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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2022 Volume 24 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Bleomycin‑based electrochemotherapy for the treatment of a Buschke‑Löwenstein tumor (perianal giant condyloma) in an HIV‑positive kidney transplant recipient: A case report

Francesco Russano, Irene Russo, Paolo Del Fiore, Claudia Di Prata, Simone Mocellin, Mauro Alaibac
Article Number: 466
Published online on: 07 November 2022

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Review Open Access

Cancer stem cells markers in ovarian cancer: Clinical and therapeutic significance (Review)

Patrycja Królewska-Daszczyńska, Dominika Wendlocha, Marta Smycz-Kubańska, Sebastian Stępień, Aleksandra Mielczarek-Palacz
Article Number: 465
Published online on: 07 November 2022

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Case Report Open Access

EBV‑positive large‑cell and small‑cell neuroendocrine carcinoma of the nasopharynx: A case report and review of the literature

Zhen Su, Hao Wen Yan, Guo Rong Zou
Article Number: 464
Published online on: 07 November 2022

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Article Open Access

Biomarkers for anti‑vascular endothelial growth factor drugs

Sho Kuriyama, Takeshi Yamada, Akihisa Matsuda, Goro Takahashi, Takuma Iwai, Kohki Takeda, Koji Ueda, Toshimitsu Miyasaka, Yasuyuki Yokoyama, Seiichi Shinji, Hiromichi Sonoda, Ryo Ohta, Kazuhide Yonaga, Shintaro Kanaka, Hiroshi Yoshida
Article Number: 463
Published online on: 07 November 2022

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Article Open Access

Heat shock protein 20 suppresses breast carcinogenesis by inhibiting the MAPK and AKT signaling pathways

Yinxi Yang, Yifeng Wu, Lihong Hou, Xin Ge, Guoquan Song, Hongdou Jin
Article Number: 462
Published online on: 03 November 2022

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Review Open Access

FOXK2 transcription factor and its roles in tumorigenesis (Review)

Zhaojun Wang, Xinling Liu, Zhanju Wang, Zhenbo Hu
Article Number: 461
Published online on: 03 November 2022

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Article Open Access

Potential of blood exosomal ENAH, SEPT9, EGF, MMP‑9 and CXCL8 for the early screening of breast cancer

Zijing Zhang, Hongying Wang, Yiting Jin, Chengyu Chu, Jinsong Bai, Juntian Huang, Lemei Yang, Feng Tang, Liping Zou, Shuyang Wang, Qiang Zou
Article Number: 460
Published online on: 03 November 2022

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Case Report Open Access

Synchronous mantle cell lymphoma bone marrow involvement complicated with extensive‑stage small cell lung cancer: A case report and literature review

Nengwen Xu, Zhimin Fan, Weie Liu, Cangjian Zhang, Junyu Zhang, Linjie Li
Article Number: 459
Published online on: 02 November 2022

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Case Report Open Access

Near complete remission of a locally advanced giant melanoma of the vulva following hypo‑fractionated radiotherapy and immune checkpoint inhibitors: A case report

Shuang Chen, Xuemei Deng, Chen Xie, Qingke Dong, Hongru Yang
Article Number: 458
Published online on: 02 November 2022

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Article Open Access

Suppressive effect of YY1‑mediated RGS22 regulation on the proliferation, migration and invasion of pancreatic ductal adenocarcinoma

Shou-Ji Cao, Wan-Li Ge, Ling-Dong Meng, Qun Chen, Yi Miao, Kui-Rong Jiang, Jing-Jing Zhang
Article Number: 457
Published online on: 02 November 2022

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Article Open Access

lncRNA EGFEM1P promotes thyroid cancer progression by acting as an miR‑369‑3p sponge and upregulating TCF4

Shijie Yi, Longqing Liu, Zhiwei Chen
Article Number: 456
Published online on: 01 November 2022

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Review Open Access

Insight into the physiological and pathological roles of USP44, a potential tumor target (Review)

Yuming Lou, Minfeng Ye, Chaoyang Xu, Feng Tao
Article Number: 455
Published online on: 01 November 2022

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Article Open Access

Morbidity and mortality among patients with breast cancer receiving anticancer treatment before and during the COVID‑19 pandemic: A single tertiary center experience

Marwan Al-Hajeili, Reem Ujaimi, Omar Iskanderani, Nora Trabulsi, Somayah Bawazeer
Article Number: 454
Published online on: 01 November 2022

