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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2020 Volume 46 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Towards effective COVID‑19 vaccines: Updates, perspectives and challenges (Review)

Daniela Calina, Anca Oana Docea, Demetrios Petrakis, Alex M. Egorov, Aydar A. Ishmukhametov, Alexsandr G. Gabibov, Michael I. Shtilman, Ronald Kostoff, Félix Carvalho, Marco Vinceti, Demetrios A. Spandidos, Aristidis Tsatsakis
Pages: 3-16
Published online on: 06 May 2020

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Review Open Access

Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review)

Anatoly V. Skalny, Lothar Rink, Olga P. Ajsuvakova, Michael Aschner, Viktor A. Gritsenko, Svetlana I. Alekseenko, Andrey A. Svistunov, Demetrios Petrakis, Demetrios A. Spandidos, Jan Aaseth, Aristidis Tsatsakis, Alexey A. Tinkov
Pages: 17-26
Published online on: 14 April 2020

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Review Open Access

Large intestine embryogenesis: Molecular pathways and related disorders (Review)

Antonios Kostouros, Ioannis Koliarakis, Konstantinos Natsis, Demetrios A. Spandidos, Aristidis Tsatsakis, John Tsiaoussis
Pages: 27-57
Published online on: 21 April 2020

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Article Open Access

HIKESHI silencing can enhance mild hyperthermia sensitivity in human oral squamous cell carcinoma HSC‑3 cells

Yoshiaki Tabuchi, Keita Maekawa, Misako Torigoe, Yukihiro Furusawa, Tetsushi Hirano, Satsuki Minagawa, Tatsuya Yunoki, Atsushi Hayashi
Pages: 58-66
Published online on: 28 April 2020

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Article Open Access

Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generation

Ying‑Hui Kong, Su‑Ping Xu
Pages: 67-82
Published online on: 24 April 2020

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Article Open Access

Emerging roles of let‑7d in attenuating pulmonary arterial hypertension via suppression of pulmonary artery endothelial cell autophagy and endothelin synthesis through ATG16L1 downregulation

Minghui Ou, Xia Li, Shichao Cui, Shibo Zhao, Jie Tu
Pages: 83-96
Published online on: 07 April 2020

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Article Open Access

Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p

Yinghao Cao, Wenfei Lv, Wan Ding, Jun Li
Pages: 97-106
Published online on: 14 April 2020

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Article Open Access

CircSAMD4A regulates cell progression and epithelial‑mesenchymal transition by sponging miR‑342‑3p via the regulation of FZD7 expression in osteosarcoma

Chuhai Xie, Binwei Chen, Boyi Wu, Jianhong Guo, Yulong Shi, Yanming Cao
Pages: 107-118
Published online on: 22 April 2020

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Article Open Access

Long non‑coding RNA PRNCR1 exerts oncogenic effects in tongue squamous cell carcinoma in vitro and in vivo by sponging microRNA‑944 and thereby increasing HOXB5 expression Retraction in /10.3892/ijmm.2022.5183

Cong Lin, Yanan Zou, Ruijing Li, Daofeng Liu
Pages: 119-130
Published online on: 16 April 2020

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Article Open Access

MicroRNA‑17 contributes to the suppression of the inflammatory response in lipopolysaccharide‑induced acute lung injury in mice via targeting the toll‑like receptor 4/nuclear factor‑κB pathway

Shan Fu
Pages: 131-140
Published online on: 12 May 2020

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Article Open Access

TGF‑β1 induces CREB1‑mediated miR‑1290 upregulation to antagonize lung fibrosis via Napsin A

Shuhong Guan, Yudi Wu, Qiudi Zhang, Jun Zhou
Pages: 141-148
Published online on: 03 April 2020

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Article Open Access

NED416, a novel synthetic Sirt1 activator, promotes cutaneous wound healing via the MAPK/Rho pathway

Hussain Mustatab Wahedi, Jae Khyung Chae, Lalita Subedi, Min Cheol Kang, Hyunkyung Cho, Sanghee Kim, Sun Yeou Kim
Pages: 149-158
Published online on: 03 April 2020

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Article Open Access

LncRNA BCAR4 promotes liver cancer progression by upregulating ANAPC11 expression through sponging miR‑1261

Yu Zhang, Hongyan Zhou
Pages: 159-166
Published online on: 22 April 2020

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Article Open Access

Osteocyte TGFβ1‑Smad2/3 is positively associated with bone turnover parameters in subchondral bone of advanced osteoarthritis

