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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2014 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Significant role of macrophages in human cancers associated with Epstein-Barr virus (Review)

Misuzu Shimakage
Pages: 1763-1771
Published online on: 10 September 2014

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Article Open Access

Detection and preliminary evaluation of circulating tumor cells in the peripheral blood of patients with eight types of cancer using a telomerase-specific adenovirus

Mina Yabusaki, Jun Sato, Atsushi Kohyama, Takashi Kojima, Daisuke Nobuoka, Toshiaki Yoshikawa, Yu Sawada, Katsuhiro  Murakami, Keigo  Gohda, Takatsugu Okegawa, Masaru Nakamura, Kiyoshi  Takamatsu, Masaaki Ito, Kazuhiro Kaneko, Tetsuya Nakatsura
Pages: 1772-1778
Published online on: 22 August 2014

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Article Open Access

Suppression of PMA-induced tumor cell invasion and migration by ginsenoside Rg1 via the inhibition of NF-κB-dependent MMP-9 expression

Li Li, Yiwen Wang, Benquan Qi, Dongdong Yuan, Shuying Dong, Daohua Guo, Cuiling Zhang, Meiling Yu
Pages: 1779-1786
Published online on: 20 August 2014

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Article Open Access

Targeting of the β6 gene to suppress degradation of ECM via inactivation of the MAPK pathway in breast adenocarcinoma cells

Yuhua Zhang, Lijing Wei, Jin Yu, Guang Li, Xiuru Zhang, Anliu Wang, Yanjiao He, Hongli Li, Deling Yin
Pages: 1787-1795
Published online on: 20 August 2014

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Article

Interaction of Muc4 and ErbB2 in a transgenic mouse model of gallbladder carcinoma: Potential pathobiological implications

Naoki Miyahara, Junichi Shoda, Toru  Kawamoto, Hiroyasu  Ishida, Tetsuya  Ueda, Yoshihiro  Akimoto, Hayato  Kawakami, Tatsuro Irimura
Pages: 1796-1802
Published online on: 25 August 2014

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Article

Synergistic antitumor effect of ginsenoside Rg3 and cisplatin in cisplatin‑resistant bladder tumor cell line

Young Ju Lee, Sangchul Lee, Jin Nyoung Ho, Seok-Soo Byun, Sung Kyu Hong, Sang Eun Lee, Eunsik  Lee
Pages: 1803-1808
Published online on: 29 August 2014

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Article

A novel RET rearrangement (ACBD5/RET) by pericentric inversion, inv(10)(p12.1;q11.2), in papillary thyroid cancer from an atomic bomb survivor exposed to high-dose radiation

Kiyohiro Hamatani, Hidetaka Eguchi, Kazuaki  Koyama, Mayumi  Mukai, Kei Nakachi, Yoichiro Kusunoki
Pages: 1809-1814
Published online on: 29 August 2014

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Article

Usefulness of immunohistochemistry for the detection of the BRAF V600E mutation in ovarian serous borderline tumors

Yuko Hayashi, Hidefumi Sasaki, Sho Takeshita, Ryutaro Nishikawa, Hiroshi Nishikawa, Atsushi Arakawa, Yoriko Yamashita, Satoru Takahashi, Mayumi Sugiura-Ogasawara
Pages: 1815-1819
Published online on: 25 August 2014

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Article

Carbon ions and X‑rays induce pro‑inflammatory effects in 3D oral mucosa models with and without PBMCs

Viktoria Tschachojan, Henrike Schroer, Nicole Averbeck, Wolfgang Mueller-Klieser
Pages: 1820-1828
Published online on: 22 August 2014

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Article

CMTM1_v17 is a novel potential therapeutic target in breast cancer

Jing Wang, Guoying Zhang, Yingmei Zhang, Yang Luo, Quansheng Song, Xiaoyan Qiu, Xiaoning Mo, Lu Wang
Pages: 1829-1836
Published online on: 20 August 2014

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Article

MyD88 expression is associated with paclitaxel resistance in lung cancer A549 cells

Fenfen Xiang, Rong Wu, Zhenhua  Ni, Chunying  Pan, Yueping Zhan, Jian  Xu, Xianpeng  Meng, Xiangdong Kang
Pages: 1837-1844
Published online on: 21 August 2014

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Article

Identification of copy number variation-driven genes for liver cancer via bioinformatics analysis

Xiaojie Lu, Kun Ye, Kailin Zou, Jinlian Chen
Pages: 1845-1852
Published online on: 20 August 2014