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Review Open Access

Clinical characteristics and prognosis of gastrointestinal stromal tumors with rare site metastasis (Review)

Xinhui Yu, Xiaoxiang Liang, Kunming Wen
Article Number: 453
Published online on: 01 November 2022

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Case Report Open Access

Spindle cell sarcoma with KIAA1549‑BRAF resembling infantile fibrosarcoma morphologically: A case report and literature review

Tomoko Fujikawa, Suguru Uemura, Makiko Yoshida, Sayaka Hyodo, Aiko Kozaki, Atsuro Saito, Kenji Kishimoto, Toshiaki Ishida, Takeshi Mori, Ayano Uematsu, Keiichi Morita, Tadashi Hatakeyama, Akihiro Tamura, Nobuyuki Yamamoto, Masato Komatsu, Toshinori Soejima, Daiichiro Hasegawa, Yoshiyuki Kosaka
Article Number: 452
Published online on: 01 November 2022

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Case Report Open Access

Primary malignant melanoma of the bladder collides with high‑grade non‑invasive urothelial papillary carcinoma:
A case report

Xiaodan Chen, Haiyan Ge, Junjie Yang, Bin Huang, Hongsheng Liu
Article Number: 451
Published online on: 31 October 2022

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Article Open Access

Head and neck squamous cancer cells enhance the differentiation of human mesenchymal stem cells to adipogenic and osteogenic linages in vitro

Till Jasper Meyer, Stephan Hackenberg, Marietta Herrmann, Thomas Gehrke, Magdalena Steber, Rudolf Hagen, Norbert Kleinsasser, Agmal Scherzad
Article Number: 450
Published online on: 31 October 2022

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Case Report

A huge retroperitoneal ganglioneuroma in a middle‑aged patient: Report of a diagnostically challenging case with review of the literature

Rawa Bapir, Tahir A. Hawrami, Ismaeel Aghaways, Rawa M. Ali, Dilan S. Hiwa, Dlsoz M. Hussein, Fahmi H. Kakamad, Abdulwahid M. Salih
Article Number: 449
Published online on: 31 October 2022

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Article Open Access

Ursodeoxycholic acid inhibits epithelial‑mesenchymal transition, suppressing invasiveness of bile duct cancer cells: An in vitro study

Jin Lee, Eun Mi Hong, Jung Han Kim, Jung Hee Kim, Jang Han Jung, Se Woo Park, Dong Hee Koh
Article Number: 448
Published online on: 26 October 2022

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Article Open Access

Establishment of gastric cancer organoid and its application in individualized therapy

Xin Miao, Caiming Wang, Changpeng Chai, Huan Tang, Jinjing Hu, Zhenjie Zhao, Wei Luo, Hui Zhang, Kexiang Zhu, Wence Zhou, Hao Xu
Article Number: 447
Published online on: 26 October 2022

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Article Open Access

Clinical‑radiomic model in advanced kidney cancer predicts response to tyrosine kinase inhibitors

Adrián A. Negreros-Osuna, Diego A. Ramírez‑Mendoza, Claudio Casas-Murillo, Abraham Guerra‑Cepeda, David Hernández‑Barajas, Guillermo Elizondo-Riojas
Article Number: 446
Published online on: 26 October 2022

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Article Open Access

Pan‑cancer analysis supports MAPK12 as a potential prognostic and immunotherapeutic target in multiple tumor types, including in THCA

Jinju Wang, Zhe Song, Li Ren, Bowei Zhang, Yun Zhang, Xianwei Yang, Tong Liu, Yi Gu, Chao Feng
Article Number: 445
Published online on: 26 October 2022

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Article Open Access

Expression level comparison of marker genes related to early embryonic development and tumor growth

Qiu-Chen Cai, Da-Lun Li, Ying Zhang, Yun-Yi Liu, Pei Fang, Si-Qin Zheng, Yue-Yan Zhang, Ya-Kun Yang, Chun Hou, Cheng-Wei Gao, Qi-Shun Zhu, Chuan-Hai Cao
Article Number: 444
Published online on: 26 October 2022

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Case Report Open Access

Ovarian collision tumor consisting of sclerosing stromal tumor and mature cystic teratoma complicated with Meigs syndrome: A case report

Jiaren Zhang, Lian He, Li Yang, Ji Wang, Ling Wei, Xuejing Ma, Lin Jiang
Article Number: 443
Published online on: 26 October 2022

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Article Open Access

Gene panel testing detects important genetic alterations in ulcerative colitis‑associated colorectal neoplasia

