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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2020 Volume 46 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Editorial Open Access

[Editorial] COVID‑19: Post‑lockdown guidelines

Ronald N. Kostoff, Michael B. Briggs, Alan L. Porter, Michael Aschner, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 463-466
Published online on: 12 June 2020

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Review Open Access

Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies (Review)

George Mihai Nitulescu, Horia Paunescu, Sterghios A. Moschos, Dimitrios Petrakis, Georgiana Nitulescu, George Nicolae Daniel Ion, Demetrios A. Spandidos, Taxiarchis Konstantinos Nikolouzakis, Nikolaos Drakoulis, Aristidis Tsatsakis
Pages: 467-488
Published online on: 18 May 2020

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Review Open Access

A dissection of SARS‑CoV2 with clinical implications (Review)

Felician Stancioiu, Georgios Z. Papadakis, Stelios Kteniadakis, Boris Nikovaevich Izotov, Michael D. Coleman, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 489-508
Published online on: 10 June 2020

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Review Open Access

Update on current views and advances on RSV infection (Review)

Ioannis N. Mammas, Simon B. Drysdale, Barbara Rath, Maria Theodoridou, Georgia Papaioannou, Alexia Papatheodoropoulou, Eirini Koutsounaki, Chryssie Koutsaftiki, Eleftheria Kozanidou, Vassilis Achtsidis, Paraskevi Korovessi, George P. Chrousos, Demetrios A. Spandidos
Pages: 509-520
Published online on: 15 June 2020

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Review Open Access

Advance genome editing technologies in the treatment of human diseases: CRISPR therapy (Review)

Meryem Alagoz, Nasim Kherad
Pages: 521-534
Published online on: 19 May 2020

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Review Open Access

Long non‑coding RNAs are novel players in oral inflammatory disorders, potentially premalignant oral epithelial lesions and oral squamous cell carcinoma (Review)

Kaiying Zhang, Wei Qiu, Buling Wu, Fuchun Fang
Pages: 535-545
Published online on: 03 June 2020

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Article Open Access

Placental exosomes isolated from urine of patients with gestational diabetes exhibit a differential profile expression of microRNAs across gestation

Ana Sofía Herrera-Van Oostdam, Juan Carlos Toro‑Ortíz, Jesús Adrián López, Daniel E. Noyola, David Alejandro García‑López, Noé Valentín Durán‑Figueroa, Eduardo Martínez‑Martínez, Diana P. Portales‑Pérez, Mariana Salgado‑Bustamante, Yamilé López‑Hernández
Pages: 546-560
Published online on: 03 June 2020

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Article Open Access

MicroRNA‑93 contributes to the suppression of lung inflammatory responses in LPS‑induced acute lung injury in mice via the TLR4/MyD88/NF‑κB signaling pathway

Hu Gao, Dongqiong Xiao, Linbo Gao, Xihong Li
Pages: 561-570
Published online on: 19 May 2020

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Article Open Access

LINC00473 contributes to the radioresistance of esophageal squamous cell carcinoma by regulating microRNA‑497‑5p and cell division cycle 25A

Wei‑Hua Liu, Han‑Yong Qiao, Jian Xu, Wei‑Qing Wang, Yi‑Lei Wu, Xia Wu
Pages: 571-582
Published online on: 25 May 2020

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Article Open Access

Decitabine attenuates dextran sodium sulfate‑induced ulcerative colitis through regulation of immune regulatory cells and intestinal barrier

Chang Su, Shaoqun Liu, Xiaoying Ma, Xiaotong Yang, Jianwen Liu, Peiyong Zheng, Yiou Cao
Pages: 583-594
Published online on: 18 May 2020

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Article Open Access

Fibroblast‑derived exosomal microRNA‑369 potentiates migration and invasion of lung squamous cell carcinoma cells via NF1‑mediated MAPK signaling pathway

Liping Guo, Baoli Li, Jianjun Yang, Juan Shen, Jinshan Ji, Meijing Miao
Pages: 595-608
Published online on: 22 May 2020

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Article Open Access

Exosomal microRNA‑146a derived from mesenchymal stem cells increases the sensitivity of ovarian cancer cells to docetaxel and taxane via a LAMC2‑mediated PI3K/Akt axis

Liya Qiu, Jiakun Wang, Mei Chen, Fengyun Chen, Wenluo Tu
Pages: 609-620
Published online on: 05 June 2020

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Article Open Access

Circular RNA derived from TIMP2 functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR‑185‑5p and matrix metalloproteinase 2

