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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2021 Volume 24 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

miR‑101a‑3p overexpression prevents acetylcholine‑CaCl2‑induced atrial fibrillation in rats via reduction of atrial tissue fibrosis, involving inhibition of EZH2

Jing Zhu, Ning Zhu, Jian Xu
Article Number: 740
Published online on: 20 August 2021

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Article Open Access

Assessing the protective effects of cryptotanshinone on CoCl2‑induced hypoxia in RPE cells

Yu Gu, Weiming Liu, Gaoqin Liu, Xin Li, Peirong Lu
Article Number: 739
Published online on: 20 August 2021

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Article Open Access

Role of the CXCR3‑mediated TLRs/MyD88 signaling pathway in promoting the development of hepatitis B into cirrhosis and liver cancer

Gang Yuan, Bin Chen, Yina Meng, Jialin Lu, Xiaojun Shi, Airong Hu, Yaoren Hu, Donghui Wang
Article Number: 738
Published online on: 20 August 2021

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Article Open Access

Porcine pancreas mesenchymal cell characterization and functional differentiation into insulin‑producing cells in vitro

Shang Zhang, Qi Wang, Hongbing Ji, Huidi Lu, Qin Yang, Jiahui Yin, Weijun Guan
Article Number: 737
Published online on: 17 August 2021

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Article Open Access

Polyherbal formulation Anoac‑H suppresses the expression of RANTES and VEGF for the management of bleeding hemorrhoids and fistula

Ashwin Porwal, Gopal C. Kundu, Gajanan Bhagwat, Ramesh Butti
Article Number: 736
Published online on: 16 August 2021

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Article Open Access

hsa‑miR‑15a‑5p inhibits colon cell carcinoma via targeting CCND1

Zhipeng Li, Zeyu Zhu, Yanjun Wang, Ying Wang, Weibing Li, Zhigang Wang, Xinyuan Zhou, Yuhua Bao
Article Number: 735
Published online on: 16 August 2021

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Review Open Access

Roles of α‑synuclein in gastrointestinal microbiome dysbiosis‑related Parkinson's disease progression (Review)

Qingchun Lei, Tingting Wu, Jin Wu, Xiaogang Hu, Yingxia Guan, Ying Wang, Jinyuan Yan, Guolin Shi
Article Number: 734
Published online on: 16 August 2021

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Article

Intermedin1‑47 inhibits high phosphate‑induced vascular smooth muscle cell calcification by regulating Wnt/β‑catenin signaling

Yin Zhang, Naiwang Tang, Jinjie Zhou
Article Number: 733
Published online on: 16 August 2021

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Review Open Access

Theories behind the effect of starch‑ and sucrose‑reduced diets on gastrointestinal symptoms in irritable bowel syndrome (Review)

Bodil Ohlsson
Article Number: 732
Published online on: 16 August 2021

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Article Open Access

A microRNA‑17‑5p/homeobox B13 axis participates in the phenotypic modulation of vascular smooth muscle cells

Tianchi Yu, Tao Wang, Shifang Kuang, Guoping Zhao, Kun Zhou, Hui Zhang
Article Number: 731
Published online on: 16 August 2021

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Article Open Access

Ulinastatin protects against sepsis‑induced myocardial injury by inhibiting NLRP3 inflammasome activation

Juanjuan Qiu, Xiaoguang Xiao, Xue Gao, Yongli Zhang
Article Number: 730
Published online on: 16 August 2021

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Article Open Access

Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway

Dongdong Li, Luobing Wang, Jiaoying Ou, Chuanxu Wang, Jiabao Zhou, Lili Lu, Yanshneg Wu, Jiandong Gao
Article Number: 729
Published online on: 13 August 2021

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Article Open Access

Circular RNA OMA1 regulates the progression of breast cancer via modulation of the miR‑1276/SIRT4 axis

Lingli Xu, Ke Xu, Lijun Xiang, Jiamei Yan
Article Number: 728
Published online on: 13 August 2021

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Retraction Open Access

[Retracted] Upregulation of microRNA‑27b contributes to the migration and invasion of gastric cancer cells via the inhibition of sprouty2‑mediated ERK signaling

Juan Jiang, Bo Yi, Chunxiang Qin, Siqing Ding, Wei Cao
Article Number: 727
Published online on: 13 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑145 inhibits migration and invasion via inhibition of fascin 1 protein expression in non‑small‑cell lung cancer cells

Yingying Zhang, Xucheng Yang, Haijun Wu, Weibin Zhou, Zhenzhen Liu
Article Number: 726
Published online on: 12 August 2021

