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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2016 Volume 14 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Neurogenesis-based epigenetic therapeutics for Alzheimer's disease (Review)

Xueyuan Li, Xinjie Bao, Renzhi Wang
Pages: 1043-1053
Published online on: 10 June 2016

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Article Open Access

Effect of glucocorticoids on osteoclast function in a mouse model of bone necrosis

Ming He, Jiashi Wang, Guangbin Wang, Ye Tian, Linlin Jiang, Zhaozhou Ren, Chuang Qiu, Qin Fu
Pages: 1054-1060
Published online on: 06 June 2016

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Article Open Access

N-ethylmaleimide‑sensitive factor siRNA inhibits the release of Weibel-Palade bodies in endothelial cells

Yong Zhou, Shui‑Xiang Yang, Yu‑Nan Yue, Xiao‑Fei Wei, Yan Liu
Pages: 1061-1066
Published online on: 07 June 2016

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Article Open Access

Effects of 17-AAG on the cell cycle and apoptosis of H446 cells and the associated mechanisms

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Pages: 1067-1074
Published online on: 06 June 2016

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Article Open Access

Overexpression of neuromedin U is correlated with regional metastasis of head and neck squamous cell carcinoma

Lei Wang, Chen Chen, Fen Li, Qing‑Quan Hua, Shiming Chen, Bokui Xiao, Mengyuan Dai, Man Li, Anyuan Zheng, Di Yu, Zhang Wei Hu, Zezhang Tao
Pages: 1075-1082
Published online on: 27 May 2016

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Article Open Access

Roscovitine ameliorates endotoxin-induced uveitis through neutrophil apoptosis

Zhao‑Xin Jiang, Suo Qiu, Bing‑Sheng Lou, Yao Yang, Wen‑Cong Wang, Xiao‑Feng Lin
Pages: 1083-1090
Published online on: 03 June 2016

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Article Open Access

Mangiferin inhibits macrophage classical activation via downregulating interferon regulatory factor 5 expression

Zhiquan Wei, Li Yan, Yixin Chen, Chuanhong Bao, Jing Deng, Jiagang Deng
Pages: 1091-1098
Published online on: 27 May 2016

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Article Open Access

Immunolocalization of MMP9 and MMP2 in osteolytic metastasis originating from MDA-MB-231 human breast cancer cells

Bo Liu, Jian Cui, Jing Sun, Juan Li, Xiuchun Han, Jie Guo, Min Yi, Norio Amizuka, Xin Xu, Minqi Li
Pages: 1099-1106
Published online on: 07 June 2016

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Article Open Access

CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade

Zong‑Sheng Tang, You‑Hua Hao, E‑Juan Zhang, Chun‑Li Xu, Yun Zhou, Xin Zheng, Dong‑Liang Yang
Pages: 1107-1116
Published online on: 13 June 2016

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Article Open Access

Flowers of Camellia nitidissima cause growth inhibition, cell-cycle dysregulation and apoptosis in a human esophageal squamous cell carcinoma cell line

Lu Dai, Ji‑Lin Li, Xin‑Qiang Liang, Lin Li, Yan Feng, Hai‑Zhou Liu, Wen‑Er Wei, Shu‑Fang Ning, Li‑Tu Zhang
Pages: 1117-1122
Published online on: 10 June 2016

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Article Open Access

Paeoniflorin ameliorates acute necrotizing pancreatitis and pancreatitis‑induced acute renal injury

Peng Wang, Weixing Wang, Qiao Shi, Liang Zhao, Fangchao Mei, Chen Li, Teng Zuo, Xiaobo He
Pages: 1123-1131
Published online on: 27 May 2016

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Article Open Access

Molecular docking studies of Traditional Chinese Medicinal compounds against known protein targets to treat non-small cell lung carcinomas

Guo-Fang Zhao, Zuo-An Huang, Xue-Kui Du, Ming-Lei Yang, Dan-Dan Huang, Shun Zhang
Pages: 1132-1138
Published online on: 27 May 2016

