Journal Articles
Review
Insights into roles of the miR-1, -133 and -206 family in gastric cancer (Review)
Meng Xie, Dafydd Alwyn Dart, Sioned Owen, Xianzi Wen, Jiafu Ji, Wenguo Jiang
Pages: 1191-1198 Published online on: 27 June 2016
Review
The biological role of epithelial-mesenchymal transition in lung cancer (Review)
Woo Jung Sung, Hongtae Kim, Kwan-Kyu Park
Pages: 1199-1206 Published online on: 21 July 2016
Review
Long noncoding RNAs in digestive system cancers: Functional roles, molecular mechanisms, and clinical implications (Review)
Min Fu, Chen Zou, Lei Pan, Wei Liang, Hui Qian, Wenrong Xu, Pengcheng Jiang, Xu Zhang
Pages: 1207-1218 Published online on: 11 July 2016
Review
mTOR signaling in osteosarcoma: Oncogenesis and therapeutic aspects (Review)
Kai Hu, Hai-Bo Dai, Zhi-Long Qiu
Pages: 1219-1225 Published online on: 08 July 2016
Review
Regulation of the miRNA expression by TEL/AML1, BCR/ABL, MLL/AF4 and TCF3/PBX1 oncoproteins in acute lymphoblastic leukemia (Review)
Jorge Organista-Nava, Yazmín Gómez-Gómez, Berenice Illades-Aguiar, Marco Antonio Leyva-Vázquez
Pages: 1226-1232 Published online on: 19 July 2016
Article
Curcumin reduces the expression of survivin, leading to enhancement of arsenic trioxide-induced apoptosis in myelodysplastic syndrome and leukemia stem-like cells
Yingjian Zeng, Guangyang Weng, Jiaxin Fan, Zhangqiu Li, Jianwei Wu, Yuanming Li, Rong Zheng, Pingfang Xia, Kunyuan Guo
Pages: 1233-1242 Published online on: 15 July 2016
Article
Enhancing the treatment effect on melanoma by heat shock protein 70-peptide complexes purified from human melanoma cell lines
Yanwei Gao, Weishi Gao, Xia Chen, Nier Cha, Xiaoli Wang, Xiangdong Jia, Bingping Wang, Meng Ren, Jun Ren
Pages: 1243-1250 Published online on: 19 July 2016
Article
Myofibroblasts of the muscle layer stimulate the malignant potential of colorectal cancer
Masafumi Takatsuna, Satoko Morohashi, Tadashi Yoshizawa, Hideaki Hirai, Toshihiro Haga, Rie Ota, Yunyan Wu, Hajime Morohashi, Kenichi Hakamada, Shuji Terai, Hiroshi Kijima
Pages: 1251-1257 Published online on: 11 July 2016
Article
Proteomic analysis of imatinib-resistant CML-T1 cells reveals calcium homeostasis as a potential therapeutic target
O. Toman, T. Kabickova, O. Vit, R. Fiser, K. Machova Polakova, J. Zach, J. Linhartova, D. Vyoral, J. Petrak
Pages: 1258-1268 Published online on: 18 July 2016
Article
Isoalantolactone inhibits the migration and invasion of human breast cancer MDA-MB-231 cells via suppression of the p38 MAPK/NF-κB signaling pathway
Jing Wang, Li Cui, Liang Feng, Zhenhai Zhang, Jie Song, Dan Liu, Xiaobin Jia
Pages: 1269-1276 Published online on: 20 July 2016
Article
GFAP expression is regulated by Pax3 in brain glioma stem cells
Xing Su, Xiaojiang Liu, Lanchun Ni, Wei Shi, Hui Zhu, Jinlong Shi, Jian Chen, Zhikai Gu, Yilu Gao, Qing Lan, Qingfeng Huang
Pages: 1277-1284 Published online on: 07 July 2016
Article
MYO6 knockdown inhibits the growth and induces the apoptosis of prostate cancer cells by decreasing the phosphorylation of ERK1/2 and PRAS40
