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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2020 Volume 46 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Towards effective COVID‑19 vaccines: Updates, perspectives and challenges (Review)

Daniela Calina, Anca Oana Docea, Demetrios Petrakis, Alex M. Egorov, Aydar A. Ishmukhametov, Alexsandr G. Gabibov, Michael I. Shtilman, Ronald Kostoff, Félix Carvalho, Marco Vinceti, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 3-16
Published online on: 06 May 2020

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Review Open Access

Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review)

Anatoly V. Skalny, Lothar Rink, Olga P. Ajsuvakova, Michael Aschner, Viktor A. Gritsenko, Svetlana I. Alekseenko, Andrey A. Svistunov, Demetrios Petrakis, Demetrios A. Spandidos, Jan Aaseth, Aristidis Tsatsakis, Alexey A. Tinkov
Pages: 17-26
Published online on: 14 April 2020

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Review Open Access

Large intestine embryogenesis: Molecular pathways and related disorders (Review)

Antonios Kostouros, Ioannis Koliarakis, Konstantinos Natsis, Demetrios A. Spandidos, Aristidis Tsatsakis, John Tsiaoussis
Pages: 27-57
Published online on: 21 April 2020

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Article Open Access

HIKESHI silencing can enhance mild hyperthermia sensitivity in human oral squamous cell carcinoma HSC‑3 cells

Yoshiaki Tabuchi, Keita Maekawa, Misako Torigoe, Yukihiro Furusawa, Tetsushi Hirano, Satsuki Minagawa, Tatsuya Yunoki, Atsushi Hayashi
Pages: 58-66
Published online on: 28 April 2020

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Article Open Access

Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generation

Ying‑Hui Kong, Su‑Ping Xu
Pages: 67-82
Published online on: 24 April 2020

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Article Open Access

Emerging roles of let‑7d in attenuating pulmonary arterial hypertension via suppression of pulmonary artery endothelial cell autophagy and endothelin synthesis through ATG16L1 downregulation

Minghui Ou, Xia Li, Shichao Cui, Shibo Zhao, Jie Tu
Pages: 83-96
Published online on: 07 April 2020

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Article Open Access

Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p

Yinghao Cao, Wenfei Lv, Wan Ding, Jun Li
Pages: 97-106
Published online on: 14 April 2020

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Article Open Access

CircSAMD4A regulates cell progression and epithelial‑mesenchymal transition by sponging miR‑342‑3p via the regulation of FZD7 expression in osteosarcoma

Chuhai Xie, Binwei Chen, Boyi Wu, Jianhong Guo, Yulong Shi, Yanming Cao
Pages: 107-118
Published online on: 22 April 2020

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Article Open Access

Long non‑coding RNA PRNCR1 exerts oncogenic effects in tongue squamous cell carcinoma in vitro and in vivo by sponging microRNA‑944 and thereby increasing HOXB5 expression Retraction in /10.3892/ijmm.2022.5183

Cong Lin, Yanan Zou, Ruijing Li, Daofeng Liu
Pages: 119-130
Published online on: 16 April 2020

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Article Open Access

MicroRNA‑17 contributes to the suppression of the inflammatory response in lipopolysaccharide‑induced acute lung injury in mice via targeting the toll‑like receptor 4/nuclear factor‑κB pathway

Shan Fu
Pages: 131-140
Published online on: 12 May 2020

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Article Open Access

TGF‑β1 induces CREB1‑mediated miR‑1290 upregulation to antagonize lung fibrosis via Napsin A

Shuhong Guan, Yudi Wu, Qiudi Zhang, Jun Zhou
Pages: 141-148
Published online on: 03 April 2020

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Article Open Access

NED416, a novel synthetic Sirt1 activator, promotes cutaneous wound healing via the MAPK/Rho pathway

Hussain Mustatab Wahedi, Jae Khyung Chae, Lalita Subedi, Min Cheol Kang, Hyunkyung Cho, Sanghee Kim, Sun Yeou Kim
Pages: 149-158
Published online on: 03 April 2020

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Article Open Access

LncRNA BCAR4 promotes liver cancer progression by upregulating ANAPC11 expression through sponging miR‑1261

Yu Zhang, Hongyan Zhou
Pages: 159-166
Published online on: 22 April 2020

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Article Open Access

Osteocyte TGFβ1‑Smad2/3 is positively associated with bone turnover parameters in subchondral bone of advanced osteoarthritis

Guangming Dai, Haozhuo Xiao, Junyi Liao, Nian Zhou, Chen Zhao, Wei Xu, Wenjuan Xu, Xi Liang, Wei Huang
Pages: 167-178
Published online on: 14 April 2020

