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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2015 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Regulation mechanism of Fbxw7-related signaling pathways (Review)

Zhenyu Zhou, Chuanchao He, Jie Wang
Pages: 2215-2224
Published online on: 26 August 2015

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Review

IκB kinase α functions as a tumor suppressor in epithelial-derived tumors through an NF-κB-independent pathway (Review)

Yuxin Xie, Keqi Xie, Qiheng Gou, Nianyong Chen
Pages: 2225-2232
Published online on: 26 August 2015

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Review

Cancer stem cells: The potential of carbon ion beam radiation and new radiosensitizers (Review)

Sung-Jae Baek, Hideshi Ishii, Keisuke Tamari, Kazuhiko Hayashi, Naohiro Nishida, Masamitsu Konno, Koichi Kawamoto, Jun Koseki, Takahito Fukusumi, Shinichiro Hasegawa, Hisataka Ogawa, Atsushi Hamabe, Masaaki Miyo, Kozo Noguchi, Yuji Seo, Yuichiro Doki, Masaki Mori, Kazuhiko Ogawa
Pages: 2233-2237
Published online on: 01 September 2015

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Article Open Access

HDAC1 and HDAC2 independently predict mortality in hepatocellular carcinoma by a competing risk regression model in a Southeast Asian population

Ser Yeng Ler, Carol Ho Wing Leung, Lay Wai Khin, Guo-Dong Lu, Manuel Salto-Tellez, Mikael Hartman, Philip Tsau Choong Iau, Celestial T. Yap, Shing Chuan Hooi
Pages: 2238-2250
Published online on: 09 September 2015

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Article Open Access

Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway

Haruna Kawano, Yoshitaka Ito, Fumio Kanai, Eri Nakamura, Norihiro Tada, Setsuo Takai, Shigeo Horie, Toshiyuki Kobayashi, Okio Hino
Pages: 2251-2258
Published online on: 08 September 2015

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Article Open Access

Promoting roles of the secreted frizzled-related protein 2 as a Wnt agonist in lung cancer cells

Xiaomin Xiao, Yingying Xiao, Ruiling Wen, Yuhua Zhang, Xiaoxia Li, Haoli Wang, Jianqiong Huang, Jiahua Liu, Tiandi Long, Jun Tang
Pages: 2259-2266
Published online on: 21 August 2015

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Article Open Access

RNAi-mediated RPL34 knockdown suppresses the growth of human gastric cancer cells

Hui Liu, Shaohua Liang, Xi Yang, Zhaoning Ji, Wenying Zhao, Xiaobing Ye, Jing Rui
Pages: 2267-2272
Published online on: 21 August 2015

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Article Open Access

Insulin-like growth factor binding protein-3 mediates interleukin-24-induced apoptosis through inhibition of the mTOR pathway in prostate cancer

Yuefeng Du, Qingzhi Long, Ying Shi, Xiaogang Liu, Xudong Li, Jin Zeng, Yongguang Gong, Lei Li, Xinyang Wang, Dalin He
Pages: 2273-2281
Published online on: 13 August 2015

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Article Open Access

CD24 expression as a marker for predicting clinical outcome and invasive activity in uterine cervical cancer

Tomohito Tanaka, Yoshito Terai, Yuhei Kogata, Keisuke Ashihara, Kazuya Maeda, Satoe Fujiwara, Saha Yoo, Yoshimichi Tanaka, Satoshi Tsunetoh, Hiroshi Sasaki, Masanori Kanemura, Akiko Tanabe, Masahide Ohmichi
Pages: 2282-2288
Published online on: 08 September 2015

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Article Open Access

Immunotherapy for Lewis lung carcinoma utilizing dendritic cells infected with CK19 gene recombinant adenoviral vectors

Q. F. Sun, X. N. Zhao, C. L. Peng, Y. T. Hao, Y. P. Zhao, N. Jiang, H. Xue, J. Z. Guo, C. H. Yun, B. Cong, X. G. Zhao
Pages: 2289-2295
Published online on: 27 August 2015

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Article

Aberrantly elevated redox sensing factor Nrf2 promotes cancer stem cell survival via enhanced transcriptional regulation of ABCG2 and Bcl-2/Bmi-1 genes

