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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2022 Volume 25 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Knockdown of DPP4 promotes the proliferation and the activation of the CREB/aromatase pathway in ovarian granulosa cells

Lina Lin, Liman Wang
Article Number: 73
Published online on: 07 January 2022

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Inhibition of FOXO1‑mediated autophagy promotes paclitaxel‑induced apoptosis of MDA‑MB‑231 cells

Kaixiang Xu, Wanyun Zhu, Anyong Xu, Zhe Xiong, Di Zou, Heng Zhao, Deling Jiao, Yubo Qing, Muhammad Ameen Jamal, Hong-Jiang Wei, Hong-Ye Zhao
Article Number: 72
Published online on: 05 January 2022

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Long non‑coding RNA LINC00238 suppresses the malignant phenotype of liver cancer by sponging miR‑522 Corrigendum in /10.3892/mmr.2024.13189

Hong-Gang Qian, Qiong Wu, Jian-Hui Wu, Xiu-Yun Tian, Wei Xu, Chun-Yi Hao
Article Number: 71
Published online on: 05 January 2022

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Activation of neurotrophin signalling with light‑inducible receptor tyrosine kinases

Wei Zhang, Shu Zhao, Linjie Lu, Zhimin Fan, Shixin Ye
Article Number: 70
Published online on: 05 January 2022

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Correction Open Access

[Corrigendum] Silencing of RIPK4 inhibits epithelial‑mesenchymal transition by inactivating the Wnt/β‑catenin signaling pathway in osteosarcoma

Zhigang Yi, Yanchuan Pu, Ruoyan Gou, Yonggang Chen, Xiaojun Ren, Wenzhong Liu, Ping Dong
Article Number: 69
Published online on: 04 January 2022

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Retraction Open Access

[Retracted] Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

Dan Li, Zhitao Xiao, Gang Wang, Xianji Song
Article Number: 68
Published online on: 04 January 2022

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Article Open Access

lncRNA GMDS‑AS1 upregulates IL‑6, TNF‑α and IL‑1β, and induces apoptosis in human monocytic THP‑1 cells via miR‑96‑5p/caspase 2 signaling

Lei Jiang, Jinghui Li
Article Number: 67
Published online on: 03 January 2022

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Long non-coding RNA NEAT1 participates in ventilator-induced lung injury by regulating miR-20b expression

Yi Liu, Gang Tang, Jinyu Li
Article Number: 66
Published online on: 03 January 2022

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Inside the chronic lymphocytic leukemia cell: miRNA and chromosomal aberrations

Anna Grenda, Agata A. Filip, Ewa Wąsik‑Szczepanek
Article Number: 65
Published online on: 03 January 2022

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De novo assembly and transcriptome characterization: Novel insights into the mechanisms of primary ovarian cancer in Microtus fortis

Qi Hu, Mingyue Gao, Du Zhang, Bingfeng Leng, Junwen Wang, Qian Liu, Shuangyan He, Wenling Zhi, Zhijun Zhou
Article Number: 64
Published online on: 27 December 2021

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CD4+/IL‑4+ lymphocytes of the lamina propria and substance P promote colonic protection during acute stress

Ivonne Maciel Arciniega‑Martínez, Aldo Arturo Reséndiz Albor, Luz María Cárdenas Jaramillo, Juan Manuel Gutiérrez‑Meza, Ramcés Falfán‑Valencia, Belen Mendoza Arroyo, Mariazell Yépez‑Ortega, Judith Pacheco‑Yépez, Edgar Abarca‑Rojano
Article Number: 63
Published online on: 27 December 2021

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MicroRNA‑126 protects SH‑SY5Y cells from ischemia/reperfusion injury‑induced apoptosis by inhibiting RAB3IP

Zhumei Sun, Xu Zhao, Meihang Zhang, Ning Li, Yanning Zhao, Changxiang Chen, Jianmin Li, Yanjuan Guo, Qiang Feng
Article Number: 62
Published online on: 20 December 2021

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Inhibitory effect of miR‑182‑5p on retinal neovascularization by targeting angiogenin and BDNF

Chenyue Li, Hongxuan Lie, Weifeng Sun
Article Number: 61
Published online on: 20 December 2021

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Dichloromethane fractions of Calystegia soldanella induce S‑phase arrest and apoptosis in HT‑29 human colorectal cancer cells

In-Hye Kim, Taekil Eom, Joon-Young Park, Hyung-Joo Kim, Taek-Jeong Nam
Article Number: 60
Published online on: 17 December 2021

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Zoledronic acid inhibits osteoclastogenesis and bone resorptive function by suppressing RANKL‑mediated NF‑κB and JNK and their downstream signalling pathways

Xiao-Lin Huang, Chao Liu, Xue-Mei Shi, Yu-Ting Cheng, Qian Zhou, Jian-Ping Li, Jian Liao
Article Number: 59
Published online on: 17 December 2021

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Article

5‑Aminosalicylic acid attenuates paraquat‑induced lung fibroblast activation and pulmonary fibrosis of rats

Hui Chen, Jinfeng Cui, Juan Wang, Yuan Wang, Fei Tong, Yingping Tian, Yu Gong, Yu Ma, Liang Liu, Xianghong Zhang
Article Number: 58
Published online on: 15 December 2021

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Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice

Ching-Chuan Yeh, Hsuan-Miao Liu, Ming-Chung Lee, Yann-Lii Leu, Wei-Han Chiang, Hen-Hong Chang, Tzung-Yan Lee
Article Number: 57
Published online on: 15 December 2021

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Knockdown of CCL28 inhibits endometriosis stromal cell proliferation and invasion via ERK signaling pathway inactivation

Yingting Wu, Feilong Zhu, Wenqin Sun, Weiwei Shen, Qin Zhang, Huifen Chen
Article Number: 56
Published online on: 15 December 2021

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Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway

Wenqian Tang, Juan Xue, Lei Luo, Yao Wang, Xin Cai, Yuqing Liu, Dawei Huang, Xiaodong Wang, Tangqing He, Dingbo Lu, Fan Yang
Article Number: 55
Published online on: 15 December 2021

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Article Open Access

HMGA2 promotes the migration and invasion of gallbladder cancer cells and HMGA2 knockdown inhibits angiogenesis via targeting VEGFA

Jun Yan, Peng Dai, Xueliang Qin, Yanping He, Yu Zhang
Article Number: 54
Published online on: 15 December 2021

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AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway

Jianping Zheng, Changhao Liu, Jiandang Shi, Kun Wen, Xiangxin Wang
Article Number: 53
Published online on: 14 December 2021

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Weilan gum oligosaccharide ameliorates dextran sulfate sodium‑induced experimental ulcerative colitis

Ping Zhang, Le Su, Feifan Ma, Xiuyu Ji, Yue Su, Qiulin Yue, Chen Zhao, Song Zhang, Xin Sun, Lin Zhao
Article Number: 52
Published online on: 13 December 2021

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CircRNA_0044556 diminishes the sensitivity of triple‑negative breast cancer cells to adriamycin by sponging miR‑145 and regulating NRAS

Jingjing Chen, Peng Shi, Jinghua Zhang, Yufeng Li, Jie Ma, Yudong Zhang, Hong Liu
Article Number: 51
Published online on: 13 December 2021

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Substance P prevents doxorubicin‑induced cardiomyocyte injury by regulating apoptosis and autophagy: In vitro and in vivo evidence

Fa-Xiu Chen, Qin Wan, Qing-Ling Li, Jing Fang, Le Peng, Jian Hu
Article Number: 50
Published online on: 13 December 2021

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Oxidative stress and expression of inflammatory factors in lung tissue of acute mountain sickness rats

Xiaoyan Pu, Fuxin Li, Xue Lin, Rong Wang, Zhi Chen
Article Number: 49
Published online on: 09 December 2021

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Article Open Access

Rapid detection of FMO3 single nucleotide polymorphisms using a pyrosequencing method

Jin-Woo Park, In-Hwan Park, Jong-Min Kim, Ji Hyeon Noh, Kyoung-Ah Kim, Ji-Young Park
Article Number: 48
Published online on: 08 December 2021

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Analysis of a family with mitochondrial trifunctional protein deficiency caused by HADHA gene mutations

Jinling Yang, Dejian Yuan, Xiaohui Tan, Yexi Zeng, Ning Tang, Dayu Chen, Jianqiang Tan, Ren Cai, Jun Huang, Tizhen Yan
Article Number: 47
Published online on: 08 December 2021

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Long non‑coding RNA HCG18 facilitates the progression of laryngeal and hypopharyngeal squamous cell carcinoma by upregulating FGFR1 via miR‑133b

Hongbin Peng, Pingjiang Ge
Article Number: 46
Published online on: 08 December 2021

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Article

Two novel biallelic mutations in PSMC3IP in a patient affected by premature ovarian insufficiency

Libin Mei, Lingling Huang, Yanru Huang, Xiaoling Wu, Huang He, Xuemei He, Zhiying Su, Ping Li
Article Number: 45
Published online on: 08 December 2021

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Review Open Access

Opioids in cancer: The κ‑opioid receptor (Review)

Qier Zhou, Zhiwei Zhang, Songkai Long, Wanjun Li, Baiyun Wang, Na Liang
Article Number: 44
Published online on: 08 December 2021

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Article

Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss

Zhuhua Cai, Xiuying Zheng, Yan Chen, Fengdan Chen, Liangmiao Chen, Xiaohui Deng
Article Number: 43
Published online on: 07 December 2021

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Article

Analysis of differentially expressed long non‑coding RNAs revealed a pro‑tumor role of MIR205HG in cervical cancer

Lu Yin, Yi Zhang, Leizhen Zheng
Article Number: 42
Published online on: 07 December 2021

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Review Open Access

HIF‑1α in cerebral ischemia (Review)

Peiliang Dong, Qingna Li, Hua Han
Article Number: 41
Published online on: 07 December 2021

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IRF2 contributes to myocardial infarction via regulation of GSDMD induced pyroptosis

Yongxing Li, Yan Wang, Hua Guo, Qinghua Wu, Yamin Hu
Article Number: 40
Published online on: 06 December 2021

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Correction Open Access

[Corrigendum] miR‑593 inhibits proliferation and invasion and promotes apoptosis in non‑small cell lung cancer cells by targeting SLUG‑associated signaling pathways

Fang Wei, Mofei Wang, Zhen Li, Yong Wang, Yong Zhou
Article Number: 39
Published online on: 06 December 2021

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
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Published online on: 05 January 2026

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Article Open Access

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Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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