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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2014 Volume 10 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Inflammatory response in Parkinson's disease (Review)

Junqiang Yan, Qizhi Fu, Liniu Cheng, Mingming Zhai, Wenjuan Wu, Lina Huang, Ganqin Du
Pages: 2223-2233
Published online on: 12 September 2014

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Review

ER stress in adipocytes and insulin resistance: Mechanisms and significance (Review)

Shahzad Khan, Chang Hua Wang
Pages: 2234-2240
Published online on: 03 September 2014

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Review

Research progress on the central mechanism underlying regulation of visceral biological rhythm by per2 (Review)

Liting Zhu, Jun Yu, Wenyi Zhang, Bin Xie, Yi Zhu
Pages: 2241-2248
Published online on: 11 September 2014

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Article Open Access

Effects of lentiviral infection of mesenchymal stem cells on the expression of octamer transcription factor 4

Jing Chang, Li Tang, Han Lei, Xiao-Gang Zhang, Zhong Zuo, Wei Huang, Hang Fu
Pages: 2249-2254
Published online on: 21 August 2014

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Article Open Access

Taurine supplementation reduces oxidative stress and protects the liver in an iron-overload murine model

Zeyu Zhang, Dan Liu, Bo Yi, Zhangping Liao, Lei Tang, Dong Yin, Ming He
Pages: 2255-2262
Published online on: 05 September 2014

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Article Open Access

Alterations in the expression of vascular endothelial growth factor in the rat brain following gamma knife surgery

Lei Cheng, Lin Ma, Hecheng Ren, Hongwei Zhao, Yiqiang  Pang, Yongheng Wang, Ming Wei
Pages: 2263-2270
Published online on: 27 August 2014

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Article Open Access

1‑calcium phosphate‑uracil, a synthesized pyrimidine derivative agent, has anti‑proliferative, pro‑apoptotic and anti‑invasion effects on multiple tumor cell lines

Jing Peng, Xinlian Chen, Qian Hu, Mei Yang, Hongqian  Liu, Wei Wei, Shanling Liu, He Wang
Pages: 2271-2278
Published online on: 14 August 2014

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Article Open Access

Death receptor 5 expression IS inversely correlated WITH prostate cancer progression Corrigendum in /10.3892/mco.2017.7234

Angeles Hernandez‑Cueto, Daniel Hernandez‑Cueto, Gabriela Antonio‑Andres, Marisela Mendoza‑Marin, Carlos Jimenez‑Gutierrez, Ana Lilia Sandoval‑Mejia, Rosario Mora‑Campos, Cesar Gonzalez‑Bonilla, Mario I. Vega, Benjamin Bonavida, Sara Huerta‑Yepez
Pages: 2279-2286
Published online on: 21 August 2014

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Article Open Access

Milk thistle seed extract protects rat C6 astroglial cells from acute cocaine toxicity

Ramesh B. Badisa, Cheryl A. Fitch-Pye, Maryam Agharahimi, Donald E. Palm, Lekan M. Latinwo, Carl B. Goodman
Pages: 2287-2292
Published online on: 28 August 2014

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Article Open Access

Secreted frizzled‑related protein 2 is epigenetically silenced and functions as a tumor suppressor in oral squamous cell carcinoma

Can Xiao, Lili Wang, Lifang Zhu, Chenping Zhang, Jianhua Zhou
Pages: 2293-2298
Published online on: 05 September 2014

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Article Open Access

Effect of bone marrow stromal cell transplantation on neurologic function and expression of VEGF in rats with focal cerebral ischemia

Nan Li, Ping Wang, Xue-Ling Ma, Juan Wang, Li-Jing Zhao, Li Du, Li-Ya Wang, Xin-Rui Wang, Kang-Ding Liu
Pages: 2299-2305
Published online on: 20 August 2014

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Article Open Access

Critical role of insulin‑like growth factor binding protein‑5 in methamphetamine‑induced apoptosis in cardiomyocytes

