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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2025 Volume 30 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Prognostic model for predicting recurrence‑free survival in hepatocellular carcinoma using integrated analysis of single‑cell RNA‑sequencing and bulk RNA‑sequencing

Wentao Yang, Wenwen Lai, Qian Hu, Jingsheng Ma, Hailang Liu, Zelong Li, Qigen Li, Xiaohui Guo, Lin Zhong
Article Number: 537
Published online on: 22 September 2025

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Article Open Access

Progress of MRI‑based radiomics and deep learning for predicting the prognosis of locally advanced rectal cancer (Review)

Yuting Shi, Qiuhan Huang, Jiali Lyu, Tianjie Dong, Jihong Sun
Article Number: 536
Published online on: 19 September 2025

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Article Open Access

Preoperative C‑reactive protein‑albumin‑lymphocyte index predicts survival outcomes in patients with stage I‑III colorectal cancer: A retrospective cohort study

Jinquan Li, Xiaosheng Hu, Shanzhong Zhang
Article Number: 535
Published online on: 18 September 2025

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Review Open Access

Molecular mechanisms and functions of guanylate‑binding protein 2 in inflammation and cancer (Review)

Zeyu Liu, Shijun Peng, Jia Ouyang
Article Number: 534
Published online on: 18 September 2025

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Article Open Access

Identification of key molecules in micropapillary progression of lung adenocarcinoma: A comprehensive gene expression analysis study using the spatial gene expression solution methodology

Mai Matsumura, Hideaki Mitsui, Tetsukan Woo, Takehisa Suzuki, Hiromasa Arai, Chihiro Koike, Toshiaki Kataoka, Daisuke Motooka, Kiyoharu Fukushima, Koji Okudela
Article Number: 533
Published online on: 18 September 2025

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Review Open Access

Discoidin domain receptor tyrosine kinase 2: A new perspective on microenvironment remodeling and targeted therapy of solid tumors (Review)

Tong Lu, Huiying Guo, Hang Gong, Yaohui Ma, Yonggang Tian, Dekui Zhang
Article Number: 532
Published online on: 18 September 2025

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Article Open Access

Role of long non‑coding RNA‑mRNA interactions in resveratrol‑mediated inhibition of ovarian cancer cell proliferation

Weihua Zhu, Jiahui Feng, Yuanting Zhang, Qianqian Zhou, Herong Huang, Yu Yang
Article Number: 531
Published online on: 18 September 2025

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Article Open Access

Anticancer effects of thymoquinone on prostate cancer cells and natural killer cell activity

Nouf A. Aldarmahi, Nesrin I. Tarbiah, Nuha A. Alkhattabi, Huda F. Alshaibi
Article Number: 530
Published online on: 18 September 2025

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Case Report Open Access

Breast mucoepidermoid carcinoma: A case report

Min Xie, Chao-Chan Chen, Xiang-Yu Su, Zeng-Xiang Xu
Article Number: 529
Published online on: 17 September 2025

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Article Open Access

ERK‑driven autophagy enhances synergy of eribulin and cisplatin in triple‑negative breast cancer

Hyemi Ko, Myungsun Lee, Eunyoung Cha, Jinsun Lee
Article Number: 528
Published online on: 17 September 2025

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Review Open Access

Tumor‑associated microbiota: Multi‑cancer landscape, mechanistic insights and clinical translation (Review)

Jindi Yang, Yige Dong, Yi Chen, Hong Liang, Shengyu Rong, Zhe Liu, Qiulei Lang
Article Number: 527
Published online on: 16 September 2025

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Review Open Access

The advantages and challenges of sorafenib combination therapy: Drug resistance, toxicity and future directions (Review)

Mengyan Wei, Zelong Cao, Liang Dong, Wei Wang, Mei Wei, Lishuang Ji, Linan Duan, Hui Sun, Mingqi Zheng
Article Number: 526
Published online on: 16 September 2025

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Review Open Access

Role and clinical significance of the DNA methylation of 14‑3‑3σ in cancer (Review)

Danfeng He, Yi Hu, Di Niu
Article Number: 525
Published online on: 16 September 2025

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Article

Combination of immune checkpoint inhibitors and radiotherapy for bone metastases induces an abscopal effect and improves outcomes in non‑small cell lung cancer

