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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2021 Volume 24 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Distinct effects of different doses of kaempferol on D‑GalN/LPS‑induced ALF depend on the autophagy pathway

Yuan Tian, Feng Ren, Ling Xu, Xiangying Zhang
Article Number: 682
Published online on: 27 July 2021

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Article

Senescent RAW264.7 cells exhibit increased production of nitric oxide and release inducible nitric oxide synthase in exosomes

Hirokazu Hattori, Kazuki Takaoka, Miho Ueta, Masayuki Oshitani, Joji Tamaoka, Kazuma Noguchi, Hiromitsu Kishimoto
Article Number: 681
Published online on: 27 July 2021

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Review

Effects of calcium‑permeable ion channels on various digestive diseases in the regulation of autophagy (Review)

Jun Lou, Xiaoxu Yang, Weixi Shan, Zhe Jin, Jianhong Ding, Yanxia Hu, Qiushi Liao, Qian Du, Rui Xie, Jingyu Xu
Article Number: 680
Published online on: 26 July 2021

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Retraction Open Access

[Retracted] Talen‑mediated girdin knockout downregulates cell proliferation, migration and invasion in human esophageal carcinoma ECA109 cells

Ke Cao, Wenting Jiang, Peiguo Cao, Qiong Zou, Sheng Xiao, Jianda Zhou, Chenghui Huang
Article Number: 679
Published online on: 23 July 2021

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Article

Preliminary results of targeted sequencing of BRCA1 and BRCA2 in a cohort of breast cancer families: New insight into pathogenic variants in patients and at‑risk relatives

Marwa H. Saied, Dalal Elkaffash, Reham Fadl, Reham Abdel Haleem, Amal Refeat, Inas Ibrahim, Mona Tahoun, Alyaa Elkayal, Eman Tayae
Article Number: 678
Published online on: 23 July 2021

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Review Open Access

Claudin 6: Therapeutic prospects for tumours, and mechanisms of expression and regulation (Review)

Huan Du, Xiyue Yang, Jinjia Fan, Xiaobo Du
Article Number: 677
Published online on: 23 July 2021

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Article Open Access

Sacubitril/valsartan (LCZ696) reduces myocardial injury following myocardial infarction by inhibiting NLRP3‑induced pyroptosis via the TAK1/JNK signaling pathway

Jianfen Shen, Zhongbao Fan, Guang Sun, Guoxian Qi
Article Number: 676
Published online on: 23 July 2021

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Article Open Access

miR‑140‑5p alleviates mouse liver ischemia/reperfusion injury by targeting CAPN1

Qiwen Yu, Sanyang Chen, Hongwei Tang, Han Yang, Jiakai Zhang, Xiaoyi Shi, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 675
Published online on: 22 July 2021

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Article Open Access

Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner

Wen-Juan Wang, Xia Jiang, Chang-Chun Gao, Zhi-Wei Chen
Article Number: 674
Published online on: 22 July 2021

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Correction Open Access

[Corrigendum] miR‑592 acts as an oncogene and promotes medullary thyroid cancer tumorigenesis by targeting cyclin‑dependent kinase 8

Ting Liu, Jingjing Meng, Yu Zhang
Article Number: 673
Published online on: 22 July 2021

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Article Open Access

Dimethyl itaconate inhibits LPS‑induced microglia inflammation and inflammasome‑mediated pyroptosis via inducing autophagy and regulating the Nrf‑2/HO‑1 signaling pathway

Su Yang, Xingxing Zhang, Hengli Zhang, Xiangxiang Lin, Xijun Chen, Ying Zhang, Xiao Lin, Lijie Huang, Qichuan Zhuge
Article Number: 672
Published online on: 21 July 2021

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Article Open Access

SOD2 overexpression in bone marrow‑derived mesenchymal stem cells ameliorates hepatic ischemia/reperfusion injury

Qiuyun Li, Wei Zhang, Enhua Xiao
Article Number: 671
Published online on: 21 July 2021

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Retraction Open Access

[Retracted] Small interfering RNA‑induced silencing of galectin‑3 inhibits the malignant phenotypes of osteosarcoma in vitro

Pengfei Lei, Hongbo He, Yihe Hu, Zhan Liao
Article Number: 670
Published online on: 21 July 2021

