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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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2014-February Volume 31 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Epigenetic regulation and cancer (Review)

Q. W. Chen, X. Y. Zhu, Y. Y. Li, Z. Q. Meng
Pages: 523-532
Published online on: 11 December 2013

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Review

Wnt1 inducible signalling pathway protein-2 (WISP‑2/CCN5): Roles and regulation in human cancers (Review)

Jiafu Ji, Shuqin Jia, Ke Ji, Wen G. Jiang
Pages: 533-539
Published online on: 09 December 2013

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Article Open Access

Connexin-dependent gap junction enhancement is involved in the synergistic effect of sorafenib and all-trans retinoic acid on HCC growth inhibition

Yan Yang, Shu-Kui Qin, Qiong Wu, Zi-Shu Wang, Rong-Sheng Zheng, Xu-Hui Tong, Hao Liu, Liang Tao, Xian-Di He
Pages: 540-550
Published online on: 05 December 2013

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Article Open Access

Natural and glucosyl flavonoids inhibit poly(ADP-ribose) polymerase activity and induce synthetic lethality in BRCA mutant cells

Junko Maeda, Erica J. Roybal, Colleen A. Brents, Mitsuru Uesaka, Yasushi Aizawa, Takamitsu A. Kato
Pages: 551-556
Published online on: 05 December 2013

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Article Open Access

Bioinformatic analysis of the membrane cofactor protein CD46 and microRNA expression in hepatocellular carcinoma

Zejun Lu, Chuanfu Zhang, Jiajun Cui, Qi Song, Ligui Wang, Jingbo Kang, Peng Li, Xiaofeng Hu, Hongbin Song, Jinliang Yang, Yansong Sun
Pages: 557-564
Published online on: 28 November 2013

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Article Open Access

Proposal for a new mediastinal compartment classification of transverse plane images according to the Japanese Association for Research on the Thymus (JART) General Rules for the Study of Mediastinal Tumors

Kiminori Fujimoto, Masaki Hara, Noriyuki Tomiyama, Masahiko Kusumoto, Fumikazu Sakai, Yoshitaka Fujii
Pages: 565-572
Published online on: 06 December 2013

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Article Open Access

Active form of AKT controls cell proliferation and response to apoptosis in hepatocellular carcinoma

Imge Kunter, Esra Erdal, Deniz Nart, Funda Yilmaz, Sedat Karademir, Ozgul Sagol, Nese Atabey
Pages: 573-580
Published online on: 16 December 2013

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Article Open Access

Capsaicin induces apoptosis in PC12 cells through ER stress

Olga Krizanova, Iveta Steliarova, Lucia Csaderova, Michal Pastorek, Sona Hudecova
Pages: 581-588
Published online on: 13 December 2013

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Article

Mesenchymal phenotype after chemotherapy is associated with chemoresistance and poor clinical outcome in esophageal cancer

Johji Hara, Hiroshi Miyata, Makoto Yamasaki, Keijiro Sugimura, Tsuyoshi Takahashi, Yukinori Kurokawa, Kiyokazu Nakajima, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
Pages: 589-596
Published online on: 28 November 2013

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Article

Hepatocyte growth factor and HER2/neu downregulate expression of apoptosis-inducing factor in non-small cell lung cancer

Yung-Yen Chiang, Kuan-Chih Chow, Tze-Yi Lin, I-Ping Chiang, Hsing-Yuan Fang
Pages: 597-604
Published online on: 25 November 2013

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Article

Prognostic significance of IL-17 mRNA expression in peritoneal lavage in gastric cancer patients who underwent curative resection

Takeshi Iida, Makoto Iwahashi, Masahiro Katsuda, Koichiro Ishida, Mikihito Nakamori, Masaki Nakamura, Teiji Naka, Toshiyasu Ojima, Kentaro Ueda, Keiji Hayata, Hironao Yasuoka, Hiroki Yamaue
Pages: 605-612
Published online on: 10 December 2013

