Journal Articles
Review
HIV‑1 integrase inhibitors targeting various DDE transposases: Retroviral integration versus RAG‑mediated recombination (Review)
Mihaela Georgiana Mușat, George Mihai Nițulescu, Marius Surleac, Aristidis Tsatsakis, Demetrios A. Spandidos, Denisa Margină
Pages: 4749-4762 Published online on: 30 October 2019
Review
Aryl hydrocarbon receptor pathway: Role, regulation and intervention in atherosclerosis therapy (Review)
Kaixi Zhu, Qingqi Meng, Zhi Zhang, Tao Yi, Yuan He, Jing Zheng, Wei Lei
Pages: 4763-4773 Published online on: 16 October 2019
Review
Role of endoplasmic reticulum stress in depression (Review)
Jiaxin Mao, Yanran Hu, Liemin Ruan, Yunxin Ji, Zhongze Lou
Pages: 4774-4780 Published online on: 31 October 2019
Article
miR‑455 targets FABP4 to protect human endometrial stromal cells from cytotoxicity induced by hydrogen peroxide
Wenbo Tang, Oujing Chen, Fengxiang Yao, Lining Cui
Pages: 4781-4790 Published online on: 04 October 2019
Article
CXCR4 and CXCR3 are two distinct prognostic biomarkers in breast cancer: Database mining for CXCR family members
Kaibo Guo, Guan Feng, Qingying Yan, Leitao Sun, Kai Zhang, Fengfei Shen, Minhe Shen, Shanming Ruan
Pages: 4791-4802 Published online on: 30 October 2019
Article
MicroRNA‑128‑b regulates epidermal growth factor receptor expression in non‑small cell lung cancer
Ling Li, Dongqing Wang
Pages: 4803-4810 Published online on: 08 October 2019
Article
Effects of D‑Ala2, D‑Leu5‑Enkephalin pre‑ and post‑conditioning in a rabbit model of spinal cord ischemia and reperfusion injury
Danyun Fu, Haitong Liu, Hua Liu, Junyan Yao
Pages: 4811-4820 Published online on: 07 October 2019
Article
Curcumin attenuates hypoxia/reoxygenation‑induced myocardial injury
Wenjuan Wei, Jun Peng, Jian Li
Pages: 4821-4830 Published online on: 15 October 2019
Article
CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells
Min Zhang, Mei Gao, Jinyu Chen, Lihua Song, Wei Wei
Pages: 4831-4842 Published online on: 23 October 2019
Article
miR‑760 regulates skeletal muscle proliferation in rheumatoid arthritis by targeting Myo18b
Xujun Tang, Jiuxia Wang, Shuhong Zhou, Jing Zhou, Guyou Jia, Han Wang, Chunlei Xin, Guoning Fu, Jiahong Zhang
Pages: 4843-4854 Published online on: 29 October 2019
Article
Chloroquine promotes gefitinib‑induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma
Chengshan Ou, Hongxia Liu, Zhenhua Ding, Liang Zhou
Pages: 4855-4866 Published online on: 09 October 2019
Article
Placental growth factor gene silencing mitigates the epithelial‑to‑mesenchymal transition via the p38 MAPK pathway in rats with hyperoxia‑induced lung injury
Shuang Zhao, Gang Luo, Hongmin Wu, Liang Zhang
Pages: 4867-4874 Published online on: 30 October 2019
Article
miR‑222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl‑2
Wei Wang, Jian Wang, Jiayi Zhang, Wei Taq, Zhenxing Zhang
Pages: 4875-4882 Published online on: 09 October 2019
Article
The JAK inhibitor tofacitinib ameliorates immune‑mediated liver injury in mice
Han Wang, Xinxia Feng, Ping Han, Yu Lei, Yujia Xia, Dean Tian, Wei Yan
Pages: 4883-4892 Published online on: 16 October 2019
Article
Theaflavin attenuates cerebral ischemia/reperfusion injury by abolishing miRNA‑128‑3p‑mediated Nrf2 inhibition and reducing oxidative stress
Ronggang Li, Xin Li, Haibing Wu, Zhikun Yang, Li Fei, Jianhong Zhu
