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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2019 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

HIV‑1 integrase inhibitors targeting various DDE transposases: Retroviral integration versus RAG‑mediated recombination (Review)

Mihaela Georgiana Mușat, George Mihai Nițulescu, Marius Surleac, Aristidis Tsatsakis, Demetrios A. Spandidos, Denisa Margină
Pages: 4749-4762
Published online on: 30 October 2019

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Review Open Access

Aryl hydrocarbon receptor pathway: Role, regulation and intervention in atherosclerosis therapy (Review)

Kaixi Zhu, Qingqi Meng, Zhi Zhang, Tao Yi, Yuan He, Jing Zheng, Wei Lei
Pages: 4763-4773
Published online on: 16 October 2019

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Review Open Access

Role of endoplasmic reticulum stress in depression (Review)

Jiaxin Mao, Yanran Hu, Liemin Ruan, Yunxin Ji, Zhongze Lou
Pages: 4774-4780
Published online on: 31 October 2019

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Article Open Access

miR‑455 targets FABP4 to protect human endometrial stromal cells from cytotoxicity induced by hydrogen peroxide

Wenbo Tang, Oujing Chen, Fengxiang Yao, Lining Cui
Pages: 4781-4790
Published online on: 04 October 2019

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Article Open Access

CXCR4 and CXCR3 are two distinct prognostic biomarkers in breast cancer: Database mining for CXCR family members

Kaibo Guo, Guan Feng, Qingying Yan, Leitao Sun, Kai Zhang, Fengfei Shen, Minhe Shen, Shanming Ruan
Pages: 4791-4802
Published online on: 30 October 2019

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Article Open Access

MicroRNA‑128‑b regulates epidermal growth factor receptor expression in non‑small cell lung cancer

Ling Li, Dongqing Wang
Pages: 4803-4810
Published online on: 08 October 2019

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Article Open Access

Effects of D‑Ala2, D‑Leu5‑Enkephalin pre‑ and post‑conditioning in a rabbit model of spinal cord ischemia and reperfusion injury

Danyun Fu, Haitong Liu, Hua Liu, Junyan Yao
Pages: 4811-4820
Published online on: 07 October 2019

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Article Open Access

Curcumin attenuates hypoxia/reoxygenation‑induced myocardial injury

Wenjuan Wei, Jun Peng, Jian Li
Pages: 4821-4830
Published online on: 15 October 2019

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Article Open Access

CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells

Min Zhang, Mei Gao, Jinyu Chen, Lihua Song, Wei Wei
Pages: 4831-4842
Published online on: 23 October 2019

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Article Open Access

miR‑760 regulates skeletal muscle proliferation in rheumatoid arthritis by targeting Myo18b

Xujun Tang, Jiuxia Wang, Shuhong Zhou, Jing Zhou, Guyou Jia, Han Wang, Chunlei Xin, Guoning Fu, Jiahong Zhang
Pages: 4843-4854
Published online on: 29 October 2019

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Article Open Access

Chloroquine promotes gefitinib‑induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma

Chengshan Ou, Hongxia Liu, Zhenhua Ding, Liang Zhou
Pages: 4855-4866
Published online on: 09 October 2019

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Article Open Access

Placental growth factor gene silencing mitigates the epithelial‑to‑mesenchymal transition via the p38 MAPK pathway in rats with hyperoxia‑induced lung injury

Shuang Zhao, Gang Luo, Hongmin Wu, Liang Zhang
Pages: 4867-4874
Published online on: 30 October 2019

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Article Open Access

miR‑222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl‑2

Wei Wang, Jian Wang, Jiayi Zhang, Wei Taq, Zhenxing Zhang
Pages: 4875-4882
Published online on: 09 October 2019

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Article Open Access

The JAK inhibitor tofacitinib ameliorates immune‑mediated liver injury in mice

Han Wang, Xinxia Feng, Ping Han, Yu Lei, Yujia Xia, Dean Tian, Wei Yan
Pages: 4883-4892
Published online on: 16 October 2019

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Article Open Access

Theaflavin attenuates cerebral ischemia/reperfusion injury by abolishing miRNA‑128‑3p‑mediated Nrf2 inhibition and reducing oxidative stress

Ronggang Li, Xin Li, Haibing Wu, Zhikun Yang, Li Fei, Jianhong Zhu
Pages: 4893-4904
Published online on: 17 October 2019

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Article Open Access

Whole‑exome sequencing in Russian children with non‑type 1 diabetes mellitus reveals a wide spectrum of genetic variants in MODY‑related and unrelated genes

