Journal Articles
Review
CAR T cell therapy: A new era for cancer treatment (Review)
Rimjhim Mohanty, Chitran Roy Chowdhury, Solomon Arega, Prakriti Sen, Pooja Ganguly, Niladri Ganguly
Pages: 2183-2195 Published online on: 24 September 2019
Review
Cytotoxicity of Cichorium intybus L. metabolites (Review)
Khandaker Md Sharif Uddin Imam, Yingying Xie, Yusi Liu, Fengzhong Wang, Fengjiao Xin
Pages: 2196-2212 Published online on: 24 September 2019
Review
Ibrutinib in CLL/SLL: From bench to bedside (Review)
Fuming Zi, Li Yu, Qingzhi Shi, Aiping Tang, Jing Cheng
Pages: 2213-2227 Published online on: 10 October 2019
Review
Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review)
Theodore Krasanakis, Taxiarchis Konstantinos Nikolouzakis, Markos Sgantzos, Theodore Mariolis‑Sapsakos, John Souglakos, Demetrios A. Spandidos, Christina Tsitsimpikou, Aristidis Tsatsakis, John Tsiaoussis
Pages: 2228-2244 Published online on: 03 October 2019
Article
Apurinic endonuclease 1 promotes the cisplatin resistance of lung cancer cells by inducing Parkin‑mediated mitophagy
Zheng Li, Yongqiang Wang, Linbo Wu, Yalu Dong, Jing Zhang, Fan Chen, Wei Xie, Jianguo Huang, Ning Lu
Pages: 2245-2254 Published online on: 01 October 2019
Article
Genetic interactions between ANLN and KDR are prognostic for breast cancer survival
Xiaofeng Dai, Xiao Chen, Olivier Hakizimana, Yi Mei
Pages: 2255-2266 Published online on: 24 September 2019
Article
Activation of the Toll‑like receptor 2 signaling pathway inhibits the proliferation of HCC cells in vitro
Yi Chen, Zuxiong Huang, Xuzheng Chen, Hanhui Ye
Pages: 2267-2278 Published online on: 27 September 2019
Article
Prognostic significance of minichromosome maintenance mRNA expression in human lung adenocarcinoma
Shu Li, Zhou Jiang, Yirun Li, Yang Xu
Pages: 2279-2292 Published online on: 23 September 2019
Article
p53 deficiency augments nucleolar instability after ionizing irradiation
Sangeeta Kakoti, Motohiro Yamauchi, Wenchao Gu, Reona Kato, Takaaki Yasuhara, Yoshihiko Hagiwara, Siddhartha Laskar, Takahiro Oike, Hiro Sato, Kathryn D. Held, Takashi Nakano, Atsushi Shibata
Pages: 2293-2302 Published online on: 27 September 2019
Article
Mutations of RAS genes in endometrial polyps
Takashi Takeda, Kouji Banno, Yusuke Kobayashi, Masataka Adachi, Megumi Yanokura, Eiichiro Tominaga, Kenjiro Kosaki, Daisuke Aoki
Pages: 2303-2308 Published online on: 04 October 2019
Article
HHLA2 is a novel prognostic predictor and potential therapeutic target in malignant glioma Corrigendum in /10.3892/or.2022.8473
Yangzhi Qi, Gang Deng, Pengfei Xu, Huikai Zhang, Fanen Yuan, Rongxin Geng, Hongxiang Jiang, Baohui Liu, Qianxue Chen
Pages: 2309-2322 Published online on: 01 October 2019
Article
Expression of connective tissue growth factor as a prognostic indicator and its possible involvement in the aggressive properties of epithelial ovarian carcinoma
Akiko Shimbo, Hiroaki Kajiyama, Satoshi Tamauchi, Nobuhisa Yoshikawa, Yoshiki Ikeda, Kimihiro Nishino, Shiro Suzuki, Kaoru Niimi, Jun Sakata, Fumitaka Kikkawa
Pages: 2323-2332 Published online on: 03 October 2019
Article
Gene mutation profile and risk stratification in AML1‑ETO‑positive acute myeloid leukemia based on next‑generation sequencing
Guopan Yu, Changxin Yin, Fuqun Wu, Ling Jiang, Zhongxin Zheng, Dan Xu, Jiaheng Zhou, Xuejie Jiang, Qifa Liu, Fanyi Meng
Pages: 2333-2344 Published online on: 15 October 2019
Article
