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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2019 Volume 20 Issue 6

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

HIV‑1 integrase inhibitors targeting various DDE transposases: Retroviral integration versus RAG‑mediated recombination (Review)

Mihaela Georgiana Mușat, George Mihai Nițulescu, Marius Surleac, Aristidis Tsatsakis, Demetrios A. Spandidos, Denisa Margină
Pages: 4749-4762
Published online on: 30 October 2019

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Review Open Access

Aryl hydrocarbon receptor pathway: Role, regulation and intervention in atherosclerosis therapy (Review)

Kaixi Zhu, Qingqi Meng, Zhi Zhang, Tao Yi, Yuan He, Jing Zheng, Wei Lei
Pages: 4763-4773
Published online on: 16 October 2019

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Review Open Access

Role of endoplasmic reticulum stress in depression (Review)

Jiaxin Mao, Yanran Hu, Liemin Ruan, Yunxin Ji, Zhongze Lou
Pages: 4774-4780
Published online on: 31 October 2019

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Article Open Access

miR‑455 targets FABP4 to protect human endometrial stromal cells from cytotoxicity induced by hydrogen peroxide

Wenbo Tang, Oujing Chen, Fengxiang Yao, Lining Cui
Pages: 4781-4790
Published online on: 04 October 2019

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Article Open Access

CXCR4 and CXCR3 are two distinct prognostic biomarkers in breast cancer: Database mining for CXCR family members

Kaibo Guo, Guan Feng, Qingying Yan, Leitao Sun, Kai Zhang, Fengfei Shen, Minhe Shen, Shanming Ruan
Pages: 4791-4802
Published online on: 30 October 2019

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Article Open Access

MicroRNA‑128‑b regulates epidermal growth factor receptor expression in non‑small cell lung cancer

Ling Li, Dongqing Wang
Pages: 4803-4810
Published online on: 08 October 2019

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Article Open Access

Effects of D‑Ala2, D‑Leu5‑Enkephalin pre‑ and post‑conditioning in a rabbit model of spinal cord ischemia and reperfusion injury

Danyun Fu, Haitong Liu, Hua Liu, Junyan Yao
Pages: 4811-4820
Published online on: 07 October 2019

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Article Open Access

Curcumin attenuates hypoxia/reoxygenation‑induced myocardial injury

Wenjuan Wei, Jun Peng, Jian Li
Pages: 4821-4830
Published online on: 15 October 2019

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Article Open Access

CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells

Min Zhang, Mei Gao, Jinyu Chen, Lihua Song, Wei Wei
Pages: 4831-4842
Published online on: 23 October 2019

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Article Open Access

miR‑760 regulates skeletal muscle proliferation in rheumatoid arthritis by targeting Myo18b

Xujun Tang, Jiuxia Wang, Shuhong Zhou, Jing Zhou, Guyou Jia, Han Wang, Chunlei Xin, Guoning Fu, Jiahong Zhang
Pages: 4843-4854
Published online on: 29 October 2019

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Article Open Access

Chloroquine promotes gefitinib‑induced apoptosis by inhibiting protective autophagy in cutaneous squamous cell carcinoma

Chengshan Ou, Hongxia Liu, Zhenhua Ding, Liang Zhou
Pages: 4855-4866
Published online on: 09 October 2019

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Article Open Access

Placental growth factor gene silencing mitigates the epithelial‑to‑mesenchymal transition via the p38 MAPK pathway in rats with hyperoxia‑induced lung injury

Shuang Zhao, Gang Luo, Hongmin Wu, Liang Zhang
Pages: 4867-4874
Published online on: 30 October 2019

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Article Open Access

miR‑222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl‑2

Wei Wang, Jian Wang, Jiayi Zhang, Wei Taq, Zhenxing Zhang
Pages: 4875-4882
Published online on: 09 October 2019

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Article Open Access

The JAK inhibitor tofacitinib ameliorates immune‑mediated liver injury in mice

Han Wang, Xinxia Feng, Ping Han, Yu Lei, Yujia Xia, Dean Tian, Wei Yan
Pages: 4883-4892
Published online on: 16 October 2019