Ka‑Pui Leung, Yi‑Hong Qu, Dong‑Fang Qiao, Wei‑Bing Xie, Dong‑Ri Li, Jing‑Tao Xu, Hui‑Jun Wang, Xia  Yue
Pages: 2306-2312
Published online on: 16 September 2014

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Article Open Access

Upregulation of heat shock factor 1 transcription activity is associated with hepatocellular carcinoma progression

Shulian Li, Wanli Ma, Teng Fei, Qiang Lou, Yaqin Zhang, Xiukun  Cui, Xiaoming Qin, Jun  Zhang, Guangchao Liu, Zheng Dong, Yuanfang Ma, Zhengshun Song, Yanzhong Hu
Pages: 2313-2321
Published online on: 08 September 2014

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Article Open Access

Increased gastric chromogranin A cell density following changes to diets of patients with irritable bowel syndrome

Tarek Mazzawi, Doris Gundersen, Trygve Hausken, Magdy El‑Salhy
Pages: 2322-2336
Published online on: 18 August 2014

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Article

Suppression of scinderin modulates epithelial‑mesenchymal transition markers in highly metastatic gastric cancer cell line SGC‑7901

Xiao‑Min Chen, Jun‑Ming Guo, Ping Chen, Lian‑Gang Mao, Wei‑Yun Feng, Dong‑Hai Le, Ke‑Qiang Li
Pages: 2327-2333
Published online on: 28 August 2014

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Article Open Access

Opposite effects of cefoperazone and ceftazidime on S‑ribosylhomocysteine lyase/autoinducer-2 quorum sensing and biofilm formation by an Escherichia coli clinical isolate

Hui-Qing Shi, Feng-Jun Sun, Jian-Hong Chen, Xiao-Lan Yong, Qian-Yi Ou, Wei Feng, Pei-Yuan Xia
Pages: 2334-2340
Published online on: 05 September 2014

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Article Open Access

Antibacterial mechanism of fraxetin against Staphylococcus aureus

Haiting Wang, Dan Zou, Kunpeing Xie, Mingjie Xie
Pages: 2341-2345
Published online on: 02 September 2014

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Article Open Access

Metformin combined with p38 MAPK inhibitor improves cisplatin sensitivity in cisplatin‑resistant ovarian cancer

Ya Xie, Zheng Peng, Mingxing Shi, Mei Ji, Hongjun Guo, Huirong Shi
Pages: 2346-2350
Published online on: 14 August 2014

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Article Open Access

Liraglutide reduces lipid accumulation in steatotic L‑02 cells by enhancing autophagy

Shi‑Wei Zhou, Man Zhang, Min Zhu
Pages: 2351-2357
Published online on: 15 September 2014

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Article Open Access

Desmocollin‑2 affects the adhesive strength and cytoskeletal arrangement in esophageal squamous cell carcinoma cells

Wang‑Kai Fang, Lian‑Di Liao, Fa‑Min Zeng, Pi‑Xian Zhang, Jian‑Yi Wu, Jian Shen, Li‑Yan Xu, En‑Min Li
Pages: 2358-2364
Published online on: 12 August 2014

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Article Open Access

Induction of human chronic myeloid leukemia K562 cell apoptosis by virosecurinine and its molecular mechanism

Gang Zhang, Maidong Li, Shuwen Han, Dongyun Chen, Ying Wang, Wencai Ye, Zhaoning Ji
Pages: 2365-2371
Published online on: 03 September 2014

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Article

Effects of combining low‑dose aspirin with a Chinese patent medicine on follicular blood flow and pregnancy outcome

Yue Zhao, Botao Du, Xiaoying Jiang, Mingxing Ma, Liqing Shi, Qinxi Zhang, Lili Zhou
Pages: 2372-2376
Published online on: 16 September 2014

