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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2018 Volume 40 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Circular RNAs: Crucial regulators in the human body (Review)

Yuanyong Wang, Tong Lu, Qian Wang, Jia Liu, Wenjie Jiao
Pages: 3119-3135
Published online on: 25 September 2018

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Review

The application of prostate specific membrane antigen in CART‑cell therapy for treatment of prostate carcinoma (Review)

Kifayat Ullah, Frank Addai Peprah, Feng Yu, Haifeng Shi
Pages: 3136-3143
Published online on: 01 October 2018

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Article Open Access

Inhibition of pancreatic cancer stem cells by Rauwolfia vomitoria extract

Ruochen Dong, Ping Chen, Qi Chen
Pages: 3144-3154
Published online on: 18 September 2018

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Article Open Access

Gene module analysis of juvenile myelomonocytic leukemia and screening of anticancer drugs

Wencheng Zhao, Lin Wang, Yongbin Yu
Pages: 3155-3170
Published online on: 18 September 2018

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Article Open Access

Downregulation of miR‑224‑5p in prostate cancer and its relevant molecular mechanism via TCGA, GEO database and in silico analyses

Bin‑Liang Gan, Li‑Jie Zhang, Li Gao, Fu‑Chao Ma, Rong‑Quan He, Gang Chen, Jie Ma, Jin‑Cai Zhong, Xiao‑Hua Hu
Pages: 3171-3188
Published online on: 03 October 2018

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Article Open Access

Survival analysis of genome-wide profiles coupled with Connectivity Map database mining to identify potential therapeutic targets for cholangiocarcinoma

Peng Lin, Xiao-Zhu Zhong, Xiao-Dong Wang, Jian-Jun Li, Rui-Qi Zhao, Yu He, Yan-Qiu Jiang, Xian-Wen Huang, Gang Chen, Yun He, Hong Yang
Pages: 3189-3198
Published online on: 18 September 2018

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Article Open Access

Identification of potential prognostic long non‑coding RNA signatures based on a competing endogenous RNA network in lung adenocarcinoma

Xiaojuan Wang, Yawen Ding, Bangming Da, Yan Fei, Gang Feng
Pages: 3199-3212
Published online on: 21 September 2018

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Article Open Access

Xanthohumol, a prenylated flavonoid from Hops, exerts anticancer effects against gastric cancer in vitro

Shanshan Wei, Taoli Sun, Jie Du, Bikui Zhang, Daxiong Xiang, Wenqun Li
Pages: 3213-3222
Published online on: 21 September 2018

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Article Open Access

Antitumor effects and mechanisms of olaparib in combination with carboplatin and BKM120 on human triple‑negative breast cancer cells

Hui Zhao, Qianxi Yang, Yunhui Hu, Jin Zhang
Pages: 3223-3234
Published online on: 20 September 2018

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Article Open Access

Capsaicin and sorafenib combination treatment exerts synergistic anti‑hepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling

Ninggao Dai, Ruifan Ye, Qikuan He, Pengyi Guo, Hao Chen, Qiyu Zhang
Pages: 3235-3248
Published online on: 01 October 2018

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Article Open Access

Identification of a novel biomarker in tangeretin‑induced cell death in AGS human gastric cancer cells

Silvia Yumnam, Suchismita Raha, Seong Min Kim, Venu Venkatarame Gowda Saralamma, Ho Jeong Lee, Sang Eun Ha, Jeong Doo Heo, Sang Joon Lee, Eun Hee Kim, Won Sup Lee, Jin A. Kim, Gon Sup Kim
Pages: 3249-3260
Published online on: 24 September 2018

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Article Open Access

miR‑29a suppresses the growth and metastasis of hepatocellular carcinoma through IFITM3

Yiming Liang, Enliang Li, Jiaqi Min, Chengwu Gong, Jun Gao, Jiyuan Ai, Wenjun Liao, Linquan Wu
Pages: 3261-3272
Published online on: 28 September 2018