Wei Guo, Bin Zhang, Chao Sun, Hui‑Quan Duan, Wei‑Xiao Liu, Kun Mu, Ling Zhao, Hao‑Ran Li, Zhan‑Yin Dong, Qing Cui
Pages: 621-632
Published online on: 29 May 2020

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Article Open Access

Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts

Yanfei Du, Haiying Xiao, Jun Wan, Xinyu Wang, Tao Li, Shuzhan Zheng, Jian Feng, Qiang Ye, Jiafu Li, Guang Li, Zhongcai Fan
Pages: 633-640
Published online on: 18 May 2020

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Article Open Access

IL‑27 suppresses airway inflammation, hyperresponsiveness and remodeling via the STAT1 and STAT3 pathways in mice with allergic asthma

Degan Lu, Jiameng Lu, Xiaoqing Ji, Yanbo Ji, Zewen Zhang, Haiying Peng, Fei Sun, Caiqing Zhang
Pages: 641-652
Published online on: 29 May 2020

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Article Open Access

Silencing of long non‑coding antisense RNA brain‑derived neurotrophic factor attenuates hypoxia/ischemia‑induced neonatal brain injury

Li‑Xing Qiao, Rui‑Bin Zhao, Ming‑Fu Wu, Li‑Hua Zhu, Zheng‑Kun Xia
Pages: 653-662
Published online on: 02 June 2020

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Article Open Access

TRAP1 attenuates H9C2 myocardial cell injury induced by extracellular acidification via the inhibition of MPTP opening

Lingxiao Zhang, Lerong Liu, Xia Li, Xing Zhang, Jiangpei Zhao, Yuanyuan Luo, Xiangyu Guo, Tongfeng Zhao
Pages: 663-674
Published online on: 04 June 2020

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Article Open Access

Paeonol exerts anti‑tumor activity against colorectal cancer cells by inducing G0/G1 phase arrest and cell apoptosis via inhibiting the Wnt/β‑catenin signaling pathway

Li‑Hua Liu, Ren‑Jie Shi, Zhi‑Cheng Chen
Pages: 675-684
Published online on: 04 June 2020

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Article Open Access

Knockdown of Tousled‑like kinase 1 inhibits survival of glioblastoma multiforme cells

Kamariah Ibrahim, Nor Azian Abdul Murad, Roslan Harun, Rahman Jamal
Pages: 685-699
Published online on: 28 May 2020

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Article Open Access

Rotenone restrains colon cancer cell viability, motility and epithelial‑mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway Retraction in /10.3892/ijmm.2023.5340

Wenbo Xiao, Yongwei Liu, Maolin Dai, Yu Li, Renqun Peng, Shuangjiang Yu, Hao Liu
Pages: 700-708
Published online on: 10 June 2020

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Article Open Access

miR‑29b promotes the osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue via the PTEN/AKT/β‑catenin signaling pathway

Tian Xia, Shuanghai Dong, Jiwei Tian
Pages: 709-717
Published online on: 22 May 2020

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Article Open Access

Ribonuclease T2 from Aspergillus fumigatus promotes T helper type 2 responses through M2 polarization of macrophages

Jia‑Jie Chen, Yong‑Shen He, Xiao‑Jun Zhong, Ze‑Lang Cai, Yan‑Si Lyu, Zhen‑Fu Zhao, Kunmei Ji
Pages: 718-728
Published online on: 21 May 2020

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Article Open Access

lncRNA DGCR 5/miR‑27a‑3p/BNIP3 promotes cell apoptosis in pancreatic cancer by regulating the p38 MAPK pathway

Xianjie Li, Shanxue Zhou, Tianyi Fan, Xuefeng Feng
Pages: 729-739
Published online on: 04 June 2020

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Article Open Access

MicroRNA‑16 inhibits endometrial stromal cell migration and invasion through suppression of the inhibitor of nuclear factor‑κB kinase subunit β/nuclear factor‑κB pathway

Xiaoping Wang, Rui Ren, Meili Shao, Jun Lan
Pages: 740-750
Published online on: 29 May 2020

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Article Open Access

Simvastatin inhibits the adipogenesis of bone marrow‑derived mesenchymal stem cells through the downregulation of chemerin/CMKLR1 signaling

Yao Guo, Jianzhong Huo, Dou Wu, Haihu Hao, Xinghua Ji, Enzhe Zhao, Boyuan Nie, Qiang Liu
Pages: 751-761
Published online on: 18 May 2020