Yan Jia, Jun Chen, He Zhu, Zan-Hui Jia, Man-Hua Cui
Pages: 2296-2304
Published online on: 20 August 2015

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Article

Inhibition of Src family kinases overcomes anoikis resistance induced by spheroid formation and facilitates cisplatin-induced apoptosis in human mesothelioma cells

Ryoji Eguchi, Yumiko Fujita, Chiharu Tabata, Hiroyasu Ogawa, Ichiro Wakabayashi, Takashi Nakano, Yoshihiro Fujimori
Pages: 2305-2310
Published online on: 13 August 2015

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Article

Increased efficiency of testicular tumor chemotherapy by ultrasound microbubble-mediated targeted transfection of siMDR1

Yun He, Yang Bi, Xiao-Juan Ji, Guanghui Wei
Pages: 2311-2318
Published online on: 09 September 2015

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Article

Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer

Douglas W. Ball, Ning Jin, Ping Xue, Sheetal Bhan, Shabina R. Ahmed, D. Marc Rosen, Adam Schayowitz, Douglas P. Clark, Barry D. Nelkin
Pages: 2319-2324
Published online on: 26 August 2015

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Article

Upregulated KLK10 inhibits esophageal cancer proliferation and enhances cisplatin sensitivity in vitro

Lei Li, Nan Xu, Ning Fan, Qingchun Meng, Wenchao Luo, Lijia Lv, Wei Ma, Xiaoyu Liu, Lu Liu, Fei Xu, Huaxin Wang, Weifeng Mao, Yan Li
Pages: 2325-2332
Published online on: 20 August 2015

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Article

Aberrant hypomethylation and overexpression of the eyes absent homologue 2 suppresses tumor cell growth of human lung adenocarcinoma cells

Tangxin Gao, Shangyong Zheng, Qian Li, Pengzhan Ran, Lijuan Sun, Yuncang Yuan, Chunjie Xiao
Pages: 2333-2342
Published online on: 02 September 2015

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Article

A novel mutation in SIRT1-AS leading to a decreased risk of HCC

Junbin Liu, Weihong Wu, Junhua Jin
Pages: 2343-2350
Published online on: 19 August 2015

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Article

Radiosensitization of non-small cell lung cancer by kaempferol

Wei-Ting Kuo, Yuan-Chung Tsai, His-Chin Wu, Yung-Jen Ho, Yueh-Sheng Chen, Chen-Han Yao, Chun-Hsu Yao
Pages: 2351-2356
Published online on: 19 August 2015

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Article

p120-catenin participates in the progress of gastric cancer through regulating the Rac1 and Pak1 signaling pathway

Tong-Fei Li, Sheng-Hui Qin, Xu-Zhi Ruan, Xi Wang
Pages: 2357-2364
Published online on: 26 August 2015

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Article

IL-17A-producing T cells and associated cytokines are involved in the progression of gastric cancer

Fengyun Zhong, Dawei Cui, Hong Tao, Hong Du, Chungen Xing
Pages: 2365-2374
Published online on: 07 September 2015

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Article

Ursolic acid inhibits the proliferation of human ovarian cancer stem-like cells through epithelial-mesenchymal transition

Jie Zhang, Wenjing Wang, Lin Qian, Qiuwan Zhang, Dongmei Lai, Cong Qi
Pages: 2375-2384
Published online on: 20 August 2015

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Article

Expression of RAP1B is associated with poor prognosis and promotes an aggressive phenotype in gastric cancer

Ya Yang, Min Li, Yan Yan, Jia Zhang, Kai Sun, Jing‑Kun Qu, Jian-Sheng Wang, Xiao-Yi Duan
Pages: 2385-2394
Published online on: 01 September 2015

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Article

An HCG-rich microenvironment contributes to ovarian cancer cell differentiation into endothelioid cells in a three-dimensional culture system

Min Su, Chao Fan, Sainan Gao, Aiguo Shen, Xiaoying Wang, Yuquan Zhang
Pages: 2395-2402
Published online on: 20 August 2015

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Article

Sp1 cooperates with Sp3 to upregulate MALAT1 expression in human hepatocellular carcinoma

