Journal Articles

Epigenetic regulation and cancer (Review)

Q. W. Chen, X. Y. Zhu, Y. Y. Li, Z. Q. Meng

Pages: 523-532 Published online on: 11 December 2013

Wnt1 inducible signalling pathway protein-2 (WISP‑2/CCN5): Roles and regulation in human cancers (Review)

Jiafu Ji, Shuqin Jia, Ke Ji, Wen G. Jiang

Pages: 533-539 Published online on: 09 December 2013
Open Access

Connexin-dependent gap junction enhancement is involved in the synergistic effect of sorafenib and all-trans retinoic acid on HCC growth inhibition

Yan Yang, Shu-Kui Qin, Qiong Wu, Zi-Shu Wang, Rong-Sheng Zheng, Xu-Hui Tong, Hao Liu, Liang Tao, Xian-Di He

Pages: 540-550 Published online on: 05 December 2013
Open Access

Natural and glucosyl flavonoids inhibit poly(ADP-ribose) polymerase activity and induce synthetic lethality in BRCA mutant cells

Junko Maeda, Erica J. Roybal, Colleen A. Brents, Mitsuru Uesaka, Yasushi Aizawa, Takamitsu A. Kato

Pages: 551-556 Published online on: 05 December 2013
Open Access

Bioinformatic analysis of the membrane cofactor protein CD46 and microRNA expression in hepatocellular carcinoma

Zejun Lu, Chuanfu Zhang, Jiajun Cui, Qi Song, Ligui Wang, Jingbo Kang, Peng Li, Xiaofeng Hu, Hongbin Song, Jinliang Yang, Yansong Sun

Pages: 557-564 Published online on: 28 November 2013
Open Access

Proposal for a new mediastinal compartment classification of transverse plane images according to the Japanese Association for Research on the Thymus (JART) General Rules for the Study of Mediastinal Tumors

Kiminori Fujimoto, Masaki Hara, Noriyuki Tomiyama, Masahiko Kusumoto, Fumikazu Sakai, Yoshitaka Fujii

Pages: 565-572 Published online on: 06 December 2013
Open Access

Active form of AKT controls cell proliferation and response to apoptosis in hepatocellular carcinoma

Imge Kunter, Esra Erdal, Deniz Nart, Funda Yilmaz, Sedat Karademir, Ozgul Sagol, Nese Atabey

Pages: 573-580 Published online on: 16 December 2013
Open Access

Capsaicin induces apoptosis in PC12 cells through ER stress

Olga Krizanova, Iveta Steliarova, Lucia Csaderova, Michal Pastorek, Sona Hudecova

Pages: 581-588 Published online on: 13 December 2013

Mesenchymal phenotype after chemotherapy is associated with chemoresistance and poor clinical outcome in esophageal cancer

Johji Hara, Hiroshi Miyata, Makoto Yamasaki, Keijiro Sugimura, Tsuyoshi Takahashi, Yukinori Kurokawa, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki

Pages: 589-596 Published online on: 28 November 2013

Hepatocyte growth factor and HER2/neu downregulate expression of apoptosis-inducing factor in non-small cell lung cancer

Yung-Yen Chiang, Kuan-Chih Chow, Tze-Yi Lin, I-Ping Chiang, Hsing-Yuan Fang

Pages: 597-604 Published online on: 25 November 2013

Prognostic significance of IL-17 mRNA expression in peritoneal lavage in gastric cancer patients who underwent curative resection

Takeshi Iida, Makoto Iwahashi, Masahiro Katsuda, Koichiro Ishida, Mikihito Nakamori, Masaki Nakamura, Teiji Naka, Toshiyasu Ojima, Kentaro Ueda, Keiji Hayata, Hironao Yasuoka, Hiroki Yamaue

Pages: 605-612 Published online on: 10 December 2013

Relapse-associated microRNA in gastric cancer patients after S-1 adjuvant chemotherapy

Tetsuya Omura, Yutaka Shimada, Takuya Nagata, Tomoyuki Okumura, Junya Fukuoka, Fuminori Yamagishi, Sadakatsu Tajika, Sanae Nakajima, Atsushi Kawabe, Kazuhiro Tsukada

Pages: 613-618 Published online on: 05 December 2013

The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway

Takashi Ui, Kazue Morishima, Shin Saito, Yuji Sakuma, Hirofumi Fujii, Yoshinori Hosoya, Shumpei Ishikawa, Hiroyuki Aburatani, Masashi Fukayama, Toshiro Niki, Yoshikazu Yasuda

