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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2019 Volume 42 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

CAR T cell therapy: A new era for cancer treatment (Review)

Rimjhim Mohanty, Chitran Roy Chowdhury, Solomon Arega, Prakriti Sen, Pooja Ganguly, Niladri Ganguly
Pages: 2183-2195
Published online on: 24 September 2019

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Review

Cytotoxicity of Cichorium intybus L. metabolites (Review)

Khandaker Md Sharif Uddin Imam, Yingying Xie, Yusi Liu, Fengzhong Wang, Fengjiao Xin
Pages: 2196-2212
Published online on: 24 September 2019

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Review

Ibrutinib in CLL/SLL: From bench to bedside (Review)

Fuming Zi, Li Yu, Qingzhi Shi, Aiping Tang, Jing Cheng
Pages: 2213-2227
Published online on: 10 October 2019

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Review Open Access

Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review)

Theodore Krasanakis, Taxiarchis Konstantinos Nikolouzakis, Markos Sgantzos, Theodore Mariolis‑Sapsakos, John Souglakos, Demetrios A. Spandidos, Christina Tsitsimpikou, Aristidis Tsatsakis, John Tsiaoussis
Pages: 2228-2244
Published online on: 03 October 2019

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Article Open Access

Apurinic endonuclease 1 promotes the cisplatin resistance of lung cancer cells by inducing Parkin‑mediated mitophagy

Zheng Li, Yongqiang Wang, Linbo Wu, Yalu Dong, Jing Zhang, Fan Chen, Wei Xie, Jianguo Huang, Ning Lu
Pages: 2245-2254
Published online on: 01 October 2019

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Article Open Access

Genetic interactions between ANLN and KDR are prognostic for breast cancer survival

Xiaofeng Dai, Xiao Chen, Olivier Hakizimana, Yi Mei
Pages: 2255-2266
Published online on: 24 September 2019

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Article Open Access

Activation of the Toll‑like receptor 2 signaling pathway inhibits the proliferation of HCC cells in vitro

Yi Chen, Zuxiong Huang, Xuzheng Chen, Hanhui Ye
Pages: 2267-2278
Published online on: 27 September 2019

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Article Open Access

Prognostic significance of minichromosome maintenance mRNA expression in human lung adenocarcinoma

Shu Li, Zhou Jiang, Yirun Li, Yang Xu
Pages: 2279-2292
Published online on: 23 September 2019

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Article Open Access

p53 deficiency augments nucleolar instability after ionizing irradiation

Sangeeta Kakoti, Motohiro Yamauchi, Wenchao Gu, Reona Kato, Takaaki Yasuhara, Yoshihiko Hagiwara, Siddhartha Laskar, Takahiro Oike, Hiro Sato, Kathryn D. Held, Takashi Nakano, Atsushi Shibata
Pages: 2293-2302
Published online on: 27 September 2019

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Article Open Access

Mutations of RAS genes in endometrial polyps

Takashi Takeda, Kouji Banno, Yusuke Kobayashi, Masataka Adachi, Megumi Yanokura, Eiichiro Tominaga, Kenjiro Kosaki, Daisuke Aoki
Pages: 2303-2308
Published online on: 04 October 2019

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Article Open Access

HHLA2 is a novel prognostic predictor and potential therapeutic target in malignant glioma Corrigendum in /10.3892/or.2022.8473

Yangzhi Qi, Gang Deng, Pengfei Xu, Huikai Zhang, Fanen Yuan, Rongxin Geng, Hongxiang Jiang, Baohui Liu, Qianxue Chen
Pages: 2309-2322
Published online on: 01 October 2019

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Article Open Access

Expression of connective tissue growth factor as a prognostic indicator and its possible involvement in the aggressive properties of epithelial ovarian carcinoma

Akiko Shimbo, Hiroaki Kajiyama, Satoshi Tamauchi, Nobuhisa Yoshikawa, Yoshiki Ikeda, Kimihiro Nishino, Shiro Suzuki, Kaoru Niimi, Jun Sakata, Fumitaka Kikkawa
Pages: 2323-2332
Published online on: 03 October 2019

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Article Open Access

Gene mutation profile and risk stratification in AML1‑ETO‑positive acute myeloid leukemia based on next‑generation sequencing

Guopan Yu, Changxin Yin, Fuqun Wu, Ling Jiang, Zhongxin Zheng, Dan Xu, Jiaheng Zhou, Xuejie Jiang, Qifa Liu, Fanyi Meng
Pages: 2333-2344
Published online on: 15 October 2019

