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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2015 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

CLC-3 channels in cancer (Review)

Sen Hong, Miaomiao Bi, Lei Wang, Zhenhua Kang, Limian Ling, Chunyan Zhao
Pages: 507-514
Published online on: 21 November 2014

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Review

Epithelial-mesenchymal transition‑associated microRNAs in colorectal cancer and drug-targeted therapies (Review)

Danjuan Jin, Yantian Fang, Zhengyang Li, Zongyou Chen, Jianbin Xiang
Pages: 515-525
Published online on: 01 December 2014

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Article Open Access

Ad-p53 enhances the sensitivity of triple-negative breast cancer MDA-MB-468 cells to the EGFR inhibitor gefitinib

Xinzhao Wang, Hongkuan Song, Qian Yu, Qi Liu, Leilei Wang, Zhaoyun Liu, Zhiyong Yu
Pages: 526-532
Published online on: 11 December 2014

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Article Open Access

BKCa channel inhibitor modulates the tumorigenic ability of hormone-independent breast cancer cells via the Wnt pathway

Brandon M. Schickling, Sarah K. England, Nukhet Aykin-Burns, Lyse A. Norian, Kimberly K. Leslie, Victoria P. Frieden-Korovkina
Pages: 533-538
Published online on: 24 November 2014

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Article Open Access

Galanin plays an important role in cancer invasiveness and is associated with poor prognosis in stage II colorectal cancer

Kinuko Nagayoshi, Takashi Ueki, Kosuke Tashiro, Yusuke Mizuuchi, Tatsuya Manabe, Hiromitsu Araki, Yoshinao Oda, Satoru Kuhara, Masao Tanaka
Pages: 539-546
Published online on: 09 December 2014

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Article Open Access

Identification of a novel EXT1 mutation in patients with hereditary multiple exostosis by exome sequencing

Hongjie Liu, Song Wu, Li Duan, Weiming Zhu, Shiquan Zhang, Xiaoxiao Hu, Wenlong Jia, Guosheng Yang, Chunxiao Liu, Weiping Li, Lei Yang, Lijun Guo, Youcheng Lin, Yongqiang Wang, Meijian He, Zhao Yang, Yingying He, Zhiming Cai, Daping Wang
Pages: 547-552
Published online on: 21 November 2014

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Article Open Access

Protein-bound polysaccharide K suppresses tumor fibrosis in gastric cancer by inhibiting the TGF-β signaling pathway

Toshifumi Shinbo, Sachio Fushida, Tomoya Tsukada, Shinichi Harada, Jun Kinoshita, Katsunobu Oyama, Koichi Okamoto, Itasu Ninomiya, Hiroyuki Takamura, Hirohisa Kitagawa, Takeshi Fujimura, Masakazu Yashiro, Kousei Hirakawa, Tetsuo Ohta
Pages: 553-558
Published online on: 28 November 2014

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Article Open Access

Transcriptional silencing of ETS-1 abrogates epithelial-mesenchymal transition resulting in reduced motility of pancreatic cancer cells

Chunyan Li, Zhonghan Wang, Yan Chen, Min Zhou, Haijun Zhang, Rong Chen, Fangfang Shi, Cailian Wang, Zongdao Rui
Pages: 559-565
Published online on: 21 November 2014

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Article

Synergistic induction of apoptosis by mapatumumab and anthracyclines in human bladder cancer cells

Syed Minhaj Uddin Ahmed, Xiuxian Wu, Xinghua Jin, Xia Zhang, Yoshikazu Togo, Toru Suzuki, Yongnan Li, Akihiro Kanematsu, Mikio Nojima, Shingo Yamamoto, Mikio Sugimoto, Yoshiyuki Kakehi
Pages: 566-572
Published online on: 05 December 2014

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Article

Clinical significance of microRNA-21 as a biomarker in each Dukes' stage of colorectal cancer

Yoshihisa Fukushima, Hisae Iinuma, Mitsuo Tsukamoto, Keiji Matsuda, Yojiro Hashiguchi
Pages: 573-582
Published online on: 21 November 2014

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Article

5-Aminolevulinic acid strongly enhances delayed intracellular production of reactive oxygen species (ROS) generated by ionizing irradiation: Quantitative analyses and visualization of intracellular ROS production in glioma cells in vitro

Takehiro Kitagawa, Junkoh Yamamoto, Tohru Tanaka, Yoshiteru Nakano, Daisuke Akiba, Kunihiro Ueta, Shigeru Nishizawa
Pages: 583-590
Published online on: 24 November 2014

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Article

Expression of miR-136 is associated with the primary cisplatin resistance of human epithelial ovarian cancer