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Article Open Access

TRIM14 promotes the migration and invasion of gastric cancer by regulating epithelial‑to‑mesenchymal transition via activation of AKT signaling regulated by miR‑195‑5p

Feiqian Wang, Litao Ruan, Jinru Yang, Qiaoling Zhao, Wei Wei
Pages: 3273-3284
Published online on: 28 September 2018

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Article Open Access

Downregulation of RNF138 inhibits cellular proliferation, migration, invasion and EMT in glioma cells via suppression of the Erk signaling pathway Corrigendum in /10.3892/or.2022.8337

Haibin Wu, Xuetao Li, Ming Feng, Lin Yao, Zhitong Deng, Guozheng Zao, Youxin Zhou, Sansong Chen, Ziwei Du
Pages: 3285-3296
Published online on: 28 September 2018

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Article Open Access

Cellular communication promotes mammosphere growth and collective invasion through microtubule‑like structures and angiogenesis

Shangke Huang, Na Yuan, Guanying Wang, Fang Wu, Lu Feng, Minna Luo, Miao Li, Anqi Luo, Xinhan Zhao, Lingxiao Zhang
Pages: 3297-3312
Published online on: 09 October 2018

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Article Open Access

Knockdown of arsenic resistance protein 2 inhibits human glioblastoma cell proliferation through the MAPK/ERK pathway

Xiao‑Xue Ke, Yi Pang, Kuijun Chen, Dunke Zhang, Feng Wang, Shunqin Zhu, Jingxin Mao, Xiaosong Hu, Guanghui Zhang, Hongjuan Cui
Pages: 3313-3322
Published online on: 09 October 2018

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Article Open Access

Inhibition of miR‑194 suppresses the Wnt/β‑catenin signalling pathway in gastric cancer

Yin Peng, Xiaojing Zhang, Huijuan Lin, Shiqi Deng, Yong Huang, Ying  Qin, Xianling Feng, Ruibin Yan, Yanqiu Zhao, Yulan Cheng, Yanjie Wei, Jian Wang, Wangchun Chen, Xinmin Fan, Hassan Ashktorab, Duane Smoot, Stephen J. Meltzer, Song Li, Zhong Zhang, Zhe Jin
Pages: 3323-3334
Published online on: 08 October 2018

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Article

Lymphocyte‑derived microparticles stimulate osteoclastogenesis by inducing RANKL in fibroblasts of odontogenic keratocysts

Qi‑Wen Man, Lin‑Zhou Zhang, Yi Zhao, Jin‑Yuan Liu, Yue‑Yu Zheng, Yi‑Fang Zhao, Bing Liu
Pages: 3335-3345
Published online on: 18 September 2018

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Article

Genomic analysis of small nucleolar RNAs identifies distinct molecular and prognostic signature in hepatocellular carcinoma

Hong Yang, Peng Lin, Hua‑Yu Wu, Hai‑Yuan Li, Yun He, Yi‑Wu Dang, Gang Chen
Pages: 3346-3358
Published online on: 18 September 2018

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Article Open Access

Gene expression differences between thyroid carcinoma, thyroid adenoma and normal thyroid tissue

Quan Wang, Yilin Shen, Bin Ye, Haixia Hu, Cui Fan, Tan Wang, Yuqin Zheng, Jingrong Lv, Yan Ma, Mingliang Xiang
Pages: 3359-3369
Published online on: 20 September 2018

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Article Open Access

Antitumor effects of the silencing of programmed cell death ligand 1 in colorectal cancer via immunoregulation

Yilin Chen, Ying Huang, Xingrong Lu, Gaoxiong Wang, Pan Chi
Pages: 3370-3380
Published online on: 26 September 2018

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Article Open Access

Autophagy is positively associated with the accumulation of myeloid‑derived suppressor cells in 4‑nitroquinoline‑1‑oxide‑induced oral cancer