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Article Open Access

Hypercapnia exacerbates the disruption of the blood‑brain barrier by inducing interleukin‑1β overproduction in the blood of hypoxemic adult rats

Hongguang Ding, Xinqiang Liu, Xusheng Li, Miaoyun Wen, Ya Li, Yongli Han, Linqiang Huang, Mengting Liu, Hongke Zeng
Pages: 762-772
Published online on: 14 May 2020

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Article Open Access

Hyperoxia reduces STX17 expression and inhibits the autophagic flux in alveolar type II epithelial cells in newborn rats

Dan Zhang, Xinyi Zhao, Dingning Zhang, Siyang Gao, Xindong Xue, Jianhua Fu
Pages: 773-781
Published online on: 27 May 2020

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Article Open Access

Upregulation of Nav1.7 by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain

Jun-Jie Tian, Chao-Yang Tan, Qin-Yi Chen, Ying Zhou, Zu-Wei Qu, Meng Zhang, Ke-Tao Ma, Wen-Yan Shi, Li Li, Jun-Qiang Si
Pages: 782-794
Published online on: 20 May 2020

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Article Open Access

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation

Kazi Mohammad Ali Zinnah, Jae‑Won Seol, Sang‑Youel Park
Pages: 795-805
Published online on: 05 June 2020

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Article Open Access

Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Pages: 806-816
Published online on: 04 June 2020

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Article Open Access

Inhibitory effects of brusatol delivered using glycosaminoglycan‑placental chondroitin sulfate A‑modified nanoparticles on the proliferation, migration and invasion of cancer cells

Xin Chen, Tailang Yin, Baozhen Zhang, Beini Sun, Jie Chen, Tianxia Xiao, Baobei Wang, Mengxia Li, Jing Yang, Xiujun Fan
Pages: 817-827
Published online on: 03 June 2020

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Article Open Access

miR‑144‑3p inhibits tumor cell growth and invasion in oral squamous cell carcinoma through the downregulation of the oncogenic gene, EZH2

Longlong He, Lifan Liao, Liangzhi Du
Pages: 828-838
Published online on: 11 June 2020

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Article

CTBP1‑AS2 inhibits proliferation and induces autophagy in ox‑LDL‑stimulated vascular smooth muscle cells by regulating miR‑195‑5p/ATG14

Yang Wang, Cheng‑Xin Zhang, Sheng‑Lin Ge, Wen‑Hui Gong
Pages: 839-848
Published online on: 02 June 2020

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Article

Preliminary research on the effects and mechanisms of umbilical cord‑derived mesenchymal stem cells in streptozotocin‑induced diabetic retinopathy Corrigendum in /10.3892/ijmm.2020.4708

Ken Zhao, Jie Liu, Gang Dong, Huan Xia, Pingan Wang, Xuan Xiao, Zhen Chen
Pages: 849-858
Published online on: 01 June 2020

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Article

Long non‑coding RNA RP11‑340F14.6 promotes a shift in the Th17/Treg ratio by binding with P2X7R in juvenile idiopathic arthritis

Na Huang, Zhidan Fan, Le Ma, Huihui Ma, Hui Huang, Haiguo Yu, Xiaoyu Zhou
Pages: 859-868
Published online on: 27 May 2020

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Article

Recombinant programmed cell death 1 inhibits psoriatic inflammation in imiquimod‑treated mice

Shiguang Peng, Mei Cao, Xiaoying Sun, Yaqiong Zhou, Chu‑Yen Chen, Tian Ma, Hongjin Li, Bin Li, Bo Zhu, Xin Li
Pages: 869-879
Published online on: 21 May 2020

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Article

IL‑18 knockout alleviates atopic dermatitis‑like skin lesions induced by MC903 in a mouse model

Jia‑Long Chen, Xue‑Li Niu, Ya‑Li Gao, Lei Ma, Xing‑Hua Gao, Hong‑Duo Chen, Rui‑Qun Qi
Pages: 880-888
Published online on: 04 June 2020

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Article

Sevoflurane preconditioning inhibits cardiomyocyte injury induced by oxygen‑glucose deprivation by modulating TXNIP

Meina Ma, Rui Li, Wenbo Sun, Qi Wang, Hong Yu, Hongmei Yu
Pages: 889-897
Published online on: 11 June 2020

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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Review Open Access

mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Article Open Access

Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Review Open Access

Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Review Open Access

Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Review Open Access

Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Review Open Access

Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Review Open Access

Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Review Open Access

Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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