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Article Open Access

Theaflavin attenuates cerebral ischemia/reperfusion injury by abolishing miRNA‑128‑3p‑mediated Nrf2 inhibition and reducing oxidative stress

Ronggang Li, Xin Li, Haibing Wu, Zhikun Yang, Li Fei, Jianhong Zhu
Pages: 4893-4904
Published online on: 17 October 2019

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Article Open Access

Whole‑exome sequencing in Russian children with non‑type 1 diabetes mellitus reveals a wide spectrum of genetic variants in MODY‑related and unrelated genes

Oleg S. Glotov, Elena A. Serebryakova, Mariia E. Turkunova, Olga A. Efimova, Andrey S. Glotov, Yury A. Barbitoff, Yulia A. Nasykhova, Alexander V. Predeus, Dmitrii E. Polev, Mikhail A. Fedyakov, Irina V. Polyakova, Tatyana E. Ivashchenko, Natalia Y. Shved, Elena S. Shabanova, Alena V. Tiselko, Olga V. Romanova, Andrey M. Sarana, Anna A. Pendina, Sergey G. Scherbak, Ekaterina V. Musina, Anastasiia V. Petrovskaia‑Kaminskaia, Liubov R. Lonishin, Liliya V. Ditkovskaya, Liudmila А. Zhelenina, Ludmila V. Tyrtova, Olga S. Berseneva, Rostislav K. Skitchenko, Evgenii N. Suspitsin, Elena B. Bashnina, Vladislav S. Baranov
Pages: 4905-4914
Published online on: 16 October 2019

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Article Open Access

Clinical and molecular characterization of four patients with NTCP deficiency from two unrelated families harboring the novel SLC10A1 variant c.595A>C (p.Ser199Arg)

Hua Li, Mei Deng, Li Guo, Jian‑Wu Qiu, Gui‑Zhi Lin, Xiao‑Ling Long, Xiao‑Min Xiao, Yuan‑Zong Song
Pages: 4915-4924
Published online on: 23 October 2019

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Article Open Access

Der p2‑A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis

Wenhui Hu, Li Ma, Gui Yang, Xianhai Zeng, Jiangqi Liu, Baohui Cheng, Tianyong Hu, Hailiang Zhao, Zhiqiang Liu
Pages: 4925-4932
Published online on: 21 October 2019

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Article Open Access

Exendin‑4 promotes osteogenic differentiation of adipose‑derived stem cells and facilitates bone repair

Banglian Deng, Wenzhong Zhu, Yansheng Duan, Yuqian Hu, Xuefeng Chen, Shuang Song, Zian Yi, Yingliang Song
Pages: 4933-4942
Published online on: 23 October 2019

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Article Open Access

Exopolysaccharide from Paecilomyces lilacinus modulates macrophage activities through the TLR4/NF‑κB/MAPK pathway

Chao He, Hai‑Yan Lin, Cai‑Chun Wang, Ming Zhang, Ying‑Ying Lin, Feng‑Ying Huang, Ying‑Zi Lin, Guang‑Hong Tan
Pages: 4943-4952
Published online on: 15 October 2019

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Article Open Access

miR‑21‑5p ameliorates hyperoxic acute lung injury and decreases apoptosis of AEC II cells via PTEN/AKT signaling in rats

Song Qin, Hongliang Wang, Guoyue Liu, Hong Mei, Miao Chen
Pages: 4953-4962
Published online on: 30 October 2019

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Article Open Access

Chronic aerobic exercise improves insulin sensitivity and modulates Nrf2 and NF‑κB/IκBα pathways in the skeletal muscle of rats fed with a high fat diet

Qian Yu, Zhengyun Xia, Emily Chiu Liong, George Lim Tipoe
Pages: 4963-4972
Published online on: 31 October 2019

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Article Open Access

MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3 Retraction in /10.3892/mmr.2026.13814

Zhi‑Ying Li, Zi‑Zhou Zhang, Hui Bi, Qiu‑Di Zhang, Su‑Juan Zhang, Lin Zhou, Xiao‑Qin Zhu, Jun Zhou
Pages: 4973-4983
Published online on: 11 October 2019