Dong Wang, Libing Zhu, Min Liao, Tengyue Zeng, Wenli Zhuo, Shunliang Yang, Weizhen Wu
Pages: 1285-1292 Published online on: 29 June 2016
Article
MicroRNA-497 inhibits the proliferation, migration and invasion of human bladder transitional cell carcinoma cells by targeting E2F3 Corrigendum in /10.3892/or.2020.7466
Yixiao Zhang, Zhe Zhang, Zhenhua Li, Daxin Gong, Bo Zhan, Xiaojun Man, Chuize Kong
Pages: 1293-1300 Published online on: 08 July 2016
Article
Overexpression of seven in absentia homolog 2 protein in human breast cancer tissues is associated with the promotion of tumor cell malignant behavior in in vitro
Jie Sun, Xiaojuan Zhang, Yanchun Han, Juan Zhen, Yuan Meng, Min Song
Pages: 1301-1312 Published online on: 25 July 2016
Article
Glycoprotein screening in colorectal cancer based on differentially expressed Tn antigen
Hongyun Wei, Zongyong Cheng, Chunhui Ouyang, Yu Zhang, Yanyan Hu, Shuijiao Chen, Chunlian Wang, Fanggen Lu, Jie Zhang, Yongjun Wang, Xiaowei Liu
Pages: 1313-1324 Published online on: 14 July 2016
Article
Nutlin-3 reverses the epithelial-mesenchymal transition in gemcitabine-resistant hepatocellular carcinoma cells
Qiong Wu, Xi Wang, Jing Liu, Jiyue Zheng, Yang Liu, Yumei Li, Fang Su, Weili Ou, Rui Wang
Pages: 1325-1332 Published online on: 08 July 2016
Article
Oxymatrine inhibits epithelial-mesenchymal transition through regulation of NF-κB signaling in colorectal cancer cells
Li Liang, Jiean Huang
Pages: 1333-1338 Published online on: 11 July 2016
Article
VEGFR-1 targeted DNAzyme via transcatheter arterial delivery influences tumor vasculature assessed through dynamic contrast-enhanced magnetic resonance imaging
Liqing Zhang, Wei Zhao, Chen Liang, Xiaoping Yi, Yigang Pei, Yiting Lin, Jiang He, Wenzheng Li
Pages: 1339-1344 Published online on: 12 July 2016
Article
Celecoxib suppresses fibroblast growth factor-2 expression in pancreatic ductal adenocarcinoma PANC-1 cells
Jing Li, Miaosha Luo, Yan Wang, Boxin Shang, Lei Dong
Pages: 1345-1352 Published online on: 08 July 2016
Article
Transcription factor c-jun regulates β3Gn-T8 expression in gastric cancer cell line SGC-7901
Zhi Jiang, Zhenhua Liu, Shitao Zou, Jianlong Ni, Li Shen, Yinghui Zhou, Dong Hua, Shiliang Wu
Pages: 1353-1360 Published online on: 21 July 2016
Article
Sulforaphane-cysteine suppresses invasion via downregulation of galectin-1 in human prostate cancer DU145 and PC3 cells
Hua Tian, Yan Zhou, Gaoxiang Yang, Yang Geng, Sai Wu, Yabin Hu, Kai Lin, Wei Wu
Pages: 1361-1368 Published online on: 15 July 2016
Article
Gastrin promotes the metastasis of gastric carcinoma through the β-catenin/TCF-4 pathway
Kun Zhuang, Yuan Yan, Xin Zhang, Jun Zhang, Lingxia Zhang, Kun Han
Pages: 1369-1376 Published online on: 15 July 2016
Article
Effects of active bufadienolide compounds on human cancer cells and CD4+CD25+Foxp3+ regulatory T cells in mitogen-activated human peripheral blood mononuclear cells
Bo Yuan, Jing He, Keishi Kisoh, Hideki Hayashi, Sachiko Tanaka, Nan Si, Hai-Yu Zhao, Toshihiko Hirano, Baolin Bian, Norio Takagi
Pages: 1377-1384 Published online on: 18 July 2016
