Journal Articles
Review
Epigenetic regulation and cancer (Review)
Q. W. Chen, X. Y. Zhu, Y. Y. Li, Z. Q. Meng
Pages: 523-532 Published online on: 11 December 2013
Review
Wnt1 inducible signalling pathway protein-2 (WISP‑2/CCN5): Roles and regulation in human cancers (Review)
Jiafu Ji, Shuqin Jia, Ke Ji, Wen G. Jiang
Pages: 533-539 Published online on: 09 December 2013
Article
Connexin-dependent gap junction enhancement is involved in the synergistic effect of sorafenib and all-trans retinoic acid on HCC growth inhibition
Yan Yang, Shu-Kui Qin, Qiong Wu, Zi-Shu Wang, Rong-Sheng Zheng, Xu-Hui Tong, Hao Liu, Liang Tao, Xian-Di He
Pages: 540-550 Published online on: 05 December 2013
Article
Natural and glucosyl flavonoids inhibit poly(ADP-ribose) polymerase activity and induce synthetic lethality in BRCA mutant cells
Junko Maeda, Erica J. Roybal, Colleen A. Brents, Mitsuru Uesaka, Yasushi Aizawa, Takamitsu A. Kato
Pages: 551-556 Published online on: 05 December 2013
Article
Bioinformatic analysis of the membrane cofactor protein CD46 and microRNA expression in hepatocellular carcinoma
Zejun Lu, Chuanfu Zhang, Jiajun Cui, Qi Song, Ligui Wang, Jingbo Kang, Peng Li, Xiaofeng Hu, Hongbin Song, Jinliang Yang, Yansong Sun
Pages: 557-564 Published online on: 28 November 2013
Article
Proposal for a new mediastinal compartment classification of transverse plane images according to the Japanese Association for Research on the Thymus (JART) General Rules for the Study of Mediastinal Tumors
Kiminori Fujimoto, Masaki Hara, Noriyuki Tomiyama, Masahiko Kusumoto, Fumikazu Sakai, Yoshitaka Fujii
Pages: 565-572 Published online on: 06 December 2013
Article
Active form of AKT controls cell proliferation and response to apoptosis in hepatocellular carcinoma
Imge Kunter, Esra Erdal, Deniz Nart, Funda Yilmaz, Sedat Karademir, Ozgul Sagol, Nese Atabey
Pages: 573-580 Published online on: 16 December 2013
Article
Capsaicin induces apoptosis in PC12 cells through ER stress
Olga Krizanova, Iveta Steliarova, Lucia Csaderova, Michal Pastorek, Sona Hudecova
Pages: 581-588 Published online on: 13 December 2013
Article
Mesenchymal phenotype after chemotherapy is associated with chemoresistance and poor clinical outcome in esophageal cancer
Johji Hara, Hiroshi Miyata, Makoto Yamasaki, Keijiro Sugimura, Tsuyoshi Takahashi, Yukinori Kurokawa, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
Pages: 589-596 Published online on: 28 November 2013
Article
Hepatocyte growth factor and HER2/neu downregulate expression of apoptosis-inducing factor in non-small cell lung cancer
Yung-Yen Chiang, Kuan-Chih Chow, Tze-Yi Lin, I-Ping Chiang, Hsing-Yuan Fang
Pages: 597-604 Published online on: 25 November 2013
Article
Prognostic significance of IL-17 mRNA expression in peritoneal lavage in gastric cancer patients who underwent curative resection
Takeshi Iida, Makoto Iwahashi, Masahiro Katsuda, Koichiro Ishida, Mikihito Nakamori, Masaki Nakamura, Teiji Naka, Toshiyasu Ojima, Kentaro Ueda, Keiji Hayata, Hironao Yasuoka, Hiroki Yamaue
Pages: 605-612 Published online on: 10 December 2013
Article
Relapse-associated microRNA in gastric cancer patients after S-1 adjuvant chemotherapy
Tetsuya Omura, Yutaka Shimada, Takuya Nagata, Tomoyuki Okumura, Junya Fukuoka, Fuminori Yamagishi, Sadakatsu Tajika, Sanae Nakajima, Atsushi Kawabe, Kazuhiro Tsukada
Pages: 613-618 Published online on: 05 December 2013
Article
The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway
Takashi Ui, Kazue Morishima, Shin Saito, Yuji Sakuma, Hirofumi Fujii, Yoshinori Hosoya, Shumpei Ishikawa, Hiroyuki Aburatani, Masashi Fukayama, Toshiro Niki, Yoshikazu Yasuda