Yohei Asano, Katsuhiro Hayashi, Shinji Miwa, Yuta Taniguchi, Miho Okuda, Isao Matsumoto, Seiji Yano, Satoru Demura
Article Number: 524
Published online on: 15 September 2025

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Expression of Concern Open Access

[Expression of Concern] Expression and significance of glucose‑regulated protein 78 in human osteosarcoma

Yongkui Zhang, Nianhu Li, Dongli Wang, Yiqiang Chen, Gang Li
Article Number: 523
Published online on: 15 September 2025

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Article Open Access

ARHGEF6 downregulation as a key mediator of tumor cell apoptosis in breast cancer

Yang Zhang, Dandan Zhou, Xuting Shen, Qinqin Song, Liuyang Yang, Wenbo Li, Xinxin Zhao, Wenxiang Fang, Bian Liu, Chencen Xing, Jisong Liu, Haoshu Fang, Qilun Zhang
Article Number: 522
Published online on: 12 September 2025

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Case Report Open Access

Chemotherapy drugs do not affect the production of hepatitis B surface antibodies: A case report

Fuqian Zhao, Junling Han, Daofu Shen, Rong Yu, Hongmei Niu, Yan Hui, Lei Wang
Article Number: 521
Published online on: 12 September 2025

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Review Open Access

Thyroid cancer: From molecular insights to therapy (Review)

Zhuozheng Li, Nuofan Wang, Xiao Li, Yongfang Xie, Zemin Dou, Hongbing Xin, Yuzhuo Lin, Yan Si, Tingting Feng, Guohui Wang
Article Number: 520
Published online on: 10 September 2025

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Review Open Access

Targeting menin in lysine methyltransferase 
2A/nucleophosmin-mutated leukemia: A novel strategy from epigenetic dysregulation to clinical therapy (Review)

Junjie Bi, Hong Zhou
Article Number: 519
Published online on: 10 September 2025

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Article Open Access

Meta‑analysis of the efficacy and safety of thoracic radiotherapy for extensive‑stage small cell lung cancer 
in the era of immunotherapy

Meiqiao Jiang, Lihua Shao, Yuanzhaoyun Long, Jinning Sun, Shihong Wei
Article Number: 518
Published online on: 09 September 2025

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Article Open Access

Proteomics reveals the regulation of ALG1 expression by lentivirus‑mediated THBS1 overexpression and its mechanism in meibomian gland carcinoma

Wei Wang, Hetong Wang, Guijia Wu, Xun Liu, Limin Zhu, Fang Tian, Tingting Lin
Article Number: 517
Published online on: 09 September 2025

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Case Report Open Access

Lymphedema is a rare manifestation of lymphoma: A case series and literature review

Kun Hao, Xingpeng Li, Jie Ren, Chunkai Yu, Li Zhang, Bin Li, Rengui Wang, Wenbin Shen, Yuguang Sun
Article Number: 516
Published online on: 09 September 2025

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Article Open Access

Exploring the clinical value of probiotics in the perioperative management of colorectal cancer: Meta‑analysis with trial sequential analysis

Yang Zhang, Jiepin Hu, Qiong Xu, Youjie Yu, Haozhe Yan, Wei Shao, Feng Zhang
Article Number: 515
Published online on: 09 September 2025

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Expression of Concern Open Access

[Expression of Concern] Lentivirus‑mediated RNA interference targeting UbcH10 reduces cell growth and invasion of human osteosarcoma cells via inhibition of Ki‑67 and matrix metalloproteinases

Shan-Tao Wang, Dan-Zhi Li, Jian-Min Li, Jun Fang, Hua-Zhuang Li, Pei-Jian Tong, Fu-Cun Liu
Article Number: 514
Published online on: 08 September 2025

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Article Open Access

Risks of haematological malignancies in patients treated for solid tumours associated with the use of pegylated granulocyte colony‑stimulating factors: A single centre study since 2005

Samuel Vokurka, Luboš Mastný, Vojtěch Kliment, Jana Kulhánková, Jana Dreslerová, Terezie Šamanová, Jindřich Fínek
Article Number: 513
Published online on: 05 September 2025