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Article Open Access

Histone acetylation is involved in TCDD‑induced cleft palate formation in fetal mice

Xingang Yuan, Lin Qiu, Yalan Pu, Cuiping Liu, Xuan Zhang, Chen Wang, Wei Pu, Yuexian Fu
Pages: 1139-1145
Published online on: 27 May 2016

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Article Open Access

Ag85A/ESAT-6 chimeric DNA vaccine induces an adverse response in tuberculosis-infected mice

Yan Liang, Xuejuang Bai, Junxian Zhang, Jingying Song, Yourong Yang, Qi Yu, Ning Li, Xueqiong Wu
Pages: 1146-1152
Published online on: 03 June 2016

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Article Open Access

Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance

Lei Gu, Wen‑Sheng Deng, Xiao‑Fei Sun, Hong Zhou, Qing Xu
Pages: 1153-1161
Published online on: 10 June 2016

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Article Open Access

Genomic expression profiling and bioinformatics analysis on diabetic nephrology with ginsenoside Rg3

Juan Wang, Chunli Cui, Li Fu, Zili Xiao, Nanzi Xie, Yang Liu, Lu Yu, Haifeng Wang, Bangzhen Luo
Pages: 1162-1172
Published online on: 27 May 2016

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Article Open Access

Modified Pulsatilla decoction attenuates oxazolone-induced colitis in mice through suppression of inflammation and epithelial barrier disruption

Xuewei Wang, Fugang Fan, Qin Cao
Pages: 1173-1179
Published online on: 02 June 2016

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Article Open Access

Expression of miR-199a-3p in human adipocytes is regulated by free fatty acids and adipokines

Nan Gu, Lianghui You, Chunmei Shi, Lei Yang, Lingxia Pang, Xianwei Cui, Chenbo Ji, Wen Zheng, Xirong Guo
Pages: 1180-1186
Published online on: 08 June 2016

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Article Open Access

Induction of adipose-derived stem cells into Schwann-like cells and observation of Schwann-like cell proliferation

Xiumei Fu, Zhaoxue Tong, Qi Li, Qingfei Niu, Zhe Zhang, Xiaojie Tong, Lei Tong, Xu Zhang
Pages: 1187-1193
Published online on: 06 June 2016

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Article Open Access

Isolation, culture, purification and ultrastructural investigation of cardiac telocytes

Yan‑Yan Li, Song Zhang, Yi‑Gang Li, Yan Wang
Pages: 1194-1200
Published online on: 10 June 2016

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Article Open Access

Abnormal osteogenic and chondrogenic differentiation of human mesenchymal stem cells from patients with adolescent idiopathic scoliosis in response to melatonin

Chong Chen, Caixia Xu, Taifeng Zhou, Bo Gao, Hang Zhou, Changhua Chen, Changli Zhang, Dongsheng Huang, Peiqiang Su
Pages: 1201-1209
Published online on: 10 June 2016

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Article

Autophagic death induced by thermo‑chemotherapy in gastric cancer cells results from the reactive oxygen species pathway

Yinbing Wu, Mingxin Pan, Shuzhong Cui, Mingchen Ba, Zulong Chen, Qiang Ruan
Pages: 1210-1218
Published online on: 27 May 2016

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Article

Using cysteine/cystine to overcome oxidative stress in goat oocytes and embryos cultured in vitro

Zhengrong Zhou, Ruo‑Xin Jia, Guomin Zhang, Yongjie Wan, Yanli Zhang, Yixuan Fan, Ziyu Wang, Pan Huang, Feng Wang
Pages: 1219-1226
Published online on: 10 June 2016

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Article

PRDM8 internal promoter hyperhydroxymethylation correlates with increased expression of the corresponding transcript in Down syndrome

Zhaoning Lu, Yanna Liu, Zhaorui Ren, Jingbin Yan
Pages: 1227-1234
Published online on: 08 June 2016