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Article Open Access

Antitumor activity of tetrandrine citrate in human glioma U87 cells in vitro and in vivo

Jingyu Sun, Yang Zhang, Yongzhan Zhen, Ju Cui, Gang Hu, Yajun Lin
Pages: 2345-2354
Published online on: 15 October 2019

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Article Open Access

Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype

Ya Xu, Xiangcai Yang, Shuting Mei, Yi Sun, Jiejing Li
Pages: 2355-2362
Published online on: 01 October 2019

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Article Open Access

Expression of DR5 and c‑FLIP proteins as novel prognostic biomarkers for non‑small cell lung cancer patients treated with surgical resection and chemotherapy

Hongmei Zheng, Yuting Zhang, Yuting Zhan, Sile Liu, Junmi Lu, Qiuyuan Wen, Songqing Fan
Pages: 2363-2370
Published online on: 04 October 2019

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Article Open Access

miRNA‑183‑5p.1 promotes the migration and invasion of gastric cancer AGS cells by targeting TPM1 Corrigendum in /10.3892/or.2020.7902

Jun Lin, Juan Shen, Hao Yue, Zhongwei Cao
Pages: 2371-2381
Published online on: 04 October 2019

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Article Open Access

Highly sensitive detection of sentinel lymph node metastasis of breast cancer by digital PCR for RASSF1A methylation

Mizuho Abe, Naofumi Kagara, Tomohiro Miyake, Tomonori Tanei, Yasuto Naoi, Masafumi Shimoda, Kenzo Shimazu, Seung Jin Kim , Shinzaburo Noguchi
Pages: 2382-2389
Published online on: 10 October 2019

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Article Open Access

miR‑489 promotes apoptosis and inhibits invasiveness of glioma cells by targeting PAK5/RAF1 signaling pathways Retraction in /10.3892/or.2023.8564

Wei Wang, Luyang Zhang, Wei Gao, Dongyong Zhang, Zilong Zhao, Yijun Bao
Pages: 2390-2401
Published online on: 22 October 2019

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Article Open Access

Construction of a competing endogenous RNA network using differentially expressed lncRNAs, miRNAs and mRNAs in non‑small cell lung cancer

Xi‑Wen Wang, Qi‑Qiang Guo, Yang Wei, Kai‑Ming Ren, Fu‑Shuang Zheng, Jun Tang, Hong‑Yan Zhang, Jun‑Gang Zhao
Pages: 2402-2415
Published online on: 17 October 2019

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Article Open Access

BH3 profiling discriminates the anti‑apoptotic status of 5‑fluorouracil‑resistant colon cancer cells

Kazuma Ishikawa, Yutaka Kawano, Yohei Arihara, Tomohiro Kubo, Kohichi Takada, Kazuyuki Murase, Koji Miyanishi, Masayoshi Kobune, Junji Kato
Pages: 2416-2425
Published online on: 15 October 2019

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Article Open Access

Targeting RAD51 enhances chemosensitivity of adult T‑cell leukemia‑lymphoma cells by reducing DNA double‑strand break repair

Meng Yang, Xiaoxue Tian, Zhuoyi Fan, Wenlei Yu, Zheng Li, Jie Zhou, Wenjun Zhang, Aibin Liang
Pages: 2426-2434
Published online on: 22 October 2019

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Article Open Access

Receptor‑interacting serine/threonine‑protein kinase 1 promotes the progress and lymph metastasis of gallbladder cancer

Guangwei Zhu, Qiang Du, Xiao Chen, Xiaoqian Wang, Nanhong Tang, Feifei She, Yanling Chen
Pages: 2435-2449
Published online on: 23 September 2019

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Article Open Access

Systematic profiling of a novel prognostic alternative splicing signature in hepatocellular carcinoma

Dong Zhang, Yi Duan, Zhe Wang, Jie Lin
Pages: 2450-2472
Published online on: 27 September 2019

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Article Open Access

Weighted gene coexpression analysis indicates that PLAGL2 and POFUT1 are related to the differential features of proximal and distal colorectal cancer

Yiming Lv, Binbin Xie, Bingjun Bai, Lina Shan, Wenqian Zheng, Xuefeng Huang, Hongbo Zhu
Pages: 2473-2485
Published online on: 14 October 2019

