Journal Articles
Review
Regulation mechanism of Fbxw7-related signaling pathways (Review)
Zhenyu Zhou, Chuanchao He, Jie Wang
Pages: 2215-2224 Published online on: 26 August 2015
Review
IκB kinase α functions as a tumor suppressor in epithelial-derived tumors through an NF-κB-independent pathway (Review)
Yuxin Xie, Keqi Xie, Qiheng Gou, Nianyong Chen
Pages: 2225-2232 Published online on: 26 August 2015
Review
Cancer stem cells: The potential of carbon ion beam radiation and new radiosensitizers (Review)
Sung-Jae Baek, Hideshi Ishii, Keisuke Tamari, Kazuhiko Hayashi, Naohiro Nishida, Masamitsu Konno, Koichi Kawamoto, Jun Koseki, Takahito Fukusumi, Shinichiro Hasegawa, Hisataka Ogawa, Atsushi Hamabe, Masaaki Miyo, Kozo Noguchi, Yuji Seo, Yuichiro Doki, Masaki Mori, Kazuhiko Ogawa
Pages: 2233-2237 Published online on: 01 September 2015
Article
HDAC1 and HDAC2 independently predict mortality in hepatocellular carcinoma by a competing risk regression model in a Southeast Asian population
Ser Yeng Ler, Carol Ho Wing Leung, Lay Wai Khin, Guo-Dong Lu, Manuel Salto-Tellez, Mikael Hartman, Philip Tsau Choong Iau, Celestial T. Yap, Shing Chuan Hooi
Pages: 2238-2250 Published online on: 09 September 2015
Article
Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway
Haruna Kawano, Yoshitaka Ito, Fumio Kanai, Eri Nakamura, Norihiro Tada, Setsuo Takai, Shigeo Horie, Toshiyuki Kobayashi, Okio Hino
Pages: 2251-2258 Published online on: 08 September 2015
Article
Promoting roles of the secreted frizzled-related protein 2 as a Wnt agonist in lung cancer cells
Xiaomin Xiao, Yingying Xiao, Ruiling Wen, Yuhua Zhang, Xiaoxia Li, Haoli Wang, Jianqiong Huang, Jiahua Liu, Tiandi Long, Jun Tang
Pages: 2259-2266 Published online on: 21 August 2015
Article
RNAi-mediated RPL34 knockdown suppresses the growth of human gastric cancer cells
Hui Liu, Shaohua Liang, Xi Yang, Zhaoning Ji, Wenying Zhao, Xiaobing Ye, Jing Rui
Pages: 2267-2272 Published online on: 21 August 2015
Article
Insulin-like growth factor binding protein-3 mediates interleukin-24-induced apoptosis through inhibition of the mTOR pathway in prostate cancer
Yuefeng Du, Qingzhi Long, Ying Shi, Xiaogang Liu, Xudong Li, Jin Zeng, Yongguang Gong, Lei Li, Xinyang Wang, Dalin He
Pages: 2273-2281 Published online on: 13 August 2015
Article
CD24 expression as a marker for predicting clinical outcome and invasive activity in uterine cervical cancer
Tomohito Tanaka, Yoshito Terai, Yuhei Kogata, Keisuke Ashihara, Kazuya Maeda, Satoe Fujiwara, Saha Yoo, Yoshimichi Tanaka, Satoshi Tsunetoh, Hiroshi Sasaki, Masanori Kanemura, Akiko Tanabe, Masahide Ohmichi
Pages: 2282-2288 Published online on: 08 September 2015
Article
Immunotherapy for Lewis lung carcinoma utilizing dendritic cells infected with CK19 gene recombinant adenoviral vectors
Q. F. Sun, X. N. Zhao, C. L. Peng, Y. T. Hao, Y. P. Zhao, N. Jiang, H. Xue, J. Z. Guo, C. H. Yun, B. Cong, X. G. Zhao
Pages: 2289-2295 Published online on: 27 August 2015
Article
Aberrantly elevated redox sensing factor Nrf2 promotes cancer stem cell survival via enhanced transcriptional regulation of ABCG2 and Bcl-2/Bmi-1 genes
Yan Jia, Jun Chen, He Zhu, Zan-Hui Jia, Man-Hua Cui