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Correction Open Access

[Corrigendum] Novel markers of human ovarian granulosa cell differentiation toward osteoblast lineage: A microarray approach

Maciej Brązert, Wiesława Kranc, Piotr Celichowski, Katarzyna Ożegowska, Joanna Budna‑Tukan, Michal Jeseta, Leszek Pawelczyk, Małgorzata Bruska, Maciej Zabel, Michał Nowicki, Bartosz Kempisty
Article Number: 669
Published online on: 21 July 2021

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Article Open Access

Transcriptional activation of ENPP2 by FoxO4 protects cardiomyocytes from doxorubicin‑induced toxicity

Ling He, Yuting Yang, Juan Chen, Pengtao Zou, Juxiang Li
Article Number: 668
Published online on: 20 July 2021

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Article Open Access

Upregulation of miR‑128 inhibits neuronal cell apoptosis following spinal cord injury via FasL downregulation by repressing ULK1

Ruixuan Liu, Zhibin Peng, Yubo Zhang, Rui Li, Yansong Wang
Article Number: 667
Published online on: 20 July 2021

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Article Open Access

MicroRNA‑93 inhibits the apoptosis and inflammatory response of tubular epithelial cells via the PTEN/AKT/mTOR pathway in acute kidney injury

Yaping Zhan, Minxia Zhu, Shang Liu, Jiayue Lu, Zhaohui Ni, Hong Cai, Weiming Zhang
Article Number: 666
Published online on: 20 July 2021

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Article

Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress‑impaired endothelial cell angiogenic response: A critical role for cell survival

Shahenda S. Abdelsalam, Mazhar Pasha, Heba El‑Gamal, Maram Hasan, Mohamed A. Elrayess, Asad Zeidan, Hesham M. Korashy, Abdelali Agouni
Article Number: 665
Published online on: 20 July 2021

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Article

miR‑34a increases inflammation and oxidative stress levels in patients with necrotizing enterocolitis by downregulating SIRT1 expression

Hui Zhu, Yan Lin, Yongle Liu
Article Number: 664
Published online on: 20 July 2021

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Review Open Access

Ghrelin and its role in gastrointestinal tract tumors (Review)

Irene Alexandra Spiridon, Delia Gabriela Apostol Ciobanu, Simona Eliza Giușcă, Irina Draga Căruntu
Article Number: 663
Published online on: 19 July 2021

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Article

Effect of intestinal microbiota imbalance associated with chronic hepatitis B virus infection on the expression of microRNA‑192 and GLP‑1

Yinghui Liu
Article Number: 662
Published online on: 19 July 2021

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Article Open Access

Dexmedetomidine alleviates early brain injury following traumatic brain injury by inhibiting autophagy and neuroinflammation through the ROS/Nrf2 signaling pathway

Xiaoyan Feng, Weiwei Ma, Jie Zhu, Wei Jiao, Yuhai Wang
Article Number: 661
Published online on: 18 July 2021

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Retraction Open Access

[Retracted] PAX6, a novel target of miR-335, inhibits cell proliferation and invasion in glioma cells

Quan Cheng, Hui Cao, Zigui Chen, Zhiming Ma, Xin Wan, Renjun Peng, Bing Jiang
Article Number: 660
Published online on: 16 July 2021

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Retraction Open Access

[Retracted] MicroRNA‑148a inhibits migration and invasion of ovarian cancer cells via targeting sphingosine‑1‑phosphate receptor 1

Zhengfang Wen, Shuzhen Zhao, Shanshan Liu, Ying Liu, Xiaorui Li, Shaoru Li
Article Number: 659
Published online on: 15 July 2021

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Article

Tacrolimus inhibits insulin release and promotes apoptosis of Min6 cells through the inhibition of the PI3K/Akt/mTOR pathway

Ling Tong, Weiliang Li, Ying Zhang, Fan Zhou, Yan Zhao, Linlin Zhao, Jing Liu, Zhirui Song, Mengchen Yu, Chengrui Zhou, Airong Yu
Article Number: 658
Published online on: 15 July 2021

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Article Open Access

Blockage of Drp1 phosphorylation at Ser579 protects neurons against Aβ1‑42‑induced degeneration

