Journal Articles
Review
Towards effective COVID‑19 vaccines: Updates, perspectives and challenges (Review)
Daniela Calina, Anca Oana Docea, Demetrios Petrakis, Alex M. Egorov, Aydar A. Ishmukhametov, Alexsandr G. Gabibov, Michael I. Shtilman, Ronald Kostoff, Félix Carvalho, Marco Vinceti, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 3-16 Published online on: 06 May 2020
Review
Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review)
Anatoly V. Skalny, Lothar Rink, Olga P. Ajsuvakova, Michael Aschner, Viktor A. Gritsenko, Svetlana I. Alekseenko, Andrey A. Svistunov, Demetrios Petrakis, Demetrios A. Spandidos, Jan Aaseth, Aristidis Tsatsakis, Alexey A. Tinkov
Pages: 17-26 Published online on: 14 April 2020
Review
Large intestine embryogenesis: Molecular pathways and related disorders (Review)
Antonios Kostouros, Ioannis Koliarakis, Konstantinos Natsis, Demetrios A. Spandidos, Aristidis Tsatsakis, John Tsiaoussis
Pages: 27-57 Published online on: 21 April 2020
Article
HIKESHI silencing can enhance mild hyperthermia sensitivity in human oral squamous cell carcinoma HSC‑3 cells
Yoshiaki Tabuchi, Keita Maekawa, Misako Torigoe, Yukihiro Furusawa, Tetsushi Hirano, Satsuki Minagawa, Tatsuya Yunoki, Atsushi Hayashi
Pages: 58-66 Published online on: 28 April 2020
Article
Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generation
Ying‑Hui Kong, Su‑Ping Xu
Pages: 67-82 Published online on: 24 April 2020
Article
Emerging roles of let‑7d in attenuating pulmonary arterial hypertension via suppression of pulmonary artery endothelial cell autophagy and endothelin synthesis through ATG16L1 downregulation
Minghui Ou, Xia Li, Shichao Cui, Shibo Zhao, Jie Tu
Pages: 83-96 Published online on: 07 April 2020
Article
Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p
Yinghao Cao, Wenfei Lv, Wan Ding, Jun Li
Pages: 97-106 Published online on: 14 April 2020
Article
CircSAMD4A regulates cell progression and epithelial‑mesenchymal transition by sponging miR‑342‑3p via the regulation of FZD7 expression in osteosarcoma
Chuhai Xie, Binwei Chen, Boyi Wu, Jianhong Guo, Yulong Shi, Yanming Cao
Pages: 107-118 Published online on: 22 April 2020
Article
Long non‑coding RNA PRNCR1 exerts oncogenic effects in tongue squamous cell carcinoma in vitro and in vivo by sponging microRNA‑944 and thereby increasing HOXB5 expression Retraction in /10.3892/ijmm.2022.5183
Cong Lin, Yanan Zou, Ruijing Li, Daofeng Liu
Pages: 119-130 Published online on: 16 April 2020
Article
MicroRNA‑17 contributes to the suppression of the inflammatory response in lipopolysaccharide‑induced acute lung injury in mice via targeting the toll‑like receptor 4/nuclear factor‑κB pathway
Shan Fu
Pages: 131-140 Published online on: 12 May 2020
Article
TGF‑β1 induces CREB1‑mediated miR‑1290 upregulation to antagonize lung fibrosis via Napsin A
Shuhong Guan, Yudi Wu, Qiudi Zhang, Jun Zhou
Pages: 141-148 Published online on: 03 April 2020
Article
NED416, a novel synthetic Sirt1 activator, promotes cutaneous wound healing via the MAPK/Rho pathway
Hussain Mustatab Wahedi, Jae Khyung Chae, Lalita Subedi, Min Cheol Kang, Hyunkyung Cho, Sanghee Kim, Sun Yeou Kim
Pages: 149-158 Published online on: 03 April 2020
Article
LncRNA BCAR4 promotes liver cancer progression by upregulating ANAPC11 expression through sponging miR‑1261