Pages: 619-624 Published online on: 05 December 2013
Article
(-)-Epigallocatechin-3-gallate suppresses liver metastasis of human colorectal cancer
Takehito Maruyama, Soichiro Murata, Ken Nakayama, Naoki Sano, Koichi Ogawa, Takeshi Nowatari, Takafumi Tamura, Reiji Nozaki, Kiyoshi Fukunaga, Nobuhiro Ohkohchi
Pages: 625-633 Published online on: 13 December 2013
Article
Mina53, a novel molecular marker for the diagnosis and prognosis of gastric adenocarcinoma
Jing Xing, Ke Wang, Peng-Wei Liu, Qi Miao, Xiao-Yu Chen
Pages: 634-640 Published online on: 12 December 2013
Article
Activated hepatic stellate cells promote hepatocellular carcinoma cell migration and invasion via the activation of FAK-MMP9 signaling
Shaoshan Han, Lei Han, Yingmin Yao, Hao Sun, Xianfeng Zan, Qingguang Liu
Pages: 641-648 Published online on: 27 November 2013
Article
AZD8055 induces cell death associated with autophagy and activation of AMPK in hepatocellular carcinoma
Min Hu, Haili Huang, Rui Zhao, Peng Li, Mingyi Li, Huilai Miao, Nianping Chen, Ming Chen
Pages: 649-656 Published online on: 02 December 2013
Article
Establishment of a green fluorescent protein tracing murine model focused on the functions of host components in necrosis repair and the niche of subcutaneously implanted glioma
Zhao-Hui Lu, Ke Lv, Jin-Shi Zhang, Chun-Gang Dai, Bin Liu, Xiao-Yu Ma, Lin-Ming He, Jing-Yun Jia, Yan-Ming Chen, Xing-Liang Dai, Ai-Dong Wang, Jun Dong, Quan-Bin Zhang, Qing Lan, Qiang Huang
Pages: 657-664 Published online on: 27 November 2013
Article
Clinical significance of TrkB expression in nasopharyngeal carcinoma
Shi-Sheng Li, Jia-Jia Liu, Shuang Wang, Qing-Lai Tang, Bing-Bing Liu, Xin-Ming Yang
Pages: 665-672 Published online on: 28 November 2013
Article
Genistein attenuates cancer stem cell characteristics in gastric cancer through the downregulation of Gli1
Dayeon Yu, Hyun-Soo Shin, Yeo Song Lee, Doyeon Lee, Shin Kim, Yong Chan Lee
Pages: 673-678 Published online on: 02 December 2013
Article
Expression of tissue factor signaling pathway elements correlates with the production of vascular endothelial growth factor and interleukin-8 in human astrocytoma patients
Tatiana C. Carneiro-Lobo, Marina T. Lima, Andréa Mariano‑Oliveira, Angélica Dutra‑Oliveira, Sueli M. Oba-Shinjo, Suely K.N. Marie, Mari C. Sogayar, Robson Q. Monteiro
Pages: 679-686 Published online on: 28 November 2013
Article
Identification of natural splice variants of SAMHD1 in virus-infected HCC
Yunpeng Shi, Guoyue Lv, Zhe Chu, Liling Piao, Xingkai Liu, Tuo Wang, Yanfang Jiang, Ping Zhang
Pages: 687-692 Published online on: 05 December 2013
Article
Reduced expression of DENND2D through promoter hypermethylation is an adverse prognostic factor in squamous cell carcinoma of the esophagus
Soki Hibino, Mitsuro Kanda, Hisaharu Oya, Hideki Takami, Dai Shimizu, Shuji Nomoto, Mitsuhiro Hishida, Yukiko Niwa, Masahiko Koike, Suguru Yamada, Yoko Nishikawa, Mikako Asai, Goro Nakayama, Tsutomu Fujii, Hiroyuki Sugimoto, Michitaka Fujiwara, Yasuhiro Kodera
Pages: 693-700 Published online on: 05 December 2013
Article
Molecular mechanisms of [18F]fluorodeoxyglucose accumulation in liver cancer
Kunihiko Izuishi, Yuka Yamamoto, Hirohito Mori, Riko Kameyama, Shintaro Fujihara, Tsutomu Masaki, Yasuyuki Suzuki
Pages: 701-706 Published online on: 29 November 2013
Article
Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells
Yonghua Xu, Yong An, Xuehao Wang, Wenzhang Zha, Xiangcheng Li
Pages: 707-712 Published online on: 28 November 2013
Article
Novel EXT1 mutation identified in a pedigree with hereditary multiple exostoses