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Article

Novel biomarkers for prognosis in patients with localized prostate cancer 

Maria Goulielmaki, Savvas Stokidis, Theodoros Anagnostou, Angelos D. Gritzapis, Ourania E. Tsitsilonis, Constantin N. Baxevanis, Sotirios P. Fortis
Article Number: 512
Published online on: 04 September 2025

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Article Open Access

Meta‑analysis of the association between long non‑coding RNA maternally expressed gene 3 polymorphisms and cancer susceptibility

Yuan-Yuan Hu, Rui Chen, Xue-Feng Li, Yu-Ming Niu
Article Number: 511
Published online on: 04 September 2025

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Case Report Open Access

Adenoid cystic carcinoma of the breast with aggressive behavior: A case report and review of the literature

Hanin Lataifeh, Fawzi Abuhijla, Lina Wahbeh, Ramiz Abuhijlih, Wafa Asha, Abdullah Alzibdeh, Omar Jaber, Issa Mohamad, Hikmat Abdel‑Razeq
Article Number: 510
Published online on: 04 September 2025

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Case Report Open Access

Challenges associated with the treatment of E709K and L858R double mutation in lung adenocarcinoma: A case report and literature review

Jiangqin Song, Qin Wu, Lilin He, Lian Dong, Lamei Chen, Huashun Li, Kaiyuan Diao, Huabing Yuan
Article Number: 509
Published online on: 04 September 2025

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Review Open Access

Chemotherapy‑induced peripheral neuropathy in patients with breast cancer treated with taxanes (Review)

Mélanie Godiveau, Judith Passildas Jahanmohan, Catherine Abrial, Xavier Durando
Article Number: 508
Published online on: 02 September 2025

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Retraction Open Access

[Retracted] MicroRNA‑1180 is associated with growth and apoptosis in prostate cancer via TNF receptor associated factor 1 expression regulation and nuclear factor‑κB signaling pathway activation

Deyuan Zhu, Wenxi Gao, Zhongmin Zhang
Article Number: 507
Published online on: 01 September 2025

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Article Open Access

Analysis of prognostic factors and development of a predictive model following radical nephrectomy for Wilms tumor in children

Huaida Teng, Boren Hou, Kui Shi, Hang Li, Jiarong Wang, Junlei Shi, Deguang Meng
Article Number: 506
Published online on: 01 September 2025

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Case Report Open Access

Pneumocystis jirovecii pneumonia in a patient with HR+/HER2‑ advanced breast cancer following abemaciclib combined with endocrine therapy: A case report

Wei Hao, Sheng Liu, Yuenong Qin, Chenping Sun, Jijia Bao, Chunyu Wu
Article Number: 505
Published online on: 01 September 2025

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Article Open Access

Dynamic whole‑body positron emission tomography/computed tomography for predicting treatment response to chemoradiotherapy in patients with esophageal cancer

Moe Iwata, Yoshihiro Kurata, Koichi Hayano, Gaku Ohira, Toru Tochigi, Atsushi Hirata, Ryota Miura, Masaya Uesato, Takeshi Toyozumi, Yasunori Matsumoto, Akira Nakano, Tadashi Shiraishi, Nobufumi Sekino, Takashi Imori, Hisahiro Matsubara
Article Number: 504
Published online on: 01 September 2025

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Article Open Access

Prognostic value of inflammation‑ and nutrition‑based biomarkers in patients with recurrent or metastatic oral squamous cell carcinoma treated with immune checkpoint inhibitors: 
A retrospective study

Sachiko Yamasaki, Nanako Ito, Atsuko Hamada, Fumitaka Obayashi, Mirai Higaki, Takayuki Nakagawa, Shigehiro Ono, Koichi Koizumi, Tomonao Aikawa, Souichi Yanamoto
Article Number: 503
Published online on: 28 August 2025

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Article Open Access

A monocentric retrospective analysis of 10‑year overall survival after stereotactic body radiotherapy for medically inoperable non‑small cell lung cancer

Jörg Andreas Müller, Severin Guttenberger, Christine Kornhuber, Clara Pitzschel, Dirk Vordermark
Article Number: 502
Published online on: 27 August 2025

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Article Open Access

Reduction in surgical scope after neoadjuvant chemotherapy and immunotherapy for non‑small cell lung cancer

