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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2021 Volume 24 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Distinct effects of different doses of kaempferol on D‑GalN/LPS‑induced ALF depend on the autophagy pathway

Yuan Tian, Feng Ren, Ling Xu, Xiangying Zhang
Article Number: 682
Published online on: 27 July 2021

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Article

Senescent RAW264.7 cells exhibit increased production of nitric oxide and release inducible nitric oxide synthase in exosomes

Hirokazu Hattori, Kazuki Takaoka, Miho Ueta, Masayuki Oshitani, Joji Tamaoka, Kazuma Noguchi, Hiromitsu Kishimoto
Article Number: 681
Published online on: 27 July 2021

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Review

Effects of calcium‑permeable ion channels on various digestive diseases in the regulation of autophagy (Review)

Jun Lou, Xiaoxu Yang, Weixi Shan, Zhe Jin, Jianhong Ding, Yanxia Hu, Qiushi Liao, Qian Du, Rui Xie, Jingyu Xu
Article Number: 680
Published online on: 26 July 2021

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Retraction Open Access

[Retracted] Talen‑mediated girdin knockout downregulates cell proliferation, migration and invasion in human esophageal carcinoma ECA109 cells

Ke Cao, Wenting Jiang, Peiguo Cao, Qiong Zou, Sheng Xiao, Jianda Zhou, Chenghui Huang
Article Number: 679
Published online on: 23 July 2021

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Article

Preliminary results of targeted sequencing of BRCA1 and BRCA2 in a cohort of breast cancer families: New insight into pathogenic variants in patients and at‑risk relatives

Marwa H. Saied, Dalal Elkaffash, Reham Fadl, Reham Abdel Haleem, Amal Refeat, Inas Ibrahim, Mona Tahoun, Alyaa Elkayal, Eman Tayae
Article Number: 678
Published online on: 23 July 2021

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Review Open Access

Claudin 6: Therapeutic prospects for tumours, and mechanisms of expression and regulation (Review)

Huan Du, Xiyue Yang, Jinjia Fan, Xiaobo Du
Article Number: 677
Published online on: 23 July 2021

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Article Open Access

Sacubitril/valsartan (LCZ696) reduces myocardial injury following myocardial infarction by inhibiting NLRP3‑induced pyroptosis via the TAK1/JNK signaling pathway

Jianfen Shen, Zhongbao Fan, Guang Sun, Guoxian Qi
Article Number: 676
Published online on: 23 July 2021

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Article Open Access

miR‑140‑5p alleviates mouse liver ischemia/reperfusion injury by targeting CAPN1

Qiwen Yu, Sanyang Chen, Hongwei Tang, Han Yang, Jiakai Zhang, Xiaoyi Shi, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 675
Published online on: 22 July 2021

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Article Open Access

Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner

Wen-Juan Wang, Xia Jiang, Chang-Chun Gao, Zhi-Wei Chen
Article Number: 674
Published online on: 22 July 2021

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Correction Open Access

[Corrigendum] miR‑592 acts as an oncogene and promotes medullary thyroid cancer tumorigenesis by targeting cyclin‑dependent kinase 8

Ting Liu, Jingjing Meng, Yu Zhang
Article Number: 673
Published online on: 22 July 2021

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Article Open Access

Dimethyl itaconate inhibits LPS‑induced microglia inflammation and inflammasome‑mediated pyroptosis via inducing autophagy and regulating the Nrf‑2/HO‑1 signaling pathway

Su Yang, Xingxing Zhang, Hengli Zhang, Xiangxiang Lin, Xijun Chen, Ying Zhang, Xiao Lin, Lijie Huang, Qichuan Zhuge
Article Number: 672
Published online on: 21 July 2021

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Article Open Access

SOD2 overexpression in bone marrow‑derived mesenchymal stem cells ameliorates hepatic ischemia/reperfusion injury

Qiuyun Li, Wei Zhang, Enhua Xiao
Article Number: 671
Published online on: 21 July 2021

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Retraction Open Access

[Retracted] Small interfering RNA‑induced silencing of galectin‑3 inhibits the malignant phenotypes of osteosarcoma in vitro

Pengfei Lei, Hongbo He, Yihe Hu, Zhan Liao
Article Number: 670
Published online on: 21 July 2021

