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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2019 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

HIV‑1 integrase inhibitors targeting various DDE transposases: Retroviral integration versus RAG‑mediated recombination (Review)

Mihaela Georgiana Mușat, George Mihai Nițulescu, Marius Surleac, Aristidis Tsatsakis, Demetrios A. Spandidos, Denisa Margină
Pages: 4749-4762
Published online on: 30 October 2019

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Review Open Access

Aryl hydrocarbon receptor pathway: Role, regulation and intervention in atherosclerosis therapy (Review)

Kaixi Zhu, Qingqi Meng, Zhi Zhang, Tao Yi, Yuan He, Jing Zheng, Wei Lei
Pages: 4763-4773
Published online on: 16 October 2019

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Review Open Access

Role of endoplasmic reticulum stress in depression (Review)

Jiaxin Mao, Yanran Hu, Liemin Ruan, Yunxin Ji, Zhongze Lou
Pages: 4774-4780
Published online on: 31 October 2019

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Article Open Access

miR‑455 targets FABP4 to protect human endometrial stromal cells from cytotoxicity induced by hydrogen peroxide

Wenbo Tang, Oujing Chen, Fengxiang Yao, Lining Cui
Pages: 4781-4790
Published online on: 04 October 2019

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Article Open Access

CXCR4 and CXCR3 are two distinct prognostic biomarkers in breast cancer: Database mining for CXCR family members

Kaibo Guo, Guan Feng, Qingying Yan, Leitao Sun, Kai Zhang, Fengfei Shen, Minhe Shen, Shanming Ruan
Pages: 4791-4802
Published online on: 30 October 2019

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Article Open Access

MicroRNA‑128‑b regulates epidermal growth factor receptor expression in non‑small cell lung cancer

Ling Li, Dongqing Wang
Pages: 4803-4810
Published online on: 08 October 2019

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Article Open Access

Effects of D‑Ala2, D‑Leu5‑Enkephalin pre‑ and post‑conditioning in a rabbit model of spinal cord ischemia and reperfusion injury

Danyun Fu, Haitong Liu, Hua Liu, Junyan Yao
Pages: 4811-4820
Published online on: 07 October 2019

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Article Open Access

Curcumin attenuates hypoxia/reoxygenation‑induced myocardial injury

Wenjuan Wei, Jun Peng, Jian Li
Pages: 4821-4830
Published online on: 15 October 2019

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Article Open Access

CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells

Min Zhang, Mei Gao, Jinyu Chen, Lihua Song, Wei Wei
Pages: 4831-4842
Published online on: 23 October 2019

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Article Open Access

miR‑760 regulates skeletal muscle proliferation in rheumatoid arthritis by targeting Myo18b

Xujun Tang, Jiuxia Wang, Shuhong Zhou, Jing Zhou, Guyou Jia, Han Wang, Chunlei Xin, Guoning Fu, Jiahong Zhang
Pages: 4843-4854
Published online on: 29 October 2019

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Article Open Access

Chloroquine promotes gefitinib‑induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma

Chengshan Ou, Hongxia Liu, Zhenhua Ding, Liang Zhou
Pages: 4855-4866
Published online on: 09 October 2019

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Article Open Access

Placental growth factor gene silencing mitigates the epithelial‑to‑mesenchymal transition via the p38 MAPK pathway in rats with hyperoxia‑induced lung injury

Shuang Zhao, Gang Luo, Hongmin Wu, Liang Zhang
Pages: 4867-4874
Published online on: 30 October 2019

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Article Open Access

miR‑222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl‑2

Wei Wang, Jian Wang, Jiayi Zhang, Wei Taq, Zhenxing Zhang
Pages: 4875-4882
Published online on: 09 October 2019

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Article Open Access

The JAK inhibitor tofacitinib ameliorates immune‑mediated liver injury in mice

Han Wang, Xinxia Feng, Ping Han, Yu Lei, Yujia Xia, Dean Tian, Wei Yan
Pages: 4883-4892
Published online on: 16 October 2019

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Article Open Access

Theaflavin attenuates cerebral ischemia/reperfusion injury by abolishing miRNA‑128‑3p‑mediated Nrf2 inhibition and reducing oxidative stress

Ronggang Li, Xin Li, Haibing Wu, Zhikun Yang, Li Fei, Jianhong Zhu
Pages: 4893-4904
Published online on: 17 October 2019

