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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

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Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

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Journal Cover
September-2022 Volume 26 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Effects of boric acid and potassium metaborate on cytokine levels and redox stress parameters in a wound model infected with methicillin‑resistant Staphylococcus aureus

Demet Celebi, Ali Taghizadehghalehjoughi, Sumeyye Baser, Sidika Genc, Aysegul Yilmaz, Yesim Yeni, Fatma Yesilyurt, Serkan Yildirim, Ismail Bolat, Saban Kordali, Ferah Yilmaz, Ahmet Hacimuftuoglu, Ozgur Celebi, Denisa Margina, George Mihai Nitulescu, Demetrios A. Spandidos, Aristidis Tsatsakis
Article Number: 294
Published online on: 02 August 2022

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Novel splice‑site variants c.393G>A, c.278_2A>G in exon 2 and Q705K variant in exon 3 of NLRP3 gene are associated with bipolar I disorder

Kuyaş Heki̇mler Öztürk, Güli̇n Özdamar Ünal
Article Number: 293
Published online on: 02 August 2022

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Inhibition of miR‑98‑5p promotes high glucose‑induced suppression of preosteoblast proliferation and differentiation via the activation of the PI3K/AKT/GSK3β signaling pathway by targeting BMP2

Feng Zheng, Fucai Zhang, Furong Wang
Article Number: 292
Published online on: 29 July 2022

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Correlation between serum immunoglobulin levels and retinal structure in patients with newly diagnosed Vogt‑Koyanagi‑Harada disease

Zhijian Jiang, Nan Zhang, Huiying Ji, Maoli Zhu, Min Zhou, Jianhong Dong
Article Number: 291
Published online on: 29 July 2022

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Knockdown of hsa_circ_0005699 attenuates inflammation and apoptosis induced by ox-LDL in human umbilical vein endothelial cells through regulation of the miR-450b-5p/NFKB1 axis

Tao Chen, Lei Li, Bo Ye, Weiqing Chen, Guofu Zheng, Hailiang Xie, Yi Guo
Article Number: 290
Published online on: 28 July 2022

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Article Open Access

Macrophage migration inhibitory factor takes part in the lumbar ligamentum flavum hypertrophy

Qi-Lin Lu, Zi-Xuan Zheng, Yu-Hui Ye, Jiang-Yun Lu, Yu-Qi Zhong, Chao Sun, Cheng-Jie Xiong, Gong-Xu Yang, Feng Xu
Article Number: 289
Published online on: 27 July 2022

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Retraction Open Access

[Retracted] MicroRNA‑744 inhibits tumor cell proliferation and invasion of gastric cancer via targeting brain‑derived neurotrophic factor

Ai-Jun Xu, Li-Na Fu, Hua-Xing Wu, Xiao-Li Yao, Rui Meng
Article Number: 288
Published online on: 27 July 2022

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Article Open Access

Characterization of plasma exosomal microRNAs in responding to radiotherapy of human esophageal squamous cell carcinoma

Nan Miao, Wenjie Cai, Sijia Ding, Yajuan Liu, Wanhua Chen, Tao Sun
Article Number: 287
Published online on: 27 July 2022

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Decreased RNA‑binding protein IGF2BP2 downregulates NT5DC2, which suppresses cell proliferation, and induces cell cycle arrest and apoptosis in diffuse large B‑cell lymphoma cells by regulating the p53 signaling pathway Corrigendum in /10.3892/mmr.2023.12954

Yuying Cui, Yu Wen, Chao Lv, Dongmei Zhao, Yu Yang, Hongbin Qiu, Chennan Wang
Article Number: 286
Published online on: 27 July 2022

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Article Open Access

Reducing VEGFB expression regulates the balance of glucose and lipid metabolism in mice via VEGFR1

Xu Luo, Rong-Rong Li, Yu-Qi Li, Han-Pu Yu, Hai-Ning Yu, Wen-Guo Jiang, Ya-Na Li
Article Number: 285
Published online on: 26 July 2022

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Interference of PTK6/GAB1 signaling inhibits cell proliferation, invasion, and migration of cervical cancer cells

Juan Li, Nan Yang, Xiaolei Tian, Linglong Ouyang, Man Jiang, Shufang Zhang
Article Number: 284
Published online on: 26 July 2022