Pages: 2296-2304 Published online on: 20 August 2015
Article
Inhibition of Src family kinases overcomes anoikis resistance induced by spheroid formation and facilitates cisplatin-induced apoptosis in human mesothelioma cells
Ryoji Eguchi, Yumiko Fujita, Chiharu Tabata, Hiroyasu Ogawa, Ichiro Wakabayashi, Takashi Nakano, Yoshihiro Fujimori
Pages: 2305-2310 Published online on: 13 August 2015
Article
Increased efficiency of testicular tumor chemotherapy by ultrasound microbubble-mediated targeted transfection of siMDR1
Yun He, Yang Bi, Xiao-Juan Ji, Guanghui Wei
Pages: 2311-2318 Published online on: 09 September 2015
Article
Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer
Douglas W. Ball, Ning Jin, Ping Xue, Sheetal Bhan, Shabina R. Ahmed, D. Marc Rosen, Adam Schayowitz, Douglas P. Clark, Barry D. Nelkin
Pages: 2319-2324 Published online on: 26 August 2015
Article
Upregulated KLK10 inhibits esophageal cancer proliferation and enhances cisplatin sensitivity in vitro
Lei Li, Nan Xu, Ning Fan, Qingchun Meng, Wenchao Luo, Lijia Lv, Wei Ma, Xiaoyu Liu, Lu Liu, Fei Xu, Huaxin Wang, Weifeng Mao, Yan Li
Pages: 2325-2332 Published online on: 20 August 2015
Article
Aberrant hypomethylation and overexpression of the eyes absent homologue 2 suppresses tumor cell growth of human lung adenocarcinoma cells
Tangxin Gao, Shangyong Zheng, Qian Li, Pengzhan Ran, Lijuan Sun, Yuncang Yuan, Chunjie Xiao
Pages: 2333-2342 Published online on: 02 September 2015
Article
A novel mutation in SIRT1-AS leading to a decreased risk of HCC
Junbin Liu, Weihong Wu, Junhua Jin
Pages: 2343-2350 Published online on: 19 August 2015
Article
Radiosensitization of non-small cell lung cancer by kaempferol
Wei-Ting Kuo, Yuan-Chung Tsai, His-Chin Wu, Yung-Jen Ho, Yueh-Sheng Chen, Chen-Han Yao, Chun-Hsu Yao
Pages: 2351-2356 Published online on: 19 August 2015
Article
p120-catenin participates in the progress of gastric cancer through regulating the Rac1 and Pak1 signaling pathway
Tong-Fei Li, Sheng-Hui Qin, Xu-Zhi Ruan, Xi Wang
Pages: 2357-2364 Published online on: 26 August 2015
Article
IL-17A-producing T cells and associated cytokines are involved in the progression of gastric cancer
Fengyun Zhong, Dawei Cui, Hong Tao, Hong Du, Chungen Xing
Pages: 2365-2374 Published online on: 07 September 2015
Article
Ursolic acid inhibits the proliferation of human ovarian cancer stem-like cells through epithelial-mesenchymal transition
Jie Zhang, Wenjing Wang, Lin Qian, Qiuwan Zhang, Dongmei Lai, Cong Qi
Pages: 2375-2384 Published online on: 20 August 2015
Article
Expression of RAP1B is associated with poor prognosis and promotes an aggressive phenotype in gastric cancer
Ya Yang, Min Li, Yan Yan, Jia Zhang, Kai Sun, Jing‑Kun Qu, Jian-Sheng Wang, Xiao-Yi Duan
Pages: 2385-2394 Published online on: 01 September 2015
Article
An HCG-rich microenvironment contributes to ovarian cancer cell differentiation into endothelioid cells in a three-dimensional culture system
Min Su, Chao Fan, Sainan Gao, Aiguo Shen, Xiaoying Wang, Yuquan Zhang
Pages: 2395-2402 Published online on: 20 August 2015
Article
Sp1 cooperates with Sp3 to upregulate MALAT1 expression in human hepatocellular carcinoma
