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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2022 Volume 24 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Bleomycin‑based electrochemotherapy for the treatment of a Buschke‑Löwenstein tumor (perianal giant condyloma) in an HIV‑positive kidney transplant recipient: A case report

Francesco Russano, Irene Russo, Paolo Del Fiore, Claudia Di Prata, Simone Mocellin, Mauro Alaibac
Article Number: 466
Published online on: 07 November 2022

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Review Open Access

Cancer stem cells markers in ovarian cancer: Clinical and therapeutic significance (Review)

Patrycja Królewska-Daszczyńska, Dominika Wendlocha, Marta Smycz-Kubańska, Sebastian Stępień, Aleksandra Mielczarek-Palacz
Article Number: 465
Published online on: 07 November 2022

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Case Report Open Access

EBV‑positive large‑cell and small‑cell neuroendocrine carcinoma of the nasopharynx: A case report and review of the literature

Zhen Su, Hao Wen Yan, Guo Rong Zou
Article Number: 464
Published online on: 07 November 2022

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Article Open Access

Biomarkers for anti‑vascular endothelial growth factor drugs

Sho Kuriyama, Takeshi Yamada, Akihisa Matsuda, Goro Takahashi, Takuma Iwai, Kohki Takeda, Koji Ueda, Toshimitsu Miyasaka, Yasuyuki Yokoyama, Seiichi Shinji, Hiromichi Sonoda, Ryo Ohta, Kazuhide Yonaga, Shintaro Kanaka, Hiroshi Yoshida
Article Number: 463
Published online on: 07 November 2022

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Article Open Access

Heat shock protein 20 suppresses breast carcinogenesis by inhibiting the MAPK and AKT signaling pathways

Yinxi Yang, Yifeng Wu, Lihong Hou, Xin Ge, Guoquan Song, Hongdou Jin
Article Number: 462
Published online on: 03 November 2022

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Review Open Access

FOXK2 transcription factor and its roles in tumorigenesis (Review)

Zhaojun Wang, Xinling Liu, Zhanju Wang, Zhenbo Hu
Article Number: 461
Published online on: 03 November 2022

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Article Open Access

Potential of blood exosomal ENAH, SEPT9, EGF, MMP‑9 and CXCL8 for the early screening of breast cancer

Zijing Zhang, Hongying Wang, Yiting Jin, Chengyu Chu, Jinsong Bai, Juntian Huang, Lemei Yang, Feng Tang, Liping Zou, Shuyang Wang, Qiang Zou
Article Number: 460
Published online on: 03 November 2022

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Case Report Open Access

Synchronous mantle cell lymphoma bone marrow involvement complicated with extensive‑stage small cell lung cancer: A case report and literature review

Nengwen Xu, Zhimin Fan, Weie Liu, Cangjian Zhang, Junyu Zhang, Linjie Li
Article Number: 459
Published online on: 02 November 2022

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Case Report Open Access

Near complete remission of a locally advanced giant melanoma of the vulva following hypo‑fractionated radiotherapy and immune checkpoint inhibitors: A case report

Shuang Chen, Xuemei Deng, Chen Xie, Qingke Dong, Hongru Yang
Article Number: 458
Published online on: 02 November 2022

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Article Open Access

Suppressive effect of YY1‑mediated RGS22 regulation on the proliferation, migration and invasion of pancreatic ductal adenocarcinoma

Shou-Ji Cao, Wan-Li Ge, Ling-Dong Meng, Qun Chen, Yi Miao, Kui-Rong Jiang, Jing-Jing Zhang
Article Number: 457
Published online on: 02 November 2022

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Article Open Access

lncRNA EGFEM1P promotes thyroid cancer progression by acting as an miR‑369‑3p sponge and upregulating TCF4

Shijie Yi, Longqing Liu, Zhiwei Chen
Article Number: 456
Published online on: 01 November 2022

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Review Open Access

Insight into the physiological and pathological roles of USP44, a potential tumor target (Review)

Yuming Lou, Minfeng Ye, Chaoyang Xu, Feng Tao
Article Number: 455
Published online on: 01 November 2022

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Article Open Access

Morbidity and mortality among patients with breast cancer receiving anticancer treatment before and during the COVID‑19 pandemic: A single tertiary center experience