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Article Open Access

Ku80 gene knockdown by the CRISPR/Cas9 technique affects the biological functions of human thyroid carcinoma cells

Yali Fan, Jianying Li, Wei Wei, Hangrong Fang, Ying Duan, Namiao Li, Yingying Zhang, Jun Yu, Juanhong Wang
Pages: 2486-2498
Published online on: 01 October 2019

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Article Open Access

Effects of CCL5 on the biological behavior of breast cancer and the mechanisms of its interaction with tumor‑associated macrophages

Gaili An, Fang Wu, Shangke Huang, Lu Feng, Jun Bai, Shanzhi Gu, Xinhan Zhao
Pages: 2499-2511
Published online on: 01 October 2019

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Article Open Access

Core‑shell type thermo‑nanoparticles loaded with temozolomide combined with photothermal therapy in melanoma cells

Xiaoyang Hou, Yanyu Pang, Xinxin Li, Chunsheng Yang, Wenlou Liu, Guan Jiang, Yanqun Liu
Pages: 2512-2520
Published online on: 20 September 2019

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Article Open Access

Bradykinin promotes proliferation, migration, and invasion of cervical cancer cells through STAT3 signaling pathways

Wei Wang, Ying Zhou, Rui Wei, Guiying Jiang, Fei Li, Xi Chen, Xueqian Wang, Ding Ma, Ling Xi
Pages: 2521-2527
Published online on: 18 October 2019

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Article Open Access

Exosomes isolated from CAPS1‑overexpressing colorectal cancer cells promote cell migration

Bingrui Wu, Dalong Sun, Lijie Ma, Yiran Deng, Si Zhang, Ling Dong, She Chen
Pages: 2528-2536
Published online on: 09 October 2019

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Article Open Access

Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer

Zhiwei Cai, Yun Liang, Chun Xing, Hongwei Wang, Pengfei Hu, Jialin Li, Haiyan Huang, Wei Wang, Chongyi Jiang
Pages: 2537-2549
Published online on: 10 October 2019

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Article Open Access

miR‑425‑5p is associated with poor prognosis in patients with breast cancer and promotes cancer cell progression by targeting PTEN

Sheng Xiao, Hongjia Zhu, Jian Luo, Zhenru Wu, Mingjun Xie
Pages: 2550-2560
Published online on: 14 October 2019

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Article Open Access

β‑elemene inhibits the generation of peritoneum effusion in pancreatic cancer via suppression of the HIF1A‑VEGFA pathway based on network pharmacology

Junqiu Zhu, Bo Li, Yongsuo Ji, Linglin Zhu, Yanfei Zhu, Hong Zhao
Pages: 2561-2571
Published online on: 09 October 2019

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Article Open Access

Comprehensive analysis of the lncRNA‑associated competing endogenous RNA network in breast cancer

Jing‑Jing Wang, Yue‑Qing Huang, Wei Song, Yi‑Fan Li, Han Wang, Wen‑Jie Wang, Min Huang
Pages: 2572-2582
Published online on: 15 October 2019

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Article Open Access

Integrated analysis highlights multiple long non‑coding RNAs and their potential roles in the progression of human esophageal squamous cell carcinoma

Cheng‑Yun Li, Wen‑Wen Zhang, Ji‑Lian Xiang, Xing‑Hua Wang, Jun‑Ling Wang, Jin Li
Pages: 2583-2599
Published online on: 17 October 2019

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Article Open Access

Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β‑catenin pathway

Xiaocong Xiang, Rong Xiong, Chunlei Yu, Li Deng, Jun Bie, Dongqin Xiao, Zhu Chen, Yuchuan Zhou, Xiaolei Li, Kang Liu, Gang Feng
Pages: 2600-2610
Published online on: 16 October 2019

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Article Open Access

Ammonium tetrathiomolybdate enhances the antitumor effect of cisplatin via the suppression of ATPase copper transporting beta in head and neck squamous cell carcinoma

Shoji Ryumon, Tatsuo Okui, Yuki Kunisada, Koji Kishimoto, Tsuyoshi Shimo, Kazuaki Hasegawa, Soichiro Ibaragi, Kentaro Akiyama, Nguyen Thi Thu Ha, Nur Mohammad Monsur Hassan, Akira Sasaki
Pages: 2611-2621
Published online on: 10 October 2019

