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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2025 Volume 30 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Prognostic model for predicting recurrence‑free survival in hepatocellular carcinoma using integrated analysis of single‑cell RNA‑sequencing and bulk RNA‑sequencing

Wentao Yang, Wenwen Lai, Qian Hu, Jingsheng Ma, Hailang Liu, Zelong Li, Qigen Li, Xiaohui Guo, Lin Zhong
Article Number: 537
Published online on: 22 September 2025

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Article Open Access

Progress of MRI‑based radiomics and deep learning for predicting the prognosis of locally advanced rectal cancer (Review)

Yuting Shi, Qiuhan Huang, Jiali Lyu, Tianjie Dong, Jihong Sun
Article Number: 536
Published online on: 19 September 2025

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Article Open Access

Preoperative C‑reactive protein‑albumin‑lymphocyte index predicts survival outcomes in patients with stage I‑III colorectal cancer: A retrospective cohort study

Jinquan Li, Xiaosheng Hu, Shanzhong Zhang
Article Number: 535
Published online on: 18 September 2025

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Review Open Access

Molecular mechanisms and functions of guanylate‑binding protein 2 in inflammation and cancer (Review)

Zeyu Liu, Shijun Peng, Jia Ouyang
Article Number: 534
Published online on: 18 September 2025

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Article Open Access

Identification of key molecules in micropapillary progression of lung adenocarcinoma: A comprehensive gene expression analysis study using the spatial gene expression solution methodology

Mai Matsumura, Hideaki Mitsui, Tetsukan Woo, Takehisa Suzuki, Hiromasa Arai, Chihiro Koike, Toshiaki Kataoka, Daisuke Motooka, Kiyoharu Fukushima, Koji Okudela
Article Number: 533
Published online on: 18 September 2025

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Review Open Access

Discoidin domain receptor tyrosine kinase 2: A new perspective on microenvironment remodeling and targeted therapy of solid tumors (Review)

Tong Lu, Huiying Guo, Hang Gong, Yaohui Ma, Yonggang Tian, Dekui Zhang
Article Number: 532
Published online on: 18 September 2025

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Article Open Access

Role of long non‑coding RNA‑mRNA interactions in resveratrol‑mediated inhibition of ovarian cancer cell proliferation

Weihua Zhu, Jiahui Feng, Yuanting Zhang, Qianqian Zhou, Herong Huang, Yu Yang
Article Number: 531
Published online on: 18 September 2025

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Article Open Access

Anticancer effects of thymoquinone on prostate cancer cells and natural killer cell activity

Nouf A. Aldarmahi, Nesrin I. Tarbiah, Nuha A. Alkhattabi, Huda F. Alshaibi
Article Number: 530
Published online on: 18 September 2025

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Case Report Open Access

Breast mucoepidermoid carcinoma: A case report

Min Xie, Chao-Chan Chen, Xiang-Yu Su, Zeng-Xiang Xu
Article Number: 529
Published online on: 17 September 2025

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Article Open Access

ERK‑driven autophagy enhances synergy of eribulin and cisplatin in triple‑negative breast cancer

Hyemi Ko, Myungsun Lee, Eunyoung Cha, Jinsun Lee
Article Number: 528
Published online on: 17 September 2025

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Review Open Access

Tumor‑associated microbiota: Multi‑cancer landscape, mechanistic insights and clinical translation (Review)

Jindi Yang, Yige Dong, Yi Chen, Hong Liang, Shengyu Rong, Zhe Liu, Qiulei Lang
Article Number: 527
Published online on: 16 September 2025

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Review Open Access

The advantages and challenges of sorafenib combination therapy: Drug resistance, toxicity and future directions (Review)

Mengyan Wei, Zelong Cao, Liang Dong, Wei Wang, Mei Wei, Lishuang Ji, Linan Duan, Hui Sun, Mingqi Zheng
Article Number: 526
Published online on: 16 September 2025

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Review Open Access

Role and clinical significance of the DNA methylation of 14‑3‑3σ in cancer (Review)

Danfeng He, Yi Hu, Di Niu
Article Number: 525
Published online on: 16 September 2025