Marwan Al-Hajeili, Reem Ujaimi, Omar Iskanderani, Nora Trabulsi, Somayah Bawazeer
Article Number: 454
Published online on: 01 November 2022

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Review Open Access

Clinical characteristics and prognosis of gastrointestinal stromal tumors with rare site metastasis (Review)

Xinhui Yu, Xiaoxiang Liang, Kunming Wen
Article Number: 453
Published online on: 01 November 2022

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Case Report Open Access

Spindle cell sarcoma with KIAA1549‑BRAF resembling infantile fibrosarcoma morphologically: A case report and literature review

Tomoko Fujikawa, Suguru Uemura, Makiko Yoshida, Sayaka Hyodo, Aiko Kozaki, Atsuro Saito, Kenji Kishimoto, Toshiaki Ishida, Takeshi Mori, Ayano Uematsu, Keiichi Morita, Tadashi Hatakeyama, Akihiro Tamura, Nobuyuki Yamamoto, Masato Komatsu, Toshinori Soejima, Daiichiro Hasegawa, Yoshiyuki Kosaka
Article Number: 452
Published online on: 01 November 2022

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Case Report Open Access

Primary malignant melanoma of the bladder collides with high‑grade non‑invasive urothelial papillary carcinoma:
A case report

Xiaodan Chen, Haiyan Ge, Junjie Yang, Bin Huang, Hongsheng Liu
Article Number: 451
Published online on: 31 October 2022

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Article Open Access

Head and neck squamous cancer cells enhance the differentiation of human mesenchymal stem cells to adipogenic and osteogenic linages in vitro

Till Jasper Meyer, Stephan Hackenberg, Marietta Herrmann, Thomas Gehrke, Magdalena Steber, Rudolf Hagen, Norbert Kleinsasser, Agmal Scherzad
Article Number: 450
Published online on: 31 October 2022

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Case Report

A huge retroperitoneal ganglioneuroma in a middle‑aged patient: Report of a diagnostically challenging case with review of the literature

Rawa Bapir, Tahir A. Hawrami, Ismaeel Aghaways, Rawa M. Ali, Dilan S. Hiwa, Dlsoz M. Hussein, Fahmi H. Kakamad, Abdulwahid M. Salih
Article Number: 449
Published online on: 31 October 2022

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Article Open Access

Ursodeoxycholic acid inhibits epithelial‑mesenchymal transition, suppressing invasiveness of bile duct cancer cells: An in vitro study

Jin Lee, Eun Mi Hong, Jung Han Kim, Jung Hee Kim, Jang Han Jung, Se Woo Park, Dong Hee Koh
Article Number: 448
Published online on: 26 October 2022

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Article Open Access

Establishment of gastric cancer organoid and its application in individualized therapy

Xin Miao, Caiming Wang, Changpeng Chai, Huan Tang, Jinjing Hu, Zhenjie Zhao, Wei Luo, Hui Zhang, Kexiang Zhu, Wence Zhou, Hao Xu
Article Number: 447
Published online on: 26 October 2022

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Article Open Access

Clinical‑radiomic model in advanced kidney cancer predicts response to tyrosine kinase inhibitors

Adrián A. Negreros-Osuna, Diego A. Ramírez‑Mendoza, Claudio Casas-Murillo, Abraham Guerra‑Cepeda, David Hernández‑Barajas, Guillermo Elizondo-Riojas
Article Number: 446
Published online on: 26 October 2022

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Article Open Access

Pan‑cancer analysis supports MAPK12 as a potential prognostic and immunotherapeutic target in multiple tumor types, including in THCA

Jinju Wang, Zhe Song, Li Ren, Bowei Zhang, Yun Zhang, Xianwei Yang, Tong Liu, Yi Gu, Chao Feng
Article Number: 445
Published online on: 26 October 2022

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Article Open Access

Expression level comparison of marker genes related to early embryonic development and tumor growth

Qiu-Chen Cai, Da-Lun Li, Ying Zhang, Yun-Yi Liu, Pei Fang, Si-Qin Zheng, Yue-Yan Zhang, Ya-Kun Yang, Chun Hou, Cheng-Wei Gao, Qi-Shun Zhu, Chuan-Hai Cao
Article Number: 444
Published online on: 26 October 2022

