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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2021 Volume 24 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

miR‑101a‑3p overexpression prevents acetylcholine‑CaCl2‑induced atrial fibrillation in rats via reduction of atrial tissue fibrosis, involving inhibition of EZH2

Jing Zhu, Ning Zhu, Jian Xu
Article Number: 740
Published online on: 20 August 2021

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Article Open Access

Assessing the protective effects of cryptotanshinone on CoCl2‑induced hypoxia in RPE cells

Yu Gu, Weiming Liu, Gaoqin Liu, Xin Li, Peirong Lu
Article Number: 739
Published online on: 20 August 2021

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Article Open Access

Role of the CXCR3‑mediated TLRs/MyD88 signaling pathway in promoting the development of hepatitis B into cirrhosis and liver cancer

Gang Yuan, Bin Chen, Yina Meng, Jialin Lu, Xiaojun Shi, Airong Hu, Yaoren Hu, Donghui Wang
Article Number: 738
Published online on: 20 August 2021

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Article Open Access

Porcine pancreas mesenchymal cell characterization and functional differentiation into insulin‑producing cells in vitro

Shang Zhang, Qi Wang, Hongbing Ji, Huidi Lu, Qin Yang, Jiahui Yin, Weijun Guan
Article Number: 737
Published online on: 17 August 2021

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Article Open Access

Polyherbal formulation Anoac‑H suppresses the expression of RANTES and VEGF for the management of bleeding hemorrhoids and fistula

Ashwin Porwal, Gopal C. Kundu, Gajanan Bhagwat, Ramesh Butti
Article Number: 736
Published online on: 16 August 2021

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Article Open Access

hsa‑miR‑15a‑5p inhibits colon cell carcinoma via targeting CCND1

Zhipeng Li, Zeyu Zhu, Yanjun Wang, Ying Wang, Weibing Li, Zhigang Wang, Xinyuan Zhou, Yuhua Bao
Article Number: 735
Published online on: 16 August 2021

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Review Open Access

Roles of α‑synuclein in gastrointestinal microbiome dysbiosis‑related Parkinson's disease progression (Review)

Qingchun Lei, Tingting Wu, Jin Wu, Xiaogang Hu, Yingxia Guan, Ying Wang, Jinyuan Yan, Guolin Shi
Article Number: 734
Published online on: 16 August 2021

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Article

Intermedin1‑47 inhibits high phosphate‑induced vascular smooth muscle cell calcification by regulating Wnt/β‑catenin signaling

Yin Zhang, Naiwang Tang, Jinjie Zhou
Article Number: 733
Published online on: 16 August 2021

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Review Open Access

Theories behind the effect of starch‑ and sucrose‑reduced diets on gastrointestinal symptoms in irritable bowel syndrome (Review)

Bodil Ohlsson
Article Number: 732
Published online on: 16 August 2021

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Article Open Access

A microRNA‑17‑5p/homeobox B13 axis participates in the phenotypic modulation of vascular smooth muscle cells

Tianchi Yu, Tao Wang, Shifang Kuang, Guoping Zhao, Kun Zhou, Hui Zhang
Article Number: 731
Published online on: 16 August 2021

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Article Open Access

Ulinastatin protects against sepsis‑induced myocardial injury by inhibiting NLRP3 inflammasome activation

Juanjuan Qiu, Xiaoguang Xiao, Xue Gao, Yongli Zhang
Article Number: 730
Published online on: 16 August 2021

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Article Open Access

Reactive oxygen species induced by uric acid promote NRK‑52E cell apoptosis through the NEK7‑NLRP3 signaling pathway

Dongdong Li, Luobing Wang, Jiaoying Ou, Chuanxu Wang, Jiabao Zhou, Lili Lu, Yanshneg Wu, Jiandong Gao
Article Number: 729
Published online on: 13 August 2021

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Article Open Access

Circular RNA OMA1 regulates the progression of breast cancer via modulation of the miR‑1276/SIRT4 axis

Lingli Xu, Ke Xu, Lijun Xiang, Jiamei Yan
Article Number: 728
Published online on: 13 August 2021

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Retraction Open Access

[Retracted] Upregulation of microRNA‑27b contributes to the migration and invasion of gastric cancer cells via the inhibition of sprouty2‑mediated ERK signaling

Juan Jiang, Bo Yi, Chunxiang Qin, Siqing Ding, Wei Cao
Article Number: 727
Published online on: 13 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑145 inhibits migration and invasion via inhibition of fascin 1 protein expression in non‑small‑cell lung cancer cells

Yingying Zhang, Xucheng Yang, Haijun Wu, Weibin Zhou, Zhenzhen Liu
Article Number: 726
Published online on: 12 August 2021

