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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July-2018 Volume 42 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Mechanisms in hypertension and target organ damage: Is the role of the thymus key? (Review)

Xianliang Dai, Li Hua, Yihong Chen, Jiamei Wang, Jingyi Li, Feng Wu, Yanda Zhang, Jiyuan Su, Zonggui Wu, Chun Liang
Pages: 3-12
Published online on: 30 March 2018

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Review

Role of Sirtuin 1 in the pathogenesis of ocular disease (Review)

Mengwen Zhou, Jing Luo, Huiming Zhang
Pages: 13-20
Published online on: 16 April 2018

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Article Open Access

Exploring the molecular mechanisms of osteosarcoma by the integrated analysis of mRNAs and miRNA microarrays

Hao Shen, Wei Wang, Bingbing Ni, Qiang Zou, Hua Lu, Zhanchao Wang
Pages: 21-30
Published online on: 27 March 2018

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Article Open Access

Liuwei Dihuang, a traditional Chinese medicinal formula, inhibits proliferation and migration of vascular smooth muscle cells via modulation of estrogen receptors

Yayun Zhang, Xing Qian, Xin Sun, Chao Lin, Yi Jing, Yuan Yao, Zhi Ma, Meiyu Kuai, Ying Lu, Xueyun Kong, Qi Chen, Xiang Wu, Xuan Zhao, Yu Li, Huimin Bian
Pages: 31-40
Published online on: 16 April 2018

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Article Open Access

Juglanin ameliorates UVB‑induced skin carcinogenesis via anti‑inflammatory and proapoptotic effects in vivo and in vitro

Gui‑Rong Hou, Kang Zeng, Hai‑Mei Lan, Qi Wang
Pages: 41-52
Published online on: 29 March 2018

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Article Open Access

Generation of haploid spermatids from chicken embryonal primordial germ cells

Meng Ji, Shuang Tang, Wenhua Pei, Mingming Ning, Yuehui Ma, Xiangchen Li, Weijun Guan
Pages: 53-60
Published online on: 30 March 2018

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Article Open Access

Glucosamine promotes chondrocyte proliferation via the Wnt/β‑catenin signaling pathway

Yuhuan Ma, Wenwei Zheng, Houhuang Chen, Xiang Shao, Pingdong Lin, Xianxiang Liu, Xihai Li, Hongzhi Ye
Pages: 61-70
Published online on: 22 March 2018

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Article Open Access

Bradykinin potentially stimulates cell proliferation in rabbit corneal endothelial cells through the ZO‑1/ZONAB pathway

Lixian He, Zhou Zhou, Yi Shao, Zhen Yang, Shuangshuang Zhou, Xuexiang Zou, Ying Zhou, Gang Tan
Pages: 71-80
Published online on: 22 March 2018

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Article Open Access

Abnormal expression of fibrosis markers, estrogen receptor α and stromal derived factor‑1/chemokine (C‑X‑C motif) receptor‑4 axis in intrauterine adhesions

Qin Zhou, Xixi Wu, Jianguo Hu, Rui Yuan
Pages: 81-90
Published online on: 22 March 2018

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Article Open Access

Gene microarray analysis of lncRNA and mRNA expression profiles in patients with high‑grade ovarian serous cancer

Yanhui Lou, Huanhuan Jiang, Zhumei Cui, Xiangyu Wang, Lingzhi Wang, Yi Han
Pages: 91-104
Published online on: 23 March 2018

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Article Open Access

Diagnostic and prognostic values of contrast‑enhanced ultrasound combined with diffusion‑weighted magnetic resonance imaging in different subtypes of breast cancer Retraction in /10.3892/ijmm.2020.4484

Gui‑Feng Liu, Zong‑Qiang Wang, Shu‑Hua Zhang, Xue‑Feng Li, Lin Liu, Ying‑Ying Miao, Shao‑Nan Yu
Pages: 105-114
Published online on: 27 March 2018