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Article Open Access

Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts

Jianghong Gao, Xinmei Li, Liping Gao, Haiyan Chen, Bashayer H. Baras, Xiaojing Liu, Hao Liu, Ayesha Rana, Meili Gao, Jianping Ruan
Pages: 179-190
Published online on: 12 May 2020

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Article Open Access

The JAK2/STAT3 pathway inhibitor, AG490, suppresses the abnormal behavior of keloid fibroblasts in vitro

Ying Zhou, Yuexin Sun, Wenjun Hou, Liwen Ma, Yue Tao, Dan Li, Cui Xu, Jun Bao, Weixin Fan
Pages: 191-200
Published online on: 29 April 2020

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Article Open Access

XPD inhibits cell growth and invasion and enhances chemosensitivity in esophageal squamous cell carcinoma by regulating the PI3K/AKT signaling pathway

Jie Jian, Shuang Li, Li‑Zhen Liu, Li Zhen, Ling Yao, Li‑Hong Gan, Ya‑Qing Huang, Nian Fang
Pages: 201-210
Published online on: 04 May 2020

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Article Open Access

LRP6 is involved in the proliferation, migration and invasion of trophoblast cells via miR‑346

Lu Zhang, Huihui Li, Mingbao Li, Wenxia Zhang, Zhou Yang, Shuquan Zhang
Pages: 211-223
Published online on: 08 April 2020

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Article Open Access

Genome‑wide DNA methylation regulation analysis of long non‑coding RNAs in glioblastoma

Jianghuai Ji, Lei Zhao, Xiaoxiao Zhao, Qianpeng Li, Yi An, Li Li, Dongguo Li
Pages: 224-238
Published online on: 15 April 2020

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Article Open Access

Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway Retraction in /10.3892/ijmm.2024.5404

Yang Zhou, Hongyu Lian, Kexin Liu, Deli Wang, Xuelian Xiu, Zhang Sun
Pages: 239-251
Published online on: 06 May 2020

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Article Open Access

A risk score system based on DNA methylation levels and a nomogram survival model for lung squamous cell carcinoma

Ming Zhang, Libing Sun, Yi Ru, Shasha Zhang, Junjun Miao, Pengda Guo, Jinghuan Lv, Feng Guo, Biao Liu
Pages: 252-264
Published online on: 27 April 2020

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Article Open Access

Mechanism of Notch1‑saRNA‑1480 reversing androgen sensitivity in human metastatic castration‑resistant prostate cancer

Libin Ma, Kang Jiang, Peiwu Jiang, Han He, Kean Chen, Jia Shao, Gang Deng
Pages: 265-279
Published online on: 08 May 2020

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Article Open Access

Downregulation of c‑FLIP and upregulation of DR‑5 by cantharidin sensitizes TRAIL‑mediated apoptosis in prostate cancer cells via autophagy flux

Uddin Md Nazim, Honghua Yin, Sang‑Youel Park
Pages: 280-288
Published online on: 06 April 2020

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Article Open Access

Long non-coding RNA PART1 promotes intervertebral disc degeneration through regulating the miR‑93/MMP2 pathway in nucleus pulposus cells

Dongmei Gao, Long Hao, Zilong Zhao
Pages: 289-299
Published online on: 16 April 2020

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Article Open Access

EOFAZ inhibits endothelial‑to‑mesenchymal transition through downregulation of KLF4

Yanyan Zhang, Chen Li, Yongpan Huang, Shuang Zhao, Yini Xu, Yan Chen, Feng Jiang, Ling Tao, Xiangchun Shen
Pages: 300-310
Published online on: 09 April 2020

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Article Open Access

Cyclopamine functions as a suppressor of benign prostatic hyperplasia by inhibiting epithelial and stromal cell proliferation via suppression of the Hedgehog signaling pathway

Yi‑Feng Yuan, Wen‑Xiong Zhu, Tao Liu, Ju‑Qiao He, Qing Zhou, Xing Zhou, Xi Zhang, Jing Yang
Pages: 311-319
Published online on: 08 April 2020

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Article Open Access

Transient receptor potential canonical 1 channel mediates the mechanical stress‑induced epithelial‑mesenchymal transition of human bronchial epithelial (16HBE) cells

Jing Wang, Ye He, Gang Yang, Na Li, Minchao Li, Min Zhang
Pages: 320-330
Published online on: 07 April 2020