Article
miR-451 acts as a suppressor of angiogenesis in hepatocellular carcinoma by targeting the IL-6R-STAT3 pathway
Xuemin Liu, Anpeng Zhang, Junxi Xiang, Yi Lv, Xufeng Zhang
Pages: 1385-1392 Published online on: 25 July 2016
Article
Genetically engineered Newcastle disease virus expressing human interferon-λ1 induces apoptosis in gastric adenocarcinoma cells and modulates the Th1/Th2 immune response
Xuefeng Bu, Mi Li, Yinghai Zhao, Sha Liu, Mubin Wang, Jinying Ge, Zhigao Bu, Yulan Yan
Pages: 1393-1402 Published online on: 11 July 2016
Article
ACE2 overexpression inhibits acquired platinum resistance-induced tumor angiogenesis in NSCLC
Qijian Cheng, Ling Zhou, Jianping Zhou, Huanying Wan, Qingyun Li, Yun Feng
Pages: 1403-1410 Published online on: 22 July 2016
Article
RNA interference against TRIM29 inhibits migration and invasion of colorectal cancer cells
Weihong Xu, Bin Xu, Yiting Yao, Xiaoling Yu, Hua Cao, Jun Zhang, Jie Liu, Huiming Sheng
Pages: 1411-1418 Published online on: 15 July 2016
Article
Thyroid hormone receptor β1 suppresses proliferation and migration by inhibiting PI3K/Akt signaling in human colorectal cancer cells
Lei Zhu, Guangang Tian, Qin Yang, Gejing De, Zhigang Zhang, Yahui Wang, Huizhen Nie, Yanli Zhang, Xiaomei Yang, Jun Li
Pages: 1419-1426 Published online on: 11 July 2016
Article
ALK ambiguous-positive non-small cell lung cancers are tumors challenged by diagnostic and therapeutic issues
Arnaud Uguen, Sophie Andrieu‑Key, Florence Vergne, Renaud Descourt, Gilles Quéré, Isabelle Quintin‑Roué, Stéphane Key, Paul Guéguen, Matthieu Talagas, Marc De Braekeleer, Pascale Marcorelles
Pages: 1427-1434 Published online on: 21 July 2016
Article
Establishment and characterization of a novel human cholangiocarcinoma cell line with high metastatic activity
Kwuntida Uthaisar, Kulthida Vaeteewoottacharn, Wunchana Seubwai, Chutima Talabnin, Kanlayanee Sawanyawisuth, Sumalee Obchoei, Ratthaphol Kraiklang, Seiji Okada, Sopit Wongkham
Pages: 1435-1446 Published online on: 25 July 2016
Article
Platycodin D, a metabolite of Platycodin grandiflorum, inhibits highly metastatic MDA-MB-231 breast cancer growth in vitro and in vivo by targeting the MDM2 oncogene
Ya Kong, Zong-Liang Lu, Jia-Jia Wang, Rui Zhou, Jing Guo, Jie Liu, Hai-Lan Sun, He Wang, Wei Song, Jian Yang, Hong-Xia Xu
Pages: 1447-1456 Published online on: 13 July 2016
Article
Crocodile blood extract induces the apoptosis of lung cancer cells through PTEN activity
Yuqian Ou, Wing Shing Ho
Pages: 1457-1466 Published online on: 05 July 2016
Article
miR-338 inhibits the metastasis of lung cancer by targeting integrin β3
Xiao Chen, Li Wei, Song Zhao
Pages: 1467-1474 Published online on: 11 July 2016
Article
MicroRNA-27a-3p regulates epithelial to mesenchymal transition via targeting YAP1 in oral squamous cell carcinoma cells
Guang Zeng, Wenxing Xun, Kewen Wei, Yongjin Yang, Huan Shen
Pages: 1475-1482 Published online on: 07 July 2016
Article
Effect of saracatinib on pulmonary metastases from hepatocellular carcinoma
Ju Xiong, Jin-Sheng Wu, Shan-Shan Mao, Xiang-Nan Yu, Xiao-Xi Huang