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Article Open Access

Tripterygium glycoside protects against puromycin amino nucleoside‑induced podocyte injury by upregulating autophagy

Jianguang Gong, Juan Jin, Li Zhao, Yiqiao Li, Yiwen Li, Qiang He
Pages: 115-122
Published online on: 29 March 2018

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Article Open Access

Novel NADPH oxidase inhibitor VAS2870 suppresses TGF‑β‑dependent epithelial‑to‑mesenchymal transition in retinal pigment epithelial cells

Jing Yang, Jing Li, Qun Wang, Yao Xing, Zizhu Tan, Qianyan Kang
Pages: 123-130
Published online on: 03 April 2018

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Article Open Access

Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/‌Akt‑dependent Tbx‑3 activation pathway

Minxia Ke, Quan He, Danping Hong, Ouyang Li, Mengyi  Zhu, Wen‑Bin Ou, Yulong He, Yuehong Wu
Pages: 131-140
Published online on: 03 April 2018

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Article Open Access

miRNA‑222 promotes liver cancer cell proliferation, migration and invasion and inhibits apoptosis by targeting BBC3

Zhichun Liu, Jingwu Sun, Bin Liu, Mengjie Zhao, Entao Xing, Cunshu Dang
Pages: 141-148
Published online on: 20 April 2018

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Article Open Access

Prognostic significance of microsatellite instability‑associated pathways and genes in gastric cancer

Xiaosheng Hang, Dapeng Li, Jianping Wang, Ge Wang
Pages: 149-160
Published online on: 26 April 2018

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Article Open Access

Bromodomain‑containing protein 4 is critical for the antiproliferative and pro‑apoptotic effects of gambogic acid in anaplastic thyroid cancer

Yonghui Wang, Wei Wang, Hongqin Sun
Pages: 161-170
Published online on: 26 April 2018

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Article Open Access

Lack of endogenous parathyroid hormone delays fracture healing by inhibiting vascular endothelial growth factor‑mediated angiogenesis

Qingfeng Ding, Peng Sun, Hao Zhou, Bowen Wan, Jian Yin, Yao Huang, Qingqing Li, Guoyong Yin, Jin Fan
Pages: 171-181
Published online on: 03 April 2018

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Article Open Access

Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress

Yu Wen Lin, Tsung Ying Chen, Chia Yang Hung, Shih Huang Tai, Sheng Yang Huang, Che Chao Chang, Hsin Yi Hung, E Jian Lee
Pages: 182-192
Published online on: 30 March 2018

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Article Open Access

Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS

Hong-Mao Song, Xiang Li, Yuan-Yuan Liu, Wei-Ping Lu, Zhao-Hui Cui, Li Zhou, Di Yao, Hong-Man Zhang
Pages: 193-207
Published online on: 27 March 2018

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Article Open Access

Fisetin-treatment alleviates airway inflammation through inhbition of MyD88/NF-κB signaling pathway

Wei Huang, Ming-Li Li, Ming-Yue Xia, Jian-Ying Shao
Pages: 208-218
Published online on: 22 March 2018

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Article Open Access

Peroxisome proliferator-activated receptor-γ and its related pathway in bone marrow mesenchymal stem cell differentiation co-cultured with mechanically stretched ligament fibroblasts

Bing Zhao, Mengcai Hu, Huiyan Wu, Chenchen Ren, Juan Chen, Xiaodan Zhang, Shihong Cui
Pages: 219-227
Published online on: 20 March 2018

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Article Open Access

miR-19a/b and MeCP2 repress reciprocally to regulate multidrug resistance in gastric cancer cells

Fei Zhu, Qiong Wu, Zhen Ni, Chao Lei, Ting Li, Yongquan Shi
Pages: 228-236
Published online on: 22 March 2018

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Article Open Access

Fisetin administration improves LPS-induced acute otitis media in mouse in vivo

Peng Li, Dan Chen, Yang Huang
Pages: 237-247
Published online on: 22 March 2018

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Article Open Access

Quercetin inhibits NTHi-triggered CXCR4 activation through suppressing IKKα/NF-κB and MAPK signaling pathways in otitis media