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Article

Combination of immune checkpoint inhibitors and radiotherapy for bone metastases induces an abscopal effect and improves outcomes in non‑small cell lung cancer

Yohei Asano, Katsuhiro Hayashi, Shinji Miwa, Yuta Taniguchi, Miho Okuda, Isao Matsumoto, Seiji Yano, Satoru Demura
Article Number: 524
Published online on: 15 September 2025

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Expression of Concern Open Access

[Expression of Concern] Expression and significance of glucose‑regulated protein 78 in human osteosarcoma

Yongkui Zhang, Nianhu Li, Dongli Wang, Yiqiang Chen, Gang Li
Article Number: 523
Published online on: 15 September 2025

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Article Open Access

ARHGEF6 downregulation as a key mediator of tumor cell apoptosis in breast cancer

Yang Zhang, Dandan Zhou, Xuting Shen, Qinqin Song, Liuyang Yang, Wenbo Li, Xinxin Zhao, Wenxiang Fang, Bian Liu, Chencen Xing, Jisong Liu, Haoshu Fang, Qilun Zhang
Article Number: 522
Published online on: 12 September 2025

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Case Report Open Access

Chemotherapy drugs do not affect the production of hepatitis B surface antibodies: A case report

Fuqian Zhao, Junling Han, Daofu Shen, Rong Yu, Hongmei Niu, Yan Hui, Lei Wang
Article Number: 521
Published online on: 12 September 2025

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Review Open Access

Thyroid cancer: From molecular insights to therapy (Review)

Zhuozheng Li, Nuofan Wang, Xiao Li, Yongfang Xie, Zemin Dou, Hongbing Xin, Yuzhuo Lin, Yan Si, Tingting Feng, Guohui Wang
Article Number: 520
Published online on: 10 September 2025

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Review Open Access

Targeting menin in lysine methyltransferase 
2A/nucleophosmin-mutated leukemia: A novel strategy from epigenetic dysregulation to clinical therapy (Review)

Junjie Bi, Hong Zhou
Article Number: 519
Published online on: 10 September 2025

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Article Open Access

Meta‑analysis of the efficacy and safety of thoracic radiotherapy for extensive‑stage small cell lung cancer 
in the era of immunotherapy

Meiqiao Jiang, Lihua Shao, Yuanzhaoyun Long, Jinning Sun, Shihong Wei
Article Number: 518
Published online on: 09 September 2025

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Article Open Access

Proteomics reveals the regulation of ALG1 expression by lentivirus‑mediated THBS1 overexpression and its mechanism in meibomian gland carcinoma

Wei Wang, Hetong Wang, Guijia Wu, Xun Liu, Limin Zhu, Fang Tian, Tingting Lin
Article Number: 517
Published online on: 09 September 2025

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Case Report Open Access

Lymphedema is a rare manifestation of lymphoma: A case series and literature review

Kun Hao, Xingpeng Li, Jie Ren, Chunkai Yu, Li Zhang, Bin Li, Rengui Wang, Wenbin Shen, Yuguang Sun
Article Number: 516
Published online on: 09 September 2025

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Article Open Access

Exploring the clinical value of probiotics in the perioperative management of colorectal cancer: Meta‑analysis with trial sequential analysis

Yang Zhang, Jiepin Hu, Qiong Xu, Youjie Yu, Haozhe Yan, Wei Shao, Feng Zhang
Article Number: 515
Published online on: 09 September 2025

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Expression of Concern Open Access

[Expression of Concern] Lentivirus‑mediated RNA interference targeting UbcH10 reduces cell growth and invasion of human osteosarcoma cells via inhibition of Ki‑67 and matrix metalloproteinases

Shan-Tao Wang, Dan-Zhi Li, Jian-Min Li, Jun Fang, Hua-Zhuang Li, Pei-Jian Tong, Fu-Cun Liu
Article Number: 514
Published online on: 08 September 2025

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Article Open Access

Risks of haematological malignancies in patients treated for solid tumours associated with the use of pegylated granulocyte colony‑stimulating factors: A single centre study since 2005

Samuel Vokurka, Luboš Mastný, Vojtěch Kliment, Jana Kulhánková, Jana Dreslerová, Terezie Šamanová, Jindřich Fínek
Article Number: 513
Published online on: 05 September 2025