Li Cao, Fei Liu, Mingxiang Kong, Yong Fang, Haifeng Gu, Yu Chen, Chen Zhao, Shuijun Zhang, Qing Bi
Pages: 713-718 Published online on: 02 December 2013
Article
Factors involved in the cisplatin resistance of KCP‑4 human epidermoid carcinoma cells
Shigeru Oiso, Yui Takayama, Rie Nakazaki, Naoko Matsunaga, Chie Motooka, Asuka Yamamura, Ryuji Ikeda, Kazuo Nakamura, Yasuo Takeda, Hiroko Kariyazono
Pages: 719-726 Published online on: 05 December 2013
Article
Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell-like side population cells
Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Pages: 727-736 Published online on: 13 December 2013
Article
Distinct roles of Akt1 in regulating proliferation, migration and invasion in HepG2 and HCT 116 cells
Liang Chen, Qiao-Hui Kang, Ying Chen, Ya-Hong Zhang, Qian Li, Song-Qiang Xie, Chao-Jie Wang
Pages: 737-744 Published online on: 28 November 2013
Article
Upregulation of NEK2 is associated with drug resistance in ovarian cancer
Xia Liu, Yutao Gao, Yi Lu, Jian Zhang, Li Li, Fuqiang Yin
Pages: 745-754 Published online on: 09 December 2013
Article
Licochalcone A induces apoptosis in KB human oral cancer cells via a caspase-dependent FasL signaling pathway
Jae-Sung Kim, Mi-Ra Park, Sook-Young Lee, Do Kyoung Kim, Sung‑Min Moon, Chun Sung Kim, Seung Sik Cho, Goo Yoon, Hee-Jeong Im, Jae‑Seek You, Ji-Su Oh, Su-Gwan Kim
Pages: 755-762 Published online on: 16 December 2013
Article
Pien Tze Huang induces apoptosis in multidrug‑resistant U2OS/ADM cells via downregulation of Bcl‑2, survivin and P-gp and upregulation of Bax
Yan Zhang, Qihong Wang, Susheng Niu, Junning Liu, Li Zhang
Pages: 763-770 Published online on: 12 December 2013
Article
Therapeutic potential of sepantronium bromide YM155 in gemcitabine-resistant human urothelial carcinoma cells
Yen Ta Huang, Chuan Chu Cheng, Tzu Chun Lin, Ted H. Chiu, Pei Chun Lai
Pages: 771-780 Published online on: 28 November 2013
Article
A preliminary study on the construction of double suicide gene delivery vectors by mesenchymal stem cells and the in vitro inhibitory effects on SKOV3 cells
Jingyan Jiang, Dee Wei, Li Sun, Yuxia Wang, Xihai Wu, Ying Li, Zhenghui Fang, Hui Shang, Zengtao Wei
Pages: 781-787 Published online on: 05 December 2013
Article
Expression of early growth response-1 in colorectal cancer and its relation to tumor cell proliferation and apoptosis
Dae-Seong Myung, Young-Lan Park, Nuri Kim, Cho-Yun Chung, Hyung-Chul Park, Jong-Sun Kim, Sung-Bum Cho, Wan-Sik Lee, Jae-Hyuk Lee, Young-Eun Joo
Pages: 788-794 Published online on: 29 November 2013
Article
Impact of stereotactic body radiotherapy on colorectal cancer with distant metastases
Masayuki Hiraki, Junichi Nishimura, Masahisa Ohtsuka, Hiroya Shiomi, Mamoru Uemura, Naotsugu Haraguchi, Taishi Hata, Taro Hayashi, Ichiro Takemasa, Tsunekazu Mizushima, Fumiaki Isohashi, Yasuo Yoshioka, Kazuhiko Ogawa, Yuichiro Doki, Masaki Mori, Hirofumi Yamamoto
Pages: 795-799 Published online on: 27 November 2013
Article
The CCL5/CCR5 axis contributes to the perineural invasion of human salivary adenoid cystic carcinoma
Zhiyuan Shen, Tianyi Li, Da Chen, Sen Jia, Xiangming Yang, Liang Liang, Juan Chai, Xiaobing Cheng, Xinjie Yang, Moyi Sun
Pages: 800-806 Published online on: 13 December 2013
Article
Rearrangements of chromosome bands 15q12-q21 are secondary to HMGA2 deregulation in conventional lipoma
Gemma Macchia, Karolin H. Nord, Giuseppina D'Alessandro, Jenny Nilsson, Linda Magnusson, Nils Mandahl, Clelia Tiziana Storlazzi, Fredrik Mertens
Pages: 807-811 Published online on: 02 December 2013
Article