Pages: 4893-4904 Published online on: 17 October 2019
Article
Whole‑exome sequencing in Russian children with non‑type 1 diabetes mellitus reveals a wide spectrum of genetic variants in MODY‑related and unrelated genes
Oleg S. Glotov, Elena A. Serebryakova, Mariia E. Turkunova, Olga A. Efimova, Andrey S. Glotov, Yury A. Barbitoff, Yulia A. Nasykhova, Alexander V. Predeus, Dmitrii E. Polev, Mikhail A. Fedyakov, Irina V. Polyakova, Tatyana E. Ivashchenko, Natalia Y. Shved, Elena S. Shabanova, Alena V. Tiselko, Olga V. Romanova, Andrey M. Sarana, Anna A. Pendina, Sergey G. Scherbak, Ekaterina V. Musina, Anastasiia V. Petrovskaia‑Kaminskaia, Liubov R. Lonishin, Liliya V. Ditkovskaya, Liudmila А. Zhelenina, Ludmila V. Tyrtova, Olga S. Berseneva, Rostislav K. Skitchenko, Evgenii N. Suspitsin, Elena B. Bashnina, Vladislav S. Baranov
Pages: 4905-4914 Published online on: 16 October 2019
Article
Clinical and molecular characterization of four patients with NTCP deficiency from two unrelated families harboring the novel SLC10A1 variant c.595A>C (p.Ser199Arg)
Hua Li, Mei Deng, Li Guo, Jian‑Wu Qiu, Gui‑Zhi Lin, Xiao‑Ling Long, Xiao‑Min Xiao, Yuan‑Zong Song
Pages: 4915-4924 Published online on: 23 October 2019
Article
Der p2‑A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis
Wenhui Hu, Li Ma, Gui Yang, Xianhai Zeng, Jiangqi Liu, Baohui Cheng, Tianyong Hu, Hailiang Zhao, Zhiqiang Liu
Pages: 4925-4932 Published online on: 21 October 2019
Article
Exendin‑4 promotes osteogenic differentiation of adipose‑derived stem cells and facilitates bone repair
Banglian Deng, Wenzhong Zhu, Yansheng Duan, Yuqian Hu, Xuefeng Chen, Shuang Song, Zian Yi, Yingliang Song
Pages: 4933-4942 Published online on: 23 October 2019
Article
Exopolysaccharide from Paecilomyces lilacinus modulates macrophage activities through the TLR4/NF‑κB/MAPK pathway
Chao He, Hai‑Yan Lin, Cai‑Chun Wang, Ming Zhang, Ying‑Ying Lin, Feng‑Ying Huang, Ying‑Zi Lin, Guang‑Hong Tan
Pages: 4943-4952 Published online on: 15 October 2019
Article
miR‑21‑5p ameliorates hyperoxic acute lung injury and decreases apoptosis of AEC II cells via PTEN/AKT signaling in rats
Song Qin, Hongliang Wang, Guoyue Liu, Hong Mei, Miao Chen
Pages: 4953-4962 Published online on: 30 October 2019
Article
Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF‑κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet
Qian Yu, Zhengyun Xia, Emily Chiu Liong, George Lim Tipoe
Pages: 4963-4972 Published online on: 31 October 2019
Article
MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3
Zhi‑Ying Li, Zi‑Zhou Zhang, Hui Bi, Qiu‑Di Zhang, Su‑Juan Zhang, Lin Zhou, Xiao‑Qin Zhu, Jun Zhou
Pages: 4973-4983 Published online on: 11 October 2019
Article
Formononetin attenuates monocrotaline‑induced pulmonary arterial hypertension via inhibiting pulmonary vascular remodeling in rats
Changhong Cai, Yijia Xiang, Yonghui Wu, Ning Zhu, Huan Zhao, Jian Xu, Wensheng Lin, Chunlai Zeng
Pages: 4984-4992 Published online on: 30 October 2019
Article
IL‑1β increases the expression of inflammatory factors in synovial fluid‑derived fibroblast‑like synoviocytes via activation of the NF‑κB‑mediated ERK‑STAT1 signaling pathway
Jie Yang, Junhu Wang, Xiaojun Liang, Hongmou Zhao, Jun Lu, Qiang Ma, Bingfei Jing, Feng Tian
Pages: 4993-5001 Published online on: 21 October 2019
Article