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Correction Open Access

[Corrigendum] Novel markers of human ovarian granulosa cell differentiation toward osteoblast lineage: A microarray approach

Maciej Brązert, Wiesława Kranc, Piotr Celichowski, Katarzyna Ożegowska, Joanna Budna‑Tukan, Michal Jeseta, Leszek Pawelczyk, Małgorzata Bruska, Maciej Zabel, Michał Nowicki, Bartosz Kempisty
Article Number: 669
Published online on: 21 July 2021

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Article Open Access

Transcriptional activation of ENPP2 by FoxO4 protects cardiomyocytes from doxorubicin‑induced toxicity

Ling He, Yuting Yang, Juan Chen, Pengtao Zou, Juxiang Li
Article Number: 668
Published online on: 20 July 2021

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Article Open Access

Upregulation of miR‑128 inhibits neuronal cell apoptosis following spinal cord injury via FasL downregulation by repressing ULK1

Ruixuan Liu, Zhibin Peng, Yubo Zhang, Rui Li, Yansong Wang
Article Number: 667
Published online on: 20 July 2021

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Article Open Access

MicroRNA‑93 inhibits the apoptosis and inflammatory response of tubular epithelial cells via the PTEN/AKT/mTOR pathway in acute kidney injury

Yaping Zhan, Minxia Zhu, Shang Liu, Jiayue Lu, Zhaohui Ni, Hong Cai, Weiming Zhang
Article Number: 666
Published online on: 20 July 2021

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Article

Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress‑impaired endothelial cell angiogenic response: A critical role for cell survival

Shahenda S. Abdelsalam, Mazhar Pasha, Heba El‑Gamal, Maram Hasan, Mohamed A. Elrayess, Asad Zeidan, Hesham M. Korashy, Abdelali Agouni
Article Number: 665
Published online on: 20 July 2021

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Article

miR‑34a increases inflammation and oxidative stress levels in patients with necrotizing enterocolitis by downregulating SIRT1 expression

Hui Zhu, Yan Lin, Yongle Liu
Article Number: 664
Published online on: 20 July 2021

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Review Open Access

Ghrelin and its role in gastrointestinal tract tumors (Review)

Irene Alexandra Spiridon, Delia Gabriela Apostol Ciobanu, Simona Eliza Giușcă, Irina Draga Căruntu
Article Number: 663
Published online on: 19 July 2021

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Article

Effect of intestinal microbiota imbalance associated with chronic hepatitis B virus infection on the expression of microRNA‑192 and GLP‑1

Yinghui Liu
Article Number: 662
Published online on: 19 July 2021

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Article Open Access

Dexmedetomidine alleviates early brain injury following traumatic brain injury by inhibiting autophagy and neuroinflammation through the ROS/Nrf2 signaling pathway

Xiaoyan Feng, Weiwei Ma, Jie Zhu, Wei Jiao, Yuhai Wang
Article Number: 661
Published online on: 18 July 2021

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Retraction Open Access

[Retracted] PAX6, a novel target of miR-335, inhibits cell proliferation and invasion in glioma cells

Quan Cheng, Hui Cao, Zigui Chen, Zhiming Ma, Xin Wan, Renjun Peng, Bing Jiang
Article Number: 660
Published online on: 16 July 2021

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Retraction Open Access

[Retracted] MicroRNA‑148a inhibits migration and invasion of ovarian cancer cells via targeting sphingosine‑1‑phosphate receptor 1

Zhengfang Wen, Shuzhen Zhao, Shanshan Liu, Ying Liu, Xiaorui Li, Shaoru Li
Article Number: 659
Published online on: 15 July 2021

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Article

Tacrolimus inhibits insulin release and promotes apoptosis of Min6 cells through the inhibition of the PI3K/Akt/mTOR pathway

Ling Tong, Weiliang Li, Ying Zhang, Fan Zhou, Yan Zhao, Linlin Zhao, Jing Liu, Zhirui Song, Mengchen Yu, Chengrui Zhou, Airong Yu
Article Number: 658
Published online on: 15 July 2021

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Article Open Access

Blockage of Drp1 phosphorylation at Ser579 protects neurons against Aβ1‑42‑induced degeneration