Ziling Huang, Lanshan Huang, Siqiao Shen, Jia Li, Huiping Lu, Weijia Mo, Yiwu Dang, Dianzhong Luo, Gang Chen, Zhenbo Feng
Pages: 2403-2412 Published online on: 08 September 2015
Article
Exogenous hydrogen sulfide promotes C6 glioma cell growth through activation of the p38 MAPK/ERK1/2-COX-2 pathways
Yulan Zhen, Wei Zhang, Chujie Liu, Jing He, Yun Lu, Ruixian Guo, Jianqiang Feng, Ying Zhang, Jingfu Chen
Pages: 2413-2422 Published online on: 08 September 2015
Article
Mitogen-activated protein kinase phosphatase 1 is involved in tamoxifen resistance in MCF7 cells
Gang Ma, Yixia Pan, Can Zhou, Ruifang Sun, Jingjing Bai, Peijun Liu, Yu Ren, Jianjun He
Pages: 2423-2430 Published online on: 02 September 2015
Article
Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces cell cycle arrest and apoptosis via the downregulation of Akt in human lung cancer cells
Hyun Sook Lim, Yong Jung Kang, Bokyung Sung, Seon Hee Kim, Min Jeong Kim, Hye Rim Kim, Seong Jin Kim, Yung Hyun Choi, Hyung Ryong Moon, Hae Young Chung, Nam Deuk Kim
Pages: 2431-2438 Published online on: 19 August 2015
Article
Improved sensitivity and specificity for prostate cancer diagnosis based on the urine PCA3/PSA ratio acquired by sequence‑specific RNA capture
Kewen Zheng, Yaling Dou, Linfu He, Hanzhong Li, Zhicai Zhang, Yu Chen, Ali Ye, Wenjing Liu, Lingjun Kong
Pages: 2439-2444 Published online on: 09 September 2015
Article
Suppression of LPS-induced epithelial-mesenchymal transition by aqueous extracts of Prunella vulgaris through inhibition of the NF-κB/Snail signaling pathway and regulation of EMT-related protein expression
In-Hye Cho, Eun Hyang Jang, Darong Hong, Bom Jung, Min-Ju Park, Jong-Ho Kim
Pages: 2445-2450 Published online on: 21 August 2015
Article
ADAM15 targets MMP9 activity to promote lung cancer cell invasion
Dan-Dan Dong, Hui Zhou, Gao Li
Pages: 2451-2460 Published online on: 14 August 2015
Article
Silibinin induces apoptosis through inhibition of the mTOR-GLI1-BCL2 pathway in renal cell carcinoma
Zhenkun Ma, Wei Liu, Jin Zeng, Jiancheng Zhou, Peng Guo, Hongjun Xie, Zhao Yang, Long Zheng, Shan Xu, Xinyang Wang, Luke S. Chang, Dalin He, Lei Li
Pages: 2461-2468 Published online on: 26 August 2015
Article
Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells
Chen Zhang, Yaping Tian, Feiyu Song, Changhao Fu, Bo Han, Yi Wang
Pages: 2469-2476 Published online on: 08 September 2015
Article
Analysis of the differential secretome of nasopharyngeal carcinoma cell lines CNE-2R and CNE-2
Ze-Tan Chen, Ling Li, Ya Guo, Song Qu, Wei Zhao, Hao Chen, Fang Su, Jun Yin, Qi-Yan Mo, Xiao-Dong Zhu
Pages: 2477-2488 Published online on: 08 September 2015
Article
PEITC inhibits human brain glioblastoma GBM 8401 cell migration and invasion through the inhibition of uPA, Rho A, and Ras with inhibition of MMP-2, -7 and -9 gene expression
Yu-Cheng Chou, Meng-Ya Chang, Mei-Jen Wang, Fu-Shun Yu, Hsin-Chung Liu, Tomor Harnod, Chih-Huang Hung, Hsu-Tung Lee, Jing-Gung Chung
Pages: 2489-2496 Published online on: 08 September 2015
Article
CD90 is upregulated in gastric cancer tissues and inhibits gastric cancer cell apoptosis by modulating the expression level of SPARC protein