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Article

Hiwi facilitates chemoresistance as a cancer stem cell marker in cervical cancer

Wei Liu, Qing Gao, Kunlun Chen, Xiang Xue, Mu Li, Qian Chen, Gaixia Zhu, Ya Gao
Pages: 1853-1860
Published online on: 13 August 2014

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Article

BMP8B mediates the survival of pancreatic cancer cells and regulates the progression of pancreatic cancer

Zhuoxin Cheng, Wu Cui, Ye Ding, Tao Liu, Weixin  Liu, Youyou  Qin, Weibin  Xia, Jian  Xu, Yinghai  Zhang, Xiaoming Zou
Pages: 1861-1866
Published online on: 18 August 2014

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Article

The role of APOBEC3B in chondrosarcoma

Zhe Jin, Ya-Xin Han, Xiao-Rui Han
Pages: 1867-1872
Published online on: 22 August 2014

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Article

Activation of the mTORC1 and STAT3 pathways promotes the malignant transformation of colitis in mice

Zhen He, Xiaosheng He, Zexian Chen, Jia Ke, Xiaowen He, Ruixue Yuan, Zerong Cai, Xiuting Chen, Xiaojian Wu, Ping Lan
Pages: 1873-1880
Published online on: 20 August 2014

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Article

Apoptosis- and differentiation-inducing activities of jacaric acid, a conjugated linolenic acid isomer, on human eosinophilic leukemia EoL-1 cells

Wai‑Nam Liu, Kwok‑Nam Leung
Pages: 1881-1888
Published online on: 26 August 2014

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Article

Fluorescence in situ hybridization of chromosome 17 polysomy in breast cancer using thin tissue sections causes the loss of CEP17 and HER2 signals

Huiyong Jiang, Xiaoyan Bai, Tong Zhao, Cheng Zhang, Xuefeng Zhang
Pages: 1889-1896
Published online on: 13 August 2014

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Article

Overexpression of type VI collagen in neoplastic lung tissues

Larry Voiles, David E. Lewis, Ling Han, Ivan P. Lupov, Tsang-Long Lin, Michael J. Robertson, Irina Petrache, Hua-Chen Chang
Pages: 1897-1904
Published online on: 22 August 2014

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Article

Inhibition of autophagy enhances the radiosensitivity of nasopharyngeal carcinoma by reducing Rad51 expression

Ning Mo, Yong-Kui Lu, Wei-Min Xie, Yan Liu, Wen-Xian Zhou, Hong-Xue Wang, Li Nong, Yu-Xian Jia, Ai-Hua Tan, Ying Chen, Shan-Shan Li, Bao-Hua Luo
Pages: 1905-1912
Published online on: 20 August 2014

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Article

Knockout of ADAM10 enhances sorafenib antitumor activity of hepatocellular carcinoma in vitro and in vivo

Wei Zhang, Songyang Liu, Kai Liu, Bai  Ji, Yingchao Wang, Yahui Liu
Pages: 1913-1922
Published online on: 19 August 2014

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Article

MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma

Yuwu Liu, Chang Wu, Ying Wang, Sailan Wen, Junpu Wang, Zhihong Chen, Qiongqiong He, Deyun Feng
Pages: 1923-1930
Published online on: 20 August 2014

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Article

Reduced expression of liver kinase B1 and Beclin1 is associated with the poor survival of patients with non-small cell lung cancer

Lili Jiang, Xuan Liang, Mengjie Liu, Wenjuan Wang, Jiequn Ma, Qianqian Guo, Lili Han, Chengcheng Yang, Kejun Nan
Pages: 1931-1938
Published online on: 21 August 2014

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Article

Overexpression of oxidored-nitro domain containing protein 1 induces growth inhibition and apoptosis in human prostate cancer PC3 cells

Zhongjie Shan, Qinglan Hou, Nan Zhang, Liang Guo, Xinheng Zhang, Yaohui Ma, Yudong Zhou
Pages: 1939-1946
Published online on: 14 August 2014

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Article

Downregulated Chibby in laryngeal squamous cell carcinoma with increased expression in laryngeal carcinoma Hep-2 cells

Jue Xu, Gang Ren, De-An Zhao, Bo-An Li, Cheng-Fu Cai, Yi Zhou, Xian-Yang Luo
Pages: 1947-1956
Published online on: 29 August 2014

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Article

Immune responsive gene 1, a novel oncogene, increases the growth and tumorigenicity of glioma

Jun Pan, Xiaoyong Zhao, Chunnan Lin, Hongchao Xu, Zhilin Yin, Tianzhu Liu, Shizhong Zhang
Pages: 1957-1966
Published online on: 10 September 2014