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Case Report Open Access

Ovarian collision tumor consisting of sclerosing stromal tumor and mature cystic teratoma complicated with Meigs syndrome: A case report

Jiaren Zhang, Lian He, Li Yang, Ji Wang, Ling Wei, Xuejing Ma, Lin Jiang
Article Number: 443
Published online on: 26 October 2022

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Article Open Access

Gene panel testing detects important genetic alterations in ulcerative colitis‑associated colorectal neoplasia

Yoshifumi Shimada, Mae Nakano, Ken-Ichi Mizuno, Junji Yokoyama, Akio Matsumoto, Kana Tanaka, Hidehito Oyanagi, Masato Nakano, Yuki Hirose, Hiroshi Ichikawa, Jun Sakata, Hitoshi Kameyama, Yasumasa Takii, Mika Sugai, Yiwei Ling, Shiho Takeuchi, Shujiro Okuda, Shuji Terai, Yoichi Ajioka, Toshifumi Wakai
Article Number: 442
Published online on: 25 October 2022

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Article Open Access

Cyclin B1 expression as an independent prognostic factor for lung adenocarcinoma and its potential pathways

Yi Li, Yuanxiu Leng, Yudi Dong, Yongxiang Song, Qiaoyuan Wu, Ni Jiang, Hui Dong, Fang Chen, Qing Luo, Chen Cheng
Article Number: 441
Published online on: 25 October 2022

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Case Report Open Access

Usefulness of malignant pleural effusion for early cytological diagnosis of mesothelioma in situ: A case report

Yuki Yabuuchi, Kenzo Hiroshima, Hisayuki Oshima, Jun Kanazawa, Kenji Hayashihara, Takayuki Nakagawa, Masaki Shimanouchi, Shingo Usui, Shuji Oh‑ishi, Takefumi Saito, Nobuyuki Hizawa, Yuko Minami
Article Number: 440
Published online on: 25 October 2022

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Article Open Access

NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma

Xiao-Wen Zhang, Lu-Yi Wu, Hui-Rong Liu, Yan Huang, Qin Qi, Rui Zhong, Lu Zhu, Chun-Fang Gao, Lin Zhou, Jian Yu, Huan-Gan Wu
Article Number: 439
Published online on: 21 October 2022

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Article Open Access

LINC01635, a long non‑coding RNA with a cancer/testis expression pattern, promotes lung cancer progression by sponging miR‑455‑5p

Wenyi Shen, Juan Pu, Shanye Gu, Jing Sun, Lili Wang, Bin Tan, Jianmeng Chen, Yangsong Zuo
Article Number: 438
Published online on: 21 October 2022

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Article Open Access

Comparison of overall survival after neoadjuvant and adjuvant chemotherapy in patients with early breast cancer with immediate breast reconstruction after mastectomy: A retrospective, matched case‑control study

Chia-Hua Liu, Jie-Ru Yang, I-Chen Tsai, Chiann-Yi Hsu, Lum Chih Yean, Chih-Chiang Hung
Article Number: 437
Published online on: 21 October 2022

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Article Open Access

Tumor expression of CXCL12 and survival of patients with colorectal cancer: A meta‑analysis

Shuqi Zhang, Guoxiong Li
Article Number: 436
Published online on: 21 October 2022

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Article Open Access

Systematic analysis of expression profiles and prognostic significance of the FGF gene family in pancreatic adenocarcinoma

Yu-Xin Chen, Xiao-Juan Liu, Ling Yang, Jia-Jing He, Yong-Mei Jiang, Jia Mai
Article Number: 435
Published online on: 19 October 2022

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Article Open Access

Survival outcomes in patients with T3‑4aN0M0 glottic laryngeal squamous cell carcinoma and evaluation of postoperative radiotherapy Corrigendum in /10.3892/ol.2024.14456

Jian Zhou, Yu Heng, Yue Yang, Xiaoke Zhu, Liang Zhou, Hongli Gong, Chengzhi Xu, Lei Tao
Article Number: 434
Published online on: 19 October 2022

