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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2020 Volume 46 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Editorial Open Access

[Editorial] COVID‑19: Post‑lockdown guidelines

Ronald N. Kostoff, Michael B. Briggs, Alan L. Porter, Michael Aschner, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 463-466
Published online on: 12 June 2020

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Review Open Access

Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies (Review)

George Mihai Nitulescu, Horia Paunescu, Sterghios A. Moschos, Dimitrios Petrakis, Georgiana Nitulescu, George Nicolae Daniel Ion, Demetrios A. Spandidos, Taxiarchis Konstantinos Nikolouzakis, Nikolaos Drakoulis, Aristidis Tsatsakis
Pages: 467-488
Published online on: 18 May 2020

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Review Open Access

A dissection of SARS‑CoV2 with clinical implications (Review)

Felician Stancioiu, Georgios Z. Papadakis, Stelios Kteniadakis, Boris Nikovaevich Izotov, Michael D. Coleman, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 489-508
Published online on: 10 June 2020

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Review Open Access

Update on current views and advances on RSV infection (Review)

Ioannis N. Mammas, Simon B. Drysdale, Barbara Rath, Maria Theodoridou, Georgia Papaioannou, Alexia Papatheodoropoulou, Eirini Koutsounaki, Chryssie Koutsaftiki, Eleftheria Kozanidou, Vassilis Achtsidis, Paraskevi Korovessi, George P. Chrousos, Demetrios A. Spandidos
Pages: 509-520
Published online on: 15 June 2020

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Review Open Access

Advance genome editing technologies in the treatment of human diseases: CRISPR therapy (Review)

Meryem Alagoz, Nasim Kherad
Pages: 521-534
Published online on: 19 May 2020

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Review Open Access

Long non‑coding RNAs are novel players in oral inflammatory disorders, potentially premalignant oral epithelial lesions and oral squamous cell carcinoma (Review)

Kaiying Zhang, Wei Qiu, Buling Wu, Fuchun Fang
Pages: 535-545
Published online on: 03 June 2020

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Article Open Access

Placental exosomes isolated from urine of patients with gestational diabetes exhibit a differential profile expression of microRNAs across gestation

Ana Sofía Herrera-Van Oostdam, Juan Carlos Toro‑Ortíz, Jesús Adrián López, Daniel E. Noyola, David Alejandro García‑López, Noé Valentín Durán‑Figueroa, Eduardo Martínez‑Martínez, Diana P. Portales‑Pérez, Mariana Salgado‑Bustamante, Yamilé López‑Hernández
Pages: 546-560
Published online on: 03 June 2020

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Article Open Access

MicroRNA‑93 contributes to the suppression of lung inflammatory responses in LPS‑induced acute lung injury in mice via the TLR4/MyD88/NF‑κB signaling pathway

Hu Gao, Dongqiong Xiao, Linbo Gao, Xihong Li
Pages: 561-570
Published online on: 19 May 2020

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Article Open Access

LINC00473 contributes to the radioresistance of esophageal squamous cell carcinoma by regulating microRNA‑497‑5p and cell division cycle 25A

Wei‑Hua Liu, Han‑Yong Qiao, Jian Xu, Wei‑Qing Wang, Yi‑Lei Wu, Xia Wu
Pages: 571-582
Published online on: 25 May 2020

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Article Open Access

Decitabine attenuates dextran sodium sulfate‑induced ulcerative colitis through regulation of immune regulatory cells and intestinal barrier

Chang Su, Shaoqun Liu, Xiaoying Ma, Xiaotong Yang, Jianwen Liu, Peiyong Zheng, Yiou Cao
Pages: 583-594
Published online on: 18 May 2020

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Article Open Access

Fibroblast‑derived exosomal microRNA‑369 potentiates migration and invasion of lung squamous cell carcinoma cells via NF1‑mediated MAPK signaling pathway

Liping Guo, Baoli Li, Jianjun Yang, Juan Shen, Jinshan Ji, Meijing Miao
Pages: 595-608
Published online on: 22 May 2020

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Article Open Access

Exosomal microRNA‑146a derived from mesenchymal stem cells increases the sensitivity of ovarian cancer cells to docetaxel and taxane via a LAMC2‑mediated PI3K/Akt axis

Liya Qiu, Jiakun Wang, Mei Chen, Fengyun Chen, Wenluo Tu
Pages: 609-620
Published online on: 05 June 2020