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Article

Toll-like receptor (TLR) expression and TLR‑mediated interleukin-8 production by human submandibular gland epithelial cells

Kouji Ohta, Yoko Ishida, Akiko Fukui, Kuniko Mizuta, Hiromi Nishi, Masaaki Takechi, Nobuyuki Kamata
Pages: 2377-2382
Published online on: 21 August 2014

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Article

Clinical characteristics and pathogenesis of cerebellar glioblastoma

Yoshinobu Takahashi, Keishi Makino, Hideo Nakamura, Takuichiro  Hide, Shigetoshi Yano, Hajime Kamada, Jun-Ichi Kuratsu
Pages: 2383-2388
Published online on: 09 September 2014

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Article

Involvement of IL‑10 and granulocyte colony‑stimulating factor in the fate of monocytes controlled by galectin‑1

Da‑En Cheng, Wei‑An Chang, Jen‑Yu Hung, Ming‑Shyan Huang, Po‑Lin Kuo
Pages: 2389-2394
Published online on: 16 September 2014

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Article

MicroRNA-193b is a regulator of amyloid precursor protein in the blood and cerebrospinal fluid derived exosomal microRNA-193b is a biomarker of Alzheimer's disease

Chen-Geng Liu, Jing Song, Yue-Qi Zhang, Pei-Chang Wang
Pages: 2395-2400
Published online on: 12 August 2014

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Article

MicroRNA-185 suppresses growth and invasion of colon cancer cells through inhibition of the hypoxia‑inducible factor-2α pathway in vitro and in vivo

Zhan-Jun Lu, Lun-Gen Lu, Kai-Zhong Tao, Da-Fan Chen, Qing Xia, Jian‑Jun Weng, Feng Zhu, Xing-Peng Wang, Ping Zheng
Pages: 2401-2408
Published online on: 12 September 2014

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Article

PDGF regulates chondrocyte proliferation through activation of the GIT1- and PLCγ1-mediated ERK1/2 signaling pathway

Jin Xiao, Xuqiong Chen, Lipeng Xu, Ying Zhang, Qingshui Yin, Fei Wang
Pages: 2409-2414
Published online on: 21 August 2014

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Article

Screening of diagnostic markers for osteosarcoma

Dajiang Wu, Kai Chen, Yushu Bai, Xiaodong Zhu, Ziqiang Chen, Chuanfeng Wang, Yingchuan Zhao, Ming Li
Pages: 2415-2420
Published online on: 08 September 2014

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Article

Differential co-expression analysis of rheumatoid arthritis with microarray data

Kunpeng Wang, Liqiang Zhao, Xuefeng Liu, Zhenyong Hao, Yong Zhou, Chuandong Yang, Hongqiang Li
Pages: 2421-2426
Published online on: 14 August 2014

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Article

Effects of infrasound on the growth of bone marrow mesenchymal stem cells: A pilot study

Renhong He, Jianzhong Fan
Pages: 2427-2432
Published online on: 21 August 2014

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Article

Estrogen stimulates the invasion of ovarian cancer cells via activation of the PI3K/AKT pathway and regulation of its downstream targets E‑cadherin and α‑actinin‑4

Zhiying Lu, Ying Zhang, Xiaohui Yan, Yisong Chen, Xiang Tao, Jiajia Wang, Nan Jia, Tianjiao Lyu, Junyan Wang, Jingxin Ding, Weiwei Feng, Keqin Hua
Pages: 2433-2440
Published online on: 12 September 2014

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Article

Learning curve for endobronchial ultrasound‑guided transbronchial needle aspiration: Experience of a community‑based teaching hospital

He Wang, Cyril D'Cruz, David C. Yam, Lorie M. Dilla, Patricia Tsang
Pages: 2441-2446
Published online on: 03 September 2014

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Article

Exenatide enhances INS-1 rat pancreatic β‑cell mass by increasing the protein levels of adiponectin and reducing the levels of C-reactive protein