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Article Open Access

Strong prognostic value of SLAMF7 protein expression in patients with lymph node‑positive breast cancer

Mourad Assidi
Article Number: 433
Published online on: 19 October 2022

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Article Open Access

Low serum albumin levels and high neutrophil counts are predictive of a poorer prognosis in patients with metastatic breast cancer

Mengqi Xiang, Huachuan Zhang, Jinjun Tian, Yihang Yuan, Zhihua Xu, Jing Chen
Article Number: 432
Published online on: 19 October 2022

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Article Open Access

Complete response of recurrent oral squamous cell carcinoma treated with cetuximab in combination with radiotherapy: A case series

Tomofumi Naruse, Kohei Furukawa, Taro Miyoshi, Kota Morishita, Mitsunobu Otsuru, Masahiro Umeda
Article Number: 431
Published online on: 19 October 2022

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Case Report

Primary vaginal malignant melanoma successfully treated with combination therapy: A case report

Ping Yin, Xiaolin Ma, Yanfei Zhang, Yang Song, Yuntao Wang, Zhong Lu
Article Number: 430
Published online on: 19 October 2022

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Case Report Open Access

Robotic complete mesocolic excision of right‑sided colon cancer with bulky lymph node metastases using the da Vinci® Si™ system: A case report

Shiki Fujino, Katsuki Danno, Takashi Takeda, Shuhei Murao, Kei Yamamoto, Masaya Higashiguchi, Kozo Noguchi, Takafumi Hirao, Yoshio Oka
Article Number: 429
Published online on: 19 October 2022

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Article

Cerebrospinal fluid neurofilament light chain as a potential prognostic biomarker for leptomeningeal metastasis

Jae-Won Hyun, Yeseul Kim, Ki Hoon Kim, Su-Hyun Kim, Eun Young Park, Ji-Hye Youn, Heon Yoo, Ho-Shin Gwak, Ho Jin Kim
Article Number: 428
Published online on: 19 October 2022

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Article Open Access

Aberrant expression of polo‑like kinase 4 in renal cell carcinoma: Association with clinicopathological characteristics and long‑term survival

Wenxia Jiang, Yan Zhao, Suxia Zhang, Yu Zeng, Jun Ma
Article Number: 427
Published online on: 14 October 2022

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Article Open Access

miR-20b-5p is a novel biomarker for detecting prostate cancer

Tian-Yuan Zhai, Meng Dou, Yu-Bo Ma, Hong Wang, Fang Liu, Lian-Dong Zhang, Tie Chong, Zi-Ming Wang, Li Xue
Article Number: 426
Published online on: 12 October 2022

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Article Open Access

Meta‑analysis of the efficacy and safety of sintilimab for treating advanced non‑small cell lung cancer

Jiejie Xie, Xueyan Wu, Jianmei Wu, Fang Huang, Luning Xu
Article Number: 425
Published online on: 12 October 2022

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Article Open Access

DNA methylation at hepatitis B virus integrants and flanking host mitochondrially encoded cytochrome C oxidase III

Ritsuko Oikawa, Yoshiyuki Watanabe, Hiroshi Yotsuyanagi, Hiroyuki Yamamoto, Fumio Itoh
Article Number: 424
Published online on: 11 October 2022

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Article

Low expression of MYCN promotes cisplatin resistance by suppressing cisplatin‑induced apoptosis in epithelial ovarian cancer

Rao Yu, Hao Zhang, Rong Wang, Lin Xiao
Article Number: 423
Published online on: 11 October 2022

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Article Open Access

BANCR positively regulates the HIF‑1α/VEGF‑C/VEGFR‑3 pathway in a hypoxic microenvironment to promote lymphangiogenesis in pancreatic cancer cells

Shaolong Hao, Wei Han, Yu Ji, Hao Sun, Haowei Shi, Jihong Ma, James Yip, Yuchuan Ding
Article Number: 422
Published online on: 11 October 2022

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Article Open Access

Anti‑tumor effects of perampanel in malignant glioma cells

Juri Tatsuoka, Emiko Sano, Yuya Hanashima, Chihiro Yagi, Shun Yamamuro, Koichiro Sumi, Hiroyuki Hara, Kazuhide Takada, Kazunori Kanemaru, Shihoko Komine‑Aizawa, Yoichi Katayama, Atsuo Yoshino
Article Number: 421
Published online on: 07 October 2022