Dan Xu, Ping Yang, Zhang-Jian Yang, Qiu-Gen Li, Ye-Tong Ouyang, Ting Yu, Jian-Hui Shangguan, Yu-Ying Wan, Li-Ping Jiang, Xin-Hui Qu, Xiao-Jian Han
Article Number: 657
Published online on: 15 July 2021

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Correction Open Access

[Corrigendum] Integrated transcriptomic and epigenetic data analysis identifies aberrant expression of genes in acute myeloid leukemia with MLL‑AF9 translocation

Fangce Wang, Zheng Li, Guangming Wang, Xiaoxue Tian, Jie Zhou, Wenlei Yu, Zhuoyi Fan, Lin Dong, Jinyuan Lu, Jun Xu, Wenjun Zhang, Aibin Liang
Article Number: 656
Published online on: 15 July 2021

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Retraction Open Access

[Retracted] MicroRNA‑148a inhibits the proliferation and promotes the paclitaxel‑induced apoptosis of ovarian cancer cells by targeting PDIA3

Shuzhen Zhao, Zhengfang Wen, Shanshan Liu, Ying Liu, Xiaorui Li, Yanna Ge, Shaoru Li
Article Number: 655
Published online on: 14 July 2021

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Article Open Access

hsa_circ_0101119 facilitates the progression of cervical cancer via an interaction with EIF4A3 to inhibit TCEAL6 expression

Xuezuo Sui, Yanchun Wang, Hui Liu
Article Number: 654
Published online on: 14 July 2021

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Article Open Access

Protective effect of taurine on sepsis‑induced lung injury via inhibiting the p38/MAPK signaling pathway

Jiao Chen, Xiang Xue, Jianqin Cai, Ling Jia, Baodi Sun, Wei Zhao
Article Number: 653
Published online on: 14 July 2021

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Article Open Access

Psoralen inhibits the inflammatory response and mucus production in allergic rhinitis by inhibiting the activator protein 1 pathway and the downstream expression of cystatin‑SN

Wenying Gao, Zhenglong Jin, Yanxia Zheng, Youjia Xu
Article Number: 652
Published online on: 14 July 2021

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Article Open Access

FOXG1 improves mitochondrial function and promotes the progression of nasopharyngeal carcinoma

Huajun Xi, Zhengxiang He, Cao Lv
Article Number: 651
Published online on: 14 July 2021

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Article Open Access

Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma

Ke Zhan, Yang Bai, Shengtao Liao, Hongyu Chen, Lili Kuang, Qingqing Luo, Lin Lv, Liewang Qiu, Zhechuan Mei
Article Number: 650
Published online on: 13 July 2021

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Article

Long non‑coding RNA DANCR represses the viability, migration and invasion of multiple myeloma cells by sponging miR‑135b‑5p to target KLF9

Linlin Wu, Liang Xia, Huimin Jiang, Yue Hu, Lingling Li, Li Xu, Ruixiang Xia
Article Number: 649
Published online on: 13 July 2021

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Review Open Access

Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review)

Qingtao Zhang, Jian Yu, Qiuqiu Chen, Honghai Yan, Hongjiang Du, Wenjing Luo
Article Number: 648
Published online on: 13 July 2021

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Article Open Access

FBXL19‑AS1 promotes the progression of nasopharyngeal carcinoma by acting as a competing endogenous RNA to sponge miR‑431 and upregulate PBOV1

Hongjun Dong, Chao Huang, Jingjing Huang
Article Number: 647
Published online on: 12 July 2021

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Article Open Access

Map of dimorphic switching‑related signaling pathways in Sporothrix schenckii based on its transcriptome

Fangliang Zheng, Wei Gao, Ying Wang, Qingyan Chen, Qiuling Zhang, Xiuyan Jiang, Binbin Hou, Zhenying Zhang
Article Number: 646
Published online on: 12 July 2021

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Article

Asiaticoside reduces autophagy and improves memory in a rat model of dementia through mTOR signaling pathway regulation

Min Guo, Jianmeng Xu, Shiwei Wang, Baohua Dong
Article Number: 645
Published online on: 12 July 2021