Henan Zhao, Sha Liu, Guang Wang, Xian Wu, Yanfang Ding, Gordon Guo, Jiyong Jiang, Shiying Cui
Pages: 591-598
Published online on: 02 December 2014

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Article

Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas

Anna A. Brożyna, Wojciech Jóźwicki, Cezary Jochymski, Andrzej T. Slominski
Pages: 599-606
Published online on: 11 December 2014

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Article

miR-203 enhances chemosensitivity to 5-fluorouracil by targeting thymidylate synthase in colorectal cancer

Tao Li, Feng Gao, Xi-Peng Zhang
Pages: 607-614
Published online on: 04 December 2014

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Article

Overexpression of CX3CR1 is associated with cellular metastasis, proliferation and survival in gastric cancer

Lu-Min Wei, Shan Cao, Wei-Dong Yu, Yu-Lan Liu, Jing-Tong Wang
Pages: 615-624
Published online on: 04 December 2014

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Case Report

MLLT10 and IL3 rearrangement together with a complex four-way translocation and trisomy 4 in a patient with early T-cell precursor acute lymphoblastic leukemia: A case report

Moneeb A.K. Othman, Joana B. Melo, Isabel M. Carreira, Martina Rincic, Eyad Alhourani, Kathleen Wilhelm, Bernd Gruhn, Anita Glaser, Thomas Liehr
Pages: 625-630
Published online on: 25 November 2014

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Article

Apoptotic effects of 7,8-dihydroxyflavone in human oral squamous cancer cells through suppression of Sp1

Ra Ham Lee, Jae-Cheon Shin, Ka-Hwi Kim, Yung Hyun Choi, Jung-Il Chae, Jung-Hyun Shim
Pages: 631-638
Published online on: 27 November 2014

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Article

The indicative function of Twist2 and E-cadherin in HPV oncogene-induced epithelial-mesenchymal transition of cervical cancer cells

Yuan Liu, Wenyan Qian, Jiawen Zhang, Yu Dong, Can Shi, Zhiqiang Liu, Sufang Wu
Pages: 639-650
Published online on: 24 November 2014

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Article

Downregulation of MACC1 inhibits invasion, migration and proliferation, attenuates cisplatin resistance and induces apoptosis in tongue squamous cell carcinoma

Hai-Feng Li, Ye-Qing Liu, Zhuo-Jian Shen, Xiang-Feng Gan, Jing‑Jing Han, Yun-Yun Liu, Hai-Gang Li, Zhi-Quan Huang
Pages: 651-660
Published online on: 21 November 2014

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Article

Inhibition of 5-lipoxygenase triggers apoptosis in pancreatic cancer cells Retraction in /10.3892/or.2024.8853

Guo-Xiong Zhou, Xiao-Ling Ding, Sheng-Bao Wu, Hai-Feng Zhang, Wei Cao, Li-Shuai Qu, Hong Zhang
Pages: 661-668
Published online on: 05 December 2014

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Article

Kisspeptin-10 inhibits the migration of breast cancer cells by regulating epithelial-mesenchymal transition

Guo-Qing Song, Yi Zhao
Pages: 669-674
Published online on: 24 November 2014

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Article

T7 peptide inhibits angiogenesis via downregulation of angiopoietin-2 and autophagy Corrigendum in /10.3892/or.2024.8779

Fuhai Wang, Xiaofeng Dong, Peng Xiu, Jingtao Zhong, Honglong Wei, Zongzhen Xu, Tao Li, Feng Liu, Xueying Sun, Jie Li
Pages: 675-684
Published online on: 05 December 2014

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Article

Expression of hMOF in different ovarian tissues and its effects on ovarian cancer prognosis

Mingbo Cai, Zhenhua Hu, Juanjuan Liu, Jian Gao, Mingzi Tan, Danye Zhang, Liancheng Zhu, Shuice Liu, Rui Hou, Bei Lin
Pages: 685-692
Published online on: 05 December 2014

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Article

Diosgenin induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma cells

Yongjian Li, Xiaorong Wang, Silu Cheng, Juan Du, Zhengting Deng, Yani Zhang, Qun Liu, Jingdong Gao, Binbin Cheng, Changquan Ling
Pages: 693-698
Published online on: 26 November 2014

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Article

Anti-angiogenic effects of Siegesbeckia glabrescens are mediated by suppression of the Akt and p70S6K-dependent signaling pathways

Hyeon-Ju Kim, Hee-Young Ko, Shin-Wook Choi, Dong-Wan Seo
Pages: 699-704
Published online on: 26 November 2014

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Article

Upregulation of the miR-212/132 cluster suppresses proliferation of human lung cancer cells