Guang Chao Zhu, Lu Gao, Junyu He, Yuehua Long, Shan Liao, Haiyun Wang, Xujuan Li, Wei Yi, Zhen Pei, Minghua Wu, Juanjuan Xiang, Shuping Peng, Jian Ma, Ming Zhou, Zhaoyang Zeng, Bo Xiang, Wei Xiong, Ke Tang, Li Cao, Xiaoling Li, Guiyuan Li, Yanhong Zhou
Pages: 2497-2506 Published online on: 01 September 2015
Article
RGS22 inhibits pancreatic adenocarcinoma cell migration through the G12/13 α subunit/F-actin pathway
Yanqiu Hu, Jun Xing, Ling Chen, Ying Zheng, Zuomin Zhou
Pages: 2507-2514 Published online on: 19 August 2015
Article
Overexpression of CIP2A in clear cell renal cell carcinoma promotes cellular epithelial-mesenchymal transition and is associated with poor prognosis
Qizhen Tang, Qifei Wang, Guang Zeng, Quanlin Li, Tao Jiang, Zhiwei Zhang, Wei Zheng, Kenan Wang
Pages: 2515-2522 Published online on: 21 August 2015
Article
Inhibition of cell proliferation and metastasis of human hepatocellular carcinoma by miR-137 is regulated by CDC42
Ming Gao, Liying Liu, Shenglei Li, Xudong Zhang, Zhiwei Chang, Mingzhi Zhang
Pages: 2523-2532 Published online on: 09 September 2015
Article
Induction of apoptosis by an ethanol extract of Poria cocos Wolf. in human leukemia U937 cells
Yung Hyun Choi
Pages: 2533-2540 Published online on: 08 September 2015
Article
Involvement of nuclear receptor RZR/RORγ in melatonin-induced HIF-1α inactivation in SGC-7901 human gastric cancer cells
Ri-Xiong Wang, Hui Liu, Li Xu, Hui Zhang, Rui-Xiang Zhou
Pages: 2541-2546 Published online on: 01 September 2015
Article
N‑acetyl-S-(p-chlorophenylcarbamoyl)cysteine induces mitochondrial-mediated apoptosis and suppresses migration in melanoma cells
Wei Chen, Zhiming Jiang, Xiaoying Zhang, Jianguo Feng, Yutian Ling
Pages: 2547-2556 Published online on: 09 September 2015
Article
Downregulation of VMP1 confers aggressive properties to colorectal cancer
Xian-Zhi Guo, Xiao-Lei Ye, Wei-Zhong Xiao, Xue-Ni Wei, Qing-Hua You, Xiao‑Hang Che, Yan-Jun Cai, Fang Chen, Hao Yuan, Xiao-Jian Liu, Ming-Hua Yu
Pages: 2557-2566 Published online on: 01 September 2015
Article
Anti-CD3 x EGFR bispecific antibody redirects cytokine-induced killer cells to glioblastoma in vitro and in vivo
Pan Ma, Qiang He, Wei Li, Xianliang Li, Huamin Han, Mengmeng Jin, Changzhen Liu, Hua Tao, Juan Ma, Bin Gao
Pages: 2567-2575 Published online on: 28 August 2015
Article
MicroRNA-92a contributes to tumor growth of human hepatocellular carcinoma by targeting FBXW7 Corrigendum in /10.3892/or.2023.8596
Wei Yang, Changwei Dou, Yufeng Wang, Yuli Jia, Chao Li, Xin Zheng, Kangsheng Tu
Pages: 2576-2584 Published online on: 19 August 2015
Article
Integrated analysis of the differential cellular and EBV miRNA expression profiles in microdissected nasopharyngeal carcinoma and non-cancerous nasopharyngeal tissues
Xun-Xun Wan, Hong Yi, Jia-Quan Qu, Qiu-Yan He, Zhi-Qiang Xiao
Pages: 2585-2601 Published online on: 01 September 2015
Article
Hexane extract from Sargassum serratifolium inhibits the cell proliferation and metastatic ability of human glioblastoma U87MG cells
Chang-Won Kang, Min-Seok Park, Nan-Hee Kim, Ji-Hyun Lee, Chul-Woong Oh, Hyeung-Rak Kim, Gun-Do Kim
Pages: 2602-2608 Published online on: 21 August 2015