Jia‑Shun Wu, Li Li, Sha‑Sha Wang, Xin Pang, Jing‑Biao Wu, Su‑Rui Sheng, Ya‑Jie Tang, Ya‑Ling Tang, Min Zheng, Xin‑Hua Liang
Pages: 3381-3391
Published online on: 28 September 2018

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Article Open Access

Increased resistin suggests poor prognosis and promotes development of lung adenocarcinoma Retraction in /10.3892/or.2023.8595

Cui‑Cui Zhao, Jing Chen, Rui‑Fang Niu, Yan Liu, Chuan‑Gui Zhang
Pages: 3392-3404
Published online on: 26 September 2018

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Article Open Access

Non‑thermal plasma inhibits tumor growth and proliferation and enhances the sensitivity to radiation in vitro and in vivo

Lin Lin, Lili Wang, Yandong Liu, Chao Xu, Yu Tu, Juying Zhou
Pages: 3405-3415
Published online on: 28 September 2018

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Article Open Access

MicroRNA‑424 serves an anti‑oncogenic role by targeting cyclin‑dependent kinase 1 in breast cancer cells

Dan Xie, Hongming Song, Tianqi Wu, Dengfeng Li, Kaiyao Hua, Hui Xu, Bingkun Zhao, Chenyang Wu, Jiashu Hu, Changle Ji, Yijun Deng, Lin Fang
Pages: 3416-3426
Published online on: 27 September 2018

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Article Open Access

Novel three‑lncRNA signature predicts survival in patients with pancreatic cancer

Bin Wu, Kaixuan Wang, Janguo Fei, Yi Bao, Xiaoguang Wang, Zhengwei Song, Fei Chen, Jun Gao, Zhengxiang Zhong
Pages: 3427-3437
Published online on: 03 October 2018

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Article Open Access

Tumor‑released lncRNA H19 promotes gefitinib resistance via packaging into exosomes in non‑small cell lung cancer Retraction in /10.3892/or.2025.8973

Yi Lei, Wang Guo, Bowang Chen, Lu Chen, Jiaxin Gong, Weimin Li
Pages: 3438-3446
Published online on: 03 October 2018

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Article Open Access

Inhibiting TrxR suppresses liver cancer by inducing apoptosis and eliciting potent antitumor immunity

Hong Lei, Guan Wang, Jian Zhang, Qiuju Han
Pages: 3447-3457
Published online on: 27 September 2018

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Article Open Access

Pectolinarigenin inhibits non‑small cell lung cancer progression by regulating the PTEN/PI3K/AKT signaling pathway

Fei Xu, Xuan Gao, Huiyun Pan
Pages: 3458-3468
Published online on: 02 October 2018

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Article

MicroRNA‑433 inhibits cell growth and induces apoptosis in human cervical cancer through PI3K/AKT signaling by targeting FAK

Jie Xu, Weipei Zhu, Lijuan Chen, Lili Liu
Pages: 3469-3478
Published online on: 21 September 2018

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Article

miR‑144‑3p regulates the resistance of lung cancer to cisplatin by targeting Nrf2

Yan Yin, Hua Liu, Junhui Xu, Dongsheng Shi, Liang Zhai, Bin Liu, Lei Wang, Guangxin Liu, Jianwen Qin
Pages: 3479-3488
Published online on: 08 October 2018

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Article

Altered mRNA expression levels of the major components of sphingolipid metabolism, ceramide synthases and their clinical implication in colorectal cancer

Sung Won Jang, Woo‑Jae Park, Hyeonji Min, Taeg Kyu Kwon, Seong Kyu Baek, Ilseon Hwang, Shin Kim, Jong‑Wook Park
Pages: 3489-3500
Published online on: 18 September 2018

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Article

Metformin suppresses hypoxia‑induced migration via the HIF‑1α/VEGF pathway in gallbladder cancer in vitro and in vivo Corrigendum in /10.3892/or.2019.7101