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Article Open Access

Alcohol inhibits alveolar fluid clearance through the epithelial sodium channel via the A2 adenosine receptor in acute lung injury

Wang Deng, Jing He, Xu-Mao Tang, Chang-Yi Li, Jin Tong, Di Qi, Dao-Xin Wang
Article Number: 725
Published online on: 11 August 2021

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Article

MicroRNA‑25 protects nucleus pulposus cells against apoptosis via targeting SUMO2 in intervertebral disc degeneration Retraction in /10.3892/mmr.2024.13212

Changbin Lei, Jian Li, Guang Tang, Jiong Wang
Article Number: 724
Published online on: 11 August 2021

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Article Open Access

miR‑4306 inhibits the malignant behaviors of colorectal cancer by regulating lncRNA FoxD2‑AS1 Retraction in /10.3892/mmr.2024.13299

Jinjun Ye, Jidong Liu, Tao Tang, Le Xin, Xing Bao, Yukuang Yan
Article Number: 723
Published online on: 11 August 2021

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Article Open Access

HOXB13 suppresses proliferation, migration and invasion, and promotes apoptosis of gastric cancer cells through transcriptional activation of VGLL4 to inhibit the involvement of TEAD4 in the Hippo signaling pathway

Hui Geng, Guangli Liu, Jiandong Hu, Jianchao Li, Dong Wang, Shenshan Zou, Xintao Xu
Article Number: 722
Published online on: 11 August 2021

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Article Open Access

Chemosensitivity analysis and study of gene resistance on tumors and cancer stem cell isolates from patients with colorectal cancer

Elsa N. Garza‑Treviño, Herminia G. Martínez‑Rodríguez, Paulina Delgado‑González, Orlando Solís‑Coronado, Rocio Ortíz‑Lopez, Adolfo Soto‑Domínguez, Víctor M. Treviño, Gerardo R. Padilla‑Rivas, Jose F. Islas‑Cisneros, Adriana G. Quiroz‑Reyes, Salvador L. Said‑Fernández
Article Number: 721
Published online on: 11 August 2021

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Correction Open Access

[Corrigendum] Hsa‑circRNA‑G004213 promotes cisplatin sensitivity by regulating miR‑513b‑5p/PRPF39 in liver cancer

Ling Qin, Zibo Zan, Chunxue Wei, Xuemei Li, Tongqin Zhang, Jun Li
Article Number: 720
Published online on: 11 August 2021

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Article Open Access

Adiponectin inhibits D‑gal‑induced cardiomyocyte senescence via AdipoR1/APPL1

Ruiying Liu, Jing Meng, Danfei Lou
Article Number: 719
Published online on: 10 August 2021

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Article Open Access

Phylogenetic analysis of combined lobular and ductal carcinoma of the breast

Hiroko Kobayashi, Tokiko Nakai, Yoko Nakanishi, Mariko Esumi, Shinobu Masuda
Article Number: 718
Published online on: 10 August 2021

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Article

Inhibition of the p‑SPAK/p‑NKCC1 signaling pathway protects the blood‑brain barrier and reduces neuronal apoptosis in a rat model of surgical brain injury

Yating Gong, Muyao Wu, Fan Gao, Mengying Shi, Haiping Gu, Rong Gao, Bao-Qi Dang, Gang Chen
Article Number: 717
Published online on: 10 August 2021

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Article

CXCL16 may be a predisposing factor to atherosclerosis: An animal study

Junbi Zhao, Menglin Yang, Jie Wu
Article Number: 716
Published online on: 10 August 2021

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Article Open Access

Methylation profile of hepatitis B virus is not influenced by interferon α in human liver cancer cells

In Young Moon, Jin-Wook Kim
Article Number: 715
Published online on: 10 August 2021

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Review

Functional role of miR‑155 in physiological and pathological processes of liver injury (Review)

Xiao Feng, Jiaying Bao, Chunxia Song, Ling Xie, Xu Tan, Jiaqi Li, Huimin Jia, Miaomiao Tian, Jianni Qi, Chengyong Qin, Hongjun Bian
Article Number: 714
Published online on: 10 August 2021

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Article Open Access

Erastin‑induced ferroptosis causes physiological and pathological changes in healthy tissues of mice

Jing Zhao, Ben Xu, Qingqing Xiong, Yunfei Feng, Huahua Du
Article Number: 713
Published online on: 10 August 2021

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Article Open Access

Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4 Corrigendum in /10.3892/mmr.2025.13752