Article
Cancer predisposing BARD1 mutations affect exon skipping and are associated with overexpression of specific BARD1 isoforms
Magdalena Ratajska, Magdalena Matusiak, Alina Kuzniacka, Bartosz Wasag, Izabela Brozek, Wojciech Biernat, Magdalena Koczkowska, Jaroslaw Debniak, Marcin Sniadecki, Piotr Kozlowski, Katarzyna Klonowska, Maxim Pilyugin, Dariusz Wydra, Geoff Laurent, Janusz Limon, Irmgard Irminger-Finger
Pages: 2609-2617 Published online on: 01 September 2015
Article
Lentiviral-mediated multiple gene transfer to chondrocytes promotes chondrocyte differentiation and bone formation in rabbit bone marrow-derived mesenchymal stem cells
Ping Liu, Liang Sun, Hui Chen, Shui Sun, Dongsheng Zhou, Bo Pang, Jian Wang
Pages: 2618-2626 Published online on: 01 September 2015
Article
Identification of biomarkers with a tumor stage-dependent expression and exploration of the mechanism involved in laryngeal squamous cell carcinoma
Lian Hui, Ning Yang, Huijun Yang, Xing Guo, Xuejun Jang
Pages: 2627-2635 Published online on: 27 August 2015
Article
Expression and promoter methylation of Wnt inhibitory factor-1 in the development of oral submucous fibrosis
Shanghui Zhou, Ling Chen, Mubarak Mashrah, Yun Zhu, Zhijing He, Yuhua Hu, Tingxiu Xiang, Zhigang Yao, Feng Guo, Chenping Zhang
Pages: 2636-2642 Published online on: 09 September 2015
Article
GdCl3 suppresses the malignant potential of hepatocellular carcinoma by inhibiting the expression of CD206 in tumor‑associated macrophages
Fangyu Zhu, Xiangnan Li, Yong Jiang, Haoran Zhu, Haolong Zhang, Chengyao Zhang, Yu Zhao, Fang Luo
Pages: 2643-2655 Published online on: 09 September 2015
Article
Hyperthermia induces apoptosis by targeting Survivin in esophageal cancer
Sida Qin, Chongwen Xu, Shuo Li, Xifang Wang, Xin Sun, Peili Wang, Boxiang Zhang, Hong Ren
Pages: 2656-2664 Published online on: 08 September 2015
Article
miR-1291 targets mucin 1 inhibiting cell proliferation and invasion to promote cell apoptosis in esophageal squamous cell carcinoma
Hailan Luo, Wentao Guo, Fei Wang, Yanjie You, Jianguo Wang, Xudong Chen, Jihong Wang, Yuanyuan Wang, Yuwen Du, Xiaonan Chen, Changgui Xue, Guohua Song, Fuqing Wang
Pages: 2665-2673 Published online on: 19 August 2015
Article
Farnesoid X receptor signal is involved in deoxycholic acid-induced intestinal metaplasia of normal human gastric epithelial cells
Shu Li, Xin Chen, Lu Zhou, Bang-Mao Wang
Pages: 2674-2682 Published online on: 19 August 2015
Article
Fibroblast growth factor 19 is correlated with an unfavorable prognosis and promotes progression by activating fibroblast growth factor receptor 4 in advanced-stage serous ovarian cancer
Lingling Hu, Lanxiang Cong
Pages: 2683-2691 Published online on: 20 August 2015
Article
Genistein enhances TRAIL-induced cancer cell death via inactivation of autophagic flux
Uddin Md. Nazim, Sang-Youel Park
Pages: 2692-2698 Published online on: 07 September 2015
Article
New mouse xenograft model modulated by tumor-associated fibroblasts for human multi-drug resistance in cancer
Yan Ma, Zhiqiang Lin, John K. Fallon, Qiang Zhao, Dan Liu, Yongjun Wang, Feng Liu
Pages: 2699-2705 Published online on: 09 September 2015