Antitumor activity of tetrandrine citrate in human glioma U87 cells in vitro and in vivo
Jingyu Sun, Yang Zhang, Yongzhan Zhen, Ju Cui, Gang Hu, Yajun Lin
Pages: 2345-2354 Published online on: 15 October 2019
Article
Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype
Ya Xu, Xiangcai Yang, Shuting Mei, Yi Sun, Jiejing Li
Pages: 2355-2362 Published online on: 01 October 2019
Article
Expression of DR5 and c‑FLIP proteins as novel prognostic biomarkers for non‑small cell lung cancer patients treated with surgical resection and chemotherapy
Hongmei Zheng, Yuting Zhang, Yuting Zhan, Sile Liu, Junmi Lu, Qiuyuan Wen, Songqing Fan
Pages: 2363-2370 Published online on: 04 October 2019
Article
miRNA‑183‑5p.1 promotes the migration and invasion of gastric cancer AGS cells by targeting TPM1 Corrigendum in /10.3892/or.2020.7902
Jun Lin, Juan Shen, Hao Yue, Zhongwei Cao
Pages: 2371-2381 Published online on: 04 October 2019
Article
Highly sensitive detection of sentinel lymph node metastasis of breast cancer by digital PCR for RASSF1A methylation
Mizuho Abe, Naofumi Kagara, Tomohiro Miyake, Tomonori Tanei, Yasuto Naoi, Masafumi Shimoda, Kenzo Shimazu, Seung Jin Kim , Shinzaburo Noguchi
Pages: 2382-2389 Published online on: 10 October 2019
Article
miR‑489 promotes apoptosis and inhibits invasiveness of glioma cells by targeting PAK5/RAF1 signaling pathways Retraction in /10.3892/or.2023.8564
Wei Wang, Luyang Zhang, Wei Gao, Dongyong Zhang, Zilong Zhao, Yijun Bao
Pages: 2390-2401 Published online on: 22 October 2019
Article
Construction of a competing endogenous RNA network using differentially expressed lncRNAs, miRNAs and mRNAs in non‑small cell lung cancer
Xi‑Wen Wang, Qi‑Qiang Guo, Yang Wei, Kai‑Ming Ren, Fu‑Shuang Zheng, Jun Tang, Hong‑Yan Zhang, Jun‑Gang Zhao
Pages: 2402-2415 Published online on: 17 October 2019
Article
BH3 profiling discriminates the anti‑apoptotic status of 5‑fluorouracil‑resistant colon cancer cells
Kazuma Ishikawa, Yutaka Kawano, Yohei Arihara, Tomohiro Kubo, Kohichi Takada, Kazuyuki Murase, Koji Miyanishi, Masayoshi Kobune, Junji Kato
Pages: 2416-2425 Published online on: 15 October 2019
Article
Targeting RAD51 enhances chemosensitivity of adult T‑cell leukemia‑lymphoma cells by reducing DNA double‑strand break repair
Meng Yang, Xiaoxue Tian, Zhuoyi Fan, Wenlei Yu, Zheng Li, Jie Zhou, Wenjun Zhang, Aibin Liang
Pages: 2426-2434 Published online on: 22 October 2019
Article
Receptor‑interacting serine/threonine‑protein kinase 1 promotes the progress and lymph metastasis of gallbladder cancer
Guangwei Zhu, Qiang Du, Xiao Chen, Xiaoqian Wang, Nanhong Tang, Feifei She, Yanling Chen
Pages: 2435-2449 Published online on: 23 September 2019
Article
Systematic profiling of a novel prognostic alternative splicing signature in hepatocellular carcinoma
Dong Zhang, Yi Duan, Zhe Wang, Jie Lin
Pages: 2450-2472 Published online on: 27 September 2019
Article
Weighted gene coexpression analysis indicates that PLAGL2 and POFUT1 are related to the differential features of proximal and distal colorectal cancer
Yiming Lv, Binbin Xie, Bingjun Bai, Lina Shan, Wenqian Zheng, Xuefeng Huang, Hongbo Zhu
Pages: 2473-2485 Published online on: 14 October 2019
Article
Ku80 gene knockdown by the CRISPR/Cas9 technique affects the biological functions of human thyroid carcinoma cells
Yali Fan, Jianying Li, Wei Wei, Hangrong Fang, Ying Duan, Namiao Li, Yingying Zhang, Jun Yu, Juanhong Wang