Jianwen Ye, Kunlun Chen, Lei Qi, Renfeng Li, Hongwei Tang, Chuang Zhou, Wenlong Zhai
Pages: 3501-3510
Published online on: 28 September 2018

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Article

TCGA dataset‑based construction and integrated analysis of aberrantly expressed long non‑coding RNA mediated competing endogenous RNA network in gastric cancer

Wenting He, Dachuan Zhang, Xiaodong Li, Jun Wu, Xuanxuan Yang, Qi Wang, Wenbin Lu, Jingting Jiang, Changping Wu
Pages: 3511-3522
Published online on: 21 September 2018

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Article

miRNA‑26a‑5p and miR‑26b‑5p inhibit the proliferation of bladder cancer cells by regulating PDCD10

Ke Wu, Xing‑Yu Mu, Jun‑Tao Jiang, Ming‑Yue Tan, Ren‑Jie Wang, Wen‑Jie Zhou, Xiang Wang, Yin‑Yan He, Ming‑Qing Li, Zhi‑Hong Liu
Pages: 3523-3532
Published online on: 26 September 2018

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Article

Downregulation of glucose‑6‑phosphate dehydrogenase by microRNA‑1 inhibits the growth of pituitary tumor cells

Chao He, Jun Yang, Jiawang Ding, Song Li, Hui Wu, Yan Xiong, Fei Zhou, Yurong Jiang, Lin Teng, Jian Yang
Pages: 3533-3542
Published online on: 01 October 2018

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Article

Silibinin attenuates TGF‑β1‑induced migration and invasion via EMT suppression and is associated with COX‑2 downregulation in bladder transitional cell carcinoma

Feng Li, Yi Sun, Jing Jia, Chao Yang, Xiaoshuang Tang, Ben Jin, Ke Wang, Peng Guo, Zhenkun Ma, Yule Chen, Xinyang Wang, Luke Chang, Dalin He, Jin Zeng
Pages: 3543-3550
Published online on: 21 September 2018

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Article

Identification of key tumorigenesis‑related genes and their microRNAs in colon cancer

Binbin Xie, Rongjie Zhao, Bingjun Bai, Yuhui Wu, Yuzi Xu, Si Lu, Yong Fang, Zhanggui Wang, Ewetse Paul Maswikiti, Xiaoyun Zhou, Hongming Pan, Weidong Han
Pages: 3551-3560
Published online on: 21 September 2018

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Article

Upregulation of microRNA‑300 induces the proliferation of liver cancer by downregulating transcription factor FOXO1

Yuanhong Chang, Cancan Zhou, Lin Fan, Guanglin Qiu, Guanghui Wang, Guangbing Wei, Xinming Chang, Xuqi Li
Pages: 3561-3572
Published online on: 21 September 2018

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Article

Associations of gene‑wide SNPs in SNAI1 and TWIST1 with breast cancer and ovarian cancer susceptibility among Chinese Han women

Ya‑Jun Wang, Li‑Yuan Zheng, Zi‑Fan Wang, Rui Song, Li Yang, Yue‑Hang Geng, Fang Mei, Yun‑Tao Xie, Lan Chen, Dong‑Ge Liu, Xiang‑Hong Li, Ying‑Li Sun, Xin‑Xia Tian, Wei‑Gang Fang
Pages: 3573-3584
Published online on: 21 September 2018

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Article

MicroRNA‑744 inhibits migration and invasion of hepatocellular carcinoma cells by targeting SOX12 Retraction in /10.3892/or.2022.8364

Wei Zhang, Kai Liu, Songyang Liu, Bai Ji, Yahui Liu
Pages: 3585-3592
Published online on: 08 October 2018

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Article

Lymphoma transformation of tumor infiltrating lymphocytes observed in testicular patient‑derived xenograft models

