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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2022 Volume 25 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Knockdown of DPP4 promotes the proliferation and the activation of the CREB/aromatase pathway in ovarian granulosa cells

Lina Lin, Liman Wang
Article Number: 73
Published online on: 07 January 2022

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Inhibition of FOXO1‑mediated autophagy promotes paclitaxel‑induced apoptosis of MDA‑MB‑231 cells

Kaixiang Xu, Wanyun Zhu, Anyong Xu, Zhe Xiong, Di Zou, Heng Zhao, Deling Jiao, Yubo Qing, Muhammad Ameen Jamal, Hong-Jiang Wei, Hong-Ye Zhao
Article Number: 72
Published online on: 05 January 2022

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Long non‑coding RNA LINC00238 suppresses the malignant phenotype of liver cancer by sponging miR‑522 Corrigendum in /10.3892/mmr.2024.13189

Hong-Gang Qian, Qiong Wu, Jian-Hui Wu, Xiu-Yun Tian, Wei Xu, Chun-Yi Hao
Article Number: 71
Published online on: 05 January 2022

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Activation of neurotrophin signalling with light‑inducible receptor tyrosine kinases

Wei Zhang, Shu Zhao, Linjie Lu, Zhimin Fan, Shixin Ye
Article Number: 70
Published online on: 05 January 2022

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Correction Open Access

[Corrigendum] Silencing of RIPK4 inhibits epithelial‑mesenchymal transition by inactivating the Wnt/β‑catenin signaling pathway in osteosarcoma

Zhigang Yi, Yanchuan Pu, Ruoyan Gou, Yonggang Chen, Xiaojun Ren, Wenzhong Liu, Ping Dong
Article Number: 69
Published online on: 04 January 2022

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Retraction Open Access

[Retracted] Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

Dan Li, Zhitao Xiao, Gang Wang, Xianji Song
Article Number: 68
Published online on: 04 January 2022

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Article Open Access

lncRNA GMDS‑AS1 upregulates IL‑6, TNF‑α and IL‑1β, and induces apoptosis in human monocytic THP‑1 cells via miR‑96‑5p/caspase 2 signaling

Lei Jiang, Jinghui Li
Article Number: 67
Published online on: 03 January 2022

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Long non-coding RNA NEAT1 participates in ventilator-induced lung injury by regulating miR-20b expression

Yi Liu, Gang Tang, Jinyu Li
Article Number: 66
Published online on: 03 January 2022

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Inside the chronic lymphocytic leukemia cell: miRNA and chromosomal aberrations

Anna Grenda, Agata A. Filip, Ewa Wąsik‑Szczepanek
Article Number: 65
Published online on: 03 January 2022

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De novo assembly and transcriptome characterization: Novel insights into the mechanisms of primary ovarian cancer in Microtus fortis

Qi Hu, Mingyue Gao, Du Zhang, Bingfeng Leng, Junwen Wang, Qian Liu, Shuangyan He, Wenling Zhi, Zhijun Zhou
Article Number: 64
Published online on: 27 December 2021

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CD4+/IL‑4+ lymphocytes of the lamina propria and substance P promote colonic protection during acute stress

Ivonne Maciel Arciniega‑Martínez, Aldo Arturo Reséndiz Albor, Luz María Cárdenas Jaramillo, Juan Manuel Gutiérrez‑Meza, Ramcés Falfán‑Valencia, Belen Mendoza Arroyo, Mariazell Yépez‑Ortega, Judith Pacheco‑Yépez, Edgar Abarca‑Rojano
Article Number: 63
Published online on: 27 December 2021

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MicroRNA‑126 protects SH‑SY5Y cells from ischemia/reperfusion injury‑induced apoptosis by inhibiting RAB3IP

Zhumei Sun, Xu Zhao, Meihang Zhang, Ning Li, Yanning Zhao, Changxiang Chen, Jianmin Li, Yanjuan Guo, Qiang Feng
Article Number: 62
Published online on: 20 December 2021

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Inhibitory effect of miR‑182‑5p on retinal neovascularization by targeting angiogenin and BDNF

Chenyue Li, Hongxuan Lie, Weifeng Sun
Article Number: 61
Published online on: 20 December 2021

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Dichloromethane fractions of Calystegia soldanella induce S‑phase arrest and apoptosis in HT‑29 human colorectal cancer cells

In-Hye Kim, Taekil Eom, Joon-Young Park, Hyung-Joo Kim, Taek-Jeong Nam
Article Number: 60
Published online on: 17 December 2021

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Zoledronic acid inhibits osteoclastogenesis and bone resorptive function by suppressing RANKL‑mediated NF‑κB and JNK and their downstream signalling pathways

Xiao-Lin Huang, Chao Liu, Xue-Mei Shi, Yu-Ting Cheng, Qian Zhou, Jian-Ping Li, Jian Liao
Article Number: 59
Published online on: 17 December 2021

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Article

5‑Aminosalicylic acid attenuates paraquat‑induced lung fibroblast activation and pulmonary fibrosis of rats

Hui Chen, Jinfeng Cui, Juan Wang, Yuan Wang, Fei Tong, Yingping Tian, Yu Gong, Yu Ma, Liang Liu, Xianghong Zhang
Article Number: 58
Published online on: 15 December 2021

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Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice

Ching-Chuan Yeh, Hsuan-Miao Liu, Ming-Chung Lee, Yann-Lii Leu, Wei-Han Chiang, Hen-Hong Chang, Tzung-Yan Lee
Article Number: 57
Published online on: 15 December 2021