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Article

Human GPR4 and the Notch signaling pathway in endothelial cell tube formation

Juan Ren, Yuelang Zhang, Hui Cai, Hongbing Ma, Dongli Zhao, Xiaozhi Zhang, Zongfang Li, Shufeng Wang, Jiangsheng Wang, Rui Liu, Yi Li, Jiansheng Qian, Hongxia Wei, Liying Niu, Yan Liu, Lisha Xiao, Muyang Ding, Shiwen Jiang
Pages: 1235-1240
Published online on: 09 June 2016

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Article

Secretory leukocyte protease inhibitor promotes differentiation and mineralization of MC3T3-E1 preosteoblasts on a titanium surface

Baik‑Dong Choi, Seung‑Yeon Lee, Soon‑Jeong Jeong, Do‑Seon Lim, Hee‑Jae Cha, Won‑Gyun Chung, Moon‑Jin Jeong
Pages: 1241-1246
Published online on: 09 June 2016

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Article

Anxiolytic and neuroprotective effects of the Traditional Chinese Medicinal formulation Dan-zhi-xiao-yao-san in a rat model of chronic stress

Guo‑Ping Cao, Dan Gui, Lu‑Di Fu, Zhou‑Ke Guo, Wen‑Jun Fu
Pages: 1247-1254
Published online on: 09 June 2016

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Article

MicroRNA-320 was downregulated in non-small cell lung cancer and inhibited cell proliferation, migration and invasion by targeting fatty acid synthase

Ting Lei, Yuntao Zhu, Chuanfu Jiang, Yu Wang, Junfeng Fu, Zhe Fan, Haiming Qin
Pages: 1255-1262
Published online on: 06 June 2016

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Article

Aberrant Notch signaling in glioblastoma stem cells contributes to tumor recurrence and invasion

Jian‑Bo Yu, Hao Jiang, Ren‑Ya Zhan
Pages: 1263-1268
Published online on: 10 June 2016

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Article

Shikonin stimulates MC3T3-E1 cell proliferation and differentiation via the BMP-2/Smad5 signal transduction pathway

Tao Fang, Qianqian Wu, Shuai Mu, Liyu Yang, Shengye Liu, Qin Fu
Pages: 1269-1274
Published online on: 03 June 2016

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Article

Hydroxychloroquine protects melanocytes from autoantibody-induced injury by reducing the binding of antigen-antibody complexes

Dong‑Guang Li, Wen‑Zhi Hu, Hui‑Jun Ma, Wen Liu, Qing‑Qi Yang, Guang Zhao
Pages: 1275-1282
Published online on: 01 June 2016

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Article

HMGB1 promotes cellular chemokine synthesis and potentiates mesenchymal stromal cell migration via Rap1 activation

Feng Lin, Deting Xue, Tao Xie, Zhijun Pan
Pages: 1283-1289
Published online on: 13 June 2016

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Article

Identification and characteristics of the testes-specific gene, Ccdc38, in mice

Shou‑Ren Lin, Yu‑Chi Li, Man‑Ling Luo, Huan Guo, Tian‑Tian Wang, Jian‑Bo Chen, Qian Ma, Yan‑Li Gu, Zhi‑Mao Jiang, Yao‑Ting Gui
Pages: 1290-1296
Published online on: 03 June 2016

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Article

Latent cytomegalovirus infection exacerbates experimental pulmonary fibrosis by activating TGF-β1

Yonghuai Li, Jian Gao, Guoliang Wang, Guanghe Fei
Pages: 1297-1301
Published online on: 06 June 2016

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Article

Protective effects of BMSCs in combination with erythropoietin in bronchopulmonary dysplasia-induced lung injury

Zhao‑Hua Zhang, Yan-Yan Pan, Rui-Sheng Jing, Yun Luan, Luan Zhang, Chao Sun, Feng Kong, Kai‑Lin Li, Yi‑Biao Wang
Pages: 1302-1308
Published online on: 08 June 2016