Dan Xu, Ping Yang, Zhang-Jian Yang, Qiu-Gen Li, Ye-Tong Ouyang, Ting Yu, Jian-Hui Shangguan, Yu-Ying Wan, Li-Ping Jiang, Xin-Hui Qu, Xiao-Jian Han
Article Number: 657
Published online on: 15 July 2021

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Correction Open Access

[Corrigendum] Integrated transcriptomic and epigenetic data analysis identifies aberrant expression of genes in acute myeloid leukemia with MLL‑AF9 translocation

Fangce Wang, Zheng Li, Guangming Wang, Xiaoxue Tian, Jie Zhou, Wenlei Yu, Zhuoyi Fan, Lin Dong, Jinyuan Lu, Jun Xu, Wenjun Zhang, Aibin Liang
Article Number: 656
Published online on: 15 July 2021

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Retraction Open Access

[Retracted] MicroRNA‑148a inhibits the proliferation and promotes the paclitaxel‑induced apoptosis of ovarian cancer cells by targeting PDIA3

Shuzhen Zhao, Zhengfang Wen, Shanshan Liu, Ying Liu, Xiaorui Li, Yanna Ge, Shaoru Li
Article Number: 655
Published online on: 14 July 2021

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Article Open Access

hsa_circ_0101119 facilitates the progression of cervical cancer via an interaction with EIF4A3 to inhibit TCEAL6 expression

Xuezuo Sui, Yanchun Wang, Hui Liu
Article Number: 654
Published online on: 14 July 2021

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Article Open Access

Protective effect of taurine on sepsis‑induced lung injury via inhibiting the p38/MAPK signaling pathway

Jiao Chen, Xiang Xue, Jianqin Cai, Ling Jia, Baodi Sun, Wei Zhao
Article Number: 653
Published online on: 14 July 2021

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Article Open Access

Psoralen inhibits the inflammatory response and mucus production in allergic rhinitis by inhibiting the activator protein 1 pathway and the downstream expression of cystatin‑SN

Wenying Gao, Zhenglong Jin, Yanxia Zheng, Youjia Xu
Article Number: 652
Published online on: 14 July 2021

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Article Open Access

FOXG1 improves mitochondrial function and promotes the progression of nasopharyngeal carcinoma

Huajun Xi, Zhengxiang He, Cao Lv
Article Number: 651
Published online on: 14 July 2021

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Article Open Access

Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma

Ke Zhan, Yang Bai, Shengtao Liao, Hongyu Chen, Lili Kuang, Qingqing Luo, Lin Lv, Liewang Qiu, Zhechuan Mei
Article Number: 650
Published online on: 13 July 2021

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Article

Long non‑coding RNA DANCR represses the viability, migration and invasion of multiple myeloma cells by sponging miR‑135b‑5p to target KLF9

Linlin Wu, Liang Xia, Huimin Jiang, Yue Hu, Lingling Li, Li Xu, Ruixiang Xia
Article Number: 649
Published online on: 13 July 2021

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Review Open Access

Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review)

Qingtao Zhang, Jian Yu, Qiuqiu Chen, Honghai Yan, Hongjiang Du, Wenjing Luo
Article Number: 648
Published online on: 13 July 2021

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Article Open Access

FBXL19‑AS1 promotes the progression of nasopharyngeal carcinoma by acting as a competing endogenous RNA to sponge miR‑431 and upregulate PBOV1

Hongjun Dong, Chao Huang, Jingjing Huang
Article Number: 647
Published online on: 12 July 2021

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Article Open Access

Map of dimorphic switching‑related signaling pathways in Sporothrix schenckii based on its transcriptome

Fangliang Zheng, Wei Gao, Ying Wang, Qingyan Chen, Qiuling Zhang, Xiuyan Jiang, Binbin Hou, Zhenying Zhang
Article Number: 646
Published online on: 12 July 2021

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Article

Asiaticoside reduces autophagy and improves memory in a rat model of dementia through mTOR signaling pathway regulation

Min Guo, Jianmeng Xu, Shiwei Wang, Baohua Dong
Article Number: 645
Published online on: 12 July 2021