Knockdown of Slit2 promotes growth and motility in gastric cancer cells via activation of AKT/β-catenin
Rongliang Shi, Zhen Yang, Weiyan Liu, Bingya Liu, Ziping Xu, Ziping Zhang
Pages: 812-818 Published online on: 02 December 2013
Article
Inhibition of CD73 stimulates the migration and invasion of B16F10 melanoma cells in vitro, but results in impaired angiogenesis and reduced melanoma growth in vivo
Patrycja Koszałka, Anna Pryszlak, Monika Gołuńska, Justyna Kolasa, Grzegorz Stasiłojć, Andrzej C. Składanowski, Jacek J. Bigda
Pages: 819-827 Published online on: 29 November 2013
Article
Allograft inflammatory factor-1 is an independent prognostic indicator that regulates β-catenin in gastric cancer
Yang Ye, Shuhan Miao, Rongzhu Lu, Xiaowei Xia, Yansu Chen, Jianbing Zhang, Xuming Wu, Song He, Fulin Qiang, Jianwei Zhou
Pages: 828-834 Published online on: 12 December 2013
Article
Inhibition of IL-6 expression in LNCaP prostate cancer cells by a combination of atorvastatin and celecoxib
Huaqian Wang, Xiao-Xing Cui, Susan Goodin, Ning Ding, Jeremiah Van Doren, Zhiyun Du, Mou-Tuan Huang, Yue Liu, Xiaodong Cheng, Robert S. Dipaola, Allan H. Conney, Xi Zheng
Pages: 835-841 Published online on: 29 November 2013
Article
Voltage-gated and ATP-sensitive K+ channels are associated with cell proliferation and tumorigenesis of human glioma
Qin Ru, Xiang Tian, Yu-Xiang Wu, Ri-Hui Wu, Ming-Shan Pi, Chao-Ying Li
Pages: 842-848 Published online on: 27 November 2013
Article
Pseudolaric acid B induces caspase-dependent cell death in human ovarian cancer cells
Bo Yu, Dong-Mei Yue, Lin-Hua Shu, Nai-Jing Li, Jia-He Wang
Pages: 849-857 Published online on: 25 November 2013
Article
β-elemene, a compound derived from Rhizoma zedoariae, reverses multidrug resistance mediated by the ABCB1 transporter
Hui-Qin Guo, Guan-Nan Zhang, Yi-Jun Wang, Yun-Kai Zhang, Kamlesh Sodani, Tanaji T. Talele, Charles R. Ashby, Zhe-Sheng Chen
Pages: 858-866 Published online on: 27 November 2013
Article
Silencing Dicer expression enhances cellular proliferative and invasive capacities in human tongue squamous cell carcinoma
Shuguang Zeng, Jing Yang, Jianjiang Zhao, Qicai Liu, Mingdeng Rong, Zehong Guo, Wenfeng Gao
Pages: 867-873 Published online on: 06 December 2013
Article
Cells susceptible to epithelial-mesenchymal transition are enriched in stem-like side population cells from prostate cancer
Yong Luo, Xinhao Cui, Jiahui Zhao, Yili Han, Mingchuan Li, Yunhua Lin, Yongguang Jiang, Ling Lan
Pages: 874-884 Published online on: 06 December 2013
Article
Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis
Lufang Chen, Xiaodong Lu, Tiantian Zeng, Yuanyuan Chen, Qian Chen, Weijiang Wu, Xun Yan, Honghua Cai, Zhijian Zhang, Qixiang Shao, Wenxin Qin
Pages: 885-893 Published online on: 06 December 2013
Article
Phosphoglycerate kinase 1 promotes radioresistance in U251 human glioma cells
Hao Ding, Yi-Jun Cheng, Hua Yan, Rui Zhang, Jin-Bing Zhao, Chun-Fa Qian, Wen-Bin Zhang, Hong Xiao, Hong-Yi Liu
Pages: 894-900 Published online on: 27 November 2013
Article
APE1/Ref-1 enhances DNA binding activity of mutant p53 in a redox-dependent manner
Yanping Cun, Nan Dai, Mengxia Li, Chengjie Xiong, Qinhong Zhang, Jiangdong Sui, Chengyuan Qian, Dong Wang
Pages: 901-909 Published online on: 02 December 2013
Article
miR-200b suppresses cell proliferation, migration and enhances chemosensitivity in prostate cancer by regulating Bmi-1
Junjie Yu, Youyi Lu, Di Cui, Enhui Li, Yipin Zhu, Yuyang Zhao, Fujun Zhao, Shujie Xia
Pages: 910-918 Published online on: 05 December 2013
Article