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Article Open Access

Formononetin attenuates monocrotaline‑induced pulmonary arterial hypertension via inhibiting pulmonary vascular remodeling in rats

Changhong Cai, Yijia Xiang, Yonghui Wu, Ning Zhu, Huan Zhao, Jian Xu, Wensheng Lin, Chunlai Zeng
Pages: 4984-4992
Published online on: 30 October 2019

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Article Open Access

IL‑1β increases the expression of inflammatory factors in synovial fluid‑derived fibroblast‑like synoviocytes via activation of the NF‑κB‑mediated ERK‑STAT1 signaling pathway

Jie Yang, Junhu Wang, Xiaojun Liang, Hongmou Zhao, Jun Lu, Qiang Ma, Bingfei Jing, Feng Tian
Pages: 4993-5001
Published online on: 21 October 2019

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Article Open Access

Upregulation of miR‑132‑3p in cholangiocarcinoma tissues: A study based on RT‑qPCR, The Cancer Genome Atlas miRNA sequencing, Gene Expression Omnibus microarray data and bioinformatics analyses

Hua‑Yu Wu, Shuang Xia, An‑Gui Liu, Min‑Da Wei, Zhong‑Biao Chen, Yu‑Xin Li, Yu He, Min‑Jun Liao, Qi‑Ping Hu, Shang‑Ling Pan
Pages: 5002-5020
Published online on: 07 October 2019

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Article Open Access

SSTR5‑AS1 functions as a ceRNA to regulate CA2 by sponging miR‑15b‑5p for the development and prognosis of HBV‑related hepatocellular carcinoma

Jing Xu, Jing Zhang, Fenglian Shan, Jie Wen, Yue Wang
Pages: 5021-5031
Published online on: 11 October 2019

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Article Open Access

Curcumin relieves paraquat‑induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3‑mediated inflammatory pathway

Yi Ren, Zhizhou Yang, Zhaorui Sun, Wei Zhang, Xin Chen, Shinan Nie
Pages: 5032-5040
Published online on: 23 August 2019

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Article Open Access

Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a Retraction in /10.3892/mmr.2025.13747

Rui Li, Lianxin Wang
Pages: 5041-5049
Published online on: 15 October 2019

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Article Open Access

Effects of β‑hydroxybutyric acid and ghrelin on the motility and inflammation of gastric antral smooth muscle cells involving the regulation of growth hormone secretagogue receptor

Xiaolin Hu, Li You, Changhua Hu, Juan Wu, Min Ai, Xiaoyan He, Wenjie Huang, Zonghui Wu
Pages: 5050-5058
Published online on: 11 October 2019

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Article Open Access

Novel compound heterozygous PKHD1 mutations cause autosomal recessive polycystic kidney disease in a Han Chinese family

Jin Wang, Dandan Qi, Jialiang Yang, Dingding Zhang, Qingwei Wang, Xueming Ju, Xiang Zhong
Pages: 5059-5063
Published online on: 11 October 2019

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Article Open Access

Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line

Jing Han, Yonghong Tang, Meizuo Zhong, Wenlin Wu
Pages: 5064-5074
Published online on: 17 October 2019

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Article Open Access

Identification of dysregulated serum miR-508-3p and miR-885-5p as potential diagnostic biomarkers of clear cell renal carcinoma

Siming Liu, Xiaojun Deng, Jiong Zhang
Pages: 5075-5083
Published online on: 22 October 2019

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Article Open Access

High glucose inhibits osteogenic differentiation and proliferation of MC3T3‑E1 cells by regulating P2X7

Jinsan Yang, Cao Ma, Maoshu Zhang
Pages: 5084-5090
Published online on: 31 October 2019

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Article Open Access

C‑type natriuretic peptide prevents angiotensin II‑induced atrial connexin 40 and 43 dysregulation by activating AMP‑activated kinase signaling

Da‑Zhi Ding, Ya‑Nan Jia, Bo Zhang, Cheng‑Ming Guan, Shuai Zhou, Xiang Li, Xun Cui
Pages: 5091-5099
Published online on: 15 October 2019