Yu-Kun Ma, Yu-Bin Chen, Peng Li
Pages: 248-258
Published online on: 20 March 2018

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Article Open Access

A study of the key genes and inflammatory signaling pathways involved in HLA-B27-associated acute anterior uveitis families

Shuo Yu, Cui Mao, Jinyi Yu, Xin Qi, Jing Wang, Hong Lu
Pages: 259-269
Published online on: 29 March 2018

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Article Open Access

Hypoxia induces endothelial‑mesenchymal transition in pulmonary vascular remodeling

Bo Zhang, Wen Niu, Hai‑Ying Dong, Man‑Ling Liu, Ying Luo, Zhi‑Chao Li
Pages: 270-278
Published online on: 22 March 2018

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Article Open Access

Adenovirus‑mediated knockdown of activin A receptor type 2A attenuates immune‑induced hepatic fibrosis in mice and inhibits interleukin‑17‑induced activation of primary hepatic stellate cells

Hongjun Zhang, Baoling Ju, Ying Nie, Baohui Song, Yuanhong Xu, Ping Gao
Pages: 279-289
Published online on: 29 March 2018

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Article Open Access

Deregulation of microRNA‑31a‑5p is involved in the development of primary hypertension by suppressing apoptosis of pulmonary artery smooth muscle cells via targeting TP53

Qiang Feng, Tao Tian, Junfeng Liu, Li Zhang, Jiangang Qi, Xiaojuan Lin
Pages: 290-298
Published online on: 29 March 2018

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Article Open Access

Bu‑Shen‑Ning‑Xin decoction suppresses osteoclastogenesis by modulating RANKL/OPG imbalance in the CD4+ T lymphocytes of ovariectomized mice

Jia‑Li Zhang, Xue‑Min Qiu, Na Zhang, Wei Tang, Hans‑Jürgen Gober, Da‑Jin Li, Ling Wang
Pages: 299-308
Published online on: 26 April 2018

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Article Open Access

Imaging of immunogold labeling in cells and tissues by helium ion microscopy

Chikara Sato, Mari Sato, Shinichi Ogawa
Pages: 309-321
Published online on: 30 March 2018

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Article Open Access

Low‑intensity pulsed ultrasound promotes periodontal ligament stem cell migration through TWIST1‑mediated SDF‑1 expression Corrigendum in /10.3892/ijmm.2022.5093

Yunji Wang, Jie Li, Ye Qiu, Bo Hu, Jin Chen, Tiwei Fu, Pengfei Zhou, Jinlin Song
Pages: 322-330
Published online on: 27 March 2018

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Article Open Access

Poligoni Multiflori Radix enhances osteoblast formation and reduces osteoclast differentiation

Sang‑Yong Han, Kyung‑Hee Lee, Yun‑Kyung Kim
Pages: 331-345
Published online on: 30 March 2018

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Article Open Access

TIM‑4 blockade of KCs combined with exogenous TGF‑β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts

Hao Wu, Xuesong Xu, Jinzheng Li, Jianping Gong, Min Li
Pages: 346-358
Published online on: 30 March 2018

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Article Open Access

PFK15, a PFKFB3 antagonist, inhibits autophagy and proliferation in rhabdomyosarcoma cells

Chunhui Wang, Jianghong Qu, Siyuan Yan, Quan Gao, Sibin Hao, Dongsheng Zhou
Pages: 359-367
Published online on: 29 March 2018

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Article Open Access

Inflammatory genes are novel prognostic biomarkers for colorectal cancer

Hao Jiang, Li Dong, Fangyan Gong, Yuping Gu, Henghun Zhang, Dong Fan, Zhiguo Sun
Pages: 368-380
Published online on: 18 April 2018

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Article Open Access

miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab10 Retraction in /10.3892/ijmm.2025.5640