Guangming Dai, Haozhuo Xiao, Junyi Liao, Nian Zhou, Chen Zhao, Wei Xu, Wenjuan Xu, Xi Liang, Wei Huang
Pages: 167-178
Published online on: 14 April 2020

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Article Open Access

Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts

Jianghong Gao, Xinmei Li, Liping Gao, Haiyan Chen, Bashayer H. Baras, Xiaojing Liu, Hao Liu, Ayesha Rana, Meili Gao, Jianping Ruan
Pages: 179-190
Published online on: 12 May 2020

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Article Open Access

The JAK2/STAT3 pathway inhibitor, AG490, suppresses the abnormal behavior of keloid fibroblasts in vitro

Ying Zhou, Yuexin Sun, Wenjun Hou, Liwen Ma, Yue Tao, Dan Li, Cui Xu, Jun Bao, Weixin Fan
Pages: 191-200
Published online on: 29 April 2020

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Article Open Access

XPD inhibits cell growth and invasion and enhances chemosensitivity in esophageal squamous cell carcinoma by regulating the PI3K/AKT signaling pathway

Jie Jian, Shuang Li, Li‑Zhen Liu, Li Zhen, Ling Yao, Li‑Hong Gan, Ya‑Qing Huang, Nian Fang
Pages: 201-210
Published online on: 04 May 2020

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Article Open Access

LRP6 is involved in the proliferation, migration and invasion of trophoblast cells via miR‑346

Lu Zhang, Huihui Li, Mingbao Li, Wenxia Zhang, Zhou Yang, Shuquan Zhang
Pages: 211-223
Published online on: 08 April 2020

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Article Open Access

Genome‑wide DNA methylation regulation analysis of long non‑coding RNAs in glioblastoma

Jianghuai Ji, Lei Zhao, Xiaoxiao Zhao, Qianpeng Li, Yi An, Li Li, Dongguo Li
Pages: 224-238
Published online on: 15 April 2020

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Article Open Access

Puerarin improves graft bone defect through microRNA‑155‑3p‑mediated p53/TNF‑α/STAT1 signaling pathway Retraction in /10.3892/ijmm.2024.5404

Yang Zhou, Hongyu Lian, Kexin Liu, Deli Wang, Xuelian Xiu, Zhang Sun
Pages: 239-251
Published online on: 06 May 2020

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Article Open Access

A risk score system based on DNA methylation levels and a nomogram survival model for lung squamous cell carcinoma

Ming Zhang, Libing Sun, Yi Ru, Shasha Zhang, Junjun Miao, Pengda Guo, Jinghuan Lv, Feng Guo, Biao Liu
Pages: 252-264
Published online on: 27 April 2020

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Article Open Access

Mechanism of Notch1‑saRNA‑1480 reversing androgen sensitivity in human metastatic castration‑resistant prostate cancer

Libin Ma, Kang Jiang, Peiwu Jiang, Han He, Kean Chen, Jia Shao, Gang Deng
Pages: 265-279
Published online on: 08 May 2020

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Article Open Access

Downregulation of c‑FLIP and upregulation of DR‑5 by cantharidin sensitizes TRAIL‑mediated apoptosis in prostate cancer cells via autophagy flux

Uddin Md Nazim, Honghua Yin, Sang‑Youel Park
Pages: 280-288
Published online on: 06 April 2020

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Article Open Access

Long non-coding RNA PART1 promotes intervertebral disc degeneration through regulating the miR‑93/MMP2 pathway in nucleus pulposus cells

Dongmei Gao, Long Hao, Zilong Zhao
Pages: 289-299
Published online on: 16 April 2020

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Article Open Access

EOFAZ inhibits endothelial‑to‑mesenchymal transition through downregulation of KLF4

Yanyan Zhang, Chen Li, Yongpan Huang, Shuang Zhao, Yini Xu, Yan Chen, Feng Jiang, Ling Tao, Xiangchun Shen
Pages: 300-310
Published online on: 09 April 2020

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Article Open Access

Cyclopamine functions as a suppressor of benign prostatic hyperplasia by inhibiting epithelial and stromal cell proliferation via suppression of the Hedgehog signaling pathway

Yi‑Feng Yuan, Wen‑Xiong Zhu, Tao Liu, Ju‑Qiao He, Qing Zhou, Xing Zhou, Xi Zhang, Jing Yang
Pages: 311-319
Published online on: 08 April 2020

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Article Open Access

Transient receptor potential canonical 1 channel mediates the mechanical stress‑induced epithelial‑mesenchymal transition of human bronchial epithelial (16HBE) cells

