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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2021 Volume 24 Issue 6

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Medial tunica degeneration of the ascending aortic wall is associated with specific microRNA changes in bicuspid aortic valve disease

Calogera Pisano, Antonella Marino Gammazza, Francesca Rappa, Rosario Barone, Rosalinda Allegro, Alessandro Pitruzzella, Alessia Tagliavia, Virginia Agostara, Giovanni Ruvolo, Francesco Cappello, Vincenzo Argano
Article Number: 876
Published online on: 29 October 2021

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Review

Cardioprotective effects of hydrogen sulfide in attenuating myocardial ischemia‑reperfusion injury (Review)

Dan Wu, Yijing Gu, Deqiu Zhu
Article Number: 875
Published online on: 29 October 2021

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Article Open Access

Biological evaluation of linalool on the function of blood vessels

Yunyu Liang, Yan Zhong, Xinmei Li, Yingying Xiao, Yu Wu, Pingchang  Xie
Article Number: 874
Published online on: 28 October 2021

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Article Open Access

Ginsenoside Rh2 stimulates the production of mitochondrial reactive oxygen species and induces apoptosis of cervical cancer cells by inhibiting mitochondrial electron transfer chain complex

Ying Liu, Shiting Yu, Xin Xing, Juhui Qiao, Yiqiu Yin, Jiawen Wang, Meichen Liu, Wei Zhang
Article Number: 873
Published online on: 28 October 2021

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Article Open Access

Knockdown of lncRNA MEG8 inhibits cell proliferation and invasion, but promotes cell apoptosis in hemangioma, via miR‑203‑induced mediation of the Notch signaling pathway

Zhenfeng Hu, Xiangmei Liu, Jing Guo, Lei Zhuo, Yongdong Chen, Haojun Yuan
Article Number: 872
Published online on: 27 October 2021

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Review Open Access

Research methods for animal models of atherosclerosis (Review)

Yali Zhang, Mahreen Fatima, Siyuan Hou, Liang Bai, Sihai Zhao, Enqi Liu
Article Number: 871
Published online on: 27 October 2021

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Article Open Access

lncRNA KCNQ1OT1 may function as a competitive endogenous RNA in atrial fibrillation by sponging miR‑223‑3p

Weiran Dai, Xiaoying Chao, Zhiyuan Jiang, Guoqiang Zhong
Article Number: 870
Published online on: 25 October 2021

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Article

Role of Thrombospondin‑1 in sepsis‑induced myocardial injury Corrigendum in /10.3892/mmr.2023.13000

Yun Xie, Jiaxiang Zhang, Wei Jin, Rui Tian, Ruilan Wang
Article Number: 869
Published online on: 25 October 2021

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Article Open Access

All‑trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury

Shuangxue Li, Yuansheng Lei, Jieyun Lei, Hui Li
Article Number: 868
Published online on: 21 October 2021

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Article Open Access

Knockdown of TRIM9 attenuates irinotecan‑induced intestinal mucositis in IEC‑6 cells by regulating DUSP6 expression via the P38 pathway Retraction in /10.3892/mmr.2025.13504

Wenjun Zhao, Qingming Wang
Article Number: 867
Published online on: 20 October 2021

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Review Open Access

Multi‑faceted role of cancer‑associated adipocytes in the tumor microenvironment (Review)

Huihui Yao, Songbing He
Article Number: 866
Published online on: 20 October 2021

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Article Open Access

MicroRNA‑200c‑3p suppresses intervertebral disc degeneration by targeting RAP2C/ERK signaling

Jianping Cao, Meng Jiang, Huafeng Ren, Kai Xu
Article Number: 865
Published online on: 20 October 2021

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Article

Exosomal microRNA‑302a promotes trophoblast migration and proliferation, and represses angiogenesis by regulating the expression levels of VEGFA in preeclampsia

Maoqin Wu, Yongqiang Zhao, Lun Li, Gang Wang, Lin Xing
Article Number: 864
Published online on: 19 October 2021

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Retraction Open Access

[Retracted] Knockdown of AQP1 inhibits growth and invasion of human ovarian cancer cells