Ziling Huang, Lanshan Huang, Siqiao Shen, Jia Li, Huiping Lu, Weijia Mo, Yiwu Dang, Dianzhong Luo, Gang Chen, Zhenbo Feng
Pages: 2403-2412
Published online on: 08 September 2015

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Article

Exogenous hydrogen sulfide promotes C6 glioma cell growth through activation of the p38 MAPK/ERK1/2-COX-2 pathways

Yulan Zhen, Wei Zhang, Chujie Liu, Jing He, Yun Lu, Ruixian Guo, Jianqiang Feng, Ying Zhang, Jingfu Chen
Pages: 2413-2422
Published online on: 08 September 2015

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Article

Mitogen-activated protein kinase phosphatase 1 is involved in tamoxifen resistance in MCF7 cells

Gang Ma, Yixia Pan, Can Zhou, Ruifang Sun, Jingjing Bai, Peijun Liu, Yu Ren, Jianjun He
Pages: 2423-2430
Published online on: 02 September 2015

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Article

Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces cell cycle arrest and apoptosis via the downregulation of Akt in human lung cancer cells

Hyun Sook Lim, Yong Jung Kang, Bokyung Sung, Seon Hee Kim, Min Jeong Kim, Hye Rim Kim, Seong Jin Kim, Yung Hyun Choi, Hyung Ryong Moon, Hae Young Chung, Nam Deuk Kim
Pages: 2431-2438
Published online on: 19 August 2015

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Article

Improved sensitivity and specificity for prostate cancer diagnosis based on the urine PCA3/PSA ratio acquired by sequence‑specific RNA capture

Kewen Zheng, Yaling Dou, Linfu He, Hanzhong Li, Zhicai Zhang, Yu Chen, Ali Ye, Wenjing Liu, Lingjun Kong
Pages: 2439-2444
Published online on: 09 September 2015

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Article

Suppression of LPS-induced epithelial-mesenchymal transition by aqueous extracts of Prunella vulgaris through inhibition of the NF-κB/Snail signaling pathway and regulation of EMT-related protein expression

In-Hye Cho, Eun Hyang Jang, Darong Hong, Bom Jung, Min-Ju Park, Jong-Ho Kim
Pages: 2445-2450
Published online on: 21 August 2015

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Article

ADAM15 targets MMP9 activity to promote lung cancer cell invasion

Dan-Dan Dong, Hui Zhou, Gao Li
Pages: 2451-2460
Published online on: 14 August 2015

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Article

Silibinin induces apoptosis through inhibition of the mTOR-GLI1-BCL2 pathway in renal cell carcinoma

Zhenkun Ma, Wei Liu, Jin Zeng, Jiancheng Zhou, Peng Guo, Hongjun Xie, Zhao Yang, Long Zheng, Shan Xu, Xinyang Wang, Luke S. Chang, Dalin He, Lei Li
Pages: 2461-2468
Published online on: 26 August 2015

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Article

Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells

Chen Zhang, Yaping Tian, Feiyu Song, Changhao Fu, Bo Han, Yi Wang
Pages: 2469-2476
Published online on: 08 September 2015

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Article

Analysis of the differential secretome of nasopharyngeal carcinoma cell lines CNE-2R and CNE-2

Ze-Tan Chen, Ling Li, Ya Guo, Song Qu, Wei Zhao, Hao Chen, Fang Su, Jun Yin, Qi-Yan Mo, Xiao-Dong Zhu
Pages: 2477-2488
Published online on: 08 September 2015

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Article

PEITC inhibits human brain glioblastoma GBM 8401 cell migration and invasion through the inhibition of uPA, Rho A, and Ras with inhibition of MMP-2, -7 and -9 gene expression

Yu-Cheng Chou, Meng-Ya Chang, Mei-Jen Wang, Fu-Shun Yu, Hsin-Chung Liu, Tomor Harnod, Chih-Huang Hung, Hsu-Tung Lee, Jing-Gung Chung
Pages: 2489-2496
Published online on: 08 September 2015

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Article

CD90 is upregulated in gastric cancer tissues and inhibits gastric cancer cell apoptosis by modulating the expression level of SPARC protein