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Article Open Access

Ki67 testing in the clinical management of patients with non‑metastatic colorectal cancer: Detecting the optimal cut‑off value based on the Restricted Cubic Spline model

Hong Tao Lei, Shan Yan, Yin Hua He, Ning Xu, Min Zhao, Chun Jiao Yu, Hong Lin Li, Sai Kuang, Zhan Hang Cui, Jing Fang
Article Number: 420
Published online on: 07 October 2022

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Review Open Access

FLASH radiotherapy: A promising new method for radiotherapy (Review)

Yinghao Lv, Yue Lv, Zhen Wang, Tian Lan, Xuping Feng, Hao Chen, Jiang Zhu, Xiao Ma, Jinpeng Du, Guimin Hou, Wenwei Liao, Kefei Yuan, Hong Wu
Article Number: 419
Published online on: 05 October 2022

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Journal Cover
November-2026 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Ivonescimab combined with radiotherapy in the treatment of advanced lung adenocarcinoma with high expression of PD‑L1: A case report

Qi Zhou, Bo Yang, Hongyi Cai, Jun Jiang, Rong Chen
Article Number: 538
Published online on: 02 October 2026

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Article Open Access

Association between antidepressant exposure and prognosis in breast cancer: A systematic review and meta‑analysis

Qisong Chen, Yihan Shen, Xiaoming Zhang, Ting Jiang, Shiyan Zhang, Xinyan Yu, Feng Hong
Article Number: 537
Published online on: 02 October 2026

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Review Open Access

Brain‑derived neurotrophic factor in solid tumor angiogenesis and neurovascular‑immune interactions (Review)

Guoqing Zhu, Dianliang Zhang, Hao Wang, Sen Yan, Mingchao Ni, Shangkun Ning, Chong Wang, Mei Liu, Jibing Liu
Article Number: 536
Published online on: 01 October 2026

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Article Open Access

hnRNPC promotes oral squamous cell carcinoma progression via N6‑methyladenosine‑dependent stabilization of BCAT1 to enhance branched‑chain amino acid metabolism

Zhixin Zhang, Xin Gao, Ting Han, Fei Chai, Menghui Gao, Yulin An
Article Number: 535
Published online on: 01 October 2026

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Expression of Concern Open Access

[Expression of Concern] Reduced migration of Ishikawa cells associated with downregulation of aquaporin‑5

Xiu Xiu Jiang, Kai Hong Xu, Jun Yan Ma, Yong Hong Tian, Xiao Yan Guo, Jun Lin, Rui Jin Wu
Article Number: 534
Published online on: 30 September 2026

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Case Report Open Access

A thoracic SMARCA4‑deficient undifferentiated tumor: A case report

Xiaocheng Wang, Miao Chen, Mingzhe Wang, Chengjun Ban, Lishan Zhang, Heng Zou, Hongwu Wang, Bing Yang
Article Number: 533
Published online on: 29 September 2026

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Case Report Open Access

Stage IIIB pulmonary sarcomatoid carcinoma treated with spatially fractionated radiotherapy combined with antiangiogenic therapy and sequential chemo‑immunotherapy: A case report

Zijian Qiu, Feng Xuan, Xi Mao, Peipei Yang, Xiaoping Zhu
Article Number: 532
Published online on: 29 September 2026

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Article Open Access

Single‑cell transcriptomics identifies PRDX1 and GPX4 as potential ferroptosis regulators and tumor microenvironment‑­related molecules in hepatocellular carcinoma

Zhou Zhang, Hui Chen, Chen Qian, Ningning Yang, Zijing Liu, Ruirui Yang
Article Number: 531
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] Interferon‑α suppresses invasion and enhances cisplatin‑mediated apoptosis and autophagy in human osteosarcoma cells

Jun Zhao, Mingli Wang, Zeng Li, Jingxian Chen, Zongshen Yin, Jun Chang, Dongmei Gao, Shiping Wang
Article Number: 530
Published online on: 28 September 2026

