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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2025 Volume 30 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Prognostic model for predicting recurrence‑free survival in hepatocellular carcinoma using integrated analysis of single‑cell RNA‑sequencing and bulk RNA‑sequencing

Wentao Yang, Wenwen Lai, Qian Hu, Jingsheng Ma, Hailang Liu, Zelong Li, Qigen Li, Xiaohui Guo, Lin Zhong
Article Number: 537
Published online on: 22 September 2025

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Article Open Access

Progress of MRI‑based radiomics and deep learning for predicting the prognosis of locally advanced rectal cancer (Review)

Yuting Shi, Qiuhan Huang, Jiali Lyu, Tianjie Dong, Jihong Sun
Article Number: 536
Published online on: 19 September 2025

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Article Open Access

Preoperative C‑reactive protein‑albumin‑lymphocyte index predicts survival outcomes in patients with stage I‑III colorectal cancer: A retrospective cohort study

Jinquan Li, Xiaosheng Hu, Shanzhong Zhang
Article Number: 535
Published online on: 18 September 2025

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Review Open Access

Molecular mechanisms and functions of guanylate‑binding protein 2 in inflammation and cancer (Review)

Zeyu Liu, Shijun Peng, Jia Ouyang
Article Number: 534
Published online on: 18 September 2025

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Article Open Access

Identification of key molecules in micropapillary progression of lung adenocarcinoma: A comprehensive gene expression analysis study using the spatial gene expression solution methodology

Mai Matsumura, Hideaki Mitsui, Tetsukan Woo, Takehisa Suzuki, Hiromasa Arai, Chihiro Koike, Toshiaki Kataoka, Daisuke Motooka, Kiyoharu Fukushima, Koji Okudela
Article Number: 533
Published online on: 18 September 2025

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Review Open Access

Discoidin domain receptor tyrosine kinase 2: A new perspective on microenvironment remodeling and targeted therapy of solid tumors (Review)

Tong Lu, Huiying Guo, Hang Gong, Yaohui Ma, Yonggang Tian, Dekui Zhang
Article Number: 532
Published online on: 18 September 2025

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Article Open Access

Role of long non‑coding RNA‑mRNA interactions in resveratrol‑mediated inhibition of ovarian cancer cell proliferation

Weihua Zhu, Jiahui Feng, Yuanting Zhang, Qianqian Zhou, Herong Huang, Yu Yang
Article Number: 531
Published online on: 18 September 2025

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Article Open Access

Anticancer effects of thymoquinone on prostate cancer cells and natural killer cell activity

Nouf A. Aldarmahi, Nesrin I. Tarbiah, Nuha A. Alkhattabi, Huda F. Alshaibi
Article Number: 530
Published online on: 18 September 2025

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Case Report Open Access

Breast mucoepidermoid carcinoma: A case report

Min Xie, Chao-Chan Chen, Xiang-Yu Su, Zeng-Xiang Xu
Article Number: 529
Published online on: 17 September 2025

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Article Open Access

ERK‑driven autophagy enhances synergy of eribulin and cisplatin in triple‑negative breast cancer

Hyemi Ko, Myungsun Lee, Eunyoung Cha, Jinsun Lee
Article Number: 528
Published online on: 17 September 2025

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Tumor‑associated microbiota: Multi‑cancer landscape, mechanistic insights and clinical translation (Review)

Jindi Yang, Yige Dong, Yi Chen, Hong Liang, Shengyu Rong, Zhe Liu, Qiulei Lang
Article Number: 527
Published online on: 16 September 2025

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The advantages and challenges of sorafenib combination therapy: Drug resistance, toxicity and future directions (Review)

Mengyan Wei, Zelong Cao, Liang Dong, Wei Wang, Mei Wei, Lishuang Ji, Linan Duan, Hui Sun, Mingqi Zheng
Article Number: 526
Published online on: 16 September 2025

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Role and clinical significance of the DNA methylation of 14‑3‑3σ in cancer (Review)

Danfeng He, Yi Hu, Di Niu
Article Number: 525
Published online on: 16 September 2025

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Article

Combination of immune checkpoint inhibitors and radiotherapy for bone metastases induces an abscopal effect and improves outcomes in non‑small cell lung cancer