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Article Open Access

Whole‑exome sequencing in Russian children with non‑type 1 diabetes mellitus reveals a wide spectrum of genetic variants in MODY‑related and unrelated genes

Oleg S. Glotov, Elena A. Serebryakova, Mariia E. Turkunova, Olga A. Efimova, Andrey S. Glotov, Yury A. Barbitoff, Yulia A. Nasykhova, Alexander V. Predeus, Dmitrii E. Polev, Mikhail A. Fedyakov, Irina V. Polyakova, Tatyana E. Ivashchenko, Natalia Y. Shved, Elena S. Shabanova, Alena V. Tiselko, Olga V. Romanova, Andrey M. Sarana, Anna A. Pendina, Sergey G. Scherbak, Ekaterina V. Musina, Anastasiia V. Petrovskaia‑Kaminskaia, Liubov R. Lonishin, Liliya V. Ditkovskaya, Liudmila А. Zhelenina, Ludmila V. Tyrtova, Olga S. Berseneva, Rostislav K. Skitchenko, Evgenii N. Suspitsin, Elena B. Bashnina, Vladislav S. Baranov
Pages: 4905-4914
Published online on: 16 October 2019

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Article Open Access

Clinical and molecular characterization of four patients with NTCP deficiency from two unrelated families harboring the novel SLC10A1 variant c.595A>C (p.Ser199Arg)

Hua Li, Mei Deng, Li Guo, Jian‑Wu Qiu, Gui‑Zhi Lin, Xiao‑Ling Long, Xiao‑Min Xiao, Yuan‑Zong Song
Pages: 4915-4924
Published online on: 23 October 2019

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Article Open Access

Der p2‑A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis

Wenhui Hu, Li Ma, Gui Yang, Xianhai Zeng, Jiangqi Liu, Baohui Cheng, Tianyong Hu, Hailiang Zhao, Zhiqiang Liu
Pages: 4925-4932
Published online on: 21 October 2019

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Article Open Access

Exendin‑4 promotes osteogenic differentiation of adipose‑derived stem cells and facilitates bone repair

Banglian Deng, Wenzhong Zhu, Yansheng Duan, Yuqian Hu, Xuefeng Chen, Shuang Song, Zian Yi, Yingliang Song
Pages: 4933-4942
Published online on: 23 October 2019

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Article Open Access

Exopolysaccharide from Paecilomyces lilacinus modulates macrophage activities through the TLR4/NF‑κB/MAPK pathway

Chao He, Hai‑Yan Lin, Cai‑Chun Wang, Ming Zhang, Ying‑Ying Lin, Feng‑Ying Huang, Ying‑Zi Lin, Guang‑Hong Tan
Pages: 4943-4952
Published online on: 15 October 2019

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Article Open Access

miR‑21‑5p ameliorates hyperoxic acute lung injury and decreases apoptosis of AEC II cells via PTEN/AKT signaling in rats

Song Qin, Hongliang Wang, Guoyue Liu, Hong Mei, Miao Chen
Pages: 4953-4962
Published online on: 30 October 2019

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Article Open Access

Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF‑κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet

Qian Yu, Zhengyun Xia, Emily Chiu Liong, George Lim Tipoe
Pages: 4963-4972
Published online on: 31 October 2019

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Article Open Access

MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3 Retraction in /10.3892/mmr.2026.13814

Zhi‑Ying Li, Zi‑Zhou Zhang, Hui Bi, Qiu‑Di Zhang, Su‑Juan Zhang, Lin Zhou, Xiao‑Qin Zhu, Jun Zhou
Pages: 4973-4983
Published online on: 11 October 2019

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Article Open Access

Formononetin attenuates monocrotaline‑induced pulmonary arterial hypertension via inhibiting pulmonary vascular remodeling in rats

Changhong Cai, Yijia Xiang, Yonghui Wu, Ning Zhu, Huan Zhao, Jian Xu, Wensheng Lin, Chunlai Zeng
Pages: 4984-4992
Published online on: 30 October 2019

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Article Open Access

IL‑1β increases the expression of inflammatory factors in synovial fluid‑derived fibroblast‑like synoviocytes via activation of the NF‑κB‑mediated ERK‑STAT1 signaling pathway

Jie Yang, Junhu Wang, Xiaojun Liang, Hongmou Zhao, Jun Lu, Qiang Ma, Bingfei Jing, Feng Tian
Pages: 4993-5001
Published online on: 21 October 2019