Pages: 619-624 Published online on: 05 December 2013

(-)-Epigallocatechin-3-gallate suppresses liver metastasis of human colorectal cancer

Takehito Maruyama, Soichiro Murata, Ken Nakayama, Naoki Sano, Koichi Ogawa, Takeshi Nowatari, Takafumi Tamura, Reiji Nozaki, Kiyoshi Fukunaga, Nobuhiro Ohkohchi

Pages: 625-633 Published online on: 13 December 2013

Mina53, a novel molecular marker for the diagnosis and prognosis of gastric adenocarcinoma

Jing Xing, Ke Wang, Peng-Wei Liu, Qi Miao, Xiao-Yu Chen

Pages: 634-640 Published online on: 12 December 2013

Activated hepatic stellate cells promote hepatocellular carcinoma cell migration and invasion via the activation of FAK-MMP9 signaling

Shaoshan Han, Lei Han, Yingmin Yao, Hao Sun, Xianfeng Zan, Qingguang Liu

Pages: 641-648 Published online on: 27 November 2013

AZD8055 induces cell death associated with autophagy and activation of AMPK in hepatocellular carcinoma

Min Hu, Haili Huang, Rui Zhao, Peng Li, Mingyi Li, Huilai Miao, Nianping Chen, Ming Chen

Pages: 649-656 Published online on: 02 December 2013

Establishment of a green fluorescent protein tracing murine model focused on the functions of host components in necrosis repair and the niche of subcutaneously implanted glioma

Zhao-Hui Lu, Ke Lv, Jin-Shi Zhang, Chun-Gang Dai, Bin Liu, Xiao-Yu Ma, Lin-Ming He, Jing-Yun Jia, Yan-Ming Chen, Xing-Liang Dai, Ai-Dong Wang, Jun Dong, Quan-Bin Zhang, Qing Lan, Qiang Huang

Pages: 657-664 Published online on: 27 November 2013

Clinical significance of TrkB expression in nasopharyngeal carcinoma

Shi-Sheng Li, Jia-Jia Liu, Shuang Wang, Qing-Lai Tang, Bing-Bing Liu, Xin-Ming Yang

Pages: 665-672 Published online on: 28 November 2013

Genistein attenuates cancer stem cell characteristics in gastric cancer through the downregulation of Gli1

Dayeon Yu, Hyun-Soo Shin, Yeo Song Lee, Doyeon Lee, Shin Kim, Yong Chan Lee

Pages: 673-678 Published online on: 02 December 2013

Expression of tissue factor signaling pathway elements correlates with the production of vascular endothelial growth factor and interleukin-8 in human astrocytoma patients

Tatiana C. Carneiro-Lobo, Marina T. Lima, Andréa Mariano‑Oliveira, Angélica Dutra‑Oliveira, Sueli M. Oba-Shinjo, Suely K.N. Marie, Mari C. Sogayar, Robson Q. Monteiro

Pages: 679-686 Published online on: 28 November 2013

Identification of natural splice variants of SAMHD1 in virus-infected HCC

Yunpeng Shi, Guoyue Lv, Zhe Chu, Liling Piao, Xingkai Liu, Tuo Wang, Yanfang Jiang, Ping Zhang

Pages: 687-692 Published online on: 05 December 2013

Reduced expression of DENND2D through promoter hypermethylation is an adverse prognostic factor in squamous cell carcinoma of the esophagus

Soki Hibino, Mitsuro Kanda, Hisaharu Oya, Hideki Takami, Dai Shimizu, Shuji Nomoto, Mitsuhiro Hishida, Yukiko Niwa, Masahiko Koike, Suguru Yamada, Yoko Nishikawa, Mikako Asai, Goro Nakayama, Tsutomu Fujii, Hiroyuki Sugimoto, Michitaka Fujiwara, Yasuhiro Kodera

Pages: 693-700 Published online on: 05 December 2013

Molecular mechanisms of [18F]fluorodeoxyglucose accumulation in liver cancer

Kunihiko Izuishi, Yuka Yamamoto, Hirohito Mori, Riko Kameyama, Shintaro Fujihara, Tsutomu Masaki, Yasuyuki Suzuki

Pages: 701-706 Published online on: 29 November 2013

Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells

Yonghua Xu, Yong An, Xuehao Wang, Wenzhang Zha, Xiangcheng Li

Pages: 707-712 Published online on: 28 November 2013

Novel EXT1 mutation identified in a pedigree with hereditary multiple exostoses

Li Cao, Fei Liu, Mingxiang Kong, Yong Fang, Haifeng Gu, Yu Chen, Chen Zhao, Shuijun Zhang, Qing Bi