Pages: 1483-1490 Published online on: 22 July 2016
Article
Huaier aqueous extract inhibits proliferation and metastasis of tuberous sclerosis complex cell models through downregulation of JAK2/STAT3 and MAPK signaling pathways
Ailin Yang, Haitao Fan, Yunfang Zhao, Xiaojun Zha, Hongbing Zhang, Zhongdong Hu, Pengfei Tu
Pages: 1491-1498 Published online on: 25 July 2016
Article
Triptolide induces the cell apoptosis of osteosarcoma cells through the TRAIL pathway
Xingwei Zhao, Qiang Zhang, Liang Chen
Pages: 1499-1505 Published online on: 21 July 2016
Article
Downregulation of nucleolar and spindle-associated protein 1 expression suppresses cell migration, proliferation and invasion in renal cell carcinoma Corrigendum in /10.3892/or.2020.7875
Lu Fang, Meng Zhang, Lei Chen, Hu Xiong, Yukun Ge, Wei Lu, Xun Wu, Baoli Heng, Dexin Yu, Song Wu
Pages: 1506-1516 Published online on: 20 July 2016
Article
Coix seed emulsion synergistically enhances the antitumor activity of gemcitabine in pancreatic cancer through abrogation of NF-κB signaling
Yafang Qian, Bo Yang, Yang Xiong, Mancang Gu
Pages: 1517-1525 Published online on: 21 July 2016
Article
A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway
Bingling Dai, Wenjie Wang, Yujiao Ma, Rui Liu, Yanmin Zhang
Pages: 1526-1534 Published online on: 21 July 2016
Article
SnoN suppresses TGF-β-induced epithelial-mesenchymal transition and invasion of bladder cancer in a TIF1γ-dependent manner
Xinbao Yin, Chuanshen Xu, Xueping Zheng, Huiyang Yuan, Ming Liu, Yue Qiu, Jun Chen
Pages: 1535-1541 Published online on: 15 July 2016
Article
Identifying survival-associated ceRNA clusters in cholangiocarcinoma
Ming Wan, Fu-Min Zhang, Zheng-Long Li, Peng-Cheng Kang, Ping-Ming Jiang, Yi-Min Wang, Zhi-Dong Wang, Xiang-Yu Zhong, Chun-Long Li, Hao Wang, Shi-Yong Zhao, Yun-Fu Cui
Pages: 1542-1550 Published online on: 12 July 2016
Article
TIM-3 promotes the metastasis of esophageal squamous cell carcinoma by targeting epithelial-mesenchymal transition via the Akt/GSK-3β/Snail signaling pathway
Baoen Shan, Hongwei Man, Junfeng Liu, Ling Wang, Tienian Zhu, Ming Ma, Zhili Xv, Xinran Chen, Xingxiao Yang, Pengfei Li
Pages: 1551-1561 Published online on: 14 July 2016
Article
Classical and atypical resistance of cancer cells as a target for resveratrol
Sylwia Borska, Monika Pedziwiatr, Monika Danielewicz, Katarzyna Nowinska, Bartosz Pula, Malgorzata Drag-Zalesinska, Mateusz Olbromski, Agnieszka Gomulkiewicz, Piotr Dziegiel
Pages: 1562-1568 Published online on: 11 July 2016
Article
Inhibition of miR-7 promotes angiogenesis in human umbilical vein endothelial cells by upregulating VEGF via KLF4
Yi-Ze Li, Lei Wen, Xu Wei, Qian-Rong Wang, Long-Wen Xu, Hong-Mei Zhang, Wen-Chao Liu
Pages: 1569-1575 Published online on: 05 July 2016
Article
Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib
Wei-Jun Wei, Chen-Tian Shen, Hong-Jun Song, Zhong-Ling Qiu, Quan-Yong Luo
Pages: 1576-1584 Published online on: 07 July 2016
Article
GLIPR1 inhibits the proliferation and induces the differentiation of cancer-initiating cells by regulating miR-16 in osteosarcoma