Oleg S. Glotov, Elena A. Serebryakova, Mariia E. Turkunova, Olga A. Efimova, Andrey S. Glotov, Yury A. Barbitoff, Yulia A. Nasykhova, Alexander V. Predeus, Dmitrii E. Polev, Mikhail A. Fedyakov, Irina V. Polyakova, Tatyana E. Ivashchenko, Natalia Y. Shved, Elena S. Shabanova, Alena V. Tiselko, Olga V. Romanova, Andrey M. Sarana, Anna A. Pendina, Sergey G. Scherbak, Ekaterina V. Musina, Anastasiia V. Petrovskaia‑Kaminskaia, Liubov R. Lonishin, Liliya V. Ditkovskaya, Liudmila А. Zhelenina, Ludmila V. Tyrtova, Olga S. Berseneva, Rostislav K. Skitchenko, Evgenii N. Suspitsin, Elena B. Bashnina, Vladislav S. Baranov
Pages: 4905-4914
Published online on: 16 October 2019

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Article Open Access

Clinical and molecular characterization of four patients with NTCP deficiency from two unrelated families harboring the novel SLC10A1 variant c.595A>C (p.Ser199Arg)

Hua Li, Mei Deng, Li Guo, Jian‑Wu Qiu, Gui‑Zhi Lin, Xiao‑Ling Long, Xiao‑Min Xiao, Yuan‑Zong Song
Pages: 4915-4924
Published online on: 23 October 2019

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Article Open Access

Der p2‑A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis

Wenhui Hu, Li Ma, Gui Yang, Xianhai Zeng, Jiangqi Liu, Baohui Cheng, Tianyong Hu, Hailiang Zhao, Zhiqiang Liu
Pages: 4925-4932
Published online on: 21 October 2019

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Article Open Access

Exendin‑4 promotes osteogenic differentiation of adipose‑derived stem cells and facilitates bone repair

Banglian Deng, Wenzhong Zhu, Yansheng Duan, Yuqian Hu, Xuefeng Chen, Shuang Song, Zian Yi, Yingliang Song
Pages: 4933-4942
Published online on: 23 October 2019

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Article Open Access

Exopolysaccharide from Paecilomyces lilacinus modulates macrophage activities through the TLR4/NF‑κB/MAPK pathway

Chao He, Hai‑Yan Lin, Cai‑Chun Wang, Ming Zhang, Ying‑Ying Lin, Feng‑Ying Huang, Ying‑Zi Lin, Guang‑Hong Tan
Pages: 4943-4952
Published online on: 15 October 2019

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Article Open Access

miR‑21‑5p ameliorates hyperoxic acute lung injury and decreases apoptosis of AEC II cells via PTEN/AKT signaling in rats

Song Qin, Hongliang Wang, Guoyue Liu, Hong Mei, Miao Chen
Pages: 4953-4962
Published online on: 30 October 2019

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Article Open Access

Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF‑κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet

Qian Yu, Zhengyun Xia, Emily Chiu Liong, George Lim Tipoe
Pages: 4963-4972
Published online on: 31 October 2019

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Article Open Access

MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3 Retraction in /10.3892/mmr.2026.13814

Zhi‑Ying Li, Zi‑Zhou Zhang, Hui Bi, Qiu‑Di Zhang, Su‑Juan Zhang, Lin Zhou, Xiao‑Qin Zhu, Jun Zhou
Pages: 4973-4983
Published online on: 11 October 2019

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Article Open Access

Formononetin attenuates monocrotaline‑induced pulmonary arterial hypertension via inhibiting pulmonary vascular remodeling in rats

Changhong Cai, Yijia Xiang, Yonghui Wu, Ning Zhu, Huan Zhao, Jian Xu, Wensheng Lin, Chunlai Zeng
Pages: 4984-4992
Published online on: 30 October 2019

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Article Open Access

IL‑1β increases the expression of inflammatory factors in synovial fluid‑derived fibroblast‑like synoviocytes via activation of the NF‑κB‑mediated ERK‑STAT1 signaling pathway

Jie Yang, Junhu Wang, Xiaojun Liang, Hongmou Zhao, Jun Lu, Qiang Ma, Bingfei Jing, Feng Tian
Pages: 4993-5001
Published online on: 21 October 2019

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Article Open Access

Upregulation of miR‑132‑3p in cholangiocarcinoma tissues: A study based on RT‑qPCR, The Cancer Genome Atlas miRNA sequencing, Gene Expression Omnibus microarray data and bioinformatics analyses