K. Kalavska, L. Kucerova, S. Schmidtova, L. Toro, Z. Kozovska, L. Plank, M. Chovanec, P. Palacka, D. Pindak, D. Macak, J. Mardiak, M. Mego
Pages: 3593-3602
Published online on: 05 October 2018

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Article

Berberine induces mitochondrial‑mediated apoptosis and protective autophagy in human malignant pleural mesothelioma NCI‑H2452 cells

Zhouhong Yao, Yunyan Wan, Bin Li, Congcong Zhai, Fei Yao, Yanmeng Kang, Qinghua Liu, Dianjie Lin
Pages: 3603-3610
Published online on: 01 October 2018

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Article

Combination of serum microRNAs and ultrasound profile as predictive biomarkers of diagnosis and prognosis for papillary thyroid microcarcinoma

Yanqing Zhang, Jiaqi Pan, Desheng Xu, Zhengkai Yang, Jingxue Sun, Lulu Sun, Yanmeizhi Wu, Hong Qiao
Pages: 3611-3624
Published online on: 09 October 2018

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Article

Long non-coding RNA FOXD2-AS1 plays an oncogenic role in hepatocellular carcinoma by targeting miR‑206

Yuanhong Chang, Jie Zhang, Cancan Zhou, Guanglin Qiu, Guanghui Wang, Shufeng Wang, Xinming Chang, Xuqi Li, Lin Fan
Pages: 3625-3634
Published online on: 28 September 2018

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Article Open Access

Histone deacetylase SIRT6 regulates chemosensitivity in liver cancer cells via modulation of FOXO3 activity

Jia‑Qing Hu, Fang Deng, Xiao‑Ping Hu, Wei Zhang, Xiao‑Chen Zeng, Xue‑Fei Tian
Pages: 3635-3644
Published online on: 08 October 2018

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Article

Gap junction β‑2 expression is negatively associated with the estrogen receptor status in breast cancer tissues and is a regulator of breast tumorigenesis

Abhijith Shettar, Surekha Damineni, Geetashree Mukherjee, Paturu Kondaiah
Pages: 3645-3653
Published online on: 03 October 2018

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Article

MicroRNA‑495 regulates human gastric cancer cell apoptosis and migration through Akt and mTOR signaling

Jun Wang, Weiwei Feng, Yuanqiang Dong, Xiang Mao, Fenghua Guo, Fen Luo
Pages: 3654-3662
Published online on: 21 September 2018

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Article

Mangiferin induces radiosensitization in glioblastoma cells by inhibiting nonhomologous end joining

Faguang Mu, Ting Liu, Hanrui Zheng, Xiaofang Xie, Tiantian Lei, Xia He, Suya Du, Rongsheng Tong, Yi Wang
Pages: 3663-3673
Published online on: 01 October 2018

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Article

Systemic immune response associated with radiation therapy in B‑cell non‑Hodgkin's lymphoma of Waldeyer's ring

Xingjian Niu, Hongfei Ji, Yiran Wang, Songliu Hu, Qijia Xuan, Lan Huang, Lei Yin, Wenjia Su, Liru Li, Han Zhang, Jingtong Li, Yue Yang, Weiwei An, Qingyuan Zhang
Pages: 3674-3684
Published online on: 28 September 2018

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Article

IL‑23 concentration‑dependently regulates T24 cell proliferation, migration and invasion and is associated with prognosis in patients with bladder cancer

Peng Wang, Yao Zhang, Jun Zhang, Jun Jiang, Fengshuo Jin, Zhongyi Sun
Pages: 3685-3693
Published online on: 08 October 2018

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Article

Mitochondrial DNA D‑loop lesions with the enhancement of DNA repair contribute to gastrointestinal cancer progression

Bishi Wang, Luxin Qiao, Yuhe Wang, Jing Zeng, Dexi Chen, Hongliang Guo, Yulin Zhang
Pages: 3694-3704
Published online on: 21 September 2018