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Article Open Access

Cannabinoid receptor 2‑selective agonist JWH015 attenuates bone cancer pain through the amelioration of impaired autophagy flux induced by inflammatory mediators in the spinal cord

Yanting Mao, Yulin Huang, Ying Zhang, Chenchen Wang, Hao Wu, Xinyu Tian, Yue Liu, Bailing Hou, Ying Liang, Hui Rong, Xiaoping Gu, Zhengliang Ma
Pages: 5100-5110
Published online on: 25 October 2019

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Article Open Access

Identification of whirlin domains interacting with espin: A study of the mechanism of Usher syndrome type II

Le Wang, Bo Wei, Xueqi Fu, Yuchen Wang, Yuan Sui, Junfeng Ma, Xianhui Gong, Jilong Hao, Shu Xing
Pages: 5111-5117
Published online on: 07 October 2019

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Case Report Open Access

Idiopathic renal hypouricemia: A case report and literature review

Cuiyu Wang, Jin Wang, Song Liu, Xinhua Liang, Yifan Song, Ling Feng, Lanxin Zhong, Xiaohua Guo
Pages: 5118-5124
Published online on: 04 October 2019

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Article Open Access

Effects of microRNA‑217 on high glucose‑induced inflammation and apoptosis of human retinal pigment epithelial cells (ARPE‑19) and its underlying mechanism

Hongxia Xiao, Zhen Liu
Pages: 5125-5133
Published online on: 30 October 2019

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Article Open Access

Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury

Junjie Wang, Dongdong Fu, Soulixay Senouthai, Yanwu You
Pages: 5134-5144
Published online on: 09 October 2019

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Article Open Access

Early‑onset epilepsy and microcephaly‑capillary malformation syndrome caused by a novel STAMBP mutation in a Chinese boy

Fangrui Wu, Ying Dai, Juan Wang, Min Cheng, Yanqin Wang, Xiujuan Li, Ping Yuan, Shuang Liao, Li Jiang, Jin Chen, Lisi Yan, Min Zhong
Pages: 5145-5151
Published online on: 17 October 2019

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Article Open Access

Effect of electrical stimulation combined with diet therapy on insulin resistance via mTOR signaling

Siqin Huang, Nianzhen Tang, Hongdi Zhao, Cheng‑Lin Tang
Pages: 5152-5162
Published online on: 30 October 2019

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Article Open Access

Nicotinamide phosphoribosyltransferase‑related signaling pathway in early Alzheimer's disease mouse models

Sanli Xing, Yiran Hu, Xujiao Huang, Dingzhu Shen, Chuan Chen
Pages: 5163-5171
Published online on: 30 October 2019

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Article Open Access

miR‑593 inhibits proliferation and invasion and promotes apoptosis in non‑small cell lung cancer cells by targeting SLUG‑associated signaling pathways Corrigendum in /10.3892/mmr.2021.12555 Retraction in /10.3892/mmr.2025.13490

Fang Wei, Mofei Wang, Zhen Li, Yong Wang, Yong Zhou
Pages: 5172-5182
Published online on: 29 October 2019

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Article Open Access

Dexmedetomidine improves cardiac function and protects against maladaptive remodeling following myocardial infarction

Hui Han, Daopeng Dai, Jinquan Hu, Jinzhou Zhu, Lin Lu, Guorong Tao, Ruiyan Zhang
Pages: 5183-5189
Published online on: 29 October 2019

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Article Open Access

Promotion of microglial phagocytosis by tuftsin stimulates remyelination in experimental autoimmune encephalomyelitis Corrigendum in /10.3892/mmr.2020.11042

Zheng Bao, Jinqi Hao, Yuhong Li, Fumin Feng
Pages: 5190-5196
Published online on: 31 October 2019

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Article Open Access

Kaempferol promotes bone formation in part via the mTOR signaling pathway

Jing Zhao, Jue Wu, Binwu Xu, Zhen Yuan, Yu Leng, Jun Min, Xiaoyong Lan, Jun Luo
Pages: 5197-5207
Published online on: 16 October 2019

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Article

miR‑486 acts as an oncogene and potential prognostic biomarker in renal cell carcinoma