Yanli Wang, Yanyan Fan, Chunhua Zheng, Xiaomeng Zhang
Article Number: 863
Published online on: 19 October 2021

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Article Open Access

Pleckstrin 2 is a potential drug target for colorectal carcinoma with activation of APC/β‑catenin

Bao Chai, Yarong Guo, Na Zhu, Junmei Jia, Zhuowei Zhang, Mei Ping, Kai Jia, Xiaolong Cui, Yuhong Suo
Article Number: 862
Published online on: 19 October 2021

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Article Open Access

Circular RNA hsa_circ_105039 promotes cardiomyocyte differentiation by sponging miR‑17 to regulate cyclinD2 expression

Boshi Yu, Mengmeng Li, Shu Ping Han, Zhangbin Yu, Jingai Zhu
Article Number: 861
Published online on: 19 October 2021

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Article Open Access

Peroxisome proliferator‑activated receptor β/δ regulates cerebral vasospasm after subarachnoid hemorrhage via modulating vascular smooth muscle cells phenotypic conversion

Li Xu, Jiang Wu, Yuan Liu, Gang Chen, Chao Ma, Hongrong Zhang
Article Number: 860
Published online on: 19 October 2021

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Article Open Access

Gomisin M2 alleviates psoriasis‑like skin inflammation by inhibiting inflammatory signaling pathways

Namkyung Kim, Soyoung Lee, Jinjoo Kang, Taeg Kyu Kwon, Dongwoo Khang, Sang-Hyun Kim
Article Number: 859
Published online on: 19 October 2021

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Review Open Access

Current treatment strategies for COVID‑19 (Review)

Fabin Han, Yanming Liu, Mei Mo, Juanli Chen, Cheng Wang, Yong Yang, Jibiao Wu
Article Number: 858
Published online on: 15 October 2021

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Article Open Access

hsa‑miR‑429 targets CBX8 to promote cell apoptosis in diffuse large B‑cell lymphoma

Yan Liang, Zhuo-Jun Yu, Min Liu, Hui-Min Liu, Jiang-Zhao Zhang, Tao Xiong, Yuan-Yan Tang, Zhi-Ping Huang
Article Number: 857
Published online on: 14 October 2021

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Article Open Access

Upregulation of CCT3 promotes cervical cancer progression through FN1

Lei Dou, Xinxin Zhang
Article Number: 856
Published online on: 14 October 2021

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Article Open Access

FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1β-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway

Huajie Mao, Bin Han, Hao Li, Yiqing Tao, Weigang Wu
Article Number: 855
Published online on: 14 October 2021

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Review

Sarcopenia, frailty and type 2 diabetes mellitus (Review)

Hiroki Nishikawa, Shinya Fukunishi, Akira Asai, Keisuke Yokohama, Hideko Ohama, Shuhei Nishiguchi, Kazuhide Higuchi
Article Number: 854
Published online on: 14 October 2021

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Article Open Access

miR‑302d‑3p regulates the viability, migration and apoptosis of breast cancer cells through regulating the TMBIM6‑mediated ERK signaling pathway

Yanru Liao, Zhenxiong Qiu, Ling Bai
Article Number: 853
Published online on: 14 October 2021

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Article Open Access

Diallyl sulfide protects against dilated cardiomyopathy via inhibition of oxidative stress and apoptosis in mice

Shuo Pang, Wei Dong, Ning Liu, Shan Gao, Jing Li, Xu Zhang, Dan Lu, Lianfeng Zhang
Article Number: 852
Published online on: 13 October 2021

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Article Open Access

Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria‑dependent apoptosis pathway Corrigendum in /10.3892/mmr.2026.13849

Ping Niu, Yuxuan Sun, Shiyi Wang, Guang Li, Xiaomin Tang, Jiaqiang Sun, Chunchen Pan, Jingwu Sun
Article Number: 851
Published online on: 13 October 2021

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Article Open Access

Protective multi‑target effects of DL‑3‑n‑butylphthalide combined with 3‑methyl‑1‑phenyl‑2‑pyrazolin‑5‑one in mice with ischemic stroke

Yali Guan, Pengfei Li, Yingshuo Liu, Lan Guo, Qingwen Wu, Yuefa Cheng
Article Number: 850
Published online on: 12 October 2021