Wenyi Liu, Jinming Tang, Xu Li, Lianghui Gong, Desong Yang, Hui Yin, Wenxiang Wang, Baihua Zhang
Article Number: 501
Published online on: 27 August 2025

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Article

MRI‑based diffusion weighted imaging and diffusion kurtosis imaging grading of clear cell renal cell carcinoma using a deep learning classifier

Wenjing Zheng, Xin Luo, Yangyingqiu Liu, Chang Xu, Kaiwen Liu, Demin Kong, Peng Sun, Yuxuan Li, Xinying Shi, Ziyan Dong, Jinfeng Cao
Article Number: 500
Published online on: 27 August 2025

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Article Open Access

Quantitative analysis of lymphocyte exhaustion markers in patients with localized clear cell renal cell carcinoma

Raquel González‑Garza, Adrián Gutiérrez‑González, Nallely López‑López, Raquel Garza‑Guajardo, Juan Pablo Flores‑Gutiérrez, Mario César Salinas‑Carmona, Víctor Manuel Oyervides‑Juárez, Marco Alberto Ocaña‑Munguía, José Héctor Elizondo‑Jasso, Manuel Mejía‑Torres
Article Number: 499
Published online on: 27 August 2025

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Article Open Access

YTHDC2 inhibits HPV‑positive cervical cancer growth by suppressing SLC7A11 in a ferroptosis‑dependent manner

Li Ren, Junjun Zhang, Jinjin Yang, Li Ji, Jingjing Guo
Article Number: 498
Published online on: 27 August 2025

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Expression of Concern Open Access

[Expression of Concern] RUNX2 RNA interference inhibits the invasion of osteosarcoma

Heng Zeng, Xiaotao Xu
Article Number: 497
Published online on: 27 August 2025

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Case Report Open Access

Triple‑negative invasive lobular carcinoma presenting with synchronous gastric metastasis: A case report

Liangxue Zhu, Yajun Xing, Mingyun Wang
Article Number: 496
Published online on: 25 August 2025

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Case Report Open Access

Rare hepatic metastasis in classical adenoid cystic carcinoma of the breast: A case report

Xiaohui Huang, Yangjing Ou, Lin Tang, Wei Zhou, Taoli Wang, Miduo Tan
Article Number: 495
Published online on: 25 August 2025

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Article Open Access

Machine learning‑based model identifies a novel cuproptosis‑related mitochondrial gene signature with a key role in the prognosis and treatment of lung adenocarcinoma

Yi-Hao Liu, Wen-Hao Zhao, Ze-Xia Zhao, Zhi-Xuan Duan, Hua Huang, Cheng Ding, Ming-Hui Liu, Hong-Bing Zhang, Yong-Wen Li, Min Wang, Jun Chen, Hong-Lin Zhao
Article Number: 494
Published online on: 21 August 2025

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Review Open Access

The role of NR2F2 in cancer (Review)

Zi-Ning Liu, Xiao Yang
Article Number: 493
Published online on: 21 August 2025

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Review Open Access

Effects of lactylation on the hallmarks of cancer (Review)

Yujie Fan, Zhangda Chen, Jiaxin Li, Lidan Ding
Article Number: 492
Published online on: 20 August 2025

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Article Open Access

Comprehensive pan‑cancer analysis reveals ubiquitin‑conjugating enzyme 2T as a potential biomarker for prognosis and cancer immunity

Zhou Zhou, Yu-Hang Chen, An-Ni Xie, Ping Li
Article Number: 491
Published online on: 20 August 2025

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Expression of Concern Open Access

[Expression of Concern] Apelin‑13 induces autophagy in hepatoma HepG2 cells through ERK1/2 signaling pathway‑dependent upregulation of Beclin1

Qiulin Huang, Xuan Liu, Chao Cao, Junyue Lei, Dong Han, Guodong Chen, Jia Yu, Linxi Chen, Deguan Lv, Zhongyu Li
Article Number: 490
Published online on: 20 August 2025

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Journal Cover
January-2026 Volume 31 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Case Report Open Access

Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Article Open Access

Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Article Open Access

Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Review Open Access

Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Review Open Access

Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Article Open Access

Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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Article Open Access

TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Article Open Access

Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Article Open Access

Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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Review Open Access

From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Review Open Access

Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Article Open Access

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Article Open Access

Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Article Open Access

Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Article Open Access

Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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