Upregulation of miR‑132‑3p in cholangiocarcinoma tissues: A study based on RT‑qPCR, The Cancer Genome Atlas miRNA sequencing, Gene Expression Omnibus microarray data and bioinformatics analyses
Hua‑Yu Wu, Shuang Xia, An‑Gui Liu, Min‑Da Wei, Zhong‑Biao Chen, Yu‑Xin Li, Yu He, Min‑Jun Liao, Qi‑Ping Hu, Shang‑Ling Pan
Pages: 5002-5020 Published online on: 07 October 2019
Article
SSTR5‑AS1 functions as a ceRNA to regulate CA2 by sponging miR‑15b‑5p for the development and prognosis of HBV‑related hepatocellular carcinoma
Jing Xu, Jing Zhang, Fenglian Shan, Jie Wen, Yue Wang
Pages: 5021-5031 Published online on: 11 October 2019
Article
Curcumin relieves paraquat‑induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3‑mediated inflammatory pathway
Yi Ren, Zhizhou Yang, Zhaorui Sun, Wei Zhang, Xin Chen, Shinan Nie
Pages: 5032-5040 Published online on: 23 August 2019
Article
Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a
Rui Li, Lianxin Wang
Pages: 5041-5049 Published online on: 15 October 2019
Article
Effects of β‑hydroxybutyric acid and ghrelin on the motility and inflammation of gastric antral smooth muscle cells involving the regulation of growth hormone secretagogue receptor
Xiaolin Hu, Li You, Changhua Hu, Juan Wu, Min Ai, Xiaoyan He, Wenjie Huang, Zonghui Wu
Pages: 5050-5058 Published online on: 11 October 2019
Article
Novel compound heterozygous PKHD1 mutations cause autosomal recessive polycystic kidney disease in a Han Chinese family
Jin Wang, Dandan Qi, Jialiang Yang, Dingding Zhang, Qingwei Wang, Xueming Ju, Xiang Zhong
Pages: 5059-5063 Published online on: 11 October 2019
Article
Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line
Jing Han, Yonghong Tang, Meizuo Zhong, Wenlin Wu
Pages: 5064-5074 Published online on: 17 October 2019
Article
Identification of dysregulated serum miR-508-3p and miR-885-5p as potential diagnostic biomarkers of clear cell renal carcinoma
Siming Liu, Xiaojun Deng, Jiong Zhang
Pages: 5075-5083 Published online on: 22 October 2019
Article
High glucose inhibits osteogenic differentiation and proliferation of MC3T3‑E1 cells by regulating P2X7
Jinsan Yang, Cao Ma, Maoshu Zhang
Pages: 5084-5090 Published online on: 31 October 2019
Article
C‑type natriuretic peptide prevents angiotensin II‑induced atrial connexin 40 and 43 dysregulation by activating AMP‑activated kinase signaling
Da‑Zhi Ding, Ya‑Nan Jia, Bo Zhang, Cheng‑Ming Guan, Shuai Zhou, Xiang Li, Xun Cui
Pages: 5091-5099 Published online on: 15 October 2019
Article
Cannabinoid receptor 2‑selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord
Yanting Mao, Yulin Huang, Ying Zhang, Chenchen Wang, Hao Wu, Xinyu Tian, Yue Liu, Bailing Hou, Ying Liang, Hui Rong, Xiaoping Gu, Zhengliang Ma
Pages: 5100-5110 Published online on: 25 October 2019
Article
Identification of whirlin domains interacting with espin: A study of the mechanism of Usher syndrome type II
Le Wang, Bo Wei, Xueqi Fu, Yuchen Wang, Yuan Sui, Junfeng Ma, Xianhui Gong, Jilong Hao, Shu Xing
Pages: 5111-5117 Published online on: 07 October 2019
Case Report
Idiopathic renal hypouricemia: A case report and literature review
Cuiyu Wang, Jin Wang, Song Liu, Xinhua Liang, Yifan Song, Ling Feng, Lanxin Zhong, Xiaohua Guo
Pages: 5118-5124 Published online on: 04 October 2019
Article
Effects of microRNA‑217 on high glucose‑induced inflammation and apoptosis of human retinal pigment epithelial cells (ARPE‑19) and its underlying mechanism