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Article Open Access

KRT14 activated by transcription factor E2F1 promotes bladder cancer progression

Xingheng Chen, Sinan Liu, Xiaosong Zhang, Xiang Chen, Chenlu Wang
Article Number: 529
Published online on: 24 September 2026

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Review Open Access

Research progress of pancreatic cancer based on ferroptosis‑cuproptosis interaction (Review)

Wenqing Liu, Minglu Ding, Ruijiao Ji, Zhenmin Qiao, Ran Liu, Peijian Chen, Lantao Liu
Article Number: 528
Published online on: 24 September 2026

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Correction Open Access

[Corrigendum] Decreased expression of CD63 tetraspanin protein predicts elevated malignant potential in human esophageal cancer

Xiaojing Lai, Qing Gu, Xia Zhou, Wei Feng, Xiao Lin, Yan He, Jinming Cao, Pengfei Liu, Huojun Zhang, Xiao Zheng
Article Number: 527
Published online on: 24 September 2026

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Case Report Open Access

Therapy‑related acute myeloid leukemia with a rare complex karyotype following first‑line therapy for small cell lung cancer: A case report

Lin Luo, Sha Yu
Article Number: 526
Published online on: 23 September 2026

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Article Open Access

Netupitant‑palonosetron combined with dexamethasone for preventing chemotherapy‑induced nausea and vomiting in high‑risk patients with colorectal cancer receiving moderately emetogenic chemotherapy: A retrospective study

Jiwen Fan, Wenjuan Lai, Boran Cheng, Meijing Chen, Jing Gao, Shubin Wang, Gangling Tong
Article Number: 525
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] Upregulation of H19 promotes invasion and induces epithelial‑to‑mesenchymal transition in esophageal cancer

Cheng Huang, Lihua Cao, Limin Qiu, Xiaoli Dai, Linwei Ma, Yingting Zhou, Huifen Li, Min Gao, Weiyong Li, Qing Zhang, Koulan Han, Hongzhen Lv
Article Number: 524
Published online on: 23 September 2026

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Article Open Access

Pan‑cancer prognostic value of TGFBR1: Bioinformatics and experimental validation with a focus on gastric cancer

Xia Zhao, Lufan Shen, Zhiyuan Gong, Mengwen Lv, Yan Zhang, Bingxi Tang, Xinli Li
Article Number: 523
Published online on: 21 September 2026

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Article Open Access

MAD2L1 overexpression promotes breast cancer progression and confers resistance to paclitaxel via proteasomal stabilization

Shih-Ho Wang, Cheng-Hsi Yeh, Chia-Wei Wu, Chia-Yi Hsu, Eing-Mei Tsai, Chao-Ming Hung, Ming-Wei Lin, Tsung-Hua Hsieh
Article Number: 522
Published online on: 21 September 2026

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Article Open Access

Efficacy of circulating tumour DNA in guiding postoperative adjuvant chemotherapy for resectable colorectal cancer: A meta‑analysis based on cohort studies

Jiale Ruan, Wen Shi, Wenwen Shi, Xinyan Zhang, Yixia Chen, Xiaoling Feng, Jian Song
Article Number: 521
Published online on: 21 September 2026

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Article Open Access

Clinicopathological role of microRNA‑205, microRNA‑223 and microRNA‑590 in vulvar cancer

Edyta Leśniak, Emilia Stec-Martyna, Bartłomiej Tomasik, Hanna Romanowicz, Oliwia Maciejewska, Jan Bieńkiewicz, Andrzej Malinowski, Miłosz Wilczyński
Article Number: 520
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 519
Published online on: 21 September 2026

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Article Open Access

Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Case Report Open Access

Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Article Open Access

Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Article Open Access

Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Article Open Access

Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Article Open Access

Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Review Open Access

Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Article Open Access

Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Article Open Access

Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Article Open Access

Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Review Open Access

Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara-Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Article Open Access

Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Review Open Access

Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Article

Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Review Open Access

Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Article

Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum-Quiroz, Noemí García-Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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December-2026 Volume 32 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article

Five‑fraction stereotactic body radiotherapy for prostate cancer in octogenarians and nonagenarians: A single‑institution retrospective cohort study