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Review Open Access

DNA barcode to trace the development and differentiation of cord blood stem cells (Review)

Mo-Yu Wang, Yang Zhou, Guang-Shun Lai, Qi Huang, Wen-Qi Cai, Zi-Wen Han, Yingying Wang, Zhaowu Ma, Xian-Wang Wang, Ying Xiang, Shu-Xian Fang, Xiao-Chun Peng, Hong-Wu Xin
Article Number: 849
Published online on: 12 October 2021

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Article Open Access

Role of tumor necrosis factor receptor‑associated factor 6 in pyroptosis during acute pancreatitis

Biwei Wei, Yahui Gong, Huiying Yang, Jie Zhou, Zhou Su, Zhihai Liang
Article Number: 848
Published online on: 11 October 2021

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Review

Tumor necrosis factor inhibitors as therapeutic agents for recurrent spontaneous abortion (Review)

Hong Wu, Qingxia You, Yi Jiang, Fangxiang Mu
Article Number: 847
Published online on: 11 October 2021

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Article Open Access

Silencing long noncoding RNA LINC01138 inhibits aerobic glycolysis to reduce glioma cell proliferation by regulating the microRNA‑375/SP1 axis

Chengning Xu, Haoran Yin, Xi Jiang, Chunming Sun
Article Number: 846
Published online on: 11 October 2021

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Article Open Access

Long non‑coding RNA HHIP‑AS1 inhibits lung cancer epithelial‑mesenchymal transition and stemness by regulating PCDHGA9

Zhuanzhuan Zhou, Yanping Lai, Shan Cao, Qifang Zhuo, Huiqin Tang
Article Number: 845
Published online on: 11 October 2021

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Article Open Access

NEP1‑40 promotes myelin regeneration via upregulation of GAP‑43 and MAP‑2 expression after focal cerebral ischemia in rats Corrigendum in /10.3892/mmr.2023.12945

Hong Zhao, Zhen-Dong Liu, Yong-Bo Zhang, Xiao-Yu Gao, Cui Wang, Yi Liu, Xun-Fen Wang
Article Number: 844
Published online on: 11 October 2021

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Article

Long non­‑coding RNA SNHG16 functions as a tumor activator by sponging miR‑373‑3p to regulate the TGF‑β‑R2/SMAD pathway in prostate cancer

Wubin Weng, Changming Liu, Guomin Li, Qiongfang Ruan, Huizhang Li, Ningfeng Lin, Guangbing Chen
Article Number: 843
Published online on: 11 October 2021

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Article Open Access

Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues

Peng Xu, Yali Yi, Yijing Luo, Zhicheng Liu, Yilin Xu, Jing Cai, Zhimin Zeng, Anwen Liu
Article Number: 842
Published online on: 11 October 2021

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Article

Endostatin inhibits the proliferation and migration of B16 cells by inducing macrophage polarity to M1‑type

Hua Guo, Longyuan Zhou, Jun Guo, Xueqin Huang, Junlian Gu
Article Number: 841
Published online on: 11 October 2021

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Article Open Access

Tong‑fu‑li‑fei decoction attenuates immunosuppression to protect the intestinal‑mucosal barrier in sepsis by inhibiting the PD‑1/PD‑L1 signaling pathway

Li Chen, Lan Li, Suzhao Zou, Qianhua Liao, Bo Lv
Article Number: 840
Published online on: 11 October 2021

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Review Open Access

Mental depression: Relation to different disease status, newer treatments and its association with COVID-19 pandemic (Review)

Mohamed S. Abdel-Bakky, Elham Amin, Tarek M. Faris, Ahmed A.H. Abdellatif
Article Number: 839
Published online on: 08 October 2021

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Article Open Access

FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway Corrigendum in /10.3892/mmr.2023.12998

Anna Li, Shuxian Li, Chongyu Zhang, Zhenya Fang, Yaqiong Sun, Yanjie Peng, Xietong Wang, Meihua Zhang
Article Number: 838
Published online on: 04 October 2021

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Article Open Access

Astaxanthin induces NADPH oxidase activation and receptor‑interacting protein kinase 1‑mediated necroptosis in gastric cancer AGS cells