Hongxia Xiao, Zhen Liu
Pages: 5125-5133 Published online on: 30 October 2019
Article
Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury
Junjie Wang, Dongdong Fu, Soulixay Senouthai, Yanwu You
Pages: 5134-5144 Published online on: 09 October 2019
Article
Early‑onset epilepsy and microcephaly‑capillary malformation syndrome caused by a novel STAMBP mutation in a Chinese boy
Fangrui Wu, Ying Dai, Juan Wang, Min Cheng, Yanqin Wang, Xiujuan Li, Ping Yuan, Shuang Liao, Li Jiang, Jin Chen, Lisi Yan, Min Zhong
Pages: 5145-5151 Published online on: 17 October 2019
Article
Effect of electrical stimulation combined with diet therapy on insulin resistance via mTOR signaling
Siqin Huang, Nianzhen Tang, Hongdi Zhao, Cheng‑Lin Tang
Pages: 5152-5162 Published online on: 30 October 2019
Article
Nicotinamide phosphoribosyltransferase‑related signaling pathway in early Alzheimer's disease mouse models
Sanli Xing, Yiran Hu, Xujiao Huang, Dingzhu Shen, Chuan Chen
Pages: 5163-5171 Published online on: 30 October 2019
Article
miR‑593 inhibits proliferation and invasion and promotes apoptosis in non‑small cell lung cancer cells by targeting SLUG‑associated signaling pathways Corrigendum in /10.3892/mmr.2021.12555
Fang Wei, Mofei Wang, Zhen Li, Yong Wang, Yong Zhou
Pages: 5172-5182 Published online on: 29 October 2019
Article
Dexmedetomidine improves cardiac function and protects against maladaptive remodeling following myocardial infarction
Hui Han, Daopeng Dai, Jinquan Hu, Jinzhou Zhu, Lin Lu, Guorong Tao, Ruiyan Zhang
Pages: 5183-5189 Published online on: 29 October 2019
Article
Promotion of microglial phagocytosis by tuftsin stimulates remyelination in experimental autoimmune encephalomyelitis Corrigendum in /10.3892/mmr.2020.11042
Zheng Bao, Jinqi Hao, Yuhong Li, Fumin Feng
Pages: 5190-5196 Published online on: 31 October 2019
Article
Kaempferol promotes bone formation in part via the mTOR signaling pathway
Jing Zhao, Jue Wu, Binwu Xu, Zhen Yuan, Yu Leng, Jun Min, Xiaoyong Lan, Jun Luo
Pages: 5197-5207 Published online on: 16 October 2019
Article
miR‑486 acts as an oncogene and potential prognostic biomarker in renal cell carcinoma
Chengwen Sun, Caihong Sun, Yibin Zhou, Ganglong Yang, Guang Li, Congming Xiang, Xiqi Ding, Jian Sun
Pages: 5208-5215 Published online on: 25 October 2019
Article
Long noncoding RNA MIAT: A potential role in the diagnosis and mediation of acute myocardial infarction
Mayra Azat, Xiaokelaiti Huojiahemaiti, Ranran Gao, Peng Peng
Pages: 5216-5222 Published online on: 23 October 2019
Article
Oxyntomodulin attenuates TNF‑α induced neuropathic pain by inhibiting the activation of the NF‑κB pathway
Yu Zhang, Liyong Yuan, Yuebo Chen, Chunyan Lin, Guangyao Ye
Pages: 5223-5228 Published online on: 25 October 2019
Article
Genetic analysis of monoallelic double MYH7 mutations responsible for familial hypertrophic cardiomyopathy
Bo Wang, Jing Wang, Li‑Feng Wang, Fan Yang, Lei Xu, Wen‑Xia Li, Yang He, Lei Zuo, Qian‑Li Yang, Hong Shao, Dan Hu, Li‑Wen Liu
Pages: 5229-5238 Published online on: 16 October 2019
Article
Dynamic features of liver fibrogenesis and fibrosis resolution in the absence of matrix metalloproteinase‑9
Quanrongzi Wang, Xisheng Liu, Jie Zhang, Ling Lu, Min Feng, Jie Wang
Pages: 5239-5248 Published online on: 11 October 2019
Article