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Article Open Access

Upregulation of miR‑132‑3p in cholangiocarcinoma tissues: A study based on RT‑qPCR, The Cancer Genome Atlas miRNA sequencing, Gene Expression Omnibus microarray data and bioinformatics analyses

Hua‑Yu Wu, Shuang Xia, An‑Gui Liu, Min‑Da Wei, Zhong‑Biao Chen, Yu‑Xin Li, Yu He, Min‑Jun Liao, Qi‑Ping Hu, Shang‑Ling Pan
Pages: 5002-5020
Published online on: 07 October 2019

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Article Open Access

SSTR5‑AS1 functions as a ceRNA to regulate CA2 by sponging miR‑15b‑5p for the development and prognosis of HBV‑related hepatocellular carcinoma

Jing Xu, Jing Zhang, Fenglian Shan, Jie Wen, Yue Wang
Pages: 5021-5031
Published online on: 11 October 2019

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Article Open Access

Curcumin relieves paraquat‑induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3‑mediated inflammatory pathway

Yi Ren, Zhizhou Yang, Zhaorui Sun, Wei Zhang, Xin Chen, Shinan Nie
Pages: 5032-5040
Published online on: 23 August 2019

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Article Open Access

Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a Retraction in /10.3892/mmr.2025.13747

Rui Li, Lianxin Wang
Pages: 5041-5049
Published online on: 15 October 2019

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Article Open Access

Effects of β‑hydroxybutyric acid and ghrelin on the motility and inflammation of gastric antral smooth muscle cells involving the regulation of growth hormone secretagogue receptor

Xiaolin Hu, Li You, Changhua Hu, Juan Wu, Min Ai, Xiaoyan He, Wenjie Huang, Zonghui Wu
Pages: 5050-5058
Published online on: 11 October 2019

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Article Open Access

Novel compound heterozygous PKHD1 mutations cause autosomal recessive polycystic kidney disease in a Han Chinese family

Jin Wang, Dandan Qi, Jialiang Yang, Dingding Zhang, Qingwei Wang, Xueming Ju, Xiang Zhong
Pages: 5059-5063
Published online on: 11 October 2019

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Article Open Access

Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line

Jing Han, Yonghong Tang, Meizuo Zhong, Wenlin Wu
Pages: 5064-5074
Published online on: 17 October 2019

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Article Open Access

Identification of dysregulated serum miR-508-3p and miR-885-5p as potential diagnostic biomarkers of clear cell renal carcinoma

Siming Liu, Xiaojun Deng, Jiong Zhang
Pages: 5075-5083
Published online on: 22 October 2019

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Article Open Access

High glucose inhibits osteogenic differentiation and proliferation of MC3T3‑E1 cells by regulating P2X7

Jinsan Yang, Cao Ma, Maoshu Zhang
Pages: 5084-5090
Published online on: 31 October 2019

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Article Open Access

C‑type natriuretic peptide prevents angiotensin II‑induced atrial connexin 40 and 43 dysregulation by activating AMP‑activated kinase signaling

Da‑Zhi Ding, Ya‑Nan Jia, Bo Zhang, Cheng‑Ming Guan, Shuai Zhou, Xiang Li, Xun Cui
Pages: 5091-5099
Published online on: 15 October 2019

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Article Open Access

Cannabinoid receptor 2‑selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord

Yanting Mao, Yulin Huang, Ying Zhang, Chenchen Wang, Hao Wu, Xinyu Tian, Yue Liu, Bailing Hou, Ying Liang, Hui Rong, Xiaoping Gu, Zhengliang Ma
Pages: 5100-5110
Published online on: 25 October 2019

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Article Open Access

Identification of whirlin domains interacting with espin: A study of the mechanism of Usher syndrome type II

Le Wang, Bo Wei, Xueqi Fu, Yuchen Wang, Yuan Sui, Junfeng Ma, Xianhui Gong, Jilong Hao, Shu Xing
Pages: 5111-5117
Published online on: 07 October 2019

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Case Report Open Access

Idiopathic renal hypouricemia: A case report and literature review

Cuiyu Wang, Jin Wang, Song Liu, Xinhua Liang, Yifan Song, Ling Feng, Lanxin Zhong, Xiaohua Guo
Pages: 5118-5124
Published online on: 04 October 2019

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Article Open Access

Effects of microRNA‑217 on high glucose‑induced inflammation and apoptosis of human retinal pigment epithelial cells (ARPE‑19) and its underlying mechanism