Yoshifumi Shimada, Mae Nakano, Ken-Ichi Mizuno, Junji Yokoyama, Akio Matsumoto, Kana Tanaka, Hidehito Oyanagi, Masato Nakano, Yuki Hirose, Hiroshi Ichikawa, Jun Sakata, Hitoshi Kameyama, Yasumasa Takii, Mika Sugai, Yiwei Ling, Shiho Takeuchi, Shujiro Okuda, Shuji Terai, Yoichi Ajioka, Toshifumi Wakai
Article Number: 442
Published online on: 25 October 2022

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Article Open Access

Cyclin B1 expression as an independent prognostic factor for lung adenocarcinoma and its potential pathways

Yi Li, Yuanxiu Leng, Yudi Dong, Yongxiang Song, Qiaoyuan Wu, Ni Jiang, Hui Dong, Fang Chen, Qing Luo, Chen Cheng
Article Number: 441
Published online on: 25 October 2022

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Case Report Open Access

Usefulness of malignant pleural effusion for early cytological diagnosis of mesothelioma in situ: A case report

Yuki Yabuuchi, Kenzo Hiroshima, Hisayuki Oshima, Jun Kanazawa, Kenji Hayashihara, Takayuki Nakagawa, Masaki Shimanouchi, Shingo Usui, Shuji Oh‑ishi, Takefumi Saito, Nobuyuki Hizawa, Yuko Minami
Article Number: 440
Published online on: 25 October 2022

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Article Open Access

NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma

Xiao-Wen Zhang, Lu-Yi Wu, Hui-Rong Liu, Yan Huang, Qin Qi, Rui Zhong, Lu Zhu, Chun-Fang Gao, Lin Zhou, Jian Yu, Huan-Gan Wu
Article Number: 439
Published online on: 21 October 2022

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Article Open Access

LINC01635, a long non‑coding RNA with a cancer/testis expression pattern, promotes lung cancer progression by sponging miR‑455‑5p

Wenyi Shen, Juan Pu, Shanye Gu, Jing Sun, Lili Wang, Bin Tan, Jianmeng Chen, Yangsong Zuo
Article Number: 438
Published online on: 21 October 2022

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Article Open Access

Comparison of overall survival after neoadjuvant and adjuvant chemotherapy in patients with early breast cancer with immediate breast reconstruction after mastectomy: A retrospective, matched case‑control study

Chia-Hua Liu, Jie-Ru Yang, I-Chen Tsai, Chiann-Yi Hsu, Lum Chih Yean, Chih-Chiang Hung
Article Number: 437
Published online on: 21 October 2022

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Article Open Access

Tumor expression of CXCL12 and survival of patients with colorectal cancer: A meta‑analysis

Shuqi Zhang, Guoxiong Li
Article Number: 436
Published online on: 21 October 2022

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Article Open Access

Systematic analysis of expression profiles and prognostic significance of the FGF gene family in pancreatic adenocarcinoma

Yu-Xin Chen, Xiao-Juan Liu, Ling Yang, Jia-Jing He, Yong-Mei Jiang, Jia Mai
Article Number: 435
Published online on: 19 October 2022

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Article Open Access

Survival outcomes in patients with T3‑4aN0M0 glottic laryngeal squamous cell carcinoma and evaluation of postoperative radiotherapy Corrigendum in /10.3892/ol.2024.14456

Jian Zhou, Yu Heng, Yue Yang, Xiaoke Zhu, Liang Zhou, Hongli Gong, Chengzhi Xu, Lei Tao
Article Number: 434
Published online on: 19 October 2022

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Article Open Access

Strong prognostic value of SLAMF7 protein expression in patients with lymph node‑positive breast cancer

Mourad Assidi
Article Number: 433
Published online on: 19 October 2022

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Article Open Access

Low serum albumin levels and high neutrophil counts are predictive of a poorer prognosis in patients with metastatic breast cancer

Mengqi Xiang, Huachuan Zhang, Jinjun Tian, Yihang Yuan, Zhihua Xu, Jing Chen
Article Number: 432
Published online on: 19 October 2022

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Article Open Access

Complete response of recurrent oral squamous cell carcinoma treated with cetuximab in combination with radiotherapy: A case series

Tomofumi Naruse, Kohei Furukawa, Taro Miyoshi, Kota Morishita, Mitsunobu Otsuru, Masahiro Umeda
Article Number: 431
Published online on: 19 October 2022