Yu Zhang, Hongyan Zhou
Pages: 159-166 Published online on: 22 April 2020
Article
Osteocyte TGFβ1‑Smad2/3 is positively associated with bone turnover parameters in subchondral bone of advanced osteoarthritis
Guangming Dai, Haozhuo Xiao, Junyi Liao, Nian Zhou, Chen Zhao, Wei Xu, Wenjuan Xu, Xi Liang, Wei Huang
Pages: 167-178 Published online on: 14 April 2020
Article
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts
Jianghong Gao, Xinmei Li, Liping Gao, Haiyan Chen, Bashayer H. Baras, Xiaojing Liu, Hao Liu, Ayesha Rana, Meili Gao, Jianping Ruan
Pages: 179-190 Published online on: 12 May 2020
Article
The JAK2/STAT3 pathway inhibitor, AG490, suppresses the abnormal behavior of keloid fibroblasts in vitro
Ying Zhou, Yuexin Sun, Wenjun Hou, Liwen Ma, Yue Tao, Dan Li, Cui Xu, Jun Bao, Weixin Fan
Pages: 191-200 Published online on: 29 April 2020
Article
XPD inhibits cell growth and invasion and enhances chemosensitivity in esophageal squamous cell carcinoma by regulating the PI3K/AKT signaling pathway
Jie Jian, Shuang Li, Li‑Zhen Liu, Li Zhen, Ling Yao, Li‑Hong Gan, Ya‑Qing Huang, Nian Fang
Pages: 201-210 Published online on: 04 May 2020
Article
LRP6 is involved in the proliferation, migration and invasion of trophoblast cells via miR‑346
Lu Zhang, Huihui Li, Mingbao Li, Wenxia Zhang, Zhou Yang, Shuquan Zhang
Pages: 211-223 Published online on: 08 April 2020
Article
Genome‑wide DNA methylation regulation analysis of long non‑coding RNAs in glioblastoma
Jianghuai Ji, Lei Zhao, Xiaoxiao Zhao, Qianpeng Li, Yi An, Li Li, Dongguo Li
Pages: 224-238 Published online on: 15 April 2020
Article
Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway
Yang Zhou, Hongyu Lian, Kexin Liu, Deli Wang, Xuelian Xiu, Zhang Sun
Pages: 239-251 Published online on: 06 May 2020
Article
A risk score system based on DNA methylation levels and a nomogram survival model for lung squamous cell carcinoma
Ming Zhang, Libing Sun, Yi Ru, Shasha Zhang, Junjun Miao, Pengda Guo, Jinghuan Lv, Feng Guo, Biao Liu
Pages: 252-264 Published online on: 27 April 2020
Article
Mechanism of Notch1‑saRNA‑1480 reversing androgen sensitivity in human metastatic castration‑resistant prostate cancer
Libin Ma, Kang Jiang, Peiwu Jiang, Han He, Kean Chen, Jia Shao, Gang Deng
Pages: 265-279 Published online on: 08 May 2020
Article
Downregulation of c‑FLIP and upregulation of DR‑5 by cantharidin sensitizes TRAIL‑mediated apoptosis in prostate cancer cells via autophagy flux
Uddin Md Nazim, Honghua Yin, Sang‑Youel Park
Pages: 280-288 Published online on: 06 April 2020
Article
Long non-coding RNA PART1 promotes intervertebral disc degeneration through regulating the miR‑93/MMP2 pathway in nucleus pulposus cells
Dongmei Gao, Long Hao, Zilong Zhao
Pages: 289-299 Published online on: 16 April 2020
Article
EOFAZ inhibits endothelial‑to‑mesenchymal transition through downregulation of KLF4
Yanyan Zhang, Chen Li, Yongpan Huang, Shuang Zhao, Yini Xu, Yan Chen, Feng Jiang, Ling Tao, Xiangchun Shen
Pages: 300-310 Published online on: 09 April 2020
Article
Cyclopamine functions as a suppressor of benign prostatic hyperplasia by inhibiting epithelial and stromal cell proliferation via suppression of the Hedgehog signaling pathway
Yi‑Feng Yuan, Wen‑Xiong Zhu, Tao Liu, Ju‑Qiao He, Qing Zhou, Xing Zhou, Xi Zhang, Jing Yang