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Article Open Access

Identification of TPD52 and DNAJB1 as two novel bile biomarkers for cholangiocarcinoma by iTRAQ‑based quantitative proteomics analysis

Hongyue Ren, Mingxu Luo, Jinzhong Chen, Yanming Zhou, Xiumei Li, Yanyan Zhan, Dongyan Shen, Bo Chen
Pages: 2622-2634
Published online on: 23 October 2019

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Article Open Access

IFN‑β sensitizes TRAIL‑induced apoptosis by upregulation of death receptor 5 in malignant glioma cells

Sodai Yoshimura, Emiko Sano, Yuya Hanashima, Shun Yamamuro, Koichiro Sumi, Takuya Ueda, Tomohiro Nakayama, Hiroyuki Hara, Atsuo Yoshino, Yoichi Katayama
Pages: 2635-2643
Published online on: 22 October 2019

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Article Open Access

Involvement of CHOP in activin A‑induced myeloma NS‑1 cell apoptosis

Jingyan Ge, Hongyan Sun, Jing Li, Yidi Shan, Yang Zhao, Fangwei Liao, Yu Yang, Xueling Cui, Zhonghui Liu
Pages: 2644-2654
Published online on: 22 October 2019

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Article Open Access

Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim‑3 and galectin‑9, in cervical cancer

Li Zhang, Sijuan Tian, Meili Pei, Minyi Zhao, Li Wang, Yifan Jiang, Ting Yang, Juan Zhao, Lihua Song, Xiaofeng Yang
Pages: 2655-2669
Published online on: 24 October 2019

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Article

Knockdown of Nedd8‑conjugating enzyme UBE2M suppresses the proliferation and induces the apoptosis of intrahepatic cholangiocarcinoma cells

Bin Zhao, Caiyan Gao, Daixiu Shi, Jie Mao, Jun Zhao, Lingyun Guo, Jiwu Guo, Zuoyi Jiao
Pages: 2670-2679
Published online on: 20 September 2019

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Article

Development of recurrence risk score using 95‑gene classifier and its application to formalin‑fixed paraffin‑embedded tissues in ER‑positive, HER2‑negative and node‑negative breast cancer

Yasuto Naoi, Yuria Saito, Kazuki Kishi, Masafumi Shimoda, Naofumi Kagara, Tomohiro Miyake, Tomonori Tanei, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
Pages: 2680-2685
Published online on: 07 October 2019

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Article

A novel therapeutic anti‑CD55 monoclonal antibody inhibits the proliferation and metastasis of colorectal cancer cells

So Hee Dho, Eun Ha Cho, Ji Yeon Lee, So‑Young Lee, Sung Hee Jung, Lark Kyun Kim, Jae Cheong Lim
Pages: 2686-2693
Published online on: 26 September 2019

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Article

The prednisolone phosphate‑induced suppression of the angiogenic function of tumor‑associated macrophages enhances the antitumor effects of doxorubicin on B16.F10 murine melanoma cells in vitro

Emilia Licarete, Valentin Florian Rauca, Lavinia Luput, Laura Patras, Alina Sesarman, Manuela Banciu
Pages: 2694-2705
Published online on: 01 October 2019

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Article

SRPX and HMCN1 regulate cancer‑associated fibroblasts to promote the invasiveness of ovarian carcinoma

Chao Lien Liu, Hung Wei Pan, Pao Ling Torng, Ming Huei Fan, Tsui Lien Mao
Pages: 2706-2715
Published online on: 17 October 2019

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Article

Downregulation of MUTYH contributes to cisplatin‑resistance of esophageal squamous cell carcinoma cells by promoting Twist‑mediated EMT

Yanxia Guo, Yuxiu Jia, Shikang Wang, Ning Liu, Dongfang Gao, Lu Zhang, Zhaomin Lin, Shuling Wang, Feng Kong, Chuanliang Peng, Yongqing Liu
Pages: 2716-2727
Published online on: 01 October 2019

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Article

Upregulation of circular RNA circ‑FAM53B predicts adverse prognosis and accelerates the progression of ovarian cancer via the miR‑646/VAMP2 and miR‑647/MDM2 signaling pathways

Dan Sun, Jianing Liu, Lili Zhou
Pages: 2728-2737
Published online on: 10 October 2019

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Article

Microarray profile of circular RNAs identifies hsa_circRNA_102459 and hsa_circRNA_043621 as important regulators in oral squamous cell carcinoma