Chengwen Sun, Caihong Sun, Yibin Zhou, Ganglong Yang, Guang Li, Congming Xiang, Xiqi Ding, Jian Sun
Pages: 5208-5215
Published online on: 25 October 2019

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Article

Long noncoding RNA MIAT: A potential role in the diagnosis and mediation of acute myocardial infarction

Mayra Azat, Xiaokelaiti Huojiahemaiti, Ranran Gao, Peng Peng
Pages: 5216-5222
Published online on: 23 October 2019

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Article

Oxyntomodulin attenuates TNF‑α induced neuropathic pain by inhibiting the activation of the NF‑κB pathway

Yu Zhang, Liyong Yuan, Yuebo Chen, Chunyan Lin, Guangyao Ye
Pages: 5223-5228
Published online on: 25 October 2019

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Article Open Access

Genetic analysis of monoallelic double MYH7 mutations responsible for familial hypertrophic cardiomyopathy

Bo Wang, Jing Wang, Li‑Feng Wang, Fan Yang, Lei Xu, Wen‑Xia Li, Yang He, Lei Zuo, Qian‑Li Yang, Hong Shao, Dan Hu, Li‑Wen Liu
Pages: 5229-5238
Published online on: 16 October 2019

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Article

Dynamic features of liver fibrogenesis and fibrosis resolution in the absence of matrix metalloproteinase‑9

Quanrongzi Wang, Xisheng Liu, Jie Zhang, Ling Lu, Min Feng, Jie Wang
Pages: 5239-5248
Published online on: 11 October 2019

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Article

Gallotannin attenuates 2‑deoxy‑D‑glucose‑induced dedifferentiation and endoplasmic reticulum stress through inhibition of inositol‑requiring enzyme 1 downstream p38 kinase pathway in chondrocytes

Su Min Kim, Yohan Han, Seon‑Mi Yu, Song Ja Kim
Pages: 5249-5256
Published online on: 25 October 2019

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Article

A simple, efficient and economical method for isolating and culturing human umbilical cord blood‑derived mesenchymal stromal cells

Junhe Zhang, Junli Zhao, Qinwen Mao, Haibin Xia
Pages: 5257-5264
Published online on: 23 October 2019

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Article

BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice

Huifeng Yang, Haocong Zhang, Yu Li, Liangbi Xiang, Jun Liu
Pages: 5265-5271
Published online on: 30 October 2019

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Article

Downregulation of miR‑138‑5p promotes non‑small cell lung cancer progression by regulating CDK8

Shigang Xing, Qinghua Xu, Xinlei Fan, Shanxia Wu, Feng Tian
Pages: 5272-5278
Published online on: 15 October 2019

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Article

Effect of ethanol extracts of Hericium erinaceus mycelium on morphine‑induced microglial migration

Chung‑Hsin Yeh, Li‑Wei Sun, Chang‑Mei Lai, Tzu‑Pei Yeh, Jong‑Ni Lin, Shiow‑Luan Tsay, Chin‑Chu Chen, Wan‑Ping Chen, Chien‑Min Chen, Ru‑Yin Tsai
Pages: 5279-5285
Published online on: 15 October 2019

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Article

ACSS2/AMPK/PCNA pathway‑driven proliferation and chemoresistance of esophageal squamous carcinoma cells under nutrient stress

Lei Mi, Yuepeng Zhou, Dan Wu, Qing Tao, Xuefeng Wang, Haitao Zhu, Xingyu Gao, Jingzhi Wang, Rui Ling, Jing Deng, Chaoming Mao, Deyu Chen
Pages: 5286-5296
Published online on: 09 October 2019

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Article Open Access

Gene expression profiling analysis reveals that the long non‑coding RNA uc.412 is involved in mesangial cell proliferation

Minyi Yu, Zheng Guan, Shanwen Li, Xianli Wen, Huimin Shi, Gaoting Qu, Xiaoyu Lu, Xianyi Zhu, Bin Wang, Qihua Feng, Weihua Gan, Aiqing Zhang
Pages: 5297-5303
Published online on: 16 October 2019