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Case Report

Primary vaginal malignant melanoma successfully treated with combination therapy: A case report

Ping Yin, Xiaolin Ma, Yanfei Zhang, Yang Song, Yuntao Wang, Zhong Lu
Article Number: 430
Published online on: 19 October 2022

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Case Report Open Access

Robotic complete mesocolic excision of right‑sided colon cancer with bulky lymph node metastases using the da Vinci® Si™ system: A case report

Shiki Fujino, Katsuki Danno, Takashi Takeda, Shuhei Murao, Kei Yamamoto, Masaya Higashiguchi, Kozo Noguchi, Takafumi Hirao, Yoshio Oka
Article Number: 429
Published online on: 19 October 2022

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Article

Cerebrospinal fluid neurofilament light chain as a potential prognostic biomarker for leptomeningeal metastasis

Jae-Won Hyun, Yeseul Kim, Ki Hoon Kim, Su-Hyun Kim, Eun Young Park, Ji-Hye Youn, Heon Yoo, Ho-Shin Gwak, Ho Jin Kim
Article Number: 428
Published online on: 19 October 2022

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Article Open Access

Aberrant expression of polo‑like kinase 4 in renal cell carcinoma: Association with clinicopathological characteristics and long‑term survival

Wenxia Jiang, Yan Zhao, Suxia Zhang, Yu Zeng, Jun Ma
Article Number: 427
Published online on: 14 October 2022

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Article Open Access

miR-20b-5p is a novel biomarker for detecting prostate cancer

Tian-Yuan Zhai, Meng Dou, Yu-Bo Ma, Hong Wang, Fang Liu, Lian-Dong Zhang, Tie Chong, Zi-Ming Wang, Li Xue
Article Number: 426
Published online on: 12 October 2022

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Article Open Access

Meta‑analysis of the efficacy and safety of sintilimab for treating advanced non‑small cell lung cancer

Jiejie Xie, Xueyan Wu, Jianmei Wu, Fang Huang, Luning Xu
Article Number: 425
Published online on: 12 October 2022

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Article Open Access

DNA methylation at hepatitis B virus integrants and flanking host mitochondrially encoded cytochrome C oxidase III

Ritsuko Oikawa, Yoshiyuki Watanabe, Hiroshi Yotsuyanagi, Hiroyuki Yamamoto, Fumio Itoh
Article Number: 424
Published online on: 11 October 2022

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Article

Low expression of MYCN promotes cisplatin resistance by suppressing cisplatin‑induced apoptosis in epithelial ovarian cancer

Rao Yu, Hao Zhang, Rong Wang, Lin Xiao
Article Number: 423
Published online on: 11 October 2022

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Article Open Access

BANCR positively regulates the HIF‑1α/VEGF‑C/VEGFR‑3 pathway in a hypoxic microenvironment to promote lymphangiogenesis in pancreatic cancer cells

Shaolong Hao, Wei Han, Yu Ji, Hao Sun, Haowei Shi, Jihong Ma, James Yip, Yuchuan Ding
Article Number: 422
Published online on: 11 October 2022

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Article Open Access

Anti‑tumor effects of perampanel in malignant glioma cells

Juri Tatsuoka, Emiko Sano, Yuya Hanashima, Chihiro Yagi, Shun Yamamuro, Koichiro Sumi, Hiroyuki Hara, Kazuhide Takada, Kazunori Kanemaru, Shihoko Komine‑Aizawa, Yoichi Katayama, Atsuo Yoshino
Article Number: 421
Published online on: 07 October 2022

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Article Open Access

Ki67 testing in the clinical management of patients with non‑metastatic colorectal cancer: Detecting the optimal cut‑off value based on the Restricted Cubic Spline model

Hong Tao Lei, Shan Yan, Yin Hua He, Ning Xu, Min Zhao, Chun Jiao Yu, Hong Lin Li, Sai Kuang, Zhan Hang Cui, Jing Fang
Article Number: 420
Published online on: 07 October 2022

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Review Open Access

FLASH radiotherapy: A promising new method for radiotherapy (Review)

Yinghao Lv, Yue Lv, Zhen Wang, Tian Lan, Xuping Feng, Hao Chen, Jiang Zhu, Xiao Ma, Jinpeng Du, Guimin Hou, Wenwei Liao, Kefei Yuan, Hong Wu
Article Number: 419
Published online on: 05 October 2022

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Article Open Access

Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Review
Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Article Open Access

Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Article Open Access

Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Article Open Access

Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Article Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Article Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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