Xin Jiang, Xialin Chen, Ling Chen, Yan Ma, Linyan Zhou, Qiufeng Qi, Yongping Liu, Shuyu Zhang, Judong Luo, Xifa Zhou
Pages: 705-712
Published online on: 01 December 2014

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Article

miR-200a suppresses cell growth and migration by targeting MACC1 and predicts prognosis in hepatocellular carcinoma

Jiye Feng, Jinbo Wang, Mingliang Chen, Gun Chen, Zongyang Wu, Liping Ying, Qifeng Zhuo, Jianlei Zhang, Weilin Wang
Pages: 713-720
Published online on: 02 December 2014

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Article

Nicotinamide sensitizes human breast cancer cells to the cytotoxic effects of radiation and cisplatin

G. Domínguez-Gómez, J. Díaz-Chávez, A. Chávez-Blanco, A. Gonzalez-Fierro, J. E. Jiménez-Salazar, P. Damián-Matsumura, L. E. Gómez-Quiroz, A. Dueñas-González
Pages: 721-728
Published online on: 09 December 2014

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Article

Inhibitory effects of the recombinant human serine protease inhibitor Hespintor on the proliferation, migration and invasion of hepatocellular carcinoma cells

Xue-Lei Wang, Yue Li, Xiao-Yan Cheng, Qing Chi, Xiao-Kun Yao, Hui-Juan Wu, Yong-Zhi Lun
Pages: 729-736
Published online on: 12 December 2014

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Article

Baicalein inhibits the invasion of gastric cancer cells by suppressing the activity of the p38 signaling pathway

Xi Yan, Xiaojiang Rui, Kai Zhang
Pages: 737-743
Published online on: 11 December 2014

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Article

Metformin potentiates the anticancer effects of cisplatin under normoxic conditions in vitro

Takashi Uehara, Akira Mitsuhashi, Nobuhide Tsuruoka, Makio Shozu
Pages: 744-750
Published online on: 21 November 2014

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Article

G31P, CXCR1/2 inhibitor, with cisplatin inhibits the growth of mice hepatocellular carcinoma and mitigates high‑dose cisplatin-induced nephrotoxicity

Lingyun Li, Muhammad Noman Khan, Qiang Li, Xiangyu Chen, Jing Wei, Bing Wang, Jya-Wei Cheng, John R. Gordon, Fang Li
Pages: 751-757
Published online on: 08 December 2014

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Article

Effects of ephrinB2 gene siRNA on the biological behavior of human colorectal cancer cells

Peiwu Li, Wangsheng Chen, Yingzhen Wang, Xu Fu, Kunming Wen, Jiang Qian, Chun Huang, Zhongxue Fu
Pages: 758-766
Published online on: 27 November 2014

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Article

High expression of Janus kinase 2 in background normal liver tissue of resected hepatocellular carcinoma is associated with worse prognosis

Fuminori Sonohara, Shuji Nomoto, Yoshikuni Inokawa, Mitsuhiro Hishida, Nao Takano, Mitsuro Kanda, Yoko Nishikawa, Tsutomu Fujii, Masahiko Koike, Hiroyuki Sugimoto, Yasuhiro Kodera
Pages: 767-773
Published online on: 25 November 2014

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Article

Synergistic effects of eukaryotic co-expression plasmid-based STAT3-specific siRNA and LKB1 on ovarian cancer in vitro and in vivo Retraction in /10.3892/or.2021.8149

Yuan Pan, Liqun Zhang, Xinyue Zhang, Ruizhi Liu
Pages: 774-782
Published online on: 25 November 2014

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Article

Efficacy of dual-functional liposomes containing paclitaxel for treatment of lung cancer Retraction in /10.3892/or.2017.6006

Rong-Hua Wang, Hong-Mei Cao, Zhi-Ju Tian, Bo Jin, Qing Wang, Hong Ma, Jing Wu
Pages: 783-791
Published online on: 02 December 2014

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Article

HBx protein-induced upregulation of microRNA-221 promotes aberrant proliferation in HBV‑related hepatocellular carcinoma by targeting estrogen receptor-α

Juan-Juan Chen, Yi-Shu Tang, Shi-Feng Huang, Jian-Gang Ai, Hai-Xia Wang, Li-Ping Zhang
Pages: 792-798
Published online on: 04 December 2014

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Article

MPA influences tumor cell proliferation, migration, and invasion induced by RANKL through PRB involving the MAPK pathway in endometrial cancer

Jing Wang, Xiao Sun, Huijuan Zhang, Yudong Wang, Yuhong Li
Pages: 799-809
Published online on: 05 December 2014