Jing Wang, Ye He, Gang Yang, Na Li, Minchao Li, Min Zhang
Pages: 320-330
Published online on: 07 April 2020

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Article Open Access

Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation

Rui Zhang, Liming Xu, Xiaoxia An, Xinbing Sui, Shuang Lin
Pages: 331-339
Published online on: 13 April 2020

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Article Open Access

Astragaloside IV protects retinal pigment epithelial cells from apoptosis by upregulating miR‑128 expression in diabetic rats

Tao Wang, Zhongwei Zhang, Caiping Song, Lei Sun, Xinli Sui, Qun Qu, Jing Liu
Pages: 340-350
Published online on: 23 April 2020

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Article Open Access

Spirulina protein promotes skin wound repair in a mouse model of full-thickness dermal excisional wound

Ping Liu, Jeong‑Wook Choi, Min‑Kyeong Lee, Youn Hee Choi, Taek‑Jeong Nam
Pages: 351-359
Published online on: 08 April 2020

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Article Open Access

MicroRNA‑1 regulates the development of osteoarthritis in a Col2a1‑Cre‑ERT2/GFPfl/fl‑RFP‑miR‑1 mouse model of osteoarthritis through the downregulation of Indian hedgehog expression

Xianda Che, Taoyu Chen, Lei Wei, Xiaodong Gu, Yangyang Gao, Shufen Liang, Penghua Li, Dongping Shi, Bin Liang, Chunfang Wang, Pengcui Li
Pages: 360-370
Published online on: 12 May 2020

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Article Open Access

Proteomic landscape of human coronary artery atherosclerosis

Yaqing Zhou, Jinxia Yuan, Yinwen Fan, Fenghui An, Jiaxin Chen, Yongjie Zhang, Jianliang Jin, Mufeng Gu, Zhiyuan Mao, Haijian Sun, Qiaowei Jia, Chenhui Zhao, Mingyue Ji, Jing Zhang, Guangxu Xu, Enzhi Jia
Pages: 371-383
Published online on: 12 May 2020

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Article Open Access

miR‑199a decreases Neuritin expression involved in the development of Alzheimer's disease in APP/PS1 mice

Dandan Song, Guoxiang Li, Yu Hong, Pan Zhang, Jingling Zhu, Lei Yang, Jin Huang
Pages: 384-396
Published online on: 12 May 2020

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Article

MicroRNA‑383‑5p inhibits the proliferation and promotes the apoptosis of gastric cancer cells by targeting cancerous inhibitor of PP2A

Xinxin Li, Jinpeng Yuan, Qiangjian Cao, Aosi Xie, Juntian Chen
Pages: 397-405
Published online on: 12 May 2020

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Article

Downregulation of miR‑141 deactivates hepatic stellate cells by targeting the PTEN/AKT/mTOR pathway

Haijun Liang, Xinwei Wang, Changyun Si, Yuxiu Duan, Baoxin Chen, Haixia Liang, Daokun Yang
Pages: 406-414
Published online on: 15 April 2020

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Article

Phorbol myristate acetate induces cellular senescence in rat microglia in vitro

Dan Cao, Xiao-Hong Li, Xiao-Guang Luo, Hong-Mei Yu, Li-Shu Wan, Ling Wei, Yan Ren
Pages: 415-426
Published online on: 23 April 2020

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Article

Promotion of liver regeneration and anti‑fibrotic effects of the TGF‑β receptor kinase inhibitor galunisertib in CCl4‑treated mice

Atsutaka Masuda, Toru Nakamura, Mitsuhiko Abe, Hideki  Iwamoto, Takahiko Sakaue, Toshimitsu Tanaka, Hiroyuki  Suzuki, Hironori Koga, Takuji Torimura
Pages: 427-438
Published online on: 05 May 2020

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Article

Propofol induces apoptosis by activating caspases and the MAPK pathways, and inhibiting the Akt pathway in TM3 mouse Leydig stem/progenitor cells

Fu‑Chi Kang, Yun‑Chia Chen, Shu‑Chun Wang, Edmund Cheung So, Bu‑Miin Huang
Pages: 439-448
Published online on: 21 April 2020

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Article Open Access

Cinnamaldehyde protects against oxidative stress and inhibits the TNF‑α‑induced inflammatory response in human umbilical vein endothelial cells

Nam‑Yi Kim, Nguyet‑Tran Trinh, Sang‑Gun Ahn, Soo‑A Kim
Pages: 449-457
Published online on: 16 April 2020

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Review Open Access

Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Review Open Access

Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Review Open Access

Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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Review Open Access

A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Review Open Access

Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Review Open Access

Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Review Open Access

Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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