Hongxia Xiao, Zhen Liu
Pages: 5125-5133
Published online on: 30 October 2019

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Article Open Access

Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury

Junjie Wang, Dongdong Fu, Soulixay Senouthai, Yanwu You
Pages: 5134-5144
Published online on: 09 October 2019

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Article Open Access

Early‑onset epilepsy and microcephaly‑capillary malformation syndrome caused by a novel STAMBP mutation in a Chinese boy

Fangrui Wu, Ying Dai, Juan Wang, Min Cheng, Yanqin Wang, Xiujuan Li, Ping Yuan, Shuang Liao, Li Jiang, Jin Chen, Lisi Yan, Min Zhong
Pages: 5145-5151
Published online on: 17 October 2019

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Article Open Access

Effect of electrical stimulation combined with diet therapy on insulin resistance via mTOR signaling

Siqin Huang, Nianzhen Tang, Hongdi Zhao, Cheng‑Lin Tang
Pages: 5152-5162
Published online on: 30 October 2019

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Article Open Access

Nicotinamide phosphoribosyltransferase‑related signaling pathway in early Alzheimer's disease mouse models

Sanli Xing, Yiran Hu, Xujiao Huang, Dingzhu Shen, Chuan Chen
Pages: 5163-5171
Published online on: 30 October 2019

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Article Open Access

miR‑593 inhibits proliferation and invasion and promotes apoptosis in non‑small cell lung cancer cells by targeting SLUG‑associated signaling pathways Corrigendum in /10.3892/mmr.2021.12555 Retraction in /10.3892/mmr.2025.13490

Fang Wei, Mofei Wang, Zhen Li, Yong Wang, Yong Zhou
Pages: 5172-5182
Published online on: 29 October 2019

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Article Open Access

Dexmedetomidine improves cardiac function and protects against maladaptive remodeling following myocardial infarction

Hui Han, Daopeng Dai, Jinquan Hu, Jinzhou Zhu, Lin Lu, Guorong Tao, Ruiyan Zhang
Pages: 5183-5189
Published online on: 29 October 2019

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Article Open Access

Promotion of microglial phagocytosis by tuftsin stimulates remyelination in experimental autoimmune encephalomyelitis Corrigendum in /10.3892/mmr.2020.11042

Zheng Bao, Jinqi Hao, Yuhong Li, Fumin Feng
Pages: 5190-5196
Published online on: 31 October 2019

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Article Open Access

Kaempferol promotes bone formation in part via the mTOR signaling pathway

Jing Zhao, Jue Wu, Binwu Xu, Zhen Yuan, Yu Leng, Jun Min, Xiaoyong Lan, Jun Luo
Pages: 5197-5207
Published online on: 16 October 2019

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Article

miR‑486 acts as an oncogene and potential prognostic biomarker in renal cell carcinoma

Chengwen Sun, Caihong Sun, Yibin Zhou, Ganglong Yang, Guang Li, Congming Xiang, Xiqi Ding, Jian Sun
Pages: 5208-5215
Published online on: 25 October 2019

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Article

Long noncoding RNA MIAT: A potential role in the diagnosis and mediation of acute myocardial infarction

Mayra Azat, Xiaokelaiti Huojiahemaiti, Ranran Gao, Peng Peng
Pages: 5216-5222
Published online on: 23 October 2019

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Article

Oxyntomodulin attenuates TNF‑α induced neuropathic pain by inhibiting the activation of the NF‑κB pathway

Yu Zhang, Liyong Yuan, Yuebo Chen, Chunyan Lin, Guangyao Ye
Pages: 5223-5228
Published online on: 25 October 2019

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Article Open Access

Genetic analysis of monoallelic double MYH7 mutations responsible for familial hypertrophic cardiomyopathy

Bo Wang, Jing Wang, Li‑Feng Wang, Fan Yang, Lei Xu, Wen‑Xia Li, Yang He, Lei Zuo, Qian‑Li Yang, Hong Shao, Dan Hu, Li‑Wen Liu
Pages: 5229-5238
Published online on: 16 October 2019

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Article

Dynamic features of liver fibrogenesis and fibrosis resolution in the absence of matrix metalloproteinase‑9

Quanrongzi Wang, Xisheng Liu, Jie Zhang, Ling Lu, Min Feng, Jie Wang
Pages: 5239-5248
Published online on: 11 October 2019

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Article

Gallotannin attenuates 2‑deoxy‑D‑glucose‑induced dedifferentiation and endoplasmic reticulum stress through inhibition of inositol‑requiring enzyme 1 downstream p38 kinase pathway in chondrocytes