Huibiao Quan, Yongyi Gao, Huachuan Zhang, Tuanyu Fang, Daoxiong Chen, Zhaohui Lv, Yanming Chen
Pages: 2447-2452
Published online on: 05 September 2014

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Article

Function of ghrelin and ghrelin receptors in the network regulation of gastric motility

Cheng-Guang Yang, Zuo-Fu Liao, Wen-Cai Qiu, Jun Yan, Zhi-Gang Wang
Pages: 2453-2458
Published online on: 16 September 2014

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Article

Calcium/calmodulin‑dependent protein kinase II enhances metastasis of human gastric cancer by upregulating nuclear factor‑κB and Akt‑mediated matrix metalloproteinase‑9 production

Zhaolong Liu, Gang Han, Yu Cao, Yidong Wang, Hangjun Gong
Pages: 2459-2464
Published online on: 28 August 2014

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Article

Detection of chromosomal abnormalities and the 22q11 microdeletion in fetuses with congenital heart defects

Wei Lv, Shuyu Wang
Pages: 2465-2470
Published online on: 12 September 2014

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Article

Role of the TGFβ/p65 pathway in tanshinone ⅡA-treated HBZY‑1 cells

Gangyi Chen, Xingju Zhang, Chao Li, Yingying Lin, Yu Meng, Shuifu Tang
Pages: 2471-2476
Published online on: 18 August 2014

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Article

Antitumor effect of a copper (II) complex of a coumarin derivative and phenanthroline on lung adenocarcinoma cells and the mechanism of action

Taofeng Zhu, Ruhua Chen, Hao Yu, Yan Feng, Jianqiang  Chen, Qin Lu, Jing Xie, Weiliang Ding, Tieliang Ma
Pages: 2477-2482
Published online on: 26 August 2014

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Article

Novel mechanism of intra‑renal angiotensin II-induced sodium/proton exchanger 3 expression by losartan in spontaneously hypertensive rats

Xiaoqin Fan, Kaishan Liu, Wei Cui, Jiongmei Huang, Weina Wang, Yuan Gao
Pages: 2483-2488
Published online on: 14 August 2014

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Article

FOS-like antigen 1 is highly expressed in human psoriasis tissues and promotes the growth of HaCaT cells in vitro

Wu Zhu, Jing Li, Juan Su, Jie Li, Jinmao Li, Bo Deng, Qian Shi, Yanhong Zhou, Xiang Chen
Pages: 2489-2494
Published online on: 21 August 2014

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Article

Stem cell characteristics of dormant cells and cisplatin‑induced effects on the stemness of epithelial ovarian cancer cells

Nan Zhou, Xiaohua Wu, Bo Yang, Xu Yang, Dingding Zhang, Guo Qing
Pages: 2495-2504
Published online on: 12 August 2014

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Article

Curcumin inhibits hypoxia inducible factor‑1α‑induced epithelial‑mesenchymal transition in HepG2 hepatocellular carcinoma cells

Wanxing Duan, Yuanhong Chang, Rong Li, Qinhong Xu, Jianjun Lei, Caiqiao Yin, Ting Li, Yanzhao Wu, Qingyong Ma, Xuqi Li
Pages: 2505-2510
Published online on: 09 September 2014

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Article

A proteomics study of hyperhomocysteinemia injury of the hippocampal neurons using iTRAQ

Min Fang, Jing Wang, Han Yan, Yan‑Xin Zhao, Xue‑Yuan Liu
Pages: 2511-2516
Published online on: 11 September 2014

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Article

Inhibition of Rho-kinase by fasudil restores the cardioprotection of ischemic postconditioninng in hypercholesterolemic rat heart

Nan Wu, Wenna Li, Wenqi Shu, Yan Lv, Dalin Jia
Pages: 2517-2524
Published online on: 15 September 2014