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Prognostic implications of aberrantly expressed methylation‑driven genes in hepatocellular carcinoma: A study based on The Cancer Genome Atlas

Jinzhong Li, Ning Chen, Xiaobing Gong
Pages: 5304-5314
Published online on: 25 October 2019

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Dendritic cell exosome‑shuttled miRNA146a regulates exosome‑induced endothelial cell inflammation by inhibiting IRAK‑1: A feedback control mechanism

Xin Zhong, Wei Gao, Runda Wu, Haibo Liu, Junbo Ge
Pages: 5315-5323
Published online on: 16 October 2019

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Gene synthesizing, expression and immunogenicity characterization of recombinant translation elongation factor 2 from Dermatophagoides farinae

Desheng Chen, Qinghui Fu, Jianli Lin, Chengshen Hu, Nana Huang, Ke Xin Chang, Baoqing Sun, Zhigang Liu
Pages: 5324-5334
Published online on: 31 October 2019

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Gene targets of sulforaphane in head and neck squamous cell carcinoma

Lanlin Hu, Hua Li, Eliot D. Lee, Jennifer R. Grandis, Julie E. Bauman, Daniel E. Johnson
Pages: 5335-5344
Published online on: 23 October 2019

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Downregulation of FSTL‑1 attenuates the inflammation injury during Streptococcus pneumoniae infection by inhibiting the NLRP3 and TLR4/NF‑κB signaling pathway

Liang Chen, Zhenshe Liu
Pages: 5345-5352
Published online on: 16 October 2019

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Potential function of microRNAs in thoracic aortic aneurysm and thoracic aortic dissection pathogenesis

Tugce Senturk, Arzu Antal, Tuba Gunel
Pages: 5353-5362
Published online on: 22 October 2019

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Correction Open Access

[Corrigendum] Differential miRNAomics of the synovial membrane in knee osteoarthritis induced by bilateral anterior cruciate ligament transection in rats

Jiangtao Zhou, Yina Zhao, Guangwen Wu, Bingbing Lin, Zuanfang Li, Xianxiang Liu
Pages: 5363-5363
Published online on: 18 October 2019

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October-2026 Volume 34 Issue 4

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Licoisoflavone A ameliorates adipose tissue dysfunction in diet‑induced obesity by promoting METTL3 expression

Shuangxi Tu, Xiaodan Wang, Zhenbo Wang, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 296
Published online on: 03 September 2026

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Interaction of circular RNAs with splicing factors in cervical cancer: Modulation, interplay and theranostics (Review)

Amahle Nyalambisa, Afra Basera, Ntombikayise Xelwa, Olalekan Fadebi, Zodwa Dlamini, Rahaba Marima
Article Number: 295
Published online on: 03 September 2026

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From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review)

Yuying Li, Ling Wei, Fang Sun, Huixia Wu, Xijun Sun, Yirong Gan, Xiaohua Kong
Article Number: 294
Published online on: 03 September 2026

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Resurrection biology: Melatonin as a modulator of anastasis (Review)

Alexandros Georgiou, Russel J. Reiter, Vassilis Zoumpourlis, Demetrios A. Spandidos
Article Number: 293
Published online on: 02 September 2026

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Correction Open Access

[Corrigendum] CLEC4M overexpression inhibits progression and is associated with a favorable prognosis in hepatocellular carcinoma

Qianle Yu, Kai Gao
Article Number: 292
Published online on: 01 September 2026

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Natural medicine‑empowered treatment of depression via restoring neurogenesis (Review)

Xiufen Zhong, Jingtao Gui
Article Number: 291
Published online on: 28 August 2026

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Article Open Access

POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy

Yongbo Ma, Xiaozhe Chen, Zixian Liu, Yulong Ma, Chunlei Hou, Yunfeng Li, Mingtai Gui, Bo Lu, Deyu Fu, Mingzhu Wang
Article Number: 290
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Human cytomegalovirus RL13 protein interacts with host NUDT14 protein affecting viral DNA replication