Jian Dong, Binna Bi, Lianhai Zhang, Kaituo Gao
Pages: 1585-1591 Published online on: 19 July 2016
Article
Analysis of the gene expression profile in response to human epididymis protein 4 in epithelial ovarian cancer cells
Liancheng Zhu, Qian Guo, Shan Jin, Huilin Feng, Huiyu Zhuang, Cong Liu, Mingzi Tan, Juanjuan Liu, Xiao Li, Bei Lin
Pages: 1592-1604 Published online on: 11 July 2016
Article
Plumbagin reduces chronic lymphocytic leukemia cell survival by downregulation of Bcl-2 but upregulation of the Bax protein level
Chunling Fu, Yanqing Gong, Xuanxuan Shi, Zengtian Sun, Mingshan Niu, Wei Sang, Linyan Xu, Feng Zhu, Ying Wang, Kailin Xu
Pages: 1605-1611 Published online on: 19 July 2016
Article
The role of PAQR3 gene promoter hypermethylation in breast cancer and prognosis
Jinpeng Chen, Feiran Wang, Junfei Xu, Zhixian He, Yuhua Lu, Zhiwei Wang
Pages: 1612-1618 Published online on: 19 July 2016
Article
Overexpression of CAP1 and its significance in tumor cell proliferation, migration and invasion in glioma
Yue-Chao Fan, Chen-Chen Cui, Yi-Shuo Zhu, Lei Zhang, Meng Shi, Jin-Song Yu, Jin Bai, Jun-Nian Zheng
Pages: 1619-1625 Published online on: 13 July 2016
Article
Amyloid precursor protein cooperates with c-KIT mutation/overexpression to regulate cell apoptosis in AML1-ETO-positive leukemia via the PI3K/AKT signaling pathway
Guopan Yu, Changxin Yin, Ling Jiang, Zhongxin Zheng, Zhixiang Wang, Chunli Wang, Hongsheng Zhou, Xuejie Jiang, Qifa Liu, Fanyi Meng
Pages: 1626-1632 Published online on: 21 July 2016
Article
CCY-1a-E2 induces G2/M phase arrest and apoptotic cell death in HL-60 leukemia cells through cyclin-dependent kinase 1 signaling and the mitochondria-dependent caspase pathway
Chin‑Fen Lin, Jai‑Sing Yang, Chingju Lin, Fuu‑Jen Tsai, Chi‑Cheng Lu, Miau‑Rong Lee
Pages: 1633-1639 Published online on: 25 July 2016
Article
A novel double carbonyl analog of curcumin induces the apoptosis of human lung cancer H460 cells via the activation of the endoplasmic reticulum stress signaling pathway
Hui Ye, Xiaoyan Wei, Zhankun Wang, Shanshan Zhang, Jiye Ren, Song Yao, Lingyi Shi, Lizhu Yang, Peihong Qiu, Jianzhang Wu, Guang Liang
Pages: 1640-1648 Published online on: 30 June 2016
Article
Involvement of endoplasmic reticulum stress and p53 in lncRNA MEG3-induced human hepatoma HepG2 cell apoptosis
Rui‑Pei Chen, Zhen‑Lun Huang, Li‑Xuan Liu, Meng‑Qi Xiang, Guo‑Ping Li, Jia‑Lin Feng, Bin Liu, Ling‑Fei Wu
Pages: 1649-1657 Published online on: 08 July 2016
Article
IKK inhibitor suppresses epithelial-mesenchymal transition and induces cell death in prostate cancer
Hao Ping, Feiya Yang, Mingshuai Wang, Yinong Niu, Nianzeng Xing
Pages: 1658-1664 Published online on: 07 July 2016
Article
Low expression lncRNA RPLP0P2 is associated with poor prognosis and decreased cell proliferation and adhesion ability in lung adenocarcinoma
Jie Chen, Lijuan Hu, Jian Chen, Fang Wu, Dongwei Hu, Gang Xu, Peiwu Zhu, Yumin Wang
Pages: 1665-1671 Published online on: 22 July 2016
Article