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Article

Duhuo Jisheng Decoction‑containing serum promotes proliferation of interleukin‑1β‑induced chondrocytes through the p16‑cyclin D1/CDK4‑Rb pathway

Guangwen Wu, Huailing Fan, Yuanpeng Huang, Chunsong Zheng, Jinxia Ye, Xianxiang Liu
Pages: 2525-2534
Published online on: 02 September 2014

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Article

Synergistic effects of puerarin combined with 5-fluorouracil on esophageal cancer

Jun Wang, Zi-Rong Yang, Xu-Feng Guo, Jia Song, Ji‑Xiang  Zhang, Jing Wang, Wei-Guo Dong
Pages: 2535-2541
Published online on: 05 September 2014

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Article

Resveratrol attenuates hypoxia/reoxygenation‑induced Ca2+ overload by inhibiting the Wnt5a/Frizzled‑2 pathway in rat H9c2 cells

Xiang Wu, Shanshan Zhou, Ning Zhu, Xianbao Wang, Wen Jin, Xudong Song, Aihua Chen
Pages: 2542-2548
Published online on: 14 August 2014

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Article

All-trans retinoic acid suppresses apoptosis in PC12 cells injured by oxygen and glucose deprivation via the retinoic acid receptor α signaling pathway

Xiaojian Zhang, Qin Yu, Wei Jiang, Yang Bi, Yun Zhang, Min Gong, Xiaoping Wei, Tingyu Li, Jie Chen
Pages: 2549-2555
Published online on: 15 September 2014

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Article

Saikosaponin‑d suppresses the expression of cyclooxygenase‑2 through the phospho‑signal transducer and activator of transcription 3/hypoxia‑inducible factor‑1α pathway in hepatocellular carcinoma cells

Shuixiang He, Guifang Lu, Helei Hou, Zhenjun Zhao, Zhanfang Zhu, Xinlan Lu, Jinghong Chen, Zhilun Wang
Pages: 2556-2562
Published online on: 16 September 2014

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Article

Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway

Yong Qin, Zhenhua Ma, Xiaoyan Dang, Wei Li, Qingyong Ma
Pages: 2563-2567
Published online on: 21 August 2014

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Article

Synergy of urokinase‑type plasminogen activator receptor isomer (D1D2) and integrin α5β1 causes malignant transformation of hepatic cells and the occurrence of liver cancer

Ying-Qun Zhou, Xiao-Ping Lv, Shan Li, Bing Bai, Ling-Ling Zhan
Pages: 2568-2574
Published online on: 20 August 2014

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Article

Low expression of microRNA-30c promotes invasion by inducing epithelial mesenchymal transition in non-small cell lung cancer

Zhaopeng Zhong, Yang Xia, Pengli Wang, Bin Liu, Yijiang Chen
Pages: 2575-2579
Published online on: 14 August 2014

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Article

Hepatitis B virus inhibits the expression of CD82 through hypermethylation of its promoter in hepatoma cells

Guozheng Yu, Yuntao Bing, Wei Li, Lin Xia, Zhisu Liu
Pages: 2580-2586
Published online on: 14 August 2014

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Article

Liraglutide ameliorates renal injury in streptozotocin‑induced diabetic rats by activating endothelial nitric oxide synthase activity via the downregulation of the nuclear factor‑κB pathway

Sai‑Jun Zhou, Lian Bai, Lin Lv, Rui Chen, Chun‑Jun Li, Xiang‑Yang Liu, De‑Min Yu, Pei Yu
Pages: 2587-2594
Published online on: 10 September 2014

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Article

TET1 partially mediates HDAC inhibitor-induced suppression of breast cancer invasion

Hou-Gen Lu, Wang Zhan, Lin Yan, Rui-Ying Qin, Yi-Peng Yan, Zhen-Jiang Yang, Gui‑Chao  Liu, Gui-Qin Li, Hai-Feng Wang, Xing-Liang Li, Zhi Li, Lu Gao, Guo-Qing Chen
Pages: 2595-2600
Published online on: 26 August 2014