Pages: 713-718 Published online on: 02 December 2013

Factors involved in the cisplatin resistance of KCP‑4 human epidermoid carcinoma cells

Shigeru Oiso, Yui Takayama, Rie Nakazaki, Naoko Matsunaga, Chie Motooka, Asuka Yamamura, Ryuji Ikeda, Kazuo Nakamura, Yasuo Takeda, Hiroko Kariyazono

Pages: 719-726 Published online on: 05 December 2013

Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell-like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie

Pages: 727-736 Published online on: 13 December 2013

Distinct roles of Akt1 in regulating proliferation, migration and invasion in HepG2 and HCT 116 cells

Liang Chen, Qiao-Hui Kang, Ying Chen, Ya-Hong Zhang, Qian Li, Song-Qiang Xie, Chao-Jie Wang

Pages: 737-744 Published online on: 28 November 2013

Upregulation of NEK2 is associated with drug resistance in ovarian cancer

Xia Liu, Yutao Gao, Yi Lu, Jian Zhang, Li Li, Fuqiang Yin

Pages: 745-754 Published online on: 09 December 2013

Licochalcone A induces apoptosis in KB human oral cancer cells via a caspase-dependent FasL signaling pathway

Jae-Sung Kim, Mi-Ra Park, Sook-Young Lee, Do Kyoung Kim, Sung‑Min Moon, Chun Sung Kim, Seung Sik Cho, Goo Yoon, Hee-Jeong Im, Jae‑Seek You, Ji-Su Oh, Su-Gwan Kim

Pages: 755-762 Published online on: 16 December 2013

Pien Tze Huang induces apoptosis in multidrug‑resistant U2OS/ADM cells via downregulation of Bcl‑2, survivin and P-gp and upregulation of Bax

Yan Zhang, Qihong Wang, Susheng Niu, Junning Liu, Li Zhang

Pages: 763-770 Published online on: 12 December 2013

Therapeutic potential of sepantronium bromide YM155 in gemcitabine-resistant human urothelial carcinoma cells

Yen Ta Huang, Chuan Chu Cheng, Tzu Chun Lin, Ted H. Chiu, Pei Chun Lai

Pages: 771-780 Published online on: 28 November 2013

A preliminary study on the construction of double suicide gene delivery vectors by mesenchymal stem cells and the in vitro inhibitory effects on SKOV3 cells

Jingyan Jiang, Dee Wei, Li Sun, Yuxia Wang, Xihai Wu, Ying Li, Zhenghui Fang, Hui Shang, Zengtao Wei

Pages: 781-787 Published online on: 05 December 2013

Expression of early growth response-1 in colorectal cancer and its relation to tumor cell proliferation and apoptosis

Dae-Seong Myung, Young-Lan Park, Nuri Kim, Cho-Yun Chung, Hyung-Chul Park, Jong-Sun Kim, Sung-Bum Cho, Wan-Sik Lee, Jae-Hyuk Lee, Young-Eun Joo

Pages: 788-794 Published online on: 29 November 2013

Impact of stereotactic body radiotherapy on colorectal cancer with distant metastases

Masayuki Hiraki, Junichi Nishimura, Masahisa Ohtsuka, Hiroya Shiomi, Mamoru Uemura, Naotsugu Haraguchi, Taishi Hata, Taro Hayashi, Ichiro Takemasa, Tsunekazu Mizushima, Fumiaki Isohashi, Yasuo Yoshioka, Kazuhiko Ogawa, Yuichiro Doki, Masaki Mori, Hirofumi Yamamoto

Pages: 795-799 Published online on: 27 November 2013

The CCL5/CCR5 axis contributes to the perineural invasion of human salivary adenoid cystic carcinoma

Zhiyuan Shen, Tianyi Li, Da Chen, Sen Jia, Xiangming Yang, Liang Liang, Juan Chai, Xiaobing Cheng, Xinjie Yang, Moyi Sun

Pages: 800-806 Published online on: 13 December 2013

Rearrangements of chromosome bands 15q12-q21 are secondary to HMGA2 deregulation in conventional lipoma

Gemma Macchia, Karolin H. Nord, Giuseppina D'Alessandro, Jenny Nilsson, Linda Magnusson, Nils Mandahl, Clelia Tiziana Storlazzi, Fredrik Mertens

Pages: 807-811 Published online on: 02 December 2013

Knockdown of Slit2 promotes growth and motility in gastric cancer cells via activation of AKT/β-catenin