Yan Shi, Shu-Ai Hou
Article Number: 712
Published online on: 10 August 2021

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Article

lncRNA GAS5 regulates angiogenesis by targeting miR‑10a‑3p/VEGFA in osteoporosis

Wen Wu, Qiang Li, Yi-Feng Liu, Yong Li
Article Number: 711
Published online on: 09 August 2021

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Article Open Access

Cucurbitacin B enhances apoptosis in gefitinib resistant non‑small cell lung cancer by modulating the miR‑17‑5p/STAT3 axis

Baodan Yu, Lixia Zheng, Huiqin Tang, Weixin Wang, Yongping Lin
Article Number: 710
Published online on: 09 August 2021

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Article Open Access

Metformin inhibits cholesterol‑induced adhesion molecule expression via activating the AMPK signaling pathway in vascular smooth muscle cells

Qi Liu, Mengyue Yang, Lu Zhang, Ruoxi Zhang, Xingtao Huang, Xuedong Wang, Wenjuan Du, Jingbo Hou
Article Number: 709
Published online on: 09 August 2021

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Article Open Access

miR‑125a‑5p and miR‑7 inhibits the proliferation, migration and invasion of vascular smooth muscle cell by targeting EGFR

Hualan Zhou, Sen Lin, Youdong Hu, Dianxuan Guo, Yun Wang, Xia Li
Article Number: 708
Published online on: 09 August 2021

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Retraction Open Access

[Retracted] Effects of cyclooxygenase‑2 gene silencing on the biological behavior of SKOV3 ovarian cancer cells

Feng-Jun Guo, Jing-Yan Tian, Yue-Mei Jin, Ling Wang, Rui-Qi Yang, Man-Hua Cui
Article Number: 707
Published online on: 08 August 2021

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Review Open Access

Functional study of SCCD pathogenic gene UBIAD1 (Review)

Jumin Xie, Lingxing Li
Article Number: 706
Published online on: 06 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑144 acts as a tumor suppressor by targeting Rho‑associated coiled‑coil containing protein kinase 1 in osteosarcoma cells

Jianjun Huang, Ying Shi, Hui Li, Meisongzhu Yang, Guohong Liu
Article Number: 705
Published online on: 05 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑7 inhibits the malignant phenotypes of non‑small cell lung cancer in vitro by targeting Pax6

Jiashun Luo, Hui Li, Chunfang Zhang
Article Number: 704
Published online on: 05 August 2021

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Article

Canagliflozin is a potential cardioprotective drug but exerts no significant effects on pirarubicin‑induced cardiotoxicity in rats

Hongwei Shi, Qingfu Zeng, Yunjie Wei, Hong Yang, Heng Tang, Dan Wang, Peng Pu, Rui Feng
Article Number: 703
Published online on: 05 August 2021

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Article Open Access

Study of the pathology and the underlying molecular mechanism of tissue injury around hematoma following intracerebral hemorrhage

Jinglei Wang, Ying Chen, Jingjing Liang, Maosheng Cao, Jiabing Shen, Kaifu Ke
Article Number: 702
Published online on: 05 August 2021

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Article

Isoalantolactone alleviates ovalbumin‑induced asthmatic inflammation by reducing alternatively activated macrophage and STAT6/PPAR‑γ/KLF4 signals

Yunduan Song, Xiaozong Li, Fangfang Liu, Hongbo Zhu, Yao Shen
Article Number: 701
Published online on: 05 August 2021

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Article Open Access

Glutamate receptor, ionotropic, N‑methyl D‑aspartate‑associated protein 1 promotes colorectal cancer cell proliferation and metastasis, and is negatively regulated by miR‑296‑3p

Zaihua Yan, Peidong Li, Yuan Xue, Hongpeng Tian, Tong Zhou, Guangjun Zhang
Article Number: 700
Published online on: 04 August 2021

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Article Open Access

circCD151 promotes GLI2 expression by regulating miR‑30d‑5p and enhancing proliferation, invasion and stemness of lung cancer

Lihong Zhao, Hong Zheng, Ping Jiang
Article Number: 699
Published online on: 04 August 2021

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Article Open Access

Ginsenoside Re exhibits neuroprotective effects by inhibiting neuroinflammation via CAMK/MAPK/NF‑κB signaling in microglia

Iskander Madhi, Ji-Hee Kim, Ji Eun Shin, Younghee Kim
Article Number: 698
Published online on: 03 August 2021

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Article Open Access

Comparative analysis of the autism‑related variants between different autistic children in a family pedigree

Luxi Shen, Panyuan Li, Tianjin Zheng, Meichen Luo, Shao Zhang, Yuting Huang, Yongwu Hu, Hongzhi Li
Article Number: 697
Published online on: 03 August 2021