Hua‑Yu Wu, Shuang Xia, An‑Gui Liu, Min‑Da Wei, Zhong‑Biao Chen, Yu‑Xin Li, Yu He, Min‑Jun Liao, Qi‑Ping Hu, Shang‑Ling Pan
Pages: 5002-5020
Published online on: 07 October 2019

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Article Open Access

SSTR5‑AS1 functions as a ceRNA to regulate CA2 by sponging miR‑15b‑5p for the development and prognosis of HBV‑related hepatocellular carcinoma

Jing Xu, Jing Zhang, Fenglian Shan, Jie Wen, Yue Wang
Pages: 5021-5031
Published online on: 11 October 2019

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Article Open Access

Curcumin relieves paraquat‑induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3‑mediated inflammatory pathway

Yi Ren, Zhizhou Yang, Zhaorui Sun, Wei Zhang, Xin Chen, Shinan Nie
Pages: 5032-5040
Published online on: 23 August 2019

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Article Open Access

Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a Retraction in /10.3892/mmr.2025.13747

Rui Li, Lianxin Wang
Pages: 5041-5049
Published online on: 15 October 2019

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Article Open Access

Effects of β‑hydroxybutyric acid and ghrelin on the motility and inflammation of gastric antral smooth muscle cells involving the regulation of growth hormone secretagogue receptor

Xiaolin Hu, Li You, Changhua Hu, Juan Wu, Min Ai, Xiaoyan He, Wenjie Huang, Zonghui Wu
Pages: 5050-5058
Published online on: 11 October 2019

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Article Open Access

Novel compound heterozygous PKHD1 mutations cause autosomal recessive polycystic kidney disease in a Han Chinese family

Jin Wang, Dandan Qi, Jialiang Yang, Dingding Zhang, Qingwei Wang, Xueming Ju, Xiang Zhong
Pages: 5059-5063
Published online on: 11 October 2019

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Article Open Access

Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line

Jing Han, Yonghong Tang, Meizuo Zhong, Wenlin Wu
Pages: 5064-5074
Published online on: 17 October 2019

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Article Open Access

Identification of dysregulated serum miR-508-3p and miR-885-5p as potential diagnostic biomarkers of clear cell renal carcinoma

Siming Liu, Xiaojun Deng, Jiong Zhang
Pages: 5075-5083
Published online on: 22 October 2019

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Article Open Access

High glucose inhibits osteogenic differentiation and proliferation of MC3T3‑E1 cells by regulating P2X7

Jinsan Yang, Cao Ma, Maoshu Zhang
Pages: 5084-5090
Published online on: 31 October 2019

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Article Open Access

C‑type natriuretic peptide prevents angiotensin II‑induced atrial connexin 40 and 43 dysregulation by activating AMP‑activated kinase signaling

Da‑Zhi Ding, Ya‑Nan Jia, Bo Zhang, Cheng‑Ming Guan, Shuai Zhou, Xiang Li, Xun Cui
Pages: 5091-5099
Published online on: 15 October 2019

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Article Open Access

Cannabinoid receptor 2‑selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord

Yanting Mao, Yulin Huang, Ying Zhang, Chenchen Wang, Hao Wu, Xinyu Tian, Yue Liu, Bailing Hou, Ying Liang, Hui Rong, Xiaoping Gu, Zhengliang Ma
Pages: 5100-5110
Published online on: 25 October 2019

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Article Open Access

Identification of whirlin domains interacting with espin: A study of the mechanism of Usher syndrome type II

Le Wang, Bo Wei, Xueqi Fu, Yuchen Wang, Yuan Sui, Junfeng Ma, Xianhui Gong, Jilong Hao, Shu Xing
Pages: 5111-5117
Published online on: 07 October 2019

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Case Report Open Access

Idiopathic renal hypouricemia: A case report and literature review

Cuiyu Wang, Jin Wang, Song Liu, Xinhua Liang, Yifan Song, Ling Feng, Lanxin Zhong, Xiaohua Guo
Pages: 5118-5124
Published online on: 04 October 2019

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Article Open Access

Effects of microRNA‑217 on high glucose‑induced inflammation and apoptosis of human retinal pigment epithelial cells (ARPE‑19) and its underlying mechanism