Naixin Ding, Xiujin Sun, Tingting Wang, Lei Huang, Jing Wen, Yiqin Zhou
Pages: 381-391
Published online on: 24 April 2018

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Article Open Access

FOXP3 expression is modulated by TGF‑β1/NOTCH1 pathway in human melanoma

Eva Skarmoutsou, Valentina Bevelacqua, Fabio D' Amico, Angela Russo, Demetrios   A. Spandidos, Aurora Scalisi, Grazia Malaponte, Claudio Guarneri
Pages: 392-404
Published online on: 04 April 2018

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Article Open Access

Stanozolol administration combined with exercise leads to decreased telomerase activity possibly associated with liver aging

Eren Ozcagli, Mehtap Kara, Tugba Kotil, Persefoni Fragkiadaki, Manolis N. Tzatzarakis, Christina Tsitsimpikou, Polychronis D. Stivaktakis, Dimitrios Tsoukalas, Demetrios A. Spandidos, Aristides M. Tsatsakis, Buket Alpertunga
Pages: 405-413
Published online on: 26 April 2018

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Article

Antiproliferative effects of imatinib mesylate on ZR‑75‑1 and MDA‑MB‑231 cell lines via PDGFR‑β, PDGF‑BB, c‑Kit and SCF expression Corrigendum in /10.3892/ijmm.2019.4119

Ali Kadivar, Mohamed Ibrahim Noordin, Arya Aditya, Behnam Kamalidehghan, Ehsan Taghizadeh Davoudi, Reihaneh Sedghi, Hamid Akbari Javar
Pages: 414-424
Published online on: 27 March 2018

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Article

Ashwagandha root extract exerts anti‑inflammatory effects in HaCaT cells by inhibiting the MAPK/NF‑κB pathways and by regulating cytokines

Abudubari Sikandan, Takahisa Shinomiya, Yukitoshi Nagahara
Pages: 425-434
Published online on: 02 April 2018

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Article

Histone deacetylase inhibitors alter the expression of molecular markers in breast cancer cells via microRNAs

Yehui Shi, Yongsheng Jia, Weipeng Zhao, Liyan Zhou, Xiaojuan Xie, Zhongsheng Tong
Pages: 435-442
Published online on: 03 April 2018

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Article

Genome-wide analysis of DNA methylation in human peripheral leukocytes identifies potential biomarkers of nonalcoholic fatty liver disease

Rui-Nan Zhang, Qin Pan, Rui-Dan Zheng, Yu-Qiang Mi, Feng Shen, Da Zhou, Guang-Yu Chen, Chan-Yan Zhu, Jian-Gao Fan
Pages: 443-452
Published online on: 22 March 2018

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Article

miR-29b regulates Ang II-induced EMT of rat renal tubular epithelial cells via targeting PI3K/AKT signaling pathway

Hongtao Hu, Shuang Hu, Shen Xu, Yue Gao, Fang Zeng, Hua Shui
Pages: 453-460
Published online on: 22 March 2018

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Article

TWIST1 upregulates miR-214 to promote epithelial-to-mesenchymal transition and metastasis in lung adenocarcinoma

Chao Liu, Jing Luo, Yue-Tao Zhao, Zhong-Yu Wang, Jie Zhou, Shuo Huang, Jia-Ni Huang, Hai-Xia Long, Bo Zhu
Pages: 461-470
Published online on: 17 April 2018

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Article

Plasma cholesterol lowering in an AngII‑infused atherosclerotic mouse model with moderate hypercholesterolemia

Aránzazu Rossignoli, Emina Vorkapic, Anders Wanhainen, Toste Länne, Josefin Skogberg, Erika Folestad, Dick Wågsäter
Pages: 471-478
Published online on: 05 April 2018

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Article

Thromboxane A2 receptor antagonist SQ29548 attenuates SH‑SY5Y neuroblastoma cell impairments induced by oxidative stress

Gaoyu Cai, Aijuan Yan, Ningzhen Fu, Yi Fu
Pages: 479-488
Published online on: 27 March 2018