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Article

Targeting antitumor effect of rhTNF-α fusion protein mediated by matrix metalloproteinase-2

Xin Shao, Hui Ren, Yue-Li Wang, Fa Wang, Gan Hou, Di-Nan Huang
Pages: 810-818
Published online on: 24 November 2014

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Article

Upregulated circulating miR-150 is associated with the risk of intrahepatic cholangiocarcinoma

Shouli Wang, Jikai Yin, Tao Li, Lijuan Yuan, Dong Wang, Jiaxing He, Xilin Du, Jianguo Lu
Pages: 819-825
Published online on: 02 December 2014

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Article

Combination therapy with α-galactosylceramide and a Toll-like receptor agonist exerts an augmented suppressive effect on lung tumor metastasis in a mouse model

Tatsuya Ando, Hiroyasu Ito, Yuko Arioka, Hideyuki Ogiso, Mitsuru Seishima
Pages: 826-832
Published online on: 28 November 2014

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Article

Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer

Ningning Cheng, Xuefei Li, Chao Zhao, Shengxiang Ren, Xiaoxia Chen, Weijing Cai, Mingchuan Zhao, Yishi Zhang, Jiayu Li, Qi Wang, Caicun Zhou
Pages: 833-839
Published online on: 02 December 2014

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Article

Isoquercitrin inhibits the progression of pancreatic cancer in vivo and in vitro by regulating opioid receptors and the mitogen-activated protein kinase signalling pathway Retraction in /10.3892/or.2023.8505

Quan Chen, Ping Li, Ping Li, Yong Xu, Yang Li, Bo Tang
Pages: 840-848
Published online on: 26 November 2014

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Article

Chemokine receptor 7 promotes tumor migration and invasiveness via the RhoA/ROCK pathway in metastatic squamous cell carcinoma of the head and neck

Zhongfei Xu, Xiaojiao Zheng, Liangliang Yang, Fayu Liu, Enjiao Zhang, Weiyi Duan, Shuang Bai, Jawad Safdar, Zhenning Li, Changfu Sun
Pages: 849-855
Published online on: 27 November 2014

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Article

Patrinia scabiosaefolia inhibits the proliferation of colorectal cancer in vitro and in vivo via G1/S cell cycle arrest

Mingyue Zhang, Guodong Sun, Aling Shen, Liya Liu, Jingzhen Ding, Jun Peng
Pages: 856-860
Published online on: 10 December 2014

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Article

Ampelopsin reduces the migration and invasion of ovarian cancer cells via inhibition of epithelial-to-mesenchymal transition

Tianfeng Liu, Peishu Liu, Feng Ding, Nina Yu, Shihong Li, Surong Wang, Xiaofei Zhang, Xiangxiu Sun, Ying Chen, Feng Wang, Yunhe Zhao, Bo Li
Pages: 861-867
Published online on: 12 December 2014

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Article

Kaempferol inhibits gastric cancer tumor growth: An in vitro and in vivo study

Haibin Song, Junjie Bao, Yuzhe Wei, Yang Chen, Xiaoguang Mao, Jianguo Li, Zhiwei Yang, Yingwei Xue
Pages: 868-874
Published online on: 09 December 2014

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Article

Lactate promotes resistance to glucose starvation via upregulation of Bcl-2 mediated by mTOR activation

Chen Huang, Shile Sheng, Rui Li, Xiaoguang Sun, Jianju Liu, Gang Huang
Pages: 875-884
Published online on: 08 December 2014

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Article

MTA1 downregulation inhibits malignant potential in a small cell lung cancer cell line

Hongsheng Xue, Haijuan Wang, Jian Liu, Huan Liu, Chunxiao Li, Li Han, Chen Lin, Qimin Zhan, Zhilong Zhao, Haili Qian
Pages: 885-892
Published online on: 12 December 2014

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Article

Effect of LIV1 on the sensitivity of ovarian cancer cells to trichostatin A

Xiaoli Ma, Hua Duan, Jia Liu, Qingqing Mo, Chengjuan Sun, Ding Ma, Jiandong Wang
Pages: 893-898
Published online on: 25 November 2014

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Article

Inhibition of PGC-1α after chemotherapy-mediated insult confines multiple myeloma cell survival by affecting ROS accumulation

Dedong Cao, Lu Jin, Hao Zhou, Wen Yu, Yu Hu, Tao Guo
Pages: 899-904
Published online on: 28 November 2014

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Article

Omi/HtrA2 pro-apoptotic marker differs in various hepatocellular carcinoma cell lines owing to ped/pea-15 expression level Corrigendum in /10.3892/or.2024.8804