Gallotannin attenuates 2‑deoxy‑D‑glucose‑induced dedifferentiation and endoplasmic reticulum stress through inhibition of inositol‑requiring enzyme 1 downstream p38 kinase pathway in chondrocytes
Su Min Kim, Yohan Han, Seon‑Mi Yu, Song Ja Kim
Pages: 5249-5256 Published online on: 25 October 2019
Article
A simple, efficient and economical method for isolating and culturing human umbilical cord blood‑derived mesenchymal stromal cells
Junhe Zhang, Junli Zhao, Qinwen Mao, Haibin Xia
Pages: 5257-5264 Published online on: 23 October 2019
Article
BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice
Huifeng Yang, Haocong Zhang, Yu Li, Liangbi Xiang, Jun Liu
Pages: 5265-5271 Published online on: 30 October 2019
Article
Downregulation of miR‑138‑5p promotes non‑small cell lung cancer progression by regulating CDK8
Shigang Xing, Qinghua Xu, Xinlei Fan, Shanxia Wu, Feng Tian
Pages: 5272-5278 Published online on: 15 October 2019
Article
Effect of ethanol extracts of Hericium erinaceus mycelium on morphine‑induced microglial migration
Chung‑Hsin Yeh, Li‑Wei Sun, Chang‑Mei Lai, Tzu‑Pei Yeh, Jong‑Ni Lin, Shiow‑Luan Tsay, Chin‑Chu Chen, Wan‑Ping Chen, Chien‑Min Chen, Ru‑Yin Tsai
Pages: 5279-5285 Published online on: 15 October 2019
Article
ACSS2/AMPK/PCNA pathway‑driven proliferation and chemoresistance of esophageal squamous carcinoma cells under nutrient stress
Lei Mi, Yuepeng Zhou, Dan Wu, Qing Tao, Xuefeng Wang, Haitao Zhu, Xingyu Gao, Jingzhi Wang, Rui Ling, Jing Deng, Chaoming Mao, Deyu Chen
Pages: 5286-5296 Published online on: 09 October 2019
Article
Gene expression profiling analysis reveals that the long non‑coding RNA uc.412 is involved in mesangial cell proliferation
Minyi Yu, Zheng Guan, Shanwen Li, Xianli Wen, Huimin Shi, Gaoting Qu, Xiaoyu Lu, Xianyi Zhu, Bin Wang, Qihua Feng, Weihua Gan, Aiqing Zhang
Pages: 5297-5303 Published online on: 16 October 2019
Article
Prognostic implications of aberrantly expressed methylation‑driven genes in hepatocellular carcinoma: A study based on The Cancer Genome Atlas
Jinzhong Li, Ning Chen, Xiaobing Gong
Pages: 5304-5314 Published online on: 25 October 2019
Article
Dendritic cell exosome‑shuttled miRNA146a regulates exosome‑induced endothelial cell inflammation by inhibiting IRAK‑1: A feedback control mechanism
Xin Zhong, Wei Gao, Runda Wu, Haibo Liu, Junbo Ge
Pages: 5315-5323 Published online on: 16 October 2019
Article
Gene synthesizing, expression and immunogenicity characterization of recombinant translation elongation factor 2 from Dermatophagoides farinae
Desheng Chen, Qinghui Fu, Jianli Lin, Chengshen Hu, Nana Huang, Ke Xin Chang, Baoqing Sun, Zhigang Liu
Pages: 5324-5334 Published online on: 31 October 2019
Article
Gene targets of sulforaphane in head and neck squamous cell carcinoma
Lanlin Hu, Hua Li, Eliot D. Lee, Jennifer R. Grandis, Julie E. Bauman, Daniel E. Johnson
Pages: 5335-5344 Published online on: 23 October 2019
Article
Downregulation of FSTL‑1 attenuates the inflammation injury during Streptococcus pneumoniae infection by inhibiting the NLRP3 and TLR4/NF‑κB signaling pathway
Liang Chen, Zhenshe Liu
Pages: 5345-5352 Published online on: 16 October 2019
Article
Potential function of microRNAs in thoracic aortic aneurysm and thoracic aortic dissection pathogenesis
Tugce Senturk, Arzu Antal, Tuba Gunel
Pages: 5353-5362 Published online on: 22 October 2019
Correction