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Article

Novel biomarkers for prognosis in patients with localized prostate cancer 

Maria Goulielmaki, Savvas Stokidis, Theodoros Anagnostou, Angelos D. Gritzapis, Ourania E. Tsitsilonis, Constantin N. Baxevanis, Sotirios P. Fortis
Article Number: 512
Published online on: 04 September 2025

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Article Open Access

Meta‑analysis of the association between long non‑coding RNA maternally expressed gene 3 polymorphisms and cancer susceptibility

Yuan-Yuan Hu, Rui Chen, Xue-Feng Li, Yu-Ming Niu
Article Number: 511
Published online on: 04 September 2025

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Case Report Open Access

Adenoid cystic carcinoma of the breast with aggressive behavior: A case report and review of the literature

Hanin Lataifeh, Fawzi Abuhijla, Lina Wahbeh, Ramiz Abuhijlih, Wafa Asha, Abdullah Alzibdeh, Omar Jaber, Issa Mohamad, Hikmat Abdel‑Razeq
Article Number: 510
Published online on: 04 September 2025

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Case Report Open Access

Challenges associated with the treatment of E709K and L858R double mutation in lung adenocarcinoma: A case report and literature review

Jiangqin Song, Qin Wu, Lilin He, Lian Dong, Lamei Chen, Huashun Li, Kaiyuan Diao, Huabing Yuan
Article Number: 509
Published online on: 04 September 2025

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Review Open Access

Chemotherapy‑induced peripheral neuropathy in patients with breast cancer treated with taxanes (Review)

Mélanie Godiveau, Judith Passildas Jahanmohan, Catherine Abrial, Xavier Durando
Article Number: 508
Published online on: 02 September 2025

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Retraction Open Access

[Retracted] MicroRNA‑1180 is associated with growth and apoptosis in prostate cancer via TNF receptor associated factor 1 expression regulation and nuclear factor‑κB signaling pathway activation

Deyuan Zhu, Wenxi Gao, Zhongmin Zhang
Article Number: 507
Published online on: 01 September 2025

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Article Open Access

Analysis of prognostic factors and development of a predictive model following radical nephrectomy for Wilms tumor in children

Huaida Teng, Boren Hou, Kui Shi, Hang Li, Jiarong Wang, Junlei Shi, Deguang Meng
Article Number: 506
Published online on: 01 September 2025

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Case Report Open Access

Pneumocystis jirovecii pneumonia in a patient with HR+/HER2‑ advanced breast cancer following abemaciclib combined with endocrine therapy: A case report

Wei Hao, Sheng Liu, Yuenong Qin, Chenping Sun, Jijia Bao, Chunyu Wu
Article Number: 505
Published online on: 01 September 2025

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Article Open Access

Dynamic whole‑body positron emission tomography/computed tomography for predicting treatment response to chemoradiotherapy in patients with esophageal cancer

Moe Iwata, Yoshihiro Kurata, Koichi Hayano, Gaku Ohira, Toru Tochigi, Atsushi Hirata, Ryota Miura, Masaya Uesato, Takeshi Toyozumi, Yasunori Matsumoto, Akira Nakano, Tadashi Shiraishi, Nobufumi Sekino, Takashi Imori, Hisahiro Matsubara
Article Number: 504
Published online on: 01 September 2025

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Article Open Access

Prognostic value of inflammation‑ and nutrition‑based biomarkers in patients with recurrent or metastatic oral squamous cell carcinoma treated with immune checkpoint inhibitors: 
A retrospective study

Sachiko Yamasaki, Nanako Ito, Atsuko Hamada, Fumitaka Obayashi, Mirai Higaki, Takayuki Nakagawa, Shigehiro Ono, Koichi Koizumi, Tomonao Aikawa, Souichi Yanamoto
Article Number: 503
Published online on: 28 August 2025

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Article Open Access

A monocentric retrospective analysis of 10‑year overall survival after stereotactic body radiotherapy for medically inoperable non‑small cell lung cancer

Jörg Andreas Müller, Severin Guttenberger, Christine Kornhuber, Clara Pitzschel, Dirk Vordermark
Article Number: 502
Published online on: 27 August 2025