GATA binding protein 2 overexpression is associated with poor prognosis in KRAS mutant colorectal cancer
Kai Xu, Jiayuan Wang, Jing Gao, Jiabo Di, Beihai Jiang, Lei Chen, Zaozao Wang, Aidong Wang, Fan Wu, Wei Wu, Lin Shen, Xiangqian Su
Pages: 1672-1678 Published online on: 21 July 2016
Article
The role of lncRNA MALAT1 in bone metastasis in patients with non-small cell lung cancer
Meijuan Liu, Wanli Sun, Yongquan Liu, Xiuhong Dong
Pages: 1679-1685 Published online on: 29 June 2016
Article
CXCR3A contributes to the invasion and metastasis of gastric cancer cells
Chenggang Yang, Wanlei Zheng, Wenfeng Du
Pages: 1686-1692 Published online on: 19 July 2016
Article
miR-92b targets DAB2IP to promote EMT in bladder cancer migration and invasion
Jun Huang, Bin Wang, Ke Hui, Jin Zeng, Jinhai Fan, Xinyang Wang, Jer-Tsong Hsieh, Dalin He, Kaijie Wu
Pages: 1693-1701 Published online on: 15 July 2016
Article
MicroRNA-520a attenuates proliferation of Raji cells through inhibition of AKT1/NF-κB and PERK/eIF2α signaling pathway Retraction in /10.3892/or.2024.8706
Xiaojuan Wang, Pei Wang, Yan Zhu, Zhi Zhang, Jinqian Zhang, Hongwei Wang
Pages: 1702-1708 Published online on: 25 July 2016
Article
MicroRNA-1207-5p inhibits hepatocellular carcinoma cell growth and invasion through the fatty acid synthase-mediated Akt/mTOR signalling pathway
Gang Zhao, Lei Dong, Haitao Shi, Hong Li, Xiaolan Lu, Xiaoyan Guo, Jinhai Wang
Pages: 1709-1716 Published online on: 19 July 2016
Article
STC-1 expression is upregulated through an Akt/NF-κB-dependent pathway in triple-negative breast cancer cells
Myeongjin Jeon, Jeonghun Han, Seok Jin Nam, Jeong Eon Lee, Sangmin Kim
Pages: 1717-1722 Published online on: 25 July 2016
Article
Transglutaminase 3 protein modulates human esophageal cancer cell growth by targeting the NF-κB signaling pathway
Wei Li, Zhongmian Zhang, Wenchao Zhao, Na Han
Pages: 1723-1730 Published online on: 08 July 2016
Article
Synergistic inhibition of characteristics of liver cancer stem-like cells with a combination of sorafenib and 8-bromo-7-methoxychrysin in SMMC-7721 cell line
Hui Zou, Xiaozheng Cao, Qiao Xiao, Xifeng Sheng, Kaiqun Ren, Meifang Quan, Zhengwei Song, Duo Li, Yu Zheng, Wenbin Zeng, Jianguo Cao, Yaojin Peng
Pages: 1731-1738 Published online on: 25 July 2016
Article
Breast cancer-associated high-order SNP-SNP interaction of CXCL12/CXCR4-related genes by an improved multifactor dimensionality reduction (MDR-ER)
Ou‑Yang Fu, Hsueh‑Wei Chang, Yu‑Da Lin, Li‑Yeh Chuang, Ming‑Feng Hou, Cheng‑Hong Yang
Pages: 1739-1747 Published online on: 21 July 2016
Article
Prognostic value of microRNA-203a expression in breast cancer
Bruno Costa Gomes, Manuela Martins, Paulina Lopes, Inês Morujão, Mário Oliveira, António Araújo, José Rueff, António Sebastião Rodrigues
Pages: 1748-1756 Published online on: 05 July 2016
Article
β2-adrenergic receptor activation promotes the proliferation of A549 lung cancer cells via the ERK1/2/CREB pathway
Ping Hu, Jingjing He, Shiling Liu, Meng Wang, Bingxing Pan, Wenhua Zhang
Pages: 1757-1763 Published online on: 22 July 2016
Article