Wei Deng, Wei Peng, Tao Wang, Jingxin Chen, Xunding Qiu, Liangbin Fu, Shuangxi Zhu
Pages: 2738-2749
Published online on: 14 October 2019

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Article

High levels of Notch intracellular cleaved domain are associated with stemness and reduced bevacizumab efficacy in patients with advanced colon cancer

Francesca Negri, Cecilia Bozzetti, Giuseppe Pedrazzi, Cinzia Azzoni, Lorena Bottarelli, Anna Squadrilli, Costanza Lagrasta, Ione Tamagnini, Alessandra Bisagni, Moira Ragazzi, Rosa Porzio, Gianluca Tomasello, Daniele Mori, Francesco Leonardi, Letizia Gnetti, Pellegrino Crafa, Roberto Sala, Stefano Cascinu
Pages: 2750-2758
Published online on: 01 October 2019

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Article

Downregulation of miR‑143 modulates KRAS expression in colorectal carcinoma cells

Hong Liu, Jiansheng Liu, Junkai Huo, Kaihua Li, Kai Li, Haosu Guo, Yirong Yang
Pages: 2759-2767
Published online on: 07 October 2019

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Article

Targeting YAP suppresses ovarian cancer progression through regulation of the PI3K/Akt/mTOR pathway

Xiao Wei, Yijuan Jia, Hua Lou, Jingjing Ma, Quanfu Huang, Yunchong Meng, Chaoyang Sun, Zongyuan Yang, Xiaoting Li, Sen Xu, Xin Yang, Teng Ji, Qinglei Gao
Pages: 2768-2776
Published online on: 14 October 2019

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Article

RSK4 inhibits breast cancer cell proliferation and invasion in vitro, and is correlated with estrogen receptor upregulation in breast cancer

Hong Huo, Xinqing Ye, Honghe Yang, Qiuyun Li, Yi Jiang
Pages: 2777-2787
Published online on: 20 September 2019

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Article

Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants

Wenqing Li, Junhua Zhang, Lihui Zou, Jian Cui, Fei Su, Junhua Jin, Fei Xiao, Ming Liu, Gang Zhao
Pages: 2788-2796
Published online on: 24 September 2019

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Article

Suppressive effects of the sodium‑glucose cotransporter 2 inhibitor tofogliflozin on colorectal tumorigenesis in diabetic and obese mice

Junichi Kato, Yohei Shirakami, Masaya Ohnishi, Taku Mizutani, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Takuji Tanaka, Masahito Shimizu
Pages: 2797-2805
Published online on: 07 October 2019

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Article

Follistatin‑like protein 1 knockdown elicits human gastric cancer cell apoptosis via a STAT6‑dependent pathway

Xingang Peng, Peige Wang, Shikuan Li, Yingjun Jiang, Changliang Wu
Pages: 2806-2813
Published online on: 24 September 2019

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Article

Οlive tree blossom polyphenolic extracts exert antioxidant and antimutagenic activities in vitro and in various cell lines

Paraskevi Kouka, Fotios Tekos, Kalliopi Valta, Panagiotis Mavros, Aristidis S. Veskoukis, Apostolis Angelis, Alexios-Leandros Skaltsounis, Demetrios Kouretas
Pages: 2814-2825
Published online on: 23 October 2019

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Article

Establishment and characterization of a mouse tumor cell line with irreversible downregulation of MHC class I molecules

Karolina Lhotakova, Adrianna Grzelak, Ingrid Polakova, Julie Vackova, Michal Smahel
Pages: 2826-2835
Published online on: 04 October 2019

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Article

Potential role for second‑generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia harboring additional clonal chromosome abnormalities: A retrospective CML Cooperative Study Group analysis

Maho Ishikawa, Noriyoshi Iriyama, Michihide Tokuhira, Tomoiku Takaku, Eriko Sato, Kei‑Ji Sugimoto, Tomonori Nakazato, Hiroyuki Fujita, Yuta Kimura, Isao Fujioka, Norio Komatsu, Norio Asou, Masahiro Kizaki, Yoshihiro Hatta, Tatsuya Kawaguchi
Pages: 2836-2843
Published online on: 27 September 2019

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Article

DDR1 promotes breast tumor growth by suppressing antitumor immunity

Xing Zhong, Weiwei Zhang, Tianhao Sun
Pages: 2844-2854
Published online on: 27 September 2019