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Article Open Access

Circular RNA derived from TIMP2 functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR‑185‑5p and matrix metalloproteinase 2

Wei Guo, Bin Zhang, Chao Sun, Hui‑Quan Duan, Wei‑Xiao Liu, Kun Mu, Ling Zhao, Hao‑Ran Li, Zhan‑Yin Dong, Qing Cui
Pages: 621-632
Published online on: 29 May 2020

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Article Open Access

Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts

Yanfei Du, Haiying Xiao, Jun Wan, Xinyu Wang, Tao Li, Shuzhan Zheng, Jian Feng, Qiang Ye, Jiafu Li, Guang Li, Zhongcai Fan
Pages: 633-640
Published online on: 18 May 2020

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Article Open Access

IL‑27 suppresses airway inflammation, hyperresponsiveness and remodeling via the STAT1 and STAT3 pathways in mice with allergic asthma

Degan Lu, Jiameng Lu, Xiaoqing Ji, Yanbo Ji, Zewen Zhang, Haiying Peng, Fei Sun, Caiqing Zhang
Pages: 641-652
Published online on: 29 May 2020

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Article Open Access

Silencing of long non‑coding antisense RNA brain‑derived neurotrophic factor attenuates hypoxia/ischemia‑induced neonatal brain injury

Li‑Xing Qiao, Rui‑Bin Zhao, Ming‑Fu Wu, Li‑Hua Zhu, Zheng‑Kun Xia
Pages: 653-662
Published online on: 02 June 2020

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Article Open Access

TRAP1 attenuates H9C2 myocardial cell injury induced by extracellular acidification via the inhibition of MPTP opening

Lingxiao Zhang, Lerong Liu, Xia Li, Xing Zhang, Jiangpei Zhao, Yuanyuan Luo, Xiangyu Guo, Tongfeng Zhao
Pages: 663-674
Published online on: 04 June 2020

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Article Open Access

Paeonol exerts anti‑tumor activity against colorectal cancer cells by inducing G0/G1 phase arrest and cell apoptosis via inhibiting the Wnt/β‑catenin signaling pathway

Li‑Hua Liu, Ren‑Jie Shi, Zhi‑Cheng Chen
Pages: 675-684
Published online on: 04 June 2020

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Article Open Access

Knockdown of Tousled‑like kinase 1 inhibits survival of glioblastoma multiforme cells

Kamariah Ibrahim, Nor Azian Abdul Murad, Roslan Harun, Rahman Jamal
Pages: 685-699
Published online on: 28 May 2020

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Article Open Access

Rotenone restrains colon cancer cell viability, motility and epithelial‑mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway Retraction in /10.3892/ijmm.2023.5340

Wenbo Xiao, Yongwei Liu, Maolin Dai, Yu Li, Renqun Peng, Shuangjiang Yu, Hao Liu
Pages: 700-708
Published online on: 10 June 2020

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Article Open Access

miR‑29b promotes the osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue via the PTEN/AKT/β‑catenin signaling pathway

Tian Xia, Shuanghai Dong, Jiwei Tian
Pages: 709-717
Published online on: 22 May 2020

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Article Open Access

Ribonuclease T2 from Aspergillus fumigatus promotes T helper type 2 responses through M2 polarization of macrophages

Jia‑Jie Chen, Yong‑Shen He, Xiao‑Jun Zhong, Ze‑Lang Cai, Yan‑Si Lyu, Zhen‑Fu Zhao, Kunmei Ji
Pages: 718-728
Published online on: 21 May 2020

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Article Open Access

lncRNA DGCR 5/miR‑27a‑3p/BNIP3 promotes cell apoptosis in pancreatic cancer by regulating the p38 MAPK pathway

Xianjie Li, Shanxue Zhou, Tianyi Fan, Xuefeng Feng
Pages: 729-739
Published online on: 04 June 2020

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Article Open Access

MicroRNA‑16 inhibits endometrial stromal cell migration and invasion through suppression of the inhibitor of nuclear factor‑κB kinase subunit β/nuclear factor‑κB pathway

Xiaoping Wang, Rui Ren, Meili Shao, Jun Lan
Pages: 740-750
Published online on: 29 May 2020

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Article Open Access

Simvastatin inhibits the adipogenesis of bone marrow‑derived mesenchymal stem cells through the downregulation of chemerin/CMKLR1 signaling