Atsuto Katano, Hideomi Yamashita
Article Number: 562
Published online on: 22 October 2026

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Article Open Access

Identification of SLC7A5 and transferrin as key ferroptosis modulators in triple‑negative breast cancer

Ruidi Liu, Xiao Cui, Bingyu Guo, Yiting Liu, Feng Lin, Zhiqiang Fu, Bing Xie
Article Number: 561
Published online on: 22 October 2026

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Article Open Access

PEG10/TRIB3 axis is associated with malignant behavior and Notch‑related signaling in oral squamous cell carcinoma cells

Jing Zhang, Ying Liu
Article Number: 560
Published online on: 22 October 2026

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Article Open Access

Diagnostic performance of a combined TAP, TAM, CA125 and CA153 panel for stage I breast cancer in patients with unilateral nipple discharge

Yingli Men, Ruiting Feng, Beibei Ye, Yahui Hu, Ping Wang, Jizhi Zhao, Yang Zheng, Hui Wang, Yinsen Song, Cong Ding
Article Number: 559
Published online on: 22 October 2026

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Correction Open Access

[Corrigendum] Individualized therapy based on the combination of mini‑PDX and NGS for a patient with metastatic AFP‑producing and HER‑2 amplified gastric cancer

Xiaodan Zhu, Xiaoqing Xu, Baonan Zhang, Yun Dong, Shixia Gong, Tingjie Gong, Feifei Zhang, Chunhui Jin
Article Number: 558
Published online on: 21 October 2026

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Article Open Access

Calycosin synergistically promotes ferroptosis in cervical cancer cells by inducing epithelial‑mesenchymal transition

Lei Zhang, Qiuyi Shen, Jingyi Zhu, Ping Wang, Wanhong Wei, Jie Zhou
Article Number: 557
Published online on: 19 October 2026

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Correction Open Access

[Corrigendum] Androgen deprivation therapy has no effect on Pim‑1 expression in a mouse model of prostate cancer

Jiang Wang, Gang Li, Bo Li, Hualin Song, Zhiqun Shang, Ning Jiang, Yuanjie Niu
Article Number: 556
Published online on: 19 October 2026

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Article Open Access

An interpretable machine‑learning model to predict moderate‑to‑severe acute radiation esophagitis following regional nodal irradiation for breast cancer

Bin He, Zhongchun Qi, Hengdi Zhang, Linling Li, Hua Li, Xinyun Zou, Yu Tan, Ling Zhang, Fangyuan Kong
Article Number: 555
Published online on: 16 October 2026

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Article Open Access

Anti‑neoplastic effects of Chrysanthemum indicum extract on a human hypopharyngeal squamous cell carcinoma cell line 

Ching-Wen Liu, Li-Ching Chang, Ting-Ting Lai, Hsiao-Chi Lai
Article Number: 554
Published online on: 16 October 2026

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Article Open Access

KAZALD1 upregulation predicts poor prognosis in epithelial ovarian cancer: Clinical validation and immune correlates

Ruru Zhao, Ye Hu, Jia Wang, Jingjing Lu, Guiqiang Du
Article Number: 553
Published online on: 15 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic effect of jolkinolide B and the mechanism of activity in breast cancer MDA‑MB‑231 cells

Chao Sun, Hongxia Cui, Hongyan Yang, Xiaohui Du, Liling Yue, Jicheng Liu, Yu Lin
Article Number: 552
Published online on: 14 October 2026

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Article Open Access

Optimal timing of thoracic radiotherapy with osimertinib in unresectable EGFR‑mutant non‑small cell lung cancer

Mengting Lai, Yanhua Zhou, Weili Yi, Jian Huang, Zhili Chen, Xin Yin, Li Qin, Dongning Huang
Article Number: 551
Published online on: 13 October 2026

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Article Open Access

Unveiling a dual‑pathway prognostic model: Integrating T cell‑related and ubiquitination‑related genes in lung adenocarcinoma

Shuang Zeng, Huidi Gao, Hongying Liang, Degang Zhang
Article Number: 550
Published online on: 13 October 2026

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Article Open Access

Supplementary value of primary tumor volume for prognostic stratification in patients with T3‑4 nasopharyngeal carcinoma: A retrospective cohort study