Yohei Asano, Katsuhiro Hayashi, Shinji Miwa, Yuta Taniguchi, Miho Okuda, Isao Matsumoto, Seiji Yano, Satoru Demura
Article Number: 524
Published online on: 15 September 2025

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Expression of Concern Open Access

[Expression of Concern] Expression and significance of glucose‑regulated protein 78 in human osteosarcoma

Yongkui Zhang, Nianhu Li, Dongli Wang, Yiqiang Chen, Gang Li
Article Number: 523
Published online on: 15 September 2025

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Article Open Access

ARHGEF6 downregulation as a key mediator of tumor cell apoptosis in breast cancer

Yang Zhang, Dandan Zhou, Xuting Shen, Qinqin Song, Liuyang Yang, Wenbo Li, Xinxin Zhao, Wenxiang Fang, Bian Liu, Chencen Xing, Jisong Liu, Haoshu Fang, Qilun Zhang
Article Number: 522
Published online on: 12 September 2025

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Case Report Open Access

Chemotherapy drugs do not affect the production of hepatitis B surface antibodies: A case report

Fuqian Zhao, Junling Han, Daofu Shen, Rong Yu, Hongmei Niu, Yan Hui, Lei Wang
Article Number: 521
Published online on: 12 September 2025

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Review Open Access

Thyroid cancer: From molecular insights to therapy (Review)

Zhuozheng Li, Nuofan Wang, Xiao Li, Yongfang Xie, Zemin Dou, Hongbing Xin, Yuzhuo Lin, Yan Si, Tingting Feng, Guohui Wang
Article Number: 520
Published online on: 10 September 2025

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Review Open Access

Targeting menin in lysine methyltransferase 
2A/nucleophosmin-mutated leukemia: A novel strategy from epigenetic dysregulation to clinical therapy (Review)

Junjie Bi, Hong Zhou
Article Number: 519
Published online on: 10 September 2025

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Article Open Access

Meta‑analysis of the efficacy and safety of thoracic radiotherapy for extensive‑stage small cell lung cancer 
in the era of immunotherapy

Meiqiao Jiang, Lihua Shao, Yuanzhaoyun Long, Jinning Sun, Shihong Wei
Article Number: 518
Published online on: 09 September 2025

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Article Open Access

Proteomics reveals the regulation of ALG1 expression by lentivirus‑mediated THBS1 overexpression and its mechanism in meibomian gland carcinoma

Wei Wang, Hetong Wang, Guijia Wu, Xun Liu, Limin Zhu, Fang Tian, Tingting Lin
Article Number: 517
Published online on: 09 September 2025

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Case Report Open Access

Lymphedema is a rare manifestation of lymphoma: A case series and literature review

Kun Hao, Xingpeng Li, Jie Ren, Chunkai Yu, Li Zhang, Bin Li, Rengui Wang, Wenbin Shen, Yuguang Sun
Article Number: 516
Published online on: 09 September 2025

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Article Open Access

Exploring the clinical value of probiotics in the perioperative management of colorectal cancer: Meta‑analysis with trial sequential analysis

Yang Zhang, Jiepin Hu, Qiong Xu, Youjie Yu, Haozhe Yan, Wei Shao, Feng Zhang
Article Number: 515
Published online on: 09 September 2025

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Expression of Concern Open Access

[Expression of Concern] Lentivirus‑mediated RNA interference targeting UbcH10 reduces cell growth and invasion of human osteosarcoma cells via inhibition of Ki‑67 and matrix metalloproteinases

Shan-Tao Wang, Dan-Zhi Li, Jian-Min Li, Jun Fang, Hua-Zhuang Li, Pei-Jian Tong, Fu-Cun Liu
Article Number: 514
Published online on: 08 September 2025

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Article Open Access

Risks of haematological malignancies in patients treated for solid tumours associated with the use of pegylated granulocyte colony‑stimulating factors: A single centre study since 2005

Samuel Vokurka, Luboš Mastný, Vojtěch Kliment, Jana Kulhánková, Jana Dreslerová, Terezie Šamanová, Jindřich Fínek
Article Number: 513
Published online on: 05 September 2025