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Correction Open Access

[Corrigendum] Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells

Sumiyasuren Buyanravjikh, Sora Han, Sunyi Lee, Ae Lee Jeong, Hye In Ka, Ji Young Park, Ariundavaa Boldbaatar, Jong-Seok Lim, Myeong-Sok Lee, Young Yang
Article Number: 644
Published online on: 12 July 2021

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Article

Lycium barbarum polysaccharides attenuate cardiovascular oxidative stress injury by enhancing the Keap1/Nrf2 signaling pathway in exhaustive exercise rats

Xiaohui Hu, Le Mu, Lingqin Zhu, Xiaoyu Chang, Lihong Nie, Li Wang, Guanghua Li
Article Number: 643
Published online on: 11 July 2021

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Article Open Access

Expression of TCF3 in Wilms' tumor and its regulatory role in kidney tumor cell viability, migration and apoptosis in vitro

Nian Zhou, Bing Yan, Jing Ma, Hongchao Jiang, Li Li, Haoyu Tang, Fengming Ji, Zhigang Yao
Article Number: 642
Published online on: 11 July 2021

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Retraction Open Access

[Retracted] miR‑22 inhibits proliferation and invasion in estrogen receptor α‑positive endometrial endometrioid carcinomas cells

Shaoru Li, Ruili Hu, Chuanhong Wang, Fang Guo, Xiaoli Li, Shijin Wang
Article Number: 641
Published online on: 09 July 2021

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Retraction Open Access

[Retracted] microRNA‑206 overexpression inhibits cellular proliferation and invasion of estrogen receptor α‑positive ovarian cancer cells

Shaoru Li, Yan Li, Zhengfang Wen, Fanjing Kong, Xinlei Guan, Wenhui Liu
Article Number: 640
Published online on: 09 July 2021

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Retraction Open Access

[Retracted] microRNA‑335 inhibits proliferation, cell‑cycle progression, colony formation, and invasion via targeting PAX6 in breast cancer cells

Yuanbiao Meng, Quanqing Zou, Tianqi Liu, Xiaoyong Cai, Yubin Huang, Jinfei Pan
Article Number: 639
Published online on: 09 July 2021

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Article Open Access

Cinnamaldehyde inhibits psoriasis‑like inflammation by suppressing proliferation and inflammatory response of keratinocytes via inhibition of NF‑κB and JNK signaling pathways

Zhenzhen Ding, Jingjing Liu, Huangjing Qian, Lingjian Wu, Mingfen Lv
Article Number: 638
Published online on: 07 July 2021

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Article Open Access

Hypoxia‑induced lactate dehydrogenase A protects cells from apoptosis in endometriosis

Jinyan Zheng, Yongdong Dai, Xiang Lin, Qianmeng Huang, Libing Shi, Xiaoying Jin, Na Liu, Feng Zhou, Songying Zhang
Article Number: 637
Published online on: 06 July 2021

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Article Open Access

Interactions between the ERK1/2 signaling pathway and PCAF play a key role in PE‑induced cardiomyocyte hypertrophy

Qian Mao, Shuqi Wu, Chang Peng, Bohui Peng, Xiaomei Luo, Lixin Huang, Huanting Zhang
Article Number: 636
Published online on: 06 July 2021

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Article Open Access

Chemokine CCL20 promotes the paclitaxel resistance of CD44+CD117+ cells via the Notch1 signaling pathway in ovarian cancer

Min Chen, Juan Su, Chunmei Feng, Ying Liu, Li Zhao, Yongjie Tian
Article Number: 635
Published online on: 06 July 2021

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Article Open Access

Sirt3 promotes the autophagy of HK‑2 human proximal tubular epithelial cells via the inhibition of Notch‑1/Hes‑1 signaling

Ying Wang, Jiang Chang, Zi-Qiang Wang, Ying Li
Article Number: 634
Published online on: 06 July 2021

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Article Open Access

miR‑3613‑3p/MAP3K2/p38/caspase‑3 pathway regulates the heat‑stress‑induced apoptosis of endothelial cells

Jie Liu, Siya Xu, Shixin Liu, Bingguan Chen
Article Number: 633
Published online on: 06 July 2021