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Knockdown of CCL28 inhibits endometriosis stromal cell proliferation and invasion via ERK signaling pathway inactivation

Yingting Wu, Feilong Zhu, Wenqin Sun, Weiwei Shen, Qin Zhang, Huifen Chen
Article Number: 56
Published online on: 15 December 2021

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Kangxianruangan granule‑containing serum mediated inhibition of hepatic oval cell differentiation into hepatocellular carcinoma cells via the Wnt‑1/β‑catenin signaling pathway

Wenqian Tang, Juan Xue, Lei Luo, Yao Wang, Xin Cai, Yuqing Liu, Dawei Huang, Xiaodong Wang, Tangqing He, Dingbo Lu, Fan Yang
Article Number: 55
Published online on: 15 December 2021

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HMGA2 promotes the migration and invasion of gallbladder cancer cells and HMGA2 knockdown inhibits angiogenesis via targeting VEGFA

Jun Yan, Peng Dai, Xueliang Qin, Yanping He, Yu Zhang
Article Number: 54
Published online on: 15 December 2021

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AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway

Jianping Zheng, Changhao Liu, Jiandang Shi, Kun Wen, Xiangxin Wang
Article Number: 53
Published online on: 14 December 2021

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Article Open Access

Weilan gum oligosaccharide ameliorates dextran sulfate sodium‑induced experimental ulcerative colitis

Ping Zhang, Le Su, Feifan Ma, Xiuyu Ji, Yue Su, Qiulin Yue, Chen Zhao, Song Zhang, Xin Sun, Lin Zhao
Article Number: 52
Published online on: 13 December 2021

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CircRNA_0044556 diminishes the sensitivity of triple‑negative breast cancer cells to adriamycin by sponging miR‑145 and regulating NRAS

Jingjing Chen, Peng Shi, Jinghua Zhang, Yufeng Li, Jie Ma, Yudong Zhang, Hong Liu
Article Number: 51
Published online on: 13 December 2021

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Article Open Access

Substance P prevents doxorubicin‑induced cardiomyocyte injury by regulating apoptosis and autophagy: In vitro and in vivo evidence

Fa-Xiu Chen, Qin Wan, Qing-Ling Li, Jing Fang, Le Peng, Jian Hu
Article Number: 50
Published online on: 13 December 2021

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Oxidative stress and expression of inflammatory factors in lung tissue of acute mountain sickness rats

Xiaoyan Pu, Fuxin Li, Xue Lin, Rong Wang, Zhi Chen
Article Number: 49
Published online on: 09 December 2021

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Article Open Access

Rapid detection of FMO3 single nucleotide polymorphisms using a pyrosequencing method

Jin-Woo Park, In-Hwan Park, Jong-Min Kim, Ji Hyeon Noh, Kyoung-Ah Kim, Ji-Young Park
Article Number: 48
Published online on: 08 December 2021

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Analysis of a family with mitochondrial trifunctional protein deficiency caused by HADHA gene mutations

Jinling Yang, Dejian Yuan, Xiaohui Tan, Yexi Zeng, Ning Tang, Dayu Chen, Jianqiang Tan, Ren Cai, Jun Huang, Tizhen Yan
Article Number: 47
Published online on: 08 December 2021

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Long non‑coding RNA HCG18 facilitates the progression of laryngeal and hypopharyngeal squamous cell carcinoma by upregulating FGFR1 via miR‑133b

Hongbin Peng, Pingjiang Ge
Article Number: 46
Published online on: 08 December 2021

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Article

Two novel biallelic mutations in PSMC3IP in a patient affected by premature ovarian insufficiency

Libin Mei, Lingling Huang, Yanru Huang, Xiaoling Wu, Huang He, Xuemei He, Zhiying Su, Ping Li
Article Number: 45
Published online on: 08 December 2021

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Review Open Access

Opioids in cancer: The κ‑opioid receptor (Review)

Qier Zhou, Zhiwei Zhang, Songkai Long, Wanjun Li, Baiyun Wang, Na Liang
Article Number: 44
Published online on: 08 December 2021

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Article

Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss

Zhuhua Cai, Xiuying Zheng, Yan Chen, Fengdan Chen, Liangmiao Chen, Xiaohui Deng
Article Number: 43
Published online on: 07 December 2021

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Article

Analysis of differentially expressed long non‑coding RNAs revealed a pro‑tumor role of MIR205HG in cervical cancer

Lu Yin, Yi Zhang, Leizhen Zheng
Article Number: 42
Published online on: 07 December 2021

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Review Open Access

HIF‑1α in cerebral ischemia (Review)

Peiliang Dong, Qingna Li, Hua Han
Article Number: 41
Published online on: 07 December 2021

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IRF2 contributes to myocardial infarction via regulation of GSDMD induced pyroptosis

Yongxing Li, Yan Wang, Hua Guo, Qinghua Wu, Yamin Hu
Article Number: 40
Published online on: 06 December 2021

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Correction Open Access

[Corrigendum] miR‑593 inhibits proliferation and invasion and promotes apoptosis in non‑small cell lung cancer cells by targeting SLUG‑associated signaling pathways

Fang Wei, Mofei Wang, Zhen Li, Yong Wang, Yong Zhou
Article Number: 39
Published online on: 06 December 2021

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Article Open Access

Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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