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Article Open Access

Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation

Rui Zhang, Liming Xu, Xiaoxia An, Xinbing Sui, Shuang Lin
Pages: 331-339
Published online on: 13 April 2020

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Article Open Access

Astragaloside IV protects retinal pigment epithelial cells from apoptosis by upregulating miR‑128 expression in diabetic rats

Tao Wang, Zhongwei Zhang, Caiping Song, Lei Sun, Xinli Sui, Qun Qu, Jing Liu
Pages: 340-350
Published online on: 23 April 2020

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Article Open Access

Spirulina protein promotes skin wound repair in a mouse model of full-thickness dermal excisional wound

Ping Liu, Jeong‑Wook Choi, Min‑Kyeong Lee, Youn Hee Choi, Taek‑Jeong Nam
Pages: 351-359
Published online on: 08 April 2020

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Article Open Access

MicroRNA‑1 regulates the development of osteoarthritis in a Col2a1‑Cre‑ERT2/GFPfl/fl‑RFP‑miR‑1 mouse model of osteoarthritis through the downregulation of Indian hedgehog expression

Xianda Che, Taoyu Chen, Lei Wei, Xiaodong Gu, Yangyang Gao, Shufen Liang, Penghua Li, Dongping Shi, Bin Liang, Chunfang Wang, Pengcui Li
Pages: 360-370
Published online on: 12 May 2020

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Article Open Access

Proteomic landscape of human coronary artery atherosclerosis

Yaqing Zhou, Jinxia Yuan, Yinwen Fan, Fenghui An, Jiaxin Chen, Yongjie Zhang, Jianliang Jin, Mufeng Gu, Zhiyuan Mao, Haijian Sun, Qiaowei Jia, Chenhui Zhao, Mingyue Ji, Jing Zhang, Guangxu Xu, Enzhi Jia
Pages: 371-383
Published online on: 12 May 2020

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Article Open Access

miR‑199a decreases Neuritin expression involved in the development of Alzheimer's disease in APP/PS1 mice

Dandan Song, Guoxiang Li, Yu Hong, Pan Zhang, Jingling Zhu, Lei Yang, Jin Huang
Pages: 384-396
Published online on: 12 May 2020

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Article

MicroRNA‑383‑5p inhibits the proliferation and promotes the apoptosis of gastric cancer cells by targeting cancerous inhibitor of PP2A

Xinxin Li, Jinpeng Yuan, Qiangjian Cao, Aosi Xie, Juntian Chen
Pages: 397-405
Published online on: 12 May 2020

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Article

Downregulation of miR‑141 deactivates hepatic stellate cells by targeting the PTEN/AKT/mTOR pathway

Haijun Liang, Xinwei Wang, Changyun Si, Yuxiu Duan, Baoxin Chen, Haixia Liang, Daokun Yang
Pages: 406-414
Published online on: 15 April 2020

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Article

Phorbol myristate acetate induces cellular senescence in rat microglia in vitro

Dan Cao, Xiao-Hong Li, Xiao-Guang Luo, Hong-Mei Yu, Li-Shu Wan, Ling Wei, Yan Ren
Pages: 415-426
Published online on: 23 April 2020

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Article

Promotion of liver regeneration and anti‑fibrotic effects of the TGF‑β receptor kinase inhibitor galunisertib in CCl4‑treated mice

Atsutaka Masuda, Toru Nakamura, Mitsuhiko Abe, Hideki  Iwamoto, Takahiko Sakaue, Toshimitsu Tanaka, Hiroyuki  Suzuki, Hironori Koga, Takuji Torimura
Pages: 427-438
Published online on: 05 May 2020

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Article

Propofol induces apoptosis by activating caspases and the MAPK pathways, and inhibiting the Akt pathway in TM3 mouse Leydig stem/progenitor cells

Fu‑Chi Kang, Yun‑Chia Chen, Shu‑Chun Wang, Edmund Cheung So, Bu‑Miin Huang
Pages: 439-448
Published online on: 21 April 2020

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Article Open Access

Cinnamaldehyde protects against oxidative stress and inhibits the TNF‑α‑induced inflammatory response in human umbilical vein endothelial cells

Nam‑Yi Kim, Nguyet‑Tran Trinh, Sang‑Gun Ahn, Soo‑A Kim
Pages: 449-457
Published online on: 16 April 2020

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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Review Open Access

mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Article Open Access

Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Review Open Access

Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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Review Open Access

The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Review Open Access

Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Review Open Access

Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Review Open Access

Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Review Open Access

Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Review Open Access

Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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May-2026 Volume 57 Issue 5

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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