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Article

miR-182 controls cell growth in gastrointestinal stromal tumors by negatively regulating CYLD expression

Tianlong Ling, Fengrong Yu, Hui Cao
Pages: 3705-3713
Published online on: 03 October 2018

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Article

Bortezomib improves adoptive carbonic anhydrase IX‑specific chimeric antigen receptor‑modified NK92 cell therapy in mouse models of human renal cell carcinoma

Qing Zhang, Jinjing Xu, Jiage Ding, Hongyan Liu, Huizhong Li, Hailong Li, Mengmeng Lu, Yangna Miao, Zhenzhen Wang, Qiang Fu, Junnian Zheng
Pages: 3714-3724
Published online on: 24 September 2018

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Article

Clinical associations between ASCT2 and p‑mTOR in the pathogenesis and prognosis of epithelial ovarian cancer

Huiming Guo, Yu Xu, Feng Wang, Zongwen Shen, Xiaoyu Tuo, Hong Qian, Huawe Wang, Kunhua Wang
Pages: 3725-3733
Published online on: 24 September 2018

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Article

MiR‑381 regulates cell motility, growth and colony formation through PIK3CA in endometriosis‑associated clear cell and endometrioid ovarian cancer

Chia‑Yi Hsu, Tsung‑Hua Hsieh, Tze‑Kiong Er, Hung‑Sheng Chen, Ching‑Chou Tsai, Eing‑Mei Tsai
Pages: 3734-3742
Published online on: 09 October 2018

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Article

Taurolidine promotes cell apoptosis by enhancing GRIM‑19 expression in liver cancer

Feifei Li, Jianni Qi, Chengyong Qin, Zhaoqing Fu, Wanhua Ren
Pages: 3743-3751
Published online on: 18 September 2018

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Article

Radioresistant breast cancer cells exhibit increased resistance to chemotherapy and enhanced invasive properties due to cancer stem cells

Young Shin Ko, Hana Jin, Jong Sil Lee, Sang Won Park, Ki Churl Chang, Ki Mun Kang, Bae Kwon Jeong, Hye Jung Kim
Pages: 3752-3762
Published online on: 18 September 2018

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Article

Long intergenic non‑protein coding RNA 152 promotes multiple myeloma progression by negatively regulating microRNA‑497 Retraction in /10.3892/or.2021.8239

Tianhua Yu, Zhihua Xu, Xuanhe Zhang, Lan Men, Haiying Nie
Pages: 3763-3771
Published online on: 21 September 2018

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Article

Copine 5 expression predicts prognosis following curative resection of esophageal squamous cell carcinoma

Shinichi Umeda, Mitsuro Kanda, Masahiko Koike, Haruyoshi Tanaka, Takashi Miwa, Chie Tanaka, Daisuke Kobayashi, Masaya Suenaga, Masamichi Hayashi, Suguru Yamada, Goro Nakayama, Yasuhiro Kodera
Pages: 3772-3780
Published online on: 27 September 2018

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Article

Effects of 60 kDa prolactin and estradiol on metabolism and cell survival in cervical cancer: Co‑expression of their hormonal receptors during cancer progression

Annie Riera‑Leal, Adrián Ramírez De Arellano, Inocencia Guadalupe Ramírez‑López, Edgar I. Lopez‑Pulido, Judith R. Dávila Rodríguez, José G. Macías‑Barragan, Pablo César Ortiz‑Lazareno, Luis Felipe Jave‑Suárez, Cristina Artaza‑Irigaray, Susana Del Toro Arreola, Margarita Montoya‑Buelna, José Francisco Muñoz‑Valle, Ana Laura Pereira‑Suárez
Pages: 3781-3793
Published online on: 28 September 2018

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Article

Upregulation of thyroid hormone receptor interactor 13 is associated with human hepatocellular carcinoma

Linling Ju, Xuefeng Li, Jianguo Shao, Rujian Lu, Yifan Wang, Zhaolian Bian
Pages: 3794-3802
Published online on: 04 October 2018