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Article Open Access

ZIC2 upregulates lncRNA SNHG12 expression to promote endometrial cancer cell proliferation and migration by activating the Notch signaling pathway

Pengyu Cai, Gaijuan Li, Mingxiu Wu, Bin Zhang, Hong Bai
Article Number: 632
Published online on: 05 July 2021

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Article Open Access

Whole‑genome identification and systematic analysis of lncRNA‑mRNA co‑expression profiles in patients with cutaneous basal cell carcinoma

Jiaan Zhang, Xuyue Zhou, Chenpu Zhu, Yu Hu, Rong Li, Shuang Jin, Dan Huang, Mei Ju, Kun Chen, Chao Luan
Article Number: 631
Published online on: 05 July 2021

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Review

Chloride intracellular channels as novel biomarkers for digestive system tumors (Review)

Hui Wang, Jiaxing An, Suyu He, Chengcheng Liao, Juan Wang, Biguang Tuo
Article Number: 630
Published online on: 05 July 2021

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Article Open Access

Oxaliplatin promotes siMAD2L2‑induced apoptosis in colon cancer cells

Lu Ma, Xin Li, Xiaopeng Zhao, Haotong Sun, Feifei Kong, Yuanjie Li, Yu Sui, Fang Xu
Article Number: 629
Published online on: 05 July 2021

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Correction Open Access

[Corrigendum] Lentivirus‑mediated RNA interference of clusterin enhances the chemosensitivity of EJ bladder cancer cells to epirubicin in vitro

Jian Lu, Jun-Hang Luo, Jian Pang, Jia-Zheng Cao, Rong-Hai Wu, Zhu-Ting Tong, Wei Chen, Dan Xie
Article Number: 628
Published online on: 01 July 2021

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Article Open Access

MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch

Yushi Cao, Zhongwen Cao, Weitie Wang, Xiangyu Jie, Lei Li
Article Number: 627
Published online on: 01 July 2021

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Correction Open Access

[Erratum] Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells (Review)

Ying Li, Jinming Wang, Weiliang Zhong
Article Number: 626
Published online on: 30 June 2021

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Article Open Access

Differences in TNF‑α and TNF‑R1 expression in damaged neurons and activated astrocytes of the hippocampal CA1 region between young and adult gerbils following transient forebrain ischemia

Choong Hyun Lee, Ji Hyeon Ahn, Bai Hui Chen, Dae Won Kim, Hyejin Sim, Tae-Kyeong Lee, Joon Ha Park, Moo-Ho Won, Soo Young Choi
Article Number: 625
Published online on: 30 June 2021

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Article Open Access

Effect of Tongfu Xingshen capsule on the endogenous neural stem cells of experimental rats with intracerebral hemorrhage

Zhizhong Cui, Shanshan Liu, Lingbo Hou, Yifan Sun, Haoxuan Chen, Hui Mao, Yuanqi Zhao, Lijun Qiao
Article Number: 624
Published online on: 30 June 2021

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Article Open Access

Inhibitory effect of gefitinib derivative LPY‑9 on human glioma

Yuchen Sun, Liangzhao Chu, Huijuan Wang, Han Peng, Jian Liu
Article Number: 623
Published online on: 30 June 2021

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Article Open Access

Interference with KCNJ2 inhibits proliferation, migration and EMT progression of apillary thyroid carcinoma cells by upregulating GNG2 expression

Siyuan Chen, Miaoming Huang, Xiarong Hu
Article Number: 622
Published online on: 30 June 2021

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Article Open Access

Protective effects of the knockdown of lncRNA AK139328 against oxygen glucose deprivation/reoxygenation-induced injury in PC12 cells

Liyan Liu, Bin Zheng, Zhaoxia Wang
Article Number: 621
Published online on: 30 June 2021

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Correction Open Access

[Corrigendum] 20(s)‑ginseonside‑Rg3 modulation of AMPK/FoxO3 signaling to attenuate mitochondrial dysfunction in a dexamethasone‑injured C2C12 myotube‑based model of skeletal atrophy in vitro

Manying Wang, Rui Jiang, Jianzeng Liu, Xiaohao Xu, Guang Sun, Daqing Zhao, Liwei Sun
Article Number: 620
Published online on: 30 June 2021