Pages: 2486-2498 Published online on: 01 October 2019
Article
Effects of CCL5 on the biological behavior of breast cancer and the mechanisms of its interaction with tumor‑associated macrophages
Gaili An, Fang Wu, Shangke Huang, Lu Feng, Jun Bai, Shanzhi Gu, Xinhan Zhao
Pages: 2499-2511 Published online on: 01 October 2019
Article
Core‑shell type thermo‑nanoparticles loaded with temozolomide combined with photothermal therapy in melanoma cells
Xiaoyang Hou, Yanyu Pang, Xinxin Li, Chunsheng Yang, Wenlou Liu, Guan Jiang, Yanqun Liu
Pages: 2512-2520 Published online on: 20 September 2019
Article
Bradykinin promotes proliferation, migration, and invasion of cervical cancer cells through STAT3 signaling pathways
Wei Wang, Ying Zhou, Rui Wei, Guiying Jiang, Fei Li, Xi Chen, Xueqian Wang, Ding Ma, Ling Xi
Pages: 2521-2527 Published online on: 18 October 2019
Article
Exosomes isolated from CAPS1‑overexpressing colorectal cancer cells promote cell migration
Bingrui Wu, Dalong Sun, Lijie Ma, Yiran Deng, Si Zhang, Ling Dong, She Chen
Pages: 2528-2536 Published online on: 09 October 2019
Article
Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer
Zhiwei Cai, Yun Liang, Chun Xing, Hongwei Wang, Pengfei Hu, Jialin Li, Haiyan Huang, Wei Wang, Chongyi Jiang
Pages: 2537-2549 Published online on: 10 October 2019
Article
miR‑425‑5p is associated with poor prognosis in patients with breast cancer and promotes cancer cell progression by targeting PTEN
Sheng Xiao, Hongjia Zhu, Jian Luo, Zhenru Wu, Mingjun Xie
Pages: 2550-2560 Published online on: 14 October 2019
Article
β‑elemene inhibits the generation of peritoneum effusion in pancreatic cancer via suppression of the HIF1A‑VEGFA pathway based on network pharmacology
Junqiu Zhu, Bo Li, Yongsuo Ji, Linglin Zhu, Yanfei Zhu, Hong Zhao
Pages: 2561-2571 Published online on: 09 October 2019
Article
Comprehensive analysis of the lncRNA‑associated competing endogenous RNA network in breast cancer
Jing‑Jing Wang, Yue‑Qing Huang, Wei Song, Yi‑Fan Li, Han Wang, Wen‑Jie Wang, Min Huang
Pages: 2572-2582 Published online on: 15 October 2019
Article
Integrated analysis highlights multiple long non‑coding RNAs and their potential roles in the progression of human esophageal squamous cell carcinoma
Cheng‑Yun Li, Wen‑Wen Zhang, Ji‑Lian Xiang, Xing‑Hua Wang, Jun‑Ling Wang, Jin Li
Pages: 2583-2599 Published online on: 17 October 2019
Article
Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β‑catenin pathway
Xiaocong Xiang, Rong Xiong, Chunlei Yu, Li Deng, Jun Bie, Dongqin Xiao, Zhu Chen, Yuchuan Zhou, Xiaolei Li, Kang Liu, Gang Feng
Pages: 2600-2610 Published online on: 16 October 2019
Article
Ammonium tetrathiomolybdate enhances the antitumor effect of cisplatin via the suppression of ATPase copper transporting beta in head and neck squamous cell carcinoma
Shoji Ryumon, Tatsuo Okui, Yuki Kunisada, Koji Kishimoto, Tsuyoshi Shimo, Kazuaki Hasegawa, Soichiro Ibaragi, Kentaro Akiyama, Nguyen Thi Thu Ha, Nur Mohammad Monsur Hassan, Akira Sasaki
Pages: 2611-2621 Published online on: 10 October 2019
Article
Identification of TPD52 and DNAJB1 as two novel bile biomarkers for cholangiocarcinoma by iTRAQ‑based quantitative proteomics analysis
Hongyue Ren, Mingxu Luo, Jinzhong Chen, Yanming Zhou, Xiumei Li, Yanyan Zhan, Dongyan Shen, Bo Chen
Pages: 2622-2634 Published online on: 23 October 2019
Article
IFN‑β sensitizes TRAIL‑induced apoptosis by upregulation of death receptor 5 in malignant glioma cells