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Correction Open Access

[Corrigendum] MicroRNA‑335 is downregulated in bladder cancer and inhibits cell growth, migration and invasion via targeting ROCK1

Deyao Wu, Xiaobing Niu, Huixing Pan, Yunfeng Zhou, Ping Qu, Jian Zhou
Article Number: 283
Published online on: 26 July 2022

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A novel de novo heterozygous variant of the KCNQ2 gene: Contribution to early‑onset epileptic encephalopathy in a female infant

Hai-Feng Liu, Ting-Yun Yuan, Jia-Wu Yang, Feng Li, Fan Wang, Hong-Min Fu
Article Number: 282
Published online on: 19 July 2022

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Retraction Open Access

[Retracted] Upregulation of microRNA‑25‑3p inhibits proliferation, migration and invasion of osteosarcoma cells in vitro by directly targeting SOX4

Xiaolin Wu, Hongzhong Zhou, Bin Yue, Maohua Li, Fengxia Liu, Chensheng Qiu, Bohua Chen, Xuexiao Ma
Article Number: 281
Published online on: 19 July 2022

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Review Open Access

Functions and mechanisms of N6‑methyladenosine in prostate cancer (Review)

Hongyuan Wan, Yanyan Feng, Junjie Wu, Lijie Zhu, Yuanyuan Mi
Article Number: 280
Published online on: 19 July 2022

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Article Open Access

Adipose‑derived mesenchymal stem cell‑derived HCAR1 regulates immune response in the attenuation of sepsis

Hongyan Wang, Pengfei Xuan, Hongjun Tian, Xinyu Hao, Jingping Yang, Xiyuan Xu, Lixia Qiao
Article Number: 279
Published online on: 15 July 2022

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Protective effect of 17S‑epoxy‑docosapentaenoic acid against dextran sulfate sodium induced ulcerative colitis in BALB/c mice.

Lifang Wang, Hack Sun Choi, Yan Su, Binna Lee, Jong Hyun Choi, Sun-Hee Jang, Yong-Suk Jang, Jeong-Woo Seo
Article Number: 278
Published online on: 15 July 2022

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Article

MCP‑1/CCR2 axis inhibits the chondrogenic differentiation of human nucleus pulposus mesenchymal stem cells

Xuancheng Ou, Tianyong Wen, Jinwei Ying, Qing He, Anwu Xuan, Dike Ruan
Article Number: 277
Published online on: 15 July 2022

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Retraction Open Access

[Retracted] MicroRNA‑643 regulates the expression of ZEB1 and inhibits tumorigenesis in osteosarcoma

Huan Wang, Danmou Xing, Dong Ren, Wei Feng, Yan Chen, Zhiming Zhao, Zhihong Xiao, Zhengren Peng
Article Number: 276
Published online on: 11 July 2022

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ANP32E contributes to gastric cancer progression via NUF2 upregulation

Xiaowen Zhu, Yumin Zou, Tong Wu, Jian Ni, Qingyun Tan, Qingdong Wang, Meijia Zhang
Article Number: 275
Published online on: 06 July 2022

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Retraction Open Access

[Retracted] microRNA‑145 inhibits osteosarcoma cell proliferation and invasion by targeting ROCK1

Pengfei Lei, Jie Xie, Long Wang, Xucheng Yang, Zixun Dai, Yihe Hu
Article Number: 274
Published online on: 04 July 2022

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Journal Cover
September-2026 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chronic kidney disease‑associated encephalopathy: Clinical features, pathomechanisms and emerging therapeutic strategies (Review)

Nanling Zeng, Ling Jiang, Yang Zhang, Jian Liu, Qiong Zhang, Lishang Liao, Qiongdan Hu
Article Number: 259
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways

Yun Lin, Weiming Chen, Zhihong Wang, Pengwei Cai
Article Number: 258
Published online on: 20 July 2026

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Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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Article Open Access

PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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Review Open Access

From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Article

Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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Review Open Access

A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Review Open Access

Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Article Open Access

Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Article Open Access

Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Article Open Access

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Article Open Access

Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 34 Issue 4

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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Article Open Access

STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Review Open Access

Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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