Yao Guo, Jianzhong Huo, Dou Wu, Haihu Hao, Xinghua Ji, Enzhe Zhao, Boyuan Nie, Qiang Liu
Pages: 751-761
Published online on: 18 May 2020

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Article Open Access

Hypercapnia exacerbates the disruption of the blood‑brain barrier by inducing interleukin‑1β overproduction in the blood of hypoxemic adult rats

Hongguang Ding, Xinqiang Liu, Xusheng Li, Miaoyun Wen, Ya Li, Yongli Han, Linqiang Huang, Mengting Liu, Hongke Zeng
Pages: 762-772
Published online on: 14 May 2020

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Article Open Access

Hyperoxia reduces STX17 expression and inhibits the autophagic flux in alveolar type II epithelial cells in newborn rats

Dan Zhang, Xinyi Zhao, Dingning Zhang, Siyang Gao, Xindong Xue, Jianhua Fu
Pages: 773-781
Published online on: 27 May 2020

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Article Open Access

Upregulation of Nav1.7 by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain

Jun-Jie Tian, Chao-Yang Tan, Qin-Yi Chen, Ying Zhou, Zu-Wei Qu, Meng Zhang, Ke-Tao Ma, Wen-Yan Shi, Li Li, Jun-Qiang Si
Pages: 782-794
Published online on: 20 May 2020

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Article Open Access

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation

Kazi Mohammad Ali Zinnah, Jae‑Won Seol, Sang‑Youel Park
Pages: 795-805
Published online on: 05 June 2020

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Article Open Access

Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Pages: 806-816
Published online on: 04 June 2020

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Article Open Access

Inhibitory effects of brusatol delivered using glycosaminoglycan‑placental chondroitin sulfate A‑modified nanoparticles on the proliferation, migration and invasion of cancer cells

Xin Chen, Tailang Yin, Baozhen Zhang, Beini Sun, Jie Chen, Tianxia Xiao, Baobei Wang, Mengxia Li, Jing Yang, Xiujun Fan
Pages: 817-827
Published online on: 03 June 2020

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Article Open Access

miR‑144‑3p inhibits tumor cell growth and invasion in oral squamous cell carcinoma through the downregulation of the oncogenic gene, EZH2

Longlong He, Lifan Liao, Liangzhi Du
Pages: 828-838
Published online on: 11 June 2020

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Article

CTBP1‑AS2 inhibits proliferation and induces autophagy in ox‑LDL‑stimulated vascular smooth muscle cells by regulating miR‑195‑5p/ATG14

Yang Wang, Cheng‑Xin Zhang, Sheng‑Lin Ge, Wen‑Hui Gong
Pages: 839-848
Published online on: 02 June 2020

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Article

Preliminary research on the effects and mechanisms of umbilical cord‑derived mesenchymal stem cells in streptozotocin‑induced diabetic retinopathy Corrigendum in /10.3892/ijmm.2020.4708

Ken Zhao, Jie Liu, Gang Dong, Huan Xia, Pingan Wang, Xuan Xiao, Zhen Chen
Pages: 849-858
Published online on: 01 June 2020

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Article

Long non‑coding RNA RP11‑340F14.6 promotes a shift in the Th17/Treg ratio by binding with P2X7R in juvenile idiopathic arthritis

Na Huang, Zhidan Fan, Le Ma, Huihui Ma, Hui Huang, Haiguo Yu, Xiaoyu Zhou
Pages: 859-868
Published online on: 27 May 2020

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Article

Recombinant programmed cell death 1 inhibits psoriatic inflammation in imiquimod‑treated mice

Shiguang Peng, Mei Cao, Xiaoying Sun, Yaqiong Zhou, Chu‑Yen Chen, Tian Ma, Hongjin Li, Bin Li, Bo Zhu, Xin Li
Pages: 869-879
Published online on: 21 May 2020

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Article

IL‑18 knockout alleviates atopic dermatitis‑like skin lesions induced by MC903 in a mouse model

Jia‑Long Chen, Xue‑Li Niu, Ya‑Li Gao, Lei Ma, Xing‑Hua Gao, Hong‑Duo Chen, Rui‑Qun Qi
Pages: 880-888
Published online on: 04 June 2020

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Article

Sevoflurane preconditioning inhibits cardiomyocyte injury induced by oxygen‑glucose deprivation by modulating TXNIP

Meina Ma, Rui Li, Wenbo Sun, Qi Wang, Hong Yu, Hongmei Yu
Pages: 889-897
Published online on: 11 June 2020

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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