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Article

Sirtuin 1 promotes the proliferation of C2C12 myoblast cells via the myostatin signaling pathway

Liang Wang, Ting Zhang, Yongyong Xi, Cuili Yang, Chengcao Sun, Dejia Li
Pages: 1309-1315
Published online on: 27 May 2016

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Article

Icariin promotes cell proliferation and regulates gene expression in human neural stem cells in vitro

Pan Yang, Yun‑Qian Guan, Ya‑Li Li, Li Zhang, Lan Zhang, Lin Li
Pages: 1316-1322
Published online on: 08 June 2016

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Article

Deletion of Nrf2 leads to hepatic insulin resistance via the activation of NF-κB in mice fed a high-fat diet

Zhenxiong Liu, Weijia Dou, Zhen Ni, Qinsheng Wen, Rong Zhang, Ming Qin, Xuxia Wang, Hua Tang, Ying Cao, Jingjie Wang, Shuguang Zhao
Pages: 1323-1331
Published online on: 10 June 2016

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Article

Inhibition of microRNA-155 sensitizes lung cancer cells to irradiation via suppression of HK2-modulated glucose metabolism

Xin Lv, Li Yao, Jianli Zhang, Ping Han, Cuiyun Li
Pages: 1332-1338
Published online on: 10 June 2016

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Article

Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia

Yingjie Zhang, Qi Jiang, Xiaolin Kong, Lili Yang, Wanzhen Hu, Chengfang Lv, Yinghua Li
Pages: 1339-1344
Published online on: 10 June 2016

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Article

Expression of ATP binding cassette E1 enhances viability and invasiveness of lung adenocarcinoma cells in vitro

Ye Tian, Xin Tian, Xu Han, Yong Chen, Cheng‑Yang Song, Yan‑Bin Zhang, Da‑Li Tian
Pages: 1345-1350
Published online on: 10 June 2016

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Article

NR2F2 regulates bone marrow-derived mesenchymal stem cell-promoted proliferation of Reh cells

Ni Zhu, Huafang Wang, Jieping Wei, Binsheng Wang, Wei Shan, Xiaoyu Lai, Yanmin Zhao, Jian Yu, He Huang
Pages: 1351-1356
Published online on: 10 June 2016

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Article

Upregulation of microRNA-206 enhances lipopolysaccharide-induced inflammation and release of amyloid-β by targeting insulin-like growth factor 1 in microglia

Hongxia Xing, Shuangxi Guo, Yi Zhang, Zhiyong Zheng, Haoliang Wang
Pages: 1357-1364
Published online on: 06 June 2016

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Article

Puerarin attenuates inflammation and oxidation in mice with collagen antibody-induced arthritis via TLR4/NF-κB signaling

Changxing Wang, Weidong Wang, Xiaping Jin, Jianguo Shen, Weifeng Hu, Tao Jiang
Pages: 1365-1370
Published online on: 02 June 2016

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Article

COP1 is downregulated in renal cell carcinoma (RCC) and inhibits the migration of RCC ACHN cells in vitro

La Ta, Chengrui Xuan, Nianzeng Xing, Xiaojun Zhu
Pages: 1371-1378
Published online on: 07 June 2016

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Article

Identification and association of RAC1 gene polymorphisms with mRNA and protein expression levels of Rac1 in solid organ (kidney, liver, heart) transplant recipients

Jiali Zhou, Yani Liu, Xiaomei Luo, Rufei Shen, Chunxiao Yang, Tingyu Yang, Shaojun Shi
Pages: 1379-1388
Published online on: 09 June 2016

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Article

A genome wide analysis of alternative splicing events during the osteogenic differentiation of human cartilage endplate-derived stem cells

Jin Shang, Honggang Wang, Xin Fan, Lei Shangguan, Huan Liu
Pages: 1389-1396
Published online on: 02 June 2016

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Article

Berry anthocyanins reduce proliferation of human colorectal carcinoma cells by inducing caspase-3 activation and p21 upregulation