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Article

Relapse-associated microRNA in gastric cancer patients after S-1 adjuvant chemotherapy

Tetsuya Omura, Yutaka Shimada, Takuya Nagata, Tomoyuki Okumura, Junya Fukuoka, Fuminori Yamagishi, Sadakatsu Tajika, Sanae Nakajima, Atsushi Kawabe, Kazuhiro Tsukada
Pages: 613-618
Published online on: 05 December 2013

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Article

The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway

Takashi Ui, Kazue Morishima, Shin Saito, Yuji Sakuma, Hirofumi Fujii, Yoshinori Hosoya, Shumpei Ishikawa, Hiroyuki Aburatani, Masashi Fukayama, Toshiro Niki, Yoshikazu Yasuda
Pages: 619-624
Published online on: 05 December 2013

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Article

(-)-Epigallocatechin-3-gallate suppresses liver metastasis of human colorectal cancer

Takehito Maruyama, Soichiro Murata, Ken Nakayama, Naoki Sano, Koichi Ogawa, Takeshi Nowatari, Takafumi Tamura, Reiji Nozaki, Kiyoshi Fukunaga, Nobuhiro Ohkohchi
Pages: 625-633
Published online on: 13 December 2013

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Article

Mina53, a novel molecular marker for the diagnosis and prognosis of gastric adenocarcinoma

Jing Xing, Ke Wang, Peng-Wei Liu, Qi Miao, Xiao-Yu Chen
Pages: 634-640
Published online on: 12 December 2013

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Article

Activated hepatic stellate cells promote hepatocellular carcinoma cell migration and invasion via the activation of FAK-MMP9 signaling

Shaoshan Han, Lei Han, Yingmin Yao, Hao Sun, Xianfeng Zan, Qingguang Liu
Pages: 641-648
Published online on: 27 November 2013

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Article

AZD8055 induces cell death associated with autophagy and activation of AMPK in hepatocellular carcinoma

Min Hu, Haili Huang, Rui Zhao, Peng Li, Mingyi Li, Huilai Miao, Nianping Chen, Ming Chen
Pages: 649-656
Published online on: 02 December 2013

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Article

Establishment of a green fluorescent protein tracing murine model focused on the functions of host components in necrosis repair and the niche of subcutaneously implanted glioma

Zhao-Hui Lu, Ke Lv, Jin-Shi Zhang, Chun-Gang Dai, Bin Liu, Xiao-Yu Ma, Lin-Ming He, Jing-Yun Jia, Yan-Ming Chen, Xing-Liang Dai, Ai-Dong Wang, Jun Dong, Quan-Bin Zhang, Qing Lan, Qiang Huang
Pages: 657-664
Published online on: 27 November 2013

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Article

Clinical significance of TrkB expression in nasopharyngeal carcinoma

Shi-Sheng Li, Jia-Jia Liu, Shuang Wang, Qing-Lai Tang, Bing-Bing Liu, Xin-Ming Yang
Pages: 665-672
Published online on: 28 November 2013

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Article

Genistein attenuates cancer stem cell characteristics in gastric cancer through the downregulation of Gli1

Dayeon Yu, Hyun-Soo Shin, Yeo Song Lee, Doyeon Lee, Shin Kim, Yong Chan Lee
Pages: 673-678
Published online on: 02 December 2013

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Article

Expression of tissue factor signaling pathway elements correlates with the production of vascular endothelial growth factor and interleukin-8 in human astrocytoma patients

Tatiana C. Carneiro-Lobo, Marina T. Lima, Andréa Mariano‑Oliveira, Angélica Dutra‑Oliveira, Sueli M. Oba-Shinjo, Suely K.N. Marie, Mari C. Sogayar, Robson Q. Monteiro
Pages: 679-686
Published online on: 28 November 2013