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Review Open Access

Protective effect of hydrogen sulfide on the kidney (Review)

Hu Zhang, Haitian Zhao, Nannan Guo
Article Number: 696
Published online on: 03 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑214 promotes proliferation and inhibits apoptosis via targeting Bax in nasopharyngeal carcinoma cells

Jian He, Yaoyun Tang, Yongquan Tian
Article Number: 695
Published online on: 02 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑101 induces apoptosis in cisplatin‑resistant gastric cancer cells by targeting VEGF‑C

Guangyan Li, Fang Yang, Shiyu Gu, Zhenjuan Li, Minghui Xue
Article Number: 694
Published online on: 02 August 2021

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Correction Open Access

[Corrigendum] Synergic effect between 5‑fluorouracil and celecoxib on hypoxic gastric cancer cells

Xiao-Qian Zhang, Xiu-E Sun, Wen-Dong Liu, Yu-Guang Feng, Hong-Mei Zhang, Li-Hong Shi, Xiu-Ning Sun, Yan-Qing Li, Zhi-Xing Gao
Article Number: 693
Published online on: 02 August 2021

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Article Open Access

Salidroside inhibits endothelial‑mesenchymal transition via the KLF4/eNOS signaling pathway

Yongpan Huang, Xiaodong Han, Jiayu Tang, Xian Long, Xiaoye Wang
Article Number: 692
Published online on: 01 August 2021

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Article Open Access

Atractylenolide‑1 alleviates gastroparesis in diabetic rats by activating the stem cell factor/c‑kit signaling pathway

Hui Li, Wen Cao, Xun-Bin Zhang, Xi-Xia Zhang, Chao Gu, Li-Mei Gu, Cheng-Yu Pan, Yao-Zhou Tian, Min Lu
Article Number: 691
Published online on: 01 August 2021

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Article Open Access

Heat shock protein 70 attenuates hypoxia‑induced apoptosis of pulmonary microvascular endothelial cells isolated from neonatal rats

Jing Cao, Lingjie Yang, Le Wang, Qian Zhao, Dian Wu, Mingxia Li, Yuming Mu
Article Number: 690
Published online on: 30 July 2021

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Article Open Access

miR‑351‑5p aggravates lipopolysaccharide‑induced acute lung injury via inhibiting AMPK

Fen Hu, Xianfeng Dong, Weixin Li, Jianfa Lv, Feng Lin, Gan Song, Guoqiang Hou, Ruiyun Li
Article Number: 689
Published online on: 30 July 2021

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Article Open Access

Urantide prevents CCl4‑induced acute liver injury in rats by regulating the MAPK signalling pathway

Ying Li, Zheming Guo, Haipeng Cui, Tu Wang, Yuhang Xu, Juan Zhao
Article Number: 688
Published online on: 30 July 2021

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Article

Prevention of streptozotocin‑induced Neuro‑2a cell death by C8‑B4 microglia transformed with repetitive low‑dose lipopolysaccharide

Haruka Mizobuchi, Kazushi Yamamoto, Masashi Yamashita, Hiroyuki Inagawa, Chie Kohchi, Gen-Ichiro Soma
Article Number: 687
Published online on: 30 July 2021

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Article Open Access

Liquiritigenin attenuates isoprenaline‑induced myocardial fibrosis in mice through the TGF‑β1/Smad2 and AKT/ERK signaling pathways

Li Li, Hui Fang, Yong-Hong Yu, Shan-Xin Liu, Zhi-Qiang Yang
Article Number: 686
Published online on: 30 July 2021

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Article Open Access

Galectin‑3 blockade suppresses the growth of cetuximab‑resistant human oral squamous cell carcinoma Retraction in /10.3892/mmr.2024.13275

Peng Yin, Shuanlong Cui, Xiangling Liao, Xiaoguang Yao
Article Number: 685
Published online on: 29 July 2021

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Article Open Access

Knockdown of circ‑PVT1 inhibits the progression of lung adenocarcinoma and enhances the sensitivity to cisplatin via the miR‑429/FOXK1 signaling axis

Limin Cao, Xuefeng Zhou, Xi Ding, Dongyun Gao
Article Number: 684
Published online on: 29 July 2021

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Article Open Access

miR‑214 ameliorates sepsis‑induced acute kidney injury via PTEN/AKT/mTOR‑regulated autophagy

Zhenzhen Sang, Shimin Dong, Pu Zhang, Yunxia Wei
Article Number: 683
Published online on: 29 July 2021

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Journal Cover
July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Review Open Access

Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Review Open Access

Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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Retraction Open Access

[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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Article Open Access

FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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