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Article

Reduced miR-125a-5p expression is associated with gastric carcinogenesis through the targeting of E2F3

Yanjun Xu, Zhenxia Huang, Yueli Liu
Pages: 2601-2608
Published online on: 15 September 2014

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Article

Dyclonine enhances the cytotoxic effect of proteasome inhibitor bortezomib in multiple myeloma cells

Donghong Ju, Youming Xie
Pages: 2609-2612
Published online on: 28 August 2014

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Article

miR-193b directly targets STMN1 and uPA genes and suppresses tumor growth and metastasis in pancreatic cancer

Jian Li, Fujiao Kong, Kemin Wu, Kun Song, Jianfeng He, Weijia Sun
Pages: 2613-2620
Published online on: 11 September 2014

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Article

CADM1/TSLC1 inhibits melanoma cell line A375 invasion through the suppression of matrix metalloproteinases

Yan You, Jinfeng Zhang, Yulian Li, Yuzhen Li, Guangyue Shi, Langjuan Ma, Haiying Wei
Pages: 2621-2626
Published online on: 11 September 2014

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Article

Piperine effectively protects primary cultured atrial myocytes from oxidative damage in the infant rabbit model

Yongjiang Ma, Miao Tian, Pin Liu, Ziling Wang, Yuan Guan, Yan Liu, Yutang Wang, Zhaoliang Shan
Pages: 2627-2632
Published online on: 10 September 2014

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Genome-wide identification and expression analysis of microRNA involved in small cell lung cancer via deep sequencing

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MicroRNA-195 acts as a tumor suppressor by directly targeting Wnt3a in HepG2 hepatocellular carcinoma cells

Yang Yang, Menghe Li, Su'e Chang, Lumin Wang, Tusheng Song, Ling  Gao, Lili Hu, Zongfang Li, Liying Liu, Jiayi Yao, Chen Huang
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Aberrant expression of p-STAT3 in peripheral blood CD4+ and CD8+ T cells related to hepatocellular carcinoma development

Xu Wang, Wenbin Xin, Hua Zhang, Fengmei Zhang, Meilan Gao, Lingling Yuan, Xiaoyan Xu, Xuemei Hu, Mingdong Zhao
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An enhanced immune response against G250, induced by a heterologous DNA prime‑protein boost vaccination, using polyethyleneimine as a DNA vaccine adjuvant

Zeqiang Sun, Bo Liu, Xiyun Ruan, Qingyong Liu
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Methanol extracts of Euphorbia cooperi inhibit the production of inflammatory mediators by inhibiting the activation of c‑Jun N‑terminal kinase and p38 in murine macrophages

Young‑Chang Cho, In‑Seon Lee, Huiyun Seo, Anna Ju, Deokkyu  Youn, Younghyun Kim, Jaehee Choun, Sayeon Cho
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Comparison of immunohistochemistry, four in situ hybridization methods and quantitative polymerase chain reaction for the molecular diagnosis of HER2 status in gastric cancer: A study of 55 cases

Libor Staněk, Tomáš Rozkoš, Jan Laco, Aleš Ryška, Luboš  Petruželka, Miroslav Důra, Pavel Dundr
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Phenethyl isothiocyanate suppresses cervical carcinoma metastasis potential and its molecular mechanism

Li Zhang, Quan Hao, Lewen Bao, Wenxin Liu, Xin Fu, Ying Chen, Huijuan Wu
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Preliminary detection of the anti‑tumour activity of indoline‑2,3‑dione derivative DH‑12a targeting aminopeptidase N

De‑Xuan Cui, Xue‑Jian Wang, Xiu‑Rong Zhang, Ting‑Kun Zhao, Xiu‑Xiang Guo, Shun‑Mei Liu, Bing Wang, Wen‑Quan Ma, Zhi‑Qin Gao
Pages: 2681-2688
Published online on: 09 September 2014