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Article

Identification of natural splice variants of SAMHD1 in virus-infected HCC

Yunpeng Shi, Guoyue Lv, Zhe Chu, Liling Piao, Xingkai Liu, Tuo Wang, Yanfang Jiang, Ping Zhang
Pages: 687-692
Published online on: 05 December 2013

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Article

Reduced expression of DENND2D through promoter hypermethylation is an adverse prognostic factor in squamous cell carcinoma of the esophagus

Soki Hibino, Mitsuro Kanda, Hisaharu Oya, Hideki Takami, Dai Shimizu, Shuji Nomoto, Mitsuhiro Hishida, Yukiko Niwa, Masahiko Koike, Suguru Yamada, Yoko Nishikawa, Mikako Asai, Goro Nakayama, Tsutomu Fujii, Hiroyuki Sugimoto, Michitaka Fujiwara, Yasuhiro Kodera
Pages: 693-700
Published online on: 05 December 2013

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Article

Molecular mechanisms of [18F]fluorodeoxyglucose accumulation in liver cancer

Kunihiko Izuishi, Yuka Yamamoto, Hirohito Mori, Riko Kameyama, Shintaro Fujihara, Tsutomu Masaki, Yasuyuki Suzuki
Pages: 701-706
Published online on: 29 November 2013

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Article

Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells

Yonghua Xu, Yong An, Xuehao Wang, Wenzhang Zha, Xiangcheng Li
Pages: 707-712
Published online on: 28 November 2013

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Article

Novel EXT1 mutation identified in a pedigree with hereditary multiple exostoses

Li Cao, Fei Liu, Mingxiang Kong, Yong Fang, Haifeng Gu, Yu Chen, Chen Zhao, Shuijun Zhang, Qing Bi
Pages: 713-718
Published online on: 02 December 2013

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Article

Factors involved in the cisplatin resistance of KCP‑4 human epidermoid carcinoma cells

Shigeru Oiso, Yui Takayama, Rie Nakazaki, Naoko Matsunaga, Chie Motooka, Asuka Yamamura, Ryuji Ikeda, Kazuo Nakamura, Yasuo Takeda, Hiroko Kariyazono
Pages: 719-726
Published online on: 05 December 2013

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Article

Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell-like side population cells Expression of Concern in /10.3892/or.2025.9006

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Pages: 727-736
Published online on: 13 December 2013

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Article

Distinct roles of Akt1 in regulating proliferation, migration and invasion in HepG2 and HCT 116 cells

Liang Chen, Qiao-Hui Kang, Ying Chen, Ya-Hong Zhang, Qian Li, Song-Qiang Xie, Chao-Jie Wang
Pages: 737-744
Published online on: 28 November 2013

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Article

Upregulation of NEK2 is associated with drug resistance in ovarian cancer

Xia Liu, Yutao Gao, Yi Lu, Jian Zhang, Li Li, Fuqiang Yin
Pages: 745-754
Published online on: 09 December 2013

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Article

Licochalcone A induces apoptosis in KB human oral cancer cells via a caspase-dependent FasL signaling pathway

Jae-Sung Kim, Mi-Ra Park, Sook-Young Lee, Do Kyoung Kim, Sung‑Min Moon, Chun Sung Kim, Seung Sik Cho, Goo Yoon, Hee-Jeong Im, Jae‑Seek You, Ji-Su Oh, Su-Gwan Kim
Pages: 755-762
Published online on: 16 December 2013

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Article

Pien Tze Huang induces apoptosis in multidrug‑resistant U2OS/ADM cells via downregulation of Bcl‑2, survivin and P-gp and upregulation of Bax

Yan Zhang, Qihong Wang, Susheng Niu, Junning Liu, Li Zhang
Pages: 763-770
Published online on: 12 December 2013

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Article

Therapeutic potential of sepantronium bromide YM155 in gemcitabine-resistant human urothelial carcinoma cells

Yen Ta Huang, Chuan Chu Cheng, Tzu Chun Lin, Ted H. Chiu, Pei Chun Lai
Pages: 771-780
Published online on: 28 November 2013