Sodai Yoshimura, Emiko Sano, Yuya Hanashima, Shun Yamamuro, Koichiro Sumi, Takuya Ueda, Tomohiro Nakayama, Hiroyuki Hara, Atsuo Yoshino, Yoichi Katayama
Pages: 2635-2643 Published online on: 22 October 2019
Article
Involvement of CHOP in activin A‑induced myeloma NS‑1 cell apoptosis
Jingyan Ge, Hongyan Sun, Jing Li, Yidi Shan, Yang Zhao, Fangwei Liao, Yu Yang, Xueling Cui, Zhonghui Liu
Pages: 2644-2654 Published online on: 22 October 2019
Article
Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim‑3 and galectin‑9, in cervical cancer
Li Zhang, Sijuan Tian, Meili Pei, Minyi Zhao, Li Wang, Yifan Jiang, Ting Yang, Juan Zhao, Lihua Song, Xiaofeng Yang
Pages: 2655-2669 Published online on: 24 October 2019
Article
Knockdown of Nedd8‑conjugating enzyme UBE2M suppresses the proliferation and induces the apoptosis of intrahepatic cholangiocarcinoma cells
Bin Zhao, Caiyan Gao, Daixiu Shi, Jie Mao, Jun Zhao, Lingyun Guo, Jiwu Guo, Zuoyi Jiao
Pages: 2670-2679 Published online on: 20 September 2019
Article
Development of recurrence risk score using 95‑gene classifier and its application to formalin‑fixed paraffin‑embedded tissues in ER‑positive, HER2‑negative and node‑negative breast cancer
Yasuto Naoi, Yuria Saito, Kazuki Kishi, Masafumi Shimoda, Naofumi Kagara, Tomohiro Miyake, Tomonori Tanei, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
Pages: 2680-2685 Published online on: 07 October 2019
Article
A novel therapeutic anti‑CD55 monoclonal antibody inhibits the proliferation and metastasis of colorectal cancer cells
So Hee Dho, Eun Ha Cho, Ji Yeon Lee, So‑Young Lee, Sung Hee Jung, Lark Kyun Kim, Jae Cheong Lim
Pages: 2686-2693 Published online on: 26 September 2019
Article
The prednisolone phosphate‑induced suppression of the angiogenic function of tumor‑associated macrophages enhances the antitumor effects of doxorubicin on B16.F10 murine melanoma cells in vitro
Emilia Licarete, Valentin Florian Rauca, Lavinia Luput, Laura Patras, Alina Sesarman, Manuela Banciu
Pages: 2694-2705 Published online on: 01 October 2019
Article
SRPX and HMCN1 regulate cancer‑associated fibroblasts to promote the invasiveness of ovarian carcinoma
Chao Lien Liu, Hung Wei Pan, Pao Ling Torng, Ming Huei Fan, Tsui Lien Mao
Pages: 2706-2715 Published online on: 17 October 2019
Article
Downregulation of MUTYH contributes to cisplatin‑resistance of esophageal squamous cell carcinoma cells by promoting Twist‑mediated EMT
Yanxia Guo, Yuxiu Jia, Shikang Wang, Ning Liu, Dongfang Gao, Lu Zhang, Zhaomin Lin, Shuling Wang, Feng Kong, Chuanliang Peng, Yongqing Liu
Pages: 2716-2727 Published online on: 01 October 2019
Article
Upregulation of circular RNA circ‑FAM53B predicts adverse prognosis and accelerates the progression of ovarian cancer via the miR‑646/VAMP2 and miR‑647/MDM2 signaling pathways
Dan Sun, Jianing Liu, Lili Zhou
Pages: 2728-2737 Published online on: 10 October 2019
Article
Microarray profile of circular RNAs identifies hsa_circRNA_102459 and hsa_circRNA_043621 as important regulators in oral squamous cell carcinoma
Wei Deng, Wei Peng, Tao Wang, Jingxin Chen, Xunding Qiu, Liangbin Fu, Shuangxi Zhu
Pages: 2738-2749 Published online on: 14 October 2019
Article
High levels of Notch intracellular cleaved domain are associated with stemness and reduced bevacizumab efficacy in patients with advanced colon cancer