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Article

lncRNA PVT1 promotes the angiogenesis of vascular endothelial cell by targeting miR‑26b to activate CTGF/ANGPT2

Jifu Zheng, Lili Hu, Jing Cheng, Jing Xu, Zhiqiang Zhong, Yuan Yang, Zheng Yuan
Pages: 489-496
Published online on: 29 March 2018

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Article

Curcumin suppresses MUC5AC production via interfering with the EGFR signaling pathway

Lingling Tang, Qingge Chen, Li Sun, Linyun Zhu, Jinjin Liu, Ziyu Meng, Zhenhua Ni, Xiongbiao Wang
Pages: 497-504
Published online on: 02 April 2018

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Article

RP105 ameliorates hypoxia̸reoxygenation injury in cardiac microvascular endothelial cells by suppressing TLR4̸MAPKs̸NF-κB signaling

Xin Guo, Hong Jiang, Jing Chen, Bo-Fang Zhang, Qi Hu, Shuo Yang, Jian Yang, Jing Zhang
Pages: 505-513
Published online on: 16 April 2018

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Article

Bioinformatics analysis and verification of key genes associated with recurrent respiratory tract infections

Xiang Jin, Zhiyong Ji, Xiaodan Li, Rui Liu, Yinghui Guan
Pages: 514-524
Published online on: 24 April 2018

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Article

Isolation and biological characteristic evaluation of a novel type of cartilage stem/progenitor cell derived from Small‑tailed Han sheep embryos

Caiyun Ma, Tengfei Lu, Hebao Wen, Yanjie Zheng, Xiao Han, Xongda Ji, Weijun Guan
Pages: 525-533
Published online on: 17 April 2018

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Article

Novel zinc‑ and silicon‑phthalocyanines as photosensitizers for photodynamic therapy of cholangiocarcinoma

Jacob Schmidt, Weronika Kuzyniak, Janine Berkholz, Gustav Steinemann, Racheal Ogbodu, Björn Hoffmann, Geraldine Nouailles, Ayşe Gül Gürek, Bianca Nitzsche, Michael Höpfner
Pages: 534-546
Published online on: 16 April 2018

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Article

MicroRNA‑497 attenuates cerebral infarction in patients via the TLR4 and CREB signaling pathways

Si Chen, Wenwei Yin, Kun Bi, Bin Lu
Pages: 547-556
Published online on: 03 April 2018

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Article

IDO decreases glycolysis and glutaminolysis by activating GCN2K, while it increases fatty acid oxidation by activating AhR, thus preserving CD4+ T‑cell survival and proliferation

Theodoros Eleftheriadis, Georgios Pissas, Vassilios Liakopoulos, Ioannis Stefanidis
Pages: 557-568
Published online on: 16 April 2018

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Article

Desoxyrhapontigenin inhibits RANKL‑induced osteoclast formation and prevents inflammation‑mediated bone loss

Phuong Thao Tran, Dong‑Hwa Park, Okhwa Kim, Seung‑Hae Kwon, Byung‑Sun Min, Jeong‑Hyung Lee
Pages: 569-578
Published online on: 17 April 2018

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Article

Emodin inhibits epithelial‑mesenchymal transition and metastasis of triple negative breast cancer via antagonism of CC‑chemokine ligand 5 secreted from adipocytes

Xiaoyun Song, Xiqiu Zhou, Yuenong Qin, Jianfeng Yang, Yu Wang, Zhenping Sun, Kui Yu, Shuai Zhang, Sheng Liu
Pages: 579-588
Published online on: 23 April 2018

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Article

MicroRNA‑221‑3p contributes to cardiomyocyte injury in H2O2‑treated H9c2 cells and a rat model of myocardial ischemia‑reperfusion by targeting p57

Qingfeng Meng, Yang Liu, Xiuyue Huo, Hui Sun, Yingcui Wang, Fangfang Bu
Pages: 589-596
Published online on: 17 April 2018