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Article Open Access

Reduction in surgical scope after neoadjuvant chemotherapy and immunotherapy for non‑small cell lung cancer

Wenyi Liu, Jinming Tang, Xu Li, Lianghui Gong, Desong Yang, Hui Yin, Wenxiang Wang, Baihua Zhang
Article Number: 501
Published online on: 27 August 2025

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Article

MRI‑based diffusion weighted imaging and diffusion kurtosis imaging grading of clear cell renal cell carcinoma using a deep learning classifier

Wenjing Zheng, Xin Luo, Yangyingqiu Liu, Chang Xu, Kaiwen Liu, Demin Kong, Peng Sun, Yuxuan Li, Xinying Shi, Ziyan Dong, Jinfeng Cao
Article Number: 500
Published online on: 27 August 2025

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Article Open Access

Quantitative analysis of lymphocyte exhaustion markers in patients with localized clear cell renal cell carcinoma

Raquel González‑Garza, Adrián Gutiérrez‑González, Nallely López‑López, Raquel Garza‑Guajardo, Juan Pablo Flores‑Gutiérrez, Mario César Salinas‑Carmona, Víctor Manuel Oyervides‑Juárez, Marco Alberto Ocaña‑Munguía, José Héctor Elizondo‑Jasso, Manuel Mejía‑Torres
Article Number: 499
Published online on: 27 August 2025

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Article Open Access

YTHDC2 inhibits HPV‑positive cervical cancer growth by suppressing SLC7A11 in a ferroptosis‑dependent manner

Li Ren, Junjun Zhang, Jinjin Yang, Li Ji, Jingjing Guo
Article Number: 498
Published online on: 27 August 2025

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Expression of Concern Open Access

[Expression of Concern] RUNX2 RNA interference inhibits the invasion of osteosarcoma

Heng Zeng, Xiaotao Xu
Article Number: 497
Published online on: 27 August 2025

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Case Report Open Access

Triple‑negative invasive lobular carcinoma presenting with synchronous gastric metastasis: A case report

Liangxue Zhu, Yajun Xing, Mingyun Wang
Article Number: 496
Published online on: 25 August 2025

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Case Report Open Access

Rare hepatic metastasis in classical adenoid cystic carcinoma of the breast: A case report

Xiaohui Huang, Yangjing Ou, Lin Tang, Wei Zhou, Taoli Wang, Miduo Tan
Article Number: 495
Published online on: 25 August 2025

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Article Open Access

Machine learning‑based model identifies a novel cuproptosis‑related mitochondrial gene signature with a key role in the prognosis and treatment of lung adenocarcinoma

Yi-Hao Liu, Wen-Hao Zhao, Ze-Xia Zhao, Zhi-Xuan Duan, Hua Huang, Cheng Ding, Ming-Hui Liu, Hong-Bing Zhang, Yong-Wen Li, Min Wang, Jun Chen, Hong-Lin Zhao
Article Number: 494
Published online on: 21 August 2025

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Review Open Access

The role of NR2F2 in cancer (Review)

Zi-Ning Liu, Xiao Yang
Article Number: 493
Published online on: 21 August 2025

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Review Open Access

Effects of lactylation on the hallmarks of cancer (Review)

Yujie Fan, Zhangda Chen, Jiaxin Li, Lidan Ding
Article Number: 492
Published online on: 20 August 2025

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Article Open Access

Comprehensive pan‑cancer analysis reveals ubiquitin‑conjugating enzyme 2T as a potential biomarker for prognosis and cancer immunity

Zhou Zhou, Yu-Hang Chen, An-Ni Xie, Ping Li
Article Number: 491
Published online on: 20 August 2025

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Expression of Concern Open Access

[Expression of Concern] Apelin‑13 induces autophagy in hepatoma HepG2 cells through ERK1/2 signaling pathway‑dependent upregulation of Beclin1

Qiulin Huang, Xuan Liu, Chao Cao, Junyue Lei, Dong Han, Guodong Chen, Jia Yu, Linxi Chen, Deguan Lv, Zhongyu Li
Article Number: 490
Published online on: 20 August 2025

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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