Sirajudheen Anwar, Deborah Fratantonio, Daniela Ferrari, Antonella Saija, Francesco Cimino, Antonio Speciale
Pages: 1397-1403
Published online on: 13 June 2016

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Article

De novo sequencing and analysis of the transcriptome of Panax ginseng in the leaf-expansion period

Shichao Liu, Siming Wang, Meichen Liu, Fei Yang, Hui Zhang, Shiyang Liu, Qun Wang, Yu Zhao
Pages: 1404-1412
Published online on: 08 June 2016

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Article

Clinical significance of RET mutation screening in a pedigree of multiple endocrine neoplasia type 2A

Rongbiao Ying, Jun Feng
Pages: 1413-1417
Published online on: 06 June 2016

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Article

RUNX2 controls human IPO8 basal transcription in Saos-2 cells

Jianjun Xiong, Zhihong Hu, Ting Wang, Xiaoyuan Xu, Jianyun Liu, Ping Wu, Xiangxin Che, Weidong Li
Pages: 1418-1424
Published online on: 01 June 2016

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Article

Adenovirus with p16 gene exerts antitumor effect on laryngeal carcinoma Hep2 cells

Zhengang Yang, Jingxia Hu, Dajun Li, Xinliang Pan
Pages: 1425-1429
Published online on: 01 June 2016

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Article

MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo

Hong‑Li Li, Hui Wu, Bei‑Bei Zhang, Hai‑Lian Shi, Xiao‑Jun Wu
Pages: 1430-1438
Published online on: 03 June 2016

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Article Open Access

Loss of membranous VEGFR1 expression is associated with an adverse phenotype and shortened survival in breast cancer

Patrick Lebok, Julia Huber, Eike‑Christian Burandt, Annette Lebeau, Andreas Holger Marx, Luigi Terracciano, Uwe Heilenkötter, Fritz Jänicke, Volkmar Müller, Peter Paluchowski, Stefan Geist, Christian Wilke, Ronald Simon, Guido Sauter, Alexander Quaas
Pages: 1443-1450
Published online on: 23 June 2016

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Article Open Access

Reciprocal regulation of long noncoding RNAs THBS4‑003 and THBS4 control migration and invasion in prostate cancer cell lines

Jinliang Liu, Gong Cheng, Haiwei Yang, Xiaheng Deng, Chao Qin, Lixin Hua, Changjun Yin
Pages: 1451-1458
Published online on: 23 June 2016

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Article Open Access

Characterization of human bone morphogenetic protein gene variants for possible roles in congenital heart disease

Fei‑Feng Li, Xia Deng, Jing Zhou, Peng Yan, Er‑Ying Zhao, Shu‑Lin Liu
Pages: 1459-1464
Published online on: 23 June 2016

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Article Open Access

Decreasing the ratio of matriptase/HAI‑1 by downregulation of matriptase as a potential adjuvant therapy in ovarian cancer

Pengming Sun, Zhongqing Jiang, Xiaofang Chen, Lifang Xue, Xiaodan Mao, Guanyu Ruan, Yiyi Song, Alexander Mustea
Pages: 1465-1474
Published online on: 23 June 2016

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Article Open Access

Blockade of hypoxia-induced CXCR4 with AMD3100 inhibits production of OA-associated catabolic mediators IL-1β and MMP-13

Pengcui Li, Jin Deng, Xiaochun Wei, Chathuraka T. Jayasuriya, Jingming Zhou, Qian Chen, Jianzhong Zhang, Lei Wei, Fangyuan Wei
Pages: 1475-1482
Published online on: 21 June 2016

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Article Open Access

Identification of differentially expressed genes between lung adenocarcinoma and lung squamous cell carcinoma by gene expression profiling

Chaojing Lu, Hezhong Chen, Zhengxiang Shan, Lixin Yang
Pages: 1483-1490
Published online on: 22 June 2016