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Article

A preliminary study on the construction of double suicide gene delivery vectors by mesenchymal stem cells and the in vitro inhibitory effects on SKOV3 cells

Jingyan Jiang, Dee Wei, Li Sun, Yuxia Wang, Xihai Wu, Ying Li, Zhenghui Fang, Hui Shang, Zengtao Wei
Pages: 781-787
Published online on: 05 December 2013

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Article

Expression of early growth response-1 in colorectal cancer and its relation to tumor cell proliferation and apoptosis

Dae-Seong Myung, Young-Lan Park, Nuri Kim, Cho-Yun Chung, Hyung-Chul Park, Jong-Sun Kim, Sung-Bum Cho, Wan-Sik Lee, Jae-Hyuk Lee, Young-Eun Joo
Pages: 788-794
Published online on: 29 November 2013

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Article

Impact of stereotactic body radiotherapy on colorectal cancer with distant metastases

Masayuki Hiraki, Junichi Nishimura, Masahisa Ohtsuka, Hiroya Shiomi, Mamoru Uemura, Naotsugu Haraguchi, Taishi Hata, Taro Hayashi, Ichiro Takemasa, Tsunekazu Mizushima, Fumiaki Isohashi, Yasuo Yoshioka, Kazuhiko Ogawa, Yuichiro Doki, Masaki Mori, Hirofumi Yamamoto
Pages: 795-799
Published online on: 27 November 2013

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Article

The CCL5/CCR5 axis contributes to the perineural invasion of human salivary adenoid cystic carcinoma

Zhiyuan Shen, Tianyi Li, Da Chen, Sen Jia, Xiangming Yang, Liang Liang, Juan Chai, Xiaobing Cheng, Xinjie Yang, Moyi Sun
Pages: 800-806
Published online on: 13 December 2013

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Article

Rearrangements of chromosome bands 15q12-q21 are secondary to HMGA2 deregulation in conventional lipoma

Gemma Macchia, Karolin H. Nord, Giuseppina D'Alessandro, Jenny Nilsson, Linda Magnusson, Nils Mandahl, Clelia Tiziana Storlazzi, Fredrik Mertens
Pages: 807-811
Published online on: 02 December 2013

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Article

Knockdown of Slit2 promotes growth and motility in gastric cancer cells via activation of AKT/β-catenin

Rongliang Shi, Zhen Yang, Weiyan Liu, Bingya Liu, Ziping Xu, Ziping Zhang
Pages: 812-818
Published online on: 02 December 2013

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Article

Inhibition of CD73 stimulates the migration and invasion of B16F10 melanoma cells in vitro, but results in impaired angiogenesis and reduced melanoma growth in vivo

Patrycja Koszałka, Anna Pryszlak, Monika Gołuńska, Justyna Kolasa, Grzegorz Stasiłojć, Andrzej C. Składanowski, Jacek J. Bigda
Pages: 819-827
Published online on: 29 November 2013

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Article

Allograft inflammatory factor-1 is an independent prognostic indicator that regulates β-catenin in gastric cancer

Yang Ye, Shuhan Miao, Rongzhu Lu, Xiaowei Xia, Yansu Chen, Jianbing Zhang, Xuming Wu, Song He, Fulin Qiang, Jianwei Zhou
Pages: 828-834
Published online on: 12 December 2013

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Article

Inhibition of IL-6 expression in LNCaP prostate cancer cells by a combination of atorvastatin and celecoxib

Huaqian Wang, Xiao-Xing Cui, Susan Goodin, Ning Ding, Jeremiah Van Doren, Zhiyun Du, Mou-Tuan Huang, Yue Liu, Xiaodong Cheng, Robert S. Dipaola, Allan H. Conney, Xi Zheng
Pages: 835-841
Published online on: 29 November 2013

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Article

Voltage-gated and ATP-sensitive K+ channels are associated with cell proliferation and tumorigenesis of human glioma