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Article

Novel biomarkers for prognosis in patients with localized prostate cancer 

Maria Goulielmaki, Savvas Stokidis, Theodoros Anagnostou, Angelos D. Gritzapis, Ourania E. Tsitsilonis, Constantin N. Baxevanis, Sotirios P. Fortis
Article Number: 512
Published online on: 04 September 2025

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Article Open Access

Meta‑analysis of the association between long non‑coding RNA maternally expressed gene 3 polymorphisms and cancer susceptibility

Yuan-Yuan Hu, Rui Chen, Xue-Feng Li, Yu-Ming Niu
Article Number: 511
Published online on: 04 September 2025

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Case Report Open Access

Adenoid cystic carcinoma of the breast with aggressive behavior: A case report and review of the literature

Hanin Lataifeh, Fawzi Abuhijla, Lina Wahbeh, Ramiz Abuhijlih, Wafa Asha, Abdullah Alzibdeh, Omar Jaber, Issa Mohamad, Hikmat Abdel‑Razeq
Article Number: 510
Published online on: 04 September 2025

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Case Report Open Access

Challenges associated with the treatment of E709K and L858R double mutation in lung adenocarcinoma: A case report and literature review

Jiangqin Song, Qin Wu, Lilin He, Lian Dong, Lamei Chen, Huashun Li, Kaiyuan Diao, Huabing Yuan
Article Number: 509
Published online on: 04 September 2025

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Review Open Access

Chemotherapy‑induced peripheral neuropathy in patients with breast cancer treated with taxanes (Review)

Mélanie Godiveau, Judith Passildas Jahanmohan, Catherine Abrial, Xavier Durando
Article Number: 508
Published online on: 02 September 2025

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Retraction Open Access

[Retracted] MicroRNA‑1180 is associated with growth and apoptosis in prostate cancer via TNF receptor associated factor 1 expression regulation and nuclear factor‑κB signaling pathway activation

Deyuan Zhu, Wenxi Gao, Zhongmin Zhang
Article Number: 507
Published online on: 01 September 2025

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Article Open Access

Analysis of prognostic factors and development of a predictive model following radical nephrectomy for Wilms tumor in children

Huaida Teng, Boren Hou, Kui Shi, Hang Li, Jiarong Wang, Junlei Shi, Deguang Meng
Article Number: 506
Published online on: 01 September 2025

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Case Report Open Access

Pneumocystis jirovecii pneumonia in a patient with HR+/HER2‑ advanced breast cancer following abemaciclib combined with endocrine therapy: A case report

Wei Hao, Sheng Liu, Yuenong Qin, Chenping Sun, Jijia Bao, Chunyu Wu
Article Number: 505
Published online on: 01 September 2025

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Article Open Access

Dynamic whole‑body positron emission tomography/computed tomography for predicting treatment response to chemoradiotherapy in patients with esophageal cancer

Moe Iwata, Yoshihiro Kurata, Koichi Hayano, Gaku Ohira, Toru Tochigi, Atsushi Hirata, Ryota Miura, Masaya Uesato, Takeshi Toyozumi, Yasunori Matsumoto, Akira Nakano, Tadashi Shiraishi, Nobufumi Sekino, Takashi Imori, Hisahiro Matsubara
Article Number: 504
Published online on: 01 September 2025

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Article Open Access

Prognostic value of inflammation‑ and nutrition‑based biomarkers in patients with recurrent or metastatic oral squamous cell carcinoma treated with immune checkpoint inhibitors: 
A retrospective study

Sachiko Yamasaki, Nanako Ito, Atsuko Hamada, Fumitaka Obayashi, Mirai Higaki, Takayuki Nakagawa, Shigehiro Ono, Koichi Koizumi, Tomonao Aikawa, Souichi Yanamoto
Article Number: 503
Published online on: 28 August 2025

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Article Open Access

A monocentric retrospective analysis of 10‑year overall survival after stereotactic body radiotherapy for medically inoperable non‑small cell lung cancer

Jörg Andreas Müller, Severin Guttenberger, Christine Kornhuber, Clara Pitzschel, Dirk Vordermark
Article Number: 502
Published online on: 27 August 2025

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Article Open Access

Reduction in surgical scope after neoadjuvant chemotherapy and immunotherapy for non‑small cell lung cancer