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Article Open Access

Contribution of human osteoblasts and macrophages to bone matrix degradation and proinflammatory cytokine release after exposure to abrasive endoprosthetic wear particles

Anika Jonitz‑Heincke, Katrin Lochner, Christoph Schulze, Diana Pohle, Wera Pustlauk, Doris Hansmann, Rainer Bader
Pages: 1491-1500
Published online on: 21 June 2016

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Article Open Access

CMP‑N‑acetylneuraminic acid synthetase interacts with fragile X related protein 1

Yun Ma, Shuai Tian, Zongbao Wang, Changbo Wang, Xiaowei Chen, Wei Li, Yang Yang, Shuya He
Pages: 1501-1508
Published online on: 23 June 2016

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CDKN3 expression is negatively associated with pathological tumor stage and CDKN3 inhibition promotes cell survival in hepatocellular carcinoma

Wei Dai, Huilai Miao, Shuo Fang, Tao Fang, Nianping Chen, Mingyi Li
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Magdy El‑Salhy, Kazuo Umezawa
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Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells

Peng Yang, Jiaying Zhao, Liying Hou, Lei Yang, Kun Wu, Linyou Zhang
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S100A1 transgenic treatment of acute heart failure causes proteomic changes in rats

Yichen Guo, Lianqun Cui, Shiliang Jiang, Dongmei Wang, Shu Jiang, Chen Xie, Yanping Jia
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Biological effects of eukaryotic recombinant plasmid pReceiver-M61-BAI-1 transfection on T24 cells and HUVECs

Da‑Wei Tian, Hai‑Long Hu, Yan Sun, Yang Tang, Ming‑De Lei, Li‑Wei Liu, Rui‑Fa Han, Chang‑Li Wu
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Oncogenic role of microRNA‑20a in human uveal melanoma

Jinzi Zhou, Jian Jiang, Shuhong Wang, Xiaobo Xia
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Decreased expression of Beclin‑1 is significantly associated with a poor prognosis in oral tongue squamous cell carcinoma

Zedong Hu, Zhaoming Zhong, Shaohui Huang, Haojie Wen, Xue Chen, Hongying Chu, Qiuli Li, Chuanzheng Sun
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Neonatal Bacillus Calmette-Guérin vaccination alleviates lipopolysaccharide-induced neurobehavioral impairments and neuroinflammation in adult mice

Junhua Yang, Fangfang Qi, Zhibin Yao
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Screening of gene signatures for rheumatoid arthritis and osteoarthritis based on bioinformatics analysis

Peiheng He, Ziji Zhang, Weiming Liao, Dongliang Xu, Ming Fu, Yan Kang
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Xue Xia Liu, Xiao Fang Shen, Fu‑Jun Liu
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Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats

Jun Yan, Xue Yang, Dong Han, Juan Feng
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Jia-Shen decoction-medicated serum inhibits angiotensin-II induced cardiac fibroblast proliferation via the TGF-β1/Smad signaling pathway

Lin Cui, Youping Wang, Rui Yu, Bin Li, Shiyang Xie, Yuan Gao, Xiaoxiao Wang, Mingjun Zhu
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MBD2 as a novel marker associated with poor survival of patients with hepatocellular carcinoma after hepatic resection

Wei Liu, Na Wang, Min Lu, Xiao‑Juan Du, Bao‑Cai Xing
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Overexpression of Dlx2 leads to postnatal condyle degradation

Jiewen Dai, Jiawen Si, Xiaofang Zhu, Lei Zhang, Dandan Wu, Jingting Lu, Ningjuan Ouyang, Xudong Wang, Guofang Shen
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microRNA-208a in an early stage myocardial infarction rat model and the effect on cAMP-PKA signaling pathway

Gao Feng, Zhang Yan, Chuanchuan Li, Yuemei Hou
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Protein kinase C α is involved in the regulation of AXL receptor tyrosine kinase expression in triple-negative breast cancer cells