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Article

Nuclear ING2 expression is reduced in osteosarcoma

Xiao-Rui Han, Xi-Zhuang Bai, Yu Sun, Yan Yang
Pages: 1967-1972
Published online on: 02 September 2014

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Article

Mammalian target of rapamycin signaling is involved in the vasculogenic mimicry of glioma via hypoxia-inducible factor-1α

Min Huang, Yiquan Ke, Xinlin Sun, Li Yu, Zhilin Yang, Yonghong Zhang, Mouxuan Du, Jihui Wang, Xiao Liu, Shuyun Huang
Pages: 1973-1980
Published online on: 29 August 2014

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Article

Microarray-based detection and expression analysis of extracellular matrix proteins in drug‑resistant ovarian cancer cell lines

Radosław Januchowski, Piotr Zawierucha, Marcin  Ruciński, Maciej Zabel
Pages: 1981-1990
Published online on: 09 September 2014

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Article

AZD1480, a JAK inhibitor, inhibits cell growth and survival of colorectal cancer via modulating the JAK2/STAT3 signaling pathway

Shu-Wei Wang, Jun Hu, Qin-Hao Guo, Yan Zhao, Jie-Jing Cheng, Dong‑Sheng Zhang, Qiang Fei, Juan Li, Yue-Ming Sun
Pages: 1991-1998
Published online on: 10 September 2014

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Article

XAV939 promotes apoptosis in a neuroblastoma cell line via telomere shortening

Xiaohong Tian, Weijian Hou, Shuling Bai, Jun  Fan, Hao Tong, Yu Bai
Pages: 1999-2006
Published online on: 02 September 2014

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Article

Circulating endothelial progenitor cells are involved in VEGFR-2-related endothelial differentiation in glioma

Le Wang, Lu Chen, Qianfeng Wang, Lijuan Wang, Haibao Wang, Yujun Shen, Xiaohu Li, Yu Fu, Yuxian Shen, Yongqiang Yu
Pages: 2007-2014
Published online on: 05 September 2014

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Article

Reversion of trichostatin A resistance via inhibition of the Wnt signaling pathway in human pancreatic cancer cells

Benquan Wang, Qian Zou, Meng Sun, Jingfeng Chen, Tianyang Wang, Yongheng Bai, Zongjing Chen, Bicheng Chen, Mengtao Zhou
Pages: 2015-2022
Published online on: 10 September 2014

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Article

Knockdown of mutated H-Ras V12 expression induces chemosensitivity of hepatocellular carcinoma cells to cisplatin treatment in vitro and in nude mouse xenografts

Fanjie Meng, Bin Cao, Zengli Feng, Shunmao Ma, Haigang Wang, Yanshu Li, Hui Li
Pages: 2023-2030
Published online on: 05 September 2014

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Article

Role of aldolase A in osteosarcoma progression and metastasis: In vitro and in vivo evidence

Feng Long, Xinyan Cai, Wei Luo, Liang Chen, Kanghua Li
Pages: 2031-2037
Published online on: 10 September 2014

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Article

Downregulation of STAT3 and activation of MAPK are involved in the induction of apoptosis by HNK in glioblastoma cell line U87

Yubao Zhang, Xia Ren, Meiyan Shi, Zheng  Jiang, Hengxiao  Wang, Qinghong Su, Qinglin Liu, Gang Li, Guosheng Jiang
Pages: 2038-2046
Published online on: 22 August 2014

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Article

CUL4B promotes proliferation and inhibits apoptosis of human osteosarcoma cells

Zhi Chen, Bao-Liang Shen, Qing-Ge Fu, Fei Wang, Yi‑Xing Tang, Cang-Long Hou, Li Chen
Pages: 2047-2053
Published online on: 05 September 2014

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Article

Evolution of a gastric carcinoma cell-specific DNA aptamer by live cell-SELEX

Hong-Yong Cao, Ai-Hua Yuan, Xue-Song Shi, Wei  Chen, Yi Miao
Pages: 2054-2060
Published online on: 18 August 2014

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Article

Identification of angiogenesis-related miRNAs in a population of patients with renal clear cell carcinoma

He-Cheng Li, Jian-Ping Li, Zi-Ming  Wang, De-Lai  Fu, Zhao‑Lun  Li, Dong  Zhang, Wei-Min  Gan, Tie  Chong
Pages: 2061-2069
Published online on: 14 August 2014

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Article

Upregulation of Limk1 caused by microRNA-138 loss aggravates the metastasis of ovarian cancer by activation of Limk1/cofilin signaling

Puxiang Chen, Mengjun Zeng, Yan Zhao, Xiaolin Fang
Pages: 2070-2076
Published online on: 02 September 2014