Pages: 311-319 Published online on: 08 April 2020
Article
Transient receptor potential canonical 1 channel mediates the mechanical stress‑induced epithelial‑mesenchymal transition of human bronchial epithelial (16HBE) cells
Jing Wang, Ye He, Gang Yang, Na Li, Minchao Li, Min Zhang
Pages: 320-330 Published online on: 07 April 2020
Article
Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation
Rui Zhang, Liming Xu, Xiaoxia An, Xinbing Sui, Shuang Lin
Pages: 331-339 Published online on: 13 April 2020
Article
Astragaloside IV protects retinal pigment epithelial cells from apoptosis by upregulating miR‑128 expression in diabetic rats
Tao Wang, Zhongwei Zhang, Caiping Song, Lei Sun, Xinli Sui, Qun Qu, Jing Liu
Pages: 340-350 Published online on: 23 April 2020
Article
Spirulina protein promotes skin wound repair in a mouse model of full-thickness dermal excisional wound
Ping Liu, Jeong‑Wook Choi, Min‑Kyeong Lee, Youn Hee Choi, Taek‑Jeong Nam
Pages: 351-359 Published online on: 08 April 2020
Article
MicroRNA‑1 regulates the development of osteoarthritis in a Col2a1‑Cre‑ERT2/GFPfl/fl‑RFP‑miR‑1 mouse model of osteoarthritis through the downregulation of Indian hedgehog expression
Xianda Che, Taoyu Chen, Lei Wei, Xiaodong Gu, Yangyang Gao, Shufen Liang, Penghua Li, Dongping Shi, Bin Liang, Chunfang Wang, Pengcui Li
Pages: 360-370 Published online on: 12 May 2020
Article
Proteomic landscape of human coronary artery atherosclerosis
Yaqing Zhou, Jinxia Yuan, Yinwen Fan, Fenghui An, Jiaxin Chen, Yongjie Zhang, Jianliang Jin, Mufeng Gu, Zhiyuan Mao, Haijian Sun, Qiaowei Jia, Chenhui Zhao, Mingyue Ji, Jing Zhang, Guangxu Xu, Enzhi Jia
Pages: 371-383 Published online on: 12 May 2020
Article
miR‑199a decreases Neuritin expression involved in the development of Alzheimer's disease in APP/PS1 mice
Dandan Song, Guoxiang Li, Yu Hong, Pan Zhang, Jingling Zhu, Lei Yang, Jin Huang
Pages: 384-396 Published online on: 12 May 2020
Article
MicroRNA‑383‑5p inhibits the proliferation and promotes the apoptosis of gastric cancer cells by targeting cancerous inhibitor of PP2A
Xinxin Li, Jinpeng Yuan, Qiangjian Cao, Aosi Xie, Juntian Chen
Pages: 397-405 Published online on: 12 May 2020
Article
Downregulation of miR‑141 deactivates hepatic stellate cells by targeting the PTEN/AKT/mTOR pathway
Haijun Liang, Xinwei Wang, Changyun Si, Yuxiu Duan, Baoxin Chen, Haixia Liang, Daokun Yang
Pages: 406-414 Published online on: 15 April 2020
Article
Phorbol myristate acetate induces cellular senescence in rat microglia in vitro
Dan Cao, Xiao-Hong Li, Xiao-Guang Luo, Hong-Mei Yu, Li-Shu Wan, Ling Wei, Yan Ren
Pages: 415-426 Published online on: 23 April 2020
Article
Promotion of liver regeneration and anti‑fibrotic effects of the TGF‑β receptor kinase inhibitor galunisertib in CCl4‑treated mice
Atsutaka Masuda, Toru Nakamura, Mitsuhiko Abe, Hideki Iwamoto, Takahiko Sakaue, Toshimitsu Tanaka, Hiroyuki Suzuki, Hironori Koga, Takuji Torimura
Pages: 427-438 Published online on: 05 May 2020
Article
Propofol induces apoptosis by activating caspases and the MAPK pathways, and inhibiting the Akt pathway in TM3 mouse Leydig stem/progenitor cells
Fu‑Chi Kang, Yun‑Chia Chen, Shu‑Chun Wang, Edmund Cheung So, Bu‑Miin Huang
Pages: 439-448 Published online on: 21 April 2020
Article