Rongliang Shi, Zhen Yang, Weiyan Liu, Bingya Liu, Ziping Xu, Ziping Zhang

Pages: 812-818 Published online on: 02 December 2013

Inhibition of CD73 stimulates the migration and invasion of B16F10 melanoma cells in vitro, but results in impaired angiogenesis and reduced melanoma growth in vivo

Patrycja Koszałka, Anna Pryszlak, Monika Gołuńska, Justyna Kolasa, Grzegorz Stasiłojć, Andrzej C. Składanowski, Jacek J. Bigda

Pages: 819-827 Published online on: 29 November 2013

Allograft inflammatory factor-1 is an independent prognostic indicator that regulates β-catenin in gastric cancer

Yang Ye, Shuhan Miao, Rongzhu Lu, Xiaowei Xia, Yansu Chen, Jianbing Zhang, Xuming Wu, Song He, Fulin Qiang, Jianwei Zhou

Pages: 828-834 Published online on: 12 December 2013

Inhibition of IL-6 expression in LNCaP prostate cancer cells by a combination of atorvastatin and celecoxib

Huaqian Wang, Xiao-Xing Cui, Susan Goodin, Ning Ding, Jeremiah Van Doren, Zhiyun Du, Mou-Tuan Huang, Yue Liu, Xiaodong Cheng, Robert S. Dipaola, Allan H. Conney, Xi Zheng

Pages: 835-841 Published online on: 29 November 2013

Voltage-gated and ATP-sensitive K+ channels are associated with cell proliferation and tumorigenesis of human glioma

Qin Ru, Xiang Tian, Yu-Xiang Wu, Ri-Hui Wu, Ming-Shan Pi, Chao-Ying Li

Pages: 842-848 Published online on: 27 November 2013

Pseudolaric acid B induces caspase-dependent cell death in human ovarian cancer cells

Bo Yu, Dong-Mei Yue, Lin-Hua Shu, Nai-Jing Li, Jia-He Wang

Pages: 849-857 Published online on: 25 November 2013

β-elemene, a compound derived from Rhizoma zedoariae, reverses multidrug resistance mediated by the ABCB1 transporter

Hui-Qin Guo, Guan-Nan Zhang, Yi-Jun Wang, Yun-Kai Zhang, Kamlesh Sodani, Tanaji T. Talele, Charles R. Ashby, Zhe-Sheng Chen

Pages: 858-866 Published online on: 27 November 2013

Silencing Dicer expression enhances cellular proliferative and invasive capacities in human tongue squamous cell carcinoma

Shuguang Zeng, Jing Yang, Jianjiang Zhao, Qicai Liu, Mingdeng Rong, Zehong Guo, Wenfeng Gao

Pages: 867-873 Published online on: 06 December 2013

Cells susceptible to epithelial-mesenchymal transition are enriched in stem-like side population cells from prostate cancer

Yong Luo, Xinhao Cui, Jiahui Zhao, Yili Han, Mingchuan Li, Yunhua Lin, Yongguang Jiang, Ling Lan

Pages: 874-884 Published online on: 06 December 2013

Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis

Lufang Chen, Xiaodong Lu, Tiantian Zeng, Yuanyuan Chen, Qian Chen, Weijiang Wu, Xun Yan, Honghua Cai, Zhijian Zhang, Qixiang Shao, Wenxin Qin

Pages: 885-893 Published online on: 06 December 2013

Phosphoglycerate kinase 1 promotes radioresistance in U251 human glioma cells

Hao Ding, Yi-Jun Cheng, Hua Yan, Rui Zhang, Jin-Bing Zhao, Chun-Fa Qian, Wen-Bin Zhang, Hong Xiao, Hong-Yi Liu

Pages: 894-900 Published online on: 27 November 2013

APE1/Ref-1 enhances DNA binding activity of mutant p53 in a redox-dependent manner

Yanping Cun, Nan Dai, Mengxia Li, Chengjie Xiong, Qinhong Zhang, Jiangdong Sui, Chengyuan Qian, Dong Wang

Pages: 901-909 Published online on: 02 December 2013

miR-200b suppresses cell proliferation, migration and enhances chemosensitivity in prostate cancer by regulating Bmi-1

Junjie Yu, Youyi Lu, Di Cui, Enhui Li, Yipin Zhu, Yuyang Zhao, Fujun Zhao, Shujie Xia

Pages: 910-918 Published online on: 05 December 2013

Ginsenoside Rg3 induces DNA damage in human osteosarcoma cells and reduces MNNG-induced DNA damage and apoptosis in normal human cells