Zongquan Xu, Yu Chen, Guohui Xu, Cheng Peng, Enyu Liu, Yunguang Li, Jun Niu, Changhai Li
Pages: 905-912
Published online on: 08 December 2014

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Article

Glucose-dependent glucose transporter 1 expression and its impact on viability of thyroid cancer cells

Paweł Jóźwiak, Anna Krześlak, Magdalena Bryś, Anna Lipińska
Pages: 913-920
Published online on: 12 December 2014

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Article

17β-estradiol-containing liposomes as a novel delivery system for the antisense therapy of ER-positive breast cancer: An in vitro study on the MCF-7 cell line

Zbynek Heger, Jaromir Gumulec, Natalia Cernei, Katerina Tmejova, Pavel Kopel, Jan Balvan, Michal Masarik, Ondrej Zitka, Miroslava Beklova, Vojtech Adam, Rene Kizek
Pages: 921-929
Published online on: 26 November 2014

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Article

Sister chromatid exchange: A possible approach to characterize familial breast cancer patients

Ivana De Pascalis, Brunella Pilato, Annalisa Mazzotta, Teresa Stefania Dell'Endice, Vincenza Rubini, Giovanni Simone, Angelo Paradiso, Vincenzo Aiello, Anita Mangia
Pages: 930-934
Published online on: 26 November 2014

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Article

Case-control study of the PERIOD3 clock gene length polymorphism and colorectal adenoma formation

Melannie Alexander, James B. Burch, Susan E. Steck, Chin‑Fu Chen, Thomas G. Hurley, Philip Cavicchia, Meredith Ray, Nitin Shivappa, Jaclyn Guess, Hongmei Zhang, Shawn D. Youngstedt, Kim E. Creek, Stephen Lloyd, Xiaoming Yang, James R. Hébert
Pages: 935-941
Published online on: 11 December 2014

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Article

miR-23a promotes cisplatin chemoresistance and protects against cisplatin-induced apoptosis in tongue squamous cell carcinoma cells through Twist

Fusen Peng, Hailin Zhang, Youhong Du, Pingqing Tan
Pages: 942-950
Published online on: 10 December 2014

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Biomarkers for predicting response to tyrosine kinase inhibitors in drug-sensitive and drug-resistant human bladder cancer cells

Jixia Li, Bihua Lin, Xiangyong Li, Xudong Tang, Zhiwei He, Keyuan Zhou
Pages: 951-957
Published online on: 02 December 2014

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Article

The V-val subtype Epstein-Barr virus nuclear antigen 1 promotes cell survival after serum withdrawal

Mei Chao, Hsiao-Ning Wang, Yi Jin Lu, Yu-Sun Chang, Jau-Song Yu
Pages: 958-966
Published online on: 25 November 2014

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Article

Thioredoxin-1 inhibitor, 1-methylpropyl 2-imidazolyl disulfide, inhibits the growth, migration and invasion of colorectal cancer cell lines

Fule Wang, Feiyan Lin, Peili Zhang, Wuhua Ni, Laixi Bi, Jianbo Wu, Lei Jiang
Pages: 967-973
Published online on: 05 December 2014

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Article

miR-26b is downregulated in human tongue squamous cell carcinoma and regulates cell proliferation and metastasis through a COX-2-dependent mechanism

Jing Cao, Tao Guo, Qingshan Dong, Jianqiang Zhang, Yanfeng Li
Pages: 974-980
Published online on: 05 December 2014

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Article

miR-218 suppresses tumor growth and enhances the chemosensitivity of esophageal squamous cell carcinoma to cisplatin Retraction in /10.3892/or.2022.8265

Hang Tian, Lei Hou, Yu-Mei Xiong, Jun-Xiang Huang, Ying-Jun She, Xiao-Bao Bi, Xing-Rong Song
Pages: 981-989
Published online on: 08 December 2014

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Article

HOXA7 stimulates human hepatocellular carcinoma proliferation through cyclin E1/CDK2

Yuehui Li, Xiao Hui Yang, Shu Juang Fang, Chang Fei Qin, Rui Li Sun, Zhao Yang Liu, Bin Yuan Jiang, Xiang Wu, Guancheng Li
Pages: 990-996
Published online on: 11 December 2014

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Article

Overexpression of Lin28 inhibits the proliferation, migration and cell cycle progression and induces apoptosis of BGC-823 gastric cancer cells

Hu Song, Wei Xu, Jun Song, Yong Liang, Wei Fu, Xiao‑Cheng Zhu, Chao Li, Jun-Sheng Peng, Jun-Nian Zheng
Pages: 997-1003
Published online on: 15 December 2014

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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