Hongxia Xiao, Zhen Liu
Pages: 5125-5133
Published online on: 30 October 2019

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Article Open Access

Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury

Junjie Wang, Dongdong Fu, Soulixay Senouthai, Yanwu You
Pages: 5134-5144
Published online on: 09 October 2019

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Article Open Access

Early‑onset epilepsy and microcephaly‑capillary malformation syndrome caused by a novel STAMBP mutation in a Chinese boy

Fangrui Wu, Ying Dai, Juan Wang, Min Cheng, Yanqin Wang, Xiujuan Li, Ping Yuan, Shuang Liao, Li Jiang, Jin Chen, Lisi Yan, Min Zhong
Pages: 5145-5151
Published online on: 17 October 2019

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Article Open Access

Effect of electrical stimulation combined with diet therapy on insulin resistance via mTOR signaling

Siqin Huang, Nianzhen Tang, Hongdi Zhao, Cheng‑Lin Tang
Pages: 5152-5162
Published online on: 30 October 2019

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Article Open Access

Nicotinamide phosphoribosyltransferase‑related signaling pathway in early Alzheimer's disease mouse models

Sanli Xing, Yiran Hu, Xujiao Huang, Dingzhu Shen, Chuan Chen
Pages: 5163-5171
Published online on: 30 October 2019

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Article Open Access

miR‑593 inhibits proliferation and invasion and promotes apoptosis in non‑small cell lung cancer cells by targeting SLUG‑associated signaling pathways Corrigendum in /10.3892/mmr.2021.12555 Retraction in /10.3892/mmr.2025.13490

Fang Wei, Mofei Wang, Zhen Li, Yong Wang, Yong Zhou
Pages: 5172-5182
Published online on: 29 October 2019

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Article Open Access

Dexmedetomidine improves cardiac function and protects against maladaptive remodeling following myocardial infarction

Hui Han, Daopeng Dai, Jinquan Hu, Jinzhou Zhu, Lin Lu, Guorong Tao, Ruiyan Zhang
Pages: 5183-5189
Published online on: 29 October 2019

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Article Open Access

Promotion of microglial phagocytosis by tuftsin stimulates remyelination in experimental autoimmune encephalomyelitis Corrigendum in /10.3892/mmr.2020.11042

Zheng Bao, Jinqi Hao, Yuhong Li, Fumin Feng
Pages: 5190-5196
Published online on: 31 October 2019

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Article Open Access

Kaempferol promotes bone formation in part via the mTOR signaling pathway

Jing Zhao, Jue Wu, Binwu Xu, Zhen Yuan, Yu Leng, Jun Min, Xiaoyong Lan, Jun Luo
Pages: 5197-5207
Published online on: 16 October 2019

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Article

miR‑486 acts as an oncogene and potential prognostic biomarker in renal cell carcinoma

Chengwen Sun, Caihong Sun, Yibin Zhou, Ganglong Yang, Guang Li, Congming Xiang, Xiqi Ding, Jian Sun
Pages: 5208-5215
Published online on: 25 October 2019

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Article

Long noncoding RNA MIAT: A potential role in the diagnosis and mediation of acute myocardial infarction

Mayra Azat, Xiaokelaiti Huojiahemaiti, Ranran Gao, Peng Peng
Pages: 5216-5222
Published online on: 23 October 2019

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Article

Oxyntomodulin attenuates TNF‑α induced neuropathic pain by inhibiting the activation of the NF‑κB pathway

Yu Zhang, Liyong Yuan, Yuebo Chen, Chunyan Lin, Guangyao Ye
Pages: 5223-5228
Published online on: 25 October 2019

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Article Open Access

Genetic analysis of monoallelic double MYH7 mutations responsible for familial hypertrophic cardiomyopathy

Bo Wang, Jing Wang, Li‑Feng Wang, Fan Yang, Lei Xu, Wen‑Xia Li, Yang He, Lei Zuo, Qian‑Li Yang, Hong Shao, Dan Hu, Li‑Wen Liu
Pages: 5229-5238
Published online on: 16 October 2019

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Article

Dynamic features of liver fibrogenesis and fibrosis resolution in the absence of matrix metalloproteinase‑9

Quanrongzi Wang, Xisheng Liu, Jie Zhang, Ling Lu, Min Feng, Jie Wang
Pages: 5239-5248
Published online on: 11 October 2019

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Article

Gallotannin attenuates 2‑deoxy‑D‑glucose‑induced dedifferentiation and endoplasmic reticulum stress through inhibition of inositol‑requiring enzyme 1 downstream p38 kinase pathway in chondrocytes