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Correction Open Access

[Corrigendum] A 19‑miRNA Support Vector Machine classifier and a 6‑miRNA risk score system designed for ovarian cancer patients

Jingwei Dong, Mingjun Xu
Pages: 2855-2855
Published online on: 23 October 2019

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Correction Open Access

[Corrigendum] Lycorine inhibits cell proliferation and migration by inhibiting ROCK1/cofilin‑induced actin dynamics in HepG2 hepatoblastoma cells

Wuyi Liu, Qian Zhang, Qin Tang, Changpeng  Hu, Jingbin  Huang, Yali Liu, Yanyi Lu, Qing  Wang, Guobing  Li, Rong Zhang
Pages: 2856-2856
Published online on: 10 October 2019

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Journal Cover
November-2026 Volume 56 Issue 5

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Targeting the DNHD1‑HDAC6 axis inactivates prostate cancer cell aggressiveness in vitro, suggesting potential therapeutic vulnerability

An Ni Lee, Chia Chang Wu, Su Wei Hu, Chih Heng Chen, Yi Te Chiang, Wei Tang Kao, Kai Yi Tzou, Chia Hung Liu, Shao Wei Dong, Yu Ting Wang, Yueh Lin Lee, Siou Bi Li, Che An Wu, Chiao Chun Liao, Ming Hsien Chan, Po Han Chiu, Chien Hsiu Li
Article Number: 198
Published online on: 30 September 2026

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Article Open Access

Loperamide enhances the radiosensitivity of cervical cancer cells via ferroptosis induction

Huarong Guo, Haixia Li, Shunkang Tian, Yunkai Zhang, Fuyun Wu, Jing Ke
Article Number: 197
Published online on: 30 September 2026

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Review Open Access

Mitochondrial mechanisms underlying spatial immune phenotypes in non‑small cell lung cancer: Implications for ICI response and cold‑to‑hot tumor conversion (Review)

Hongyi Lai, Ke Sun, Tong Mu, Xi Liu, Mingshan Liu
Article Number: 196
Published online on: 30 September 2026

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Article Open Access

PINK1 promotes the progression of lung squamous cell carcinoma through the FAK/AKT/RhoA/vinculin pathway

Xu Li, Yuhui Ma
Article Number: 195
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑195‑5p is a potential diagnostic and therapeutic target for breast cancer

Qifeng Luo, Chuankui Wei, Xiaoyu Li, Jia Li, Lei Chen, Yixiang Huang, Hongming Song, Dengfeng Li, Lin Fang
Article Number: 194
Published online on: 23 September 2026

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Article Open Access

SGPP1 as a tumor suppressor in esophageal squamous cell carcinoma: Potential molecular mechanisms involving UGT1A9/UGT2B28 and clinical prognostic significance

Linlin Su, Liubing Hou, Xuetao Han, Ge Zhang, Jiayuan Li, Yu Wang, Yuxin Han, Xiaoying Xue, Huandi Zhou
Article Number: 193
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo
Article Number: 192
Published online on: 21 September 2026

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Review Open Access

Overcoming melanoma drug resistance: Mechanisms and clinical progress of oncolytic viruses combined with immune checkpoint inhibitors (Review)

Yuan He, Wenxuan Lin, Haofang Chen, Yongqi Guan, Congcong Guan, Yanxiang Zhang, Dongsheng Pan
Article Number: 191
Published online on: 17 September 2026

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Article Open Access

Validation of next‑generation sequencing‑derived circulating mRNA variants as potential diagnostic tools in hepatocellular carcinoma and cholangiocarcinoma

Daniel Zezulinski, Maarouf A. Hoteit, David E. Kaplan, Tingting Zhan, Cataldo Doria, Timothy M. Block, Aejaz Sayeed
Article Number: 190
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer

Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Article Number: 189
Published online on: 16 September 2026

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Article Open Access

Pemetrexed increases BRCA1 protein stability and sensitizes TNBC cells to radiotherapy

Hee Jin, Kyung-Hwa Jeon, Chaerin Kang, Joohyun Lee, Yeonjin Lee, Youngjoo Kwon, Yun-Sil Lee
Article Number: 188
Published online on: 15 September 2026

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Article Open Access

FXYD5 promotes the growth of glioblastoma by targeting the PI3K/AKT/ACSL4 signaling axis