Qin Ru, Xiang Tian, Yu-Xiang Wu, Ri-Hui Wu, Ming-Shan Pi, Chao-Ying Li
Pages: 842-848
Published online on: 27 November 2013

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Article

Pseudolaric acid B induces caspase-dependent cell death in human ovarian cancer cells

Bo Yu, Dong-Mei Yue, Lin-Hua Shu, Nai-Jing Li, Jia-He Wang
Pages: 849-857
Published online on: 25 November 2013

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Article

β-elemene, a compound derived from Rhizoma zedoariae, reverses multidrug resistance mediated by the ABCB1 transporter

Hui-Qin Guo, Guan-Nan Zhang, Yi-Jun Wang, Yun-Kai Zhang, Kamlesh Sodani, Tanaji T. Talele, Charles R. Ashby, Zhe-Sheng Chen
Pages: 858-866
Published online on: 27 November 2013

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Article

Silencing Dicer expression enhances cellular proliferative and invasive capacities in human tongue squamous cell carcinoma

Shuguang Zeng, Jing Yang, Jianjiang Zhao, Qicai Liu, Mingdeng Rong, Zehong Guo, Wenfeng Gao
Pages: 867-873
Published online on: 06 December 2013

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Article

Cells susceptible to epithelial-mesenchymal transition are enriched in stem-like side population cells from prostate cancer

Yong Luo, Xinhao Cui, Jiahui Zhao, Yili Han, Mingchuan Li, Yunhua Lin, Yongguang Jiang, Ling Lan
Pages: 874-884
Published online on: 06 December 2013

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Article

Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis

Lufang Chen, Xiaodong Lu, Tiantian Zeng, Yuanyuan Chen, Qian Chen, Weijiang Wu, Xun Yan, Honghua Cai, Zhijian Zhang, Qixiang Shao, Wenxin Qin
Pages: 885-893
Published online on: 06 December 2013

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Article

Phosphoglycerate kinase 1 promotes radioresistance in U251 human glioma cells

Hao Ding, Yi-Jun Cheng, Hua Yan, Rui Zhang, Jin-Bing Zhao, Chun-Fa Qian, Wen-Bin Zhang, Hong Xiao, Hong-Yi Liu
Pages: 894-900
Published online on: 27 November 2013

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Article

APE1/Ref-1 enhances DNA binding activity of mutant p53 in a redox-dependent manner

Yanping Cun, Nan Dai, Mengxia Li, Chengjie Xiong, Qinhong Zhang, Jiangdong Sui, Chengyuan Qian, Dong Wang
Pages: 901-909
Published online on: 02 December 2013

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Article

miR-200b suppresses cell proliferation, migration and enhances chemosensitivity in prostate cancer by regulating Bmi-1

Junjie Yu, Youyi Lu, Di Cui, Enhui Li, Yipin Zhu, Yuyang Zhao, Fujun Zhao, Shujie Xia
Pages: 910-918
Published online on: 05 December 2013

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Article

Ginsenoside Rg3 induces DNA damage in human osteosarcoma cells and reduces MNNG-induced DNA damage and apoptosis in normal human cells

Yue-Hui Zhang, Hai-Dong Li, Bo Li, Sheng-Dan Jiang, Lei-Sheng Jiang
Pages: 919-925
Published online on: 11 December 2013

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Article

Investigation of the mechanism involved in the As2O3-regulated decrease in MDR1 expression in leukemia cells

Feng Gao, Jia Liu, Wan Wei Dong, Wei Wang, Ying Wang, Dali Cai, Zhihong Zheng, Kailai Sun
Pages: 926-932
Published online on: 16 December 2013

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Article

Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma

Qian Sun, Ronghua Wang, Yan Wang, Jing Luo, Peng Wang, Bin Cheng
Pages: 933-939
Published online on: 12 December 2013