Chia‑Herng Yue, Liang‑Chih Liu, Erl‑Shyh Kao, Ho Lin, Li‑Sung Hsu, Chih‑Wei Hsu, Yu‑Yu Lin, Yi‑Syuan Lin, Jer‑Yuh Liu, Chia‑Jen Lee
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Mechanism of osteogenic and adipogenic differentiation of tendon stem cells induced by sirtuin 1

Junpeng Liu, Weifeng Han, Lei Chen, Kanglai Tang
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Impact of activating transcription factor 4 signaling on lipogenesis in HepG2 cells

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Upregulation of p27Kip1 by demethylation sensitizes cisplatin-resistant human ovarian cancer SKOV3 cells

Yan Zhao, Qiaoyan Li, Xiaoying Wu, Puxiang Chen
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Feng Li, Tao Jiang, Wei Liu, Quan Hu, Huinan Yin
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Low levels of TGF-β1 enhance human umbilical cord-derived mesenchymal stem cell fibronectin production and extend survival time in a rat model of lipopolysaccharide-induced acute lung injury

Dong Li, Qingshen Liu, Lei Qi, Xiaoyu Dai, Huan Liu, Yunshan Wang
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The de novo missense mutation N117S in skeletal muscle α‑actin 1 causes a mild form of congenital nemaline myopathy

Liu Yang, Ping Yu, Xiang Chen, Tao Cai
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Jee‑Youn Kim, Yong‑Min An, Jae‑Hoon Park
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IL‑33/ST2 pathway in a bleomycin‑induced pulmonary fibrosis model

Jiao Xu, Jinxu Zheng, Ping Song, Yanjuan Zhou, Shuhong Guan
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Yi Sun, Zhao‑Peng Zheng, Hang Li, Han‑Qun Zhang, Fa‑Qiang Ma
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Importance of activated hepatic stellate cells and angiopoietin-1 in the pathogenesis of hepatocellular carcinoma

Ji‑Zong Lin, Li‑Li Meng, Yan‑Zhu Li, Shu‑Xian Chen, Jian‑Liang Xu, Ya‑Jun Tang, Nan Lin
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Aspirin inhibits glucose‑6‑phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites

Guoqiang Ai, Rakesh Dachineni, D. Ramesh Kumar, Lloyd F. Alfonso, Srinivasan Marimuthu, G. Jayarama Bhat
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Flavonoids from Radix Tetrastigmae improve LPS-induced acute lung injury via the TLR4/MD-2-mediated pathway

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miR-20a induces cisplatin resistance of a human gastric cancer cell line via targeting CYLD

Mingxia Zhu, Xin Zhou, Yiping Du, Zebo Huang, Jun Zhu, Jing Xu, Gongming Cheng, Yongqian Shu, Ping Liu, Wei Zhu, Tongshan Wang
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Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells

Ying Pan, Jieyu Bai, Fangfang Shen, Li Sun, Quanzhong He, Bing Su
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Ipr1 modified BCG as a novel vaccine induces stronger immunity than BCG against tuberculosis infection in mice

Yuwei Wang, Chun Yang, Yonglin He, Xingxing Zhan, Lei Xu
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MicroRNA‑335 inhibits bladder cancer cell growth and migration by targeting mitogen‑activated protein kinase 1

Xiaolin Wang, Guang Wu, Guangxin Cao, Xiaohong Chen, Jian Huang, Xiaohui Jiang, Jianquan Hou
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GSK-3β inhibitor attenuates urinary albumin excretion in type 2 diabetic db/db mice, and delays epithelial-to-mesenchymal transition in mouse kidneys and podocytes

Jia Wan, Peng Li, Dong‑Wei Liu, Ying Chen, Hai‑Zhen Mo, Ben‑Guo Liu, Wen‑Jie Chen, Xiao‑Qing Lu, Jia Guo, Qian Zhang, Ying‑Jin Qiao, Zhang‑Suo Liu, Guang‑Rui Wan
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Recombinant human brain natriuretic peptide attenuates LPS-induced cellular injury in human fetal lung fibroblasts via inhibiting MAPK and NF-κB pathway activation