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Flavonoid content, free radical scavenging and increase in xanthine oxidase inhibitory activity in Galgeun-tang following fermentation with Lactobacillus plantarum

Dong-Seon Kim, Young Ran Um, Jin Yeul Ma
Pages: 2689-2693
Published online on: 13 August 2014

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Evaluation of respiratory impedance in patients with chronic obstructive pulmonary disease by an impulse oscillation system

Su‑Gang Gong, Wen‑Lan Yang, Wei Zheng, Jin‑Ming Liu
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Published online on: 02 September 2014

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Effect of adenovirus‑mediated uPA gene transduction on the fibrinolytic activity of human umbilical vein endothelial cells

Weimin Zhou
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Published online on: 26 August 2014

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MTHFR polymorphisms and serum cobalamin affect plasma homocysteine concentrations differentially in females and males

Torbjörn K. Nilsson, Anna K. Böttiger, Patricia Henríquez, Lluís Serra Majem
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Effects of all‑trans retinoic acid on VEGF and HIF‑1α expression in glioma cells under normoxia and hypoxia and its anti‑angiogenic effect in an intracerebral glioma model

Chen Liang, Shiwen Guo, Ling Yang
Pages: 2713-2719
Published online on: 05 September 2014

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Knockdown of Y‑box‑binding protein‑1 inhibits the malignant progression of HT‑29 colorectal adenocarcinoma cells by reversing epithelial‑mesenchymal transition

Xue‑Bing Yan, Qing‑Chao Zhu, Hong‑Qi Chen, Jia‑Yuan Peng, Hong‑Lei  Chao, Hang‑Xiang Du, Zhi‑Gang Wang, Zhi‑Ming Jin
Pages: 2720-2728
Published online on: 05 September 2014

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Suberoylanilide hydroxamic acid enhances the antitumor activity of oxaliplatin by reversing the oxaliplatin‑induced Src activation in gastric cancer cells

Chenfei Zhou, Jun Ji, Min Shi, Liu Yang, Yingyan Yu, Bingya Liu, Zhenggang Zhu, Jun Zhang
Pages: 2729-2735
Published online on: 09 September 2014

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Association study of miR‑149 rs2292832 and miR‑608 rs4919510 and the risk of hepatocellular carcinoma in a large‑scale population

Rui Wang, Jun Zhang, Yanyun Ma, Linqi Chen, Shicheng Guo, Xiaojiao Zhang, Yunfang Ma, Lijun Wu, Xiaoyu Pei, Siran Liu, Jiucun Wang, Heping Hu, Jie Liu
Pages: 2736-2744
Published online on: 04 September 2014

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Different concentrations of 17β-estradiol modulates apoptosis induced by interleukin-1β in rat annulus fibrosus cells

Haiying Wang, Wenyuan Ding, Dalong Yang, Tixin Gu, Sidong Yang, Zhilong Bai
Pages: 2745-2751
Published online on: 22 August 2014

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Puerarin inhibits growth and induces apoptosis in SMMC-7721 hepatocellular carcinoma cells

Wei-Guo Zhang, Xiao-Fang Liu, Ke-Wei Meng, San-Yuan Hu
Pages: 2752-2758
Published online on: 21 August 2014

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Peroxisome proliferator‑activated receptor γ polymorphisms as risk factors for dyslipidemia

Shu‑Jun Gu, Zhi‑Rong Guo, Zheng‑Yuan Zhou, Xiao‑Shu Hu, Ming Wu, Ning Zhang
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Published online on: 10 September 2014

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Tanshinol protects human umbilical vein endothelial cells against hydrogen peroxide‑induced apoptosis

Wei Song, Jun Pu, Ben He
Pages: 2764-2770
Published online on: 05 September 2014

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Article Number: 50
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Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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