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Article Open Access

Alcohol inhibits alveolar fluid clearance through the epithelial sodium channel via the A2 adenosine receptor in acute lung injury

Wang Deng, Jing He, Xu-Mao Tang, Chang-Yi Li, Jin Tong, Di Qi, Dao-Xin Wang
Article Number: 725
Published online on: 11 August 2021

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Article

MicroRNA‑25 protects nucleus pulposus cells against apoptosis via targeting SUMO2 in intervertebral disc degeneration Retraction in /10.3892/mmr.2024.13212

Changbin Lei, Jian Li, Guang Tang, Jiong Wang
Article Number: 724
Published online on: 11 August 2021

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Article Open Access

miR‑4306 inhibits the malignant behaviors of colorectal cancer by regulating lncRNA FoxD2‑AS1 Retraction in /10.3892/mmr.2024.13299

Jinjun Ye, Jidong Liu, Tao Tang, Le Xin, Xing Bao, Yukuang Yan
Article Number: 723
Published online on: 11 August 2021

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Article Open Access

HOXB13 suppresses proliferation, migration and invasion, and promotes apoptosis of gastric cancer cells through transcriptional activation of VGLL4 to inhibit the involvement of TEAD4 in the Hippo signaling pathway

Hui Geng, Guangli Liu, Jiandong Hu, Jianchao Li, Dong Wang, Shenshan Zou, Xintao Xu
Article Number: 722
Published online on: 11 August 2021

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Article Open Access

Chemosensitivity analysis and study of gene resistance on tumors and cancer stem cell isolates from patients with colorectal cancer

Elsa N. Garza‑Treviño, Herminia G. Martínez‑Rodríguez, Paulina Delgado‑González, Orlando Solís‑Coronado, Rocio Ortíz‑Lopez, Adolfo Soto‑Domínguez, Víctor M. Treviño, Gerardo R. Padilla‑Rivas, Jose F. Islas‑Cisneros, Adriana G. Quiroz‑Reyes, Salvador L. Said‑Fernández
Article Number: 721
Published online on: 11 August 2021

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Correction Open Access

[Corrigendum] Hsa‑circRNA‑G004213 promotes cisplatin sensitivity by regulating miR‑513b‑5p/PRPF39 in liver cancer

Ling Qin, Zibo Zan, Chunxue Wei, Xuemei Li, Tongqin Zhang, Jun Li
Article Number: 720
Published online on: 11 August 2021

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Article Open Access

Adiponectin inhibits D‑gal‑induced cardiomyocyte senescence via AdipoR1/APPL1

Ruiying Liu, Jing Meng, Danfei Lou
Article Number: 719
Published online on: 10 August 2021

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Article Open Access

Phylogenetic analysis of combined lobular and ductal carcinoma of the breast

Hiroko Kobayashi, Tokiko Nakai, Yoko Nakanishi, Mariko Esumi, Shinobu Masuda
Article Number: 718
Published online on: 10 August 2021

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Article

Inhibition of the p‑SPAK/p‑NKCC1 signaling pathway protects the blood‑brain barrier and reduces neuronal apoptosis in a rat model of surgical brain injury

Yating Gong, Muyao Wu, Fan Gao, Mengying Shi, Haiping Gu, Rong Gao, Bao-Qi Dang, Gang Chen
Article Number: 717
Published online on: 10 August 2021

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Article

CXCL16 may be a predisposing factor to atherosclerosis: An animal study

Junbi Zhao, Menglin Yang, Jie Wu
Article Number: 716
Published online on: 10 August 2021

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Article Open Access

Methylation profile of hepatitis B virus is not influenced by interferon α in human liver cancer cells

In Young Moon, Jin-Wook Kim
Article Number: 715
Published online on: 10 August 2021

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Review

Functional role of miR‑155 in physiological and pathological processes of liver injury (Review)

Xiao Feng, Jiaying Bao, Chunxia Song, Ling Xie, Xu Tan, Jiaqi Li, Huimin Jia, Miaomiao Tian, Jianni Qi, Chengyong Qin, Hongjun Bian
Article Number: 714
Published online on: 10 August 2021

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Article Open Access

Erastin‑induced ferroptosis causes physiological and pathological changes in healthy tissues of mice

Jing Zhao, Ben Xu, Qingqing Xiong, Yunfei Feng, Huahua Du
Article Number: 713
Published online on: 10 August 2021

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Article Open Access

Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4 Corrigendum in /10.3892/mmr.2025.13752

Yan Shi, Shu-Ai Hou
Article Number: 712
Published online on: 10 August 2021

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Article

lncRNA GAS5 regulates angiogenesis by targeting miR‑10a‑3p/VEGFA in osteoporosis

Wen Wu, Qiang Li, Yi-Feng Liu, Yong Li
Article Number: 711
Published online on: 09 August 2021