Guili Wang, Gaowei Ren, Xin Cui, Zhitao Lu, Yanping Ma, Ying Qi, Yujing Huang, Zhongyang Liu, Zhengrong Sun, Qiang Ruan
Article Number: 289
Published online on: 24 August 2026

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Autophagy: Mechanisms and therapeutic perspectives in intestinal metaplasia (Review)

Laifeng Wu, Lingchen Liao, Ziwei Xia, Qiao Zeng, An Huang, Zhiyong Cao
Article Number: 288
Published online on: 21 August 2026

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Unlocking the potential of microRNA as predictive biomarkers for efficacy and adverse events in immune checkpoint inhibitor therapy (Review)

Xi Wang, Baojun Duan, Jun Bai, Huitong Liu
Article Number: 287
Published online on: 20 August 2026

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Mitochondrial dysfunction‑driven ferroptosis in cerebral ischemia‑reperfusion injury: Mechanisms and therapeutic strategies (Review)

Jianhui Li, Annan Liu, Wei Gao, Liping Xing, Peihan Duan, Honglin Li
Article Number: 286
Published online on: 20 August 2026

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Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis

Junjian Chen, Wanyi Zhang, Tao Hong, Junsheng Wang, Chuan Chen, Ying Zhang, Mi Hu, Ning You, Jietao Huang
Article Number: 285
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons 

Man Yang, Naqi Lian, Yang Yu, Yaoqi Wang, Keliang Xie, Yonghao Yu
Article Number: 284
Published online on: 20 August 2026

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Deubiquitinating enzymes in kidney diseases: Molecular mechanisms, pathological roles and therapeutic opportunities (Review)

Qianqian Li, Yufang Ni, Zhaoyang Li, Jianchun Li, Li Wang
Article Number: 283
Published online on: 18 August 2026

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Biological mechanisms of atropine in myopia control (Review)

Qin Zhu, Guanglong Zhou, Lingguo Wang, Xuejiao Li, Zhijuan Hua, Jie Yin, Jieying Zhang, Yuan Zhou, Xiaofan Zhang, Allison Wilde, Yingting Zhu, Liping Xue
Article Number: 282
Published online on: 18 August 2026

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6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota

Xuezhi Yu, Yang Zhang, Konchun Sun, Rui Yang, Xingde Li, Xiuzhen Chen, Tiantian Li, Xiaolei Yang, Ming Li, Lu Liu, Fei Li, Baochun Shen
Article Number: 281
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival  

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma
Article Number: 280
Published online on: 17 August 2026

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Uric acid enhances tumor stemness in breast cancer cells by upregulating GMPS

Zhiying Wang, Mingzhang Huang, Yuanqi Zhang, Siqi Huang, Wei Lei, Xiaorong Shui
Article Number: 279
Published online on: 13 August 2026

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Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis

Le-Yi Huang, Yao Chen, Lin-Ran Song, Zhuo-Lin Zhong, Kamran Ali, Hui-Min Li, Qing-Feng Hu, Hong-Hua Hu
Article Number: 278
Published online on: 13 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑145‑5p suppresses fascin to inhibit the invasion and migration of cervical carcinoma cells

Shufang He, Guiyuan Yu, Ke Peng, Sisun Liu
Article Number: 277
Published online on: 12 August 2026

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Review

Research progress on drugs targeting mitochondria‑associated membranes for the treatment of atherosclerosis (Review)

Shaoying An, Wenhui Sun, Lizhou Shi, Hai Chen, Zhongcheng Mo
Article Number: 276
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

Liang Hao, Yuying Wan, Juhua Xiao, Qiang Tang, Huan Deng, Lu Chen
Article Number: 275
Published online on: 10 August 2026

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Article Open Access

Histone deacetylase 3‑mediated histone deacetylation combined with activating transcription factor 3 promotes renal fibrosis by inhibiting Klotho

Zhiying Yang, Xueling Wang, Wenhong Li, Hao Chen, Gang Liu
Article Number: 274
Published online on: 06 August 2026

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Mitochondrial quality control in acute liver injury and its therapeutic implications (Review)

Ziqiang Chen, Yunhe Wang, Yijing Li, Gang Cong, Yunhang Chu, Yunhui Bai, Yishuo Zhang, Liya Zhou
Article Number: 273
Published online on: 05 August 2026