Su Min Kim, Yohan Han, Seon‑Mi Yu, Song Ja Kim
Pages: 5249-5256
Published online on: 25 October 2019

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Article

A simple, efficient and economical method for isolating and culturing human umbilical cord blood‑derived mesenchymal stromal cells

Junhe Zhang, Junli Zhao, Qinwen Mao, Haibin Xia
Pages: 5257-5264
Published online on: 23 October 2019

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Article

BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice

Huifeng Yang, Haocong Zhang, Yu Li, Liangbi Xiang, Jun Liu
Pages: 5265-5271
Published online on: 30 October 2019

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Article

Downregulation of miR‑138‑5p promotes non‑small cell lung cancer progression by regulating CDK8

Shigang Xing, Qinghua Xu, Xinlei Fan, Shanxia Wu, Feng Tian
Pages: 5272-5278
Published online on: 15 October 2019

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Article

Effect of ethanol extracts of Hericium erinaceus mycelium on morphine‑induced microglial migration

Chung‑Hsin Yeh, Li‑Wei Sun, Chang‑Mei Lai, Tzu‑Pei Yeh, Jong‑Ni Lin, Shiow‑Luan Tsay, Chin‑Chu Chen, Wan‑Ping Chen, Chien‑Min Chen, Ru‑Yin Tsai
Pages: 5279-5285
Published online on: 15 October 2019

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Article

ACSS2/AMPK/PCNA pathway‑driven proliferation and chemoresistance of esophageal squamous carcinoma cells under nutrient stress

Lei Mi, Yuepeng Zhou, Dan Wu, Qing Tao, Xuefeng Wang, Haitao Zhu, Xingyu Gao, Jingzhi Wang, Rui Ling, Jing Deng, Chaoming Mao, Deyu Chen
Pages: 5286-5296
Published online on: 09 October 2019

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Article Open Access

Gene expression profiling analysis reveals that the long non‑coding RNA uc.412 is involved in mesangial cell proliferation

Minyi Yu, Zheng Guan, Shanwen Li, Xianli Wen, Huimin Shi, Gaoting Qu, Xiaoyu Lu, Xianyi Zhu, Bin Wang, Qihua Feng, Weihua Gan, Aiqing Zhang
Pages: 5297-5303
Published online on: 16 October 2019

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Prognostic implications of aberrantly expressed methylation‑driven genes in hepatocellular carcinoma: A study based on The Cancer Genome Atlas

Jinzhong Li, Ning Chen, Xiaobing Gong
Pages: 5304-5314
Published online on: 25 October 2019

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Dendritic cell exosome‑shuttled miRNA146a regulates exosome‑induced endothelial cell inflammation by inhibiting IRAK‑1: A feedback control mechanism

Xin Zhong, Wei Gao, Runda Wu, Haibo Liu, Junbo Ge
Pages: 5315-5323
Published online on: 16 October 2019

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Gene synthesizing, expression and immunogenicity characterization of recombinant translation elongation factor 2 from Dermatophagoides farinae

Desheng Chen, Qinghui Fu, Jianli Lin, Chengshen Hu, Nana Huang, Ke Xin Chang, Baoqing Sun, Zhigang Liu
Pages: 5324-5334
Published online on: 31 October 2019

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Gene targets of sulforaphane in head and neck squamous cell carcinoma

Lanlin Hu, Hua Li, Eliot D. Lee, Jennifer R. Grandis, Julie E. Bauman, Daniel E. Johnson
Pages: 5335-5344
Published online on: 23 October 2019

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Downregulation of FSTL‑1 attenuates the inflammation injury during Streptococcus pneumoniae infection by inhibiting the NLRP3 and TLR4/NF‑κB signaling pathway

Liang Chen, Zhenshe Liu
Pages: 5345-5352
Published online on: 16 October 2019

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Potential function of microRNAs in thoracic aortic aneurysm and thoracic aortic dissection pathogenesis

Tugce Senturk, Arzu Antal, Tuba Gunel
Pages: 5353-5362
Published online on: 22 October 2019

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Correction Open Access

[Corrigendum] Differential miRNAomics of the synovial membrane in knee osteoarthritis induced by bilateral anterior cruciate ligament transection in rats

Jiangtao Zhou, Yina Zhao, Guangwen Wu, Bingbing Lin, Zuanfang Li, Xianxiang Liu
Pages: 5363-5363
Published online on: 18 October 2019

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July-2026 Volume 34 Issue 1

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Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 34 Issue 2

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Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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