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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Article Open Access

Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Review Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Article Open Access

Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Article Open Access

Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Article Open Access

Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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Journal Cover
October-2026 Volume 32 Issue 4

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Efficacy and safety of rituximab in the treatment of primary central nervous system lymphoma: A meta‑analysis and systematic review of 1,388 patients

Lichaoyue Sun, Wenshu Li, Wei Chen, Chunxing Li, Zhao Ren, Qing Xie, Dongxiao Wang
Article Number: 488
Published online on: 02 September 2026

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Review Open Access

Psychological stress and tumor progression: Molecular mechanisms and therapeutic implications (Review)

Yifei Zhang, Yajun Kong, Shuanbao Zhao
Article Number: 487
Published online on: 02 September 2026

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Article Open Access

Development and evaluation of clinical models based on ultrasound, serum CA153 and molecular subtype in predicting the efficacy of neoadjuvant chemotherapy in breast cancer

Ming-Yue Du, Shu-E Zeng
Article Number: 486
Published online on: 02 September 2026

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Article Open Access

Clinical utility of circulating tumor‑derived endothelial cells in lung cancer detection and prognosis prediction

Xiang Li, Jun Yang, Bin Chen, Ziyu Zhang, Jiangman Zhao, Mengxin Zhao, Zhimou Wang
Article Number: 485
Published online on: 02 September 2026

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Article Open Access

Construction of a new predictive model in head and neck squamous cell carcinoma based on the investigation of extracellular matrix‑associated genes

Liangqian Tu, Yiyin Qiu, Handan Zheng, Bixin Fang, Ming Chen
Article Number: 484
Published online on: 02 September 2026

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Review Open Access
Special Issue

Inhibition or induction of gastrointestinal tumors by ferroptosis and intervention by herbal extracts (Review)

Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun
Article Number: 483
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells

Muliang Ding, Jianzhong Hu, Jiangdong Ni, Zhonghui Zheng, Deye Song, Junjie Wang
Article Number: 482
Published online on: 01 September 2026

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Article Open Access

CCT2 defines a highly cisplatin‑resistant and poor‑prognosis subtype of lung adenocarcinoma

Huafang Mao, Chao Su, Xiaoliang Han, Guoxia Wang
Article Number: 481
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Simvastatin potentiates doxorubicin activity against MCF‑7 breast cancer cells

Benjaporn Buranrat, Wanwisa Suwannaloet, Jarinyaporn Naowaboot
Article Number: 480
Published online on: 27 August 2026

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Article Open Access

Characterization of ZIC5 expression in esophageal squamous cell carcinoma and its association with patient survival

Bo Yang, Baige Wang, Haiquan Deng, Yong Luo, Shenghao Wu, Huaxin Yin, Hongdian Zhang, Yuncheng Zhang, Zhen Zhang
Article Number: 479
Published online on: 26 August 2026

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Review Open Access

Microbiome‑based diagnostic biomarkers in pancreatic ductal adenocarcinoma: Current evidence and translational challenges (Review)

Huiya Jin, Hui Sun, Jing Yang
Article Number: 478
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Long non-coding RNA CCAT2 functions as an oncogene in hepatocellular carcinoma, regulating cellular proliferation, migration and apoptosis

Ning Zhou, Zhongzhou Si, Ting Li, Guangshun Chen, Zhongqiang Zhang, Haizhi Qi
Article Number: 477
Published online on: 26 August 2026

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Article Open Access

Efficacy and safety of ICI‑based triple combination therapy for gene‑negative advanced lung adenocarcinoma

Diwei Mo, Huan Chen, Zhihong Zhu, Jinghua Yu, Xia Yang, Yiyu Lu, Keng Wang, Guifeng Xu, Luwen Lei, Xingxi Pan
Article Number: 476
Published online on: 25 August 2026

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Correction Open Access

[Corrigendum] Angiotensin II type 2 receptor‑interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal‑regulated kinase‑Snai2 pathway

Tingting Zhao, Qianting He, Zhonghua Liu, Xueqiang Ding, Xiaofeng Zhou, Anxun Wang
Article Number: 475
Published online on: 24 August 2026

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Article Open Access

Pazopanib treatment for primary cardiovascular sarcoma: A retrospective observational study and literature review

Shintaro Yamanaka, Yoshihiro Yakushijin, Shinji Hasebe, Shoichiro Yamamoto, Tomomi Fujii, Riko Kitazawa, Taketsugu Fujibuchi, Teruki Kidani, Masaki Maruta
Article Number: 474
Published online on: 21 August 2026

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Case Report Open Access

Primary cutaneous angiosarcoma of the scalp initially misdiagnosed as cellulitis in a 95‑year‑old Asian man: A case report

Baopeng Qi, Qianru Li, Yuan Gao, Yuanyu Tang, Yang Yu
Article Number: 473
Published online on: 21 August 2026

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Article Open Access

Colorectal cancer and tumor vaccines (Review)