Yue-Hui Zhang, Hai-Dong Li, Bo Li, Sheng-Dan Jiang, Lei-Sheng Jiang

Pages: 919-925 Published online on: 11 December 2013

Investigation of the mechanism involved in the As2O3-regulated decrease in MDR1 expression in leukemia cells

Feng Gao, Jia Liu, Wan Wei Dong, Wei Wang, Ying Wang, Dali Cai, Zhihong Zheng, Kailai Sun

Pages: 926-932 Published online on: 16 December 2013

Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma

Qian Sun, Ronghua Wang, Yan Wang, Jing Luo, Peng Wang, Bin Cheng

Pages: 933-939 Published online on: 12 December 2013

Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe

Maria Raffaella Greco, Ester Antelmi, Giovanni Busco, Lorenzo Guerra, Rosa Rubino, Valeria Casavola, Stephan Joel Reshkin, Rosa Angela Cardone

Pages: 940-946 Published online on: 13 December 2013

Peroxisome proliferator-activated receptor γ ligand troglitazone and TRAIL synergistically induce apoptosis

Makoto Koyama, Yoshihiro Sowa, Mano Horinaka, Ahmed E. Goda, Jun Fujiwara, Toshiyuki Sakai

Pages: 947-954 Published online on: 25 November 2013

In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma

Michel Pinheiro Dos Santos, Caroline Brunetto de Farias, Rafael Roesler, Algemir Lunardi Brunetto, Ana Lucia Abujamra

Pages: 955-968 Published online on: 06 December 2013

Levels of cell-free DNA and plasma KRAS during treatment of advanced NSCLC

Anneli Dowler Nygaard, Karen-Lise Garm Spindler, Niels Pallisgaard, Rikke Fredslund Andersen, Anders Jakobsen

Pages: 969-974 Published online on: 06 December 2013

Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53- and caspase-dependent induction of p38 MAPK

He-Qi Bu, Dian-Lei Liu, Wei-Tian Wei, Liang Chen, Hai Huang, Ye Li, Jun-Hui Cui

Pages: 975-982 Published online on: 02 December 2013

Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells

Shigeki Nakagawa, Yasuo Sakamoto, Hirohisa Okabe, Hiromitsu Hayashi, Daisuke Hashimoto, Naomi Yokoyama, Ryuma Tokunaga, Keita Sakamoto, Hideyuki Kuroki, Kosuke Mima, Toru Beppu, Hideo Baba

Pages: 983-988 Published online on: 13 December 2013

Bone morphogenetic protein 9 regulates tumor growth of osteosarcoma cells through the Wnt/β-catenin pathway

Zilan Lv, Chuan Wang, Taixian Yuan, Yuehong Liu, Tao Song, Yueliang Liu, Chu Chen, Min Yang, Zuchuan Tang, Qiong Shi, Yaguang Weng

Pages: 989-994 Published online on: 16 December 2013

Polymorphisms of the pri-miR-34b/c promoter and TP53 codon 72 are associated with risk of colorectal cancer

Jisu Oh, Jong Woo Kim, Bo Eun Lee, Moon Ju Jang, So Young Chong, Pil Won Park, Seong Gyu Hwang, Doyeun Oh, Nam Keun Kim

Pages: 995-1002 Published online on: 13 December 2013

A multimarker qPCR platform for the characterisation of endometrial cancer

Anna Supernat, Sylwia Łapińska-Szumczyk, Hanna Majewska, Jacek Gulczyński, Wojciech Biernat, Dariusz Wydra, Anna J. Żaczek

Pages: 1003-1013 Published online on: 13 December 2013

Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer

Semra Demokan, Alice Y. Chuang, Kavita M. Pattani, David Sidransky, Wayne Koch, Joseph A. Califano

Pages: 1014-1020 Published online on: 16 December 2013

Suppression of VEGF expression through interruption of the HIF‑1α and Akt signaling cascade modulates the anti‑angiogenic activity of DAPK in ovarian carcinoma cells

Sung Taek Park, Boh-Ram Kim, Sung Ho Park, Jeong Heon Lee, Eun-Ju Lee, Seung-Hoon Lee, Seung Bae Rho

Pages: 1021-1029 Published online on: 16 December 2013
Open Access

[Erratum] Expression of junB is markedly stimulated by glycyrrhizin in a human hepatoma cell line

Katsuro Koike

Pages: 1030-1030 Published online on: 10 December 2013
Journal Cover

2014-February
Volume 31 Issue 2

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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