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Article

Expression of GOLPH2 is associated with the progression of and poor prognosis in gastric cancer

Guanglin Liu, Yan Zhang, Fen He, Jianfeng Li, Xuan Wei, Yang Li, Xiaowen Liao, Jiancong Sun, Wei Yi, Daoli Niu
Pages: 2077-2085
Published online on: 14 August 2014

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Article

Aberrant expression of B7-H3 in gastric adenocarcinoma promotes cancer cell metastasis Retraction in /10.3892/or.2022.8421

Wei Dai, Genhai Shen, Jianping Qiu, Xin Zhao, Quangen Gao
Pages: 2086-2092
Published online on: 14 August 2014

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Article

DNA methyltransferases 3a and 3b are differentially expressed in the early stages of a rat liver carcinogenesis model

Carlos Alberto Valencia Antúnez, Lucía Taja Chayeb, Miguel Ángel Rodríguez-Segura, Guadalupe Soledad López Álvarez, Claudia M. García-Cuéllar, Saúl Villa Treviño
Pages: 2093-2103
Published online on: 03 September 2014

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Article

miR-124a restoration inhibits glioma cell proliferation and invasion by suppressing IQGAP1 and β-catenin

Shao-Hua Lu, Xing-Jun Jiang, Ge-Lei Xiao, Ding-Yang Liu, Xian-Rui Yuan
Pages: 2104-2110
Published online on: 29 August 2014

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Article

The endogenous oxindole isatin induces apoptosis of MCF‑7 breast cancer cells through a mitochondrial pathway

Zhongliang Ma, Lin Hou, Yuhong Jiang, Yanpin Chen, Jinlian Song
Pages: 2111-2117
Published online on: 20 August 2014

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Article

Matrine alters microRNA expression profiles in SGC-7901 human gastric cancer cells

Hailong Li, Shoupin Xie, Xiaojun Liu, Hongyan Wu, Xinyao Lin, Jing Gu, Huping Wang, Yongqiang Duan
Pages: 2118-2126
Published online on: 28 August 2014

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Article

MicroRNA-497 suppresses angiogenesis by targeting vascular endothelial growth factor A through the PI3K/AKT and MAPK/ERK pathways in ovarian cancer

Wei Wang, Fang Ren, Qinghua Wu, Dazhi Jiang, Hongjun Li, Huirong Shi
Pages: 2127-2133
Published online on: 22 August 2014

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Article

Transforming growth factor-β1-induced epithelial-mesenchymal transition in human esophageal squamous cell carcinoma via the PTEN/PI3K signaling pathway

Hong-Yan Zhang, Zhi-Qiang Wang, Yun-Yun Li, Feng Wang, Qing-Ru Zeng, Yuan Gao, Xiao-Yan Xuan, Shan-Shan Li
Pages: 2134-2142
Published online on: 29 August 2014

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Article

MicroRNA-101 inhibits the metastasis of osteosarcoma cells by downregulation of EZH2 expression

Kailiang Zhang, Yinglong Zhang, Kun Ren, Guangyi Zhao, Kang Yan, Baoan Ma
Pages: 2143-2149
Published online on: 02 September 2014

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Article

Reactive oxygen species promote ovarian cancer progression via the HIF-1α/LOX/E-cadherin pathway

Yu Wang, Jun Ma, Haoran Shen, Chengjie  Wang, Yueping  Sun, Stephen B. Howell, Xinjian Lin
Pages: 2150-2158
Published online on: 28 August 2014

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Article

PEG10 plays a crucial role in human lung cancer proliferation, progression, prognosis and metastasis

Xinzhou Deng, Yi Hu, Qianshan Ding, Rongfei Han, Qian Guo, Jian Qin, Jie Li, Ruijing Xiao, Sufang Tian, Weidong Hu, Qiuping Zhang, Jie Xiong
Pages: 2159-2167
Published online on: 09 September 2014

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Article

ABCG2 regulates the pattern of self-renewing divisions in cisplatin-resistant non-small cell lung cancer cell lines

Ying Tang, Jingming Hou, Guanghui Li, Zongchang Song, Xiaojing Li, Cui Yang, Wenying Liu, Yide Hu, Yu Xu
Pages: 2168-2174
Published online on: 09 September 2014

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Article

Erk1/2 activation and modulation of STAT3 signaling in oral cancer

Ioannis Gkouveris, Nikolaos Nikitakis, Maria Karanikou, George Rassidakis, Alexandra Sklavounou
Pages: 2175-2182
Published online on: 22 August 2014