Bang Wang, Yong Qin, Hang Cheng, Yibin Zeng, Lianglei Jiang, Xuebin Hu
Article Number: 187
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] RIP kinase‑mediated ROS production triggers XAF1 expression through activation of TAp73 in casticin‑treated bladder cancer cells

Yoon Hee Chung, Daejin Kim
Article Number: 186
Published online on: 14 September 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo activities of an antitumor peptide HM‑3: A special dose‑efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Article Number: 185
Published online on: 10 September 2026

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Article Open Access

Effect of EZH2 regulation of the JAK2/STAT3 signaling pathway on proliferation and apoptosis in non‑small cell lung cancer cells

Shuang Wu, Wei Zhang
Article Number: 184
Published online on: 08 September 2026

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Correction Open Access

[Corrigendum] TGF‑β1 mediates epithelial to mesenchymal transition via the TGF‑β/Smad pathway in squamous cell carcinoma of the head and neck

Changyun Yu, Yong Liu, Donghai Huang, Yaozhang Dai, Gengming Cai, Jinjie Sun, Ting Xu, Yongquan Tian, Xin Zhang
Article Number: 183
Published online on: 31 August 2026

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Journal Cover
December-2026 Volume 56 Issue 6

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Journal Metrics

Impact Factor: 4.7

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in resistance mechanisms and counterstrategies for antibody‑drug conjugates in HER2‑low and HER2‑ultralow breast cancer (Review)

Xiaojie Yu, Meilin Ren, Longdi Yao
Article Number: 208
Published online on: 20 October 2026

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Article Open Access

CHCHD2 as a prognostic biomarker and therapeutic target in lung adenocarcinoma: Insights from pan‑cancer multi‑omics and functional studies

Zikai Xu, Jie Shen, Yizhou Lin, Haotian Shi, Cong Zhang, Zhengwei Zhang, Xiaoyu Zhou, Zheng Yang
Article Number: 207
Published online on: 15 October 2026

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Article Open Access

PBRM1 knockdown is associated with NRF2‑dependent ALDOA upregulation and metabolic reprogramming in HCCC‑9810 intrahepatic cholangiocarcinoma cells

Dong Zhang, Dezheng Liu, Shukuan Yang, Zijian Zhao, Xuekai Zhao, Yongshuo Liu, Fan Zhang, Lei Zhou
Article Number: 206
Published online on: 15 October 2026

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Article Open Access

SEC31A promotes gastric cancer progression by inducing the PI3K/AKT/mTOR pathway and enhancing the CCL5‑mediated M2 polarization and recruitment of tumor‑associated macrophages

Xixian Zhao, Liuye Huang
Article Number: 205
Published online on: 14 October 2026

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Review

Advances in neoadjuvant therapy for locally advanced head and neck squamous cell carcinoma (Review)

Hong You, Xinghu Qin, Shaozhi Fu
Article Number: 204
Published online on: 14 October 2026

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Review Open Access

miR‑324‑5p in oncology: Molecular mechanisms and clinical outlook (Review)

Kun Zhang, Zhen Xu, Yan Bin Luo, Chao Qi Liu, Yong Qin Zhou
Article Number: 203
Published online on: 13 October 2026

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Review Open Access

PRMT7 at the crossroads of cancer progression and therapeutic targeting (Review)

Yuchen He, Jiayi Lou, Yijing Huang, Wen Deng, Xuehong Cai
Article Number: 202
Published online on: 08 October 2026

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Retraction Open Access

[Retracted] miR‑29a inhibits human retinoblastoma progression by targeting STAT3

Shu Liu, Xiaomeng Zhang, Chunmei Hu, Yingxue Wang, Chunling Xu
Article Number: 201
Published online on: 08 October 2026

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Article Open Access

Expression of V‑domain Ig suppressor of T cell activation in ovarian cancer and its regulation of follicular regulatory T‑cell function via the AKT/MAPK pathway

Yan Ma, Yidan Xu, Chunxia Yu, Huatuo Wu, Li Li
Article Number: 200
Published online on: 07 October 2026

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Expression of Concern Open Access

[Expression of Concern] ZNF703 promotes tumor cell proliferation and invasion and predicts poor prognosis in patients with colorectal cancer

Feng Ma, Lihong Bi, Gongli Yang, Mengnan Zhang, Cuiping Liu, Yingying Zhao, Yadong Wang, Jide Wang, Yang Bai, Yali Zhang
Article Number: 199
Published online on: 30 September 2026

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