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Article

Human circular RNA‑0054633 regulates high glucose‑induced vascular endothelial cell dysfunction through the microRNA‑218/roundabout 1 and microRNA‑218/heme oxygenase‑1 axes

Long Pan, Weishuai Lian, Xiaojun Zhang, Shilong Han, Chuanwu Cao, Xue Li, Maoquan Li
Pages: 597-606
Published online on: 16 April 2018

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Article

Adenosine A(2A) receptor activation reverses hypoxia‑induced rat pulmonary artery smooth muscle cell proliferation via cyclic AMP‑mediated inhibition of the SDF1‑CXC4 signaling pathway

Yang Wang, Lei Ying, Ke‑Ke Jin, Yan Nan, Suhua Hu, Xueqin Wu, Ruyi Qi, Xin Luo, Liangxing Wang
Pages: 607-614
Published online on: 16 April 2018

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Article

Inhibitory effects of luteolin‑4'‑O‑β‑D‑glucopyranoside on P2Y12 and thromboxane A2 receptor‑mediated amplification of platelet activation in vitro

Huanjun Xu, Hong Lu, Xiaocui Zhu, Wei Wang, Zhoumiao Zhang, Huizheng Fu, Shuangcheng Ma, Yuehua Luo, Jianjiang Fu
Pages: 615-624
Published online on: 19 April 2018

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Downregulation of Lgr6 inhibits proliferation and invasion and increases apoptosis in human colorectal cancer

Fei Wang, Chun‑Qian Dai, Li‑Rong Zhang, Cao Bing, Jun Qin, Yi‑Fei Liu
Pages: 625-632
Published online on: 18 April 2018

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JMJD6 exerts function in neuropathic pain by regulating NF‑κB following peripheral nerve injury in rats

Cen Wen, Mengyuan Xu, Cheng Mo, Zhigang Cheng, Qulian Guo, Xiaoyan Zhu
Pages: 633-642
Published online on: 03 April 2018

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miR‑152 inhibits rheumatoid arthritis synovial fibroblast proliferation and induces apoptosis by targeting ADAM10 Retraction in /10.3892/ijmm.2021.5007

Jialong Guo, Juan Du, Dan Fei, Jie Xing, Jinxiang Liu, Honghua Lu
Pages: 643-650
Published online on: 20 April 2018

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Bisphosfonate matrix metalloproteinase inhibitors for the treatment of periodontitis: An in vitro study

Marianna De Colli, Paolo Tortorella, Mariangela Agamennone, Cristina Campestre, Fulvio Loiodice, Amelia Cataldi, Susi Zara
Pages: 651-657
Published online on: 25 April 2018

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Effect of hydroxyl group position in flavonoids on inducing single‑stranded DNA damage mediated by cupric ions

Suad Elmegerhi, Cathy Su, Dylan John Buglewicz, Yasushi Aizawa, Takamitsu A Kato
Pages: 658-664
Published online on: 03 April 2018

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Article

MicroRNA‑125 inhibits RKO colorectal cancer cell growth by targeting VEGF

Qi‑Bing Wu, Jing Chen, Jia‑Wei Zhu, Xin Yin, He‑Yang You, Yi‑Rong Lin, Hua‑Qing Zhu
Pages: 665-673
Published online on: 18 April 2018

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Mesenchymal stem cells attenuate doxorubicin‑induced cellular senescence through the VEGF/Notch/TGF‑β signaling pathway in H9c2 cardiomyocytes

Lingli Chen, Wenzheng Xia, Meng Hou
Pages: 674-684
Published online on: 19 April 2018

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Correction Open Access

[Corrigendum] Inhibition of RANKL‑induced osteoclastogenesis through the suppression of the ERK signaling pathway by astragaloside IV and attenuation of titanium‑particle‑induced osteolysis

Mingjun Li, Wengang Wang, Li Geng, Yanru Qin, Wenjie Dong, Xudong Zhang, An Qin, Mingzhi Zhang
Pages: 685-685
Published online on: 03 April 2018

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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