Francesca Negri, Cecilia Bozzetti, Giuseppe Pedrazzi, Cinzia Azzoni, Lorena Bottarelli, Anna Squadrilli, Costanza Lagrasta, Ione Tamagnini, Alessandra Bisagni, Moira Ragazzi, Rosa Porzio, Gianluca Tomasello, Daniele Mori, Francesco Leonardi, Letizia Gnetti, Pellegrino Crafa, Roberto Sala, Stefano Cascinu
Pages: 2750-2758 Published online on: 01 October 2019
Article
Downregulation of miR‑143 modulates KRAS expression in colorectal carcinoma cells
Hong Liu, Jiansheng Liu, Junkai Huo, Kaihua Li, Kai Li, Haosu Guo, Yirong Yang
Pages: 2759-2767 Published online on: 07 October 2019
Article
Targeting YAP suppresses ovarian cancer progression through regulation of the PI3K/Akt/mTOR pathway
Xiao Wei, Yijuan Jia, Hua Lou, Jingjing Ma, Quanfu Huang, Yunchong Meng, Chaoyang Sun, Zongyuan Yang, Xiaoting Li, Sen Xu, Xin Yang, Teng Ji, Qinglei Gao
Pages: 2768-2776 Published online on: 14 October 2019
Article
RSK4 inhibits breast cancer cell proliferation and invasion in vitro, and is correlated with estrogen receptor upregulation in breast cancer
Hong Huo, Xinqing Ye, Honghe Yang, Qiuyun Li, Yi Jiang
Pages: 2777-2787 Published online on: 20 September 2019
Article
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants
Wenqing Li, Junhua Zhang, Lihui Zou, Jian Cui, Fei Su, Junhua Jin, Fei Xiao, Ming Liu, Gang Zhao
Pages: 2788-2796 Published online on: 24 September 2019
Article
Suppressive effects of the sodium‑glucose cotransporter 2 inhibitor tofogliflozin on colorectal tumorigenesis in diabetic and obese mice
Junichi Kato, Yohei Shirakami, Masaya Ohnishi, Taku Mizutani, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Takuji Tanaka, Masahito Shimizu
Pages: 2797-2805 Published online on: 07 October 2019
Article
Follistatin‑like protein 1 knockdown elicits human gastric cancer cell apoptosis via a STAT6‑dependent pathway
Xingang Peng, Peige Wang, Shikuan Li, Yingjun Jiang, Changliang Wu
Pages: 2806-2813 Published online on: 24 September 2019
Article
Οlive tree blossom polyphenolic extracts exert antioxidant and antimutagenic activities in vitro and in various cell lines
Paraskevi Kouka, Fotios Tekos, Kalliopi Valta, Panagiotis Mavros, Aristidis S. Veskoukis, Apostolis Angelis, Alexios-Leandros Skaltsounis, Demetrios Kouretas
Pages: 2814-2825 Published online on: 23 October 2019
Article
Establishment and characterization of a mouse tumor cell line with irreversible downregulation of MHC class I molecules
Karolina Lhotakova, Adrianna Grzelak, Ingrid Polakova, Julie Vackova, Michal Smahel
Pages: 2826-2835 Published online on: 04 October 2019
Article
Potential role for second‑generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia harboring additional clonal chromosome abnormalities: A retrospective CML Cooperative Study Group analysis
Maho Ishikawa, Noriyoshi Iriyama, Michihide Tokuhira, Tomoiku Takaku, Eriko Sato, Kei‑Ji Sugimoto, Tomonori Nakazato, Hiroyuki Fujita, Yuta Kimura, Isao Fujioka, Norio Komatsu, Norio Asou, Masahiro Kizaki, Yoshihiro Hatta, Tatsuya Kawaguchi
Pages: 2836-2843 Published online on: 27 September 2019
Article
DDR1 promotes breast tumor growth by suppressing antitumor immunity
Xing Zhong, Weiwei Zhang, Tianhao Sun
Pages: 2844-2854 Published online on: 27 September 2019
Correction
[Corrigendum] A 19‑miRNA Support Vector Machine classifier and a 6‑miRNA risk score system designed for ovarian cancer patients
Jingwei Dong, Mingjun Xu
Pages: 2855-2855 Published online on: 23 October 2019
Correction