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Article

Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe

Maria Raffaella Greco, Ester Antelmi, Giovanni Busco, Lorenzo Guerra, Rosa Rubino, Valeria Casavola, Stephan Joel Reshkin, Rosa Angela Cardone
Pages: 940-946
Published online on: 13 December 2013

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Article

Peroxisome proliferator-activated receptor γ ligand troglitazone and TRAIL synergistically induce apoptosis

Makoto Koyama, Yoshihiro Sowa, Mano Horinaka, Ahmed E. Goda, Jun Fujiwara, Toshiyuki Sakai
Pages: 947-954
Published online on: 25 November 2013

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In vitro antitumor effect of sodium butyrate and zoledronic acid combined with traditional chemotherapeutic drugs: a paradigm of synergistic molecular targeting in the treatment of Ewing sarcoma

Michel Pinheiro Dos Santos, Caroline Brunetto de Farias, Rafael Roesler, Algemir Lunardi Brunetto, Ana Lucia Abujamra
Pages: 955-968
Published online on: 06 December 2013

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Levels of cell-free DNA and plasma KRAS during treatment of advanced NSCLC

Anneli Dowler Nygaard, Karen-Lise Garm Spindler, Niels Pallisgaard, Rikke Fredslund Andersen, Anders Jakobsen
Pages: 969-974
Published online on: 06 December 2013

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Oridonin induces apoptosis in SW1990 pancreatic cancer cells via p53- and caspase-dependent induction of p38 MAPK

He-Qi Bu, Dian-Lei Liu, Wei-Tian Wei, Liang Chen, Hai Huang, Ye Li, Jun-Hui Cui
Pages: 975-982
Published online on: 02 December 2013

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Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells

Shigeki Nakagawa, Yasuo Sakamoto, Hirohisa Okabe, Hiromitsu Hayashi, Daisuke Hashimoto, Naomi Yokoyama, Ryuma Tokunaga, Keita Sakamoto, Hideyuki Kuroki, Kosuke Mima, Toru Beppu, Hideo Baba
Pages: 983-988
Published online on: 13 December 2013

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Bone morphogenetic protein 9 regulates tumor growth of osteosarcoma cells through the Wnt/β-catenin pathway

Zilan Lv, Chuan Wang, Taixian Yuan, Yuehong Liu, Tao Song, Yueliang Liu, Chu Chen, Min Yang, Zuchuan Tang, Qiong Shi, Yaguang Weng
Pages: 989-994
Published online on: 16 December 2013

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Polymorphisms of the pri-miR-34b/c promoter and TP53 codon 72 are associated with risk of colorectal cancer

Jisu Oh, Jong Woo Kim, Bo Eun Lee, Moon Ju Jang, So Young Chong, Pil Won Park, Seong Gyu Hwang, Doyeun Oh, Nam Keun Kim
Pages: 995-1002
Published online on: 13 December 2013

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A multimarker qPCR platform for the characterisation of endometrial cancer

Anna Supernat, Sylwia Łapińska-Szumczyk, Hanna Majewska, Jacek Gulczyński, Wojciech Biernat, Dariusz Wydra, Anna J. Żaczek
Pages: 1003-1013
Published online on: 13 December 2013

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Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer

Semra Demokan, Alice Y. Chuang, Kavita M. Pattani, David Sidransky, Wayne Koch, Joseph A. Califano
Pages: 1014-1020
Published online on: 16 December 2013

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Suppression of VEGF expression through interruption of the HIF‑1α and Akt signaling cascade modulates the anti‑angiogenic activity of DAPK in ovarian carcinoma cells

Sung Taek Park, Boh-Ram Kim, Sung Ho Park, Jeong Heon Lee, Eun-Ju Lee, Seung-Hoon Lee, Seung Bae Rho
Pages: 1021-1029
Published online on: 16 December 2013

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Correction Open Access

[Erratum] Expression of junB is markedly stimulated by glycyrrhizin in a human hepatoma cell line

Katsuro Koike
Pages: 1030-1030
Published online on: 10 December 2013

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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