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Article

MicroRNA‑mRNA integrated analysis based on a case of well‑differentiated thyroid cancer with both metastasis and metastatic recurrence

Yun‑Jie Zhang, Yu‑Shui Ma, Qing Xia, Fei Yu, Zhong‑Wei Lv, Cheng‑You Jia, Xiao‑Xin Jiang, Liang Zhang, Yun‑Chao Shao, Wen‑Ting Xie, Gai‑Xia Lu, Xia‑Qing Yv, Peng Zhong, Da Fu, Xiao‑Feng Wang
Pages: 3803-3811
Published online on: 26 September 2018

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Article

JIB‑04 induces cell apoptosis via activation of the p53/Bcl‑2/caspase pathway in MHCC97H and HepG2 cells

Weiguo Liao, Jie Liu, Bin Liu, Xiaojie Huang, Yongxin Yin, De Cai, Mingyi Li, Runzhi Zhu
Pages: 3812-3820
Published online on: 26 September 2018

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Article

Downregulation of miR‑200c‑3p contributes to the resistance of breast cancer cells to paclitaxel by targeting SOX2

Junqing Chen, Wei Tian, Haifei He, Feng Chen, Jian Huang, Xiaojia Wang, Zhanhong Chen
Pages: 3821-3829
Published online on: 26 September 2018

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Article

Text mining‑based drug discovery in cutaneous squamous cell carcinoma

Yuyan Pan, Yong Zhang, Jiaqi Liu
Pages: 3830-3842
Published online on: 28 September 2018

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Article

Cancer stem cell biomarkers for head and neck squamous cell carcinoma: A bioinformatic analysis

Meng Xiao, Liu Liu, Shijian Zhang, Xi Yang, Yan'an Wang
Pages: 3843-3851
Published online on: 08 October 2018

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Article

Expression of KLF9 in pancreatic cancer and its effects on the invasion, migration, apoptosis, cell cycle distribution, and proliferation of pancreatic cancer cell lines

Zhiwei Zhong, Fan Zhou, Dong Wang, Mingming Wu, Weimin Zhou, Yeqing Zou, Jie Li, Linquan Wu, Xiangbao Yin
Pages: 3852-3860
Published online on: 02 October 2018

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Article

DNA methylation of neural EGFL like 1 (NELL1) is associated with advanced disease and the metastatic state of renal cell cancer patients

Inga Peters, Natalia Dubrowinskaja, Jörg Hennenlotter, Wiebke Inga Antonopoulos, Christoph A.J. Von Klot, Hossein Tezval, Arnulf Stenzl, Markus A. Kuczyk, Jürgen Serth
Pages: 3861-3868
Published online on: 24 September 2018

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Article

L‑Deprenyl exerts cytotoxicity towards acute myeloid leukemia through inhibition of mitochondrial respiration

Ilhwan Ryu, Min Jeong Ryu, Jeongsu Han, Soo Jeong Kim, Min Joung Lee, Xianshu Ju, Byeong Hyeon Yoo, Yu Lim Lee, Yunseon Jang, Ik‑Chan Song, Woosuk Chung, Eungseok Oh, Jun Young Heo, Gi Ryang Kweon
Pages: 3869-3878
Published online on: 01 October 2018

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Article

Anti‑osteopontin autoantibodies in various types of cancer

Lamyaa Kadhim Alsarkhi, Georg F. Weber
Pages: 3879-3889
Published online on: 05 October 2018

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Article

MicroRNA‑466 inhibits the aggressive behaviors of hepatocellular carcinoma by directly targeting metadherin Retraction in /10.3892/or.2022.8357

Chen Jia, Desheng Tang, Chen Sun, Lei Yao, Fujun Li, Yanhua Hu, Xinchen Zhang, Dequan Wu
Pages: 3890-3898
Published online on: 03 October 2018

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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