Jianshuang Ma, Congming Xiang, Dong Xia
Article Number: 472
Published online on: 21 August 2026

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Article Open Access

Pre‑radiotherapy modified prognostic nutritional index predicts acute radiation enteritis in patients with cervical cancer undergoing radiotherapy: A retrospective study

Yani Zou, Rui Huang, Wenqiang Qin, Chunqiu Wu, Wei Zhang
Article Number: 471
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

Lumin Wang, Jiayi Yao, Hongfei Sun, Kang He, Dongdong Tong, Tusheng Song, Chen Huang
Article Number: 470
Published online on: 20 August 2026

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Article Open Access

Boost delivery in hypofractionated breast cancer radiotherapy: A registry‑based analysis of treatment patterns and survival

Karoline Elisabeth Horry, Dirk Vordermark, Daniel Medenwald, Jörg Andreas Müller
Article Number: 469
Published online on: 18 August 2026

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Article

Effect of perioperative nutritional status, inflammatory response and postoperative chemotherapy on survival after gastrectomy for advanced gastric cancer

Yoshinori Fujiwara, Shunji Endo, Masaharu Higashida, Masaaki Hori, Yoko Endo, Ryoko Makieda, Akihide Fujii, Miyoko Kobayashi, Kazuhiko Yoshimatsu, Tomio Ueno
Article Number: 468
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma

Yuexiang Niu, Gongen Tang
Article Number: 467
Published online on: 17 August 2026

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Article

OLFML2A expression in acute myeloid leukemia, with exploratory findings in acute lymphoblastic leukemia: Prognostic significance and re‑analysis of public single‑cell transcriptomic data

Xuan Lu, Jinlian Li, Xinru Zhao, Wanchuan Zhuang, Xingxing Chai
Article Number: 466
Published online on: 17 August 2026

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Article Open Access

Identifying an appropriate endogenous control for real‑time PCR of microRNAs in colorectal liver metastases: A comparison of 18s rRNA and small nuclear RNA RNU6B

Clemens Franz, Sibylle Hartmann, Alexis Ulrich, Georgios Polychronidis, Christoph Kahlert, Fee Klupp, Mohammed Al‑Saeedi
Article Number: 465
Published online on: 17 August 2026

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Article Open Access

Analysis of DNA methylation markers for diagnosing cervical precancer and cancer: A single‑center cross‑sectional study

Xue Chen, Jialing Li, Li Tian, Xinshu Li, Jingwen Guo, Liling He, Shulian Mao, Xitang Yang, Hua Guo
Article Number: 464
Published online on: 17 August 2026

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Article Open Access

Flavokawain A inhibits high glucose‑induced malignant progression of lung cancer cells by suppressing PRMT5‑mediated PTEN neddylation and nuclear translocation

Lei Zheng, Juan Li, Chao Song, Leping Shi, Qian Zhou, Yuyao Guan
Article Number: 463
Published online on: 14 August 2026

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Review Open Access

Metabolic heterogeneity and functional diversity of cancer-associated fibroblasts in gastric cancer (Review)

Qilu Fang, Neng Lv, Shuwei Yu, Jia Wang, Wenxiu Xin
Article Number: 462
Published online on: 14 August 2026

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Article Open Access

Preoperative CA125 and metabolic factors associated with high‑risk pathology in endometrial cancer

Yinuo Wang, Yueqi Yan, Wen Sun, Yiting Gao, Bingli Qi, Xia Li, Shouze Liu, Shikai Liu
Article Number: 461
Published online on: 14 August 2026

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Article Open Access

EGR1 regulates IGF‑1‑stimulated pancreatic cancer cell invasion by increasing IL‑11 expression 

Yena Choi, Euitaek Jung, Junekyu Han, Soon Young Shin
Article Number: 460
Published online on: 13 August 2026

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Review Open Access

Claudin‑18.2: Molecular mechanisms to clinical translation in solid tumors (Review)

Minjie Zhang, Dawei Wu, Yu Tang, Ning Li, Xinhua Yan
Article Number: 459
Published online on: 12 August 2026

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Case Report Open Access

Probable cavernous sinus‑adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang
Article Number: 458
Published online on: 12 August 2026

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Case Report Open Access

Immunotherapy combined with anti‑angiogenic therapy, radiotherapy and chemotherapy for the treatment of giant pelvic osteosarcoma: A case report and literature review

Qingying Yan, Jiewen Yang, Yunxia Liu, Miao Cheng, Zhen Wang, Jialu Chen, Yefeng Xu
Article Number: 457
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway

Hai-Jun Li, Jun-Ke Fu, Xiang-Ming Che, Lin Fan, Yong Zhang, E Bai
Article Number: 456
Published online on: 12 August 2026

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Article Open Access

Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells

Meng Zhang, Xiaoxue Zhang, Qian Rou, Ying Liu, Ailifeire Abudujiapaer, Minghui Li, Huaixiong Wang, Fang Cheng
Article Number: 455
Published online on: 12 August 2026