Wenyi Liu, Jinming Tang, Xu Li, Lianghui Gong, Desong Yang, Hui Yin, Wenxiang Wang, Baihua Zhang
Article Number: 501
Published online on: 27 August 2025

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Article

MRI‑based diffusion weighted imaging and diffusion kurtosis imaging grading of clear cell renal cell carcinoma using a deep learning classifier

Wenjing Zheng, Xin Luo, Yangyingqiu Liu, Chang Xu, Kaiwen Liu, Demin Kong, Peng Sun, Yuxuan Li, Xinying Shi, Ziyan Dong, Jinfeng Cao
Article Number: 500
Published online on: 27 August 2025

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Article Open Access

Quantitative analysis of lymphocyte exhaustion markers in patients with localized clear cell renal cell carcinoma

Raquel González‑Garza, Adrián Gutiérrez‑González, Nallely López‑López, Raquel Garza‑Guajardo, Juan Pablo Flores‑Gutiérrez, Mario César Salinas‑Carmona, Víctor Manuel Oyervides‑Juárez, Marco Alberto Ocaña‑Munguía, José Héctor Elizondo‑Jasso, Manuel Mejía‑Torres
Article Number: 499
Published online on: 27 August 2025

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Article Open Access

YTHDC2 inhibits HPV‑positive cervical cancer growth by suppressing SLC7A11 in a ferroptosis‑dependent manner

Li Ren, Junjun Zhang, Jinjin Yang, Li Ji, Jingjing Guo
Article Number: 498
Published online on: 27 August 2025

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Expression of Concern Open Access

[Expression of Concern] RUNX2 RNA interference inhibits the invasion of osteosarcoma

Heng Zeng, Xiaotao Xu
Article Number: 497
Published online on: 27 August 2025

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Case Report Open Access

Triple‑negative invasive lobular carcinoma presenting with synchronous gastric metastasis: A case report

Liangxue Zhu, Yajun Xing, Mingyun Wang
Article Number: 496
Published online on: 25 August 2025

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Case Report Open Access

Rare hepatic metastasis in classical adenoid cystic carcinoma of the breast: A case report

Xiaohui Huang, Yangjing Ou, Lin Tang, Wei Zhou, Taoli Wang, Miduo Tan
Article Number: 495
Published online on: 25 August 2025

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Article Open Access

Machine learning‑based model identifies a novel cuproptosis‑related mitochondrial gene signature with a key role in the prognosis and treatment of lung adenocarcinoma

Yi-Hao Liu, Wen-Hao Zhao, Ze-Xia Zhao, Zhi-Xuan Duan, Hua Huang, Cheng Ding, Ming-Hui Liu, Hong-Bing Zhang, Yong-Wen Li, Min Wang, Jun Chen, Hong-Lin Zhao
Article Number: 494
Published online on: 21 August 2025

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Review Open Access

The role of NR2F2 in cancer (Review)

Zi-Ning Liu, Xiao Yang
Article Number: 493
Published online on: 21 August 2025

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Review Open Access

Effects of lactylation on the hallmarks of cancer (Review)

Yujie Fan, Zhangda Chen, Jiaxin Li, Lidan Ding
Article Number: 492
Published online on: 20 August 2025

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Article Open Access

Comprehensive pan‑cancer analysis reveals ubiquitin‑conjugating enzyme 2T as a potential biomarker for prognosis and cancer immunity

Zhou Zhou, Yu-Hang Chen, An-Ni Xie, Ping Li
Article Number: 491
Published online on: 20 August 2025

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Expression of Concern Open Access

[Expression of Concern] Apelin‑13 induces autophagy in hepatoma HepG2 cells through ERK1/2 signaling pathway‑dependent upregulation of Beclin1

Qiulin Huang, Xuan Liu, Chao Cao, Junyue Lei, Dong Han, Guodong Chen, Jia Yu, Linxi Chen, Deguan Lv, Zhongyu Li
Article Number: 490
Published online on: 20 August 2025

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Article Open Access

Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Article

Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Article Open Access

Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Article Open Access

Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Article Open Access

Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Article Open Access

Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Review Open Access

Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Article Open Access

Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Review Open Access

Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Article Open Access

Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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Article Open Access

SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Article Open Access

Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Article Open Access

Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Article Open Access

Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Article Open Access

Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.2

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CiteScore Rank: Q2: #178/415 Oncology

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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