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Long non‑coding RNA HOTTIP enhances the fibrosis of lung tissues by regulating the miR‑744‑5p/PTBP1 signaling axis

Jing Li, Wenshu Chai, Zhuo Zhao, Yan Zhou, Qi Wu
Article Number: 619
Published online on: 30 June 2021

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October-2026 Volume 34 Issue 4

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Licoisoflavone A ameliorates adipose tissue dysfunction in diet‑induced obesity by promoting METTL3 expression

Shuangxi Tu, Xiaodan Wang, Zhenbo Wang, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 296
Published online on: 03 September 2026

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Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review)

Amahle Nyalambisa, Afra Basera, Ntombikayise Xelwa, Olalekan Fadebi, Zodwa Dlamini, Rahaba Marima
Article Number: 295
Published online on: 03 September 2026

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From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review)

Yuying Li, Ling Wei, Fang Sun, Huixia Wu, Xijun Sun, Yirong Gan, Xiaohua Kong
Article Number: 294
Published online on: 03 September 2026

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Resurrection biology: Melatonin as a modulator of anastasis (Review)

Alexandros Georgiou, Russel J. Reiter, Vassilis Zoumpourlis, Demetrios A. Spandidos
Article Number: 293
Published online on: 02 September 2026

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[Corrigendum] CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Article Number: 292
Published online on: 01 September 2026

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Natural medicine‑empowered treatment of depression via restoring neurogenesis (Review)

Xiufen Zhong, Jingtao Gui
Article Number: 291
Published online on: 28 August 2026

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POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy

Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Article Number: 290
Published online on: 26 August 2026

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[Corrigendum] Human cytomegalovirus RL13 protein interacts with host NUDT14 protein affecting viral DNA replication

Guili Wang, Gaowei Ren, Xin Cui, Zhitao Lu, Yanping Ma, Ying Qi, Yujing Huang, Zhongyang Liu, Zhengrong Sun, Qiang Ruan
Article Number: 289
Published online on: 24 August 2026

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Autophagy: Mechanisms and therapeutic perspectives in intestinal metaplasia (Review)

Laifeng Wu, Lingchen Liao, Ziwei Xia, Qiao Zeng, An Huang, Zhiyong Cao
Article Number: 288
Published online on: 21 August 2026

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Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review)

Xi Wang, Baojun Duan, Jun Bai, Huitong Liu
Article Number: 287
Published online on: 20 August 2026

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Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review)

Jianhui Li, Annan Liu, Wei Gao, Liping Xing, Peihan Duan, Honglin Li
Article Number: 286
Published online on: 20 August 2026

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Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis

Junjian Chen, Wanyi Zhang, Tao Hong, Junsheng Wang, Chuan Chen, Ying Zhang, Mi Hu, Ning You, Jietao Huang
Article Number: 285
Published online on: 20 August 2026

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[Corrigendum] Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons 

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Article Number: 284
Published online on: 20 August 2026

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Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review)

Qianqian Li, Yufang Ni, Zhaoyang Li, Jianchun Li, Li Wang
Article Number: 283
Published online on: 18 August 2026

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Biological mechanisms of atropine in myopia control (Review)

Qin Zhu, Guanglong Zhou, Lingguo Wang, Xuejiao Li, Zhijuan Hua, Jie Yin, Jieying Zhang, Yuan Zhou, Xiaofan Zhang, Allison Wilde, Yingting Zhu, Liping Xue
Article Number: 282
Published online on: 18 August 2026

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6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota

Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, Fei Li, Baochun Shen
Article Number: 281
Published online on: 18 August 2026

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[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival  

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma
Article Number: 280
Published online on: 17 August 2026

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Uric acid enhances tumor stemness in breast cancer cells by upregulating GMPS

Zhiying Wang, Mingzhang Huang, Yuanqi Zhang, Siqi Huang, Wei Lei, Xiaorong Shui
Article Number: 279
Published online on: 13 August 2026

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Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis

Le-Yi Huang, Yao Chen, Lin-Ran Song, Zhuo-Lin Zhong, Kamran Ali, Hui-Min Li, Qing-Feng Hu, Hong-Hua Hu
Article Number: 278
Published online on: 13 August 2026

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[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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