Guang Chao Zhu, Lu Gao, Junyu He, Yuehua Long, Shan Liao, Haiyun Wang, Xujuan Li, Wei Yi, Zhen Pei, Minghua Wu, Juanjuan Xiang, Shuping Peng, Jian Ma, Ming Zhou, Zhaoyang Zeng, Bo Xiang, Wei Xiong, Ke Tang, Li Cao, Xiaoling Li, Guiyuan Li, Yanhong Zhou
Pages: 2497-2506
Published online on: 01 September 2015

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Article

RGS22 inhibits pancreatic adenocarcinoma cell migration through the G12/13 α subunit/F-actin pathway

Yanqiu Hu, Jun Xing, Ling Chen, Ying Zheng, Zuomin Zhou
Pages: 2507-2514
Published online on: 19 August 2015

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Article

Overexpression of CIP2A in clear cell renal cell carcinoma promotes cellular epithelial-mesenchymal transition and is associated with poor prognosis

Qizhen Tang, Qifei Wang, Guang Zeng, Quanlin Li, Tao Jiang, Zhiwei Zhang, Wei Zheng, Kenan Wang
Pages: 2515-2522
Published online on: 21 August 2015

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Article

Inhibition of cell proliferation and metastasis of human hepatocellular carcinoma by miR-137 is regulated by CDC42

Ming Gao, Liying Liu, Shenglei Li, Xudong Zhang, Zhiwei Chang, Mingzhi Zhang
Pages: 2523-2532
Published online on: 09 September 2015

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Article

Induction of apoptosis by an ethanol extract of Poria cocos Wolf. in human leukemia U937 cells

Yung Hyun Choi
Pages: 2533-2540
Published online on: 08 September 2015

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Article

Involvement of nuclear receptor RZR/RORγ in melatonin-induced HIF-1α inactivation in SGC-7901 human gastric cancer cells

Ri-Xiong Wang, Hui Liu, Li Xu, Hui Zhang, Rui-Xiang Zhou
Pages: 2541-2546
Published online on: 01 September 2015

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Article

N‑acetyl-S-(p-chlorophenylcarbamoyl)cysteine induces mitochondrial-mediated apoptosis and suppresses migration in melanoma cells

Wei Chen, Zhiming Jiang, Xiaoying Zhang, Jianguo Feng, Yutian Ling
Pages: 2547-2556
Published online on: 09 September 2015

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Article

Downregulation of VMP1 confers aggressive properties to colorectal cancer

Xian-Zhi Guo, Xiao-Lei Ye, Wei-Zhong Xiao, Xue-Ni Wei, Qing-Hua You, Xiao‑Hang Che, Yan-Jun Cai, Fang Chen, Hao Yuan, Xiao-Jian Liu, Ming-Hua Yu
Pages: 2557-2566
Published online on: 01 September 2015

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Article

Anti-CD3 x EGFR bispecific antibody redirects cytokine-induced killer cells to glioblastoma in vitro and in vivo

Pan Ma, Qiang He, Wei Li, Xianliang Li, Huamin Han, Mengmeng Jin, Changzhen Liu, Hua Tao, Juan Ma, Bin Gao
Pages: 2567-2575
Published online on: 28 August 2015

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Article

MicroRNA-92a contributes to tumor growth of human hepatocellular carcinoma by targeting FBXW7 Corrigendum in /10.3892/or.2023.8596

Wei Yang, Changwei Dou, Yufeng Wang, Yuli Jia, Chao Li, Xin Zheng, Kangsheng Tu
Pages: 2576-2584
Published online on: 19 August 2015

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Article

Integrated analysis of the differential cellular and EBV miRNA expression profiles in microdissected nasopharyngeal carcinoma and non-cancerous nasopharyngeal tissues

Xun-Xun Wan, Hong Yi, Jia-Quan Qu, Qiu-Yan He, Zhi-Qiang Xiao
Pages: 2585-2601
Published online on: 01 September 2015

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Article

Hexane extract from Sargassum serratifolium inhibits the cell proliferation and metastatic ability of human glioblastoma U87MG cells

Chang-Won Kang, Min-Seok Park, Nan-Hee Kim, Ji-Hyun Lee, Chul-Woong Oh, Hyeung-Rak Kim, Gun-Do Kim
Pages: 2602-2608
Published online on: 21 August 2015