Ginsenoside Rg3 induces DNA damage in human osteosarcoma cells and reduces MNNG-induced DNA damage and apoptosis in normal human cells
Yue-Hui Zhang, Hai-Dong Li, Bo Li, Sheng-Dan Jiang, Lei-Sheng Jiang
Pages: 919-925 Published online on: 11 December 2013
Article
Investigation of the mechanism involved in the As2O3-regulated decrease in MDR1 expression in leukemia cells
Feng Gao, Jia Liu, Wan Wei Dong, Wei Wang, Ying Wang, Dali Cai, Zhihong Zheng, Kailai Sun
Pages: 926-932 Published online on: 16 December 2013
Article
Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma
Qian Sun, Ronghua Wang, Yan Wang, Jing Luo, Peng Wang, Bin Cheng
Pages: 933-939 Published online on: 12 December 2013
Article
Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe
Maria Raffaella Greco, Ester Antelmi, Giovanni Busco, Lorenzo Guerra, Rosa Rubino, Valeria Casavola, Stephan Joel Reshkin, Rosa Angela Cardone
Pages: 940-946 Published online on: 13 December 2013
Article
Peroxisome proliferator-activated receptor γ ligand troglitazone and TRAIL synergistically induce apoptosis
Makoto Koyama, Yoshihiro Sowa, Mano Horinaka, Ahmed E. Goda, Jun Fujiwara, Toshiyuki Sakai
Pages: 947-954 Published online on: 25 November 2013
Article
In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma
Michel Pinheiro Dos Santos, Caroline Brunetto de Farias, Rafael Roesler, Algemir Lunardi Brunetto, Ana Lucia Abujamra
Pages: 955-968 Published online on: 06 December 2013
Article
Levels of cell-free DNA and plasma KRAS during treatment of advanced NSCLC
Anneli Dowler Nygaard, Karen-Lise Garm Spindler, Niels Pallisgaard, Rikke Fredslund Andersen, Anders Jakobsen
Pages: 969-974 Published online on: 06 December 2013
Article
Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53- and caspase-dependent induction of p38 MAPK
He-Qi Bu, Dian-Lei Liu, Wei-Tian Wei, Liang Chen, Hai Huang, Ye Li, Jun-Hui Cui
Pages: 975-982 Published online on: 02 December 2013
Article
Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells
Shigeki Nakagawa, Yasuo Sakamoto, Hirohisa Okabe, Hiromitsu Hayashi, Daisuke Hashimoto, Naomi Yokoyama, Ryuma Tokunaga, Keita Sakamoto, Hideyuki Kuroki, Kosuke Mima, Toru Beppu, Hideo Baba
Pages: 983-988 Published online on: 13 December 2013
Article
Bone morphogenetic protein 9 regulates tumor growth of osteosarcoma cells through the Wnt/β-catenin pathway
Zilan Lv, Chuan Wang, Taixian Yuan, Yuehong Liu, Tao Song, Yueliang Liu, Chu Chen, Min Yang, Zuchuan Tang, Qiong Shi, Yaguang Weng
Pages: 989-994 Published online on: 16 December 2013
Article
Polymorphisms of the pri-miR-34b/c promoter and TP53 codon 72 are associated with risk of colorectal cancer
Jisu Oh, Jong Woo Kim, Bo Eun Lee, Moon Ju Jang, So Young Chong, Pil Won Park, Seong Gyu Hwang, Doyeun Oh, Nam Keun Kim
Pages: 995-1002 Published online on: 13 December 2013
Article
A multimarker qPCR platform for the characterisation of endometrial cancer
Anna Supernat, Sylwia Łapińska-Szumczyk, Hanna Majewska, Jacek Gulczyński, Wojciech Biernat, Dariusz Wydra, Anna J. Żaczek
Pages: 1003-1013 Published online on: 13 December 2013
Article
Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer
Semra Demokan, Alice Y. Chuang, Kavita M. Pattani, David Sidransky, Wayne Koch, Joseph A. Califano
Pages: 1014-1020 Published online on: 16 December 2013
Article
Suppression of VEGF expression through interruption of the HIF‑1α and Akt signaling cascade modulates the anti‑angiogenic activity of DAPK in ovarian carcinoma cells
Sung Taek Park, Boh-Ram Kim, Sung Ho Park, Jeong Heon Lee, Eun-Ju Lee, Seung-Hoon Lee, Seung Bae Rho
Pages: 1021-1029 Published online on: 16 December 2013
Correction
