibits the aggressiveness of glioblastoma multiforme by directly targeting IGF‑1R

Xudong Chen, Xufei Zhang, Shunjin Sun, Meixiao Zhu

Pages: 597-606 Published online on: 16 December 2019

Histone H3K9 methylation is involved in temporomandibular joint osteoarthritis

Mayumi Ukita, Kenji Matsushita, Masato Tamura, Taihiko Yamaguchi

Pages: 607-614 Published online on: 27 December 2019

NOS cofactor tetrahydrobiopterin contributes to anesthetic preconditioning induced myocardial protection in the isolated ex vivo rat heart

Chen Wang, Shigang Qiao, Lei Hong, Jie Sun, Tuanjie Che, Jianzhong An, Amadou K.S. Camara

Pages: 615-622 Published online on: 27 December 2019

Metformin alleviates endometrial hyperplasia through the UCA1/miR‑144/TGF‑β1/AKT signaling pathway

Miao Guo, Jing‑Jing Zhou, Wei Huang

Pages: 623-633 Published online on: 23 December 2019

Deficiency of Pdk1 contributes to primordial follicle activation via the upregulation of YAP expression and the pro‑inflammatory response

Jiayin Gao, Tiefang Song, Dehong Che, Changmin Li, Jing Jiang, Jingyao Pang, Yujuan Yang, Peiling Li

Pages: 647-657 Published online on: 20 December 2019

Anti‑platelet activity of mineral‑balanced deep sea water is mediated via the regulation of Akt and ERK pathway crosstalk

Gi Suk Nam, Kyu‑Shik Lee, Kyung‑Soo Nam

Pages: 658-668 Published online on: 10 December 2019

Upregulation of AGR2vH facilitates cholangiocarcinoma cell survival under endoplasmic reticulum stress via the activation of the unfolded protein response pathway

Gunticha Suwanmanee, Juthamas Yosudjai, Suchada Phimsen, Sopit Wongkham, Siwanon Jirawatnotai, Worasak Kaewkong

Pages: 669-677 Published online on: 18 December 2019

Preconditioning with repetitive electromagnetic stimulation enhances activity of bone marrow mesenchymal stem cells from elderly patients through Erk1/2 via nitric oxide

Seungwoo Nam, Suna Kim, Kangjun Yoon, Hyun Sook Hong, Youngsook Son

Pages: 678-686 Published online on: 30 December 2019
Open Access

[Corrigendum] Nobiletin, a citrus flavonoid, activates vasodilator-stimulated phosphoprotein in human platelets through non‑cyclic nucleotide‑related mechanisms

Thanasekaran Jayakumar, Kao-Chang Lin, Wan-Jung Lu, Chia-Ying Lin, Geraldine Pitchairaj, Jiun-Yi Li, Joen-Rong Sheu

Pages: 687-687 Published online on: 10 December 2019
Open Access

[Corrigendum] Structure‑activity relationship of three synthesized benzimidazole‑based oligosaccharides in human platelet activation

Yi Chang, Wen-Hsien Hsu, Wen-Bin Yang, Thanasekaran Jayakumar, Tzu-Yin Lee, Joen-Rong Sheu, Wan-Jung Lu, Jiun-Yi Li

Pages: 688-688 Published online on: 10 December 2019
Journal Cover

February-2020
Volume 45 Issue 2

Print ISSN: 1107-3756
Online ISSN: 1791-244X

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