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Correction Open Access

[Corrigendum] Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells

Sumiyasuren Buyanravjikh, Sora Han, Sunyi Lee, Ae Lee Jeong, Hye In Ka, Ji Young Park, Ariundavaa Boldbaatar, Jong-Seok Lim, Myeong-Sok Lee, Young Yang
Article Number: 644
Published online on: 12 July 2021

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Article

Lycium barbarum polysaccharides attenuate cardiovascular oxidative stress injury by enhancing the Keap1/Nrf2 signaling pathway in exhaustive exercise rats

Xiaohui Hu, Le Mu, Lingqin Zhu, Xiaoyu Chang, Lihong Nie, Li Wang, Guanghua Li
Article Number: 643
Published online on: 11 July 2021

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Article Open Access

Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro

Nian Zhou, Bing Yan, Jing Ma, Hongchao Jiang, Li Li, Haoyu Tang, Fengming Ji, Zhigang Yao
Article Number: 642
Published online on: 11 July 2021

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Retraction Open Access

[Retracted] miR‑22 inhibits proliferation and invasion in estrogen receptor α‑positive endometrial endometrioid carcinomas cells

Shaoru Li, Ruili Hu, Chuanhong Wang, Fang Guo, Xiaoli Li, Shijin Wang
Article Number: 641
Published online on: 09 July 2021

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Retraction Open Access

[Retracted] microRNA‑206 overexpression inhibits cellular proliferation and invasion of estrogen receptor α‑positive ovarian cancer cells

Shaoru Li, Yan Li, Zhengfang Wen, Fanjing Kong, Xinlei Guan, Wenhui Liu
Article Number: 640
Published online on: 09 July 2021

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Retraction Open Access

[Retracted] microRNA‑335 inhibits proliferation, cell‑cycle progression, colony formation, and invasion via targeting PAX6 in breast cancer cells

Yuanbiao Meng, Quanqing Zou, Tianqi Liu, Xiaoyong Cai, Yubin Huang, Jinfei Pan
Article Number: 639
Published online on: 09 July 2021

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Article Open Access

Cinnamaldehyde inhibits psoriasis‑like inflammation by suppressing proliferation and inflammatory response of keratinocytes via inhibition of NF‑κB and JNK signaling pathways

Zhenzhen Ding, Jingjing Liu, Huangjing Qian, Lingjian Wu, Mingfen Lv
Article Number: 638
Published online on: 07 July 2021

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Article Open Access

Hypoxia‑induced lactate dehydrogenase A protects cells from apoptosis in endometriosis

Jinyan Zheng, Yongdong Dai, Xiang Lin, Qianmeng Huang, Libing Shi, Xiaoying Jin, Na Liu, Feng Zhou, Songying Zhang
Article Number: 637
Published online on: 06 July 2021

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Article Open Access

Interactions between the ERK1/2 signaling pathway and PCAF play a key role in PE‑induced cardiomyocyte hypertrophy

Qian Mao, Shuqi Wu, Chang Peng, Bohui Peng, Xiaomei Luo, Lixin Huang, Huanting Zhang
Article Number: 636
Published online on: 06 July 2021

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Article Open Access

Chemokine CCL20 promotes the paclitaxel resistance of CD44+CD117+ cells via the Notch1 signaling pathway in ovarian cancer

Min Chen, Juan Su, Chunmei Feng, Ying Liu, Li Zhao, Yongjie Tian
Article Number: 635
Published online on: 06 July 2021

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Article Open Access

Sirt3 promotes the autophagy of HK‑2 human proximal tubular epithelial cells via the inhibition of Notch‑1/Hes‑1 signaling

Ying Wang, Jiang Chang, Zi-Qiang Wang, Ying Li
Article Number: 634
Published online on: 06 July 2021

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Article Open Access

miR‑3613‑3p/MAP3K2/p38/caspase‑3 pathway regulates the heat‑stress‑induced apoptosis of endothelial cells

Jie Liu, Siya Xu, Shixin Liu, Bingguan Chen
Article Number: 633
Published online on: 06 July 2021

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Article Open Access

ZIC2 upregulates lncRNA SNHG12 expression to promote endometrial cancer cell proliferation and migration by activating the Notch signaling pathway

Pengyu Cai, Gaijuan Li, Mingxiu Wu, Bin Zhang, Hong Bai
Article Number: 632
Published online on: 05 July 2021