Zhi Song, Xiu Zhao, Martin Liu, Hongxu Jin, Yan Cui, Mingxiao Hou, Yan Gao
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Positive association of the androgen receptor CAG repeat length polymorphism with the risk of prostate cancer

César Paz‑y‑Miño, Paulo Robles, Carolina Salazar, Paola E. Leone, Jennyfer M. García‑Cárdenas, Manuel Naranjo, Andrés López‑Cortés
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Functional properties of DENV EDIII‑reactive antibodies in human DENV‑1‑infected sera and rabbit antiserum to EDIII

Jing Chen, Kun Wen, Xiao‑Quan Li, Hai‑Su Yi, Xi‑Xia Ding, Yan‑Fen Huang, Yu‑Xian Pan, Dong‑Mei Hu, Biao Di, Xiao‑Yan Che, Ning Fu
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Soy milk digestion extract inhibits progression of prostate cancer cell growth via regulation of prostate cancer‑specific antigen and cell cycle-regulatory genes in human LNCaP cancer cells

Nam‑Hee Kang, Hee‑Chang Shin, Seunghyun Oh, Kyun‑Hee Lee, Yoon‑Bok Lee, Kyung‑Chul Choi
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Bufalin reverses intrinsic and acquired drug resistance to cisplatin through the AKT signaling pathway in gastric cancer cells

Hongyan Zhao, Dali Zhao, Huilin Jin, Hongwei Li, Xiaoying Yang, Liwei Zhuang, Tiefu Liu
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A recombinant plasmid containing CpG motifs as a novel vaccine adjuvant for immune protection against herpes simplex virus 2

Zhuojing He, Juan Xu, Wei Tao, Ting Fu, Fang He, Ruxi Hu, Lan Jia, Yan Hong
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Published online on: 23 June 2016

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Differentially expressed microRNA-218 modulates the viability of renal cell carcinoma by regulating BCL9

Jianming Wang, Yulin Ying, Shumei Bo, Guangjun Li, Fei Yuan
Pages: 1829-1834
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miR-200b inhibits migration and invasion in non-small cell lung cancer cells via targeting FSCN1 Retraction in /10.3892/mmr.2021.12218

Peng Xiao, Wenliang Liu, Hui Zhou
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Sphingosine 1‑phosphate induced by hypoxia increases the expression of PAI‑1 in HepG2 cells via HIF‑1α

Akimasa Sanagawa, Soichiro Iwaki, Moyoko Asai, Daisuke Sakakibara, Hiroaki Norimoto, Burton E. Sobel, Satoshi Fujii
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Type II cGMP‑dependent protein kinase inhibits EGF‑induced JAK/STAT signaling in gastric cancer cells

Min Wu, Yan Wu, Ting Lan, Lu Jiang, Hai Qian, Yongchang Chen
Pages: 1849-1856
Published online on: 27 June 2016

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Mechanism of uncoupling protein 2‑mediated myocardial injury in hypothermic preserved rat hearts

Gai‑Ge Chen, Jin‑Bin Yan, Xu‑Ming Wang, Ming‑Zhi Zheng, Jian‑Ping Jiang, Xin‑Mei Zhou, Bin Cai, Yue‑Liang Shen
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Published online on: 23 June 2016

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Polydatin possesses notable anti‑osteoporotic activity via regulation of OPG, RANKL and β‑catenin

Qi‑Lin Zhou, Ru‑Zi Qin, Yan‑Xin Yang, Kun‑Bing Huang, Xian‑Wen Yang
Pages: 1865-1869
Published online on: 23 June 2016

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

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Yan Shi, Shu-Ai Hou
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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
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Ayman A. Althubity
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Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
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Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
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Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
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Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
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Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
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Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
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Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
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Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
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Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
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Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
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Article

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
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Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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Review Open Access

R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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Article Open Access

PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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Article Open Access

MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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