Hui Huang, Yusong Lu, Yingjie Ouyang, Min Pan, Xinyu Tang, Hongrui He, Tingfeng Zhang, Qi Gong, Chunqiao Chen, Qiuqiu Chen
Article Number: 549
Published online on: 13 October 2026

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Article

Safety of concurrent immune checkpoint inhibitor therapy during postoperative radiotherapy for triple‑negative breast cancer: A preliminary retrospective analysis

Gai Liang, Qu Zhang, Mengting Yuan, Guojun Yao, Feng Yuan
Article Number: 548
Published online on: 13 October 2026

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Expression of Concern Open Access

[Expression of Concern] Expression of L1 protein correlates with cluster of differentiation 24 and integrin β1 expression in gastrointestinal stromal tumors

Yue Du, Aihong Zhang, Zhongmin Jiang, Guowei Huang, Wenli Lu, Hesheng Wang
Article Number: 547
Published online on: 12 October 2026

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Article Open Access

Bulk and single‑cell analysis of FAM72D reveals its prognostic and functional relevance in hepatocellular carcinoma

Cuihao Zhao, Quliyang Yin, Jianfeng Yu, Weiqi Duan, Yufeng Li, Qian Jian
Article Number: 546
Published online on: 12 October 2026

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Article Open Access

Serum metabolomic signatures associated with gastric signet‑ring cell carcinoma: A dual‑platform mass spectrometry study

Huiling Cao, Shuwei Guo, Jinchang Li, Yuying Bian, Jianjiang Shen, Jia Wang, Fei Meng, Wenlu Sun, Qingmin Sun, Wanjian Gu
Article Number: 545
Published online on: 09 October 2026

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Case Report Open Access

Drug‑eluting bead transarterial chemoembolization with immunotherapy and targeted therapy for advanced clear cell renal cell carcinoma: A case report

Yin Gao, Qiang Xu, Dongxu Kang, Longzhen Piao
Article Number: 544
Published online on: 08 October 2026

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Case Report Open Access

Unexpected favorable response of stage IV gastric adenocarcinoma to sintilimab combined with chemotherapy: A case report

Jian Han, Zhe Zhu, Liang Huang, Liang Zhuang, Lihong Zhang, Yixin Tong, Chao Zhang, Hanlin Mu, Huaping Xie
Article Number: 543
Published online on: 08 October 2026

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Correction Open Access

[Corrigendum] Overexpression of microRNA-96-5p inhibits autophagy and apoptosis and enhances the proliferation, migration and invasiveness of human breast cancer cells

Yawei Shi, Yang Zhao, Nan Shao, Runyi Ye, Yin Lin, Ning Zhang, Wen Li, Yunjian Zhang, Shenming Wang
Article Number: 542
Published online on: 08 October 2026

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Article Open Access

Potential of clinical staging for long‑term prognosis prediction in pathological stage III gastric cancer

Naosuke Nakamichi, Hiroyuki Inoue, Takeshi Kubota, Toshiyuki Kosuga, Keiji Nishibeppu, Kazuya Takabatake, Shutaro Sumiyoshi, Junichi Hamada, Kento Kurashima, Hidemasa Kubo, Jun Kiuchi, Taisuke Imamura, Kenji Nanishi, Hiroki Shimizu, Tomohiro Arita, Yusuke Yamamoto, Hirotaka Konishi, Ryo Morimura, Hitoshi Fujiwara, Toshiya Ochiai, Atsushi Shiozaki
Article Number: 541
Published online on: 07 October 2026

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Article Open Access

NOL11 is a novel prognostic biomarker associated with immune infiltration and tumor progression in hepatocellular carcinoma

Hong Xie, Shengnan Wang, Xiaoyan Sheng, Lei Ye
Article Number: 540
Published online on: 07 October 2026

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Correction Open Access

[Corrigendum] Emodin induces apoptosis of human breast cancer cells by modulating the expression of apoptosis‑related genes

Cong Zu, Mingdi Zhang, Hui Xue, Xiaopeng Cai, Lei Zhao, Anning He, Guangyuan Qin, Chunshu Yang, Xinyu Zheng
Article Number: 539
Published online on: 02 October 2026

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