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Article Open Access

Cucurbitacin B enhances apoptosis in gefitinib resistant non‑small cell lung cancer by modulating the miR‑17‑5p/STAT3 axis

Baodan Yu, Lixia Zheng, Huiqin Tang, Weixin Wang, Yongping Lin
Article Number: 710
Published online on: 09 August 2021

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Article Open Access

Metformin inhibits cholesterol‑induced adhesion molecule expression via activating the AMPK signaling pathway in vascular smooth muscle cells

Qi Liu, Mengyue Yang, Lu Zhang, Ruoxi Zhang, Xingtao Huang, Xuedong Wang, Wenjuan Du, Jingbo Hou
Article Number: 709
Published online on: 09 August 2021

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Article Open Access

miR‑125a‑5p and miR‑7 inhibits the proliferation, migration and invasion of vascular smooth muscle cell by targeting EGFR

Hualan Zhou, Sen Lin, Youdong Hu, Dianxuan Guo, Yun Wang, Xia Li
Article Number: 708
Published online on: 09 August 2021

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Retraction Open Access

[Retracted] Effects of cyclooxygenase‑2 gene silencing on the biological behavior of SKOV3 ovarian cancer cells

Feng-Jun Guo, Jing-Yan Tian, Yue-Mei Jin, Ling Wang, Rui-Qi Yang, Man-Hua Cui
Article Number: 707
Published online on: 08 August 2021

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Review Open Access

Functional study of SCCD pathogenic gene UBIAD1 (Review)

Jumin Xie, Lingxing Li
Article Number: 706
Published online on: 06 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑144 acts as a tumor suppressor by targeting Rho‑associated coiled‑coil containing protein kinase 1 in osteosarcoma cells

Jianjun Huang, Ying Shi, Hui Li, Meisongzhu Yang, Guohong Liu
Article Number: 705
Published online on: 05 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑7 inhibits the malignant phenotypes of non‑small cell lung cancer in vitro by targeting Pax6

Jiashun Luo, Hui Li, Chunfang Zhang
Article Number: 704
Published online on: 05 August 2021

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Article

Canagliflozin is a potential cardioprotective drug but exerts no significant effects on pirarubicin‑induced cardiotoxicity in rats

Hongwei Shi, Qingfu Zeng, Yunjie Wei, Hong Yang, Heng Tang, Dan Wang, Peng Pu, Rui Feng
Article Number: 703
Published online on: 05 August 2021

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Article Open Access

Study of the pathology and the underlying molecular mechanism of tissue injury around hematoma following intracerebral hemorrhage

Jinglei Wang, Ying Chen, Jingjing Liang, Maosheng Cao, Jiabing Shen, Kaifu Ke
Article Number: 702
Published online on: 05 August 2021

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Article

Isoalantolactone alleviates ovalbumin‑induced asthmatic inflammation by reducing alternatively activated macrophage and STAT6/PPAR‑γ/KLF4 signals

Yunduan Song, Xiaozong Li, Fangfang Liu, Hongbo Zhu, Yao Shen
Article Number: 701
Published online on: 05 August 2021

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Article Open Access

Glutamate receptor, ionotropic, N‑methyl D‑aspartate‑associated protein 1 promotes colorectal cancer cell proliferation and metastasis, and is negatively regulated by miR‑296‑3p

Zaihua Yan, Peidong Li, Yuan Xue, Hongpeng Tian, Tong Zhou, Guangjun Zhang
Article Number: 700
Published online on: 04 August 2021

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Article Open Access

circCD151 promotes GLI2 expression by regulating miR‑30d‑5p and enhancing proliferation, invasion and stemness of lung cancer

Lihong Zhao, Hong Zheng, Ping Jiang
Article Number: 699
Published online on: 04 August 2021

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Article Open Access

Ginsenoside Re exhibits neuroprotective effects by inhibiting neuroinflammation via CAMK/MAPK/NF‑κB signaling in microglia

Iskander Madhi, Ji-Hee Kim, Ji Eun Shin, Younghee Kim
Article Number: 698
Published online on: 03 August 2021

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Article Open Access

Comparative analysis of the autism‑related variants between different autistic children in a family pedigree

Luxi Shen, Panyuan Li, Tianjin Zheng, Meichen Luo, Shao Zhang, Yuting Huang, Yongwu Hu, Hongzhi Li
Article Number: 697
Published online on: 03 August 2021

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Review Open Access

Protective effect of hydrogen sulfide on the kidney (Review)

Hu Zhang, Haitian Zhao, Nannan Guo
Article Number: 696
Published online on: 03 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑214 promotes proliferation and inhibits apoptosis via targeting Bax in nasopharyngeal carcinoma cells