Sori Kim, Hanbit Lee, Joo Weon Lim, Hyeyoung Kim
Article Number: 837
Published online on: 04 October 2021

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Retraction Open Access

[Retracted] Oncolytic adenovirus‑mediated mda‑7/IL‑24 expression suppresses osteosarcoma growth and enhances sensitivity to doxorubicin

Zongming Liu, Libo Xu, Hongping Yuan, Yang Zhang, Xiaona Zhang, Dongxu Zhao
Article Number: 836
Published online on: 04 October 2021

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Article Open Access

Spinal cord stimulation reduces cardiac pain through microglial deactivation in rats with chronic myocardial ischemia

Jian Wang, Xiao-Chen Wu, Ming-Ming Zhang, Jia-Hao Ren, Yi Sun, Jing-Zhen Liu, Xi-Qiang Wu, Si-Yi He, Yun-Qing Li, Jin-Bao Zhang
Article Number: 835
Published online on: 01 October 2021

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Article Open Access

Proteomics changes after negative pressure wound therapy in diabetic foot ulcers

Zeguo Jia, Lei Liu, Shiqi Zhang, Xiaotong Zhao, Li Luo, Yizhong Tang, Bing Shen, Mingwei Chen
Article Number: 834
Published online on: 01 October 2021

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Article Open Access

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway Retraction in /10.3892/mmr.2025.13449

Xianjun Wang, Baocheng Yang, Yuyu Li, Jiye Luo, Yanli Wang
Article Number: 833
Published online on: 30 September 2021

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Article Open Access

Formononetin ameliorates IL‑13‑induced inflammation and mucus formation in human nasal epithelial cells by activating the SIRT1/Nrf2 signaling pathway

Juanjuan Huang, Xianfeng Chen, Aihua Xie
Article Number: 832
Published online on: 30 September 2021

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Article Open Access

FOXP4 promotes laryngeal squamous cell carcinoma progression through directly targeting LEF‑1

Jian Shi, Jingtian Wang, Hongkun Cheng, Shenghui Liu, Xiaowei Hao, Lili Lan, Gancun Wu, Meng Liu, Yan Zhao
Article Number: 831
Published online on: 28 September 2021

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Article Open Access

CMBs carrying PTX and CRISPR/Cas9 targeting C‑erbB‑2 plasmids interfere with endometrial cancer cells

Siyuan Peng, Junhong Cai, Shan Bao
Article Number: 830
Published online on: 28 September 2021

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Article Open Access

MAPK inhibitors protect against early‑stage osteoarthritis by activating autophagy

Chun-Na Lan, Wei-Jun Cai, Jie Shi, Zhong-Jie Yi
Article Number: 829
Published online on: 28 September 2021

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Article Open Access

Cholesterol biosynthesis inhibitor RO 48‑8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway

Zhen Ding, Yanan Gu, Dake Huang, Hong Zhou, Tingting Zhu, Xin Luo, Sumei Zhang, Shengquan Zhang, Yeben Qian
Article Number: 828
Published online on: 28 September 2021

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Article Open Access

Lycopus lucidus Turcz ameliorates DNCB‑induced atopic dermatitis in BALB/c mice

Ga-Yul Min, Eun-Young Kim, Sooyeon Hong, Jae-Hyun Kim, Minsun Kim, Eom Ji Kim, Jae Ho Park, Youngjoo Sohn, Hyuk-Sang Jung
Article Number: 827
Published online on: 27 September 2021

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Article Open Access

RHBDD1 promotes proliferation, migration, invasion and EMT in renal cell carcinoma via the EGFR/AKT signaling pathway

Mingyang Li, Licheng Cai, Xingyuan Wang, Yipeng Yu, Wengang Jian, Guochang Bao, Zhiming Gao, Junsheng Guo, Jian Zhang, Chunsheng Li, Cheng Zhang
Article Number: 826
Published online on: 27 September 2021

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Article Open Access

Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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Retraction Open Access

[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Article Open Access

Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Article Open Access

Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Review Open Access

Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Article Open Access

Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Article

Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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Article Open Access

A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Article Open Access

Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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Review Open Access

SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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