Article
MicroRNA-1908 is upregulated in human osteosarcoma and regulates cell proliferation and migration by repressing PTEN expression
Hongmou Yuan, Yanjun Gao
Pages: 2706-2714 Published online on: 01 September 2015
Article
Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells
Dong Shen, Cheng-Cheng Guo, Jing Wang, Zhi-Kun Qiu, Ke Sai, Qun-Ying Yang, Yin-Sheng Chen, Fu-Rong Chen, Jie Wang, Lawrence Panasci, Zhong-Ping Chen
Pages: 2715-2721 Published online on: 27 August 2015
Article
SET and MYND domain-containing protein 3 is overexpressed in human glioma and contributes to tumorigenicity
Bin Dai, Weiqing Wan, Peng Zhang, Yisong Zhang, Changcun Pan, Guolu Meng, Xinru Xiao, Zhen Wu, Wang Jia, Junting Zhang, Liwei Zhang
Pages: 2722-2730 Published online on: 01 September 2015
Article
IM-412 inhibits the invasion of human breast carcinoma cells by blocking FGFR-mediated signaling
Seung-Youn Jung, Jae Youn Yi, Mi-Hyoung Kim, Kyung-Hee Song, Seong-Mook Kang, Jiyeon Ahn, Sang-Gu Hwang, Ky-Youb Nam, Jie-Young Song
Pages: 2731-2737 Published online on: 08 September 2015
Article
Sequential gemcitabine and tamoxifen treatment enhances apoptosis and blocks transformation in bladder cancer cells
Hisashi Takeuchi, Chinedu O. Mmeje, Goodwin G. Jinesh, Rikiya Taoka, Ashish M. Kamat
Pages: 2738-2744 Published online on: 21 August 2015
Article
Hypoxia-induced fibroblast growth factor 11 stimulates capillary-like endothelial tube formation
Jimin Yang, Woo Jean Kim, Hyoung Oh Jun, Eun Ju Lee, Kyeong Won Lee, Jae-Yeon Jeong, Sae-Won Lee
Pages: 2745-2751 Published online on: 24 August 2015
Article
Time-dependent release of extracellular vesicle subpopulations in tumor CABA I cells
Ilaria Giusti, Marianna Di Francesco, Laura Cantone, Sandra D'Ascenzo, Valentina Bollati, Gaspare Carta, Vincenza Dolo
Pages: 2752-2759 Published online on: 12 August 2015
Article
The significance of the altered expression of lysophosphatidic acid receptors, autotaxin and phospholipase A2 as the potential biomarkers in type 1 endometrial cancer biology
Tomasz Wasniewski, Izabela Woclawek-Potocka, Dorota Boruszewska, Ilona Kowalczyk-Zieba, Emilia Sinderewicz, Katarzyna Grycmacher
Pages: 2760-2767 Published online on: 20 August 2015
Article
Isolation and characterization of circulating micro(nano)vesicles in the plasma of colorectal cancer patients and their interactions with tumor cells
Małgorzata Stec, Monika Baj-Krzyworzeka, Jarosław Baran, Kazimierz Węglarczyk, Maria Zembala, Jakub Barbasz, Antoni Szczepanik, Marek Zembala
Pages: 2768-2775 Published online on: 26 August 2015
Article
HAX-1 inhibits apoptosis in prostate cancer through the suppression of caspase-9 activation
Jiliang Yan, Chunyan Ma, Jian Cheng, Zhengguo Li, Chao Liu
Pages: 2776-2781 Published online on: 13 August 2015
Article
Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of PI3K/Akt signaling pathway
Hai Jin, Fan Qiao, Yan Wang, Yongdong Xu, Yan Shang
Pages: 2782-2789 Published online on: 08 September 2015
Article
Cytoprotective effects of ferritin on doxorubicin-induced breast cancer cell death
Benjaporn Buranrat, James R. Connor
Pages: 2790-2796 Published online on: 08 September 2015
Article