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Article Open Access

Whole‑genome identification and systematic analysis of lncRNA‑mRNA co‑expression profiles in patients with cutaneous basal cell carcinoma

Jiaan Zhang, Xuyue Zhou, Chenpu Zhu, Yu Hu, Rong Li, Shuang Jin, Dan Huang, Mei Ju, Kun Chen, Chao Luan
Article Number: 631
Published online on: 05 July 2021

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Review

Chloride intracellular channels as novel biomarkers for digestive system tumors (Review)

Hui Wang, Jiaxing An, Suyu He, Chengcheng Liao, Juan Wang, Biguang Tuo
Article Number: 630
Published online on: 05 July 2021

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Article Open Access

Oxaliplatin promotes siMAD2L2‑induced apoptosis in colon cancer cells

Lu Ma, Xin Li, Xiaopeng Zhao, Haotong Sun, Feifei Kong, Yuanjie Li, Yu Sui, Fang Xu
Article Number: 629
Published online on: 05 July 2021

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Correction Open Access

[Corrigendum] Lentivirus‑mediated RNA interference of clusterin enhances the chemosensitivity of EJ bladder cancer cells to epirubicin in vitro

Jian Lu, Jun-Hang Luo, Jian Pang, Jia-Zheng Cao, Rong-Hai Wu, Zhu-Ting Tong, Wei Chen, Dan Xie
Article Number: 628
Published online on: 01 July 2021

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Article Open Access

MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch

Yushi Cao, Zhongwen Cao, Weitie Wang, Xiangyu Jie, Lei Li
Article Number: 627
Published online on: 01 July 2021

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Correction Open Access

[Erratum] Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells (Review)

Ying Li, Jinming Wang, Weiliang Zhong
Article Number: 626
Published online on: 30 June 2021

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Article Open Access

Differences in TNF‑α and TNF‑R1 expression in damaged neurons and activated astrocytes of the hippocampal CA1 region between young and adult gerbils following transient forebrain ischemia

Choong Hyun Lee, Ji Hyeon Ahn, Bai Hui Chen, Dae Won Kim, Hyejin Sim, Tae-Kyeong Lee, Joon Ha Park, Moo-Ho Won, Soo Young Choi
Article Number: 625
Published online on: 30 June 2021

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Article Open Access

Effect of Tongfu Xingshen capsule on the endogenous neural stem cells of experimental rats with intracerebral hemorrhage

Zhizhong Cui, Shanshan Liu, Lingbo Hou, Yifan Sun, Haoxuan Chen, Hui Mao, Yuanqi Zhao, Lijun Qiao
Article Number: 624
Published online on: 30 June 2021

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Article Open Access

Inhibitory effect of gefitinib derivative LPY‑9 on human glioma

Yuchen Sun, Liangzhao Chu, Huijuan Wang, Han Peng, Jian Liu
Article Number: 623
Published online on: 30 June 2021

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Article Open Access

Interference with KCNJ2 inhibits proliferation, migration and EMT progression of apillary thyroid carcinoma cells by upregulating GNG2 expression

Siyuan Chen, Miaoming Huang, Xiarong Hu
Article Number: 622
Published online on: 30 June 2021

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Article Open Access

Protective effects of the knockdown of lncRNA AK139328 against oxygen glucose deprivation/reoxygenation-induced injury in PC12 cells

Liyan Liu, Bin Zheng, Zhaoxia Wang
Article Number: 621
Published online on: 30 June 2021

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Correction Open Access

[Corrigendum] 20(s)‑ginseonside‑Rg3 modulation of AMPK/FoxO3 signaling to attenuate mitochondrial dysfunction in a dexamethasone‑injured C2C12 myotube‑based model of skeletal atrophy in vitro

Manying Wang, Rui Jiang, Jianzeng Liu, Xiaohao Xu, Guang Sun, Daqing Zhao, Liwei Sun
Article Number: 620
Published online on: 30 June 2021

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Long non‑coding RNA HOTTIP enhances the fibrosis of lung tissues by regulating the miR‑744‑5p/PTBP1 signaling axis

Jing Li, Wenshu Chai, Zhuo Zhao, Yan Zhou, Qi Wu
Article Number: 619
Published online on: 30 June 2021

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July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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