Su Min Kim, Yohan Han, Seon‑Mi Yu, Song Ja Kim
Pages: 5249-5256
Published online on: 25 October 2019

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Article

A simple, efficient and economical method for isolating and culturing human umbilical cord blood‑derived mesenchymal stromal cells

Junhe Zhang, Junli Zhao, Qinwen Mao, Haibin Xia
Pages: 5257-5264
Published online on: 23 October 2019

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Article

BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice

Huifeng Yang, Haocong Zhang, Yu Li, Liangbi Xiang, Jun Liu
Pages: 5265-5271
Published online on: 30 October 2019

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Article

Downregulation of miR‑138‑5p promotes non‑small cell lung cancer progression by regulating CDK8

Shigang Xing, Qinghua Xu, Xinlei Fan, Shanxia Wu, Feng Tian
Pages: 5272-5278
Published online on: 15 October 2019

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Article

Effect of ethanol extracts of Hericium erinaceus mycelium on morphine‑induced microglial migration

Chung‑Hsin Yeh, Li‑Wei Sun, Chang‑Mei Lai, Tzu‑Pei Yeh, Jong‑Ni Lin, Shiow‑Luan Tsay, Chin‑Chu Chen, Wan‑Ping Chen, Chien‑Min Chen, Ru‑Yin Tsai
Pages: 5279-5285
Published online on: 15 October 2019

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Article

ACSS2/AMPK/PCNA pathway‑driven proliferation and chemoresistance of esophageal squamous carcinoma cells under nutrient stress

Lei Mi, Yuepeng Zhou, Dan Wu, Qing Tao, Xuefeng Wang, Haitao Zhu, Xingyu Gao, Jingzhi Wang, Rui Ling, Jing Deng, Chaoming Mao, Deyu Chen
Pages: 5286-5296
Published online on: 09 October 2019

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Article Open Access

Gene expression profiling analysis reveals that the long non‑coding RNA uc.412 is involved in mesangial cell proliferation

Minyi Yu, Zheng Guan, Shanwen Li, Xianli Wen, Huimin Shi, Gaoting Qu, Xiaoyu Lu, Xianyi Zhu, Bin Wang, Qihua Feng, Weihua Gan, Aiqing Zhang
Pages: 5297-5303
Published online on: 16 October 2019

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Prognostic implications of aberrantly expressed methylation‑driven genes in hepatocellular carcinoma: A study based on The Cancer Genome Atlas

Jinzhong Li, Ning Chen, Xiaobing Gong
Pages: 5304-5314
Published online on: 25 October 2019

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Dendritic cell exosome‑shuttled miRNA146a regulates exosome‑induced endothelial cell inflammation by inhibiting IRAK‑1: A feedback control mechanism

Xin Zhong, Wei Gao, Runda Wu, Haibo Liu, Junbo Ge
Pages: 5315-5323
Published online on: 16 October 2019

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Gene synthesizing, expression and immunogenicity characterization of recombinant translation elongation factor 2 from Dermatophagoides farinae

Desheng Chen, Qinghui Fu, Jianli Lin, Chengshen Hu, Nana Huang, Ke Xin Chang, Baoqing Sun, Zhigang Liu
Pages: 5324-5334
Published online on: 31 October 2019

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Gene targets of sulforaphane in head and neck squamous cell carcinoma

Lanlin Hu, Hua Li, Eliot D. Lee, Jennifer R. Grandis, Julie E. Bauman, Daniel E. Johnson
Pages: 5335-5344
Published online on: 23 October 2019

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Downregulation of FSTL‑1 attenuates the inflammation injury during Streptococcus pneumoniae infection by inhibiting the NLRP3 and TLR4/NF‑κB signaling pathway

Liang Chen, Zhenshe Liu
Pages: 5345-5352
Published online on: 16 October 2019

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Potential function of microRNAs in thoracic aortic aneurysm and thoracic aortic dissection pathogenesis

Tugce Senturk, Arzu Antal, Tuba Gunel
Pages: 5353-5362
Published online on: 22 October 2019

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Correction Open Access

[Corrigendum] Differential miRNAomics of the synovial membrane in knee osteoarthritis induced by bilateral anterior cruciate ligament transection in rats

Jiangtao Zhou, Yina Zhao, Guangwen Wu, Bingbing Lin, Zuanfang Li, Xianxiang Liu
Pages: 5363-5363
Published online on: 18 October 2019

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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