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Article

Upregulation of GRIM-19 suppresses the growth of oral squamous cell carcinoma in vitro and in vivo Retraction in /10.3892/or.2025.8955

Minghe Li, Zhihong Li, Chongyang Liang, Chengmin Han, Wei Huang, Fei Sun
Pages: 2183-2190
Published online on: 20 August 2014

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Article

Association of increased levels of TGF-β1 and p14ARF in prostate carcinoma cell lines overexpressing Egr-1

Eduardo Parra, Luis Gutiérrez, Jorge Ferreira
Pages: 2191-2198
Published online on: 09 September 2014

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Article

hMSH2 expression is associated with paclitaxel resistance in ovarian carcinoma, and inhibition of hMSH2 expression in vitro restores paclitaxel sensitivity

Jin Zhang, Dongmei Yin, Hongxia Li
Pages: 2199-2206
Published online on: 20 August 2014

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Article

EPO gene expression induces the proliferation, migration and invasion of bladder cancer cells through the p21WAF1‑mediated ERK1/2/NF-κB/MMP-9 pathway

Sung Lyea Park, Se Yeon Won, Jun-Hui Song, Wun-Jae Kim, Sung-Kwon Moon
Pages: 2207-2214
Published online on: 20 August 2014

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Article

Chitooligosaccharides inhibit ethanol-induced oxidative stress via activation of Nrf2 and reduction of MAPK phosphorylation

Zhiguo Luo, Xiaoxia Dong, Qing Ke, Qiwen  Duan, Li Shen
Pages: 2215-2222
Published online on: 03 September 2014

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Article

Epidermal growth factor receptor and KRAS mutations in lung adenocarcinoma: A retrospective study of the Lebanese population

Najla Fakhruddin, Rami Mahfouz, Fadi Farhat, Arafat Tfayli, Rabab Abdelkhalik, Mark Jabbour, Lamis Yehia, Ziyad Mahfoud, Ghazi Zaatari
Pages: 2223-2229
Published online on: 14 August 2014

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Article

Induction of fibronectin in response to epidermal growth factor is suppressed by silibinin through the inhibition of STAT3 in triple negative breast cancer cells

Sangmin Kim, Myeongjin Jeon, Jeongmin Lee, Jeonghun Han, Soo‑Jin  Oh, Taewoo Jung, Seok Jin Nam, Won Ho Kil, Jeong Eon Lee
Pages: 2230-2236
Published online on: 29 August 2014

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Volumetric intensity modulated arc therapy for stereotactic body radiosurgery in oligometastatic breast and gynecological cancers: Feasibility and clinical results

Gabriella Macchia, Francesco Deodato, Savino Cilla, Gabriella Torre, Giacomo Corrado, Francesco Legge, Maria Antonietta Gambacorta, Luca Tagliaferri, Samantha Mignogna, Giovanni Scambia, Vincenzo Valentini, Alessio G. Morganti, Gabriella Ferrandina
Pages: 2237-2243
Published online on: 18 August 2014

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Phenotypic and functional characterization of cytokine-induced killer cells derived from preterm and term infant cord blood

Qian Zhang, Lili Wang, Chenghan Luo, Zanyang  Shi, Xinru Cheng, Zhen Zhang, Yi Yang, Yi Zhang
Pages: 2244-2252
Published online on: 01 September 2014

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SHIP1 is targeted by miR-155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Pages: 2253-2259
Published online on: 22 August 2014

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C5a promotes the proliferation of human nasopharyngeal carcinoma cells through PCAF-mediated STAT3 acetylation

Kemin Cai, Yi Wan, Zhimin Wang, Yu Wang, Xiaojun Zhao, Xueli Bao
Pages: 2260-2266
Published online on: 20 August 2014

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Intratumoral injection of PKR shRNA expressing plasmid inhibits B16-F10 melanoma growth Corrigendum in /10.3892/or.2018.6646

Nayara Delgado André, Viviane Aline Oliveira Silva, Maria Angelica Ehara Watanabe, Fernando Luiz De Lucca
Pages: 2267-2273
Published online on: 18 August 2014

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Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell line

Hui Ling, Li-Feng Lu, Jie He, Guo-Hua  Xiao, Hao Jiang, Qi Su
Pages: 2274-2282
Published online on: 19 August 2014

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Article

miR-21 increases the programmed cell death 4 gene-regulated cell proliferation in head and neck squamous carcinoma cell lines

Zhifeng Sun, Suping Li, Andreas M. Kaufmann, Andreas E. Albers
Pages: 2283-2289
Published online on: 01 September 2014

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Journal Cover
January-2026 Volume 55 Issue 1

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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