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Article Open Access

STC1 promotes osteogenic differentiation and represses inflammation via inhibition of NF‑κB signaling in mesenchymal stromal cells

Chen Yang, Xin Li, Peng Wang, Yitong Chen, Erli Wu, Qian Chen, Jing Hu, Fu Zheng, Lamu Gongsang, Jiayu Li, Mengyuan Zhang, Jing Zhou, Bing Han, Amr A. Badreldin, Yuka Miyamoto, Jin Koo Kim, Insoon Chang, Jia Chang, Paul H. Krebsbach, Liyuan Huang, Xiaoping Xu, Xiaoyan Chen, Peng Deng, Qianming Chen, Lijie Fan
Article Number: 272
Published online on: 05 August 2026

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Review Open Access

Research progress on the protective effect and oxidative stress mechanism of rutin against liver injury (Review)

Teng Sun, Lei Ye
Article Number: 271
Published online on: 04 August 2026

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Role of microbial metabolites in the pathogenesis of hypertensive disorders of pregnancy: From short‑chain fatty acids to tryptophan metabolites (Review)

Fengyun Gao, Lili Wang, Guiyun Teng, Liqiong Shang
Article Number: 270
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Tumor promoter role of miR‑647 in gastric cancer via repression of TP73

Xiangqian Zhang, Min Zhang, Guifeng Wang, Ye Tian, Xiaolong He
Article Number: 269
Published online on: 03 August 2026

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Gut microbiota‑immune crosstalk in recurrent pregnancy loss: Mechanisms and therapeutic perspectives (Review)

Nanjian Luo, Han Hu, Xiaoting Zeng, Yi Huan Zhang, Qi Deng, En Ni Tang, Yu Hu
Article Number: 268
Published online on: 31 July 2026

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Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review)

Liqi Zhang, Shuxia Yang, Huiyan Wu, Hong Zhou
Article Number: 267
Published online on: 30 July 2026

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Role of CMTM6 in disease pathogenesis and clinical translation potential (Review)

Rongtou Huang, Danning Mo, Huitian Huang, Minmin Zhang, Wenhong Yu, Buqing Cao
Article Number: 266
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses

Yubo Xiao, Min Feng, Haiying Ran, Xiao Han, Xuegang Li
Article Number: 265
Published online on: 29 July 2026

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Advances in miR‑200c regulation of apoptosis, pyroptosis and autophagy in disease (Review)

Xiaona Wang, Hua Du, Yingxu Shi
Article Number: 264
Published online on: 28 July 2026

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Association between periodontitis and heart failure: Mechanisms and clinical implications (Review)

Xinyue Zhang, Xiaoli An
Article Number: 263
Published online on: 28 July 2026

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Article Open Access

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene CLOCK

Jiawen Yu, Chunmei Qian, Renye Que, Yi Zhou
Article Number: 262
Published online on: 28 July 2026

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Retraction Open Access

[Retracted] PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells

Jinhua Lu, Shengyou Lin, Zechen Lin, Xianlei Lin, Yuezhong Shen, Jingyang Su
Article Number: 261
Published online on: 27 July 2026

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UBE2A as a prognostic indicator across human cancers: Insights from multi‑omics and immune landscape analyses

Yun Wen, Pengfei Luo
Article Number: 260
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Sleep deprivation exacerbates lens‑induced myopia in association with ERK/NF‑κB pathway activation

Xueli Yang, Zhou Zhang, Chengbai Zhu, Jianbo Li, Wenting Gong, Ruirui Yang, Lipeng Guan
Article Number: 318
Published online on: 22 September 2026

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Advances in biomarkers of benzene exposure and toxicity: From mechanistic insights to occupational health applications (Review)

Yuanshe Huang, Zhenjun Xi, Jingxin Mao, Xiaobing Li
Article Number: 317
Published online on: 21 September 2026

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[Retracted] CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells

Long-Qiao Cao, Ya-Nan Wang, Ming Liang, Mei-Zhou Pan
Article Number: 316
Published online on: 21 September 2026

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Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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