Jian He, Yaoyun Tang, Yongquan Tian
Article Number: 695
Published online on: 02 August 2021

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Retraction Open Access

[Retracted] MicroRNA‑101 induces apoptosis in cisplatin‑resistant gastric cancer cells by targeting VEGF‑C

Guangyan Li, Fang Yang, Shiyu Gu, Zhenjuan Li, Minghui Xue
Article Number: 694
Published online on: 02 August 2021

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Correction Open Access

[Corrigendum] Synergic effect between 5‑fluorouracil and celecoxib on hypoxic gastric cancer cells

Xiao-Qian Zhang, Xiu-E Sun, Wen-Dong Liu, Yu-Guang Feng, Hong-Mei Zhang, Li-Hong Shi, Xiu-Ning Sun, Yan-Qing Li, Zhi-Xing Gao
Article Number: 693
Published online on: 02 August 2021

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Article Open Access

Salidroside inhibits endothelial‑mesenchymal transition via the KLF4/eNOS signaling pathway

Yongpan Huang, Xiaodong Han, Jiayu Tang, Xian Long, Xiaoye Wang
Article Number: 692
Published online on: 01 August 2021

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Article Open Access

Atractylenolide‑1 alleviates gastroparesis in diabetic rats by activating the stem cell factor/c‑kit signaling pathway

Hui Li, Wen Cao, Xun-Bin Zhang, Xi-Xia Zhang, Chao Gu, Li-Mei Gu, Cheng-Yu Pan, Yao-Zhou Tian, Min Lu
Article Number: 691
Published online on: 01 August 2021

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Article Open Access

Heat shock protein 70 attenuates hypoxia‑induced apoptosis of pulmonary microvascular endothelial cells isolated from neonatal rats

Jing Cao, Lingjie Yang, Le Wang, Qian Zhao, Dian Wu, Mingxia Li, Yuming Mu
Article Number: 690
Published online on: 30 July 2021

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Article Open Access

miR‑351‑5p aggravates lipopolysaccharide‑induced acute lung injury via inhibiting AMPK

Fen Hu, Xianfeng Dong, Weixin Li, Jianfa Lv, Feng Lin, Gan Song, Guoqiang Hou, Ruiyun Li
Article Number: 689
Published online on: 30 July 2021

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Article Open Access

Urantide prevents CCl4‑induced acute liver injury in rats by regulating the MAPK signalling pathway

Ying Li, Zheming Guo, Haipeng Cui, Tu Wang, Yuhang Xu, Juan Zhao
Article Number: 688
Published online on: 30 July 2021

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Article

Prevention of streptozotocin‑induced Neuro‑2a cell death by C8‑B4 microglia transformed with repetitive low‑dose lipopolysaccharide

Haruka Mizobuchi, Kazushi Yamamoto, Masashi Yamashita, Hiroyuki Inagawa, Chie Kohchi, Gen-Ichiro Soma
Article Number: 687
Published online on: 30 July 2021

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Article Open Access

Liquiritigenin attenuates isoprenaline‑induced myocardial fibrosis in mice through the TGF‑β1/Smad2 and AKT/ERK signaling pathways

Li Li, Hui Fang, Yong-Hong Yu, Shan-Xin Liu, Zhi-Qiang Yang
Article Number: 686
Published online on: 30 July 2021

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Article Open Access

Galectin‑3 blockade suppresses the growth of cetuximab‑resistant human oral squamous cell carcinoma Retraction in /10.3892/mmr.2024.13275

Peng Yin, Shuanlong Cui, Xiangling Liao, Xiaoguang Yao
Article Number: 685
Published online on: 29 July 2021

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Article Open Access

Knockdown of circ‑PVT1 inhibits the progression of lung adenocarcinoma and enhances the sensitivity to cisplatin via the miR‑429/FOXK1 signaling axis

Limin Cao, Xuefeng Zhou, Xi Ding, Dongyun Gao
Article Number: 684
Published online on: 29 July 2021

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Article Open Access

miR‑214 ameliorates sepsis‑induced acute kidney injury via PTEN/AKT/mTOR‑regulated autophagy

Zhenzhen Sang, Shimin Dong, Pu Zhang, Yunxia Wei
Article Number: 683
Published online on: 29 July 2021

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
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Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Article Number: 33
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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

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Published online on: 03 November 2025

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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Article Number: 25
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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

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Published online on: 29 October 2025

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Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

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Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

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Article Number: 18
Published online on: 29 October 2025

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Published online on: 29 October 2025

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Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

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Article Number: 15
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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

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Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

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Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

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Published online on: 22 October 2025

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Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

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Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

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SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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