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Retraction Open Access

[Retracted] 2’,4’‑dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC‑3 human prostate cancer cell growth by induction of apoptosis 

Yuqing Sheng, Mingchang Zou, Yan Wang, Qiheng Li
Article Number: 454
Published online on: 11 August 2026

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Case Report Open Access

Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report

Liwei Zhao, Jiaguo Huang, Zhanwen Dong, Ji Sun, Runmiao Hua, Xuliang Wang, Kai Wang
Article Number: 453
Published online on: 10 August 2026

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Case Report Open Access

Primary leiomyosarcoma of the lumbar soft tissue treated with multimodal therapy, including anlotinib: A case report

Jia-Huan Li, De-Xiang Liao, Zhen Hu, Zhi-Yong Zhang, Dan-Dan Ma, Wei-Dong Jin, Tao Fu
Article Number: 452
Published online on: 10 August 2026

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Expression of Concern Open Access

[Expression of Concern] Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Article Number: 451
Published online on: 07 August 2026

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Article Open Access

Prognostic value of the CONUT score in newly diagnosed diffuse large B‑cell lymphoma

Sema Seçilmiş, Hacer Berna Afacan Öztürk, Birgül Ay Karakuş, Asena Dikyar, Kadir Acar, Ahmet Kürşad Güneş
Article Number: 450
Published online on: 06 August 2026

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Article Open Access

DHX15 as a novel immune‑related prognostic biomarker in breast cancer: An integrated bioinformatics analysis with in vitro functional validation

Fan Li, Qin Yue, Jing Li
Article Number: 449
Published online on: 05 August 2026

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Case Report Open Access

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK‑positive metastatic non‑small cell lung cancer: A case report

Alizée Simon, Gautier Treffel, Guillaume Pax, Guillaume Gauchotte, Marie Husson, Idrissia Hanriot, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Article Number: 448
Published online on: 05 August 2026

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Expression of Concern Open Access

[Expression of Concern] Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation  

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 447
Published online on: 05 August 2026

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Article

Preliminary study on the efficacy of pazopanib combined with toripalimab as first‑line therapy for metastatic renal cell carcinoma: Real‑world data from a single center

Bin Wang, Tianjun Xing, Hongyu Liu, Xuebing Han, Kai Wu
Article Number: 446
Published online on: 05 August 2026

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Review Open Access

Subtype‑specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review)

Yidan Ran
Article Number: 445
Published online on: 04 August 2026

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Review Open Access

Chrono‑immunotherapy in genitourinary oncology: From emerging evidence to clinical translation (Review)

Osama Zein Deen, Xin Ye, Patsy Lee, Roxana Astani, Georg Bjarnason, Christian Kollmannsberger, Bernhard Eigl, Guliz Ozgun
Article Number: 444
Published online on: 03 August 2026

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Case Report Open Access

Imaging features and clinical management of mesenteric cavernous lymphangioma: A case report and literature review

Zhongze Zhao, Ermin Cai, Tong Zhou, Jianju Feng, Lingzhi Gu
Article Number: 443
Published online on: 03 August 2026

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Article Open Access

Association between the expression of GSTP1 and mutant p53, poor chemotherapy response and metastasis in patients with osteosarcoma

Bangkit Primayudha, Evelina Kodrat, Yogi Prabowo, Aryadi Kurniawan, Nurjati Chairani Siregar, Muhamad Naseh Sajadi Budi Irawan, Rahadyan Magetsari, I Gede Eka Wiratnaya, Istan Irmansyah Irsan, Achmad Fauzi Kamal
Article Number: 442
Published online on: 03 August 2026

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Article Open Access

Astragaloside IV suppresses triple‑negative breast cancer cell migration and invasion by targeting BCAT1‑mediated branched‑chain amino acid metabolism

Yi-Ting Liu, Lu Zhang, Xiao-Dong Sun
Article Number: 441
Published online on: 03 August 2026

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Article Open Access

LC‑MS/MS‑based clinical value exploration of the methionine cycle in luminal breast cancer

Wenxuan Wu, Yifeng Tu, Han Yao, Yajun Mao, Changfei Mao, Feifei Xu, Zhongcheng Wang
Article Number: 440
Published online on: 03 August 2026

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Article

Accuracy of percutaneous ultrasound‑guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease

Camilla Mazzoni, Lisa Argnani, Davide Di Benedetto, Sofia Maria Bakken, Beatrice Casadei, Cinzia Pellegrini, Leonardo De Marco, Marta Machado, Alessandro Broccoli, Pier Luigi Zinzani, Carla Serra
Article Number: 439
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA‑miRNA‑mRNA ceRNA networks

Qian Xu, Xiyun Jia, Qian Wu, Lei Shi, Zihan Ma, Nan Ba, Han Zhao, Xingzhou Xia, Zisen Zhang
Article Number: 438
Published online on: 03 August 2026

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Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Review Open Access

Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Article Open Access

Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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Article Open Access

A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Case Report Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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