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Article

Cancer predisposing BARD1 mutations affect exon skipping and are associated with overexpression of specific BARD1 isoforms

Magdalena Ratajska, Magdalena Matusiak, Alina Kuzniacka, Bartosz Wasag, Izabela Brozek, Wojciech Biernat, Magdalena Koczkowska, Jaroslaw Debniak, Marcin Sniadecki, Piotr Kozlowski, Katarzyna Klonowska, Maxim Pilyugin, Dariusz Wydra, Geoff Laurent, Janusz Limon, Irmgard Irminger-Finger
Pages: 2609-2617
Published online on: 01 September 2015

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Article

Lentiviral-mediated multiple gene transfer to chondrocytes promotes chondrocyte differentiation and bone formation in rabbit bone marrow-derived mesenchymal stem cells

Ping Liu, Liang Sun, Hui Chen, Shui Sun, Dongsheng Zhou, Bo Pang, Jian Wang
Pages: 2618-2626
Published online on: 01 September 2015

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Article

Identification of biomarkers with a tumor stage-dependent expression and exploration of the mechanism involved in laryngeal squamous cell carcinoma

Lian Hui, Ning Yang, Huijun Yang, Xing Guo, Xuejun Jang
Pages: 2627-2635
Published online on: 27 August 2015

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Article

Expression and promoter methylation of Wnt inhibitory factor-1 in the development of oral submucous fibrosis

Shanghui Zhou, Ling Chen, Mubarak Mashrah, Yun Zhu, Zhijing He, Yuhua Hu, Tingxiu Xiang, Zhigang Yao, Feng Guo, Chenping Zhang
Pages: 2636-2642
Published online on: 09 September 2015

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Article

GdCl3 suppresses the malignant potential of hepatocellular carcinoma by inhibiting the expression of CD206 in tumor‑associated macrophages

Fangyu Zhu, Xiangnan Li, Yong Jiang, Haoran Zhu, Haolong Zhang, Chengyao Zhang, Yu Zhao, Fang Luo
Pages: 2643-2655
Published online on: 09 September 2015

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Article

Hyperthermia induces apoptosis by targeting Survivin in esophageal cancer

Sida Qin, Chongwen Xu, Shuo Li, Xifang Wang, Xin Sun, Peili Wang, Boxiang Zhang, Hong Ren
Pages: 2656-2664
Published online on: 08 September 2015

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Article

miR-1291 targets mucin 1 inhibiting cell proliferation and invasion to promote cell apoptosis in esophageal squamous cell carcinoma

Hailan Luo, Wentao Guo, Fei Wang, Yanjie You, Jianguo Wang, Xudong Chen, Jihong Wang, Yuanyuan Wang, Yuwen Du, Xiaonan Chen, Changgui Xue, Guohua Song, Fuqing Wang
Pages: 2665-2673
Published online on: 19 August 2015

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Article

Farnesoid X receptor signal is involved in deoxycholic acid-induced intestinal metaplasia of normal human gastric epithelial cells

Shu Li, Xin Chen, Lu Zhou, Bang-Mao Wang
Pages: 2674-2682
Published online on: 19 August 2015

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Article

Fibroblast growth factor 19 is correlated with an unfavorable prognosis and promotes progression by activating fibroblast growth factor receptor 4 in advanced-stage serous ovarian cancer

Lingling Hu, Lanxiang Cong
Pages: 2683-2691
Published online on: 20 August 2015

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Article

Genistein enhances TRAIL-induced cancer cell death via inactivation of autophagic flux

Uddin Md. Nazim, Sang-Youel Park
Pages: 2692-2698
Published online on: 07 September 2015

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Article

New mouse xenograft model modulated by tumor-associated fibroblasts for human multi-drug resistance in cancer

Yan Ma, Zhiqiang Lin, John K. Fallon, Qiang Zhao, Dan Liu, Yongjun Wang, Feng Liu
Pages: 2699-2705
Published online on: 09 September 2015

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MicroRNA-1908 is upregulated in human osteosarcoma and regulates cell proliferation and migration by repressing PTEN expression

Hongmou Yuan, Yanjun Gao
Pages: 2706-2714
Published online on: 01 September 2015

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Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells

Dong Shen, Cheng-Cheng Guo, Jing Wang, Zhi-Kun Qiu, Ke Sai, Qun-Ying Yang, Yin-Sheng Chen, Fu-Rong Chen, Jie Wang, Lawrence Panasci, Zhong-Ping Chen
Pages: 2715-2721
Published online on: 27 August 2015

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SET and MYND domain-containing protein 3 is overexpressed in human glioma and contributes to tumorigenicity Retraction in /10.3892/or.2024.8825

Bin Dai, Weiqing Wan, Peng Zhang, Yisong Zhang, Changcun Pan, Guolu Meng, Xinru Xiao, Zhen Wu, Wang Jia, Junting Zhang, Liwei Zhang
Pages: 2722-2730
Published online on: 01 September 2015

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IM-412 inhibits the invasion of human breast carcinoma cells by blocking FGFR-mediated signaling

Seung-Youn Jung, Jae Youn Yi, Mi-Hyoung Kim, Kyung-Hee Song, Seong-Mook Kang, Jiyeon Ahn, Sang-Gu Hwang, Ky-Youb Nam, Jie-Young Song
Pages: 2731-2737
Published online on: 08 September 2015

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Sequential gemcitabine and tamoxifen treatment enhances apoptosis and blocks transformation in bladder cancer cells

Hisashi Takeuchi, Chinedu O. Mmeje, Goodwin G. Jinesh, Rikiya Taoka, Ashish M. Kamat
Pages: 2738-2744
Published online on: 21 August 2015

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Hypoxia-induced fibroblast growth factor 11 stimulates capillary-like endothelial tube formation

Jimin Yang, Woo Jean Kim, Hyoung Oh Jun, Eun Ju Lee, Kyeong Won Lee, Jae-Yeon Jeong, Sae-Won Lee
Pages: 2745-2751
Published online on: 24 August 2015

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Time-dependent release of extracellular vesicle subpopulations in tumor CABA I cells

Ilaria Giusti, Marianna Di Francesco, Laura Cantone, Sandra D'Ascenzo, Valentina Bollati, Gaspare Carta, Vincenza Dolo
Pages: 2752-2759
Published online on: 12 August 2015

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The significance of the altered expression of lysophosphatidic acid receptors, autotaxin and phospholipase A2 as the potential biomarkers in type 1 endometrial cancer biology

Tomasz Wasniewski, Izabela Woclawek-Potocka, Dorota Boruszewska, Ilona Kowalczyk-Zieba, Emilia Sinderewicz, Katarzyna Grycmacher
Pages: 2760-2767
Published online on: 20 August 2015

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Isolation and characterization of circulating micro(nano)vesicles in the plasma of colorectal cancer patients and their interactions with tumor cells

Małgorzata Stec, Monika Baj-Krzyworzeka, Jarosław Baran, Kazimierz Węglarczyk, Maria Zembala, Jakub Barbasz, Antoni Szczepanik, Marek Zembala
Pages: 2768-2775
Published online on: 26 August 2015

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HAX-1 inhibits apoptosis in prostate cancer through the suppression of caspase-9 activation

Jiliang Yan, Chunyan Ma, Jian Cheng, Zhengguo Li, Chao Liu
Pages: 2776-2781
Published online on: 13 August 2015

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Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of PI3K/Akt signaling pathway

Hai Jin, Fan Qiao, Yan Wang, Yongdong Xu, Yan Shang
Pages: 2782-2789
Published online on: 08 September 2015

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Cytoprotective effects of ferritin on doxorubicin-induced breast cancer cell death

Benjaporn Buranrat, James R. Connor
Pages: 2790-2796
Published online on: 08 September 2015

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MicroRNA-128 suppresses cell growth and metastasis in colorectal carcinoma by targeting IRS1 Retraction in /10.3892/or.2021.8140

Lan Wu, Bo Shi, Kexin Huang, Guoyu Fan
Pages: 2797-2805
Published online on: 08 September 2015

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma

Yue Chen, Jun Wu, Danxia Zhu, Lu Jiang, Jian Wang, Dachuan Zhang, Wenting He
Article Number: 37
Published online on: 02 January 2026

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Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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Retraction Open Access

[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício De Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑De‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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